Digital Commons Network^™

The Structure Of The Drp1 Lattice On Membrane, Kristy Rochon, Anelise N. Hutson, Jason A. Mears

Faculty Scholarship

Mitochondrial health relies on the membrane fission mediated by dynamin-related protein 1 (Drp1). Previous structural studies of Drp1 on remodeled membranes were hampered by heterogeneity, leaving a critical gap in the understanding of the mitochondrial fission mechanisms. Here we present a cryo-electron microscopy structure of full-length human Drp1 decorated on membrane tubules. Using the reconstruction of average subtracted tubular regions (RASTR) technique, we report that Drp1 forms a locally ordered lattice along the tubule without global helical symmetry. The filaments in the lattice are similar to dynamin rungs with conserved stalk interactions. Adjacent filaments are connected by GTPase domain interactions …

Assessing The Impact Of Spraying An E. Faecium Probiotic At Hatch And Supplementing Feed With A Triple-Strain Bacillus-Based Additive On Bco Lameness Incidence In Broiler Chickens, Khawla Alharbi, Anh Dang Trieu Do, Abdulaziz Alqahtani, Ruvindu Perera, Alexa Thomas, Antoine Meuter, Adnan Ali Khalaf

Poultry Science Faculty Publications and Presentations

Bacterial chondronecrosis with osteomyelitis (BCO) is a major cause of lameness in broiler chickens. This condition arises when bacteria from the gastrointestinal or aerosol tract migrate to infect bone microfractures, often exacerbated by rapid growth, reduced blood flow, and mechanical stress. As concerns about antibiotic resistance grow, probiotics have gained attention for their potential to improve gut health and reduce systemic bacterial load. This study evaluated the efficacy of a probiotic program comprising an Enterococcus faecium-based spray (2 x 10(9) CFU/bird at hatch) and a triple-strain Bacillus-based feed additive (B. subtilis 597, B. subtilis 600, and B. amyloliquefaciens 516 at …

Asymmetric Cingulum Bundle Connectivity Is Modulated By Paracingulate Sulcus Morphology, Isabel A Danstrom, Joshua A Adkinson, Meghan E Robinson, Lu Lin, Atul Maheshwari, Ben Shofty, Garrett Banks, Mohammed Hasen, Sameer A Sheth, Alica M Goldman, Eleonora Bartoli, Sarah R Heilbronner, Kelly R Bijanki

Faculty, Staff and Students Publications

The cingulum bundle (CB) is a group of axons supporting connectivity among several functional brain networks relevant in healthy and diseased states. The paracingulate sulcus (PCS) is present in at least one cerebral hemisphere across 70% of the population. PCS presence versus absence is linked to differences in structure and function of the anterior cingulate cortex, though the influence of PCS on the white matter of the CB remains unknown. The objective of this work was to define the CB electrographic connectivity profile and determine the impact of PCS morphology on CB engagement. Single-pulse electrical stimulation in combination with stereo-electroencephalography …

Finite-Temperature Kinetic Ferromagnetism In The Square-Lattice Hubbard Model, Robin C. Newby, Ehsan Khatami

Faculty Research, Scholarly, and Creative Activity

While the exact phase diagram of the Fermi-Hubbard model remains poorly understood despite decades of progress, nearly 60 years ago Nagaoka proved that a single dopant in an otherwise half-filled Hubbard system can bring about ferromagnetism through kinetic means. The phenomenon was recently observed with ultracold atoms in triangular optical lattices. Here, we explore the kinetic ferromagnetism within the square lattice Hubbard model and its strong-coupling counterpart, the t-J model, at finite temperatures in the thermodynamic limit via numerical linked-cluster expansions. We find evidence of ferromagnetic Nagaoka polarons at dopings up to ∼30% away from half filling for a variety …

Transgenerational Obesity Modulation Of Gut Mucosal Immunity, Chen-Ting Hung, Justin Kern, Tihana Trsan, Santosh K Panda, Marie Laury, Umang Jain, Marco Colonna, Thaddeus S Stappenbeck, Ta-Chiang Liu

2020-Current year OA Pubs

The prevalence of obesity in the United States has continued to increase over the past several decades. A growing concern is that transgenerational effects of obesity negatively impact physiologic functions. We showed that consumption of a high fat, high sugar "Western" diet (WD) decreased the density of both gut innate (Paneth cells) and adaptive immune cells (intraepithelial lymphocytes; IEL). We asked whether consumption of WD impacts gut mucosal immunity in the offspring. WD-mediated Paneth cell loss was reversible, whereas IEL loss was not. However, the overall composition of the fecal microbiome and response to infection were defined by the diet …

Sex Offender Prison Treatment Programs: Outdated Science Masquerading As A Legitimate Penological Objective, Shelby Jones

Penn State Journal of Law & International Affairs (2012 - Present)

No abstract provided.

Minding The Gap: The Berne Convention’S Silence On Available Copyright Infringement Damages, Kylie Johnston

Penn State Journal of Law & International Affairs (2012 - Present)

No abstract provided.

Confronting The Injustices That Prevail From Revealing Americans’ Most Private Information: Their Genetic Code, Aubrey Fleming

Penn State Journal of Law & International Affairs (2012 - Present)

No abstract provided.

Sovereignty Vs. Humanity: The Evolution Of International Law In Civil And Colonial Wars And Modern Implications, Dr. Noam Zamir

Penn State Journal of Law & International Affairs (2012 - Present)

No abstract provided.

Tax Treaties In The Wind, Doron Narotzki

Penn State Journal of Law & International Affairs (2012 - Present)

No abstract provided.

Cuba And The Constitution Of A Stable State Of Misery: Ideology, Economic Policy, And Popular Discipline, Larry Catá Backer

Penn State Journal of Law & International Affairs (2012 - Present)

No abstract provided.

Foreword

Penn State Journal of Law & International Affairs (2012 - Present)

No abstract provided.

Table Of Contents

Penn State Journal of Law & International Affairs (2012 - Present)

No abstract provided.

Dedication

Penn State Journal of Law & International Affairs (2012 - Present)

No abstract provided.

Table Of Contents, Georgia State University College Of Law

Georgia State University Law Review

No abstract provided.

Foreword, Alison M. Whelan

Georgia State University Law Review

No abstract provided.

Faculty Masthead, Georgia State University College Of Law

Georgia State University Law Review

No abstract provided.

Member Masthead, Georgia State University College Of Law

Georgia State University Law Review

No abstract provided.

Copyright Page, Georgia State University College Of Law

Georgia State University Law Review

No abstract provided.

First Inside Page, Georgia State University College Of Law

Georgia State University Law Review

No abstract provided.

Cover Page, Georgia State University College Of Law

Georgia State University Law Review

No abstract provided.

Inside Front Cover, Georgia State University College Of Law

Georgia State University Law Review

No abstract provided.

Quenching The Soul: Friendship's Vital Esence, Jennifer Diaz Villa

Night Flight: Online Literary Journal

No abstract provided.

The Gaul, Daniel Wayne Ii

Night Flight: Online Literary Journal

A short story written about a French Hussar's haunting by a Gaul from the Gallic Wars

The Nightly Curse, Thomas Cohen

Night Flight: Online Literary Journal

The Nightly Curse is a fantasy fiction following the life of Theodore Silas, who is torn between two worlds each night he falls asleep and each morning he awakens. At night, he believes that he is Elias Softstar Crystalfire, the hero of Dragon Fawn on a quest to save the realm but, at day, he is Theodore Silas. He can't tell the difference between the worlds he lives during the night and day and can't come to terms that his real identity Theodore.

Off The Beaten Trail, Jennifer Ridenour

Night Flight: Online Literary Journal

No abstract provided.

Methodological Memorandum For Michelle Llado-Wrzos' Phd Dissertation, Michelle Llado-Wrzos Ed.D., Cristo Leon Ph.D.

Journal of Roleplaying Studies and STEAM

This methodological memorandum outlines the research approach for Michelle Llado-Wrzos' PhD dissertation, which explores the underrepresentation of women in Science, Technology, Engineering, and Mathematics (STEM) fields. Despite multiple efforts to reduce the gender disparity, female students remain significantly less likely to pursue STEM majors compared to their male peers. The research focuses on assessing the impact of extrinsic motivators—specifically financial incentives and exposure to female role models—on the STEM major choices of female high school students. By adopting a mixed-methods approach, this study thoroughly integrates quantitative surveys and qualitative interviews to examine these motivators.

A quasi-experimental design will assess the …

Transmedialidad E Intertextualidad En El Caso De Five Nights At Freddy's Desde La Semiótica De La Cultura, Daira Pando Tamayo

Journal of Roleplaying Studies and STEAM

El presente artículo busca establecer, notar y delimitar que la intertextualidad y la transmedialidad juegan un papel de gran importancia al momento de crear narrativas en los videojuegos en la contemporaneidad. Enfatizando la creciente complejidad (y por lo tanto remarcando la diferencia de estructuras narrativas convencionales) que existe en las narrativas de los videojuegos y necesidad de interacción y configuración no lineal dentro de las historias de los mismos.

La Representación Del Sistema Nocional De La Estructura Bélica En Videojuegos De Multiplataforma: Una Discusión Semiótica, Alfonso Rincón Vaquero, Edgar Ávila González

Journal of Roleplaying Studies and STEAM

En este estudio de reflexión discutimos la manera en que los videojuegos de guerra multiplataforma potencialmente refuerzan estructuras de poder dominantes en la actualidad. Para ello, recurrimos a la semiótica (Eco, 1977) y, particularmente a la teoría de la segmentación de la cultura y producción de sentidos de González (2012), por medio de la cual contemplamos a los videojuegos como subespacios de la cultura que proporcionan visibilidades específicas sobre el mundo. Asimismo, nos apoyamos brevemente en la concepción del poder establecida por Michel Foucault (1978), pues llama la atención su concepción sobre las relaciones de poder como una red productiva …

Narrativas Transmedia, Fandom Y Convergencia Mediática: La Reconfiguración Contemporánea De La Industria De Los Juegos De Rol En Brasil, Diogo De Almeida Camelo

Journal of Roleplaying Studies and STEAM

Este artículo analiza cómo la industria de los juegos de rol (JDR) ha evolucionado en Brasil en respuesta a los cambios tecnológicos, culturales y económicos. El objetivo es investigar cómo la convergencia mediática, las prácticas de narrativa transmedia y el fandom han remodelado las dinámicas de producción, circulación y consumo de los juegos. La metodología utilizada fue cualitativa, fundamentada en análisis documental de fuentes primarias y en revisión histórica, con base teórica en Jenkins (2006) y Fine (1983). El estudio es parte de una tesis de maestría, y muestra que en Brasil el rol se ha transformado en un ecosistema …