Digital Commons Network^™

Incorporation Of Xai And Deep Learning In Biomedical Imaging: A Review, Sushil K. Singh, Bal Virdee, Saurabh Aggarwal, Abhilash Maroju

Polytechnic Journal

Artificial Intelligence (AI) and Deep Learning (DL) technologies have revolutionized disease detection, particularly in Medical Imaging (MI). While these technologies demonstrate outstanding performance in image classification, their integration into clinical practice remains gradual. A significant challenge lies in the opacity of Deep Neural Network (DNN) models, which provide predictions without explaining their structure. This lack of transparency poses severe issues in the healthcare industry, as trust in automated technologies is critical for doctors, patients, and other stakeholders. Concerns about liability in autonomous car accidents are comparable to those associated with deep learning applications in medical imaging. Errors such as false …

An Attention-Based Model For Recognition Of Facial Expressions Using Cnn-Bilstm, Sushil Kumar Singh, Manish Kumar, Ikram Majeed Khan, A. Jayanthiladevi, Chirag Agarwal

Polytechnic Journal

In recent studies, computer vision and human-computer interaction have focused heavily on facial expression recognition (FER). Traditional deep learning algorithms have faced significant challenges when processing images with occlusion, uneven lighting, and positional inconsistencies and addressing dataset imbalances. These issues often result in low accuracy, unreliable recognition rates, and slow convergence. To address the challenges posed by non-frontal visual features, this study proposes a hybrid model that fusion of Convolutional Neural Networks (CNN) and Bidirectional Long Short-Term Memory (BiLSTM), augmented with a point-multiplication attention model and Linear Discriminant Analysis (LDA). Data preparation incorporates median filtering and global contrast normalization to …

Cumberland Pharmacy Faculty Research Award, University Of Mississippi. School Of Pharmacy

Pharmacy Awards

No abstract provided.

Black Women Healing From Gender-Based Violence: Christ-Centered Approaches For Transformative Holistic Wellbeing, Tanya Jahwar

Doctor of Ministry

The Women’s Leadership and Resource Center states, “Gender-based violence against Black women has always existed in the US. From historical accounts of chattel slavery to analyses of present-day society, Black women have endured multiple forms of violence including labor …, sexual …, medical … and … exploitation.”³² This dissertation will provide important research about gender-based violence against Black women and girls and will conclude with Christ-centered approaches for transformative holistic wellbeing. Do laws that prevent violence enable more violence? In the fact sheet published by the National Black Women’s Justice Institute, it is noted that, “Experiences of abuse do …

Access To Arynes From Arenes Via Net Dehydrogenation: Scope, Synthetic Applications And Mechanistic Analysis, Riley A. Roberts, Bryan E. Metze, Nicole Javaly, Theresa M. Mccormick, David R. Stuart

Chemistry Faculty Publications and Presentations

Arynes undergo a wide range of chemical transformations making them versatile reactive intermediates for organic synthesis. Access to arynes has long been dominated by pre-functionalised reagents, e.g., the venerable o-trimethylsilylaryl triflates. However, a move toward developing methods to access arynes that are both mild and efficient has prompted research into aryl “onium” aryne precursors. Here, we leverage aryl “onium” species as in situ or isolated intermediates in a net dehydrogenation of simple arenes as a novel and efficient way to access arynes. We describe a unified strategy in which two different tactics are employed to access diversely substituted …

Automated Detection Of Reduced Ejection Fraction Using An Ecg-Enabled Digital Stethoscope: A Large Cohort Validation, Ling Guo, Gregg S. Pressman, Spencer N. Kieu, Scott B. Marrus, George Mathew, John Prince, Emileigh Lastowski, Rosalie V. Mcdonough, Caroline Currie, John N. Maidens, Hussein Al-Sudani, Evan Friend, Deepak Padmanabhan, Preetham Kumar, Edward Kersh, Subramaniam Venkatraman, Salima Qamruddin

Einstein Health Papers

BACKGROUND: Asymptomatic left ventricular systolic dysfunction (ALVSD) affects 7 million globally, leading to delayed diagnosis and treatment, high mortality, and substantial downstream health care costs. Current detection methods for ALVSD are inadequate, necessitating the development of improved diagnostic tools. Recently, electrocardiogram-based algorithms have shown promise in detecting ALVSD.

OBJECTIVES: The authors developed and validated a convolutional neural network (CNN) model using single-lead electrocardiogram and phonocardiogram inputs captured by a digital stethoscope to assess its utility in detecting individuals with actionably low ejection fractions (EF) in a large cohort of patients.

METHODS: 2,960 adults undergoing echocardiography from 4 U.S. health care …

2025 February 20 - From My Notepads Newsletter, Office Of The President, East Tennessee State University, Brian Noland

From My Notepads: A Newsletter from President Brian Noland

No abstract provided.

Honors Faculty Research Talks Crystal Jiang, Ph.D, Crystal Jiang

Honors Programs

No abstract provided.

Lowell Hardin: Mentor Extraordinaire, Larry L. Murdock, Thomas W. Hertel, Gebisa Ejeta

Purdue University Press Books

Lowell Stewart Hardin (1917–2015), an Indiana farm boy who became an enormously influential international agriculturalist, made the world a better place for the poor and the hungry on this earth. For seventeen years he led the Ford Foundation’s agricultural development efforts, contributing to the Green Revolution. He helped to found and guide international agriculture research centers in Africa, Asia, and Latin America. He inspired others to get involved and opened doors for them. He taught by example, gave others credit, and always stepped back, avoiding the limelight himself. In this volume, twenty-two people who knew him well share stories of …

Glenn Howard Griffin, Petitioner/ Appellant V. State Of Utah, Respondent/ Appellee : Reply Brief, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

Several of the State’s arguments misconstrue Glenn’s arguments. Other positions fail to address arguments that Glenn has made. This reply memorandum highlights the various deficiencies in the State’s arguments

Re: Comment Letter For Draft Blacktail Creek Groundwater Hydraulic Control System Preliminary 30% Remedial Design Report (Dated October 28, 2024), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Бадхызские Архивы. Том 2, Р. И. Горелова, В. Я. Фет

Open Access Books

Gorelova, RI, Fet V, editors. The Badkhyz Archives, Vol. 2. Huntington, WV: Marshall University Libraries; 2025. 387 p.

This book represents the second volume of the series started in 2021. It compiles memoirs and research information about the unique Badkhyz Natural Reserve, now in Turkmenistan, formerly at the southernmost point of the USSR. Established in 1941, the Reserve—nicknamed a Serengeti of Central Asia— housed many unique and endangered species, with an iconic wild ass, or kulan, preserved only there. The second volume includes unique and otherwise unavailable information about the workers of the Reserve in 1940s-1980s. We continuento publish …

Efficacy And Safety Of Different Atropine Regimens For The Treatment Of Myopia In Children Three-Year Results Of The Mosaic Randomized Clinical Trial, James Loughman, Gareth Lingham, Ernest Kyei Nkansah, Emmanuel Kobia-Acquah, Daniel Ian Flitcroft

Research Outputs: 2025-Present

IMPORTANCE Additional data are required regarding atropine treatment regimens for control of myopia progression. OBJECTIVE To investigate the efficacy and safety of different atropine regimens for myopia in children. DESIGN, SETTING, AND PARTICIPANTS This was a secondary analysis of the 3-year results of the 24-Month Myopia Outcome Study of Atropine in Children (MOSAIC) trial, called the MOSAIC2 trial. The MOSAIC trial was an investigator-led, double-masked, randomized clinical trial of different atropine concentrations and regimens. The MOSAIC2 study took place at the Centre for Eye Research Ireland, in Dublin, Ireland, and included children and adolescents with myopia from the MOSAIC trial. …

Effects Of Acute Pro-Inflammatory Stimulation And 25-Hydroxycholesterol On Hippocampal Plasticity And Learning Involve Nlrp3 Inflammasome And Cellular Stress Responses, Yukitoshi Izumi, Kazuko A O'Dell, Steven Mennerick, Charles F Zorumski

2020-Current year OA Pubs

Neuroinflammation is an increasingly important target for therapeutics in neuropsychiatry and contributes to cognitive dysfunction, disability and death across a range of illnesses. We previously found that acute effects of pro-inflammatory stimulation with lipopolysaccharide (LPS) on hippocampal long-term potentiation (LTP), a form of synaptic plasticity involved in learning and memory, requires synthesis of the oxysterol, 25-hydroxycholesterol (25HC) and exogenous 25HC mimics effects of LPS. However, downstream mechanisms engaged by LPS and 25HC remain uncertain. Here we use rat hippocampal slices and in vivo behavioral studies to provide evidence that acute modulation of synaptic plasticity by both LPS and 25HC requires …

Generative Adversarial Network For Image Reconstruction From Human Brain Activity., Tim Tanner, Vassilis Cutsuridis

School of Engineering, Computing and Mathematics

Decoding of brain activity with machine learning has enabled the reconstruction of thoughts, memories and dreams. In this study, we designed a methodology for reconstructing visual stimuli (digits) from human brain activity recorded during passive visual viewing. Using the MindBigData EEG dataset, we preprocessed the signals and cleaned them from noise, muscular artifacts and eye blinks. Using the Common Average Reference (CAR) method and past studies’ results we reduced the available electrodes from 14 to 4 keeping only those containing discriminative features associated with the visual stimulus. A convolutional neural network (CNN) was then trained to encode the signals and …

Reneu: A Pivotal, Phase Iib Trial Of Mirdametinib In Adults And Children With Symptomatic Neurofibromatosis Type 1-Associated Plexiform Neurofibroma, Christopher L Moertel, Angela C Hirbe, Et Al.

2020-Current year OA Pubs

PURPOSE: Pharmacologic therapies for neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PNs) are limited; currently, none are US Food and Drug Administration-approved for adults.

METHODS: ReNeu is an open-label, multicenter, pivotal, phase IIb trial of mirdametinib in 58 adults (≥18 years of age) and 56 children (2 to 17 years of age) with NF1-PN causing significant morbidities. Patients received mirdametinib capsules or tablets for oral suspension (2 mg/m

RESULTS: Twenty-four of 58 adults (41%) and 29 of 56 children (52%) had a BICR-confirmed objective response during the 24-cycle treatment phase; in addition, two adults and one child had confirmed responses during long-term …

Integrating Quantum Computing In High-Frequency Trading: A Project Management Approach, Dhwani Patel, Dhwani Patel

Harrisburg University Dissertations and Theses

This thesis explores the integration of quantum computing in high-frequency trading (HFT) from a project management perspective. As quantum computing emerges as a transformative technology, its potential to revolutionize financial markets, particularly HFT, necessitates structured approaches to manage the associated complexities and risks. Agile methodologies are examined as a solution to bridge the gap between the rapid development cycles of quantum software and the high-speed requirements of trading algorithms. The study employs a qualitative research approach, incorporating expert interviews and literature analysis to identify the challenges and opportunities of implementing quantum computing in HFT. The research reveals that while quantum …

Agile Project Management And The Future Of R&D, Aditi Vinayak Nalavade

Harrisburg University Dissertations and Theses

The use of Agile methodologies in research and development (R&D) sectors is changing the project management landscape by profoundly altering approaches to innovation and execution. This research will delve into the benefits and challenges of implementing Agile in an R&D setting, with a particular focus on the increasing significance of AI. The research's central theme offers a comprehensive analysis of how Agile approaches are shaping the future of R&D. Agile's iterative process, with its high degree of adaptability, flexibility, and iterative methods, is particularly beneficial in R&D, where reshaping research teams' approaches to creativity and problem-solving even in the most …

Synergistic Effects Of Bacillus Coagulans And Β-Glucans: Potential Benefits Of Probiotic And Prebiotic Use On The Gastrointestinal Tract And Microbiome In Humans, Jennifer Bermudez

Annual Research Symposium

No abstract provided.

Spartan Daily, February 20, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 164, Issue 13

The Grizzly, February 20, 2025, Kate Horan, Sidney Belleroche, Renee Washart, Claudia Tracy, Adam Denn, Ashley Adam

Ursinus College Grizzly Newspaper, 1978 to Present

Sigma Gamma Rho: Semester of Service • The UC Tonight Modern Band • BearShare Now Open! • After the Career Fair: Checklist • Bird is the Word! • El Gordo Bros: Adding Flavor to Collegeville • Opinions: Bear-Bones • Ursinus Swimming Set for Championships! • A Wonderful Weekend of Sports: February 15-16th

Coastal And Rural Digital Exclusion - The Case For Voice Ai, Rory Baxter, Oksana Hagen, Amir Aly, Ray Jones, Katharine Willis

School of Nursing and Midwifery

The adoption of digital platforms for health and social resources disadvantages vulnerable populations, including older adults and those living in remote or deprived areas. This could be remediated using voice-based conversational AI (Voice AI) systems delivered via landline phone, bypassing the requirement for digital device access or digital skills. British rural and coastal regions often have poorer digital infrastructure and pockets of deprivation, and consequently higher levels of digital exclusion. This study explores digital exclusion in Southwest England and the suitability of Voice AI systems for supporting digital inclusion. Seventeen participants aged 50 years or over were interviewed by telephone …

聖霊と共に学ぶ２, Yoshihiko Ariizumi

Spiritual Proficiency

わたしたちは聖霊ともっと親しく触れながら学ぶことに、学び方を飛躍させることができ、さまざまな難しい状況でも平安を保つことができます。頭でわかってもなかなか実行できないこともあると思いますが、この資料で、成功するためのたくさんのヒントが見つかり、勇気をもらえると思います。

Seeing The Unseen: Procedural Solutions In Plain Sight, Melissa Mortazavi

Other Faculty Publications

No abstract provided.

Illinois State University Founding Celebration Program, February 20, 2025, Illinois State University

Founding Celebration Programs

Program for annual event celebrating the founding of Illinois State Normal University on February 18, 1857.

A Comprehensive Survey Of Data-Driven Solutions For Lorawan: Challenges And Future Directions, Poonam Maurya, Abhishek Hazra, Preti Kumari, Troels Bundgaard Sørensen, Sajal K. Das

Computer Science Faculty Research & Creative Works

Long-range Wide-area Network (LoRaWAN) is an innovative and prominent communication protocol in the domain of Low-power Wide-area Networks (LPWAN), known for its ability to provide long-range communication with low energy consumption. However, the practical implementation of the LoRaWAN protocol, operating at the Medium Access Control layer and specially built to work upon the LoRa physical layer, presents numerous research challenges, including network congestion, interference, optimal resource allocation, collisions, scalability, and security. To mitigate these challenges effectively, the adoption of cutting-edge data-driven technologies such as Deep Learning (DL) and Machine Learning (ML) emerges as a promising approach. Interestingly, very few existing …

Montana Kaimin, February 20, 2025, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Semaglutide And Nonarteritic Anterior Ischemic Optic Neuropathy, Swarup S Swaminathan, Brian Toy, Benjamin Xu, John Chen, Aiyin Chen, Sophia Wang, Cecilia Lee, Theodore Leng, Joshua R Ehrlich, Andrew Barkmeier, Karen R Armbrust, Michael V Boland, David Dorr, Danielle Boyce, Thamir Alshammari, Joel Swerdel, Marc A Suchard, Martijn Schuemie, Anthony G Sena, George Hripcsak, Akihiko Nishimura, Paul Nagy, Thomas Falconer, Scott L Duvall, Michael Matheny, Benjamin Viernes, William O'Brien, Linying Zhang, Benjamin Martin, Erik Westlund, Nestoras Mathioudakis, Ruochong Fan, Adam Wilcox, Albert Lai, Jacqueline C Stocking, Sahar Takkouche, Lok Hin Lee, Yangyiran Xie, Izabelle Humes, David B Mccoy, Mohammad Adibuzzaman, Raymond G Areaux, William Rojas-Carabali, James Brash, David A Lee, Nicole G Weiskopf, Louise Mawn, Rupesh Agrawal, Hannah Morgan-Cooper, Priya Desai, Patrick B Ryan

Faculty, Staff and Student Publications

Importance

Semaglutide, a glucagonlike peptide-1 receptor agonist (GLP-1RA), has recently been implicated in cases of nonarteritic anterior ischemic optic neuropathy (NAION), raising safety concerns in the treatment of type 2 diabetes (T2D).

Objective

To investigate the potential association between semaglutide and NAION in the Observational Health Data Sciences and Informatics (OHDSI) network.

Design, Setting, and Participants

This was a retrospective study across 14 databases (6 administrative claims and 8 electronic health records). Included were adults with T2D taking semaglutide, other GLP-1RA (dulaglutide, exenatide), or non–GLP-1RA medications (empagliflozin, sitagliptin, glipizide) from December 1, 2017, to December 31, 2023. The incidence proportion …

Erythritol, Erythronate, And Cardiovascular Outcomes In Older Adults In The Aric Study, Chao Cheng, Ashok Balasubramanyam, Jane Eb Reusch, Elizabeth Selvin, Chiadi E Ndumele, Vijay Nambi, Christie M Ballantyne

Faculty, Staff and Student Publications

BACKGROUND: Circulating erythritol, an endogenously produced metabolite and an artificial sweetener, is associated with cardiovascular outcomes.

OBJECTIVES: The authors assessed associations of erythritol and its downstream metabolite, erythronate, with cardiovascular risk factors and events in older adults in the ARIC (Atherosclerosis Risk In Communities) study (visit 5, 2011-2013).

METHODS: We included 4,006 participants without prevalent cardiovascular disease and with metabolomic profiling. Erythritol and erythronate were measured by mass spectrometry. We analyzed associations of log-transformed erythritol and erythronate with cardiovascular risk factors and events using Cox proportional hazard models.

RESULTS: Participants in the highest tertiles of erythritol or erythronate were older, …

February 2025 Academic Affairs Minutes, University Of Nebraska At Kearney Academic Affairs Committee

Academic Affairs Committee Minutes

No abstract provided.