Digital Commons Network^™

Genome Wide Association Study Of Fusarium Wilt Resistance In Spinacia Turkestanica, Sanjaya Gyawali, Gehendra Bhattarai, James C. Correll, Ainong Shi, Lindsey J. Du Troit

Horticulture Faculty Publications and Presentations

Fusarium wilt of spinach, caused by Fusarium oxysporum f. sp. spinaciae (Fos), leads to substantial losses in spinach (Spinacia oleracea) seed production in the only region of the USA suitable for growing spinach seed crops, the maritime Pacific Northwest. Accessions of wild spinach, S. turkestanica, serve as a major source of resistance to multiple spinach diseases. In this study, 84 Spinacia genotypes (all 68 S. turkestanica accessions available publicly and 16 S. oleracea) were evaluated for reactions to Fos at medium and high densities of inoculum comprising a mix of isolates of races 1 and 2, using a factorial experimental …

Expedition 399 Methods, S. Q. Lang, A. M. Mccaig, P. Blum, N. Abe, W. Brazelton, R. Coltat, J. R. Deans, K. L. Dickerson, M. Godard, B. E. John, F. Klein, R. Kuehn, K. Y. Lin, C. J. Lissenberg, H. Liu, E. L. Lopes, T. Nozaka, A. J. Parsons, V. Pathak, M. K. Reagan, J. A. Robare, I. P. Savov, E. Schwarzenbach, O. J. Sissmann, G. Southam, F. Wang, C. G. Wheat

School of Geography, Earth and Environmental Sciences

No abstract provided.

Expedition 399 Summary, A. M. Mccaig, S. Q. Lang, P. Blum, N. Abe, W. Brazelton, R. Coltat, J. R. Deans, K. L. Dickerson, M. Godard, B. E. John, F. Klein, R. Kuehn, K. Y. Lin, C. J. Lissenberg, H. Liu, E. L. Lopes, T. Nozaka, A. J. Parsons, V. Pathak, M. K. Reagan, J. A. Robare, I. P. Savov, E. Schwarzenbach, O. J. Sissmann, G. Southam, F. Wang, C. G. Wheat

School of Geography, Earth and Environmental Sciences

International Ocean Discovery Program (IODP) Expedition 399 collected new cores from the Atlantis Massif (30°N; Mid-Atlantic Ridge), an oceanic core complex that hosts the Lost City hydrothermal field (LCHF). Studies of the Atlantis Massif and the LCHF have transformed our understanding of tectonic, magmatic, hydrothermal, and microbial processes at slow-spreading ridges. The Atlantis Massif was the site of four previous expeditions (Integrated Ocean Drilling Program Expeditions 304, 305, and 340T and IODP Expedition 357) and numerous dredging and submersible expeditions. The deepest IODP hole in young (<2 My) oceanic lithosphere, Hole U1309D, was drilled ~5 km north of the LCHF and reached 1415 meters below seafloor (mbsf) through a series of primitive gabbroic rocks. A series of 17 shallow (<16.4 mbsf) holes were also drilled at 9 sites across the south wall of the massif during Expedition 357, recovering heterogeneous rock types including hydrothermally altered peridotites, gabbroic, and basaltic rocks. The hydrologic regime differs between the two locations, with a low-permeability conductive regime in Hole U1309D and a high- (and possibly deep-reaching) permeability regime along the southern wall.

Site U1601, S. Q. Lang, A. M. Mccaig, P. Blum, N. Abe, W. Brazelton, R. Coltat, J. R. Deans, K. L. Dickerson, M. Godard, B. E. John, F. Klein, R. Kuehn, K. Y. Lin, C. J. Lissenberg, H. Liu, E. L. Lopes, T. Nozaka, A. J. Parsons, V. Pathak, M. K. Reagan, J. A. Robare, I. P. Savov, E. Schwarzenbach, O. J. Sissmann, G. Southam, F. Wang, C. G. Wheat

School of Geography, Earth and Environmental Sciences

No abstract provided.

Additive Manufacturing And Sustainability, Eric J. Venzor-Villarreal

Sustainable Supply Chain Management

This chapter explores the transformative role of Additive Manufacturing (AM), or 3D printing, within modern supply chains, with a particular focus on its adoption in the aerospace and defense industries. It begins by introducing the core technologies behind AM and tracing its historical development. The chapter then examines the advantages of AM—such as reduced material waste, faster prototyping, and decentralized production. A detailed case study on Lockheed Martin showcases real-world applications. Comparative insights from other defense manufacturers and global leaders provide a broader context, reinforcing AM’s potential as a key driver of supply chain innovation and resilience.

The Built Environment And Adverse Cardiovascular Events In Us Veterans With Cardiovascular Disease, Skanda Moorthy, Zhuo Chen, Tong Zhang, Sai Rahul Ponnana, Santosh Kumar Sirasapalli, Kanimozhi Shivanantham, Haitham Khraishah, Jean Eudes Dazard, Sadeer G. Al-Kindi, Salil V. Deo, Sanjay Rajagopalan

Faculty Scholarship

Question: Can AI-extracted interpretable built environment features predict major adverse cardiovascular events (MACE) in a national veteran population? Findings: In this cohort study of 770,990 U.S. veterans, seven built environment features were significantly associated with an increased risk of MACE. Two features, old/dilapidated buildings and visible wire, were associated with a decreased risk. Greenery was only linked to increased risk in higher social deprivation index quartiles. Meaning: Built environment features can serve as predictors of MACE, highlighting the potential role of neighborhood characteristics in cardiovascular risk stratification beyond traditional factors. Importance: The relationship between built environment features and major adverse …

Role Of Fluid-Structure Interactions In Mechanosensation During Hovering Flapping Flight, Menglong Lei, Chengyu Li

Faculty Scholarship

Insect wings, known for their intricate structure and function, inherently deform during flapping motion. These deformations can be classified into chordwise cambering, spanwise bending, and root-to-tip twisting, arising from non-uniform venation distribution, aerodynamic loading, and wing inertia. Crucially, such deformations play a vital role in enhancing both aerodynamic performance and mechanosensory function. To investigate the complex interplay between wing structure, unsteady aerodynamics, and mechanosensation, we developed a fully coupled three-dimensional fluid-structure interaction (FSI) solver. This framework integrates an in-house Navier-Stokes equations solver for resolving the flow field with the open-source Vega FEM code to solve the solid structure dynamics. Our …

Daps In Action: The Role Of Science-Literacy Integration In Pre-Service Teacher Education, Brittany E. Kiser, Kelly A. Burlison

Faculty and Staff Publications & Presentations

This session proposes to establish the importance of incorporating developmentally appropriate science education into the literacy curriculum of pre-service early childhood teachers as well as to share experiences, work and insights of those pre-service teachers. As teacher educators, it is essential that we not only prepare our students to be impactful in the PK-3 classroom, but also that we mold them to be cognizant of developmentally appropriate practices in the early learning environment, despite unwieldy mandates. Not only will our pre-service teachers be educating PK-3 students with exponentially increasing technological skills; educational research also suggests the importance in blending curricula …

Alzheimer’S Disease Protective Allele Of Clusterin Modulates Neuronal Excitability Through Lipid-Droplet-Mediated Neuron-Glia Communication, Xiaojie Zhao, Yan Li, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Alena Kozlova, Matthew J Moulton, Lindsey D Goodman, Zhiping P Pang, Alan R Sanders, Hugo J Bellen, Gopal Thinakaran, Jubao Duan

Duncan NRI Faculty and Staff Publications

Background: Genome-wide association studies (GWAS) of Alzheimer's disease (AD) have identified a plethora of risk loci. However, the disease variants/genes and the underlying mechanisms have not been extensively studied.

Methods: Bulk ATAC-seq was performed in induced pluripotent stem cells (iPSCs) differentiated various brain cell types to identify allele-specific open chromatin (ASoC) SNPs. CRISPR-Cas9 editing generated isogenic pairs, which were then differentiated into glutamatergic neurons (iGlut). Transcriptomic analysis and functional studies of iGlut co-cultured with mouse astrocytes assessed neuronal excitability and lipid droplet formation.

Results: We identified a putative causal SNP of CLU that impacted neuronal chromatin accessibility to transcription-factor(s), with …

Antibiotic De-Escalation In The Intensive Care Unit: Rationale And Potential Strategies, Sarah Singer Matuszak, Lauren Kolodziej, Scott Micek, Marin Kollef

2020-Current year OA Pubs

Antibiotic de-escalation (ADE) is important to help optimize antibiotic use and balance the positive and negative effects of antimicrobial therapy. ADE should be performed promptly, and infections should be treated with the shortest course of antimicrobials as clinically feasible to avoid unnecessary use of broad-spectrum antimicrobials. Several tools have been developed to increase efficient ADE, including rapid diagnostic tests (ex. multiplex PCR), MRSA nasal PCR/culture, and biomarkers. Multiplex PCR and MRSA nasal PCR/culture have been associated with reductions in inappropriate antibiotic use. Procalcitonin, a biomarker, has been associated with shorter antimicrobial durations in some studies; however, widespread use may be …

Healthcare Leadership In Western Societies: Religion, Politics, And Rhetoric, Nelly D. Figueroa-Herrera

Pepperdine Journal of Communication Research

No abstract provided.

Aung San Suu Kyi & The Speech At Shwedagon Pagoda, Ella Michael

Pepperdine Journal of Communication Research

No abstract provided.

The Rhetoric Of Pope Francis: Leadership Profile, Elizabeth Kresse

Pepperdine Journal of Communication Research

No abstract provided.

The Theotokos: A Model Of Unwavering Ethical Commitment, Emmeline F. Ross

Pepperdine Journal of Communication Research

No abstract provided.

Child Brokering: A Literature Review And Discussion, Nelly D. Figueroa-Herrera

Pepperdine Journal of Communication Research

No abstract provided.

Gender Inequality And Export Diversification In Afghanistan: A Critical Literature Review, Kolea Suehiro

Pepperdine Journal of Communication Research

No abstract provided.

How A Luxury Clothing Brand’S Country Of Origin Impacts Consumer Desirability And Status Perception: A Literature Review, Julia Wysocki

Pepperdine Journal of Communication Research

No abstract provided.

How Does Language In Emails Impact How Recipients Respond?, Ellya Asatryan

Pepperdine Journal of Communication Research

No abstract provided.

A Study On The Communication Of Religion In A Christian-University Context, Jessica Furrow

Pepperdine Journal of Communication Research

No abstract provided.

Ai-Generated Versus Human-Generated: Creative Content In Advertising, Elizabeth Burrow

Pepperdine Journal of Communication Research

No abstract provided.

The 'Other' In European Colonial Rhetoric: Race, Modernity, And The Legacy Of Imperialism", Mateo E. Roldan

Pepperdine Journal of Communication Research

No abstract provided.

The Priming Effect Of Music On Political Alignment, Katherine Hailey, Blue Brasher, Brandon Kim

Pepperdine Journal of Communication Research

No abstract provided.

Editor's Note, Elizabeth Kresse

Pepperdine Journal of Communication Research

No abstract provided.

Pepperdine Journal Of Communication Research Volume 15, Issues 1-3, Elizabeth Kresse

Pepperdine Journal of Communication Research

No abstract provided.

Why Fair Elections Get Fouled In Lesotho: A Search For Solutions, Richard F. Weisfelder

Journal of African Policy Studies

No abstract provided.

Mass Media, Civil Society And Democratization Of Politics In Botswana, James J. Zaffiro

Journal of African Policy Studies

No abstract provided.

Elections As A Cornerstone Of Democracy The Namibian Experience, Heribert Weiland

Journal of African Policy Studies

No abstract provided.

Electoral Manipulation In A Neo-Authoritarian Regime: The Case Of Zimbabwe, Daniel Compagnon

Journal of African Policy Studies

No abstract provided.

Democratic Consolidation And The ‘Normalization’ Of Politics Political Parties In South Africa’S 1999 Elections, David Pottie

Journal of African Policy Studies

No abstract provided.

Democracy Without A Credible Opposition: The Case Of Botswana, Staffon Darnolf, John D. Holm

Journal of African Policy Studies

No abstract provided.