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Articles 242521 - 242550 of 5207136
Full-Text Articles in Entire DC Network
The Influence Of Meme Culture On The Perception Of Japanese Music: A Survey Of Dolphin In Town-Kingo Hamada, Salsabila Alfajri, Bambang Wibawarta
The Influence Of Meme Culture On The Perception Of Japanese Music: A Survey Of Dolphin In Town-Kingo Hamada, Salsabila Alfajri, Bambang Wibawarta
International Review of Humanities Studies
The research aims to explore the influence of meme culture on the perception of Japanese music in the digital era, specifically analyzing the impact of meme culture on the song "Dolphin in Town" by Kingo Hamada. This study utilized quantitative methods, with surveys as the main technique for data collection. The results showed that meme culture plays an important role in introducing songs and artists that may not have previously received attention. The study also highlights the diverse impacts of meme culture on the perception of Japanese music, including its influence on popularizing, accepting, and interpreting music in various ways. …
Cultural Discount: Breakthrough Point Of China's Tv Drama Exports To Southeast Asia, Lingxing Li
Cultural Discount: Breakthrough Point Of China's Tv Drama Exports To Southeast Asia, Lingxing Li
International Review of Humanities Studies
Driven by China's "Going Global" strategy, the international influence of Chinese TV series continues to grow. As a key vehicle of China's cultural soft power, these TV series have significantly bolstered China's global cultural presence, particularly in Southeast Asia, by showcasing China's rich history and contemporary societal changes. Despite certain geographical and cultural similarities between China and Southeast Asia, cultural differences still present challenges to the dissemination of Chinese TV dramas, particularly in areas such as language, values, and religious beliefs. This paper not only analyzes effective strategies for mitigating "cultural discounts" but also challenges the traditional one-dimensional view of …
Understanding The Transmission Of Deepavali Culture In Malaysia From The Perspective Of The "Circuit Of Culture ", Su Zihua, Mochamad Aviandy
Understanding The Transmission Of Deepavali Culture In Malaysia From The Perspective Of The "Circuit Of Culture ", Su Zihua, Mochamad Aviandy
International Review of Humanities Studies
As an important traditional festival in India, Deepavali carries profound cultural and religious connotations and has spread widely across Southeast Asia. Malaysia has become a typical example for articleing the transmisi of Deepavali due to its large Indian population and diverse cultural circulation. This article adopts a qualitative research method, gathering data and literature from various platforms and deeply analyzing three aspects of Deepavali in Malaysia: representation and identity, production and consumption, and regulation.The article finds that its cultural symbols construct Indian identity, and the multicultural integration of elements promotes the identification of shared values. Various activities and advertisements during …
The Coloniality Of Gender In Sports And Education: Colonial Legacies Of The Philippines’ Modern Gender System In Rookie (2023), Hestia Dwi Pratiwi, Darmoko Darmoko
The Coloniality Of Gender In Sports And Education: Colonial Legacies Of The Philippines’ Modern Gender System In Rookie (2023), Hestia Dwi Pratiwi, Darmoko Darmoko
International Review of Humanities Studies
This article discusses the lasting impact of colonial-era policies on the gender system portrayed in the Filipino LGBT coming-of-age movie "Rookie" (2023) by analyzing the gendered notions in sports and education. Rookie, directed by Samantha Lee, tells the story of Maria "Ace" Asuncion who is navigating and exploring life as a transfer student learning to master volleyball. As a rookie or newbie at school and in the sport, Ace comes across gendered notions in sports and education that reveal the state of the gender system. Using the concept of 'Coloniality of Gender' by Maria Lugones, this paper …
The Systematics Of Online Debt Collection Speech In Indonesian, Filia Filia Dr., Muhammad Rifqi Herjoko
The Systematics Of Online Debt Collection Speech In Indonesian, Filia Filia Dr., Muhammad Rifqi Herjoko
International Review of Humanities Studies
This study examines the discourse systematics used in the online loan collection speeches in the Indonesian language. Online loans are one of the financial services that are widely used by the people nowadays. However, the efforts to collect these loans have raised issues within the community. This study aims to elaborate on the speech acts and systematics forming the discourse of online loan collection. This study is using 50 screenshots of online loan collection messages on Instagram accounts as the data source. Research data is in the form of speeches used by the creditors to collect debt from the debtors. …
Evaluation Of The Accuracy Of Instagram Translation Feature In Interpreting Islamic Arabic Poetry, Falen Hamzah Al-Agil, Basuni Imamuddin
Evaluation Of The Accuracy Of Instagram Translation Feature In Interpreting Islamic Arabic Poetry, Falen Hamzah Al-Agil, Basuni Imamuddin
International Review of Humanities Studies
This study focuses on evaluating the capabilities of Instagram translation feature in translating Arabic Islamic poetry, a literary genre rich in linguistic nuances and cultural context. Employing a qualitative methodology, this research conducts a comprehensive comparative analysis between the automatic translations produced by Instagram and manual translations done by experts. The findings reveal that, despite being useful, Instagram's translation feature often fails to fully capture the essence of Arabic Islamic poetry, with significant errors in understanding context and language nuances. These errors include inaccuracies in translating key words and difficulties in interpreting deeper meanings often closely tied to cultural and …
Complexities Behind The Javanese Shrounds: Unraveling Textile Symbolism For The Dead Through Mikhail Bakhtin’S Heteroglossia, Asha Kun Nayla Faizin, Ganang Dwi Kartika
Complexities Behind The Javanese Shrounds: Unraveling Textile Symbolism For The Dead Through Mikhail Bakhtin’S Heteroglossia, Asha Kun Nayla Faizin, Ganang Dwi Kartika
International Review of Humanities Studies
The shroud, a textile used to wrap and accompany humans in death, is far from a simple object. Within Islamic traditions, the white cloth applied to the deceased's body takes on various changes, modifications, and deeper meanings when individuals contextualize their own beliefs and experiences through it. This study focuses on the shroud's role in Islamic death rituals in Java, revealing a multiplicity of meanings as theorized by Mikhail Bakhtin's concept of heteroglossia. By employing a pragmatic semiotic approach, this research interprets and analyses the symbols that emerge from the contextualization of these textiles within Javanese death rituals. The study’s …
Towards Resolution: Comparative Lessons For Advancing Peace And Justice In Papua, Tagor Hutapea, Alexander Evan
Towards Resolution: Comparative Lessons For Advancing Peace And Justice In Papua, Tagor Hutapea, Alexander Evan
International Review of Humanities Studies
The conflict in Papua represents a complex interplay of identity, sovereignty, and historical grievances, shaped by structural violence and socio-political exclusion. This study explores strategies for advancing peace-building and justice in Papua, drawing on Johan Galtung’s theory of peace and conflict and comparative lessons from the Aceh conflict in Indonesia and the Irish Republican Army’s (IRA) struggle in South Ireland. The findings emphasize the importance of addressing root causes such as historical injustices, economic inequality, and cultural exclusion. Inclusive governance and dialogues that respect ethnic diversity and local identities are critical to creating sustainable solutions. Case studies reveal that effective …
Social Media Optimization Of Ramampa Resto & Bar As A Visual Strategy, Monique Pricilya Oei, Aniendya Christianna
Social Media Optimization Of Ramampa Resto & Bar As A Visual Strategy, Monique Pricilya Oei, Aniendya Christianna
International Review of Humanities Studies
In the digital era, social media has become an important marketing tool for businesses, including the culinary industry. This study examines the use of motion graphics to develop the social media presence of Rarampa Resto and Bar, a restaurant serving Manado cuisine and healthy MSG-free food, located in South Jakarta. Although the restaurant has a loyal customer base, particularly from the 40-60 age group, its social media content fails to attract younger audiences, especially millennials, who seek unique and authentic culinary experiences. This study suggests that Rarampa's social media content, which mainly focuses on event photography and the restaurant's ambiance, …
The Construction Of The Image Of The “Ideal Wife” In Intercultural Marriages: A Case Study On The Youtube Video “Younger Singapore Men Looking For Vietnam Brides, Li Jie
International Review of Humanities Studies
This study explores the process of constructing the image of the “ideal wife” in intercultural marriages, using the video Younger Singapore Men Looking for Vietnam Brides as a case study. It analyzes the economic and cultural motivations of Singaporean men in choosing Vietnamese wives. By applying Judith Butler’s theory of gender performativity and Henri Tajfel’s social identity theory, the study examines how Vietnamese brides are symbolized as the “ideal partner” and how this phenomenon reflects modern gender role conflicts and identity reconstruction. Through an analysis of interviews in the video and relevant comments, the research reveals the dynamic interaction between …
Exploring The Ontological Basis Of Law: Joseph Raz's Views On Normativity Within The Framework Of Legal Realism, Artha Debora Ads Silalahi, Rizal Mustansyir, Sindung Tjahyadi
Exploring The Ontological Basis Of Law: Joseph Raz's Views On Normativity Within The Framework Of Legal Realism, Artha Debora Ads Silalahi, Rizal Mustansyir, Sindung Tjahyadi
International Review of Humanities Studies
This study explores the moral ontology of law within the framework of Legal Realism, contextualizing law as both a social institution and an institution of justice. Drawing on Joseph Raz's perspectives on practical reason, normativity, and the foundations of norms, the analysis examines how law, as a practical guide, inherently carries moral dimensions in regulating social interactions and pursuing justice. Legal Realism frames law as a dynamic product of human interaction within a social context, while Raz's philosophical insights illuminate the interplay between practical reasoning, normativity, and legal structures. By focusing on the moral underpinnings of legal norms, this paper …
The Intricate Relationship Between Parents, Teachers And Media In Their Context Of Nation-Building, Emmanuel Olumuji
The Intricate Relationship Between Parents, Teachers And Media In Their Context Of Nation-Building, Emmanuel Olumuji
International Review of Humanities Studies
This study examines the intricate relationship between parents, teachers, and media in the context of nation-building, emphasizing their collective role in shaping societal values and fostering holistic development. Drawing insights from scholarly literature and empirical studies, the study considers the influence of parents, teachers, and media on child development, moral education, and civic engagement. The study underscores the pivotal role of educators in instilling moral values, critical thinking skills, and civic responsibility among students, thereby contributing significantly to the development of a nation's human capital. Moreover, the study highlights the media's potential as a catalyst for social change, advocating for …
China's Cultural Diplomacy And Its Engagement With The Peranakan Community In Malacca, Kotchaphop Kornphetcharat, Lee Yuen Thien
China's Cultural Diplomacy And Its Engagement With The Peranakan Community In Malacca, Kotchaphop Kornphetcharat, Lee Yuen Thien
International Review of Humanities Studies
China's cultural diplomacy utilizes a range of strategies, including cultural exchange programs, media outreach, and people-to-people interactions, to further its national interests and enhance its international image. The primary aims are to foster a positive perception of China, build mutual understanding and trust with other nations, and expand China's cultural and economic influence. The overseas Chinese community in Southeast Asia has been recognized as a crucial conduit for advancing Chinese cultural policy globally. Recently, the Chinese government has conducted official visits to the Baba & Nyonya Heritage Museum in Malacca, Malaysia, exemplifying its efforts to engage with the local community. …
Plurality Of Countable Nouns In Chinese And Indonesian: Morphological And Syntactic Perspectives With Pedagogical Implications, Hatmi Idris
International Review of Humanities Studies
This study investigates the plural meaning and expression of countable nouns in Chinese and Indonesian from morphological and syntactic perspectives and explores implications for language pedagogy. Although both languages encode plurality, they employ distinct mechanisms, which may pose challenges for Indonesian learners of Chinese. Using a qualitative, literature-based approach, data were drawn from scholarly studies, Chinese teaching materials, and reference sources such as dictionaries. Analysis focused on morphological markers, including affixation and reduplication, as well as syntactic structures, such as numeral–classifier phrases and quantifiers constructions. The findings show that Chinese expresses plurality through the suffix –men, classifier-based syntactic patterns, …
A Shocking Outcome: Cardioversion-Induced Flash Pulmonary Edema, Glenda Muguruza
A Shocking Outcome: Cardioversion-Induced Flash Pulmonary Edema, Glenda Muguruza
All Publications
Atrial fibrillation (AF) is the most common major cardiac rhythm disorder in adults and causes considerable morbidity and mortality, particularly in elderly patients. We present the case of a 75-year-old female admitted for acute heart failure with a history of AF and recurrent heart failure exacerbations. Despite aggressive medical management with amiodarone and diuretics, the patient continued to deteriorate. The cardiology team recommended electrical cardioversion to re-establish a normal sinus rhythm. By doing so, the patient developed flash pulmonary edema after the procedure and required immediate intubation with mechanical ventilation. There was a need for tracheostomy to facilitate prolonged ventilatory …
2025-01-30 Surveying Added Work For Instructors - Presentation, Morehead State University. Faculty Senate., Annie Adams
2025-01-30 Surveying Added Work For Instructors - Presentation, Morehead State University. Faculty Senate., Annie Adams
Faculty Senate Records
A presentation delivered on January 30, 2025 by Annie Adams to the Faculty Senate on added workload and responsibilities by the administration to instructors.
2025-01-30 Faculty Senate Meeting Minutes, Morehead State University. Faculty Senate.
2025-01-30 Faculty Senate Meeting Minutes, Morehead State University. Faculty Senate.
Faculty Senate Records
Faculty Senate meeting minutes from January 30, 2025.
Plasmids Encode And Can Mobilize Onion Pathogenicity In Pantoea Agglomerans, Gi Yoon Shin, Jo Ann Asselin, Amy Smith, Brenna Aegerter, Teresa Coutinho, Mei Zhao, Bhabesh Dutta, Jennie Mazzone, Ram Neupane, Beth Gugino, Christy Hoepting, Manzeal Khanal, Subas Malla, Claudia Nischwitz, Jaspreet Sidhu, Antoinette Machado Burke, Jane Davey, Mark Uchanski, Michael L. Derie, Lindsey J. Du Toit, Stephen Stresow-Cortez, Jean M. Bonasera, Paul Stodghill, Brian Kvitko
Plasmids Encode And Can Mobilize Onion Pathogenicity In Pantoea Agglomerans, Gi Yoon Shin, Jo Ann Asselin, Amy Smith, Brenna Aegerter, Teresa Coutinho, Mei Zhao, Bhabesh Dutta, Jennie Mazzone, Ram Neupane, Beth Gugino, Christy Hoepting, Manzeal Khanal, Subas Malla, Claudia Nischwitz, Jaspreet Sidhu, Antoinette Machado Burke, Jane Davey, Mark Uchanski, Michael L. Derie, Lindsey J. Du Toit, Stephen Stresow-Cortez, Jean M. Bonasera, Paul Stodghill, Brian Kvitko
Biology Faculty Publications
Pantoea agglomerans is one of four Pantoea species reported in the USA to cause bacterial rot of onion bulbs. However, not all P. agglomerans strains are pathogenic to onion. We characterized onion-associated strains of P. agglomerans to elucidate the genetic and genomic signatures of onion-pathogenic P. agglomerans. We collected > 300 P. agglomerans strains associated with symptomatic onion plants and bulbs from public culture collections, research laboratories, and a multi-year survey in 11 states in the USA. Combining the 87 genome assemblies with 100 high-quality, public P. agglomerans genome assemblies we identified two well-supported P. agglomerans phylogroups. Strains causing severe …
Student Library News - Early Spring 2025, Rit Libraries
Student Library News - Early Spring 2025, Rit Libraries
RIT Digital Archives
No abstract provided.
The Pulse - January 30, 2025, Unm Hsc Marketing & Communications
The Pulse - January 30, 2025, Unm Hsc Marketing & Communications
The Pulse
Weekly newsletter of the UNM Health Sciences Center.
John Proctor Is The Villain Playbill, Providence College Department Of Theatre, Dance, & Film
John Proctor Is The Villain Playbill, Providence College Department Of Theatre, Dance, & Film
Playbill and Promotion
Providence College Department of Theatre, Dance & Film
Angell Blackfriars Theatre
John Proctor is the Villain by Kimberly Belflower
January 30 - February 2, 2025
Director, Noah Putterman
Scenic Design, Samantha Mastrati
Lighting Design, Michael Clark Wonson
Properties Design, Grey Rung
Costume Design, Maxine Wheelock & Christine Britton
Sound Design, Stuart Holland
Choreography, Sarah Putterman
Vocal Coach, Megan Chang
Cast: Raelynn Nix - Olivia Egan; Shelby Holcomb - Isabel Sullivan; Beth Powell - Claire Cunningham; Nell Shaw - Olivia Barbarini; Ivy Watkins - Molly McGoldrick; Mason Adams - Anthony Maldonado; Lee Turner …
January 30, 2025, James Madison University
January 30, 2025, James Madison University
The Breeze, 2020-
The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.
The Impact Of The University Education And Knowledge Transfer Index On The Global Competitiveness Of The United Arab Emirates From The Perspective Of Quality Employees, Dr. Shawk Hasan Mahdi
The Impact Of The University Education And Knowledge Transfer Index On The Global Competitiveness Of The United Arab Emirates From The Perspective Of Quality Employees, Dr. Shawk Hasan Mahdi
Faculty Peer-Reviewed Papers | بحوث هيئة التدريس المحكمة
This study aimed to demonstrate the impact of the university education and knowledge transfer index on the global competitiveness of the United Arab Emirates from the point of view of quality employees. The study relied on the quantitative descriptive survey method. The tool was a questionnaire for data analysis. The study sample consisted of a group that was distributed to a sample of (330) of (director, executive director,
head of department/division, employee) who work in departments, departments, and offices of quality management and academic accreditation in accredited higher education institutions. The sample size was (360) individuals. The sample size was …
Empowering Families To Prevent Violent Extremism, Karyn Sporer
Empowering Families To Prevent Violent Extremism, Karyn Sporer
Reports, Projects, and Research
Families play a critical role in the pathways to radicalization and the prevention of violent extremism. While adverse family conditions — such as abuse, neglect, and parental abandonment — can increase vulnerability to radicalization, strong family bonds and emotional support can help individuals disengage from extremism and reintegrate into society. This study aims to understand the lived experiences of families impacted by violent extremism to identify how they can support prevention efforts. This research was conducted for policymakers, community organizations, and practitioners seeking to develop family-centered strategies to prevent radicalization and support deradicalization. By equipping families with knowledge, resources, and …
The Impact Of Quantitative Platform On Candidacy For Bronchoscopic Lung Volume Reduction: A Multi-Center Retrospective Cohort Study, Max Wayne, Suchitra Pilli, Hee Jae Choi, Nathaniel Moulton, Praveen Chenna, Allen Cole Burks, Alexander Chen
The Impact Of Quantitative Platform On Candidacy For Bronchoscopic Lung Volume Reduction: A Multi-Center Retrospective Cohort Study, Max Wayne, Suchitra Pilli, Hee Jae Choi, Nathaniel Moulton, Praveen Chenna, Allen Cole Burks, Alexander Chen
2020-Current year OA Pubs
BACKGROUND: Bronchoscopic lung volume reduction (BLVR) can be an effective treatment for highly selected patients with severe emphysema but only half of carefully selected patients derive clinical benefit. Two commercially available platforms exist to help determine candidacy for BLVR via quantitative analysis of computed tomography (CT) scans.
OBJECTIVES: To determine if the two commercially available quantitative platforms identified the same patient population that may benefit from BLVR.
DESIGN: A multicenter, retrospective cohort study.
METHODS: Consecutive patients referred for BLVR between January 1, 2022 and March 31, 2023 at three medical centers in the United States with the same CT scan …
Stroma-Derived Dickkopf-1 Contributes To The Suppression Of Nk Cell Cytotoxicity In Breast Cancer, Seunghyun Lee, Biancamaria Ricci, Jennifer Tran, Emily Eul, Jiayu Ye, Qihao Ren, David Clever, Julia Wang, Pamela Wong, Michael S Haas, Sheila A Stewart, Cynthia X Ma, Todd A Fehniger, Roberta Faccio
Stroma-Derived Dickkopf-1 Contributes To The Suppression Of Nk Cell Cytotoxicity In Breast Cancer, Seunghyun Lee, Biancamaria Ricci, Jennifer Tran, Emily Eul, Jiayu Ye, Qihao Ren, David Clever, Julia Wang, Pamela Wong, Michael S Haas, Sheila A Stewart, Cynthia X Ma, Todd A Fehniger, Roberta Faccio
2020-Current year OA Pubs
Mechanisms related to tumor evasion from NK cell-mediated immune surveillance remain enigmatic. Dickkopf-1 (DKK1) is a Wnt/β-catenin inhibitor, whose levels correlate with breast cancer progression. We find DKK1 to be expressed by tumor cells and cancer-associated fibroblasts (CAFs) in patient samples and orthotopic breast tumors, and in bone. By using genetic approaches, we find that bone-derived DKK1 contributes to the systemic DKK1 elevation in tumor-bearing female mice, while CAFs contribute to DKK1 at primary tumor site. Systemic and bone-specific DKK1 targeting reduce tumor growth. Intriguingly, deletion of CAF-derived DKK1 also limits breast cancer progression, without affecting its levels in circulation, …
Emotional Ecosystems: Understanding The Relationship Between Family Interactions And Anxiety Among Cancer Caregivers, Keisha White Makinde, Jacquelyn J Benson, Kyle A Pitzer, Maysara Mitchell, Debra Parker Oliver, George Demiris, Karla T Washington
Emotional Ecosystems: Understanding The Relationship Between Family Interactions And Anxiety Among Cancer Caregivers, Keisha White Makinde, Jacquelyn J Benson, Kyle A Pitzer, Maysara Mitchell, Debra Parker Oliver, George Demiris, Karla T Washington
2020-Current year OA Pubs
OBJECTIVES: Recent studies have challenged the assumption that families are invariable sources of support for cancer caregivers, noting that relationships with family members can have both positive and negative effects on caregiver well-being. This study expands upon prior literature to examine the relationship between cancer caregivers' perceptions of the quality of their family interactions and their symptoms of anxiety.
METHODS: We employed secondary analysis of baseline data from a multisite randomized clinical trial of an intervention for cancer caregivers conducted at 3 large academic palliative care clinics. We performed linear regression analyses to analyze the relationship between caregivers' perceptions of …
One Health Investigation Following A Cluster Of Crimean-Congo Haemorrhagic Fever, North Macedonia, July To November 2023, Dejan Jakimovski, Pavle Banović, Katerina Spasovska, Goran Rangelov, Marija Cvetanovska, Fadil Cana, Verica Simin, Ivana Bogdan, Dragana Mijatović, Aleksandar Cvetkovikj, Igor Djadjovski, Iva Christova, Eleftherios Meletis, Polychronis Kostoulas, Brigitta Zana, Zsófia Lanszki, Tamás Görföl, Zsófia Tauber, Gábor Kemenesi
One Health Investigation Following A Cluster Of Crimean-Congo Haemorrhagic Fever, North Macedonia, July To November 2023, Dejan Jakimovski, Pavle Banović, Katerina Spasovska, Goran Rangelov, Marija Cvetanovska, Fadil Cana, Verica Simin, Ivana Bogdan, Dragana Mijatović, Aleksandar Cvetkovikj, Igor Djadjovski, Iva Christova, Eleftherios Meletis, Polychronis Kostoulas, Brigitta Zana, Zsófia Lanszki, Tamás Görföl, Zsófia Tauber, Gábor Kemenesi
School of Biomedical Sciences
Background: Crimean–Congo haemorrhagic fever(CCHF) is a severe illness characterised by fever,bleeding and high case-fatality rates. The disease iscaused by CCHF virus (CCHFV), transmitted by ticksand infectious body fluids and tissues. Aim: After CCHFwas diagnosed in three persons in 2023, we aimed toinvestigate the presence of antibodies against CCHFVin healthcare workers (HCW), sheep and goats, andof CCHFV in ticks, in an area in North Macedonia andcharacterise virus strains. Methods: In 2023, we collected blood samples from HCWs involved in treating CCHF patients and sera and ticks from sheep andgoats in the village in North Macedonia where theindex case resided. The blood …
Enhancing Immunotherapy Efficacy With Synergistic Low-Dose Radiation In Metastatic Melanoma: Current Insights And Prospects, Zahid Rafiq, Mingyo Kang, Hampartsoum B Barsoumian, Gohar S Manzar, Yun Hu, Ailing Huang, Weiqin Lu, Nahum Puebla-Osorio, James W Welsh
Enhancing Immunotherapy Efficacy With Synergistic Low-Dose Radiation In Metastatic Melanoma: Current Insights And Prospects, Zahid Rafiq, Mingyo Kang, Hampartsoum B Barsoumian, Gohar S Manzar, Yun Hu, Ailing Huang, Weiqin Lu, Nahum Puebla-Osorio, James W Welsh
Faculty, Staff and Student Publications
Recent advances in oncology research have highlighted the promising synergy between low-dose radiation therapy (LDRT) and immunotherapies, with growing evidence highlighting the unique benefits of the combination. LDRT has emerged as a potent tool for stimulating the immune system, triggering systemic antitumor effects by remodeling the tumor microenvironment. Notably, LDRT demonstrates remarkable efficacy even in challenging metastatic sites such as the liver (uveal) and brain (cutaneous), particularly in advanced melanoma stages. The increasing interest in utilizing LDRT for secondary metastatic sites of uveal, mucosal, or cutaneous melanomas underscores its potential efficacy in combination with various immunotherapies. This comprehensive review traverses …
Hypoxia Signaling In The Adipose Tissue
Hypoxia Signaling In The Adipose Tissue
Faculty, Staff and Student Publications
Obesity per se is rapidly emerging all over the planet and further accounts for many other life-threatening conditions, such as diabetes, cardiovascular diseases, and cancers. Decreased oxygen supply or increased relative oxygen consumption in the adipose tissue results in adipose tissue hypoxia, which is a hallmark of obesity. This review aims to provide an up-to-date overview of the hypoxia signaling in the adipose tissue. First, we summarize literature evidence to demonstrate that hypoxia is regularly observed during adipose tissue remodeling in humans and rodent models with obesity. Next, we discuss how hypoxia-inducible factors (HIFs) are regulated and how adipose tissues …