Digital Commons Network^™

Class Iii Phosphatidylinositol-3 Kinase/Vacuolar Protein Sorting 34 In Cardiovascular Health And Disease, Yuanjun Shen, Jason Gleghorn

Pharmacy Faculty Scholarship

Phosphatidylinositol-3 kinases (PI3Ks) play a critical role in maintaining cardiovascular health and the development of cardiovascular diseases (CVDs). Specifically, vacuolar Protein Sorting 34 (VPS34) or PIK3C3, the only member of Class III PI3K, plays an important role in CVD progression. The main function of VPS34 is inducing the production of phosphatidylinositol 3-phosphate, which, together with other essential structural and regulatory proteins in forming VPS34 complexes, further regulates the mammalian target of rapamycin activation, autophagy, and endocytosis. VPS34 is found to have crucial functions in the cardiovascular system, including dictating the proliferation and survival of vascular smooth muscle cells and cardiomyocytes …

Minutes, College Of Liberal Arts Executive Committee Meeting, Thursday, January 16, 2025, College Of Liberal Arts Executive Committe

Executive Committee Minutes

No abstract provided.

Eng 1001g-011 College Composition I Critical Reading & Source Based Writing, Ann Hart

Fall 2024

No abstract provided.

The Chanticleer, 2025-01-16, Coastal Carolina University

The Chanticleer Student Newspaper

The editorially independent student produced weekly newspaper of Coastal Carolina University.

The Indiana Statesman, January 16, 2025, Indiana State University

Student Newspaper

Campus Resources: AACC; Stay ahead of your grades with tutoring; Dance and Donate to energize Friday

All Things Marian: Hymns For Our Lady Of Hope With Dr. Richard Lenar, University Of Dayton. International Marian Research Institute, Michele Foley, Richard E. Lenar

Podcast: All Things Marian

Transcript is available using the "Download" button.

The Minutes Of The Marshall University Staff Council Meeting, January 2025, Marshall University Staff Council

Staff Council Minutes

No abstract provided.

Process Evaluation Of The Hockey Fans In Training Lifestyle Intervention (For Men With Overweight Or Obesity)., Wendy M Blunt, Marisa L Kfrerer, Dawn P. Gill, Katie J Shillington, Brendan Riggin, Jennifer D Irwin, Brooke Bliss, Robert J Petrella

Department of Medicine Publications

BACKGROUND: Despite the proven relationship between lifestyle and morbidity and mortality, rates of chronic disease (e.g. obesity) continue to rise in paradox to the myriad of studies supporting lifestyle behaviour change. Men have been less likely to seek out preventative care or lifestyle programs, putting them at risk. In response, Hockey Fans In Training (Hockey FIT) was developed as a group-based, lifestyle intervention leveraging the draw of hockey fandom to engage middle-aged men with overweight or obesity in lifestyle change. Encouraging pilot study results informed the optimization and delivery of the intervention through a cluster randomized controlled trial in 42 …

2024-2025 Master Of Music Recital - Brenda Lorenzo (Collaborative Piano), Brenda Lorenzo, Giah Bush, Brooke Gunter, Nataniel Farrar

Master of Music Recitals

No abstract provided.

Oncogenic Potential Of Truncated-Gli3 Via The Gsk3Β/Gli3/Ar-V7 Axis In Castration-Resistant Prostate Cancer, Jawed Siddiqui, Gunjan Sharma, K.M. Abdullah, Jyoti Kaushal, Pratima Raut, Sushanta Halder, Zahraa W. Alsafwani, Seema Parte, Parthasarathy Seshacharyulu, Surinder Batra, Subodh Lele

Cell and Molecular Biology Publications

The functional activation of the androgen receptor (AR) and its interplay with the aberrant Hh/Gli cascade are pivotal in the progression of castration-resistant prostate cancer (CRPC) and resistance to AR-targeted therapies. Our study unveiled a novel role of the truncated form of Gli (t-Gli3) in advancing CRPC. Investigation into Gli3 regulation revealed a Smo-independent mechanism for its activation. Despite lacking a transactivation domain, t-Gli3 relies on androgen receptor variant 7 (AR-V7) for its action. Mechanistically, Gsk3β activation led to the t-Gli3 generation, and inhibition of Gsk3β supported the accumulation of full-length Gli3 expression through a non-canonical mechanism. Knockdown of Gsk3β …

Gec Meeting Minutes For Jan 16, 2025, General Education Committee

General Education Committee Minutes

No abstract provided.

Met 302-102: Analysis And Design Of Machine Elements Ii, Ahmed Belal

School of Applied Engineering and Technology Syllabi

No abstract provided.

Priority Competencies For Designated Education Officers In The Veterans Health Administration, Duane R. Bidwell, Anita Samuel, Ronald M. Cervero, Steven J. Durning, Sherri L. Stephan, Erin L. Patel, Marjorie A. Bowman, Holly S. Meyer

Population and Public Health Sciences Faculty Publications

Designated Education Officers (DEOs) at Veteran Health Administration (VHA) hospitals are senior educational leaders tasked with oversight of all clinical training at a particular facility. They prioritize dozens of tasks and responsibilities each day, from educational policy and strategy to staff management, financial planning, onboarding of trainees, and facility planning and management. Clarifying priority competencies for the role can help executives recruit, appoint, and evaluate capable personnel and promote effective, efficient performance. Using a federally developed method of competency analysis, researchers consulted a panel of subject-matter experts to identify priority competencies for DEOs, using data from a 2013 study that …

Vip Embassadors Gain Insight, Give Back To Fhsu Community, January 16, 2025, Tisa Mason Ed.D.

Heart of a Tiger Columns

No abstract provided.

Brief Of Criminal Law Professors Andrea Roth And J.D. King As Amici Curiae In Support Of Petitioner, Lesh V. United States, U.S. Supreme Court Docket No. 24-654, David B. Owens

Court Briefs

QUESTION PRESENTED

Article III of the Constitution provides that “[t]he Trial of all Crimes, except in Cases of Impeachment, shall be by Jury.” And the Sixth Amendment provides that “[i]n all criminal prosecutions,” the accused shall enjoy the right to trial by jury.

The question presented is: Whether the Constitution’s dual guarantee of trial by jury contains an unstated exception for “petty” offenses.

Practicing And Assessing Skills Of Interpreting Culture And Sensitivity Reports, Lana Gettman

Faculty Research ​and Publications

No abstract provided.

African American Males' Perceptions Of Factors Affecting Their Decision To Not Attend College After Graduating From High School: A Qualitative Instrumental Case Study, Rawle Hamilton

Student Theses and Dissertations

This qualitative instrumental case study aimed to examine the factors that influence the decision of African American males who graduated from high-poverty high schools in New York City and decided not to attend college. A qualitative instrumental case study research design was done through the use of one-on-one, semi-structured interviews with 12 African American males who graduated from urban, high-poverty high schools in New York City between 2018 and 2023. Purposive and snowball sampling of 12 African American male alumni were utilized in this study, and the data source was alumni from urban, high-poverty high schools in New York City. …

Qualitative Study Of Barriers That Contribute To English Language Learners Academic Underperformance In Middle School Grades 6-8, Marcus Tremayne Holbert

Student Theses and Dissertations

The academic underperformance of English Language Learners (ELL) in middle schools remains a critical issue within the U.S. educational system. ELL students face a variety of obstacles that impact their academic achievement, such as language barriers and a lack of adequate support. This qualitative phenomenological study aimed to explore the barriers contributing to the academic struggles of ELL students in grades 6-8 in central Mississippi, focusing on the lived experiences of core subject teachers. The study sought to understand how these barriers affect instructional practices and student outcomes, particularly within the context of middle school education. The research was guided …

A Qualitative Study On The Opportunities And Barriers Of Female Superintendents In The Northern Region Of Missouri, Rondalyn Vaughn

Student Theses and Dissertations

This qualitative phenomenological study aimed to explore the experiences of female superintendents in leadership positions, focusing on the opportunities and barriers they faced on the journey to the superintendency and in the position of superintendent. Women are underrepresented in the superintendency in the female-dominated educational field. The study examined the role of gender in leadership by identifying the barriers and opportunities women experienced along the path to the superintendency and in the superintendent position. Liberal Feminist Theory was adopted as a guiding framework, focusing on the effective practices, opportunities, and challenges faced by female superintendents. The liberal feminist theory was …

A Study Of The Sense Of Teaching Self-Efficacy Among Emergency Certified Teachers In A Rural Eastern Oklahoma School District, Matthew J. Brunk

Student Theses and Dissertations

There is a teacher shortage in Oklahoma. To address this teacher shortage, the Oklahoma Department of Education has eased restrictions by providing an alternative pathway into the classroom called emergency-certification. The lack of traditionally prepared teachers entering the profession, coupled with untrained emergency-certified teachers entering the classroom instead, impacts students across the state. The purpose of this qualitative case study was to examine emergency-certified teachers' perceived sense of self-efficacy regarding their teaching pedagogy and classroom management in a rural Oklahoma district. Ten participants were chosen from six different rural school districts in eastern Oklahoma. Each participant was in either their …

Exploring Science Education Teaching Practices Within The Homeschool Community Of West Michigan, Amanda Syers

Student Theses and Dissertations

Parental perception of the importance of science education and parental perceptions and use of active learning and inquiry-based practices in the context of homeschool science education represent a clear gap in the existing literature. This quantitative survey research study was designed to discover, analyze, and quantify parents' perceptions of the importance of science education and the science education practices used in homeschools across West Michigan through a constructivist framework lens. Using a novel survey instrument specifically designed for this study, a pilot test and subsequent anonymous survey were administered using snowball sampling methodology to collect data to answer three research …

The Influence Of Principal Leadership On Collective Teacher Efficacy, Mikaela Marie Schaller

Student Theses and Dissertations

This study explored the relationship between principal leadership style and collective teacher efficacy in K-12 schools across five districts in South Carolina. The research problem addressed how different leadership styles—transformational, transactional, and passive-avoidant—affect teachers’ collective beliefs in their ability to positively influence student outcomes. A correlational quantitative research design was employed to examine the relationship between leadership style and collective teacher efficacy. The guiding theoretical framework was based on transformational leadership theory. Data was collected using the Multifactor Leadership Questionnaire. Descriptive statistics, Pearson’s correlation, and one-way ANOVA were used to analyze the data and answer the research questions. The findings …

Workforce Development Initiatives To Improve The Labor Force In Rural Communities: A Case Study, Danielle K. Pugsley

Student Theses and Dissertations

This qualitative case study explored stakeholders' perceptions in Baxter County, Arkansas, regarding workforce development initiatives at Mountain Home High School Career Academies and Arkansas State University-Mountain Home. The purpose was to understand if these initiatives met local employers' needs and contributed to creating a skilled and educated labor force, thereby enhancing the area's economic vitality. The study, guided by the Chaos Theory of Careers and the Pathways System Framework, included 15 in-person interviews with representatives from secondary and post-secondary education, business leaders, and workforce development professionals. Participants, selected through purposeful sampling, were asked five identical open-ended questions to understand the …

Examining Teacher’S Experience Of Using Developmentally Appropriate Practices For Improving Mississippi Academic Assessment Program Reading Scores, Kimberly L. Chambers

Student Theses and Dissertations

Examining Teacher’s Experience of Using Developmentally Appropriate Practices for Improving Mississippi Academic Assessment Program This study explored the impact of developmentally appropriate practices (DAP) on reading test scores as measured by the Mississippi Academics Assessment Program (MAAP) for students in grades 3-5. The research problem is centered on the potential disconnect between traditional teaching methods and the developmental needs of students, which negatively influenced their reading achievement. The study was particularly relevant to educators, policymakers, and students in elementary education who are directly impacted by the effectiveness of instructional practices. The purpose of this qualitative phenomenological study was to examine …

Cardozo Law Receives Top Marks From Prelaw Magazine, Benjamin N. Cardozo School Of Law

Cardozo Law News Archive

Cardozo Law earned multiple A+ rankings from preLaw Magazine in 2024–2025 for excellence in Dispute Resolution, Business Law, Entertainment Law, Trial Advocacy, and International Law, highlighting the school’s nationally recognized programs and hands-on learning opportunities.

Artificial Intelligence And The Urgency Of The Digitally Literate Instructor In Secondary Education, Evan Kyle Calderon

Masters Theses

The formative school years that comprise secondary education, defined as grades 6th through 8th, pave the way for student success in their foreseeable academic careers. More so than ever, the relationship between technology and student experience has significantly impacted students’ overall academic success. With the encroaching wave of artificial intelligence as a societally necessary tool, the days are fast approaching when AI will become commonplace in the classroom, for which educators of the aforementioned grade levels are overwhelmingly unprepared. In addressing the alarming lack of initiative from higher positions in the education hierarchy, an analysis of the reasons for this …

How The Flock Falters: An Analysis Of Apostasy In The Shepherd Of Hermas, Justin R. Bamba

Masters Theses

This study provides a detailed analysis of apostasy as it is expressed in the Shepherd of Hermas. Drawing from the work of B.J. Oropeza, the study offers a threefold analysis that identifies the Christian community in danger, the nature of apostasy as it pertains to this community, and the consequences of such apostasy. Special attention is devoted to Vision 3 and Similitudes 8-9 for their vivid Tower motif, a unique literary device by which the author expresses the hope and limitations of repentance, community identity, and the causes and consequences for separation from this community—all of which contribute to a …

The Importance Of Metaphysical Christian Screenplays, Francisca Dominguez Fuentes

Masters Theses

"HEAVEN AND EARTH, I AM" is a metaphysical screenplay that profoundly explores the universal theme of love. It parallels the Days of Noah and the Book of Revelation, warning humanity about the serious consequences of living without God daily. The screenplay emphasizes the urgency of this warning regarding the spiritual dangers arising from an alliance between the secular government and the church. It also examines the Three Angels' Message as described in Revelation, along with the prophetic teachings of the Bible presented by Daniel, Isaiah, and Ezekiel. The work serves as a reminder that the first judgment occurred through water, …

Timeless: A Sanctuary In Libraries, Taylor D. Vaughan

Masters Theses

This Master of Fine Arts Creative Writing thesis focuses on the literary element: character development. It includes a vision and background for the thesis project as a whole. An analysis of characters involved in wartime conflict will focus on William Shakespeare’s tragedies Macbeth and Hamlet and various characters in C.S. Lewis’s Chronicles of Narnia. The creative manuscript that concludes the thesis incorporates fantasy and war genres and character development research. The manuscript aims to shed light on traumatic events in our modern world rather than use escapism in fantasy to ignore them.

Young Adult Fiction Through The Years: An Analysis Of What Readers Want, Treanna Greenwood

Masters Theses

In this literary critique, I discuss the advantages of reading young adult fiction, specifically fantasy. I define what young adult fantasy is, and then analyze some of the most famous young adult book series and discuss how popular they are and how they contribute to the genre. I also discuss works that are relevant to the creative piece I am submitting and explain why my piece has a place in the world of young adult fantasy. Finally, I acknowledge what I hope to contribute to the field.