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Bi-5756 Reduces Graft-Versus-Host Disease Through Cb1-Mediated Treg Upregulation, Sena Kim, Abdul-Jalil Dania, Sora Lim, Jaebok Choi Aug 2025

Bi-5756 Reduces Graft-Versus-Host Disease Through Cb1-Mediated Treg Upregulation, Sena Kim, Abdul-Jalil Dania, Sora Lim, Jaebok Choi

2020-Current year OA Pubs

Cannabinoid receptor 1 (CB1) has been implicated in multiple inflammatory diseases by regulating pro-inflammatory mediators or altering immune cell polarization. However, the expression and direct functional role of CB1 in T cells remain largely unexplored. Here, we demonstrate that primary murine T cells express CB1 and that its novel agonist, BI-5756, directly increases the frequencies of regulatory T cells (Tregs) in primary murine pan T cells after activation. In addition, BI-5756 exhibits an in vivo protective effect against graft-versus-host disease (GvHD), an allogeneic T cell-mediated inflammatory complication after allogeneic hematopoietic cell transplantation (allo-HCT), resulting in an improved overall survival with …


Southtalks Focus On 'Reading The South', Rebecca Lauck Cleary Aug 2025

Southtalks Focus On 'Reading The South', Rebecca Lauck Cleary

University of Mississippi News

OXFORD, Miss. – The Center for the Study of Southern Culture focuses its programming for the University of Mississippi's 2025-26 academic year on the idea of "Reading the South." The center's SouthTalks events begin next week and support the theme.


Timely Resection Of Juvenile Nasopharyngeal Angiofibroma Following Embolization For Uncontrolled Acute Epistaxis Case Report., Koffi L. Lakpa, Timothy Mcculloch, Michael D. Puricelli Aug 2025

Timely Resection Of Juvenile Nasopharyngeal Angiofibroma Following Embolization For Uncontrolled Acute Epistaxis Case Report., Koffi L. Lakpa, Timothy Mcculloch, Michael D. Puricelli

Manuscripts, Articles, Book Chapters and Other Papers

Uncontrolled epistaxis in patients with juvenile nasopharyngeal angiofibroma requires prompt intervention. When embolization is required, neovascularization can occur, making expedited surgical resection essential. We conducted a single-institution, retrospective review of one patient. This case study details the patient's clinical presentation and his preoperative, intraoperative, and postoperative course. We present the management of a 14-year-old male with a juvenile nasopharyngeal angiofibroma, who 3 days after initial evaluation at our institution, developed uncontrolled epistaxis requiring embolization at an outside hospital before transfer back to our institution for further management. He initially presented to an outside emergency department with acute epistaxis refractory to …


Mycoplasma Pneumoniae-Induced Mucositis Sine Rash: Case Report In An Adult Patient, Mónica Gómez-Manzanares, Víctor Haro Gónzalez-Vico, Marina Montero-García, Omar Al-Wattar Ceballos Aug 2025

Mycoplasma Pneumoniae-Induced Mucositis Sine Rash: Case Report In An Adult Patient, Mónica Gómez-Manzanares, Víctor Haro Gónzalez-Vico, Marina Montero-García, Omar Al-Wattar Ceballos

Sultan Qaboos University Medical Journal

No abstract provided.


August 28, 2025, James Madison University Aug 2025

August 28, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.


Understanding The Why: Patient, Parent, And Oncologist Perspectives On Prognostic Communication Preferences In Advanced Childhood Cancer, Erin Batchelor, Rachel A Kentor, Calliope Reeves, Harmony Farner, Shoshana Mehler, Caroline Christianson, Erica C Kaye Aug 2025

Understanding The Why: Patient, Parent, And Oncologist Perspectives On Prognostic Communication Preferences In Advanced Childhood Cancer, Erin Batchelor, Rachel A Kentor, Calliope Reeves, Harmony Farner, Shoshana Mehler, Caroline Christianson, Erica C Kaye

Faculty, Staff and Students Publications

Background/objectives: High-quality prognostic communication in pediatric oncology is essential to support informed decision making, foster trust, and honor goals of care. While families differ in their preferences for how prognosis is discussed, clinicians often rely on assumptions rather than directly eliciting these preferences, risking misalignment and distress. To address this gap, we aimed to characterize patient, parent, and oncologist perspectives on key variables, experiences, and circumstances that influence their preferences for prognostic communication.

Methods: Semi-structured interviews were conducted with 85 participants (25 patients aged 12-25, 40 parents, and 20 oncologists) to elicit their preferences for prognostic communication and the reasons …


Hiv-1 Controllers Possess A Unique Cd8+ T Cell Activation Phenotype And Loss Of Control Is Associated With Increased Expression Of Exhaustion Markers, Amber D. Jones, Zachary Capriotti, Erin Santos, Angel Lin, Rachel Van Duyne, Stephen Smith, Zachary Klase Aug 2025

Hiv-1 Controllers Possess A Unique Cd8+ T Cell Activation Phenotype And Loss Of Control Is Associated With Increased Expression Of Exhaustion Markers, Amber D. Jones, Zachary Capriotti, Erin Santos, Angel Lin, Rachel Van Duyne, Stephen Smith, Zachary Klase

Kimmel Cancer Center Papers, Presentations, and Grand Rounds

BACKGROUND: HIV-1 controllers are a rare population of individuals that exhibit spontaneous control of HIV-1 infection without antiretroviral therapy. Understanding the mechanisms by which HIV-1 controllers maintain and eventually lose this ability would be highly valuable in HIV-1 cure or vaccine research. Previous work revealed the ability of CD8+ T cells isolated from HIV-1 controllers to suppress HIV-1 replication in matched CD4+ T cells and PBMCs ex vivo and suggested the loss of control may be tied to CD8+ T cell exhaustion.

RESULTS: We explored whether CD8+ T cell exhaustion plays a role in the maintenance and loss of control …


Professor Richard Compton, Editorial Advisory Board Member, And Professor Bin Ren, Editorial Board Member Of Journal Of Electrochemistry, Have Been Awarded The 2025 Prizes Of The International Society Of Electrochemistry (Ise), Editorial Office Of J.Electrochem. Aug 2025

Professor Richard Compton, Editorial Advisory Board Member, And Professor Bin Ren, Editorial Board Member Of Journal Of Electrochemistry, Have Been Awarded The 2025 Prizes Of The International Society Of Electrochemistry (Ise), Editorial Office Of J.Electrochem.

Journal of Electrochemistry

No abstract provided.


Second Announcement Of The 23Rd National Congress On Electrochemistry In 2025, Chinese Society Of Electrochemistry (Cse) Aug 2025

Second Announcement Of The 23Rd National Congress On Electrochemistry In 2025, Chinese Society Of Electrochemistry (Cse)

Journal of Electrochemistry

No abstract provided.


The George-Anne Daily, Georgia Southern University Aug 2025

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.


Faculty Senate Minutes, Academic Year 2024-2025, August 28, 2025, Faculty Senate Aug 2025

Faculty Senate Minutes, Academic Year 2024-2025, August 28, 2025, Faculty Senate

Faculty Senate Minutes

Minutes for the Faculty Senate Meeting held August 28, 2025.


Ole Miss Student Combines Passions In Italian Medical Fellowship, Marisa C. Atkinson Aug 2025

Ole Miss Student Combines Passions In Italian Medical Fellowship, Marisa C. Atkinson

University of Mississippi News

OXFORD, Miss. – Sparked by a love of travel and aspirations of becoming a doctor, University of Mississippi junior Samantha Ragan experienced the best of both worlds when she spent time in Italy this summer as part of a global health fellowship program.


Law School News: Remembering Bruce I. Kogan (Nov 1944-Aug 2025) : Founding Faculty, Beloved Teacher, And Lifelong Champion Of Rwu Law 08-28-2025, Helga Melgar Aug 2025

Law School News: Remembering Bruce I. Kogan (Nov 1944-Aug 2025) : Founding Faculty, Beloved Teacher, And Lifelong Champion Of Rwu Law 08-28-2025, Helga Melgar

Life of the Law School (1993- )

No abstract provided.


Vanja Y. Watkins, Myrna J. Layton Aug 2025

Vanja Y. Watkins, Myrna J. Layton

Faculty Publications

Vanja Louise Yorgason was born on September 22, 1938 in Ogden, Utah, the daughter of R. Milton and Norma Johns Yorgason. Vanja grew up in a musical home. Her father was a violinist, and her mother a pianist and an organist. Vanja and her four brothers learned to “sing four-part hymns in tune unaccompanied.”1 Their parents felt that music was an important part of their children’s education, and made the necessary sacrifices to provide music lessons.


Dairy And Food Science Student Newsletter, August 28, 2025, Department Of Dairy And Food Science Aug 2025

Dairy And Food Science Student Newsletter, August 28, 2025, Department Of Dairy And Food Science

Dairy and Food Science Student Newsletter

No abstract provided.


Minutes, Crummer Graduate School Faculty Meeting, Thursday, August 28, 2025, Crummer Graduate School Of Business Faculty Aug 2025

Minutes, Crummer Graduate School Faculty Meeting, Thursday, August 28, 2025, Crummer Graduate School Of Business Faculty

Crummer Graduate School of Business Minutes and Reports

No abstract provided.


Low Head Dam Fatalities Data 1900 To August 2025, Rollin H. Hotchkiss, Edward William Kern, John Guymon, Paige A. Gordichuk Aug 2025

Low Head Dam Fatalities Data 1900 To August 2025, Rollin H. Hotchkiss, Edward William Kern, John Guymon, Paige A. Gordichuk

ScholarsArchive Data

This dataset documents fatalities at low head dams in the United States between 1900 and August 2025. The records were compiled between 2012 and 2025 by research assistants at Brigham Young University under the direction of Dr. Rollin Hotchkiss. Data were incorporated into the database from Dr. Bruce Tschantz, Charlie Walbridge of the American Whitewater Association, public submissions through a “Report an Incident” form, and publicly available sources, including newspaper archives and public records. Originally stored in a MySQL database and later transferred to Google Sheets, the August 2025 version was exported to Excel. The purpose of the dataset is …


Book Review - Claiming The Courageous Middle: Daring To Live And Work Together For A More Hopeful Future, Sunshine Sullivan Aug 2025

Book Review - Claiming The Courageous Middle: Daring To Live And Work Together For A More Hopeful Future, Sunshine Sullivan

International Christian Community of Teacher Educators Journal

A review of Mullen, S.A. (2004). Claiming the courageous middle: Daring to live and work together for a more hopeful future. Baker Academic. (ISBN: 9781493444526, 200 pgs., soft cover)


State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education Aug 2025

State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education

California

No abstract provided.


The Effect Of Group Counseling On Hope With Diverse Undergraduates During Sustainability-Focused Internship, Hailey Spinks, Michael D. Hannon, Matthew Murray, Nina M. Goodey, Lora Billings, Amy Tuininga Aug 2025

The Effect Of Group Counseling On Hope With Diverse Undergraduates During Sustainability-Focused Internship, Hailey Spinks, Michael D. Hannon, Matthew Murray, Nina M. Goodey, Lora Billings, Amy Tuininga

PSEG Institute for Sustainability Studies Publications

Many adolescents report feeling overwhelmed, depressed, anxious, and hopeless in the face of global climate change. These feelings are both valid and antithetical to the necessary hope and courage it takes to address real-world environmental crises and contribute to meaningful societal impact. The Green Teams Program, an internship-based experiential learning initiative, prepares young professionals with skills and knowledge needed to address these challenges and provides an intentionally inclusive and safe environment for students from all backgrounds to do so. This structured environment includes psychoeducational group counseling among other supports. Intern self-assessments revealed significant gains in measures of Hope, Agency, …


Geol 64: Planetary Geology - Syllabus, Dara Laczniak Aug 2025

Geol 64: Planetary Geology - Syllabus, Dara Laczniak

Open Educational Resources

This Open Educational Resources (OER) syllabus is for an introductory planetary geology course that utilizes results from space missions to expose students to the surface features, composition, geological activity, and probable history of the planets, moons, asteroids, and comets of the solar system. It also places space exploration into the context of larger societal issues such as global warming and natural resource availability and addresses topics such as the ethics of space exploration and hazards of space travel. This OER syllabus aims to foster student-centered learning, critical thinking, data analysis and communication skills, and creativity. Assigned readings are compiled into …


Computational Detection Of Articulation Transients In Clarinet Performance, Whitney L. Coyle, Max Griffin, Makayle S. Kellison Aug 2025

Computational Detection Of Articulation Transients In Clarinet Performance, Whitney L. Coyle, Max Griffin, Makayle S. Kellison

Faculty Publications

Accurate measurement of note-to-note transitions is essential for analyzing articulation in clarinet performance. Traditional methods rely on either subjective amplitude thresholds—such as the time between 5% and 95% RMS levels—or direct measurement of tongue-reed contact time using reed-mounted sensors. These approaches are limited by their dependence on user-defined parameters or invasive hardware. This study proposes a computational alternative: ΔT, a curvature-based metric defined as the time interval between surrounding minima in the second derivative of the mouthpiece pressure envelope. Using data from a sensor-equipped mouthpiece (SEM), we compare ΔT to both threshold-based timing (Tt) …


Adult-Child Caregivers’ Fear And Coping Regarding The Risk Of Inheriting Alzheimer’S Disease, Rebecca Anne Ledbetter Aug 2025

Adult-Child Caregivers’ Fear And Coping Regarding The Risk Of Inheriting Alzheimer’S Disease, Rebecca Anne Ledbetter

Walden Dissertations and Doctoral Studies

Caring for elderly parents with Alzheimer’s disease (AD) poses two major challenges for adult-child caregivers: the tasks involved in taking care of ailing parents and also potentially living in fear of developing the same disease. This research examined how caregivers with such fear regard their vulnerability to AD and how they manage the stress that comes with caregiving for someone with a disease they dread developing themselves. This grounded theory study employed the appraisal theory of emotions and the theory of moods as frameworks and aimed to establish awareness regarding coping strategies that adult-child caregivers have about caretaking and their …


Staff Education On Perinatal Opioid Use Disorder, Mukisha Livingston Gunter Aug 2025

Staff Education On Perinatal Opioid Use Disorder, Mukisha Livingston Gunter

Walden Dissertations and Doctoral Studies

Perinatal Opioid Use Disorder (POUD) constitutes a significant public health issue with important ramifications for both mothers and their newborns. The gap in practice identified for this Doctor of Nursing Practice staff education project was the perinatal nurses’ lack of knowledge regarding POUD. The problem was the need for POUD education for the nurses. The practice focus questions were: Will there be a change in knowledge by perinatal nurses following the delivery of the education as shown by a pretest/posttest? Will the participants evaluate the education as having met the program objectives related to the curriculum presented? Guided by the …


Staff Education To Use The Patient Health Questionnaire-9 To Improve Identification Of Depression Among Mental Health Clients, Lukresia Bhwanshe Kawira Aug 2025

Staff Education To Use The Patient Health Questionnaire-9 To Improve Identification Of Depression Among Mental Health Clients, Lukresia Bhwanshe Kawira

Walden Dissertations and Doctoral Studies

This doctoral project was an educational intervention to improve depression screening in a health clinic through standardized training using the Patient Health Questionnaire-9 (PHQ-9). The targeted practice issue was the variable use of the PHQ-9 which led to possible misdiagnosis or underdiagnosis of depression, a critically vital issue in nursing practice owing to the necessity of frontline mental status evaluation by nursing staff. The practice focused question was, for staff in a mental health clinic, will training on the use of the PHQ-9 tool increase knowledge toward the goal of improving the identification of depression among clients? Hence, the overall …


Social Media Vetting Governance And The Impact On Hiring Capacity, Jimmy Lampkin Aug 2025

Social Media Vetting Governance And The Impact On Hiring Capacity, Jimmy Lampkin

Walden Dissertations and Doctoral Studies

Human resource managers are concerned with weak social media vetting governance, as it is the number one predictor of reduced organizational capacity to hire candidates. Grounded in Lewin’s Situational Strength Theory, the purpose of this quantitative correlational project was to examine the relationship between social media vetting governance and organizational capacity to hire. The participants were 500 human resource leaders and hiring managers from organizations in the southwestern United States who completed the Job-Related Situational Strength Questionnaire and the Decision to Hire Scale. Although a priori power analysis required a minimum of 103 participants to detect a medium effect size, …


Library Publishing Research Agenda (2nd Ed.), Talea Anderson, Karen Bjork, Leigh-Ann Butler, Nina Collins, Perry Collins, Matthew Goldberg, Jonathan Grunert, Matthew Hunter, Michelle Lalonde, John Martin, Shawn Martin, John David Morgenstern, Talia Perry, Christopher Popovich, Liz Scarpelli, Janet Swatscheno, Willa Tavernier, Dan Tracy, Michelle Wilson, Mai Yamamoto Aug 2025

Library Publishing Research Agenda (2nd Ed.), Talea Anderson, Karen Bjork, Leigh-Ann Butler, Nina Collins, Perry Collins, Matthew Goldberg, Jonathan Grunert, Matthew Hunter, Michelle Lalonde, John Martin, Shawn Martin, John David Morgenstern, Talia Perry, Christopher Popovich, Liz Scarpelli, Janet Swatscheno, Willa Tavernier, Dan Tracy, Michelle Wilson, Mai Yamamoto

LPC Publications

This second edition of the Library Publishing Research Agenda builds on the foundation laid by the original 2020 publication, continuing to explore critical areas where research is needed to inform and strengthen practice in the field of library publishing. It offers updated and expanded exploratory overviews of six key topics (assessment, labor, accessibility, non-traditional research outputs, peer review, and partnerships), each including a contextual summary, refreshed or newly proposed research questions, and updated resources for further reading. This edition reflects new developments in the field and ongoing conversations within the community. It is intended to support current and future researchers, …


2025 August 28 - From My Notepads Newsletter, Brian E. Noland, Office Of The President, East Tennessee State University Aug 2025

2025 August 28 - From My Notepads Newsletter, Brian E. Noland, Office Of The President, East Tennessee State University

From My Notepads: A Newsletter from President Brian Noland

No abstract provided.


The Changing Dynamics Of India-China Relations Since 2014 : A Shift From Asymmetric To Symmetric Security Dilemma?, Soumyodeep Deb Aug 2025

The Changing Dynamics Of India-China Relations Since 2014 : A Shift From Asymmetric To Symmetric Security Dilemma?, Soumyodeep Deb

Lingnan Theses (MPhil & PhD)

The new global geopolitical order has shifted from the Atlantic to the Indo-Pacific at the dawn of the twenty-first century. Given the fact that both China and India are currently regarded as major rising powers, the relationship between the two countries is among the most important concerns in the contemporary geopolitical landscape. Therefore, it is of utmost significance to have a comprehensive understanding of the dynamics of their relationship. The dynamics of the relationship between China and India have been marked by the presence of a security issue for a considerable amount of time. It has been suggested that the …


Riverbay Corp. V. Dawson Aug 2025

Riverbay Corp. V. Dawson

All Decisions

In this nonpayment case, the tenant's attorneys made an oral motion for a civil penalty under CPLR § 5020(c) against the landlord for failing to file a satisfaction of judgment within 20 days after receiving full payment. The court dismissed the application, holding that Housing Court, a special proceeding, lacks jurisdiction to hear this claim. The court reasoned that CPLR § 5020(c) specifies that such a penalty is "recoverable by the judgment debtor" in a separate plenary action, not within the confines of a summary proceeding. The tenant was directed to pursue the claim in a different venue, such as …