Digital Commons Network^™

Emr-Lip: A Lightweight Framework For Standardizing The Preprocessing Of Longitudinal Irregular Data In Electronic Medical Records, Tingqian Cao, Jin Yin, Jiajun Qiu, Xiaoyan Yang, Yingqiang Guo, Xiaobo Zhou

Faculty, Staff and Student Publications

Objective: Longitudinal data from Electronic Medical Records (EMRs) are increasingly utilized to construct predictive models for various clinical tasks, offering enhanced insights into patient health. However, significant discrepancies exist in preprocessing the irregular and intricate EMR data across studies due to the absence of universally accepted tools and standardization methods. This study introduces the Electronic Medical Record Longitudinal Irregular Data Preprocessing (EMR-LIP) framework, a lightweight approach for optimizing the preprocessing of longitudinal, irregular EMR data, aiming to enhance research efficiency, consistency, reproducibility, and comparability.

Materials and methods: EMR-LIP modularizes the preprocessing of longitudinal irregular EMR data, offering tools with a …

A Statistical Framework Of Watermarks For Large Language Models: Pivot, Detection Efficiency And Optimal Rules, Weijie J Su

Faculty, Staff and Student Publications

Since ChatGPT was introduced in November 2022, embedding (nearly) unnoticeable statistical signals into text generated by large language models (LLMs), also known as watermarking, has been used as a principled approach to provable detection of LLM-generated text from its human-written counterpart. In this paper, we introduce a general and flexible framework for reasoning about the statistical efficiency of watermarks and designing powerful detection rules. Inspired by the hypothesis testing formulation of watermark detection, our framework starts by selecting a pivotal statistic of the text and a secret key-provided by the LLM to the verifier-to control the false positive rate (the …

Evaluating Generalizability Of Oncology Trial Results To Real-World Patients Using Machine Learning-Based Trial Emulations, Ravi B Parikh

Faculty, Staff and Student Publications

Randomized controlled trials (RCTs) evaluating anti-cancer agents often lack generalizability to real-world oncology patients. Although restrictive eligibility criteria contribute to this issue, the role of selection bias related to prognostic risk remains unclear. In this study, we developed TrialTranslator, a framework designed to systematically evaluate the generalizability of RCTs for oncology therapies. Using a nationwide database of electronic health records from Flatiron Health, this framework emulates RCTs across three prognostic phenotypes identified through machine learning models. We applied this approach to 11 landmark RCTs that investigated anti-cancer regimens considered standard of care for the four most prevalent advanced solid malignancies. …

Transcriptome Size Matters For Single-Cell Rna-Seq Normalization And Bulk Deconvolution, Judy Jiaru Wang, Rhea Jain, Jiyang Yu

Faculty, Staff and Student Publications

The variation of transcriptome size across cell types significantly impacts single-cell RNA sequencing (scRNA-seq) data normalization and bulk RNA-seq cellular deconvolution, yet this intrinsic feature is often overlooked. Here we introduce ReDeconv, a computational algorithm that incorporates transcriptome size into scRNA-seq normalization and bulk deconvolution. ReDeconv introduces a scRNA-seq normalization approach, Count based on Linearized Transcriptome Size (CLTS), which corrects differential expressed genes typically misidentified by standard count per 10 K normalization, as confirmed by orthogonal validations. By maintaining transcriptome size variation, CLTS-normalized scRNA-seq enhances the accuracy of bulk deconvolution. Additionally, ReDeconv mitigates gene length effects and models expression variances, …

Law For The Rich, Alex Raskolnikov

Faculty Scholarship

With top incomes and wealth reaching historic highs, scholars and politicians have proposed new taxes and novel legal rules aimed at reversing the emergence of the new Gilded Age. Yet while new taxes target the rich directly by imposing greater burdens only on those with incomes or wealth above multi-million-dollar thresholds, none of the proposed legal reforms do anything of the sort. There appears to be no interest in changing property law, corporate law, antitrust law, or labor law, among others, to have special, more burdensome rules applicable only to the rich. This Article asks: Why not? Why shy away …

Extended State Infrastructure Power In An Age Of Networked Competition: The Cases Of Thailand And Taiwan, Sol Andrew Stokols, Justin Kollar

Research Collection College of Integrative Studies

Scholars have highlighted the emergence of infrastructure as a key domain in the struggle over network centrality in what some call the ‘Second Cold War’ between the U.S. and China. We qualify this ‘infrastructural turn’ by drawing attention to the contingent nature of state infrastructural power as depending on key domestic firms that often serve as intermediaries between domestic infrastructure and global supply chains or international partners. Utilising empirical case studies based on field research conducted between 2021 and 2023 in Thailand and Taiwan, we analyse the ways in which state infrastructure power is exercised through strategic negotiation between national …

Orchestra Librarians’ Responses In The Time Of Covid-19: A Qualitative Study Of Symphony Orchestra Librarians Around The Globe, Patrick Lo, Hermina G.B. Anghelescu

School of Information Sciences Faculty Research Publications

The COVID-19 crisis has disrupted the performing arts ecosystem worldwide, with an even more severe impact on classical orchestras. This study examines how 19 seasoned, established orchestra librarians and their parent organizations worldwide experienced and responded to the COVID-19 pandemic. The study examines similarities and differences in their professional practices and experiences of coping with pandemic-related disruptions. The study sheds new light on how orchestra librarians' practices changed, along with their resilience, adaptability, sense of self-worth, and career fulfilment during COVID-19,in the context that none were furloughed or made redundant. The paper also discusses the impact of pandemic restrictions on …

A Pragmatic Legacy: Charles Wilson’S Politics And The Battle For His Archival Heritage, Jordan Coleman

Electronic Theses and Dissertations

Congressman Charlie Wilson served Texas and the United States with distinction throughout his political career, leaving a profound impact on East Texas and the global stage. Known for his progressive policies in the Texas Legislature and his influential role in U.S. foreign policy during his tenure in Congress, Wilson’s pragmatic political career and legacy is preserved in the Charlie Wilson Congressional Papers collection at the East Texas Research Center (ETRC). Despite its historical significance, the collection faced decades of delayed processing, disorganization, and neglect of archival best practices. This public history thesis confronts these challenges by detailing the efforts to …

Stealth Navigation With Ifuse-Torq Implant For Sacroiliac Joint Fusion Technique Guide., Jia Bao Lin, Bryan L Demyan, Logan M Bushnell, Morgan T Turnow, Benjamin C Taylor

Surgery Articles

INTRODUCTION: Dysfunction of the sacroiliac (SI) joint exists in nearly one-third of patients with lower back pain. There are nuances in diagnosing SI joint dysfunction with a combination of physical exam maneuvers and intra-articular injections. The management of patients with SI joint pain can include posterior pelvic fixation, which traditionally has been described using fluoroscopy to obtain safe placement of implants.

CASE REPORT: In this technique guide, we would like to introduce a novel technique of using Stealth navigation to facilitate SI fusion with the iFuse-TORQ implant.

CONCLUSION: SI dysfunction is a common cause of low back pain that can …

The Role Of Adjunctive Medial Plating In Distal Femur Fractures And Distal Femur Fractures Nonunions., Jerrod Steimle, Jaron L Lohmeyer, Benjamin Taylor, Daniel T Degenova

Trauma and Acute Care Articles

PURPOSE: There exists controversy in the treatment of acute distal femur fractures as well as distal femur fracture nonunions. The objective of this study is to determine the clinical benefit of adjunctive medial plate application in the setting of acute distal femur fractures and distal femur fracture nonunions.

METHODS: This is a retrospective comparative study at a Level 1 academic trauma center, including 104 patients treated for acute distal femur fractures and 23 patients treated for distal femur nonunions between 2015 and 2019. The study compared dual plate fixation to other methods of fixation.

RESULTS: In the acute fracture setting, …

Augustine’S Response To The Problem Of Evil, Matthew Dawson

Father Jack McGrath, S.M., Research Award Presentations

Matthew Dawson is a recipient of the Father Jack McGrath, S.M., Award for Research in Catholic Intellectual Traditions.

Jane Goodall’S Integration Of Science And Spirituality, Estella Elpers

Father Jack McGrath, S.M., Research Award Presentations

Estella Elpers is a recipient of the Father Jack McGrath, S.M., Award for Research in Catholic Intellectual Traditions.

Police Sexual Violence As Psychological Detention: Making Full Use Of Charter Rights, Sandrine Ampleman-Tremblay

Dalhousie Law Journal

This paper argues that individual responsibility has been overemphasized in cases of sexual violence by police. The fact that police officers are part of a state system calls for an examination of the role of the state in contributing to the risks of sexual violence by police. The paper thus contends that Canadian law requires methods to address state blame in such cases. It analyses psychological detention under section 9 of the Canadian Charter of Rights and Freedoms as a means to draw a connection between police powers, sexual violence, and state blame. The suggested section 9 interpretation builds on …

Application Of Convolutional Neural Network For Seismic Event Classification: Impact Of Dataset Quality, Distribution, And Human-In-The-Loop Feedback, Yanwei Zhang, Stephen S. Gao, Xiaoyi Fan, Shaohui Zhou, Junhao Qu

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Convolutional neural networks (CNNs) have gained popularity in geophysical research due to their exceptional performance in various areas. However, achieving reliable results with CNNs typically requires a significant amount of high-quality data for training. In this study, we develop a CNN to classify natural earthquakes, mine collapses, and explosions using seismic waveforms from 287 stations in Shandong Province, China. The dataset comprises 1035 earthquakes, 159 mine collapses, and 586 explosions. To address the impact of unreliable measurements, we employ cross validation to screen, manually correct, or discard measurements with inconsistent labels assigned by human experts and CNN. By refining the …

Influence Of Temperature, Oxygen Partial Pressure, And Microstructure On The High-Temperature Oxidation Behavior Of The Sic Layer Of Triso Particles, Visharad Jalan, Adam Bratten, Meng Shi, Tyler Gerczak, Haiyan Zhao, Jonathan D. Poplawsky, Xiaoqing He, Grant Helmreich, Haiming Wen

Materials Science and Engineering Faculty Research & Creative Works

Tri structural isotropic (TRISO)-coated fuel particles are designed for use in high-temperature gas-cooled nuclear reactors, featuring a structural SiC layer that may be exposed to oxygen-rich environments over 1000 °C. Surrogate TRISO particles were tested in 0.2–20 kPa O2 atmospheres to observe the differences in oxidation behavior. Oxide growth mechanisms remained consistent from 1200–1600 °C for each PO2, with activation energies of 228 ± 7 kJ/mol for 20 kPa O2 and 188 ± 8 kJ/mol for 0.2 kPa O2. At 1600 °C, kinetic analysis revealed a change in oxide growth mechanisms between 0.2 and 6 kPa O2. In 0.2 kPa …

Elevated Temperature Performance: Arc-Jet Testing Of Carbon Fiber Reinforced Zrb2 Bars Up To 2200 °C For Strength Retention Assessment, D. Sciti, A. Vinci, L. Zoli, P. Galizia, M. Mor, W. Fahrenholtz, S. Mungiguerra, R. Savino, A. M. Caporale, A. Airoldi

Materials Science and Engineering Faculty Research & Creative Works

For the first time, ultra-high temperature ceramic matrix composite bars were tested inside an arc-jet facility to investigate the impact of oxidation damage on strength retention. The composite bars, which were based on a ZrB2 / SiC matrix reinforced with 45 vol% carbon fibers, were produced by slurry impregnation and sintering. The first batch was tested under 3-point (pt) bending, and two additional batches were exposed to plasma of dissociated air up to a temperature of 2200 °C for 2 min or 2.2 min and then subjected to 3-pt bending. More than 75% of the initial strength was retained even …

Incorporating Pediatrics In Clinical Education: A Call To Action In Inpatient Pharmacy Practice., Caroline M Sierra, Amanda C Capino, Cober M Petrea, Lea S Eiland, Norm Fenn Bcps, Bcpps, Nicholas M Fusco, Lucas E Orth

Parkview Pharmacy Department

Background

The recently revised 2025 Accreditation Council for Pharmacy Education (ACPE) Standards state the expectations of Advanced Pharmacy Practice Experiences (APPEs) are to “emphasize continuity of care and incorporate acute, chronic, and wellness-promoting patient-care services…[and] expose students to diverse patient populations as related to age, sex race/ethnicity, socioeconomic factors…and disease states.”1 These expectations describe the conditions under which student pharmacists are expected to develop and demonstrate competence in the entrustable professional activities (EPAs), which were revised in 2022 to more accurately reflect current pharmacy practice.2 However, the definition of required APPE (Standard 3.2.d.) states that the inpatient patient …

Establishment Of The Nichols Strain As The Type Strain Of Treponema Pallidum, Steven J Norris

Faculty, Staff and Student Publications

In this article, it is proposed that the Nichols strain of Treponema pallidum be established as the type strain. T. pallidum was first identified as the causative agent of syphilis in 1905, and the Nichols strain was isolated in 1912 by inoculation of a rabbit with cerebrospinal fluid from a patient with neurosyphilis. The Nichols strain has been maintained by serial passage in rabbits for over a century, and historically most studies of T. pallidum have been conducted using this strain. In recent years, a procedure for continuous in vitro culture of T. pallidum in a tissue culture system has …

Looking Out For Danger: Theoretical And Empirical Issues In Translating Human Attention Bias Tasks To Assess Animal Affective States, Sarah Kappel, Sarah Collins, Michael Mendl, Carole Fureix

School of Biological and Marine Sciences

Understanding animal emotional (affective) state is highly relevant to various disciplines (e.g., animal welfare, neuroscience, comparative psychology), and has been significantly advanced by translating affect-induced cognitive bias paradigms rooted in human psychology to non-human animal studies. Attention bias (i.e., preferential attention allocation, AB) tests are increasingly used as more practical substitutes to commonly used judgement bias tests. Yet, evidence that AB reflects affective valence in animals is still limited. We review in-depth the concept of attention and AB described in humans and discuss utilising human-derived AB paradigms for measuring animal affective states. We describe key concepts and functions of attention …

Table Of Contents - Cardozo Law Review, Volume 46, Issue 3

Cardozo Law Review

No abstract provided.

Buyer, Beware Of Addiction, Erin E. Meyers, Clayton J. Masterman

Cardozo Law Review

Addictive products kill more than 700,000 people in the United States every year. Despite the large-scale risks that addiction poses, the law requires manufacturers of addictive products to disclose little-to-no information about the risk of addiction—the single most consequential characteristic of a class of products contributing to mass death every year.

While consumers understand that addictive products are, in fact, addictive, they generally do not understand the magnitude of the addiction risks that they face. Metaphorically, consumers understand that they are playing a game of “Russian roulette” when they consume an addictive product—but they play without knowing how many bullets …

The End Of Fda Exceptionalism? Dissecting Deference To The Fda In Drug Disputes, Anjali Deshmukh

Cardozo Law Review

On April 7, 2023, a federal judge issued a nationwide stay on the United States Food and Drug Administration (FDA) approval of the abortifacient medication mifepristone. It was instantly a landmark case, decried as the first time in over one-hundred years that a federal court nullified an FDA drug approval. A few hours later, a second federal district court enjoined FDA restrictions on mifepristone. Two federal courts substantively evaluating FDA drug approval data in one day is unprecedented. It begs the question: will courts overturn FDA drug approvals again?

Conventional wisdom says no. Abortion exceptionalism, the trend of legislatures and …

Revisiting Reasonable Cybersecurity, Jeffrey L. Vagle

Cardozo Law Review

Prospective theories of cybersecurity liability have traveled over some well-worn paths over the past three decades, resulting in some successes, but also in at least as many cul-de-sacs and dead ends. Part of this problem can be found in the difficulty and complexity of the subject itself. Courts, legislators, and regulators all face comprehension difficulties when they attempt to fit our existing legal system around cybersecurity, often resulting in half-measures and generalized solutions that are challenging to apply to the widely different technical details behind each case. And in the background, we have a general reluctance to create legal regimes …

Leveling The Playing Field: Aligning Title Ix And Title Vii Sexual Harassment Standards To Ensure Equity For Female Hazing Victims, Cammie Swain

Cardozo Law Review

As hazing has become more common among student-athletes at colleges and universities throughout the country, litigants have used Title IX as a legal remedy to hold these educational institutions accountable for hazing practices on their campuses. However, while various male plaintiffs have brought successful Title IX cases alleging that their hazing experiences constitute actionable discrimination under Title IX, fewer women have had success in bringing such cases. This disparity looms especially large as the number of hazing incidents among women has grown and as intercollegiate athletics has transformed into a massive, lucrative industry. Since 2021, student-athletes have been able to …

Reforming The Rules: A Proposal For Modifying The Model Rules Of Professional Conduct To Permit Partnerships Between Lawyers And Nonlawyers In The Practice Of Law, Sholom Zeitlin

Cardozo Law Review

The Model Rules of Professional Conduct prohibit partnerships between lawyers and nonlawyers in the practice of law, a ban that purportedly exists to protect lawyers’ professional independence of judgment. Despite this noble sentiment, the prohibition ultimately hurts the legal market, to the expense of potential clients, by limiting the professional options available at the lawyer’s disposal. The existence of lawyer-nonlawyer partnerships, recently espoused by two states, both decreases the costs and barriers involved in obtaining justice and encourages much-needed legal innovation. While other scholars have proposed schemes that would permit such partnerships without compromising the lawyer’s professional responsibility, their methods …

Coevolution Of Soes And The Chinese Economy: The Roles Of Soe Heterogeneity From The Institutional, Strategic, And Organizational Perspectives, Kenneth G. Huang, Runtian Jing, Jun Xia, Man Zhang, Weiguo Zhong, David Zhu

Research Collection Lee Kong Chian School Of Business

State-owned enterprises (SOEs) in China play a critical role in national economic development and the country's positioning on the global stage. Chinese SOEs have undergone substantial transformations from traditional government-run entities to a variety of corporate forms exhibiting different levels of state involvement. Despite their substantial influence, the internal diversity of SOEs – from wholly state-owned to mixed-ownership – has not been thoroughly examined. This paper provides an overview of SOEs' critical roles in the Chinese economy, the relationship between SOEs and privately owned enterprises (POEs), and the challenges of SOEs in different stages of Chinese economic development. It then …

Covid-19- In Children Evidence For Treatment With Remdesivir, Children's Mercy Kansas City

Clinical Critically Appraised Topics

No abstract provided.

Critical Picture Book Literacy, Caitlin Stewart, Heather Koopmans

Faculty and Staff Publications – Milner Library

This study sought to revisit established definitions of critical visual literacy and determine how this concept could be re-envisioned specifically for picture books when informed by the approaches of teacher education students who had received limited prior formal instruction on critiquing visual texts. Seventeen sophomore elementary education students engaged in written self-discourse around the visual narrative of Milo Imagines the World written by Matt de la Peña and illustrated by Christian Robinson where they generated questions and answers critically engaging with the visuals. These participants’ responses underwent thematic analysis informed by grounded theory which uncovered a collective definition for critical …

Evaluating The Ghg Emissions, Land Use, And Water Use Associated With Contemporary Dietary Patterns In The Republic Of Ireland, Daniel Burke, Paul Hynds, Anushree Priyadarshini

Articles

Dietary patterns are intrinsically linked to greenhouse (GHG) emissions, land use, and water use via food production systems. Analysing and comparing contemporary dietary patterns and their environmental impact is critical to identifying which should be promoted to enhance global sustainability. A cross-sectional survey of adult consumption patterns was conducted across Ireland with a representative sample size of 957 respondents. Subsequently, a farm-to-fork life cycle assessment (LCA) was employed via OpenLCA 2.0.4 to assess three primary environmental impacts (global warming, land use, and water use) across the population. Thirteen distinct dietary patterns were analysed: total population, rural, urban, self-reported (omnivore, flexitarian, …

Impurity Behavior In Cast Copper Anodes: Implications For Electrorefining In A Circular Economy, Agustin Morales-Aragon, Daniel Sánchez-Rodas, Guillermo Ríos, Michael S. Moats

Materials Science and Engineering Faculty Research & Creative Works

The behavior of impurities in cast copper was investigated to simulate production with increased utilization of secondary sources within the framework of a circular economy. The incorporation of impurities, particularly Ni, Sn, and Sb, from recycled Cu may significantly impact the electrorefining process. In this study, commercial anodes were doped with Ni, Sn, and Sb concentrations of 2500–6500 g/t, 300–900 g/t, and 450–950 g/t, respectively. Anode concentrations of Pb and Bi were maintained at 1000 g/t and 350 g/t, respectively. As concentrations were examined at two levels, 860 or 1700 g/t, depending on the commercial anode used to create the …