Digital Commons Network^™

Differences In Outcomes For Patients Receiving Labetalol And Nicardipine For Hypertension After Craniotomy, Matthew Owrey, George Sun, Kevin J. Min

Department of Anesthesiology Faculty Papers

Background: Acute postoperative hypertension is commonly encountered in patients following craniotomy and is associated with major complications. The purpose of this retrospective cohort study was to evaluate 30-day survival for patients who received labetalol, nicardipine, or both for hypertension after craniotomy.

Methods: Patients 18 and older who underwent craniotomy between January 1, 2010 and January 1, 2023 were included in the study. Three separate analyses were performed comparing each group: 1) labetalol cohort versus nicardipine cohort, 2) labetalol cohort versus both cohort, and 3) nicardipine cohort versus both cohort. The primary outcome was survival at 30 days. Secondary outcomes included …

Against Moralizing Nature: Latin American Romanticism And The Aporias Of The Ecocritical Turn, Claudio Aguayo-Borquez

Modern Languages Faculty Publications

This article argues that the ecocritical turn in literary criticism reproduces the dualisms it seeks to avoid, especially the contradiction between nature and culture. At the same time, ecocriticism risks the veneration of Nature already practiced and promoted within the Romantic tradition in the global epoch of primitive accumulation during the 19th century. To sustain this argument, this article follows three main steps. In the first place, it establishes a characterization of Romanticism's attitude towards Nature, defining it as the literaturization of Nature, following Abrams' notion of supernatural naturalism and Jean Luc-Nancy and Philippe Lacoue-Labarthe's definition of Romanticism as the …

Advances In Machine Learning For Pain Recognition: A Review Of Algorithms, Modalities, And Outcomes, Abdulrahman Alsharif

Theses

The emergence of machine learning (ML) in healthcare has unlocked the transformative potential of pain detection and assessment. By providing new ways to address the challenges associated with subjective and inconsistent pain assessment methods. This review synthesizes recent advancements in ML-based approaches for pain detection, focusing on algorithms, modalities, and datasets. Techniques such as neural networks, transformer models, and multimodal fusion frameworks have demonstrated significant promise in identifying pain from diverse sources, including facial expressions, physiological signals, and synthetic datasets. Key contributions include novel transformer-based architectres like PainAttnNet for analyzing electrodermal activity [1], multimodal datasets such as BioVid for advancing …

Yinyang-Align: Benchmarking Contradictory Objectives And Proposing Multi-Objective Optimization Based Dpo For Text-To-Image Alignment, Amitava Das, Yaswanth Narsupalli, Gurpreet Singh, Vinija Jain, Vasu Sharma, Suranjana Trivedi, Aman Chadha, Amit Sheth

Publications

As Text-to-Image (T2I) models become more advanced, they face a fundamental challenge—balancing conflicting alignment goals such as faithfulness vs. artistic freedom, realism vs. stylization, and verifiability vs. creativity. Existing alignment methods often optimize for one objective at the cost of another, leading to inconsistencies in AI-generated images.
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/="/">In our latest work, YinYang-Align, we introduce a benchmarking framework to systematically evaluate these trade-offs and propose Contradictory Alignment Optimization (CAO)—a multi-objective extension of Direct Preference Optimization (DPO) that enables models to navigate competing alignment goals more effectively.

The International Law Commission's Seventy-Fifth (2024) Session: Immunity Of State Officials From Foreign Criminal Jurisdiction And Other Topics, Charles C. Jalloh

Articles

The International Law Commission (Commission or ILC) held its seventy-fifth session at its seat in Geneva from April 15 to May 31 and from July 1 to August 2, 2024. The Commission was chaired by Mr. Marcelo Vázquez-Bermúdez (Ecuador), and for the first time since its establishment in 1945, elected a majority of three females out of the five officers elected to its bureau annually. The Commission celebrated its seventy-fifth anniversary and progressed its work on the topics in the program of work despite the shortening of the twelve-week General Assembly approved session to ten weeks due to the liquidity …

Marginalized, Secularized, And Popularized? The Prevalence And Patterns Of Paranormal Belief In The United Kingdom, Tom Clark, Joseph O. Baker, Christoper D. Bader

Sociology Faculty Articles and Research

There is growing recognition of the prevalence of paranormal beliefs in Western countries. However, most of this interest has been focused on the United States and robust, comparative data remain limited. This study extends this literature to report findings from a national survey of the United Kingdom designed to assess the prevalence and patterns of paranormal beliefs. Although there are many similarities to previous research, the results also suggest that there are significant differences in the scope, clustering, and patterns of paranormalism across contexts. The study makes four contributions to research on the paranormal by a) reiterating the continuing popularity …

Mac Brandt, Double Bass, February 10, 2025 [Program], University Of Northern Iowa. School Of Music.

Music Recital Programs

Program of a music recitals given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.

Ndls Communicator: Week Of 02.10.25, Notre Dame Law School

NDLS Communicator

The Latest News

• Galilee Immersion Program: Exposing first-year law students to the impact of public interest law
• Dennis Wieboldt exemplifies success in Notre Dame Law School's dual degree program

Faculty News and Briefs

• Mary Ellen O'Connell appeared on DW News, where she spoke about President Trump's remarks about potential U.S. involvement in Gaza.
• Sam Bray was mentioned in a Daily Caller article about recent legal injunctions as a result of Trump administration executive orders.
• Rick Garnett was quoted about the meaning of separation of church and state in an NCR article about the St. Isidore of Seville Catholic Virtual School …

Sex And Outcomes Of Patients With Microsatellite Instability-High And Braf V600e Mutated Metastatic Colorectal Cancer Receiving Immune Checkpoint Inhibitors, Vincenzo Nasca, Joseph Zhao, Javier Ros, Sara Lonardi, Koen Zwart, Marwan Fakih, Jeanine M L Roodhart, Jeroen Derksen, Rossana Intini, Francesca Bergamo, Giacomo Mazzoli, Filippo Ghelardi, Marta Ligero, Jitendra Jonnagaddala, Nicholas Hawkins, Robyn L Ward, Durgesh Wankhede, Hermann Brenner, Michael Hoffmeister, Marco Vitellaro, Lisa Salvatore, Claire Gallois, Pierre Laurent-Puig, Chiara Cremolini, Michael J Overman, Julien Taieb, David Tougeron, Thierry Andre, Jakob Nikolas Kather, Raghav Sundar, Javier Carmona, Elena Elez, Miriam Koopman, Filippo Pietrantonio

Faculty, Staff and Student Publications

Background: Immune checkpoint inhibitors (ICIs) are the gold standard therapy in patients with deficient mismatch repair (dMMR)/microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC). A significant proportion of patients show resistance, making the identification of determinants of response crucial. Growing evidence supports the role of sex in determining susceptibility to anticancer therapies, but data is lacking for patients with MSI-H CRC.

Methods: In this real-world cohort comprising 624 patients with MSI-H mCRC receiving ICIs, we investigated the impact of sex on patients' outcomes, overall and according to RAS-BRAF mutational status or type of treatment (anti-PD-(L)1 with or without anti-CTLA-4 agents). We …

Tigit Inhibitor M6223 As Monotherapy Or In Combination With Bintrafusp Alfa In Patients With Advanced Solid Tumors: A First-In-Human, Phase 1, Dose-Escalation Trial, Aung Naing, Meredith Mckean, Anthony Tolcher, Anja Victor, Ping Hu, Marco A F Nogueira Filho, Stephan Gleicher, Daniel Holland, Emilia Richter, Keyvan Tadjalli-Mehr, Lillian L Siu

Faculty, Staff and Student Publications

Background: M6223 is an intravenous (IV), Fc-competent, fully human, antagonistic, anti-T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domains (TIGIT) antibody. Bintrafusp alfa (BA) is a bifunctional fusion protein that simultaneously blocks nonredundant immunosuppressive TGF-β and PD-(L)1 pathways.

Methods: This first-in-human, dose-escalation study in patients with advanced solid tumors (N=58; aged ≥18 years, ECOG PS≤1) evaluated M6223 alone (Part 1A, n=40; M6223 10-2400 mg every 2 weeks, n=32; M6223 2400 mg every 3 weeks, n=8) or with BA (Part 1B, n=18; M6223 300-1600 mg with BA 1200 mg; both every 2 weeks, intravenous). Primary objectives were safety, tolerability, …

Verbal And Numeric Eyewitness Confidence Differentially Affect Decision-Making, Pia Pennekamp

Psychological Science Faculty Publications and Presentations

Eyewitness confidence is typically communicated verbally (e.g., certain). Interpretations for verbal confidence statements are variable which could affect decision-making. I explored the extent to which confidence format (i.e., verbal vs. numeric) influences juror decision-making. Participants (N = 468) read a trial vignette in which an expert witness draws attention to the eyewitness's confidence in their suspect identification (uncertain, or certain, or 28%, or 88%). Participants rated the expert's recommendation, rendered a conviction decision, and provided confidence in their decision on a scale of 0 = Not at all confident to 10 = Completely confident. Mock-jurors were more likely to convict …

Classification Of Non-Tcga Cancer Samples To Tcga Molecular Subtypes Using Compact Feature Sets, Kyle Ellrott, Christopher K Wong, Christina Yau, Mauro A A Castro, Jordan A Lee, Jasleen K Grewal, Bahar Tercan, Verena Friedl, Toshinori Hinoue, Vladislav Uzunangelov, Lindsay Westlake, Xavier Loinaz, Ina Felau, Peggy I Wang, Anab Kemal, Samantha J Caesar-Johnson, Ilya Shmulevich, Alexander J Lazar, Ioannis Tsamardinos, Katherine A Hoadley, Cancer Genome Atlas Analysis Network, A Gordon Robertson, Theo A Knijnenburg, Christopher C Benz, Joshua M Stuart, Jean C Zenklusen, Andrew D Cherniack, Peter W Laird

Faculty, Staff and Student Publications

Molecular subtypes, such as defined by The Cancer Genome Atlas (TCGA), delineate a cancer's underlying biology, bringing hope to inform a patient's prognosis and treatment plan. However, most approaches used in the discovery of subtypes are not suitable for assigning subtype labels to new cancer specimens from other studies or clinical trials. Here, we address this barrier by applying five different machine learning approaches to multi-omic data from 8,791 TCGA tumor samples comprising 106 subtypes from 26 different cancer cohorts to build models based upon small numbers of features that can classify new samples into previously defined TCGA molecular subtypes-a …

The Relationship Between Anthropometric Sizing, Fit Issues, And Return Rates In Plus-Size Women's Apparel, Cassondra Smith

Walden Dissertations and Doctoral Studies

Retail business owners remain concerned with apparel sizing and return sales, as sizing is a frequent predictor of apparel returns and decreased revenue. Grounded in new product development theory (NPD), the purpose of this quantitative correlational study was to examine the relationship between anthropometric apparel sizing standards, sizing and fit issues, and return sales. The participants were 89 women’s bridal apparel owners and leaders within the retail business sector who completed a 5-point Likert-type survey. The results of the multiple linear regression were significant, 3, 85) = 32.301, p < .001, R2 = .533. In the final model, there were two predictors which were significant, sizing and fit (t = 9.718, p = <.001, ß = .735) and sizing standards (t = 2.478, p = .01, ß = .205). A key recommendation is for retail business leaders to acknowledge the growth in the U.S. female apparel consumer. Further, the alignment of sizing standards and product offerings provides functional apparel and mitigates return sales due to sizing. The implications for positive social change include the potential for the apparel industry to acknowledge the growing complexity of women’s sizing, which is influenced by diverse cultural backgrounds and body types. This shift could promote greater inclusivity, enhance consumer confidence, reduce return rates, and foster broader acceptance of diverse female body types within the industry.

The Lived Experiences Of Prediabetes And Type 2 Diabetes Among African Americans In Rural West Virginia, Orlando Craighead

Walden Dissertations and Doctoral Studies

African Americans in rural Appalachian West Virginia experience disproportionate rates of diabetes, with limited research examining their unique challenges in managing this chronic condition. This qualitative study aimed to explore how African Americans in rural Appalachia develop and utilize diabetes management skills, examining the intersections of cultural influence, healthcare access, and technological adoption. Using a hermeneutic phenomenological approach grounded in the Social Determinants of Health theory, Health Belief Model, and Social Ecological Model, semi-structured interviews were conducted with nine African American adults diagnosed with pre-diabetes or Type 2 diabetes in Kanawha County. Thematic analysis revealed four main themes: Cultural and …

An Educational Intervention Focused On The Care Of Older Adults, Michele Orzehoski

Walden Dissertations and Doctoral Studies

It is estimated that by 2050, individuals ages 65 and older will comprise 20% of the U.S. population. Further, research has demonstrated that among these aging adults, 80% have one chronic condition with 77% having at least two chronic conditions. Given this, the Institute for Healthcare Improvement (IHI) developed the Age-Friendly Health System framework for the care of older adults centering on what matters, medication, mentation, and mobility, or the 4Ms. In the local organization, leadership determined there was a need for an older adult-centered care model given their population includes aging individuals. Thus, the purpose of this doctor of …

Social Media Influence On African American Women Mental Health And Self-Image, Terressa Sanchez Gamble

Walden Dissertations and Doctoral Studies

African American women’s perspectives on the influence of social media content on their mental health (i.e., moods, thoughts, and behaviors) and self-image were explored in this qualitative study. The theoretical framework chosen for this study was Festinger’s (1954) social comparison theory, which was used to examine whether there was a logical connection between the study topic and the framework presented. Data were collected through semistructured interviews that were conducted via Zoom. The data from 10 participants’ interviews were transcribed and analyzed using a thematic analysis approach, resulting in the following two emergent themes: (a) pressure to compare and emulate and …

The Perceptions Of Nursing Faculty Who Experience Student Incivility Behavior, Dehlia Abaya Parsons

Walden Dissertations and Doctoral Studies

Incivility among nursing students is well documented in the academic, clinical, and leadership literature. Student incivility towards faculty was less studied, and merited investigation because incivility can lead to faculty discontentment, stress, and attrition, exacerbating the scarcity of nursing faculty. The purpose of this qualitative phenomenological study, which was underpinned by the health belief model, was to explore the perceptions of nursing faculty who experience student incivility in the Western region of the United States. Open-ended, semistructured interviews were conducted with 11 nursing faculty who shared perceptions of their experience of student incivility behavior. Open coding and thematic analysis yielded …

The Relationship Between Percentage Of Layoffs, Company Age, And Earnings Per Share In Tech Firms, Demarco Dejion Pope

Walden Dissertations and Doctoral Studies

Business owners and investors are concerned that layoff announcements and company age may negatively impact earnings per share (EPS), reducing investor confidence and ultimately lowering stock performance. This decline in stock value can affect a company’s ability to attract investment and sustain long-term growth. Grounded in the prospect theory, the purpose of this quantitative correlational study was to examine the relationship between the percentage of layoffs, company age, and earnings per share. The participants were 107 technology firms with at least 1,000 employees on the NASDAQ Stock Index that initiated layoffs during the 2021–2022 calendar years. The data was collected …

Executive Leadership Practice Through The Lens Of Religiosity And Ethics, Christopherlie Roger

Walden Dissertations and Doctoral Studies

The specific research problem addressed through this study is executive leadership religiosity and decision-making that leads to unethical behaviors and practices that could result in corporate corruption at Fortune 500 companies in the United States region of New York State. The purpose of this qualitative multiple case study research was to explore executive leadership religiosity and decision-making through three research questions, for example, how executive leadership perceives unethical leaders' behaviors and practices that could result in corporation corruption. This study's conceptual foundation and key concepts included religiosity, ethics, decision-making, and the theory of planned behavior. The participants comprised nine executive …

A Critical Appraisal Of Poverty In The Context Of Nature-Based Communities: Selected Cases From The Philippines, Carla Edith Gonzales Jimena

Dissertations and Theses

The Philippines is considered one of the wealthiest countries in both Southeast Asia and the world when measured by biodiversity, mineral resources and natural resources. It is also one of the most highly mineralized countries on earth. However, despite these natural endowments, when measured by established economic and human development indices the Philippines remains poor. Using critical perspectives derived from Marxist tradition, William Chambliss' theory of law and its dialectical nature, Immanuel Wallerstein's World Systems Theory, and Fred Block's structural mechanism of the state, this study aimed to critically appraise the persistence of poverty in nature-based communities in the Philippines. …

Black Online College Students' Perceptions Of Their Unmet Needs During Covid-19, Zanita Gaither

Walden Dissertations and Doctoral Studies

Black college students face unique challenges in achieving academic success, particularly when their unmet needs are not addressed adequately. The COVID-19 pandemic worsened these challenges for online learners in this group, impacting motivation and learning experiences. This interpretive phenomenological analysis explored the lived experiences of Black online college students and their perceptions of unmet needs during the pandemic. Despite numerous studies on Black college students during the pandemic, little literature has been focused on their perceptions of unmet needs. To understand their needs and experiences, this study considered internal and external influences based on Maslow’s hierarchy of needs and Rovai’s …

Stories Of Pastors' Wives, Their Responsibilities, And Their Mental Health, Marsha Patrice Wilson

Walden Dissertations and Doctoral Studies

Church ministry has many written and unwritten rules, responsibilities, and expectations for those who choose to serve in pastoral roles. Some responsibilities and expectations cause church pastors to experience stress and burnout, which has residual effects on their wives and families. Many church leaders or congregations are not aware of or consider the emotional impact of unwritten rules and expectations on the pastors’ wives. The purpose of this narrative research was to explore the stories of Protestant church pastors’ wives and highlight how their various supportive roles in marriage and ministry impacts their emotional and mental health. With a feminist …

Violence Among Nigeria’S Female And Predictors Of Help-Seeking Behavior Using Technology, Abayomi Karunwi

Walden Dissertations and Doctoral Studies

The decision-making autonomy of female intimate partner violence (IPV) survivors to make financial transactions is a stronger predictor of help-seeking behavior that is not yet fully explored. Despite the plausibility of using the mobile phone for financial transactions, it is yet to be explored as a predictor of help-seeking behavior after IPV events through digital financial inclusion. The dataset from the 2018 Nigerian Demographic Health Survey was used to explore if digital financial inclusion could predict help-seeking behavior instead of the severity of abuse among ever-partnered Nigerian female IPV survivors (aged 15 to 49 years) who use their mobile phones …

Contrast-Enhanced Magnetic Resonance Imaging Based Calf Muscle Perfusion And Machine Learning In Peripheral Artery Disease, Addison A Taylor, Jean Bismuth, Dipan J Shah, Gerd Brunner

Faculty, Staff and Students Publications

Peripheral artery disease (PAD) remains underdiagnosed and undertreated and is associated with an increased risk for adverse cardiovascular outcomes. Imaging provides an approach to identifying patients with PAD. However, the role of integrating imaging with machine learning to identify PAD patients and potentially assess disease severity remains understudied. A total of 56 participants, including 36 PAD patients with intermittent claudication and 20 matched controls, underwent contrast-enhanced magnetic resonance imaging (CE-MRI) calf muscle perfusion scanning. CE-MRI-derived dynamic muscle perfusion maps were developed to quantify alterations of the microvascular circulation in the calf muscles based on voxel contrast enhancement. These dynamic muscle …

Long-Read Sequencing Of 945 Han Individuals Identifies Structural Variants Associated With Phenotypic Diversity And Disease Susceptibility, Yanhui Zhao, Yechao Huang, Qinsheng Chen, Hui Qiao, Yang Gao, Jialin Zhao, Yunchao Ling, Ruifang Cao, Jingze Tan, Qi Wang, Yanyun Ma, Jing Li, Jingchun Luo, Sijia Wang, Jiucun Wang, Guoqing Zhang, Shuhua Xu, Feng Qian, Fang Zhou, Huiru Tang, Dali Li, Chinese Pangenome Consortium (Cpc), Fritz J Sedlazeck, Li Jin, Yuting Guan, Shaohua Fan

Faculty, Staff and Students Publications

Genomic structural variants (SVs) are a major source of genetic diversity in humans. Here, through long-read sequencing of 945 Han Chinese genomes, we identify 111,288 SVs, including 24.56% unreported variants, many with predicted functional importance. By integrating human population-level phenotypic and multi-omics data as well as two humanized mouse models, we demonstrate the causal roles of two SVs: one SV that emerges at the common ancestor of modern humans, Neanderthals, and Denisovans in GSDMD for bone mineral density and one modern-human-specific SV in WWP2 impacting height, weight, fat, craniofacial phenotypes and immunity. Our results suggest that the GSDMD SV could …

Cimpact-Now Update 8: Clarifications On Molecular Risk Parameters And Recommendations For Who Grading Of Meningiomas, Felix Sahm, Sonika Dahiya, Et Al.

2020-Current year OA Pubs

Meningiomas are the most frequent primary intracranial tumors. Hence, they constitute a major share of diagnostic specimens in neuropathology practice. The 2021 WHO Classification of Central Nervous System Tumors ("CNS5") has introduced the first molecular grading parameters for meningioma with oncogenic variants in the TERT promoter and homozygous deletion of CDKN2A/B as markers for CNS WHO grade 3. However, after the publication of the new classification volume, clarifications were requested, not only on novel but also on long-standing questions in meningioma grading that were beyond the scope of the WHO "blue book." In addition, more recent research into possible new …

Lifespan In Rodents With Myt1l Heterozygous Mutation, Allyson Schreiber, Raylynn G Swift, Leslie Wilson, Kristen L Kroll, Joseph D Dougherty, Susan E Maloney

2020-Current year OA Pubs

MYT1L syndrome is a newly recognized disorder characterized by intellectual disability, speech and motor delay, neuroendocrine disruptions, ADHD, and autism. In order to study this gene and its association with these phenotypes, our lab recently created a Myt1l heterozygous mutant mouse inspired by a clinically relevant mutation. This model recapitulates several of the physical and neurologic abnormalities seen in humans with MYT1L syndrome, such as weight gain, microcephaly, and behavioral disruptions. The majority of patients with this syndrome are young, and little is known about the impact of age on health and mortality in these patients. Using a Myt1l mutant …

Enhancing Progestin Therapy With A Glucagon-Like Peptide 1 Agonist For The Conservative Management Of Endometrial Cancer, Andrea R Hagemann, Ian S Hagemann, David G Mutch, Eric J Devor, Paige K Malmrose, Yuping Zhang, Abigail M Morrison, Kristina W Thiel, Kimberly K Leslie

2020-Current year OA Pubs

OBJECTIVE: Obesity is a major risk factor for endometrial cancer. In addition to hormone therapy with progestins, glucagon like peptide-1 receptor (GLP-1R) agonists such as semaglutide may be helpful to achieve weight loss during conservative treatment of endometrial hyperplasia or cancer.

METHODS: We theorized that the combination of semaglutide and the progestin levonorgestrel would be useful as a novel treatment or prevention regimen and tested this hypothesis using endometrial cancer cell lines and patient-derived organoids (PDOs).

RESULTS: Hec50, KLE, and Ishikawa endometrial cancer cells express GLP-1R, as determined by both qPCR and Western blotting, and GLP-1R agonist treatment induces GLP-1R …

Swog S1815: A Phase Iii Randomized Trial Of Gemcitabine, Cisplatin, And Nab-Paclitaxel Versus Gemcitabine And Cisplatin In Newly Diagnosed, Advanced Biliary Tract Cancers, Rachna T Shroff, Benjamin Tan, Et Al.

2020-Current year OA Pubs

PURPOSE: SWOG S1815 was a randomized, open label phase III trial, evaluating gemcitabine, nab-paclitaxel, and cisplatin (GAP) versus gemcitabine and cisplatin (GC) in patients with newly diagnosed advanced biliary tract cancers (BTCs).

METHODS: Patients with newly diagnosed locally advanced unresectable or metastatic BTC, including intrahepatic cholangiocarcinoma (ICC) and extrahepatic cholangiocarcinoma (ECC) and gallbladder carcinoma (GBC), were randomly assigned 2:1 to either GAP (gemcitabine 800 mg/m

RESULTS: Among 452 randomly assigned participants, 441 were eligible and analyzable, 67% with ICC, 16% with GBC, and 17% with ECC. There was no significant difference in overall survival (OS) between GAP versus GC. Median …

Systematic Evaluation Of Regression Models For The Prediction Of Influenza Cases, Mukul Kandwal

Theses

This study systematically evaluates machine learning models to forecast influenza outbreaks, aiming to enhance public health preparedness through accurate predictions. Laboratory-confirmed influenza case data from the New York State Department of Health (2009–2023) were used to train and test five regression models—XGBoost, Neural Network (MLP regressor), K-Nearest Neighbors (KNN), Random Forest, and Support Vector Regression (SVR)—with preprocessing techniques including differencing and phasing. A leave-one-season-out cross-validation framework and Symmetric Mean Absolute Percentage Error (SMAPE) were employed to rigorously assess performance. Key findings reveal that the Neural Network (MLP regressor) outperformed other models, achieving the lowest SMAPE score (23.7), underscoring the critical …