Digital Commons Network^™

An Ecotoxicological Assessment Of The Impacts Of Chronic Exposure To Metals And Radionuclides On Marine Mussels: Relating Genotoxicity To Molecular And Organism-Level Effects, Lorna Jane Dallas

School of Biological and Marine Sciences Theses

Metals and radionuclides are environmentally relevant contaminants, yet their potential impacts on marine organisms have not been adequately evaluated. This is especially true for exposures of longer duration and/or lower contaminant concentration (i.e. chronic) which are often more representative of real world scenarios. In this context, a suite of biomarkers at different levels of biological organisation were investigated in an ecologically relevant bivalve species, Mytilus galloprovin- cialis after exposure to nickel (a metal), zinc pyrithione (an organometal) and tritiated water (a radionuclide). These contaminants were chosen based on their differing properties, and hence, mechanisms of action. All three contaminants produced …

Learning Medical Alarms Whilst Performing Other Tasks., Judy Edworthy, Christina Meredith, Elizabeth Hellier, David Rose

School of Psychology

UNLABELLED: Two studies are reported which first observe, and then attempt to replicate, the cognitive demands of intensive care unit (ICU) activity whilst concurrently learning audible alarms. The first study, an observational study in an ICU ward, showed that the alarms are very frequent and co-occur with some activities more than others. The three most frequently observed activities observed in the ICU were drugs (calculation, preparation and administration), patient observation and talking. The cognitive demands of these activities were simulated in a second, laboratory-based experiment in which alarms were learned. The results showed that performance in the alarm task generally …

Numerical Modelling For Hydrodynamic Impact And Power Assessments Of Tidal Current Turbine Arrays, Thomas Roc

School of Biological and Marine Sciences Theses

Channel constrictions in which strong currents are mainly driven by tidal processes represent sites with high potential for harvesting renewable and predictable tidal stream energy. Tidal Current Turbines (TCTs) deployed in arrays appear to be the most promising solution to efficiently capturing this carbon neutral energy resource. However to ensure the sustainable character of such projects, the balance between power extraction maximization and environmental impact minimization must be found so that device layout optimization takes into account environmental considerations. This is particularly appropriate since both resource and impact assessments go intrinsically hand in hand. The present method proposes the use …

Understanding Sediment Mobilisation Under Plunging Waves Within A Gravel Beach, Ian Phillip Ball

School of Biological and Marine Sciences Theses

Numerical modelling currently cannot accurately reproduce the onshore-offshore transport asymmetry observed on gravel beaches. The role of the impulsive pressure response generated by plunging waves has been hypothesised to aid mobilisation of sediment, and thus may contribute to transport asymmetry. This process is not currently included in models. Laboratory tests were conducted across a range of wave conditions to investigate the role of plunging wave-breaker impacts on the mobilisation of sediment of gravel beaches. Pressure records were obtained at positions close to the plunging impact locations, to monitor the localised pressures that lead to sediment mobilisation. The correction of the …

Pain Solutions In The Emergency Setting (Pasties); A Protocol For Two Open-Label Randomised Trials Of Patient-Controlled Analgesia (Pca) Versus Routine Care In The Emergency Department, Je Smith, M Rockett, R Squire, Cj Hayward, Et Al

Peninsula Medical School

Introduction Pain is the commonest reason that patients present to an emergency department (ED), but it is often not treated effectively. Patient controlled analgesia (PCA) is used in other hospital settings but there is little evidence to support its use in emergency patients. We describe two randomised trials aiming to compare PCA to nurse titrated analgesia (routine care) in adult patients who present to the ED requiring intravenous opioid analgesia for the treatment of moderate to severe pain and are subsequently admitted to hospital. Methods and analysis Two prospective multi-centre open-label randomised trials of PCA versus routine care in emergency …

An Educational Framework For Managing And Supporting Medication Adherence In Europe, S White, W Clyne, C Mshelia

Peninsula Medical School

Introduction: Decisions about taking medicines ultimately lie with patients, so health professionals need to engage with patients to manage and support medication adherence. Health professionals need appropriate education to do this. We aimed to develop an educational framework for health professionals in Europe for managing and supporting medication adherence. Description of the framework: The resulting educational framework comprises a competency framework, a curriculum, a diagnostic tool for competence assessment and a reading list. Quality assurance: Framework development started from a 2007 competency framework for shared decision-making. A literature review and a Europe-wide consultation were conducted and the ABC research team …

Plymouth Families Project Evaluation 2012, Z James

School of Law, Humanities and Social Sciences

No abstract provided.

Plymouth Family Intervention Project Longitudinal Review: 2008-2013, Z James, T Green

School of Law, Humanities and Social Sciences

No abstract provided.

Employability And Transferable Skills: Investigating Work Placements For Humanities Students, Sandra Barkhof, C Rockey

School of Law, Humanities and Social Sciences

This project aims to enhance the employability of our graduates through an evaluative case study investigating subject-specific work placement and work experience opportunities in the local and regional community. The project will use a new work-facing module on ‘History and Heritage’ as a case study, although the aim of the project is to provide a sustainable model for a work-facing approach to teaching that can also be applied to other subjects.In the past, History as a course has offered no work placements or work experience either as part of the curriculum or as extra-curricular activities. Preliminary research has shown that …

The Evaluation Of A Biometric-Based Identification System For Remote-Based Exam Invigilation, Nathan Clarke, Paul Dowland, Steve Furnell

School of Engineering, Computing and Mathematics

To critically evaluate the technology options available for a continuous biometric-based identification system. To design and implement a continuous biometric-based identification system for use within e-learning. The prototype will be independent but built around the University’s current Perception system in the first instance. To evaluate the operational characteristics of the system and the human-factors of acceptance, usability and privacy, and disseminate the system across the University. To investigate the pedagogical factors underpinning this new area of e-assessment. Prior research has raised concerns regarding information security in e-learning systems for over a decade now (Littman, 1998). However, in reality much more …

Modeling Speech Imitation And Ecological Learning Of Auditory-Motor Maps, C Canevari, L Badino, A D'Ausilio, L Fadiga, G Metta

School of Engineering, Computing and Mathematics

Classical models of speech consider an antero-posterior distinction between perceptive and productive functions. However, the selective alteration of neural activity in speech motor centers, via transcranial magnetic stimulation, was shown to affect speech discrimination. On the automatic speech recognition (ASR) side, the recognition systems have classically relied solely on acoustic data, achieving rather good performance in optimal listening conditions. The main limitations of current ASR are mainly evident in the realistic use of such systems. These limitations can be partly reduced by using normalization strategies that minimize inter-speaker variability by either explicitly removing speakers' peculiarities or adapting different speakers to …

Event-Driven Visual Attention For The Humanoid Robot Icub, F Rea, G Metta, C Bartolozzi

School of Engineering, Computing and Mathematics

Fast reaction to sudden and potentially interesting stimuli is a crucial feature for safe and reliable interaction with the environment. Here we present a biologically inspired attention system developed for the humanoid robot iCub. It is based on input from unconventional event-driven vision sensors and an efficient computational method. The resulting system shows low-latency and fast determination of the location of the focus of attention. The performance is benchmarked against an instance of the state of the art in robotics artificial attention system used in robotics. Results show that the proposed system is two orders of magnitude faster that the …

An Assessment Of Current Methodologies For Mitigating The Potential Effects Of Anthropogenic Underwater Sound On Marine Life, And Recommendations For Best Practice, Ross Craig Compton

School of Biological and Marine Sciences Theses

Underwater sound from anthropogenic sources such as seismic surveys, marine renewable device installations and naval exercises has the potential to disturb and cause injury to a variety of marine species. There is particular concern for the potential effects upon marine mammals, which utilise sound to communicate, hunt and navigate. Observed effects include behavioural changes and reduced sighting rates, with unknown consequences for individuals or populations over time. Potential effects on marine mammals include sound induced damage to auditory systems, altered diving behaviour potentially resulting in decompression sickness, stranding and death. The aim of the thesis was to develop a framework …

Evidence-Based Programs In Children's Services: A Critical Appraisal, Nick Axford, Louise Morpeth

Peninsula Medical School

No abstract provided.

Inclusion Of Lupin Meal And Effect Of A Commercial Feed Supplement (Synergen™) In Diets For Carp, Cyprinus Carpio, Ayub Anwar

School of Biological and Marine Sciences Theses

Abstract Plant proteins are mainly used to formulate diets for carp. Soybean meal (SBM) is one of the most nutritious of all plant protein sources in carp feeds. However, an increase in the use of soybean meal for human consumption and animal feed in both developed and developing countries has resulted in an increase market price of soybean meal globally. Therefore, using other inexpensive plant protein sources in carp feeds would be beneficial to reduce feed cost and contribute to food security as well as to sustain aquaculture production. Anti-nutritional factors (ANFs) are believed to be the most important factors …

Δ9-Tetrahydrocannabinol Is Protective Through Pparγ Dependent Mitochondrial Biogenesis In A Cell Culture Model Of Parkinson's Disease., Ml Zeissler, J Eastwood, Hanemann C Oliver, J Zajicek, C Carroll

Peninsula Medical School

Cannabinoids such as Δ9-tetrahydrocannabinol (Δ9-THC) are neuroprotective in animal and cell culture models of Parkinson's disease (PD). In a PD cell culture model we recently demonstrated that Δ9-THC is neuroprotective through activation of the nuclear receptor peroxisomal proliferator-activated receptor γ (PPARγ). Furthermore, activation by specific agonists rosiglitazone and pioglitazone, has also been found neuroprotective. PPARγ is a nuclear receptor whose activation can lead to the expression of proteins involved in the de novo synthesis of mitochondria. One such protein is the PPARγ co-activator 1 α (PGC1α) as it co-activates NRF-1 mediated gene expression which is essential for the production of …

Religious Faith And Transformational Processes In Marriage, Michael A. Goodman, David C. Dollahite, Loren D. Marks, Emily Layton

Faculty Publications

Leading scholars of marital processes strongly recommend supplementing the current focus on marital conflict to include research on transformative processes. This qualitative study examines the connection between religion and the transformative processes of commitment and coping in marriage. The sample for this study includes 184 married couples (N = 368 individuals), making it far larger than most in-depth, qualitative interview-based studies. Participants included Christians, Jews, and Muslims with an over sampling of minorities and immigrant families living in all eight regions of theUnited States. For several decades studies have shown a largely positive correlation between (a) religiosity and marital commitment …

A Dynamic Perspective On Affect And Creativity, Ronald Joachim Bledow, K. Rosing, M. Frese

Research Collection Lee Kong Chian School Of Business

We argue that creativity is influenced by the dynamic interplay of positive and negative affect: High creativity results if a person experiences an episode of negative affect that is followed by a decrease in negative affect and an increase in positive affect, a process referred to as an “affective shift.” An experience-sampling study with 102 full-time employees provided support for the hypotheses. An experimental study with 80 students underlined the proposed causal effect of an affective shift on creativity. We discuss practical implications for facilitating creativity in organizations.

Homing : Poetry ; &, An Essay On The Poetic Leap In The Late Work Of R.S. Thomas, Shevaun Cooley

Theses: Doctorates and Masters

Homing, as a collection, speaks to the capacity and yearning to navigate our way towards something we might call home. In animal behaviour, this seems like an instinct, hard-wired to the body. It is something I envy. By comparison, the instinct, in human behaviour, feels muffled and complicated.

These poems move between two places in which I feel ‘at home’, whatever that means: the south-west of Western Australia, where I was born and raised, and the north-west of Wales, where I lived for a time, and find myself returning to, drawn not by blood, but by longing, and a deep …

My Worst Ever Night At The Best School Ball Ever : Creating Taboo Theatre For Teenagers, Jeremy F. Rice

Theses: Doctorates and Masters

My Worst Ever Night at the Best School Ball Ever (School Ball) is a new play for teenage audiences. The action takes place on the night of a ball for final year students. A prank with a goat goes horribly wrong, a photo of a girl pissing in a pot plant is widely circulated, and everyone finds out about the boy in a sexual relationship with a teacher. At the heart of the play are teenagers, armed with mobile phones, trying to find their way in a contradictory and confusing world.

The creative development of School Ball centred on practice-based …

The Identification Of Diagnostic Serological Autoantibodies For Cutaneous Melanoma, Pauline Zaenker

Theses: Doctorates and Masters

Abstract not available.

School Administrators' Beliefs Regarding The Relationship Between School Improvements And Formal School Registration, Harm P. Witten

Theses: Doctorates and Masters

In 2004, the Government of Western Australia introduced an inspection-type formal school registration process for Non-Government (Independent) Schools, fulfilling the legislative requirement of a new School Education Act of 1999 (Part 4, Sec.159). This formal school registration process featured twelve criteria that are used to evaluate the quality of education. The government claimed that it would ensure a good education for all students in Western Australian, including those students enrolled in Independent Schools. However, very little is known about this formal school registration process, the twelve criteria used in it, or even if school administrators believe that it has helped …

The Biology And Ecology Of Epinephilidae Speciea And Their Implications To Fisheries Management, Jason R. How

Theses: Doctorates and Masters

This thesis examines the biological and ecological aspects of members of the globally exploited Epinephilidae with reference to fisheries management and in particular the use of closures. The leopard coralgrouper Plectropomus leopardus is a common reef fish throughout the Indo-Pacific region and a major target of both commercial and recreational fisheries. There has been limited research on this species in the eastern Indian Ocean, where there are only two populations. An examination of the species found a number of significant biological differences to their eastern Australian con-specifics. Most noticeable was the strong size-related cue over their protogynous sex change. The …

Magnetocardiography In Unshielded Environment Based On Optical Magnetometry And Adaptive Noise Cancellation, Valentina Tiporlini

Theses: Doctorates and Masters

This thesis proposes and demonstrates the concept of a magnetocardiographic system employing an array of optically-pumped quantum magnetometers and an adaptive noise cancellation for heart magnetic field measurement within a magnetically-unshielded environment.

Optically-pumped quantum magnetometers are based on the use of the atomic-spin-dependent optical properties of an atomic medium. An Mxconfiguration- based optically-pumped quantum magnetometer employing two sensing cells containing caesium vapour is theoretically described and experimentally developed, and the dependence of its sensitivity and frequency bandwidth upon the light power and the alkali vapour temperature is experimentally demonstrated. Furthermore, the capability of the developed magnetometer of measuring very weak …

Applying The Principles Of Spatial Modelling To The Management Of Biodiversity In The Fragmented Landscapes Of South-Western Australia, Shaun Molloy

Theses: Doctorates and Masters

Biodiversity conservation throughout the world is challenged by the impacts of a changing climate on fragmented landscapes. To mitigate these threats, conservation managers require models which can demonstrate the consequences of both negative impacts and management actions. This need can be addressed through spatial modelling applications. Unfortunately, throughout much of the world, spatial modelling is forgone, being seen as requiring skills and resources beyond the means of many conservation planners and managers. This thesis seeks to address this dilemma by delivering criteria for a successful modelling application and by providing case studies which demonstrate how appropriate modelling can be undertaken …

Pax3 Expression, Protein Modifications And Downstream Target Gene Profiling In Melanocytes And Melanoma Cells, Danielle Bartlett

Theses: Doctorates and Masters

PAX3 is a transcription factor. It plays a major role in the development of melanocytes in the embryo. As a result of alternative splicing, the gene gives rise to eight different transcripts which encode proteins that have differing structures and are therefore likely to activate different downstream target genes. The presence of post-translational modifications has also been shown to alter the functions of the proteins.

PAX3 regulates the maintenance of undifferentiated melanoblasts and mediates pathways involved in proliferation, migration and survival. It has been shown to be expressed in melanoblasts, adult melanocytes, naevi and in most melanoma cells. This implies …

Opto-Vlsi-Based Adaptive Optical Power Splitter/Combiner For Next Generation Dynamic Optical Telecommunication Networks, Haithem A. Mustafa

Theses: Doctorates and Masters

The demand for optical power splitters is growing globally, due to the rapid deployment of fibre-to-the-premises, optical metropolitan area network (MAN), and active optical cables for TV/Video signal transport. Optical splitters play an important role in passive optical network (PON) technology by enabling several hundred users to share one optical line terminal. However, current PONs, which use fixed optical power splitters, have limited reconfigurability particularly in adding/dropping users to/from an optical network unit.

An adaptive optical power splitter (OPS) can dynamically reallocate the opticalpower in the entire network according to the real-time distribution of users and services, thus providing numerous …

Implementing A Reggio Emilia Inspired Approach In A Mainstream Western Australian Context: The Impact On Early Childhood Teachers' Professional Role, Claire Hall

Theses: Doctorates and Masters

Reggio Emilia, an approach to early childhood that was developed in a Northern Italian city of the same name, is highly regarded as acknowledged by educators and researchers world-wide (Gandini, 1993). The Reggio Emilia philosophy is distinguished by the presentation of an image of children as being strong, rich and powerful learners (Hendricks, 2004; Millikan, 2003). This approach is marked as being adopted and adapted to suit particular cultural and educational settings. These situation sensitive approaches are noted as being Reggio Emilia inspired.

This qualitative case study investigated how the professional role of four early childhood teachers was impacted by …

Factors Influencing The Incidence Rates Of Injuries And Accidents Among Seafarers And Rig Workers Providing Support To The Wa Offshore Oil And Gas Industry, Tony Martinovich

Theses: Doctorates and Masters

The aim of this study was to identify, discuss and make recommendations regarding causal factors associated with injuries and accidents among seafarers and rig workers providing support to the WA offshore oil and gas industry. These incidents cause significant personal and economic burdens for employees, employers and the community in general.

A sample of 484 participants were recruited from a workforce of 9800 employees (approximately 5%). Participants were stratified into 2 cohorts; those who had suffered injury (286 – study group) and those who had not (198 - controls).

Data from the study group were stratified into oilrig workers and …

Pictures In Words : Indexing, Folksonomy And Representation Of Subject Content In Historic Photographs, Brian Stewart

Theses: Doctorates and Masters

Subject access to images is a major issue for image collections. Research is needed to understand how indexing and tagging contribute to make the subjects of historic photographs accessible.

This thesis firstly investigates the evidence of cognitive dissonance between indexers and users in the way they attribute subjects to historic photographs, and, secondly, how indexers and users might work together to enhance subject description. It analyses how current indexing and social tagging represent the subject content of historic photographs. It also suggests a practical way indexers can work with taggers to deal with the classic problem of resource constraints and …