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Leveraging Natural Variation In Yeast To Understand Susceptibility Differences In Parkinson’S Disease, Julio Andres Molina Pineda May 2025

Leveraging Natural Variation In Yeast To Understand Susceptibility Differences In Parkinson’S Disease, Julio Andres Molina Pineda

Graduate Theses and Dissertations

Parkinson’s Disease (PD) is a neurodegenerative disorder that causes countless suffering around the world. Both forms, familial and sporadic, have been associated with the misfolding and cytotoxicity of α-synuclein, an otherwise non-pathogenic protein suspected to have various roles in the normal maintenance of the central nervous system. Model organisms have emerged as great vessels to uncover the cellular and molecular mechanisms that shape α-syn biology, and great strides have been made to understand it. Yet, it is still unclear why some individuals are affected by α-syn toxicity, while others not so much. Since it’s extremely complicated to study and probe …


The Role Of Arkansas Rural Libraries In Cultural Capital Development, Callie Spear Embry May 2025

The Role Of Arkansas Rural Libraries In Cultural Capital Development, Callie Spear Embry

Graduate Theses and Dissertations

This study explores the role of rural public libraries in Arkansas in fostering cultural capital development among youth. By employing a mixed-methods approach combining quantitative analysis from the 2022 Arkansas Public Library Survey and qualitative insights gathered from semi-structured interviews with rural librarians, the research investigates three core questions: (1) How do rural libraries impact youth cultural capital development? (2) In what ways can these libraries enhance their effectiveness in this area? (3) How do librarians perceive their roles in this developmental process?

Findings indicate that rural libraries serve as pivotal cultural coordinators and community hubs, positively affecting youth engagement …


Victims Of Stage And Screen: Parasocial Savior Rhetoric And Coded Social Critique At The Convergence Of Celebrity & Conspiracy Cultures, Amy Whiteside May 2025

Victims Of Stage And Screen: Parasocial Savior Rhetoric And Coded Social Critique At The Convergence Of Celebrity & Conspiracy Cultures, Amy Whiteside

Graduate Theses and Dissertations

This thesis offers a critical rhetorical analysis of what I term parasocial savior conspiracy theories , a unique genre of conspiracy narrative that portrays a public figure as victimized and allows their fans to step into a savior role through their advancement of the conspiracy theory. These narratives, I argue, are both catalyzed by and further insulative to a fan’s parasocial relationship with the public figure in question. Herein, the celebrity acts as a vessel of projection for their fans’ anxieties about control, allowing them to displace their agency panic onto a beloved external party and critique factors that seem …


Insights From Automated Mineralogic Analysis Of Modern Sand, Quinten Jones May 2025

Insights From Automated Mineralogic Analysis Of Modern Sand, Quinten Jones

Graduate Theses and Dissertations

Methods for determining and categorizing the modal compositions of sand and sandstone have long been a subject of debate in the field of sedimentary geology. Point counting is the most commonly used technique for determining modal compositions from petrographic slides, which are then categorized based on relative proportions of quartz, feldspar, and rock (or lithic) fragments. However, this approach fails to adequately preserve relevant textural data, such as grain size and sorting, which play an important role in diagenesis and in influencing reservoir quality. Additionally, the categorical nature of point counting results in a lack of specificity and loss of …


The Rhetorical Use Of The Lower Classes In Three Primary Accounts Of The First Crusade, John Hannon May 2025

The Rhetorical Use Of The Lower Classes In Three Primary Accounts Of The First Crusade, John Hannon

Graduate Theses and Dissertations

This study analyzes the rhetorical use of the lower classes in three primary accounts of the First Crusade: Albert of Aachen, the Gesta Francorum, and Raymond of Aguilers — specifically with an eye towards the proper maintenance of the order of society through everyone performing their assigned role. Through a close reading of these three texts this study demonstrates how the three authors engage with and uphold versions of the idealized three orders model of medieval society. Though there is nuance between each source, broadly, each of the authors presents the lower classes as a force that needs to …


The Evolving Changes In The Regionalization Of Export Bans On U.S. Poultry Trade From The 2015 And 2022 Highly Pathogenic Avian Influenza Events, Kylie A. Roesler May 2025

The Evolving Changes In The Regionalization Of Export Bans On U.S. Poultry Trade From The 2015 And 2022 Highly Pathogenic Avian Influenza Events, Kylie A. Roesler

Graduate Theses and Dissertations

As food security becomes a growing concern worldwide in a trading system dominated by globalization, the safeguarding of a bio-secure food system is at risk. One of the greatest risks to this stability of the system is, highly pathogenic avian influenza or HPAI which is growing in frequency and impact. Therefore, the global response to disease events is evolving into a newfound understanding of disease prevalence across the animal protein industries. This study will analyze the 2022 HPAI event in the United States regarding the regionalization of restrictions imposed by trading partners accounting for trade agreements executed. The examination of …


The Future Of Fashion: A Systematic Literature Review On Consumer Willingness To Pay For Green Apparel, Emma Clark May 2025

The Future Of Fashion: A Systematic Literature Review On Consumer Willingness To Pay For Green Apparel, Emma Clark

Graduate Theses and Dissertations

In recent years, consumers have become highly aware of the environmental impact of their purchases, specifically of apparel products. Accordingly, apparel brands have increasingly focused on enhancing the sustainability of their product offerings to attract environmentally conscious consumers and elevate their brand image (Dangelico et al., 2022). Furthermore, most sustainably produced products are priced higher for consumers compared to standard alternatives (Elmanadily & El-Deeb, 2022). Research has shown that consumers can accept higher prices for products that do less harm to the environment (Gomes et al., 2023), but it has yet to be determined in which cases this is consistently …


Evolutionarily Conserved Functions Of The Gene Frazzled In Midline Axon Guidance In Drosophila Melanogaster And Tribolium Castaneum., Piyasi Ghosh May 2025

Evolutionarily Conserved Functions Of The Gene Frazzled In Midline Axon Guidance In Drosophila Melanogaster And Tribolium Castaneum., Piyasi Ghosh

Graduate Theses and Dissertations

Axon guidance in bilaterians is often controlled by various signaling pathways in the nervous system, which determine the fate of the axons if they cross the midline or not. One such pathway involved is the ligand-receptor pair Netrin (Net) and Frazzled (Fra), which is also known as the attractive pathway that promotes midline crossing axons in insects and other bilaterians. Orthologs of the pathway ligand Netrins and their receptors Frazzled [Fra] in insects and Deleted in Colorectal cancer [DCC] in vertebrates are widely conserved in bilaterians. How well these regulatory roles of the protein are conserved is poorly understood. In …


Sibling Groups And Family Adaptability And Cohesion Among Emerging Adult Women, Julianne M. Post May 2025

Sibling Groups And Family Adaptability And Cohesion Among Emerging Adult Women, Julianne M. Post

Graduate Theses and Dissertations

This study examined how sibling group size is related to family adaptability, cohesion, and individual resiliency outcomes during emerging adulthood. Using Bowen's Family Systems Theory and Olson's Circumplex Model, the research investigates sibling subsystems as sites where systemic imbalances are first experienced within families. Data from 124 college students revealed that larger sibling groups were associated with marginally higher disengagement and chaos resulting in decreased perceived social support, suggesting resiliency implications for youth growing up within larger families. While sibling size didn't directly predict mental health, family dynamics significantly mediated the relationship between sibling composition and resiliency outcomes. Demographic factors …


Koszul Cohomology Of Canonical Products, Alexander Scott Duncan May 2025

Koszul Cohomology Of Canonical Products, Alexander Scott Duncan

Graduate Theses and Dissertations

In this thesis, we give a complete classification of the Koszul cohomology groups Kp,1(C, B, ωC ⊗ B) on a smooth curve C of genus g ≥ 2 with B p-very ample. Such a classification in the case B = ωC has been incomplete until [5]. The classification follows easily from our main result which precisely calculates Kp,1(C, B, B ωC ⊗ B) in terms of h0(C, B). This result also handles the case B = ωC. A straightforward …


Bacterial Chondronecrosis With Osteomyelitis In Broiler Chickens: Experimental Lameness And Additive Probiotic Treatments, Amanda Anthney May 2025

Bacterial Chondronecrosis With Osteomyelitis In Broiler Chickens: Experimental Lameness And Additive Probiotic Treatments, Amanda Anthney

Graduate Theses and Dissertations

With the global population already surpassing 8.2 billion and expected to reach 9.7 billion by 2050, the poultry industry has seen a surge in demand due to its unmatched efficiency and affordability for consumers across the globe. Selective breeding and quality nutrition developments since the industry's commercialization have allowed producers to grow broilers up to 7 pounds by market age. While this extraordinarily efficient process has allowed quality poultry products to be available worldwide, the modern-day broiler has developed a multitude of musculoskeletal issues. Due to the lack of integral skeletal development to match the rapid production of muscle tissue, …


Literary Postcritique And American Transcendentalism: Helping Students Practice Community-Building By Rewilding Literature In The Classroom, Tate Aldrich May 2025

Literary Postcritique And American Transcendentalism: Helping Students Practice Community-Building By Rewilding Literature In The Classroom, Tate Aldrich

Graduate Theses and Dissertations

Literary postcritique is an emergent theoretical approach to literature that has elicited skepticism among many in academia because of its central claim that their unchecked overreliance on suspicious and symptomatic reading styles is diminishing the pedagogical potential of our reading together. To restore this potential, Rita Felski, a champion of literary postcritique, suggests adopting an aesthetic reading style, a mid-level interpretation that neither indulges in the formalists’ habits of close scrutiny nor in the cultural critics’ wider lens of political and social contexts. In The Limits of Critique and Hooked, Felski argues that an aesthetic reading style can develop …


Application Of Ordinal Regression Models To Acquired Stress Resistance In Wild Strains Of Saccharomyces Cerevisiae, Carson Stacy May 2025

Application Of Ordinal Regression Models To Acquired Stress Resistance In Wild Strains Of Saccharomyces Cerevisiae, Carson Stacy

Graduate Theses and Dissertations

This thesis explores the application of ordinal regression to the analysis of semi-quantitative growth assays often used when comparing fitness for different strains of the model yeast Saccharomyces cerevisiae. For stress survival assays, yeast stress resistance is measured using an ordered survival score that ranges from 0 (no growth) to 4 (confluent growth). Traditional approaches to analyze this type of data either treats data as a nominal categorical variable or as a continuous numerical variable. These approaches risk loss of information or violation of testing assumptions. In contrast, cumulative logit ordinal regression uses the information contained in the order …


Physiological And Molecular Responses Of Diverse Rice Genotypes Under Drought Stress, Huda Mohmmed Alshaya May 2025

Physiological And Molecular Responses Of Diverse Rice Genotypes Under Drought Stress, Huda Mohmmed Alshaya

Graduate Theses and Dissertations

Climate change-induced drought stress is a significant constraint on global rice (Oryza sativa L.) production, threatening food security. This study evaluated the drought resilience of 15 diverse rice genotypes from the USDA mini-core collection under field, greenhouse, and osmotic stress conditions. Field trials assessed reproductive-stage drought tolerance based on panicle length (PL), number of spikelets per panicle (NSP), and spikelet sterility (SS). Greenhouse experiments examined moisture retention at the vegetative stage. Significant genotypic variation was observed, with genotypes 310724, 310779, 311181, 311603, 311793, and Vandana exhibiting drought tolerance through stable PL and SS. Additionally, genotypes 310100, 310428, 311255, N22, …


The Relationship Between Attention Deficit Hyperactivity Disorder And Problematic Internet Usage In Lgbtq+ Adults, Kayli Nicole Heigelmann May 2025

The Relationship Between Attention Deficit Hyperactivity Disorder And Problematic Internet Usage In Lgbtq+ Adults, Kayli Nicole Heigelmann

Graduate Theses and Dissertations

This thesis explores how LGBTQ+ adults who experience attention deficit hyperactivity disorder (ADHD) symptomology perceive and navigate potential problematic Internet usage (PIU). Utilizing a qualitative, phenomenological approach, twelve participants were interviewed to gain insight on how neurodivergence, queer identity, and Internet engagement intersect. Findings revealed two overarching themes: 1) the interplay between PIU, ADHD, and sexual/gender diversity, and 2) the meaning of the Internet for individuals with intersecting minority identities. Participants widely endorsed the Internet as an important space for identity negotiation, community, and affirmation for their multiple minority statuses, but acknowledged their vulnerability to the Internet’s attention-capturing mechanisms, reporting …


In Vitro And In Vivo Evaluation Of The Effect Of A Commercial-Dried Enterococcus Faecium Fermentation Product As Quorum Sensing Inhibitors Of Salmonella Enterica Typhimurium, Ileana Loeza May 2025

In Vitro And In Vivo Evaluation Of The Effect Of A Commercial-Dried Enterococcus Faecium Fermentation Product As Quorum Sensing Inhibitors Of Salmonella Enterica Typhimurium, Ileana Loeza

Graduate Theses and Dissertations

The purpose of the present research was to evaluate Enterococcus faecium fermentation peptides (EFP) for antibacterial activity, inhibition of biofilm formation, and anti-quorum sensing properties against Salmonella Typhimurium (ST) in in vitro trials and individual body weight and ST organ colonization in therapeutic and prophylactic models in broiler chickens. Ninety-six day-of-hatch Cobb 500 broiler chickens were randomized and assigned to one of four treatments: NC) Negative Control, no EFP treatment and no ST challenge; NC+EFP) Negative Control, EFP treatment and no ST; PC) Positive Control, no EFP treatment and ST challenge, and PC+EFP) EFP treated and ST challenged. Independent trials …


Fergus Of Galloway: A New Translation For A New Audience, Emily J. Aguayo May 2025

Fergus Of Galloway: A New Translation For A New Audience, Emily J. Aguayo

Graduate Theses and Dissertations

My dissertation focuses on one text – Li romanz de Fergus – an Arthurian romance composed in Old French in the early thirteenth century by a mysterious author named Guillaume le Clerc. I have learned as much as I can about this romance and have looked at it from every angle possible. The scope of my research is narrow and deep because it focuses on one text, its author, and its subject matter. I have created a new theory about the identity of the author, Guillaume le Clerc, based on historical documents such as the Acts of Lordship from Scotland, …


Door - To - Door Summer Sales And Other Summer Employment: A Cost And Benefit Analysis, Jentrie Gilliland May 2025

Door - To - Door Summer Sales And Other Summer Employment: A Cost And Benefit Analysis, Jentrie Gilliland

Undergraduate Honors Capstone Projects

Door-to-door summer sales is heavily marketed to college students, especially on university campuses in Utah. These employment options are marketed as having high financial rewards while giving students the opportunity to develop their professional skills. In this study, I examine whether these expected rewards are delivered and if door-to-door summer sales is a viable position for college students in comparison to other summer employment. Specifically, I focus on the financial benefits and skills gained from both job types as well as determinants for students who participate in door-to-door summer sales versus other summer employment. My findings indicate that there is …


Evaluating Bone Fracture Healing In A Rabbit Model Using Doppler Imaging Modes, Shear Wave Elastography, X-Ray, And Dual-Energy X-Ray Absorptiometry, Priscilla Machado, Rachel Blackman, Ji-Bin Liu, Collleen Dempsey, Flemming Forsberg, Traci Fox May 2025

Evaluating Bone Fracture Healing In A Rabbit Model Using Doppler Imaging Modes, Shear Wave Elastography, X-Ray, And Dual-Energy X-Ray Absorptiometry, Priscilla Machado, Rachel Blackman, Ji-Bin Liu, Collleen Dempsey, Flemming Forsberg, Traci Fox

Department of Radiology Faculty Papers

OBJECTIVE: This study investigated methods of evaluating the bone fracture healing process using superb microvascular imaging (SMI; two modes color SMI [cSMI] and monochromeSMI [mSMI]), and shear wave elastography (SWE), relative to X-ray, dual-energy X-ray absorptiometry (DXA), and platelet endothelial cell adhesion molecule 1 (PECAM-1) also know as cluster of differentiation 31 (CD-31) staining in a rabbit model.

METHODS: This IACUC-approved study involved eight rabbits that underwent a bilateral fibula osteotomy and were followed for 7 or 21 days (Groups 1 and 2 with 4 rabbits in each). Ultrasound examinations using cSMI, mSMI, and SWE were performed on Days 0, …


Accreditation Update, Georgia Southern University May 2025

Accreditation Update, Georgia Southern University

Institutional Assessment & Accreditation

  • Celebrating a Successful Reaffirmation Visit
  • STATUS UPDATE: We are in Phase 6
  • Section 14: Transparency & Institutional Representation


Limit Theory For Local Polynomial Estimation Of Functional Coefficient Models With Possibly Integrated Regressors, Ying Wang, Peter C. B. Phillips May 2025

Limit Theory For Local Polynomial Estimation Of Functional Coefficient Models With Possibly Integrated Regressors, Ying Wang, Peter C. B. Phillips

Research Collection School Of Economics

Limit theory for functional coefficient cointegrating regression was recently found to be considerably more complex than earlier understood. The issues were explained and correct limit theory derived for the kernel weighted local level estimator in Phillips and Wang (2023b). The present paper provides complete limit theory for the general kernel weighted local th order polynomial estimators of the functional coefficient and the coefficient derivatives. Both stationary and nonstationary regressors are allowed. Implications for bandwidth selection are discussed. An adaptive procedure to select the fit order  is proposed and found to work well. A robust -ratio is constructed following the new …


The Backdrop Of Leadership: How Environmental Awe Influences Charisma Attributions, Jack Mcguire, Nicolas Bastardoz, Leonie J. Hentrup, David De Cremer, Jochen I. Menges May 2025

The Backdrop Of Leadership: How Environmental Awe Influences Charisma Attributions, Jack Mcguire, Nicolas Bastardoz, Leonie J. Hentrup, David De Cremer, Jochen I. Menges

Research Collection Lee Kong Chian School Of Business

Charisma is often attributed to leaders based on how they look, talk, and behave. Yet very little is known about the role of the physical environment in influencing attributions of leader charisma. The role of the physical environment is crucial because leaders inevitably occupy physical spaces that vary across contexts. In this research, we find that the grandeur of the physical environment, specifically in its ability to induce awe, enhances attributions of charisma for leaders who are not already known to be charismatic. First, in a field experiment, we show that a real business leader is attributed with more charisma …


Voting For Winners And Losers In A Hybrid Regime: How Thailand's 2023 Election Shaped Voter Opinion, Jacob Ricks, Allen Hicken May 2025

Voting For Winners And Losers In A Hybrid Regime: How Thailand's 2023 Election Shaped Voter Opinion, Jacob Ricks, Allen Hicken

Research Collection School of Social Sciences

Research in Western Democracies suggests voting has substantive impacts on how one feels about democracy and state institutions. Voting for winners leads to positive feelings while voting for losers has the opposite effect. How, though, do voters interpret electoral results in a system prone to authoritarian intervention? Thailand's 2023 election offers a unique opportunity to examine how voting in a hybrid regime can impact voter opinion. Using a pre- and postelection survey, we demonstrate that, like elections in democracies, an election in a hybrid regime can have a significant impact on voter opinions. When pro-democracy voters win an election in …


Oscar: Object Status And Contextual Awareness For Recipes To Support Non-Visual Cooking, Franklin Mingzhe Li, Kaitlyn Ng, Bin Zhu, Patrick Carrington May 2025

Oscar: Object Status And Contextual Awareness For Recipes To Support Non-Visual Cooking, Franklin Mingzhe Li, Kaitlyn Ng, Bin Zhu, Patrick Carrington

Research Collection School Of Computing and Information Systems

Following recipes while cooking is an important but difficult task for visually impaired individuals. We developed OSCAR (Object Status Context Awareness for Recipes), a novel approach that provides recipe progress tracking and context-aware feedback on the completion of cooking tasks through tracking object statuses. OSCAR leverages both Large-Language Models (LLMs) and Vision-Language Models (VLMs) to manipulate recipe steps, extract object status information, align visual frames with object status, and provide cooking progress tracking log. We evaluated OSCAR’s recipe following functionality using 173 YouTube cooking videos and 12 real-world non-visual cooking videos to demonstrate OSCAR’s capability to track cooking steps and …


Seaexam And Seabench: Benchmarking Llms With Local Multilingual Questions In Southeast Asia, Chaoqun Liu, Wenxuan Zhang, Jiahao Ying, Mahani Aljunied, Anh Tuan Luu, Lidong Bing May 2025

Seaexam And Seabench: Benchmarking Llms With Local Multilingual Questions In Southeast Asia, Chaoqun Liu, Wenxuan Zhang, Jiahao Ying, Mahani Aljunied, Anh Tuan Luu, Lidong Bing

Research Collection School Of Computing and Information Systems

This study introduces two novel benchmarks, SeaExam and SeaBench, designed to evalu ate the capabilities of Large Language Models (LLMs) in Southeast Asian (SEA) application scenarios. Unlike existing multilingual datasets primarily derived from English translations, these benchmarks are constructed based on real world scenarios from SEA regions. SeaExam draws from regional educational exams to form a comprehensive dataset that encompasses sub jects such as local history and literature. In contrast, SeaBench is crafted around multi turn, open-ended tasks that reflect daily inter actions within SEA communities. Our evalua tions demonstrate that SeaExam and SeaBench more effectively discern LLM performance on …


Rationality Analysis Of Antibiotics For Community-Acquired Pneumonia In Adult Inpatients At X Hospital Sukoharjo, Rolando Rahardjoputro, Adhi W. Amrullah, Wahyu Rizky, Ernawati Ernawati, Andrey Wahyudi, Nova R. Widyaningrum May 2025

Rationality Analysis Of Antibiotics For Community-Acquired Pneumonia In Adult Inpatients At X Hospital Sukoharjo, Rolando Rahardjoputro, Adhi W. Amrullah, Wahyu Rizky, Ernawati Ernawati, Andrey Wahyudi, Nova R. Widyaningrum

Pharmacology and Clinical Pharmacy Research

Community-acquired pneumonia in adult patients contributes to high morbidity and mortality rates. The rationality of antibiotics for community-acquired pneumonia pharmacotherapy can determine the result of patient clinical outcomes. The aim of this study was to determine antibiotics rationality for community-acquired pneumonia in adult inpatients at X Hospital Sukoharjo and relationship between antibiotics rationality and its clinical outcomes.This study was analytical cohort design with retrospective data in the form of patient medical records for the period 2022. Sampling method was carried out using total sampling with inclusion criteria being patients aged ≥ 18 years, male or female, diagnosed with community-acquired pneumonia …


Factors Associated With Men’S Skincare Sales At Shopee Indonesia E-Commerce, Muhamad H. Effendi, Lalu E.H Mulyono May 2025

Factors Associated With Men’S Skincare Sales At Shopee Indonesia E-Commerce, Muhamad H. Effendi, Lalu E.H Mulyono

Pharmacology and Clinical Pharmacy Research

Men's skincare use is increasing, along with the awareness of its importance. Shopee, as one of the largest e-commerce platforms in Indonesia, has become the main place for purchasing men's skincare products. However, study on the factors influencing men's skincare sales at e-commerce is still limited. This research aims to identify the factors associated with men's skincare sales at Shopee Indonesia e-commerce. A cross-sectional study, utilizing data from the 100 best-selling men's skincare products on Shopee until September 2024, was conducted. The dependent variable is the number of men's skincare sales, and the independent variables are the number of reviews, …


Robust Statistical Techniques For Operational Maintenance Of The 10.7 Cm Solar Radio Flux, Daniel A. Brandt, Erick F. Vega, Brian Thelen May 2025

Robust Statistical Techniques For Operational Maintenance Of The 10.7 Cm Solar Radio Flux, Daniel A. Brandt, Erick F. Vega, Brian Thelen

Michigan Tech Publications

The F10.7 solar radio flux is a critical quantity for operational space weather nowcasting and forecasting, where it is routinely used as a driver for coupled atmospheric models to estimate a variety of important quantities such as the neutral atmospheric density. Although there have been several successful developments in the way of parametric modeling to ensure F10.7 coverage during outages (often using the sunspot number or radio flux observations at neighboring wavelengths), these developments have refrained from employing comprehensive cross-validation schemes to ensure model generalizability, and can benefit from recently-developed techniques for modeling nonlinear phenomena. We present an approach that …


Symbiotic International Law: Combatting Uyghur Forced Labor, Preston Jordan Lim May 2025

Symbiotic International Law: Combatting Uyghur Forced Labor, Preston Jordan Lim

Utah Law Review

Since 2017, the Chinese government has launched a campaign of repression against the Muslim Turkic minorities of Xinjiang, a region located in China’s Northwest. While most scholars have focused on the mass internment of Uyghurs and other minorities, this Article highlights an under-discussed aspect of China’s campaign: the construction of a sophisticated forced labor system. Minority forced labor supplies key sectors of the global economy—from the automotive to the energy sectors—and allows Chinese companies to outcompete foreign firms. The unprecedented scope and sophistication of what I term the “modern Xinjiang forced labor system” imperils the very future of the international …


Planning For Scale: Analysis Of Adaptations And Contextual Factors Influencing Scale-Up Of The Quali-Dec Intervention To Optimize Caesarean Section Use, Soha El-Halabi, Claudia Hanson, Alexandre Dumont, Amanda Cleeve, Helle Mölsted Alvesson, Charles Kaboré, Guillermo Carroli, Pisake Lumbiganon, Quoc Nhu Hung Mac, Ana Pilar Betran May 2025

Planning For Scale: Analysis Of Adaptations And Contextual Factors Influencing Scale-Up Of The Quali-Dec Intervention To Optimize Caesarean Section Use, Soha El-Halabi, Claudia Hanson, Alexandre Dumont, Amanda Cleeve, Helle Mölsted Alvesson, Charles Kaboré, Guillermo Carroli, Pisake Lumbiganon, Quoc Nhu Hung Mac, Ana Pilar Betran

Centre of Excellence in Women and Child Health

Background: Researchers are encouraged to plan for scale through purposeful and guided assessment of scalability of an intervention. This study analysed factors potentially influencing scale-up and synthesised early adaptations of the QUALI-DEC intervention aiming to improve the appropriate use of caesarean section. The intervention consists of opinion leader engagement, audit and feedback for caesarean section, a tool to help women make an informed decision on the mode of birth, and labour companionship.

Methods: We conducted a framework analysis, which was guided by the scalability assessment framework by Zamboni et al., a 34-item checklist with a three-point scale. We used data …