Digital Commons Network^™

Fd&C Red Dye No. 40 (Allura Red) Effects On Non-Human Animal Testing: A Systematic Review, Vilate Winfrey

Honors Theses

Artificial food dye is added to foods to enhance their color and appearance for consumers. This systematic review aims to review the literature on Red Dye No. 40 and its effects on non-human animals. Studies were included if (a) exposure to Red Dye No. 40 was the independent variable, (b) nonhuman animals were the subjects, and (c) at least one behavioral, neurological, or physiological dependent variable was reported. An article search was conducted with Scopus Elsevier. An abstract review was conducted to determine whether the articles met all inclusion criteria. The author conducted a multi-stage application of inclusion criteria to …

Truly We Speak Podcast - Creative Thesis Project: "Uplifting Faith, Community, And Education Through The Voice Of The People.", Sierra Ward

Honors Theses

This creative thesis has been curated by Sierra Ward, a Sales and Marketing student at Western Michigan University. The intent behind this project was to combine shared interests between Faith, Community, and education to create a podcast, interviewing prominent members of the community, in hopes of inspiring others to “speak truly” and use their voice to evoke everlasting change. A wide range of guest were chosen to have authentic conversations with the purpose of educating the audience about real life situations. The filming of this project started in Fall of 2024 and concluded in the Spring of 2025.

Growing up …

How Bats View Their Flowers: Exploring The Use Of Visual Floral Cues By Nectarivorous Neotropical Bats, Lindsey R. Dennison

Theses

Neotropical nectar bats in cloud forest ecosystems must navigate and forage in dark, complex landscapes containing an incredible diversity of flowering plants. Despite these challenges, nectar bats are extremely successful at exploiting nectar resources from plants. Much of the sensory ecology behind these bat-plant interactions has been investigated and we know from previous studies that echolocation and olfaction are critical sensory modalities to nectar bats. Echo-acoustically conspicuous floral and vegetative structures as well as sulfur-containing volatile compounds function as signals, allowing bats to sense plants. However, not all plants exhibit conspicuous echo-acoustic and/or olfactory characteristics. Furthermore, many neotropical bat-pollinated plants …

The Psychological Effects Of Ice Conditions In Long-Term Space Travel, Jamen W. Barker

Student Works

The psychological effects of long durations spent in space remain largely unexplored, as do potential treatments for these effects. This review compiled data from 19 articles found via searches on the APAPsychInfo and Google Scholar databases, as well as a few ancillary sources. These studies are relevant to the study of the psychological effects of space travel and isolated, confined, or extreme (ICE) environments, and research into means of addressing them, as well as limitations in current literature on the topic. Studies found sleep deprivation, largely due to microgravity, to be a contributing factor to increased stress in space. Social …

Eny Development Llc V. Sneed

All Decisions

In this nonpayment proceeding involving a LIHTC-regulated apartment, the tenant invoked protections under the CARES Act to contest the landlord's claim. The tenant moved to dismiss based on federal notice requirements for properties receiving federal subsidies. The court found that the CARES Act applied, drawing persuasive authority from Sherwood Auburn LLC v. Pinzon and Arvada Vill. Gardens PL v. Garate, which clarified that LIHTC properties are covered by the statute's protections. Concluding the landlord failed to meet the Act's 30-day notice prerequisite, the court granted the tenant's motion. Practice note: In nonpayment cases involving subsidized housing, practitioners must evaluate CARES …

Learning By Confusion: The Phase Diagram Of The Holstein Model, George Issa, Owen Bradley, Ehsan Khatami, Richard Scalettar

Faculty Research, Scholarly, and Creative Activity

We employ the "learning by confusion"technique, an unsupervised machine learning approach for detecting phase transitions, to analyze quantum Monte Carlo simulations of the two-dimensional Holstein model - a fundamental model for electron-phonon interactions on a lattice. Utilizing a convolutional neural network, we conduct a series of binary classification tasks to identify Holstein critical points based on the neural network's learning accuracy. We further evaluate the effectiveness of various training datasets, including snapshots of phonon fields and other measurements resolved in imaginary time, for predicting distinct phase transitions and crossovers. Our results culminate in the construction of the finite-temperature phase diagram …

Optimizing Epoxy Nanocomposites With Oxidized Graphene Quantum Dots For Superior Mechanical Performance: A Molecular Dynamics Approach, Prathamesh P. Deshpande, Robert Chan-Jobe, Josh Kemppainen, Gregory M. Odegard, Ozgur Keles

Faculty Research, Scholarly, and Creative Activity

Due to their excellent mechanical properties, epoxy composites are widely used in low-density applications. However, the brittle epoxy matrix often serves as the principal failure point. Matrix enhancements can be achieved by optimizing polymer combinations to maximize intermolecular interactions or by introducing fillers. While nanofillers such as clay, rubber, carbon nanotubes, and nanoplatelets enhance mechanical properties, they can lead to issues like agglomeration, voids, and poor load transfer. Quantum dots, being the smallest nanofillers, offer higher dispersion and the potential to promote intermolecular interactions, enhancing stiffness, strength, and toughness simultaneously. This study employed molecular dynamics simulations to design graphene quantum …

Analysis Of Nitrogen Accumulation And Gene Expression In Hydroponically-Grown Chenopodium Genotypes, Teal Kalt

Theses and Dissertations

Nitrogen (N) is an essential macronutrient required by all plants to complete their life cycles. Inefficient N uptake contributes to over fertilization and subsequent environmental and sustainability issues resulting in the need for improved nitrogen use efficiency (NUE). Chenopodium quinoa is a resilient pseudocereal crop that is relatively adapted to N-deficient soils. Previous studies have uncovered the unique genetic structure of quinoa and its physiological responses to N availability; however, gaps remain in understanding its molecular mechanisms for NUE. This study investigates four quinoa genotypes (Real-1, 0654, KU-2, and QQ74) hydroponically grown in N-deficient conditions. RNA sequencing (RNA-seq) analysis identified …

Acute Pain Treatment In Patients With Sickle Cell Disease Transitioned To Buprenorphine: Evidence Of Equivalent Pain Relief, Christopher P. Carroll, Elizabeth J. Prince, Ashley P. Lauriello, Lydia H. Pecker, Sophie M. Lanzkron

Cardeza Foundation for Hematologic Research

Objectives Buprenorphine is a novel opioid analgesic with complex receptor pharmacology. It is safer than high dose chronic treatment with full agonist opioids. However, buprenorphine can inhibit conventional opioids, complicating acute pain treatment. Methods We compare acute pain treatment outcomes in 55 sickle cell disease patients in the year before and after transition to buprenorphine. Infusion center visits, ED visits, and hospital admissions were compared before and after transition, and pain outcomes were compared using linear mixed effects models with patients entered as random effects to account for differential contribution to the outcomes by visit rates. Results Acute care visits …

Developing Adaptive Expertise To Support All Learners: An Autoethnographic Investigation Of My Teaching Journey, Jennifer Zacuto

LMU Theses and Dissertations

Entering the profession with vastly different preparation and perspectives, teachers encounter diverse students, complex contexts, and shifting expectations for which they frequently find themselves underprepared by their preservice training. With greater awareness emerging about the significant effect that individual teachers have on student outcomes, and an understanding that the knowledge and mindsets needed for optimal instruction cannot be fully developed during preservice education, teachers need effective paths for ongoing professional development (PD). Self-directed PD, with its capacity for customization in content and pacing, has the potential to more effectively foster meaningful and continuous teacher learning. Through autoethnographic methods (e.g., Adams …

Existence Of Bounded Asymptotic Solutions Of Autonomous Differential Equations, Minh Van Nguyen Dr., Vu Trong Luong, William Barker, Duchuy Nguyen

Faculty Scholarship

We study the existence of bounded asymptotic mild solutions to evolution equations of the form u′(t)=Au(t)+f(t),t≥0in a Banach space X, where Agenerates an (analytic) C0-semigroup and fis bounded. We fifind spectral conditions on Aand ffor the existence and uniqueness of asymptotic mild solutions with the same as that of f. In the resonance case, a sufficient condition of Massera type theorem is found for the existence of bounded solutions with the same profifile as f. The obtained results are stated in terms of spectral properties of Aand f, and they are analogs of classical results of Katznelson-Tzafriri and Massera for …

Unh Student Awarded Prestigious Graduate Fellowship, Sarah Schaier

UNH Today Archive

No abstract provided.

Kidder Award Recipients Recognized At Annual Pride And Pancakes Celebration, Jeremy Gasowski

UNH Today Archive

No abstract provided.

White Matter Integrity Of Hearing And Cognitive Impairments In Healthy Aging, Samaneh Nemati, Meisam Arjmandi M.Sc., Ph.D., Jean Neils-Strunjas Ph.D, Ccc-Slp, Roger Newman-Norlund Ph.D., Sarah Newman-Norlund B.S., M.A., Laura Droege, Leonardo Bonilha, Julius Fridriksson Ph.D.

Faculty Publications

Age-Related Hearing Loss (ARHL), or presbycusis, affects two-thirds of U.S. adults over 70 and is linked to cognitive decline and an increased risk of dementia. This study examines associations between white matter integrity and hearing and cognitive function in healthy aging using diffusion tensor imaging (DTI). We recruited 126 participants (92 female) aged 20–79 years () from the Aging Brain Cohort Study at the University of South Carolina (ABC@UofSC). Cognitive performance was assessed using the Montreal Cognitive Assessment (MoCA), and hearing was evaluated through pure-tone thresholds (PTT) and words-in-noise (WIN) thresholds. White matter integrity was measured with fractional anisotropy (FA) …

Aesthetics In Instructional Design, Dennis M. West

Theses and Dissertations

This multi-article dissertation examines how aesthetics enhances instructional design to foster engaging, transformative learning experiences. Despite its potential, aesthetics is often granted a secondary status in design practice, being seen as less important than functionality. The first article explores philosopher Monroe Beardsley's five aesthetic criteria--object-directedness, felt freedom, detached affect, active discovery, and wholeness--through a theoretical literature review, proposing their application to elevate learner engagement and interest. The second article, a qualitative investigation, analyzed the Cybermatics Playable Case Study (PCS; a cybersecurity simulation) from the perspective of Beardsley's aesthetic criteria. This investigation involved four students and two designers interviewed hermeneutically over …

Analysis Of Radial Inlet Distortion On Transonic Fan Performance, Tyler M. Reedy

Theses and Dissertations

Improving fan design and performance prediction requires an understanding of the impacts of inlet distortions. Inlet distortion describes any non-uniform distribution in the flow, usually referring to deviations in pressure and temperature. Using full annulus Unsteady Reynolds-Averaged Navier Stokes (URANS) simulations, the effects of both hub and tip radial distortions on the Air Force Research Lab (AFRL) Rotor 4 fan are analyzed. Overall performance, total pressure (Pt) distortion transfer, and total temperature (Tt) distortion generation are presented and compared for three operating points: near-stall, design, and choke. Hub radial inlet distortion magnitudes of 15% and 20%, and a tip radial …

Data Quality And Enterprise Architecture: An Analysis Of The Awareness And Knowledge Of Data Quality Artifacts, Principles, Practices, And Application In Enterprise Architecture, Jason Alan Minton

Theses and Dissertations

Enterprise Architecture (EA) is a discipline, approach, and practice that aims to align the enterprise’s technical infrastructure, strategy, processes, and technology investments with the organization’s strategy to fulfill the mission and vision. Data quality is conformance to data specifications (Talburt, 2015, p. 192), and low data quality has significant implications for decisions and outcomes across the enterprise. Scant literature and research exist surrounding the intersection, integration, and impact of data quality within EA practices. This research examines the awareness and understanding of Enterprise Architect and Technology Architect populations regarding data quality concepts, artifacts, and tools. The research aims to answer …

Evaluating The Potential For Reusing Process Waste Fiber, Elisha Ewing

Honors Theses

This study was born out of curiosity around the potential use of reject materials from the papermaking screening system for molded fiber product development. The team sought to explore the technical feasibility of this concept and develop a proposed design for mill implementation. The project supports the common papermaking objective of reducing fiber loss from the stock preparation process.

The project assessed first the technical feasibility through laboratory testing and trials. The team dedicated time to characterizing screen reject samples from local mills and running trials using the good fibers extracted from the samples. Molded fiber products were successfully created …

The Psychological Effects Of Childhood Trauma On Adult Relationships, Anna B. Dunford

Student Works

This literature review explores the long-term psychological effects of childhood trauma on adult relationships. Drawing on empirical studies and theoretical frameworks such as attachment theory and the intergenerational transmission of trauma, the review uses findings from recent research on how adverse childhood experiences (ACEs) shape adult relationship dynamics. Through a mixed-methods approach, electronic searches were conducted using databases such as PsycINFO, PubMed, and Google Scholar to identify relevant literature on the psychological effects of childhood trauma on adult relationships. Specifically, the paper examines three interconnected domains: attachment styles, emotional regulation, and relationship satisfaction. The reviewed literature reveals a consistent association …

Coping With Distress In Athletes: Strategies And Barriers, Julianna Cheney

Student Works

Cognitive techniques and mental strategies are utilized by athletes to enhance performance in their sport, particularly when it comes to managing physical distress or discomfort. This literature review aims to both compile the most current literature on the cognitive strategies athletes implement to counter physical distress, as well as address the mental barriers they may face. Searches conducted in Google Scholar and PsycINFO as well as articles drawn from the reference sections of chosen articles yielded a total of 11 peer reviewed articles related to the main focus of this literature review. Within the available literature on mental strategies,, there …

Perinatal Mood And Anxiety Disorders (Pmads): A Scoping Review, Christina Willis Bsn, Rn, Nia Wells Bsn, Rn, Miranda Smith Bsn, Rn, Kate Fouquier Cnm, Phd, Facnm

Doctor of Nursing Practice Projects

Purpose/Background Perinatal Mood and Anxiety Disorders (PMADs), including postpartum depression, anxiety, and psychosis, significantly impact maternal and infant health. This scoping review consolidates current literature on PMADs, emphasizing prevalence, risk factors, screening, and treatment. The primary aim is to identify research gaps and inform clinical guidelines to enhance perinatal care.

Methods A literature search followed PRISMA guidelines from August 2022 to November 2024. Databases searched included PubMed, CINAHL, Scopus, and Google Scholar, using terms such as "perinatal mood disorders" and "maternal mental health." Inclusion criteria were English-language studies from the past decade addressing PMADs during pregnancy and up to one …

Mri Distance Measures As A Predictor Of Subsequent Clinical Status During The Preclinical Phase Of Alzheimer's Disease And Related Disorders, Xinyi Zhang, John C Morris, Tammie L S Benzinger, Et Al.

2020-Current year OA Pubs

Brain atrophy over time, as measured by magnetic resonance imaging (MRI), has been shown to predict subsequent cognitive impairment among individuals who were cognitively normal when first evaluated, indicating that subtle brain atrophy associated with Alzheimer's disease (AD) may begin years before clinical symptoms appear. Traditionally, atrophy has been quantified by differences in brain volume or thickness over a specified timeframe. Research indicates that the rate of atrophy varies across different brain regions, which themselves exhibit complex spatial and hierarchical organizations. These characteristics collectively emphasize the need for diverse summary measures that can effectively capture the multidimensional nature of degeneration. …

Do Pro-Environmental Factors Lead To Customers’ Purchase Intention Of Home Energy Management System? The Moderating Effects Of Energy-Efficient Habits, Maryam Zidehsaraei, Minoo Zidehsaraei, Kourosh Esfandiar

Research outputs 2022 to 2026

Environmental challenges, encompassing climate change and global warming, compel consumers to alter their consumption habits. Although there has been a notable surge in consumer awareness regarding pro-environmental practices, especially concerning home energy, there remains a lack of comprehensive research exploring the factors affecting consumers’ willingness to adopt or invest in home energy management system (HEMS) technology. Notably, there have been no studies focused on the factors influencing HEMS purchase intentions (PI) in the Iranian context. Grounded in the theory of planned behavior (TPB) and the norm activation model, this research delves into the PI of Iranian households regarding HEMS, categorizing …

Distinguishing Multisystem Inflammatory Syndrome In Children From Typhus Using Artificial Intelligence: Mis-C Versus Endemic Typhus (Ai-Met), Kristiana Nasto, Flor M Munoz, Gordon E Schutze, Sridevi Devaraj, Eyal Muscal, Marietta M De Guzman, Kristen Sexson Tejtel, Tiphanie P Vogel, Ioannis A Kakadiaris

Faculty, Staff and Students Publications

Background: The pandemic emergent disease multisystem inflammatory syndrome in children (MIS-C) following coronavirus disease-19 infection can mimic endemic typhus. We aimed to use artificial intelligence (AI) to develop a clinical decision support system that accurately distinguishes MIS-C versus endemic typhus (MET).

Methods: Demographic, clinical, and laboratory features rapidly available following presentation were extracted for 133 patients with MIS-C and 87 patients hospitalized due to typhus. An attention module assigned importance to inputs used to create the 2-phase AI-MET. Phase 1 uses 17 features to arrive at a classification manually (MET-17). If the confidence level is not surpassed, 13 additional features …

Enhancing Emergency Department Communication: Structural Requirements And Outcomes Of Standardized Handover Processes, Bridgette A. Moss-Sherman

Walden Dissertations and Doctoral Studies

Effective communication during patient handovers is crucial for ensuring safe, quality care in the emergency departments (EDs) of small to medium-sized hospitals. The absence of standardized communication tools presents significant challenges, potentially leading to errors and hindering care coordination. This integrative review evaluates strategies for implementing standardized handover processes while examining their outcomes, underscoring the urgent need for enhanced communication practices. Grounded in the Donabedian quality conceptual framework, which encompasses structure, process, and outcomes as interconnected components of healthcare quality, the review identifies five key themes: (a) standardized communication protocols, advocating for the adoption of structured tools like SBAR and …

Staff Education For Nursing Staff, Tina Clarke Cherry

Walden Dissertations and Doctoral Studies

Executive Summary: Staff Education Project

A Screening Question To Assess Risk Of Using Antibiotics Without A Prescription: A Diagnostic Study, Marissa Valentine-King, Lindsey Laytner, Azalia Mancera, Roger Zoorob, Michael K Paasche-Orlow, Richard L Street, Barbara W Trautner, Larissa Grigoryan

Faculty, Staff and Students Publications

Objectives: Non-prescription antibiotic use (using antibiotics without medical advice) is potentially unsafe and promotes antimicrobial resistance. We studied predictors of prior non-prescription use and whether screening for prior non-prescription antibiotic use predicted intention of future non-prescription antibiotic use.

Methods: The survey was performed from January 2020 - June 2021 in six public primary care clinics and two private emergency departments. Prior non-prescription users were respondents who reported taking oral antibiotics for symptoms without contacting a clinician. Intended use was defined by answering yes to the question, "would you use antibiotics without contacting a doctor/nurse/dentist/clinic." We examined predictors for prior non-prescription …

Psychrotrophic Antarctic Marine Bacteria As Potential Reservoirs For Novel Antimicrobial Genes, Kudzai Hwengwere, Grant G. January, Kerry L. Howell, Lloyd S. Peck, Mathew Upton, Melody S. Clark

School of Biomedical Sciences

Antarctica is a very cold, isolated continent surrounded by frozen seas, yet these extreme environmental conditions have not restricted life and diversity in the sea. The marine environment is seasonally highly productive and harbours diverse and abundant communities of organisms, with many endemic species occurring nowhere else in the world. Such communities and their associated microbiomes are increasingly recognized as an unexplored source of novel antimicrobial products. Hence, the major aim of this study was to examine the antimicrobial potential of bacteria cultured from eight Antarctic marine invertebrate species, while gathering data on Antarctic microbial thermal and salinity tolerances. All …

Left Ventricular Entry To Reduce Brain Lesions During Catheter Ablation: A Randomized Trial, Trisha F Hue, Feng Lin, Jing Cheng, J Peter Weiss, Wendy S Tzou, Henry Hsia, Ashkan Ehdaie, Daniel H Cooper, T Jared Bunch, Jeffrey Arkles, Babak Nazer, Adam Lee, Alexios Hadjis, Duy T Nguyen, Mihail G Chelu, Joshua Moss, Jonathan C Hsu, Miguel Valderrábano, Prashant D Bhave, Andrew D Beaser, Arvindh Kanagasundram, Oussama Wazni, Jason Bradfield, Grace Wall, Kathleen Chang, Michelle Yang, Gabrielle Montenegro, Sabrina Jarrott, Joel H Kramer, Anthony S Kim, Yvonne M Morris, William P Dillon

Faculty, Staff and Students Publications

Background: Catheter ablation of ventricular arrhythmias, one of the most rapidly growing procedures in cardiac electrophysiology, is associated with magnetic resonance imaging-detected brain lesions in more than half of cases. Although a retrograde aortic approach is conventional, modern tools enable entry through a transseptal approach that may avoid embolization of debris from the arterial system. We sought to test the hypothesis that a transseptal puncture would mitigate brain injury compared with a retrograde aortic approach.

Methods: The TRAVERSE trial (Transseptal Versus Retrograde Aortic Ventricular Entry to Reduce Systemic Emboli) was a multicenter randomized controlled comparative effectiveness trial. Patients with left …

Cerebrospinal Fluid Proteomics Identification Of Biomarkers For Amyloid And Tau Pet Stages, Zhibo Wang, Yuhan Chen, Katherine Gong, Bote Zhao, Yuye Ning, Meilin Chen, Yan Li, Muhammad Ali, Jigyasha Timsina, Menghan Liu, Carlos Cruchaga, Jianping Jia

2020-Current year OA Pubs

Accurate staging of Alzheimer's disease (AD) pathology is crucial for therapeutic trials and prognosis, but existing fluid biomarkers lack specificity, especially for assessing tau deposition severity, in amyloid-beta (Aβ)-positive patients. We analyze cerebrospinal fluid (CSF) samples from 136 participants in the Alzheimer's Disease Neuroimaging Initiative using more than 6,000 proteins. We apply machine learning to predict AD pathological stages defined by amyloid and tau positron emission tomography (PET). We identify two distinct protein panels: 16 proteins, including neurofilament heavy chain (NEFH) and SPARC-related modular calcium-binding protein 1 (SMOC1), that distinguished Aβ-negative/tau-negative (A-T-) from A+ individuals and nine proteins, such as …