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Community-Engaged Learning In Geosciences At "Erwin Fish Hatchery", Rezaul Bari Ishan Apr 2025

Community-Engaged Learning In Geosciences At "Erwin Fish Hatchery", Rezaul Bari Ishan

Dr. Jay W. Boland Research Day

Since 2017, ETSU Principles of Hydrology course has included a 5-6 week-long field research project that engages students in an authentic field research experience with community partners. Building on this tradition, in October 2024, geosciences students from ETSU partnered with the Erwin National Fish Hatchery to meet the hatchery’s need for a detailed water quality assessment. They focused on two natural springs—critical water sources for hatchery operations—examining their hydrologic behavior and water quality, specifically whether they share an origin and how rainfall influences turbidity. Using ISCO water samplers, YSI probes, water level loggers, and turbidity meters, students tracked water levels …


Caregiver Adversity And Mental Health Predicting Children’S Healthy Psychosocial Functioning Data Are Fully Collected:, Emily Hatcher Apr 2025

Caregiver Adversity And Mental Health Predicting Children’S Healthy Psychosocial Functioning Data Are Fully Collected:, Emily Hatcher

Dr. Jay W. Boland Research Day

In this study we aimed to explore the impact of both caregiver and child adversity, alongside caregiver mental health, on children’s psychosocial outcomes. While existing literature highlights the role of childhood adversity in predicting later psychosocial difficulties, less is known about the combined influence of caregiver adversity and mental health on children’s functioning. Thus, this study aimed to investigate the relative contributions of caregiver adverse childhood experiences (ACEs), child ACEs, and caregiver anxiety and depression to children’s mental health, as measured by the Pediatric Symptoms Checklist (PSC-17). Data were collected from 148 caregivers (N = 148), predominantly white and female, …


In Vivo Evaluation Of Cromolyn Sodium Topical Gels For The Treatment Of Atopic Dermatitis, Adela Adu Agyemang Apr 2025

In Vivo Evaluation Of Cromolyn Sodium Topical Gels For The Treatment Of Atopic Dermatitis, Adela Adu Agyemang

Dr. Jay W. Boland Research Day

Cromolyn sodium (CS) is a mast cell stabilizer used for asthma and mastocytosis, with potential for treating atopic dermatitis (AD). Despite clinical support for its efficacy in AD, no commercial CS formulations are available. This study assessed the efficacy of a formulated CS gel for AD through in vivo testing in a mice model, comparing it to a topical corticosteroid. Two 4% CS gels were formulated using sodium oleate and sodium caprylate as enhancers. Hydroxypropyl cellulose (1.5%) was the gelling agent, and propylene glycol served as the base. In vitro permeation studies (24 h, porcine ear skin, 37°C) showed that …


Effects Of Ph On Products Yield Of One-Electron Oxidation To Guanine Derivatives, Abdul-Kadir Ibrahim Apr 2025

Effects Of Ph On Products Yield Of One-Electron Oxidation To Guanine Derivatives, Abdul-Kadir Ibrahim

Dr. Jay W. Boland Research Day

One-electron oxidation plays a major role in oxidative DNA damage in biological cells. Guanine, the most oxidizable DNA base, has been the major focus of studies on oxidative damage to DNA initiated by one-electron oxidation (OEO). Recently, the Roginskaya group has discovered a novel type of products of dGuo· dimerization, D1 and D2, formed as a result of oxidation reaction of 2´-deoxyguanosine (dGuo), initiated by OEO. A proposed reaction mechanism assumes recombination of the two dGuo· radicals and further hydrolysis of the resultant intermediates to form diastereomers of D1A and D1B along with their oxidized product D2. The oxidation of …


Exploring Transitions In Prenatal Maternal Tobacco Use: Evidence From The Prams Data, Chukwubuikem Arize Apr 2025

Exploring Transitions In Prenatal Maternal Tobacco Use: Evidence From The Prams Data, Chukwubuikem Arize

Dr. Jay W. Boland Research Day

Tobacco use remains a leading cause of preventable morbidity and mortality, with smoking during pregnancy posing significant risks to the mother, fetus, and child. Limited research exists on transitions in tobacco use during pregnancy. This study aims to identify factors associated with behavioral shifts, including transitions from exclusive cigarette smoking to dual use or from non-smoking to smoking or e-cigarette use. This study utilized national data from Phase 8 of the Pregnancy Risk Assessment Monitoring System (PRAMS) (2016–2021; N=216,035). Descriptive statistics and multivariable logistic regression analyses examined sociodemographic, health system, and geographic factors influencing transitions in tobacco use behaviors among …


Management Of A Patient In Septic Shock With Necrotizing Fasciitis And Diabetic Ketoacidosis, Avery Conkin Apr 2025

Management Of A Patient In Septic Shock With Necrotizing Fasciitis And Diabetic Ketoacidosis, Avery Conkin

Dr. Jay W. Boland Research Day

Each year over 1.7 million adults in the United States develop sepsis with 350,000 of those patients dying or being discharged to hospice. Sepsis is broken into four tiers: systemic inflammatory response syndrome, sepsis, severe sepsis, or septic shock. These tiers define the severity of the patient’s condition. This case report details a patient presenting to the emergency department in septic shock and discusses the management of his condition. A 58 year-old white male presented with altered mental status, bradycardia, hypotension, and leg wounds. On presentation, he appeared gravely ill and his last known well was 2 days prior. On …


Establishing A Mouse Model Of Post-Traumatic Epilepsy Using Video-Eeg-Ecg Monitoring, Raina Desai Apr 2025

Establishing A Mouse Model Of Post-Traumatic Epilepsy Using Video-Eeg-Ecg Monitoring, Raina Desai

Dr. Jay W. Boland Research Day

Traumatic brain injury (TBI) is a major cause of death and permanent disability. Patients with TBI are at an increased risk of developing post-traumatic epilepsy (PTE), and it has been estimated that PTE may account for up to 20% of symptomatic epilepsy cases in the general population. The process of epileptogenesis is defined as the mechanism by which a brain insult starts a cascade that culminates in the development of spontaneous seizures. Following TBI, the occurrence of seizures has been categorized as immediate (< 24 h), early (days), or latent (weeks). These immediate and early seizures are considered to reflect the severity of the injury itself, whereas the latent seizures are thought to result from maturation of epileptogenic pathology. The specific objective of this pilot study was to establish a protocol for video-EEG-ECG of mice following TBI to determine latent PTE development. Mice underwent surgery and EEG-ECG electrodes were placed immediately prior to TBI via controlled cortical impact. We initially chose 2 depth levels of injury (1mm and 1.5mm). We determined that 1.5 mm led to a high mortality rate, leading us to proceed with 1 mm. Currently, we have detected (and verified) seizures in two of four mice at 4 weeks post injury. An additional 8 mice have been EEG analyzed, with potential seizures detected via EEG in five out of eight (awaiting verification). We found that there was post-ictal Atrial-Ventricular block in one mouse. We also observed large fluctuations in heart rate during seizure free periods. Further analysis of ECG recordings is ongoing. Overall, our goal is to establish a 50-60% PTE development rate in our model for future applications. Our findings on ECG abnormalities mimic those observed in other models of epilepsy, suggesting that neuro-cardiac interactions in TBI warrant deeper investigation.


Forecasting Lung And Colon Cancer Mortality Trends In Jamaica And The U.S. Using Multivariate Time Series Analysis, Shanice Douglas Apr 2025

Forecasting Lung And Colon Cancer Mortality Trends In Jamaica And The U.S. Using Multivariate Time Series Analysis, Shanice Douglas

Dr. Jay W. Boland Research Day

Lung and colon cancers are among the leading causes of cancer-related mortality worldwide, with significant variations across different healthcare systems. This study applies multivariate time series modeling and forecasting to analyze lung and colon cancer mortality trends in Jamaica and the United States, examining each cancer type separately within each country and comparing trends between the two regions. The research employs Vector Autoregressive Moving Average (VARMA) models to assess the interdependence between lung and colon cancer mortality from 1960 to 2014 within Jamaica and the U.S. Multivariate forecasting will be performed separately for both countries to evaluate country-specific trends for …


Access To Rehabilitation Services For Cardiovascular Patients: Rural Vs. Urban Counties, Mercy Falade Apr 2025

Access To Rehabilitation Services For Cardiovascular Patients: Rural Vs. Urban Counties, Mercy Falade

Dr. Jay W. Boland Research Day

Cardiovascular disease remains the leading cause of death in the United States, with rehabilitation services playing a critical role in secondary prevention and patient recovery. However, disparities in access to these services persist between urban and rural areas. This study examines geographical differences in access to rehabilitation facilities using county-level data from the Area Health Resources File (AHRF). A cross-sectional analysis of 3,142 U.S. counties was conducted to compare facility distribution using two measures: (1) rehabilitation facilities per 100,000 residents and (2) the average number of facilities per county. Facility availability was assessed based solely on the number of rehabilitation …


Adoption Communicative Openness, Hannah Araba Baidoo Apr 2025

Adoption Communicative Openness, Hannah Araba Baidoo

Dr. Jay W. Boland Research Day

Adoption communicative openness refers to dialogue about adoption related issues between adoptive parents and their adopted child. It is through this form of communication that adoptive parents provide adoptees with information about their birth family, answer the adoptee’s questions, and explore other adoption related issues, and as a result aids in the psychological well-being of adoptees as they age. While it is important and beneficial for adoptees’ development, existing research has demonstrated the importance of adoption communicative openness (ACO) from the perspective of the parent in the interest of the adopted child without inquiring from the perspective of the adoptive …


The Biafran War (1967-1970) And Its Humanitarian Crisis, David Odey Apr 2025

The Biafran War (1967-1970) And Its Humanitarian Crisis, David Odey

Dr. Jay W. Boland Research Day

A devastating conflict ravaged the eastern region of Nigeria between 1967 and 1970, known as the Biafran War, resulting in catastrophic humanitarian crisis. This conflict, otherwise known as the Nigerian Civil War, was an attempt by the Eastern region to secede from the country and form an independent state called Biafra. An estimated two million civilians of Eastern Nigerian origin perished from the conflict. The survivors contended with severe malnutrition, widespread disease outbreaks, and forced displacement, exacerbating the humanitarian disaster. The war posed a significant challenge to the effectiveness and relevance of the United Nations Security Council in the maintenance …


Using The Reverse Testing Algorithm To Detect A Case Of Ocular Syphilis, Emily Rhoton Apr 2025

Using The Reverse Testing Algorithm To Detect A Case Of Ocular Syphilis, Emily Rhoton

Dr. Jay W. Boland Research Day

According to the Center for Disease Control and Prevention (CDC), incidence rates of syphilis have been steadily increasing in the United States over the last 5 years, despite well-established treatment and prevention precautions. Importantly, ocular syphilis can be the only presenting symptom in up to 40% of patients diagnosed with syphilis. This case report aims to identify symptoms, investigative factors, and ethical considerations involved in ocular syphilis to better recognize and manage future cases. An IRB-approved descriptive study and thorough chart review was conducted to examine the clinical presentation, diagnosis, and medical management course of a male in his mid-50s …


National Security Law, Barbara Linney, Orga Cadet, Geoffrey Goodale, Jonathan Meyer Apr 2025

National Security Law, Barbara Linney, Orga Cadet, Geoffrey Goodale, Jonathan Meyer

The Year in Review

No abstract provided.


International Trade, Theodore P. Brackemyre, Dharmendra N. Choudhary, Jake Frischknecht, Cynthia C. Galvez, Geoffrey M. Goodale, Jordan C. Kahn, Molly O'Casey, Vidushi Shrimali Apr 2025

International Trade, Theodore P. Brackemyre, Dharmendra N. Choudhary, Jake Frischknecht, Cynthia C. Galvez, Geoffrey M. Goodale, Jordan C. Kahn, Molly O'Casey, Vidushi Shrimali

The Year in Review

No abstract provided.


International Animal Law, Daina Bray, Paula Cardoso, Jessica Chapman, Hira Jaleel, Rajesh K. Reddy, Joan Schaffner Apr 2025

International Animal Law, Daina Bray, Paula Cardoso, Jessica Chapman, Hira Jaleel, Rajesh K. Reddy, Joan Schaffner

The Year in Review

No abstract provided.


Export Controls And Economic Sanctions, John Boscariol, Sylvia Costelloe, Abigail Cotterill, Mary Mikhaeel, Timothy O'Toole, Christopher Stagg, Lawrence Ward Apr 2025

Export Controls And Economic Sanctions, John Boscariol, Sylvia Costelloe, Abigail Cotterill, Mary Mikhaeel, Timothy O'Toole, Christopher Stagg, Lawrence Ward

The Year in Review

No abstract provided.


Customs Law, Adrienne Braumiller, Shannon Fura, David J. Glynn, Geoffrey Goodale, Lawrence Hanson, Jeremy Page, Michael Roll, George Tuttle Iii Apr 2025

Customs Law, Adrienne Braumiller, Shannon Fura, David J. Glynn, Geoffrey Goodale, Lawrence Hanson, Jeremy Page, Michael Roll, George Tuttle Iii

The Year in Review

No abstract provided.


International Section Ethics Committee, David Levine, Amy Bowers, Antonia Iragorri, Tiffany Comprés, Roland Potts Apr 2025

International Section Ethics Committee, David Levine, Amy Bowers, Antonia Iragorri, Tiffany Comprés, Roland Potts

The Year in Review

No abstract provided.


International Refugee Law, Banke Olagbegi-Oloba, Marie Isabelle Dumont, Marlyse Sime, Reuben Moses Apr 2025

International Refugee Law, Banke Olagbegi-Oloba, Marie Isabelle Dumont, Marlyse Sime, Reuben Moses

The Year in Review

No abstract provided.


International Human Rights, Daniel L. Appelman, Carlos De Miguel Perales, Corrine Lewis, Shauna Curphey, Lawrence C. Locker, Sara Sandford, Cyreka Jacobs, Jaclyn Fortini Laing, Morvarid Bagheri, Constance Z. Wagner Apr 2025

International Human Rights, Daniel L. Appelman, Carlos De Miguel Perales, Corrine Lewis, Shauna Curphey, Lawrence C. Locker, Sara Sandford, Cyreka Jacobs, Jaclyn Fortini Laing, Morvarid Bagheri, Constance Z. Wagner

The Year in Review

No abstract provided.


International Family Law, Robert G. Spector, Melissa A. Kucinski Apr 2025

International Family Law, Robert G. Spector, Melissa A. Kucinski

The Year in Review

No abstract provided.


International Employment Law, Poorvi Chothani, Ashwina Pinto Apr 2025

International Employment Law, Poorvi Chothani, Ashwina Pinto

The Year in Review

No abstract provided.


Immigration And Naturalization, Eshigo P. Okasili, Michael Freestone, Hon. Joan Churchill, Betina Schlossberg Apr 2025

Immigration And Naturalization, Eshigo P. Okasili, Michael Freestone, Hon. Joan Churchill, Betina Schlossberg

The Year in Review

No abstract provided.


Private International Law, Houston Putnam Lowry Apr 2025

Private International Law, Houston Putnam Lowry

The Year in Review

No abstract provided.


International Finance & Securities, Walter Stuber, Mohamed Hashish Apr 2025

International Finance & Securities, Walter Stuber, Mohamed Hashish

The Year in Review

No abstract provided.


Middle East, Kelly Blount, Harry Baumgarten, Nicolas Bremer, Benjamin Leventhal, Austin Pierce, Seyed Mohsen Rowhani, Howard L. Stovall, Michael Traison Apr 2025

Middle East, Kelly Blount, Harry Baumgarten, Nicolas Bremer, Benjamin Leventhal, Austin Pierce, Seyed Mohsen Rowhani, Howard L. Stovall, Michael Traison

The Year in Review

No abstract provided.


Europe, James Henry Bergeron, Willem Den Hertog, Jonathan A. Mcgowan, Valeria Camboni Miller, Austin Pierce, Matthew Soper Apr 2025

Europe, James Henry Bergeron, Willem Den Hertog, Jonathan A. Mcgowan, Valeria Camboni Miller, Austin Pierce, Matthew Soper

The Year in Review

No abstract provided.


Africa, Tereza Garcia André, Anne Bodley, Mankah Fombang, Sara Frazão, Laverne Lewis Gaskins, Tyler Holmes, Momodou Manneh, Mary Musoni, Flora Mweseli, Yaa Boatemaa Ohene-Bonsu, Ivan Ojakol, Ricardo Alves Silva, Tania Tossa Apr 2025

Africa, Tereza Garcia André, Anne Bodley, Mankah Fombang, Sara Frazão, Laverne Lewis Gaskins, Tyler Holmes, Momodou Manneh, Mary Musoni, Flora Mweseli, Yaa Boatemaa Ohene-Bonsu, Ivan Ojakol, Ricardo Alves Silva, Tania Tossa

The Year in Review

No abstract provided.


Women's Interest Network, Christine Korper Ed., Hannah Alderks, Marie Elena Angulo, Erica Burgos, Michela Cocchi, Estafanía Díaz González, Angela M. Gallerizzo, Dolly Hernandez, Margaret Kamm, Dana Katz, Julie King, Sierra Paola, Vanessa Romero Rocha, Aina Serret, Sandhya Taneja, Lisa Wolf Apr 2025

Women's Interest Network, Christine Korper Ed., Hannah Alderks, Marie Elena Angulo, Erica Burgos, Michela Cocchi, Estafanía Díaz González, Angela M. Gallerizzo, Dolly Hernandez, Margaret Kamm, Dana Katz, Julie King, Sierra Paola, Vanessa Romero Rocha, Aina Serret, Sandhya Taneja, Lisa Wolf

The Year in Review

No abstract provided.


Sexual Orientation And Gender Identity, Mark E. Wojcik Apr 2025

Sexual Orientation And Gender Identity, Mark E. Wojcik

The Year in Review

No abstract provided.