Digital Commons Network^™

Harnessing The Human Gut Microbiota: An Emerging Frontier In Combatting Multidrug-Resistant Bacteria., Wenwen Ding, Yiwen Cheng, Xia Liu, Zhangcheng Zhu, Lingbin Wu, Jie Gao, Wenhui Lei, Yating Li, Xin Zhou, Jian Wu, Yongtao Gao, Zongxin Ling, Ruilai Jiang

Faculty Research 2025

Antimicrobial resistance (AMR) has become a major and escalating global health threat, undermining the effectiveness of current antibiotic and antimicrobial therapies. The rise of multidrug-resistant bacteria has led to increasingly difficult-to-treat infections, resulting in higher morbidity, mortality, and healthcare costs. Tackling this crisis requires the development of novel antimicrobial agents, optimization of current therapeutic strategies, and global initiatives in infection surveillance and control. Recent studies highlight the crucial role of the human gut microbiota in defending against AMR pathogens. A balanced microbiota protects the body through mechanisms such as colonization resistance, positioning it as a key ally in the fight …

From Gene Modules To Gene Markers: An Integrated Ai-Human Approach Selects Cd38 To Represent Plasma Cell-Associated Transcriptional Signatures., Basirudeen Syed Ahamed Kabeer, Bishesh Subba, Darawan Rinchai, Mohammed Toufiq, Taushif Khan, Marina Yurieva, Damien Chaussabel

Faculty Research 2025

BACKGROUND: Knowledge-driven prioritization of candidate genes derived from large-scale molecular profiling data for targeted transcriptional profiling assays is challenging due to the vast amount of biomedical literature that needs to be harnessed. We present a workflow leveraging Large Language Models (LLMs) to prioritize candidate genes within module M12.15, a plasma cell-associated module from the BloodGen3 repertoire, by integrating knowledge-driven prioritization with data-driven analysis of transcriptome profiles.

METHODS: The workflow involves a two-step process: (1) high-throughput screening using LLMs to score and rank the 17 genes of module M12.15 based on six predefined criteria, and (2) prioritization employing high-resolution scoring and …

Ct-Derived Fat Density As A Predictor Of Cause-Specific Mortality In Patients Undergoing Tavi: Findings From A Large Registry Subanalysis., Matej Pekař, Piotr Branny, Radim Špaček, Otakar Jiravský, Jan Novák, Jakub Balušík, Daniel Daniš, Jan Hečko, Marek Kantor, Bogna Jiravská Godula, Lubomír Blaha, Radek Neuwirth, Martin Šimek

Faculty Research 2025

Transcatheter aortic valve implantation (TAVI) is increasingly performed in older and frailer patients with severe aortic stenosis. Pre-procedural computed tomography (CT) scans at the third lumbar vertebra (CTL3) can estimate overall patient survival after TAVI [1, 2]. This subanalysis investigated whether CTL3 parameters can predict specific causes of death, potentially allowing for more tailored post-operative therapy.

Marmosets As Model Systems For The Study Of Alzheimer's Disease And Related Dementias: Substantiation Of Physiological Tau 3r And 4r Isoform Expression And Phosphorylation., Hasi Huhe, Sarah M Shapley, Duc M Duong, Fang Wu, Seung-Kwon Ha, Sang-Ho Choi, Julia Kofler, Yongshan Mou, Thais Rafael Guimaraes, Amantha Thathiah, Caroline M Watson, Lauren K H Schaeffer, Gregory W. Carter, Nicholas T Seyfried, Afonso C Silva, Stacey J Sukoff Rizzo

Faculty Research 2025

INTRODUCTION: Marmosets spontaneously develop pathological hallmarks of Alzheimer's disease (AD) including amyloid beta plaques. However, tau expression in the marmoset brain has been understudied.

METHODS: Isoforms of tau were examined by western blot, mass spectrometry, immunofluorescence, and immunohistochemical staining.

RESULTS: 3R and 4R tau isoforms are expressed in marmoset brains at both the transcript and protein levels across ages. Mass spectrometry analysis revealed that tau peptides in marmoset corresponded to the 3R and 4R peptides in human brain, with 3R predominating at birth and an ≈40%:60% 3R:4R ratios in adolescents and adults; tau was distributed widely in neurons, with localization …

Biological Databases In The Age Of Generative Artificial Intelligence., Mihai Pop, Teresa K Attwood, Judith A. Blake, Philip E Bourne, Ana Conesa, Terry Gaasterland, Lawrence Hunter, Carl Kingsford, Oliver Kohlbacher, Thomas Lengauer, Scott Markel, Yves Moreau, William S Noble, Christine Orengo, B F Francis Ouellette, Laxmi Parida, Natasa Przulj, Teresa M Przytycka, Shoba Ranganathan, Russell Schwartz, Alfonso Valencia, Tandy Warnow

Faculty Research 2025

SUMMARY: Modern biological research critically depends on public databases. The introduction and propagation of errors within and across databases can lead to wasted resources as scientists are led astray by bad data or have to conduct expensive validation experiments. The emergence of generative artificial intelligence systems threatens to compound this problem owing to the ease with which massive volumes of synthetic data can be generated. We provide an overview of several key issues that occur within the biological data ecosystem and make several recommendations aimed at reducing data errors and their propagation. We specifically highlight the critical importance of improved …

Replacing Non-Biomedical Concepts Improves Embedding Of Biomedical Concepts., Enock Niyonkuru, Mauricio Soto Gomez, Elena Casarighi, Stephan Antogiovanni, Hannah Blau, Justin T Reese, Giorgio Valentini, Peter N Robinson

Faculty Research 2025

Embeddings are semantically meaningful representations of words in a vector space, commonly used to enhance downstream machine learning applications. Traditional biomedical embedding techniques often replace all synonymous words representing biological or medical concepts with a unique token, ensuring consistent representation and improving embedding quality. However, the potential impact of replacing non-biomedical concept synonyms has received less attention. Embedding approaches often employ concept replacement to replace concepts that span multiple words, such as non-small-cell lung carcinoma, with a single concept identifier (e.g., D002289). Also, all synonyms of each concept are merged into the same identifier. Here, we additionally leveraged WordNet to …

Merritt-Putnam Symposium | Developmental And Epileptic Encephalopathies-Current Concepts And Novel Approaches., Rodney C Scott, Jenny Hsieh, Amy Mctague, J Matthew Mahoney, Catherine A Christian-Hinman

Faculty Research 2025

Developmental and epileptic encephalopathies (DEEs) are among the most severe and difficult to treat epilepsies. Two broad strategies for understanding the etiology and impacts of DEEs include genetic and complex adaptive systems approaches. This review, inspired by the 2024 Merritt-Putnam Symposium, describes current perspectives of DEE, identifies limitations of current views, and discusses potential novel ways forward. First, we discuss the rationale for a reevaluation of the role of seizures in the pathogenesis of cognitive and behavioral impairments in DEE. Second, we discuss newly emerging methods employing neural organoids to study brain development and DEE in vitro. Third, we present …

Comprehensive Single-Cell Aging Atlas Of Healthy Mammary Tissues Reveals Shared Epigenomic And Transcriptomic Signatures Of Aging And Cancer., Brittany Lynn Angarola, Siddhartha Sharma, Neerja Katiyar, Hyeon Gu Kang, Djamel Nehar-Belaid, Sunghee Park, Rachel Gott, Giray N Eryilmaz, Mark A Labarge, Karolina Palucka, Jeffrey Chuang, Ron Korstanje, Duygu Ucar, Olga Anczuków

Faculty Research 2025

Aging is the greatest risk factor for breast cancer; however, how age-related cellular and molecular events impact cancer initiation is unknown. In this study, we investigated how aging rewires transcriptomic and epigenomic programs of mouse mammary glands at single-cell resolution, yielding a comprehensive resource for aging and cancer biology. Aged epithelial cells exhibit epigenetic and transcriptional changes in metabolic, pro-inflammatory and cancer-associated genes. Aged stromal cells downregulate fibroblast marker genes and upregulate markers of senescence and cancer-associated fibroblasts. Among immune cells, distinct T cell subsets (Gzmk⁺, memory CD4⁺, γδ) and M2-like macrophages expand with age. …

Reproductive Experience Drives Changes In Behaviour And Physiology In Male California Mice, Peromyscus Californicus, Maria E. Colt, Priyanka Agarwal, David Kolb, Erica Glasper, Heidi Fisher

Faculty Research 2025

Paternal experience improves memory and reduces anxiety-like behaviour in males, but it is unclear whether these changes are due to mating, siring offspring or caregiving behaviour. Likewise, paternal males have larger testes, a measure of sperm production, but again, the effects of siring and caregiving experience are difficult to disentangle. We examined behavioural and physiological outcomes in three groups of male mice: (1) virgins, (2) males paired with sterile females (‘nonfathers’) and (3) experienced fathers (experiment 1). Compared to virgins and nonfathers, experienced fathers exhibited increased recognition memory (novel object recognition) and decreased anxiety-like behaviour (elevated plus maze). Virgin males, …

Cell-Based High-Content Approach For Sars-Cov-2 Neutralization Identifies Unique Monoclonal Antibodies And Pi3k Pathway Inhibitors., Carly R Cabel, Briana A Guzman, Elaheh Alizadeh, Shuaizhi Li, Cameron Holberg, Chonlarat Wichaidit, Darren A Cusanovich, Andrew L Paek, Gregory R J Thatcher, Koenraad Van Doorslaer, Rachel S Nargi, Rachel E Sutton, Naveenchandra Suryadevara, James E Crowe, Robert H Carnahan, Samuel K Campos, Curtis A Thorne

Faculty Research 2025

The sudden rise of the SARS-CoV-2 virus and the delay in development of effective therapeutics for mitigation made evident a need for ways to screen compounds that can block infection and prevent further pathogenesis and spread. However, identifying effective drugs that are efficacious against viral infection and replication with minimal toxicity for the patient can be difficult. Monoclonal antibodies were shown to be effective, but as the SARS-CoV-2 mutated, these antibodies became ineffective. Small-molecule antivirals were identified using pseudovirus constructs to recapitulate infection in nonhuman cells, such as Vero E6 cells. However, the impact was limited due to poor translation …

Influence Of Multi-Species Data On Gene-Disease Associations In Substance Use Disorder Using Random Walk With Restart Models., Everest U Castaneda, Sharon Moore, Jason A. Bubier, Stephen K Grady, Michael A Langston, Elissa J Chesler, Erich J Baker

Faculty Research 2025

A major challenge lies in discovering, emphasizing, and characterizing human gene-disease and gene-gene associations. The limitations of data on the role of human gene products in substance use disorder (SUD) makes it challenging to transition from genetic associations to actionable insights. The integration of data from multiple diverse sources, including information-dense studies in model organisms, has the potential to address this gap. We demonstrate a modified performance of the Random Walk with Restart algorithm when multi-species data is integrated in the heterogeneous network within the context of SUD. Additionally, our approach distinguishes among disparate pathways derived from the Kyoto Encyclopedia …

A Feasibility Study Of Enzymatic Methylation Sequencing Of Cell-Free Dna From Cerebrospinal Fluid Of Pediatric Central Nervous System Tumor Patients For Molecular Classification., Aaron M Taylor, Jody T Lombardi, Areeba Patel, Ariella Tamariz, Jonathan Martin, Markus J Bookland, David S Hersh, Evan Cantor, Xianyuan Song, Felix Sahm, Patrick Ks Ng, Joanna J Gell, Ching C Lau

Faculty Research 2025

BACKGROUND: Array-based DNA methylation profiling is the gold standard for central nervous system (CNS) tumor molecular classification, but requires over 100 ng input DNA from surgical tissue. Cell-free tumor DNA (cfDNA) in cerebrospinal fluid (CSF) offers an alternative for diagnosis and disease monitoring. This study aimed to test the utilization of enzymatic DNA methylation sequencing (EM-seq) methods to overcome input DNA limitations.

METHODS: We used the NEBNext EM-seq v2 kit on various amounts of cfDNA, as low as 0.1 ng, extracted from archival CSF samples of 10 patients with CNS tumors. Tumor classification was performed via MNP-Flex using CpG sites …

Intracranial Germ Cell Tumors: Advancement In Genomic Diagnostics And The Need For Novel Therapeutics., Kee Kiat Yeo, Joanna J Gell, Girish Dhall, Ching C Lau

Faculty Research 2025

INTRODUCTION: The outcomes for patients with intracranial germ cell tumors (GCT) has improved over the past few decades. However, there remains a lack of a consensus on a standard diagnostic and treatment approach of these tumors. The diagnostic work-up of intracranial GCT remains variable, and the treatment for patients with recurrent disease remains challenging.

METHODS: We review the current approach in the diagnosis and treatment of intracranial GCT. Given the heterogeneity of these tumors, we highlight the challenges and controversy with these conventional approaches.

RESULTS: We discuss the advancements in the understanding of the underlying genetic changes in intracranial GCT …

A Framework For Strengthening The Quantitative Skills/Reasoning Support Ecosystem At Small Liberal Arts Colleges, Laura J. Muller, Melissa Eblen-Zayas

Faculty Research 2025

We developed a framework for characterizing an institution’s quantitative skills/reasoning support ecosystem to consider how various activities contribute to student success in areas connected to students’ quantitative preparation. Through discussions with faculty and staff stakeholders at eight selective small liberal arts colleges, we established that the quantitative skills/reasoning support ecosystem at these institutions consists of four domains: bridge programs with a quantitative component, assessment of readiness, curricular on-ramps, and supplementary support for courses that require quantitative skills/reasoning. The framework includes questions about each domain that can be used by stakeholders in different institutional positions to reflect on existing efforts to …

The Cd123 Antibody-Drug Conjugate Pivekimab Sunirine Exerts Profound Activity In Preclinical Models Of Pediatric Acute Lymphoblastic Leukemia., Ben Watts, Christopher M Smith, Kathryn Evans, Andrew J Gifford, Sara M A Mohamed, Stephen W Erickson, Eric J Earley, Steven Neuhauser, Timothy M Stearns, Vivek M. Philip, Jeffrey Chuang, Patrick A Zweidler-Mckay, Sribalaji Lakshmikanthan, Emily L Jocoy, Carol J Bult, Beverly A Teicher, Malcolm A Smith, Richard B Lock

Faculty Research 2025

Antibody–drug conjugates (ADCs) combining monoclonal antibodies with cytotoxic payloads are a rapidly emerging class of immune‐based therapeutics with the potential to improve the treatment of cancer, including children with relapse/refractory acute lymphoblastic leukemia (ALL). CD123, the α subunit of the interleukin‐3 receptor, is overexpressed in ALL and is a potential therapeutic target. Here, we show that pivekimab sunirine (PVEK), a recently developed ADC comprising the CD123‐targeting antibody, G4723A, and the cytotoxic payload, DGN549, was highly effective in vivo against a large panel of pediatric ALL patient‐derived xenograft (PDX) models (n = 39). PVEK administered once weekly for 3 weeks resulted …

Exploring The Composition Of Placental Microbiome And Its Potential Origin In Preterm Birth., Marwa Saadaoui, Mohamed Nadhir Djekidel, Selvasankar Murugesan, Manoj Kumar, Duaa Elhag, Parul Singh, Basirudeen Syed Ahamed Kabeer, Alexandra Katharina Marr, Tomoshige Kino, Tobias Brummaier, Rose Mcgready, François Nosten, Damien Chaussabel, Annalisa Terranegra, Souhaila Al Khodor

Faculty Research 2025

INTRODUCTION: For years, the placenta was believed to be sterile, but recent studies reveal it hosts a unique microbiome. Despite these findings, significant questions remain about the origins of the placental microbiome and its effects on pregnancy and fetal health. Some studies suggest it may originate from the vaginal tract, while others indicate that oral bacteria can enter the maternal bloodstream and seed the placenta. However, research analyzing the vaginal, oral, and placental microbiomes within the same cohort is lacking. Additionally, it's unclear whether the placental microbiome differs between healthy pregnancies and those with complications like preterm birth (PTB), which …

Rapid Changes In Plasma Corticosterone And Medial Amygdala Transcriptome Profiles During Social Status Change Reveal Molecular Pathways Associated With A Major Life History Transition In Mouse Dominance Hierarchies., Tyler M Milewski, Won Lee, Rebecca L Young, Hans A Hofmann, James P Curley

Faculty Research 2025

Social hierarchies are a common form of social organization across species. Although hierarchies are largely stable across time, animals may socially ascend or descend within hierarchies depending on environmental and social challenges. Here, we develop a novel paradigm to study social ascent and descent within male CD-1 mouse social hierarchies. We show that mice of all social ranks rapidly establish new stable social hierarchies when placed in novel social groups with animals of equivalent social status. Seventy minutes following social hierarchy formation, males that were socially dominant prior to being placed into new social hierarchies exhibit higher increases in plasma …

Single-Cell And Bulk Transcriptional Profiling Of Mouse Ovaries Reveals Novel Genes And Pathways Associated With Dna Damage Response In Oocytes., Monique Mills, Chihiro Emori, Parveen Kumar, Zachary Boucher, Joshy George, Ewelina Bolcun-Filas

Faculty Research 2025

Immature oocytes enclosed in primordial follicles stored in female ovaries are under constant threat of DNA damage induced by endogenous and exogenous factors. Checkpoint kinase 2 (CHEK2) is a key mediator of the DNA damage response (DDR) in all cells. Genetic studies have shown that CHEK2 and its downstream targets, p53, and TAp63, regulate primordial follicle elimination in response to DNA damage. However, the mechanism leading to their demise is still poorly characterized. Single-cell and bulk RNA sequencing were used to determine the DDR in wild-type and Chek2-deficient ovaries. A low but oocyte-lethal dose of ionizing radiation induces ovarian DDR …

Are We Expert Enough? Confronting Self-Doubt Through Critical Friendship, Kristen Gregory, Mark Diacopoulos

Faculty Submissions

As we transitioned to the dissertation stage, we experienced an increased sense of vulnerability, uncertainty, and tension where we simultaneously felt expert and novice in our development as teacher-educators and researchers. We embarked on a self-study with critical friendship and unpacked our understanding of novice-expert identity, placed ourselves within the context of this understanding, and reframed our perceptions. This process clarified how our self-doubt impacted our novice-expert identity, allowed us to critique our perceptions through another’s lens, and enabled us to successfully move forward. We offer our experiences as a model to support students through similar periods of self-doubt.

Wild Horse Overpopulation- Consequences And Environmental Effects, Tessa M. Eslick Ms.

Undergraduate Theses, Professional Papers, and Capstone Artifacts

When considering wild horse overpopulation, there are many different facets of the issue that need to be addressed. Wild horse overpopulation is a significant issue across the American West, particularly on lands managed by the Bureau of Land Management( BLM). The largest populations are often found in Nevada, other states include California, Oregon, Utah, Wyoming, Washington, and Arizona. Whether there are thousands of horses on many acres of land, or hundreds spread across smaller reservations or public lands, the effects of their overpopulation remain as imminent as ever. Overpopulation is causing ecological damage and strain on resources leading to concerns …

Capstone Research On Missoula, Montana, Rental Market Impact On Undergraduate Students’ Well-Being, Alysa Curry, Aidan Rasmussen, Halston Witt, Tristan Clifford, Sadie Arnold

Undergraduate Theses, Professional Papers, and Capstone Artifacts

This research project examined how rental housing challenges in Missoula, Montana, impacts the well-being of students at the University of Montana and Missoula College. With rising rent prices and limited affordable housing options, students face growing stress related to finances, housing stability, and academic life. To explore this, we created a survey asking students about their living situations, financial pressures, social support, and mental health. We calculated a Well-being Score based on housing stress, social support, and future confidence to identify the biggest factors affecting student well-being.

Despite facing challenges in distributing the survey and gathering responses, the results revealed …

The Laramie Project, Otterbein Theatre And Dance Department

2024-2025 Season Productions

No abstract provided.

Llm-Guided Multimodal Information Fusion With Hierarchical Spatio-Temporal Graph Network For Sentiment Analysis, Yujie Jin, Yong Wang, Yuzhe Wang, Qiyang Chen, Bin Hu, Yanling Han, Chaoyin Ma, Witold Pedrycz

Department of Information Management and Business Analytics Faculty Scholarship and Creative Works

Multimodal sentiment analysis aims to attain a precise comprehension of emotions by integrating complementary textual, visual, and audio information. However, issues such as sentiment discrepancies between modalities, ineffective integration of multi-modal information, and the intricacy of order dependency significantly constrain the models' efficacy. The authors propose an LLM-guided Hierarchical Spatio-Temporal Graph Network (L-HSTGN). By multimodal large model feature enhancement, bidirectional spatio-temporal joint modeling, and dynamic gate fusion mechanism, they effectively address the aforementioned problems. Firstly, they produce cross-modal emotion pseudo-labels based on the multimodal large model, and the single-modal representation was optimized by combining adversarial regularization. Secondly, they develop a …

Iii.A.2 Displacement & Barriers To Home Ownership, Kim Rostan, Bria Harper, Jim Neighbors, Mark Byrnes

Crafting Democratic Futures

This document explains how systemic racism and discriminatory policies from the Civil War & Reconstruction period through the 20th century prevented African Americans in Spartanburg from building wealth through land ownership and home equity. It details barriers such as Black Codes, sharecropping, convict leasing, exclusion from New Deal programs, discriminatory housing policies, and urban renewal projects that displaced Black neighborhoods without providing equitable opportunities for economic advancement.

Iii.B.2 Educational Barriers, Kim Rostan, Bria Harper, Rylee Jorgensen

Crafting Democratic Futures

The document examines how historical segregation and systemic racism have shaped educational disparities in Spartanburg County, highlighting persistent inequities in school resources, teacher pay, and student outcomes. It concludes that these historical barriers continue to influence academic performance and post-secondary enrollment, with schools serving more diverse populations often facing lower proficiency rates despite high graduation rates.

Iii.F.2 Safety And Security, Kimberly Rostan, Bria Harper, Jim Neighbors

Crafting Democratic Futures

The document details the persistent and systemic violence against Black people in Spartanburg County from the end of the Civil War through the Civil Rights era, highlighting the role of groups like the Ku Klux Klan and Red Shirts in enforcing white supremacy through terror, intimidation, and murder. It emphasizes that this continuous threat of violence created lasting psychological trauma and served as a major barrier to economic and social progress for Black communities.

Recognizing The Risk: Enhancing Nurse Preparedness For Postpartum Hemorrhage Through Simulation-Based Education, Ishpreet Kaur

Nursing | Student Research Posters

Background: Postpartum hemorrhage (PPH) is a serious, often unexpected complication after childbirth involving excessive bleeding. It is a leading cause of maternal death and can happen quickly, even in healthy pregnancies. Risk factors may increase the chances of PPH, but it can also occur without warning. Nurses play a key role in recognizing early signs and taking quick action. However, delays still happen due to inconsistent training, unclear protocols, and lack of preparedness. Strengthening nurse education and improving emergency response systems are essential to improve care and achieve better outcomes for mothers. Objective: This study aims to evaluate the impact …

Preserving Memories, Building Relationships, Jamie H. Cochran

Doctor of Nursing Practice Projects

Loneliness among adults aged 65 and older is a significant health concern linked to negative physical and mental outcomes, especially in rural communities. This DNP project implemented a 4-week scrapbooking intervention within a faith-based rural community in North Carolina to reduce feelings of loneliness. Guided by Watson’s Theory of Human Caring, participants engaged in collaborative arts activities designed to foster social connection and emotional expression. The potential results of this project are multifaceted, including improved social engagement, emotional well-being, and strengthened community bonds. The findings support integrating creative, relationship-centered strategies into community nursing practice to enhance well-being among older adults.

Exploring Law Enforcement Officers' Experiences With Athletic Trainers And Work-Related Injury, Stephanie H. Clines, Rubie Gaudette, Amanda Wheeler, Jennifer Ostrowsk

Athletic Training Faculty Publications

Law enforcement is an emerging clinical setting for athletic trainers (ATs), yet little is known regarding law enforcement officers (LEOs) perceptions of the profession. This qualitative study following a general inductive approach explored LEOs' experiences with musculoskeletal injury and their interactions with ATs. Seven officers (N = 7) participated in one-on-one semi-structured interviews. Three themes emerged: (1) roles and responsibilities of ATs, (2) education and training, and (3) impact of injury on LEOs. While participants viewed ATs positively, they demonstrated limited understanding of the profession's scope and expertise. Participants commonly described managing musculoskeletal injuries on their own due to …

Adolescents Sexual Health Education Disparities: A Comparative Study Of Inclusion, Cultural Barriers, Access, Policy In Relation To Health And Long Term Outcomes​, Sofia Vega

Nursing | Student Research Posters

Currently, across the different states, sexual health education varies in a range of comprehensive sexual health education to limited sexual health education. These differences in curriculum are not only different from each other but also within themselves. This creates disparities in the knowledge and access among adolescents within their sexual health, which then creates a range of complications involving confidence in knowledge, pregnancy, STIs, and overall inclusion. When granting access to contraceptives on an educational campus, along with education on contraceptives, it allows students to access these tools in a safe environment and increases usage of condoms, lowering the risk …