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Regulation Of Transcription And Chromatin Structure By Prb: Here, There And Everywhere, Srikanth Talluri, Frederick A. Dick Sep 2012

Regulation Of Transcription And Chromatin Structure By Prb: Here, There And Everywhere, Srikanth Talluri, Frederick A. Dick

Paediatrics Publications

Commitment to divide is one of the most crucial steps in the mammalian cell division cycle. It is critical for tissue and organismal homeostasis, and consequently is highly regulated. The vast majority of cancers evade proliferative control, further emphasizing the importance of the commitment step in cell cycle regulation. The Retinoblastoma (RB) tumor suppressor pathway regulates this decision-making step. Since being the subject of Knudson's 'two hit hypothesis', there has been considerable interest in understanding pRB's role in cancer. It is best known for repressing E2F dependent transcription of cell cycle genes. However, pRB's role in controlling chromatin structure is …


Cystatin C For The Assessment Of Gfr In Neonates With Congenital Renal Anomalies, Guido Filler, Joanne Grimmer, Shih Han Susan Huang, Erika Bariciak Sep 2012

Cystatin C For The Assessment Of Gfr In Neonates With Congenital Renal Anomalies, Guido Filler, Joanne Grimmer, Shih Han Susan Huang, Erika Bariciak

Paediatrics Publications

No abstract provided.


Cortical Circuitry Associated With Reflex Cardiovascular Control In Humans: Does The Cortical Autonomic Network "Speak" Or "Listen" During Cardiovascular Arousal, J. Kevin Shoemaker, Savio W. Wong, David F. Cechetto Sep 2012

Cortical Circuitry Associated With Reflex Cardiovascular Control In Humans: Does The Cortical Autonomic Network "Speak" Or "Listen" During Cardiovascular Arousal, J. Kevin Shoemaker, Savio W. Wong, David F. Cechetto

Paediatrics Publications

Beginning with clinical evidence of fatal cardiac arrhythmias in response to severe stress, in epileptic patients, and following stroke, the role of the cerebral cortex in autonomic control of the cardiovascular system has gained both academic and clinical interest. Studies in anesthetized rodents have exposed the role of several forebrain regions involved in cardiovascular control. The introduction of functional neuroimaging techniques has enabled investigations into the conscious human brain to illuminate the temporal and spatial activation patterns of cortical regions that are involved with cardiovascular control through the autonomic nervous system. This symposia report emphasizes the research performed by the …


Mechanisms In Decorin Regulation Of Vascular Endothelial Growth Factor-Induced Human Trophoblast Migration And Acquisition Of Endothelial Phenotype, Neena Lala, Gannareddy V. Girish, Alia Cloutier-Bosworth, Peeyush K. Lala Sep 2012

Mechanisms In Decorin Regulation Of Vascular Endothelial Growth Factor-Induced Human Trophoblast Migration And Acquisition Of Endothelial Phenotype, Neena Lala, Gannareddy V. Girish, Alia Cloutier-Bosworth, Peeyush K. Lala

Paediatrics Publications

Extravillous trophoblast (EVT) cells of the human placenta invade the uterine decidua and utero-placental arteries to establish an efficient exchange of key molecules between maternal and fetal blood. Trophoblast invasion is stringently regulated in situ both positively and negatively by a variety of factors at the fetal-maternal interface to maintain a healthy utero-placental homeostasis. One such factor, decorin, a transforming growth factor (TGF)-beta binding, leucine-rich proteoglycan produced by the decidua, negatively regulates EVT proliferation, migration, and invasiveness independent of TGFbeta.We reported that these decorin actions were mediated by its binding to multiple tyrosine kinase receptors, including vascular endothelial growth factor …


Ideas Matter: A Comparative Analysis Of Two Neighbourhood Regeneration Programs Associated With The Administrations Of Two Toronto Mayors Between 2005 And 2012, Kathy Wiele Sep 2012

Ideas Matter: A Comparative Analysis Of Two Neighbourhood Regeneration Programs Associated With The Administrations Of Two Toronto Mayors Between 2005 And 2012, Kathy Wiele

MPA Major Research Papers

This paper examines how the neighbourhood regeneration programs of David Miller and Rob Ford in Toronto compare based on the approaches to public administration taken by each mayor. It uses a comparative analysis of the two cases with a specific focus on Miller’s Priority Neighbourhoods (PNs) and Ford’s Neighbourhood Improvement Areas (NIAs). The findings reveal that the two programs are based on different approaches to public administration, with Miller emphasizing the community development approach and Ford favouring the economic model of public administration.


The Determinants Of Human Creativity/Ingenuity: A Case Study Of Teacher Candidates At Notodden, Ronald Hansen Sep 2012

The Determinants Of Human Creativity/Ingenuity: A Case Study Of Teacher Candidates At Notodden, Ronald Hansen

Publications

Every child is born with a natural curiosity and fertile imagination. This innate ability and disposition is seldom clearly defined or understood, however. The literature abounds with speculation about the nature of creativity in people. Reference is made to a potpourri of words that conjure up what a creative individual/child would do or how he/she might behave (the ability to solve problems, generate ideas, think laterally, play imaginatively, design, make things, act spontaneously, fantasize, laugh). The instinct to identify and solve problems and do it creatively is often identified as a fundamental trait of being human, yet its core determinants …


Poverty, Work And Social Networks: The Role Of Social Capital For Aboriginal People In Urban Australian Locales, Julie Lahn Sep 2012

Poverty, Work And Social Networks: The Role Of Social Capital For Aboriginal People In Urban Australian Locales, Julie Lahn

Aboriginal Policy Research Consortium International (APRCi)

In this article, I present the key findings from a project entitled “The Social Context of Indigenous Poverty”. The research involved a series of interviews with Aboriginal people in urban SE Australia on issues of poverty, social capital and social exclusion. In the article I draw together Aboriginal perspectives on the meaning of poverty to reflect on the relevance of social capital concepts for understanding Aboriginal economic disadvantage and hence, the merits of policy framed in these terms.


Women And Girls Fleeing Conflict: Gender And The Interpretation And Application Of The 1951 Refugee Convention, Valerie Oosterveld Sep 2012

Women And Girls Fleeing Conflict: Gender And The Interpretation And Application Of The 1951 Refugee Convention, Valerie Oosterveld

Law Publications

No abstract provided.


Deaf Apostolate Newsletter, Fall 2012 Sep 2012

Deaf Apostolate Newsletter, Fall 2012

Deaf Apostolate Newsletter

A newsletter published for Deaf Catholics in Boston, MA

Deaf Apostolate Newsletter Finding Aid


As I Recall…September 2012, Lee County Medical Society Sep 2012

As I Recall…September 2012, Lee County Medical Society

As I Recall Column

"As I Recall…" Column written by Dr. Roger D. Scott for the September 2012 Lee County Medical Society Bulletin newsletter. The entire Bulletin is included, but "As I Recall…" is on page 3.


Adobe Medicus 2012 5 September-October, Health Sciences Library And Informatics Center Sep 2012

Adobe Medicus 2012 5 September-October, Health Sciences Library And Informatics Center

adobe medicus

No abstract provided.


Ntid Focus Fall 2012, Ntid Marketing And Communications Sep 2012

Ntid Focus Fall 2012, Ntid Marketing And Communications

National Technical Institute for the Deaf Papers

No abstract provided.


Arabidopsis Scaffold Protein Rack1a Modulates Rare Sugar D-Allose Regulated Gibberellin Signaling, Hemayet Ullah Sep 2012

Arabidopsis Scaffold Protein Rack1a Modulates Rare Sugar D-Allose Regulated Gibberellin Signaling, Hemayet Ullah

Department of Biology Faculty Publications

As energy sources and structural components, sugars are the central regulators of plant growth and development. In addition to the abundant natural sugars in plants, more than 50 different kinds of rare sugars exist in nature, several of which show distinct roles in plant growth and development. Recently, one of the rare sugars, D-allose, an epimer of D-glucose at C3, is found to suppress plant hormone gibberellin (GA) signaling in rice. Scaffold protein RACK1A in the model plant Arabidopsis is implicated in the GA pathway as rack1a knockout mutants show insensitivity to GA in GA-induced seed germination. Using genetic knockout …


Njit Highlanders Men's Soccer 2012 Media Guide, New Jersey Institute Of Technology Athletic Department Sep 2012

Njit Highlanders Men's Soccer 2012 Media Guide, New Jersey Institute Of Technology Athletic Department

Soccer - Men's

No abstract provided.


Longitudinal Associations Between Executive Control And Developing Mathematical Competence In Preschool Boys And Girls, Caron A. C. Clark, Tiffany Sheffield, Sandra A. Wiebe, Kimberly A. Espy Sep 2012

Longitudinal Associations Between Executive Control And Developing Mathematical Competence In Preschool Boys And Girls, Caron A. C. Clark, Tiffany Sheffield, Sandra A. Wiebe, Kimberly A. Espy

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

Executive control (EC) is related to mathematics performance in middle childhood. However, little is known regarding how EC and informal numeracy differentially support mathematics skill acquisition in preschoolers. A sample of preschoolers (115 girls, 113 boys), stratified by social risk, completed an EC task battery at 3 years, informal numeracy assessments at 3.75 and 4.5 years, and a broad mathematics assessment during kindergarten. Strong associations were observed between latent EC at age 3 and mathematics achievement in kindergarten, which remained robust after accounting for earlier informal numeracy, socioeconomic status, language and processing speed. Relations between EC and mathematics achievement were …


Virtue Ethics, Care Ethics, And "The Good Life Of Teaching", Marissa Silverman Sep 2012

Virtue Ethics, Care Ethics, And "The Good Life Of Teaching", Marissa Silverman

John J. Cali School of Music Scholarship and Creative Works

In "The Good Life of Teaching: An Ethics of Professional Practice," Chris Higgins (2011) reminds people that "self-interest and altruism, personal freedom and social roles, and practical wisdom and personhood" have been ancient philosophical topics that remain vitally important in the practice of contemporary teaching and learning. One of the most fundamental questions Higgins raises is this: "How do we reconcile self-regard and concern for others?" Higgins echoes John Dewey's concern for "balancing the distinctive capacity of an individual with his social service." In other words, and educationally speaking: What does it mean to live "the good life" as an …


Macrophage Autophagy In Immunity To Cryptococcus Neoformans And Candida Albicans, Magdia De Jesus Sep 2012

Macrophage Autophagy In Immunity To Cryptococcus Neoformans And Candida Albicans, Magdia De Jesus

Biomedical Sciences Faculty Scholarship

Autophagy is used by eukaryotes in bulk cellular material recycling and in immunity to intracellular pathogens. We evaluated the role of macrophage autophagy in the response to Cryptococcus neoformans and Candida albicans, two important opportunistic fungal pathogens. The autophagosome marker LC3 (microtubule-associated protein 1 light chain 3 alpha) was present in most macrophage vacuoles containing C. albicans. In contrast, LC3 was found in only a few vacuoles containing C. neoformans previously opsonized with antibody but never after complement-mediated phagocytosis. Disruption of host autophagy in vitro by RNA interference against ATG5 (autophagy-related 5) decreased the phagocytosis of C. albicans and the …


The Role Of Comparative Effectiveness Research In Medicine And Health, Aisling R. Caffrey Sep 2012

The Role Of Comparative Effectiveness Research In Medicine And Health, Aisling R. Caffrey

Pharmacy Practice and Clinical Research Faculty Publications

No abstract provided.


A Ten-Year Experience Of A Pharmacist Consulting Team For Statewide Bioterrorism And Emergency Preparedness, Brett Feret, P. Bratberg Sep 2012

A Ten-Year Experience Of A Pharmacist Consulting Team For Statewide Bioterrorism And Emergency Preparedness, Brett Feret, P. Bratberg

Pharmacy Practice and Clinical Research Faculty Publications

No abstract provided.


Peaks Island Star : September 2012, Vol. 32, Issue 9, Service Agencies Of The Island Sep 2012

Peaks Island Star : September 2012, Vol. 32, Issue 9, Service Agencies Of The Island

Peaks Island Star, 2012

The Peaks Island Star is the newsletter of the island's service agencies and other community news.


Psci 530.01: Graduate Seminar In International Relations, Karen R. Adams Sep 2012

Psci 530.01: Graduate Seminar In International Relations, Karen R. Adams

University of Montana Course Syllabi

No abstract provided.


Psci 471.01: American Constitutional Law, James J. Lopach Sep 2012

Psci 471.01: American Constitutional Law, James J. Lopach

University of Montana Course Syllabi

No abstract provided.


Psci 341.01: Political Parties And Elections, Robert P. Saldin Sep 2012

Psci 341.01: Political Parties And Elections, Robert P. Saldin

University of Montana Course Syllabi

No abstract provided.


Hsta 141h.01b: Introduction To African-American Studies, Tobin Shearer Sep 2012

Hsta 141h.01b: Introduction To African-American Studies, Tobin Shearer

University of Montana Course Syllabi

No abstract provided.


How Does Stability In Financial Openness Affect Growth?, Erhan Aslanoglu, Pinar Deniz Sep 2012

How Does Stability In Financial Openness Affect Growth?, Erhan Aslanoglu, Pinar Deniz

Topics in Middle Eastern and North African Economies

No abstract provided.


Assessing The Preliminary Impacts Of The Libya's Crisis On The Tunisian Economy, Emanuele Santi, Saoussen Ben Romdhane, Mohamed Safouane Benaïssa Sep 2012

Assessing The Preliminary Impacts Of The Libya's Crisis On The Tunisian Economy, Emanuele Santi, Saoussen Ben Romdhane, Mohamed Safouane Benaïssa

Topics in Middle Eastern and North African Economies

No abstract provided.


Determinants Of Private Saving And Interaction Between Public & Private Savings In Turkey, Eser Pirgan Matur, Ali Sabuncu, Sema Bahçeci Sep 2012

Determinants Of Private Saving And Interaction Between Public & Private Savings In Turkey, Eser Pirgan Matur, Ali Sabuncu, Sema Bahçeci

Topics in Middle Eastern and North African Economies

No abstract provided.


A Study Of The Socioeconomic Determinants Of The Performance Of The New Lands Cooperatives, Ashraf S.E. Saleh Sep 2012

A Study Of The Socioeconomic Determinants Of The Performance Of The New Lands Cooperatives, Ashraf S.E. Saleh

Topics in Middle Eastern and North African Economies

No abstract provided.


The Arab Spring In The Mena Region: It Is Not The Economy!, José García Montalvo Sep 2012

The Arab Spring In The Mena Region: It Is Not The Economy!, José García Montalvo

Topics in Middle Eastern and North African Economies

No abstract provided.


Can Productivity Increases Really Explain The Lira Appreciation: Questions For The Central Bank Of The Republic Of Turkey, Kenan Lopcua, Almila Burgacb, Fikret Dulger Sep 2012

Can Productivity Increases Really Explain The Lira Appreciation: Questions For The Central Bank Of The Republic Of Turkey, Kenan Lopcua, Almila Burgacb, Fikret Dulger

Topics in Middle Eastern and North African Economies

No abstract provided.