Digital Commons Network^™

Unh Gallery Of Art And Ogunquit Museum Of American Art Present “Networks Of Modernism: 1898- 1968”, Rebecca Colby

Digital Edition

No abstract provided.

Book Review Of Relinquished: The Politics Of Adoption And The Privilege Of American Motherhood By Gretchen Sisson. New York: St. Martin’S Press. 2024., Emily Stier Adler, Michele Hoffnung

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

State Of Utah, Plaintiff/ Appellee V. Celestine Anastacia Torstenson, Defendant/ Appellant : Reply Brief, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

appeal from the Second Judicial District Court, Weber County, Honorable Judge Bean, District Court No. 221902529

William M. Hains, Derek Brown, Counsel for Appellee

Freyja Johnson, Hannah Leavitt-Howell, Anna Grigsby, Counsel for Appellant

Ucf Libraries Promotion Criteria, Jason D. Phillips

Library Faculty

At UCF, library faculty are promoted on the basis of their professional effectiveness and their demonstrated record of achievement. As noted above, performance of Professional Responsibilities is the most important factor in promotion, as this accounts for the majority of a librarian’s annual responsibilities. Achievements in Research/Scholarship/Creative Works and Service are also required, with standards delineated later in the document.

Documents From The February 12, 2025 Meeting Of The Associated Students Of The University Of Montana (Asum)., Associated Students Of The University Of Montana

Senate Meeting Agendas and Minutes, 2007-Present

Minutes and agenda from the February 12, 2025 Meeting of the Associated Students of the University of Montana (ASUM).

The Texas County Appraisal System, Chad J. Pomeroy

St. Mary's Law Journal

No abstract provided.

The Mir-290 And Mir-302 Clusters Are Essential For Reprogramming Of Fibroblasts To Induced Pluripotent Stem Cells, Robert L Judson-Torres, Robert Blelloch

Faculty, Staff and Students Publications

The miR-290 and miR-302 clusters of microRNAs are highly expressed in naïve and primed pluripotent stem cells, respectively. Ectopic expression of the embryonic stem cell (ESC)-specific cell cycle regulating family of microRNAs arising from these two clusters dramatically enhances the reprogramming of both mouse and human somatic cells to induced pluripotency. Here, we used genetic knockouts to dissect the requirement for the miR-290 and miR-302 clusters during the reprogramming of mouse fibroblasts into induced pluripotent stem cells (iPSCs) with retrovirally introduced Oct4, Sox2, and Klf4. Knockout of either cluster alone did not negatively impact the efficiency of reprogramming. Resulting cells …

Increasing The Physician Workforce In Rural Hospitals, Tagny Isabel Diaz Solis

Walden Dissertations and Doctoral Studies

Rural hospitals experience challenges in supplying the physician workforce, leading to poor organizational and population health outcomes. The purpose of this integrative review was to determine factors that affect physician recruitment and retention in rural hospitals and provide strategies for administrators to support sufficient physician staffing. The review question was used to identify effective strategies to improve physician recruitment and retention in rural hospitals. An integrative review was completed using empirical and nonempirical research published between 2019 and 2024. The results of the literature demonstrated components affecting physician motivation and job satisfaction. Five main themes surfaced: (a) professional education, (b) …

Employee Turnover Intention In Automotive Manufacturing: An Examination Of Job Satisfaction Components For Leaders, James Edward Carlin Vi

Walden Dissertations and Doctoral Studies

Hiring managers in the automotive manufacturing industry have consistently faced high turnover rates compared to other sectors, prompting efforts to understand the factors influencing employees' intention to leave. Recognizing the impact of turnover on profitability and knowledge retention, these managers require deeper insights into the underlying relationships to develop effective mitigation strategies. Grounded in Herzberg’s motivation-hygiene theory, the purpose of this quantitative correlational study was to examine the relationship between interpersonal relationships, recognition, and turnover intention. The participants consisted of 155 first-line supervisors within the automotive industry in the Midwest United States who responded to the Minnesota Satisfaction Questionnaire Recognition …

Leaders’ Experience Of Spiritual Leadership Concerning Followership In Brazilian Organizations, Livia Mandelli

Walden Dissertations and Doctoral Studies

Spiritual leadership has been the focus of scholars since 2003. Researchers have demonstrated the relevance of spiritual leadership as a new leadership model. Researchers have yet been able to understand the practice of spiritual leadership in Latin America. The purpose of this phenomenological qualitative study was to describe the leaders’ lived experiences concerning followership, taking into consideration the meanings they ascribe to the relationship with their followers and the description of the subjective lived experiences of adopting spiritual leadership practice. The nexus between leaders’ lived experiences and their meaning regarding followership was given special consideration. This was a qualitative research …

Designing Patient-Centered Interventions For Emergency Care: Participatory Design Study, Jiaqi Li, Zhan Zhang, Hardeep Singh, Kalyan Pasupathy, Prashant Mahajan, Sun Young Park

Faculty, Staff and Students Publications

Background: Emergency departments (EDs) are high-pressure environments where clinicians diagnose patients under significant constraints, including limited medical histories, severe time pressures, and frequent interruptions. Current ED care practices often inadequately support meaningful patient participation. Most interventions prioritize clinical workflow and health care provider communication, inadvertently overlooking patients' needs. Additionally, patient-facing technologies in EDs are typically developed without meaningful patient input, leading to solutions that may not effectively address patients' specific challenges. To enhance both patient-centered care practices and the diagnosis process in EDs, patient involvement in technology design is essential to ensure their needs during emergency care are understood and …

In Vivo Expansion Of Gene-Targeted Hepatocytes Through Transient Inhibition Of An Essential Gene, Mingming Cao, Ayrea Hurley, Lavanya Saxena, Marcel A Chuecos, Christopher J Walkey, Alexandria M Doerfler, Mia N Furgurson, M Cecilia Ljungberg, Kalyani R Patel, Sarah Hyde, Tyler Chickering, Stephanie Lefebvre, Kelly Wassarman, Patrick Miller, June Qin, Mark K Schlegel, Ivan Zlatev, Jun Han, Christine Beeton, Rich Gang Li, Jong Kim, James F Martin, Karl-Dimiter Bissig, Vasant Jadhav, Gang Bao, William R Lagor

Faculty, Staff and Students Publications

Homology directed repair (HDR)-based genome editing is an approach that could permanently correct a broad range of genetic diseases. However, its utility is limited by inefficient and imprecise DNA repair mechanisms in terminally differentiated tissues. Here, we tested “Repair Drive”, a platform technology for selectively expanding HDR-corrected hepatocytes in adult mice in vivo. Repair Drive involves transient conditioning of the liver by knocking down an essential gene – fumarylacetoacetate hydrolase (Fah), and delivery of an untargetable version of the essential gene in cis with a therapeutic transgene. We show that Repair Drive increased the percentage of correctly …

Evaluation Of Platelet Rich Fibrin With Biodentine In Direct Pulp Therapy Of Permanent Teeth - An In-Vivo Study, Rhea M, Shruthi Nagaraja

Annual Research Symposium

No abstract provided.

Evidence Of Poor Oral Health For Individuals With Cardiovascular Disease, Maya Dagher, Ryan Moffat

Annual Research Symposium

No abstract provided.

Spartan Daily, February 12, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 164, Issue 9

Symphonic Winds: February 12, 2025, Dr. F. Mack Wood, Christopher Bulding

School of Music Programs

Center for the Performing Arts

February 12, 2025

Wednesday Evening

8:00 p.m.

Effect On Cardiovascular Outcome Of Sodium-Glucose Co-Transporter-2 (Sglt2) Inhibitors Among Cancer Patients Treated With Anthracycline: A Systematic Review And Meta-Analysis, Chalothorn Wannaphut, Phuuwadith Wattanachayakul, Sakditad Saowapa, Ben Ponvilawan, Manasawee Tanariyakul, Jakrin Kewcharoen, Pitchaporn Yingchoncharoen, Thanathip Suenghataiphorn, Noppawit Aiumtrakul, Jared Acoba

Department of Medicine Faculty Papers

Background/objectives: Sodium-glucose-co-transporter-2 (SGLT2) inhibitors have shown benefit in reducing cardiovascular disease outcomes in diabetes patients. Anthracycline therapy is associated with a risk of cardiomyopathy. However, the impact of SGLT2 inhibitors in the prevention of cardiomyopathy and heart failure in cancer patients undergoing anthracycline treatment remains unclear. Thus, we conducted a systematic review and meta-analysis to explore the effect of the prevention of cardiovascular outcomes in patients with cancer and diabetes who had received anthracycline therapy.

Methods: We systematically reviewed Medline and EMBASE databases from inception to January 2024 for studies focusing on cancer patients with a history of anthracycline therapy. …

Executive Watch: Introduction, Timothy Zick

Popular Media

First installment in a regular feature on the Trump administration and the First Amendment.

Artsksu Presents: The Music Of Stacy Garrop

Bailey School of Music Concert Programs

ArtsKSU Presents: The Music of Stacy Garrop

Mapping The Numbers Of Dementia In Brazil: A Delphi Consensus Study, Márlon Juliano Romero Aliberti, Claudia Kimie Suemoto, Jerson Laks, Paulo Caramelli, Sonia Maria Dozzi Brucki, Nicolas Farina, Daniel Apolinario, Einstein Francisco Camargos, Eleonora D'Orsi, Gilberto Sousa Alves, Karolina Gouveia César-Freitas, Luís Fernando Rangel, Márcia Lorena Fagundes Chaves, Marcos Antonio Lopes, Marcus Vinicius Della Coletta, Matheus Ghossain Barbosa, Norberto Anizio Ferreira Frota, Ricardo Nitrini, Cleusa Pinheiro Ferri

Peninsula Medical School

OBJECTIVES: As the global dementia crisis intensifies, especially in low-and middle-income countries (LMICs), there is a pressing need for comprehensive prevalence data across diverse regions, including Brazil, where studies have been predominantly limited to affluent urban centers. This study aimed to conduct an expert consensus to determine the prevalence of all-cause dementia in Brazil, considering various age groups, sexes, and geographical areas.

METHODS: A Delphi consensus process with clinical and academic experts from across Brazil was conducted to provide dementia prevalence estimates in people aged ≥ 60 years living throughout Brazil for 2019. Each round consisted of answering structured questionnaires …

Handshake Antimicrobial Stewardship For Adult Surgical Patients, Abby Kosharek, Elizabeth Neuner, Emily Welch, Spenser January, Alice Bewley, Kevin Hsueh, Sena Sayood

2020-Current year OA Pubs

OBJECTIVE: Evaluate the effects of handshake stewardship on adult general surgical units.

DESIGN: Retrospective quasi-experimental pre- and post-intervention study.

SETTING: A total of 1,278 bed academic medical center with a level 1 trauma center in St. Louis, Missouri.

PATIENTS: Adults admitted to general surgery units.

INTERVENTION: Once weekly handshake antimicrobial stewardship rounds were initiated in January 2022 on adult general surgery units. The handshake stewardship team consisted of an infectious diseases (ID) physician and pharmacist who reviewed charts of patients receiving systemic antimicrobials without a formal ID consult. Antimicrobial recommendations were delivered in person to general surgery teams including trauma, …

Exploring Research Culture In Care Homes To Identify The Barriers And Facilitators To Research: A Rapid Review, Gary Hodge, Lisa Burrows, Georgia Page, Susie Pearce

School of Nursing and Midwifery

AbstractContext: There are more than 400,000 people living in just over 17,000 care homes in the UK. Nevertheless, the quantity of care home research taking place in these settings is limited. This has led to a knowledge gap that impacts on care home practices, resident health outcomes, and the development of policy.Objectives: The objective of this rapid review is to explore what is known about the research culture within care homes, identify any barriers and facilitators to research, and provide evidence to inform future care home research practices.Methods: This rapid review was performed in accordance with the Cochrane Rapid Review …

Dna Immunotherapy For Recurrent Respiratory Papillomatosis (Rrp): Phase 1/2 Study Assessing Efficacy, Safety, And Immunogenicity Of Ino-3107, Matthew P Morrow, Randal C Paniello, Et Al.

2020-Current year OA Pubs

Recurrent respiratory papillomatosis (RRP) is a chronic airway disease caused by Human Papillomavirus (HPV). INO-3107, DNA immunotherapy designed to elicit T-cells against HPV-6 and HPV-11, was evaluated in a 52-week Phase 1/2 study for efficacy, safety, and immunogenicity (NCT04398433). Thirty-two eligible adults with HPV-6 and/or HPV-11 RRP, requiring ≥2 surgical interventions in the year preceding dosing were enrolled between October 2020 and November 2021 and administered 4 INO-3107 doses by intramuscular injection followed by electroporation. The primary endpoint was safety and tolerability, as assessed by treatment-emergent adverse events (TEAEs). Secondary endpoints included surgical intervention frequency and change in RRP Severity …

Phgdh Inhibition And Foxo3 Modulation Drives Puma-Dependent Apoptosis In Osteosarcoma, Toshinao Oyama, Caitlyn B Brashears, Richa Rathore, Heather Benect-Hamilton, Katharine E Caldwell, Naomi Dirckx, William G Hawkins, Brian A Van Tine

2020-Current year OA Pubs

Osteosarcoma is a bone cancer that has been found to be metabolically dependent on the conversion of glucose to serine through the rate-limiting enzyme 3-phosphoglycerate dehydrogenase (PHGDH). The upregulation of PHGDH has been correlated with poor patient survival, and the inhibition of the serine synthesis pathway using targeted small-molecule inhibition of PHGDH induces a rapid metabolic adaptation that prevents cell death due to pro-survival signaling through the mammalian target of rapamycin complex 1 (mTORC1) pathway. Here, PHGDH inhibition in combination with mTORC1 signaling modulation for the treatment of osteosarcoma was evaluated. When combined with PHGDH inhibition, several non-rapalog inhibitors of …

Fiber- And Acetate-Mediated Modulation Of Mhc-Ii Expression On Intestinal Epithelium Protects From Clostridioides Difficile Infection, José L Fachi, Tihana Trsan, Silvia Penati, Susan Gilfillan, Siyan Cao, Krzysztof L Hyrc, Xiuli Liu, Patrick Fernandes Rodrigues, Bishan Bhattarai, Marco Colonna, Et Al.

2020-Current year OA Pubs

Here, we explore the relationship between dietary fibers, colonic epithelium major histocompatibility complex class II (MHC-II) expression, and immune cell interactions in regulating susceptibility to Clostridioides difficile infection (CDI). We find that a low-fiber diet increases MHC-II expression in the colonic epithelium, which, in turn, worsens CDI by promoting the development of pathogenic CD4

2025-02-12 Seattle U Committee Fights Against Banned Books, Hadia Noor Ahmed, Naja Johnson

The Spectator Online

No abstract provided.

2025-02-12 Super Bowl Lix: Eagles Fly, Mahomes Lays Egg, Daniel Truog

The Spectator Online

No abstract provided.

Exploring The Validity Of Adolescent Responses To A Measure Of Psychological Flexibility And Inflexibility, Caleb D. Farley, Tyler L. Renshaw

Psychology Student Research

Validating measures of psychological flexibility (PF) and psychological inflexibility (PI) has occurred in multiple adult samples, but little research has validated PF and PI measures with adolescents. This manuscript describes two studies exploring the validity of responses to the Multidimensional Psychological Flexibility Inventory (MPFI) with two samples of adolescents. The first study used exploratory factor analyses on responses to the MPFI with a sample of 16–17-year-olds (N = 249). The results yielded a reduced and simplified measurement model that consisted of two general factors: one for PF and the other for PI. These exploratory findings were further investigated with …

An Analytical Prior Selection Procedure For Empirical Bayesian Analysis Using Resampling Techniques: A Simulation-Based Approach Using The Pancreatic Adenocarcinoma Data From The Seer Database, Aditya Chakraborty, Mohan D. Pant

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Introduction: In the field of medical research, empirical Bayesian analysis has emerged as an increasingly applicable approach. This statistical framework offers greater flexibility, enabling researchers to incorporate prior information and rigorously estimate parameters of interest. However, the selection of suitable prior distributions can be a challenging endeavor, with profound implications for the resulting inferences. To address this challenge, this study proposes a new analytical procedure that leverages resampling techniques to guide the choice of priors in Bayesian analysis. Subject and Methods: The study group consisted of patients who had been diagnosed and had died of pancreatic adenocarcinoma (cause-specific death) who …

Midweek Memo, Georgia Southern University

Midweek Memo

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