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Articles 16321 - 16350 of 5203848
Full-Text Articles in Entire DC Network
Conviction, Character, Courage: The Case For Integrating Values Into The Professional Identity Formation Of Tomorrow's Lawyer-Leaders, Katya S. Cronin
Conviction, Character, Courage: The Case For Integrating Values Into The Professional Identity Formation Of Tomorrow's Lawyer-Leaders, Katya S. Cronin
Journal of Legal Education
No abstract provided.
Moral Virtues, Professional Identity, And Leadership, Timothy W. Floyd
Moral Virtues, Professional Identity, And Leadership, Timothy W. Floyd
Journal of Legal Education
No abstract provided.
The Large Impact Of Small Groups On The Character-Based Leadership Development Of Law Students, Benjamin Rigney, Janice Craft
The Large Impact Of Small Groups On The Character-Based Leadership Development Of Law Students, Benjamin Rigney, Janice Craft
Journal of Legal Education
No abstract provided.
Book Review Of The Lawyer Nation: The Past, Present, And Future Of The American Legal Profession, Jennifer A. Gundlach
Book Review Of The Lawyer Nation: The Past, Present, And Future Of The American Legal Profession, Jennifer A. Gundlach
Journal of Legal Education
No abstract provided.
Profiling Arbutin As A Potent Cholinesterase And Gsk-3Β Inhibitor And Evaluating Its Cytotoxicity In Sh-Sy5y Cells For Alzheimer’S Disease Therapy, Shirin Tarbiat, Tuğba Bal, Deni̇z Gülmez
Profiling Arbutin As A Potent Cholinesterase And Gsk-3Β Inhibitor And Evaluating Its Cytotoxicity In Sh-Sy5y Cells For Alzheimer’S Disease Therapy, Shirin Tarbiat, Tuğba Bal, Deni̇z Gülmez
Turkish Journal of Biology
Background/aim: Alzheimer’s disease (AD) is a neurodegenerative disorder linked to cognitive decline and memory loss, marked by hyperphosphorylated tau tangles and decreased acetylcholine levels, which are affected by acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity. Glycogen synthase kinase-3 beta (GSK-3β) also plays a role in AD through abnormal activation. In this study, the potential of β-arbutin to inhibit cholinesterases and GSK-3β was investigated, utilizing in vitro assays, cytotoxicity analysis, and molecular docking simulations to explore its therapeutic implications.
Materials and methods: Ellman’s technique was used to test the inhibitory effects of arbutin on cholinesterase enzymes. An ATP-Glo luminescent assay kit was …
Probiotic Intervention In Colorectal Cancer: The Cytotoxic And Apoptotic Potential Of Lactobacillus Cell-Free Supernatants, Bahar Yilmaz, Berna Erdal
Probiotic Intervention In Colorectal Cancer: The Cytotoxic And Apoptotic Potential Of Lactobacillus Cell-Free Supernatants, Bahar Yilmaz, Berna Erdal
Turkish Journal of Biology
Background/aim: Failures in the treatment of colorectal cancer (CRC) have increased scientific interest in the potential of the bioactive compounds contained in cell-free supernatants (CFSs) obtained from probiotic bacteria for cancer treatment. The aim in this study was to investigate the effects of CFSs obtained from Lactobacillus delbrueckii subsp. bulgaricus (L. bulgaricus) and Lactobacillus paracasei subsp. paracasei (L. paracasei) on colorectal cancer cell lines (HT-29 and Caco-2) and a healthy colon epithelial cell line (CCD841 CoN).
Materials and methods: Cytotoxic effects on the cell lines were determined by MTT assay. In line with the IC50 values obtained, morphological changes were …
Antiatopic Dermatitis Activity Of Lissachatina Fulica Mucin: Network Pharmacology Analysis And Experimental Validation, Atin Supiyani, Wasmen Manalu, Lina Noviyanti Sutardi, Mawar Subangkit, Andriyanto Andriyanto
Antiatopic Dermatitis Activity Of Lissachatina Fulica Mucin: Network Pharmacology Analysis And Experimental Validation, Atin Supiyani, Wasmen Manalu, Lina Noviyanti Sutardi, Mawar Subangkit, Andriyanto Andriyanto
Turkish Journal of Biology
Background/aim: Lissachatina fulica mucin (LFM) has been used as a nutraceutical, therapeutic agent, and cosmetic ingredient. The bioactivity of mucin depends on bioactive compounds whose composition is strongly influenced by the snail’s diet. This study investigated the bioactive compounds in L. fulica mucin as potential therapeutic agents for atopic dermatitis (AD).
Materials and methods: LFM was collected from snails fed long beans and melon rinds for 4 weeks, freeze-dried, and analyzed using liquid chromatography–mass spectrometry followed by network pharmacology (NP) analysis to identify its bioactive compounds. A total of 60 BALB/c mice were sensitized on the dorsal skin with 1% …
The N-Terminal, Wd40, And C-Terminal Domains Of Wdr-31 Control Ciliary Localization And Cooperate With Elmod/Rp2 Gaps To Maintain Membrane Compartmentalization, Sebi̇ha Çevi̇k, Fatma Güzel
The N-Terminal, Wd40, And C-Terminal Domains Of Wdr-31 Control Ciliary Localization And Cooperate With Elmod/Rp2 Gaps To Maintain Membrane Compartmentalization, Sebi̇ha Çevi̇k, Fatma Güzel
Turkish Journal of Biology
Background/aim: WD40 repeats are found in many ciliary proteins. Although the WD40 repeat-containing WD repeat-containing protein 31 (WDR-31) is known to regulate ciliary protein trafficking and morphology, the specific contributions of its N-terminal, WD40, and C-terminal domains to protein localization and ciliary gate integrity remain unclear. Aim of this study is to dissect the functional roles of WDR-31 domains by investigating their contributions to ciliary localization, ciliary protein trafficking, and gate integrity.
Materials and methods: Using CRISPR/Cas9 technology, we generated Caenorhabditis elegans strains with in-frame deletions that removed the N-terminus (WDR-31(ΔN)), WD40 (WDR-31(ΔWD)), and C-terminus (WDR-31(ΔC)). We next examined the …
Discovery And Functional Characterization Of Novel Programmed Death-Ligand 1 Monoclonal Antibodies, Nurşah Ersezen, Mai̇de Şeker, Arzu Aysan, Durmuş Akdoğan, Mehmet Ender Avci, Asli Kurden Pekmezci̇, Si̇bel Kalyoncu Uzunlar, Mehmet İnan, Tamer Yağci
Discovery And Functional Characterization Of Novel Programmed Death-Ligand 1 Monoclonal Antibodies, Nurşah Ersezen, Mai̇de Şeker, Arzu Aysan, Durmuş Akdoğan, Mehmet Ender Avci, Asli Kurden Pekmezci̇, Si̇bel Kalyoncu Uzunlar, Mehmet İnan, Tamer Yağci
Turkish Journal of Biology
Background/aim: Targeted therapies with monoclonal antibodies provide cancer patients with better prognosis and diseasefree survival. The blockade of immune checkpoints, including programmed cell death protein-1 (PD-1) and its ligand PD-L1, with monoclonal antibodies may boost immune responses against tumors and is regarded as an effective strategy in cancer immunotherapy. We describe the generation of anti-PD-L1 monoclonal antibodies with high affinity and specificity, and we assess their potential for therapeutic use in cancer.
Materials and methods: Hybridomas were selected for PD-L1 specificity and cross-reactivity with other immune checkpoint proteins and PD-L1 orthologs using indirect ELISA. Immunofluorescence and Western blotting assays were …
Dwight Davis V. Secretary Us Department Of Homeland Security
Dwight Davis V. Secretary Us Department Of Homeland Security
2026 Decisions
USDC for the District of New Jersey
William Webb, Jr. V. Kirk Neal
William Webb, Jr. V. Kirk Neal
Lineage Tracing Reveals A Shared Cellular Origin For Supraclavicular Brown And Inguinal Beige Adipocytes, Yali Ran, Kai Zhang, Yi-Ting Shen, Qianxing Mo, Ziyi Wang, Hari Krishna Yalamanchili, Sharon John, Mari Kogiso, Xia Gao, Chunmei Wang, Tanvi Sinha, Brian L Black, Miao-Hsueh Chen
Lineage Tracing Reveals A Shared Cellular Origin For Supraclavicular Brown And Inguinal Beige Adipocytes, Yali Ran, Kai Zhang, Yi-Ting Shen, Qianxing Mo, Ziyi Wang, Hari Krishna Yalamanchili, Sharon John, Mari Kogiso, Xia Gao, Chunmei Wang, Tanvi Sinha, Brian L Black, Miao-Hsueh Chen
Duncan NRI Faculty and Staff Publications
The metabolic importance of brown adipose tissue (BAT) has been recognized, but its origins, particularly supraclavicular BAT (scBAT), remain unclear. Here, we traced scBAT to Mef2c-anterior heart field (AHF)-marked cells. Mef2c-AHF-marked cells isolated from scBAT can spontaneously differentiate into brown adipocytes, express mesenchymal stem cell markers, and can be isolated from the stromal-vascular fraction (SVF) of wild-type scBAT as [CD31
Frailty As A Framework To Understand Tuberculosis Severity, Recovery, And Sequelae, Yoscelina Estrella Martinez-Lopez, Benjamin W. Black, Jessica Lee, Brian J. Buta, Lisa Y. Armitige, William A. Fountain, Rafael Samper, Aanand D. Naik, Joanne Turner, Blanca I. Restrepo
Frailty As A Framework To Understand Tuberculosis Severity, Recovery, And Sequelae, Yoscelina Estrella Martinez-Lopez, Benjamin W. Black, Jessica Lee, Brian J. Buta, Lisa Y. Armitige, William A. Fountain, Rafael Samper, Aanand D. Naik, Joanne Turner, Blanca I. Restrepo
School of Medicine Publications
Tuberculosis (TB) causes profound systemic illness, and many survivors experience long-term sequelae associated with disability and premature mortality. Current TB severity indicators capture isolated aspects of disease and may not reflect the integrated physiological impact of infection on the host. Frailty, a multidimensional syndrome characterized by reduced physiological reserve and increased vulnerability to stressors, predicts adverse outcomes and guides clinical management in geriatrics. We propose frailty as an integrative framework for understanding the systemic effects of TB across the life course, encompassing disease severity, recovery, and long-term sequelae. We discuss biological mechanisms through which Mycobacterium tuberculosis infection may erode physiological …
Low-Temperature Co2-Enhanced Reductive Bioleaching For Selective Nickel Recovery From Iron-Rich Silicate Tailings, With Concurrent Carbon Sequestration, Kwabena Boafo, Palas Kamlakar Borkar, Atharva Rane, Timothy Eisele
Low-Temperature Co2-Enhanced Reductive Bioleaching For Selective Nickel Recovery From Iron-Rich Silicate Tailings, With Concurrent Carbon Sequestration, Kwabena Boafo, Palas Kamlakar Borkar, Atharva Rane, Timothy Eisele
Michigan Tech Publications
Recovering nickel from iron-rich mine tailings by bioleaching is held back by the co-dissolution of iron, which gives pregnant leach solutions with high Fe/Ni mass ratios and heavy downstream purification costs. This study shows that running bioleaching at 0 °C under a CO2-enriched atmosphere, with no post-leach iron removal step, lowers the Fe/Ni mass ratio in the leachate from 13.87 at 25 °C to 2.25 at 0 °C, a 6.2-fold improvement against a feed Fe/Ni ratio of 119:1. Nickel recovery stayed near 45% at both temperatures, showing that the fen-derived psychrotolerant consortium remained fully active near freezing. The mechanism rests …
Electronic Structure Discretization And Compression Using Diagonal Basis Sets, Casey Lee Dowdle
Electronic Structure Discretization And Compression Using Diagonal Basis Sets, Casey Lee Dowdle
Dartmouth College Ph.D Dissertations
Numerically solving the electronic structure problem is a fundamentally difficult problem due to the exponential growth in the dimension of the Hilbert space as the system size increases. In order to solve problems at a chemically relevant accuracy, both the choice of basis set and numerical method are important factors that are intrinsically connected.
In this thesis, we study the discretization and resulting compression of electronic Hamiltonians using diagonal basis sets. A diagonal basis set approximately diagonalizes the matrix and tensor representations of the one- and two-body potentials. This can reduce storage, simplify matrix-vector products, and lower the complexity of …
Advancing Maternal Health Equity In Nebraska: Examining Prenatal Care Access Disparities, Policy Context, And Doula Integration As A Complementary Solution, Marlette Grace Dulcinee Mabiala-Maye
Advancing Maternal Health Equity In Nebraska: Examining Prenatal Care Access Disparities, Policy Context, And Doula Integration As A Complementary Solution, Marlette Grace Dulcinee Mabiala-Maye
Theses & Dissertations
Maternal health inequities persist across the United States, with Black, Native American, and immigrant-origin women facing disproportionate barriers to timely prenatal care. This dissertation examined access to prenatal care in Nebraska, a mixed rural and urban state with extensive maternity care deserts, through three interrelated aims. Aim 1 analyzed PRAMS data using survey-weighted regression with race-by-socioeconomic-status interactions to characterize disparities in the timing and barriers to care. Aim 2 evaluated the state’s October 2020 Medicaid expansion across pre-pandemic, acute pandemic, and post-expansion periods. Aim 3 applied qualitative description and the Consolidated Framework for Implementation Research to interviews withtwenty-three maternity care …
For Weight Loss: Why Do Glp-1 Agonists Work, And How Can We Make Them Work Better?, Charlise Giang, Jieyi Meng, Mahmoud Ali Mohammad, Zhenqi Liu, Xinle Wu, Yi Zhu
For Weight Loss: Why Do Glp-1 Agonists Work, And How Can We Make Them Work Better?, Charlise Giang, Jieyi Meng, Mahmoud Ali Mohammad, Zhenqi Liu, Xinle Wu, Yi Zhu
Children’s Nutrition Research Center Staff Publications
Glucagon-like peptide 1 receptor agonists (GLP-1RAs) have revolutionized the management of not only type 2 diabetes but also obesity. However, even with rapid therapeutic advances in GLP-1RAs, questions regarding the fundamental principles of GLP-1-mediated weight loss and the enhanced efficacy of next-generation therapies remain. In this comprehensive review article, we first examine the milestones of GLP-1, from its initial discovery and biological characterization to its successful translation into clinical therapy. Furthermore, this review highlights the latest clinical trial data, specifically HbA1c reduction, weight-loss efficacy, and safety profiles, while exploring current pipelines of major pharmaceutical companies. Additionally, we delineate the mechanistic …
Church Tape Collection, Approximately 1969-2008, Ministers
Church Tape Collection, Approximately 1969-2008, Ministers
Center for Restoration Studies Archives, Manuscripts and Personal Papers Finding Aids
No abstract provided.
Imsa Summer Symposium 2026, Student Inquiry And Research(Sir)
Imsa Summer Symposium 2026, Student Inquiry And Research(Sir)
IMSAloquium Event Booklets
For nearly four decades, IMSA has worked to advance the human condition through educational innovation. The Summer Symposium is our annual showcase for the research projects that were conducted in IMSA’s experiential learning programs between May and August. These programs include Student Inquiry and Research (SIR), IN2 Business Internships, and the Student Research and Experiential Learning Opportunity (SRELO) program. For the first time, we are also excited to welcome IMSA Research, Inquiry Skills, and Experimentation (RISE) students to present at the Summer Symposium.
Fort Hays State University Tiger Weekly, August 14, 2026, University Relations
Fort Hays State University Tiger Weekly, August 14, 2026, University Relations
Tiger Weekly Newsletters
No abstract provided.
Mechanical Characterization Of Stereolithography 3d Printing Resins Using Tensile And Flexural Testing, Oliver Stitt
Mechanical Characterization Of Stereolithography 3d Printing Resins Using Tensile And Flexural Testing, Oliver Stitt
Mechanical Engineering and Materials Science Independent Study
This study characterized and compared Clear V5 and Tough 1500 Resin V2 specimens printed on a Formlabs Form 4 SLA resin printer using tensile and flexural mechanical testing. Tensile testing was based on ASTM D638-14 using Type IV specimen geometry, and flexural testing was based on ASTM D790-17 using three-point bending geometry. Clear V5 produced a mean tensile modulus of 1953.5 MPa and flexural modulus of 1479.1 MPa, compared with 1328.0 MPa and 1103.9 MPa for Tough 1500. Clear V5 also reached the higher maximum engineering stress in tension, while Tough 1500 showed a more compliant response. The results were …
Interpreting Title Vi: Translation Theory And The Making Of Language Policy, Olivia A. Allred
Interpreting Title Vi: Translation Theory And The Making Of Language Policy, Olivia A. Allred
Undergraduate Honors Theses
Title VI of the Civil Rights Act provides the primary statutory basis for the development of policies supporting language access. Rather than explicitly requiring institutions to accommodate individuals with limited English proficiency (LEP), the statute establishes a broad prohibition against discrimination based on race, color, and national origin. This thesis examines the process through which that broad statutory mandate has been interpreted and applied to specific language-access policies.
To elucidate the application of language access polices at the federal level, this analysis focuses on three landmark Supreme Court decisions concerning Title VI: Lau v. Nichols, Regents of the University …
Helal V. Mclawrence
All Decisions
Tenant moved to extend the time to vacate an unregulated apartment after failing to locate alternative housing despite holding a CityFHEPS voucher. The court denied the motion, holding that RPAPL § 753 and CPLR § 2201 do not authorize further delay where the parties—each represented by counsel—entered into a clear, final stipulation of settlement after full litigation, and that courts must enforce such stipulations with rigor.
3338 Fish Ave Llc V. Malcolm
All Decisions
Tenant, who had been self-represented when she stipulated to a final judgment of possession, moved to vacate the stipulation on the ground that she unknowingly waived a complete defense—landlord's failure to plead the applicability of the Good Cause Eviction Law as required for proceedings filed after April 20, 2024. The court granted the motion, finding the stipulation was entered into inadvisedly, and vacated both the stipulation and the judgment and warrant of eviction.
Pushed To The Edges? Electivity Patterns Of Urban Stream Homeless Encampments In Environmentally Burdened Areas, Serena Alexander, Bennett Williamson, Jeff Wootton, Costanza Rampini, Gregory Brian Pasternack, Yufang Jin, Rune Storesund, Igor Lacan
Pushed To The Edges? Electivity Patterns Of Urban Stream Homeless Encampments In Environmentally Burdened Areas, Serena Alexander, Bennett Williamson, Jeff Wootton, Costanza Rampini, Gregory Brian Pasternack, Yufang Jin, Rune Storesund, Igor Lacan
Faculty Research, Scholarly, and Creative Activity
Urban stream corridors in the San Francisco Bay Area have increasingly become locations for homeless encampments, yet little is known about the environmental conditions of these spaces. This study uses a geospatial electivity index to examine whether urban stream encampments in Santa Clara and Contra Costa counties are disproportionately located in census tracts with high pollution burdens, as measured by CalEnviroScreen 4.0. Findings show a statistically significant overrepresentation of encampments in census tracts in the top 25% of pollution and vulnerability scores, and a significant underrepresentation in lower-pollution areas. These results suggest that homeless individuals are being pushed toward environmentally …
The Efficacy Of Transversus Abdominis Plane Block As An Adjunct To Spinal Anesthesia For Cesarean Delivery: An Evidence Synthesis And Implementation Toolkit, Alyssa Hebert, Alex Potts, Gabriela Robertson
The Efficacy Of Transversus Abdominis Plane Block As An Adjunct To Spinal Anesthesia For Cesarean Delivery: An Evidence Synthesis And Implementation Toolkit, Alyssa Hebert, Alex Potts, Gabriela Robertson
Graduate Theses, Dissertations, and Capstones
Postoperative pain hinders cesarean delivery recovery and overall patient experience. Although spinal anesthesia with intrathecal opioids remains the standard of practice, associated side effects and concerns regarding opioid exposure highlight the need for effective opioid-sparing strategies. Anesthesia providers play a critical role in advancing postoperative pain management through evidence-based protocol development, provider education, and interdisciplinary collaboration to optimize maternal outcomes. The transversus abdominis plane (TAP) block provides somatic analgesia to the anterior abdominal wall by targeting the thoracolumbar nerves (T6–L1) and has increasingly been incorporated into multimodal postoperative pain management strategies for abdominal surgery. Nevertheless, a gap remains in obstetric …
Rickettsia Africae Discovered In A Short-Term Urban Traveller To South Africa: A Case Report, Zunairah Sikder
Rickettsia Africae Discovered In A Short-Term Urban Traveller To South Africa: A Case Report, Zunairah Sikder
Binghamton University Undergraduate Journal
Rickettsia Africae is a pathogen that causes African tick-bite fever (ATBF). Transmission typically occurs from ticks within the Central and South African regions. Previous studies suggested that ATBF is not uncommon amongst travelers to rural sub-Saharan Africa, especially during the rainy months of November through April. However, this case report highlights a woman who contracted ATBF in novel conditions. The 70-year-old woman reported travelling strictly to and from the local church and hotel for her four-day stay in July. After returning to America, the patient experienced extreme irritation on her arm, as well as complaints of headaches. She presented to …
A Message From The Managing Editor, Carissa Bayack
A Message From The Managing Editor, Carissa Bayack
Binghamton University Undergraduate Journal
A message from the 2025-2026 Managing Editor of the Binghamton University Undergraduate Journal, Carissa Bayack.