Digital Commons Network^™

Afro-Caribean Student Association, University Of Mississippi. Afro-Caribbean Student Association

University Website Migration from WordPress

No abstract provided.

Plato Program, University Of Mississippi. Academic Innovation Group

University Website Migration from WordPress

No abstract provided.

Macular Thinning And Microvasculature Abnormalities In Children With Sickle Cell Disease: A Longitudinal Analysis, Sally S. Ong, Ann Nampomba, Sara Rahman, Loka Thangamathesvaran, Grace Reilly, Jianqiao Ma, Jay Vaidya, Sophie Lanzkron, Adrienne W. Scott

Cardeza Foundation for Hematologic Research

PURPOSE: To assess longitudinal changes in retinal thickness and vessel density (VD) in pediatric sickle cell disease (SCD).

DESIGN: A prospective cohort study.

PARTICIPANTS: Children (< 18 years old) with HbSS and HbS variant (HbSC and HbS thalassemia) genotypes were enrolled from a university-based retina subspecialty clinic from 2017 to 2019 and followed for ≥2 years.

METHODS: Participants received 3 × 3 and 6 × 6 mm OCT and OCT angiography scans at baseline and at each follow-up visit.

MAIN OUTCOME MEASURES: Retinal thickness, superficial capillary plexus (SCP), and deep capillary plexus (DCP) VD were compared over time.

RESULTS: Children with HbSS (n = 14) and HbS variant (n = 14) genotypes with ≥1 follow-up were included in the study (total 56 eyes). For HbSS, rates of retinal thinning per …

Religious Identity, Linked Fate, And Political Ideology: Explaining Civil Rights Philanthropy Among Muslim And Jewish Americans, Rafeel Wasif, Afshan Paarlberg, Shariq Siddiqui, David King

Public Administration Faculty Publications and Presentations

Social identity theory predicts that individuals prefer to give to people with the same identity as themselves. However, individuals have multiple identities that interact simultaneously. For instance, religion is an essential identity for many individuals, particularly those from racialized minority groups, such as Muslims and Jews, who are often discriminated against due to these identities. Moreover, individuals like to support faith-based causes. However, they may also feel that they have a linked fate identity, where they perceive a commonality with other persecuted minorities due to similar experiences of discrimination. Moreover, political ideology is another vital identity marker for many individuals. …

Ayyakkannu Manivannan V. Doe

2025 Decisions

USDC for the Western District of Pennsylvania

Thomas Traumann V. James Funt

2025 Decisions

USDC for the Eastern District of Pennsylvania

Sergei Kovalev V. Walmart Inc

2025 Decisions

USDC for the Eastern District of Pennsylvania

Autistic Traits In Fibromyalgia Are Associated With Hypersensitivity And Central Sensitisation, Helen Johnston, Alison Bacon

School of Psychology

Fibromyalgia presents with symptoms of central sensitisation (CS). Allodynia is the defining symptom, with evidence for general hypersensitisation extending beyond the pain symptoms that characterise fibromyalgia, to sensory and psychological domains. Generalised sensory processing sensitivity (SPS) may increase vulnerability to hypersensitisation; while a direct association exists between sensory sensitivity and autistic traits in autistic people, CS symptoms are also associated with autistic traits in a broader participant sample. This study complements previous lines of enquiry by examining the relationship between SPS, CS symptoms and autistic traits in samples with and without fibromyalgia. It proposes that SPS is indirectly associated with …

Molecular Landscape Of Sex- And Modality-Specific Exercise Adaptation In Human Skeletal Muscle Through Large-Scale Multi-Omics Integration, Macsue Jacques, Shanie Landen, Adam P. Sharples, Andrew Garnham, Ralf Schittenhelm, Joel Steele, Aino Heikkinen, Elina Sillanpää, Miina Ollikainen, James Broatch, Navabeh Zarekookandeh, Ola Hanson, Ola Ekström, Olof Asplund, Séverine Lamon, Sarah E. Alexander, Cassandra Smith, Carlie Bauer, Mary N. Woessner, Itamar Levinger, Andrew E. Teschendorff, Linn Gillberg, Ida Blom, Jørn Wulff Helge, Nicholas Harvey, Larisa M. Haupt

Research outputs 2022 to 2026

We investigated the molecular mechanisms of exercise adaptations in human muscle by integrating genome, methylome, transcriptome, and proteome data from over 1,000 participants (2,340 muscle samples). We identified distinctive signatures associated with maximal oxygen consumption (VO2max), and multi-omics integration uncovered five key genes as robust exercise markers across layers, with transcription factors functioning as activators, synergizing with DNA methylation to regulate gene expression. Minimal sex differences were observed, while modality-specific analysis highlighted distinct pathways for aerobic and resistance exercise, contrasting with muscle disuse patterns. Finally, we created a webtool, OMAx, featuring our individual omics and integration analysis. These findings provide …

Hegemonic Entrepreneurial Masculinities In Patriarchal Contexts: Exploring Men's Entrepreneurship In War-Torn Territories, Doaa Althalathini, Theodore A. Khoury, Nick Rumens

Business Faculty Publications and Presentations

This article examines how the war-torn context in Iraq has affected men’s entrepreneurship and entrepreneurial masculinities. Drawing on the entrepreneurship masculinities literature, Connell’s notion of hegemonic masculinity and in-depth interviews with 21 Iraqi men entrepreneurs, this article demonstrates the complex interplay between entrepreneurship, masculinity and patriarchal dynamics in the context of wars and economic instability in Iraq. Study findings show how Iraqi men often turn to entrepreneurship out of necessity to meet patriarchal expectations of them as primary providers for their families. We contribute to the literature on entrepreneurship, men and masculinities by demonstrating how entrepreneurship not only serves as …

Quality Improvement Project Reducing Pediatric Anesthesia In Magnetic Resonance Imaging: The Role Of Preparedness And Education, Rachel Turner

Doctor of Nursing Practice Projects

Pediatric hematology-oncology patients undergo general anesthesia (GA) for various medical procedures, including magnetic resonance imaging (MRI) scans. Overexposure to GA increases the potential for long-term neurocognitive effects in pediatric patients. Despite the growing research literature on GA-related neurotoxicity and the Food and Drug Administration's (FDA) warnings, advanced practice providers (APP) often lack the knowledge to advocate for and support reductions in pediatric GA use. The Doctor of Nurse Practice (DNP) quality improvement (QI) project aimed to reduce unnecessary GA in pediatric hematology-oncology patients undergoing MRI scans by addressing the primary clinic APPs' knowledge deficits through interprofessional education (IPE). Structured in …

Did You Clean It? - An Evidence-Based Project To Improve Environmental High Touch Area Cleaning Practices, Lauren Hagglund, Hailey Holt, Ainsley Ingebrigtsen, Emily Keller, Stuti Khadka, Kit Mallari, Gavin Martinez, Sahira Monroy, Hannah Pendarvis, T.A. Stockton

2024

No abstract provided.

Yucky Mouth? Clean It Up., Alexandra Thomson, Catherine Barry, Katie Spallo, Sabreen Al Bashiti, Chandler Conerly, Linda Smith

2024

No abstract provided.

Fostering Bright Beginnings: Exploring The Impact Of Cycled Ambient Lighting On Neurological Outcomes Of Infants In A Level Iv Nicu, Julie Acton, Cameron Hartnett, Abeni Kratzmeyer, Grace Madrinan, Elicha Saunders, Alexis Serrano, Morgan Van Der Weert, Erin Wood

2024

No abstract provided.

Do You Have A Second? Nurse Interruptions And Medication Errors, Beaux Brownlow, Camryn Fleming, Sarah Jermstad, Lydia Moore, Nicole Rickert, Sydney Snyder

2024

No abstract provided.

Increasing Safe Sleep Compliance Among Caregivers & Staff, Alexandra Dyer, Rupanpreet Kaur, Hannah Mueller, Alexis Olivares, Haley Payne, Nancy Silva, Julianna Sicilian, Krista Valencia

2024

No abstract provided.

Burning Questions: All About Fevers, Lauren Bowen, Julia Dyer, Janeth Castillo Hernandez, Coral Lucas

2024

No abstract provided.

The Effects Of Bedside Handoff In The Pediatric Emergency Department, Kristina Aryee, Haleigh Hogan, Ainsley Knight, Kelsey Matas, Garrett Matlock

2024

No abstract provided.

Rolling With The Bss: Standardizing Stool Assessments In Pediatric Care, Herlinda Cardenas Arce, Allison Hoffman, Hannah Holmes, Sierrah Martinez, Cinthya Mondragon

2024

No abstract provided.

Implementation Of I-Shaped Nursing Hand-Off To Improve Nurse Hand-Off Satisfaction, Layla Awad, Denise Hood, Octavia Sandifer

2024

No abstract provided.

Preventing Nurse Burnout And Improving Retention Rates, Abigail Rannow, Kayla Bernius, Camellia Le, Stephanie Cardenas Parra, Cesar Lopez

2024

No abstract provided.

No More Line Mix-Ups: The Label Solution, Alexis Spain, Holly Mckeethan, Lindsey Garvey, Molly Andersen, Natalie Romei, Catherine Fritz, Abigail Munoz, Kc Chamberlain

2024

No abstract provided.

Improving Ambulation And Safety Related To Complex Medical Equipment In Inpatient Settings, Kellie Chin, Allie Fox, Destiny Gaines, Luke Hernandez, Natalie Kauppila, Taylor Potraza

2024

No abstract provided.

From Bed To Better: An Interdisciplinary Approach To Establish Early Mobility & Routine Among Pediatric Hematology Oncology Patients, Emerson Emerson, Kayla Boxer, Kennedi Mcclain, Kylie Hollander, Mckenna Landon, Shannon Wheeler

2024

No abstract provided.

Cancer Therapeutic Compositions And Methods Targeting Dnaseil3, Michael J. Gough, Marka R Crittenden, Tiffany Blair

Technology Transfer - Patents

No abstract provided.

Physiological Role And Mechanisms Of Action For A Long Noncoding Haplotype Region., Hong Xue, Manoj K Mishra, Yong Liu, Pengyuan Liu, Michael Grzybowski, Rajan Pandey, Kristie Usa, Mark A Vanden Avond, Niharika Bala, Abdel A Alli, Allen W Cowley, Qiongzi Qiu, Andrew S Greene, Sridhar Rao, Caitlin C O'Meara, Aron M Geurts, Mingyu Liang

Faculty Research 2025

Direct targeting of noncoding genomic regions harboring common sequence variants associated with human traits through in vivo animal model studies and precise genome editing in human cells is essential for closing the critical gap between genetic discoveries and physiological understanding. However, such investigation has been impractical for many of these variants as they are in haplotypes containing multiple single-nucleotide polymorphisms (SNPs) spanning thousands of base pairs and have small effect sizes. We developed an integrated approach to address this challenge, combining an efficient two-step technique to precisely edit large haplotypes in human induced pluripotent stem cells and orthologous region deletion …

Immunosuppressive Tumor Microenvironment Of Osteosarcoma., Aaron M Taylor, Jianting Sheng, Patrick Ks Ng, Jeffrey M. Harder, Parveen Kumar, Ju Young Ahn, Yuliang Cao, Alissa M Dzis, Nathaniel L. Jillette, Andrew Goodspeed, Avery Bodlak, Qian Wu, Michael S Isakoff, Joshy George, Jessica D S Grassmann, Diane Luo, William F Flynn, Elise T Courtois, Paul Robson, Masanori Hayashi, Alini Trujillo Paolillo, Antonio Sergio Petrilli, Silvia Regina Caminada De Toledo, Fabiola Sara Balarezo, Adam D Lindsay, Bang Hoang, Stephen T C Wong, Ching C Lau

Faculty Research 2025

Background/Objectives: Osteosarcoma is the most common malignant bone tumor in children, characterized by a high degree of genomic instability, resulting in copy number alterations and genomic rearrangements without disease-defining recurrent mutations. Clinical trials based on molecular characterization have failed to find new effective therapies or improve outcomes over the last 40 years. Methods: To better understand the immune microenvironment of osteosarcoma, we performed single-cell RNA sequencing on six tumor biopsy samples, combined with a previously published cohort of six samples. Additional osteosarcoma samples were profiled using spatial transcriptomics for the validation of discovered subtypes and to add spatial context. Results: …

Diversity, Equity, And Inclusion Under Siege Worldwide: Moving Beyond Limiting Notions Of Gender And Sexuality In Education Organizations And Leadership, Margaret Grogan

Education Faculty Books and Book Chapters

As 2025 gets underway in the United States, educators across this country, like in many others, are bracing for unprecedented opposition to their diversity, equity, and inclusion (DEI) programs and policies. Newly elected President Trump is rapidly dismantling many federal agencies, cutting off aid to foreign entities, and causing major apprehension across the globe. His stated agenda to eradicate progressivism echoes many other international ultraconservative and far-right movements, who applaud his authoritarian regime. To mount the best possible resistance to these disturbing developments, and, indeed, to expand and strengthen DEI work, this chapter argues for collective action across all the …

The Brief (Edition #39, June 2025), William & Mary Law School

The Brief

No abstract provided.

7 Questions With Dr. Bear Jiang, University Of Dayton

Blog: The Dayton Engineer

We sat down with Dr. Bear Jiang, post-doc to tenure track fellow in the Department of Civil and Environmental Engineering and Engineering Mechanics, to learn more about his career and research.