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Dna Methylation Signatures Of Cardiovascular Health Provide Insights Into Diseases, Yinan Zheng, Alexis C Wood, Mengyao Wang, Chunyu Liu, Tianxiao Huan, Roby Joehanes, Xiuqing Guo, Jie Yao, Kent D Taylor, Russell P Tracy, Peter Durda, Yongmei Liu, W Craig Johnson, Wendy S Post, Tom Blackwell, Jerome I Rotter, Stephen S Rich, Susan Redline, Myriam Fornage, Jun Wang, Hongyan Ning, Lifang Hou, Donald Lloyd-Jones, Kendra Ferrier, Yuan-I Min, April P Carson, Laura M Raffield, Alexander Teumer, Hans J Grabe, Henry Völzke, Matthias Nauck, Marcus Dörr, Arce Domingo-Relloso, Amanda Fretts, Maria Tellez-Plaza, Shelley A Cole, Ana Navas-Acien, Meng Wang, Joanne M Murabito, Nancy L Heard-Costa, Brenton Prescott, Vanessa Xanthakis, Dariush Mozaffarian, Daniel Levy, Jiantao Ma Aug 2025

Dna Methylation Signatures Of Cardiovascular Health Provide Insights Into Diseases, Yinan Zheng, Alexis C Wood, Mengyao Wang, Chunyu Liu, Tianxiao Huan, Roby Joehanes, Xiuqing Guo, Jie Yao, Kent D Taylor, Russell P Tracy, Peter Durda, Yongmei Liu, W Craig Johnson, Wendy S Post, Tom Blackwell, Jerome I Rotter, Stephen S Rich, Susan Redline, Myriam Fornage, Jun Wang, Hongyan Ning, Lifang Hou, Donald Lloyd-Jones, Kendra Ferrier, Yuan-I Min, April P Carson, Laura M Raffield, Alexander Teumer, Hans J Grabe, Henry Völzke, Matthias Nauck, Marcus Dörr, Arce Domingo-Relloso, Amanda Fretts, Maria Tellez-Plaza, Shelley A Cole, Ana Navas-Acien, Meng Wang, Joanne M Murabito, Nancy L Heard-Costa, Brenton Prescott, Vanessa Xanthakis, Dariush Mozaffarian, Daniel Levy, Jiantao Ma

Faculty, Staff and Students Publications

Background: The association of overall cardiovascular health (CVH) with changes in DNA methylation (DNAm) has not been well characterized.

Methods: We calculated the American Heart Association's Life's Essential 8 score to reflect CVH in 5 cohorts with diverse backgrounds (mean age 54 years, 55% women, and enrollment year ranging from 1989 to 2012). Epigenome-wide association studies (EWAS) for Life's Essential 8 score were conducted, followed by bioinformatic analyses. DNAm loci significantly associated with Life's Essential 8 score were used to calculate a CVH DNAm score. We examined the association of the CVH DNAm score with incident cardiovascular disease (CVD), cardiovascular …


Current Practices In The Study Of Biomolecular Acondensates: A Community Comment, Simon Alberti, Paolo Arosio, Robert B Best, Steven Boeynaems, Danfeng Cai, Rosana Collepardo-Guevara, Gregory L Dignon, Rumiana Dimova, Shana Elbaum-Garfinkle, Nicolas L Fawzi, Monika Fuxreiter, Amy S Gladfelter, Alf Honigmann, Ankur Jain, Jerelle A Joseph, Tuomas P J Knowles, Keren Lasker, Edward A Lemke, Kresten Lindorff-Larsen, Reinhard Lipowsky, Jeetain Mittal, Samrat Mukhopadhyay, Sua Myong, Rohit V Pappu, Karsten Rippe, Tatyana A Shelkovnikova, Anthony G Vecchiarelli, Susanne Wegmann, Huaiying Zhang, Mingjie Zhang, Chloe Zubieta, Markus Zweckstetter, Dorothee Dormann, Tanja Mittag Aug 2025

Current Practices In The Study Of Biomolecular Acondensates: A Community Comment, Simon Alberti, Paolo Arosio, Robert B Best, Steven Boeynaems, Danfeng Cai, Rosana Collepardo-Guevara, Gregory L Dignon, Rumiana Dimova, Shana Elbaum-Garfinkle, Nicolas L Fawzi, Monika Fuxreiter, Amy S Gladfelter, Alf Honigmann, Ankur Jain, Jerelle A Joseph, Tuomas P J Knowles, Keren Lasker, Edward A Lemke, Kresten Lindorff-Larsen, Reinhard Lipowsky, Jeetain Mittal, Samrat Mukhopadhyay, Sua Myong, Rohit V Pappu, Karsten Rippe, Tatyana A Shelkovnikova, Anthony G Vecchiarelli, Susanne Wegmann, Huaiying Zhang, Mingjie Zhang, Chloe Zubieta, Markus Zweckstetter, Dorothee Dormann, Tanja Mittag

Duncan NRI Faculty and Staff Publications

The realization that the cell is abundantly compartmentalized into biomolecular condensates has opened new opportunities for understanding the physics and chemistry underlying many cellular processes, fundamentally changing the study of biology. The term biomolecular condensate refers to non-stoichiometric assemblies that are composed of multiple types of macromolecules in cells, occur through phase transitions, and can be investigated by using concepts from soft matter physics. As such, they are intimately related to aqueous two-phase systems and water-in-water emulsions. Condensates possess tunable emergent properties such as interfaces, interfacial tension, viscoelasticity, network structure, dielectric permittivity, and sometimes interphase pH gradients and electric potentials–. …


Promising Practices To Address Healthcare Needs Voiced By Local Native Americans, Noelle Taylor, Mykin R. Higbee, Raiden Gaul Aug 2025

Promising Practices To Address Healthcare Needs Voiced By Local Native Americans, Noelle Taylor, Mykin R. Higbee, Raiden Gaul

Transforming Communities

Purpose

To examine barriers and facilitators to nursing education among Native Americans and identify evidence-based strategies to increase the number of Native American nurses working in their local communities to address health disparities.

Background

Native Americans experience significantly higher rates of chronic illnesses such as diabetes and heart disease, and lower life expectancies. Only 4% of registered nurses identify as Native American, with no growth despite increased funding for diversity in nursing education. This underrepresentation contributes to culturally insensitive care and persistent healthcare inequities stemming from historical marginalization and trauma.

Methods

A comprehensive literature review was conducted using CINAHL, PubMed, …


Use Of Ict In South African Schools And The Plight Of Marginalized Learners During The Covid-19 Pandemic, Chinegbonkpa Hope Nwakanma, Maryam Chinasa Adewunmi Aug 2025

Use Of Ict In South African Schools And The Plight Of Marginalized Learners During The Covid-19 Pandemic, Chinegbonkpa Hope Nwakanma, Maryam Chinasa Adewunmi

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Given that information and communication technology is still a luxury for poor students, especially in developing countries like South Africa. It is crucial to examine the extent of the inequalities and social marginalisation learners face due to lack of access to ICT, as well as the impact on their learning. This study, therefore, explores the use of ICT in public schools by synthesising existing literature on its effect on the teaching and learning of socially and economically marginalised learners. Using the qualitative research approach involving document analysis and literature review, this study reveals that lack of resources, skills and the …


Influence Of Self-Confidence, Practice Experience, Learning Outcomes Enterpreneur's Practices And Soul Towards Entrepreneurial Capability Cash Design Vocational Students, Wulidah Ning Tiasari, Tuwoso Tuwoso, Agus Hery Supadmi Irianti, Mingchang Wu Aug 2025

Influence Of Self-Confidence, Practice Experience, Learning Outcomes Enterpreneur's Practices And Soul Towards Entrepreneurial Capability Cash Design Vocational Students, Wulidah Ning Tiasari, Tuwoso Tuwoso, Agus Hery Supadmi Irianti, Mingchang Wu

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This research aims to find out whether there is a significant simultaneous influence of self-confidence, practical experience, practical learning outcomes, entrepreneurial spirit on the entrepreneurial abilities of Fashion Design Vocational School students in Malang City. In this study, the sample of respondents was 134 students using quantitative methods. The analysis technique uses descriptive and inferential with hypothesis testing using partial correlation and multiple regression analysis techniques with classic assumption tests, namely normality test, linearity test, multicollinearity test, autocorrelation test and heteroscedasticity test. The research is quantitative descriptive in nature. The results of the research show the influence of independent variables, …


Pengaruh Model Challenge Based Learning Terhadap Keterampilan Berpikir Kritis Dan Hasil Belajar Siswa Pada Materi Bencana Alam Kelas V Sd, Elfa Diyah Kusuma, M. Anas Thohir, Lilik Bintartik Aug 2025

Pengaruh Model Challenge Based Learning Terhadap Keterampilan Berpikir Kritis Dan Hasil Belajar Siswa Pada Materi Bencana Alam Kelas V Sd, Elfa Diyah Kusuma, M. Anas Thohir, Lilik Bintartik

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Salah satu kemampuan yang sangat penting untuk pembelajaran di era modern adalah pemikiran kritis. Tujuan penelitian ini adalah untuk mengevaluasi bagaimana model pembelajaran berbasis tantangan berdampak pada keterampilan berpikir kritis siswa dan hasil belajar mereka tentang materi bencana alam di kelas V SD. Eksperimen semu (Quasi Exprimental Design) digunakan dengan tipe pre-test dan post-test Grup Kontrol NonEquivalen. Penelitian ini melibatkan 44 siswa kelas V SD dari dua kelas yang sama. Dalam penelitian ini, seluruh siswa kelas V SD diambil sebagai sampel. Metode pengumpulan data dengan menggunakan tes pilihan ganda dan esai. Uji MANOVA digunakan untuk menganalisis data. Hasil uji statistik …


Analysis Of Students’ Spatial Ability Using Geogebra In The Spatial Geometry Course, Nurma Izzati, Reo Al Farizi Aug 2025

Analysis Of Students’ Spatial Ability Using Geogebra In The Spatial Geometry Course, Nurma Izzati, Reo Al Farizi

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This study aims to analyze the spatial ability of students using GeoGebra in solving students' spatial ability problems in the spatial geometry course. The research method used is a descriptive qualitative method. The instrument used is a spatial ability test of spatial geometry which is arranged based on spatial ability indicators, namely visualization, spatial perception, mental rotation, spatial relation, and spatial orientation. The research subjects were all students of the Mathematics Department of the Faculty of Tarbiyah and Teacher Training (FITK) semester 3 classes A and B of the State Islamic University of Cyber Syekh Nurjati Cirebon (UIN SSC) totaling …


Penyamaan Persepsi Guru Dalam Pengembangan Mentoring Skills Berbasis Lms Untuk Pembimbingan Mahasiswa Ppl Ppg Prajabatan, Zihan Novita Sari, Herlina Ike Oktaviani, Paundra Wangsa Fajar Kusuma Aug 2025

Penyamaan Persepsi Guru Dalam Pengembangan Mentoring Skills Berbasis Lms Untuk Pembimbingan Mahasiswa Ppl Ppg Prajabatan, Zihan Novita Sari, Herlina Ike Oktaviani, Paundra Wangsa Fajar Kusuma

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Praktik Pengalaman Lapangan (PPL) dalam Pendidikan Profesi Guru (PPG) memiliki peran penting dalam membekali calon guru dengan keterampilan mengajar. Guru pamong memiliki peran penting dengan bertindak sebagai mentor yang membimbing mahasiswa PPL. Namun, terdapat perbedaan pemahaman di kalangan guru pamong terkait konsep mentoring yang menyebabkan ketidakkonsistenan dalam pembimbingan. Oleh karena itu, penelitian ini bertujuan untuk menjabarkan peran Learning Management System (LMS) dalam mendukung pembimbingan mahasiswa PPL PPG, mengidentifikasi tantangan dalam implementasinya, serta memahami persepsi guru pamong terhadap keterampilan mentoring. Penelitian ini menggunakan pendekatan mixed-method dengan desain deskriptif eksploratif. Data dikumpulkan melalui survei dengan angket, wawancara mendalam dengan guru pamong, serta …


“Wild Things Belong Outside”: An Ecofeminist Analysis Of Amy Greene’S Bloodroot, Karrah N. Davidson Aug 2025

“Wild Things Belong Outside”: An Ecofeminist Analysis Of Amy Greene’S Bloodroot, Karrah N. Davidson

Critical Humanities

Appalachian Literature has a canon of its own, one of which I believe Amy Greene’s groundbreaking novel, Bloodroot should be a more prominent part. The novel brings up important cultural as well as universal issues. Situating this work among relevant theory and scholarship allows us to think seriously about the themes that Green explores in the novel in a way that has not been done before. Additionally, I believe that there is important scholarly work to be done with the role of Appalachian Folk Magic in a world where some of these traditions and customs are dying out. Individuals within …


Three New Species Of Androctonus From Morocco (Arachnida: Scorpiones: Buthidae), František Kovařík, Graeme Lowe, František Šťáhlavský Aug 2025

Three New Species Of Androctonus From Morocco (Arachnida: Scorpiones: Buthidae), František Kovařík, Graeme Lowe, František Šťáhlavský

Euscorpius

New data are presented on the taxonomy and distribution of the dark species of the genus Androctonus Ehrenberg, 1828 in Morocco and Western Sahara. Three new species, A. argoubi sp. n., A. stockmanni sp. n., and A. vaneki sp. n. from Morocco are described, characterized by having metasoma I–IV ventrally punctate, a character that is well developed in A. stockmanni sp. n., and A. vaneki sp. n., and weakly developed in A. argoubi sp. n. Dark species from Morocco are compared with A. sergenti Vachon, 1948, and A. bourdoni Vachon, 1948. We describe and compare their …


Validity And Reliability Of The 'Feelfit®' Accelerometer In Evaluating Physical Activity And Sedentary Time In Children: A Comparative Study With Two Different Accelerometers, Songdhasn Chinapong, Korntawat Klinchan, Hanif Abdul Rahman, Michael Chia, Waris Wongpipit, Jetsada Arnin, Areekul Amornsriwatanakul Aug 2025

Validity And Reliability Of The 'Feelfit®' Accelerometer In Evaluating Physical Activity And Sedentary Time In Children: A Comparative Study With Two Different Accelerometers, Songdhasn Chinapong, Korntawat Klinchan, Hanif Abdul Rahman, Michael Chia, Waris Wongpipit, Jetsada Arnin, Areekul Amornsriwatanakul

International Journal of Exercise Science

International Journal of Exercise Science 18(2): 794-810, 2025. Accurate physical activity (PA) measurement is crucial for public health surveillance. While self-report questionnaires are commonly used, they have limitations, especially in young children. An affordable and user-friendly device like Feelfit® offers a promising alternative particularly for countries with limited research resources. This study aimed to evaluate Feelfit®’s performance against the widely used ActiGraph® accelerometer in measuring PA among children. A quasi-experimental design was applied. Thirty-nine children (19 boys; 20 girls; aged 11.4 ± 0.5 years) wore both Feelfit® and ActiGraph® during sequentially specified activities of varying intensity ranging from sedentary to …


The Shorthorn: April 28, 1977 Aug 2025

The Shorthorn: April 28, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 29, 1977 Aug 2025

The Shorthorn: April 29, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 26, 1977 Aug 2025

The Shorthorn: April 26, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 27, 1977 Aug 2025

The Shorthorn: April 27, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 22, 1977 Aug 2025

The Shorthorn: April 22, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 21, 1977 Aug 2025

The Shorthorn: April 21, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 20, 1977 Aug 2025

The Shorthorn: April 20, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 15, 1977 Aug 2025

The Shorthorn: April 15, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 19, 1977 Aug 2025

The Shorthorn: April 19, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 14, 1977 Aug 2025

The Shorthorn: April 14, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 13, 1977 Aug 2025

The Shorthorn: April 13, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 12, 1977 Aug 2025

The Shorthorn: April 12, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: April 1, 1977 Aug 2025

The Shorthorn: April 1, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: March 30, 1977 Aug 2025

The Shorthorn: March 30, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: March 31, 1977 Aug 2025

The Shorthorn: March 31, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: March 29, 1977 Aug 2025

The Shorthorn: March 29, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: March 24, 1977 Aug 2025

The Shorthorn: March 24, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: March 25, 1977 Aug 2025

The Shorthorn: March 25, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.


The Shorthorn: March 23, 1977 Aug 2025

The Shorthorn: March 23, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.