Digital Commons Network^™

Experiences Of Managing And Living With Autoimmune Addison’S Disease In The Younger And Newly Diagnosed Adults: An Interpretative Phenomenological Analysis, Mathew Horodner

Walden Dissertations and Doctoral Studies

There is a lack of knowledge regarding the experiences of managing and living with autoimmune Addison’s disease (AD) in the younger and newly diagnosed adults. AD research usually focuses on biological or medication studies. Thus, the purpose of this qualitative study was to understand the lived experiences of the younger and newly diagnosed adults living with autoimmune AD. Consisting of the complex integration of biological, psychological, and social factors, Engel’s biopsychosocial model served as the study’s conceptual framework. I conducted this study to include the experiences of managing and living with autoimmune AD in the younger (18–35) and newly diagnosed …

8-Page Zine Extra Credit Assignment, Ricaute Rogers

Open Educational Resources

This is an 8-page minizine extra credit assignment that put into practice the concepts learned in CIS100.

Factors Associated With Falls Among Nursing Home Residents, Dorsenia Hendrix

Walden Dissertations and Doctoral Studies

Falls in nursing home facilities are prevalent, and numbers continue to rise as residents grow older and antipsychotic (AP) medications are prescribed more frequently. The purpose of this quantitative study was to investigate whether frequency of falls was related to the use of AP medications. Data (N=100) were collected from 2020 incident reports, investigation sheets, and patient charts generated by the State Department of Public Health regarding resident falls and the use of AP medications in a nursing home Facility located in the Southern United States. Social Cognitive Theory (SCT) was used to understand specific behavior patterns such as personal, …

Staff Education On Colorectal Cancer Screening To Improve Knowledge And Usage, Mary Tessie Thullah Bangura

Walden Dissertations and Doctoral Studies

Executive Summary: Staff Education Project Staff Education on Colorectal Cancer Screening to Improve Knowledge and Usage

Staff Education Project: Staff Education To Improve Nurses’ Knowledge, Self-Efficacy, And Motivation In Supporting Medication Adherence, Giovanna Happy

Walden Dissertations and Doctoral Studies

Medication nonadherence among individuals with psychiatric disorders remains a significant barrier to recovery, ranging from 40% to 60%. Contributing factors include fear of side effects, stigma, cognitive limitations, and complex regimens. This staff education project addressed challenges through the implementation of a structured, evidence-based intervention to improve adherence-supportive practices among 14 outpatient psychiatric nurses. A preimplementation needs assessment revealed inconsistent application of adherence strategies and low staff confidence. The project’s objective was to evaluate whether a structured education program could improve nurses’ knowledge by 15%, confidence by 15%, and willingness by 3.5 points on a Likert scale to promote medication …

Big Five Personality Traits As Predictors Of Funeral Directors’ Job Satisfaction, Teresa Busick

Walden Dissertations and Doctoral Studies

By 2037, annual deaths in the United States are expected to exceed 3.6 million, over 1 million more than in 2015. At the same time, the funeral service industry faces a serious staffing problem, with about 50% of funeral directors leaving the profession within 2 years. These combined challenges highlight the need to understand what contributes to job satisfaction and helps to retain these workers in this essential field. This quantitative correlational study examined whether the Big Five personality traits predict job satisfaction among funeral directors. Thus, the Big Five model of personality traits was used to guide the study. …

Strategies Used By Public Relations And Communications Executives To Implement Ethical Use Standards For Ai, Karl Bateson

Walden Dissertations and Doctoral Studies

Public relations and communications (PR&C) executives’ ineffective artificial intelligence (AI) strategies to develop and apply ethical frameworks for AI implementation can negatively impact organizations’ brand reputation. Grounded in AI4People and stakeholder theory, the purpose of this qualitative pragmatic inquiry project was to identify and explore the effective AI strategies PR&C executives used to develop and apply ethical frameworks for AI implementation while maintaining their organizations’ brand reputations. The participants were six PR&C executives who used effective strategies to develop and apply ethical frameworks for AI implementation while maintaining their organization’s brand reputation. Data were collected using semistructured interviews, public websites, …

An Action Research Study On Ai Video Vs. Written Feedback: Enhancing Undergraduate Academic Writing And Critical Thinking, Sandra Baroudi, Nida Mubeen, Suha Karaki

All Works

This action research explores how AI-assisted feedback formats influence students’ academic writing and critical thinking, a gap particularly relevant in the digital learning landscape. This study involved 40 undergraduate Emirati students divided into two groups, receiving either AI-generated video or written feedback across three assignments. Using a quantitative design, data were gathered using standardized critical thinking and academic writing skills rubrics. Additionally, students completed post-surveys to capture their perceptions, engagement levels and use of AI tools in the learning process. Results showed written feedback significantly improvemed critical thinking (M = 2.80, SD = 0.75) compared to video feedback (M = …

Cortical Functional Organization In Early Childhood, Jiaxin Tu

Arts & Sciences Graduate Student Theses and Dissertations

The advent of connectivity-based methods, particularly those utilizing spontaneous BOLD signals, has significantly advanced brain mapping and deepened our understanding of the human brain's functional architecture. While prior research has explored functional organization in early childhood, most studies have focused on coarse, group-level distinctions aligned with adult literature, often within narrow age ranges. This dissertation extends these investigations by examining cortical functional organization in greater detail among healthy infants and toddlers aged 1 to 5 years. Chapter 1 employs spontaneous BOLD signals in sleeping infants and toddlers to derive a group-level functional organization at the resolution of areas and networks. …

Chaperone-Usher Pathway Pili Adhesin Conformations And Inhibitors In Urinary Tract Infections, Edward Lopatto

Arts & Sciences Graduate Student Theses and Dissertations

Antibiotic resistant bacteria are becoming increasingly difficult-to-treat resulting in increased morbidity and mortality, especially for common infections such as urinary tract infections (UTIs). Globally, UTIs afflict over 400 million people a year. Numerous different gram-negative and gram-positive bacterial species cause UTIs, including uropathogenic Escherichia coli (UPEC), Klebsiella pneumoniae, and Acinetobacter baumannii. Many of these bacterial species are listed as pathogens of urgent concern by the Center for Disease Control due to the dangerous rise and prevalence of antibiotic resistance necessitating development of new therapeutic measures. Bacteria utilize adhesin factors, such as chaperone-usher pathway (CUP) pili to gain a foothold in …

Vigorous Physical Activity As A Potential Environmental Risk Factor In Renal Medullary Carcinoma, Daniel D Shapiro, Sagar S Mukhida, Andrew W Hahn, Ayman Isahaku, Schyler M Turner, Jessica P Cheng, Pankaj K Chauhan, Susan S Thomas, Beei Chan, Zita D Lim, Nizar M Tannir, Maria Chang Swartz, Pavlos Msaouel

Faculty, Staff and Student Publications

Purpose: Renal medullary carcinoma (RMC) is a rare but aggressive kidney cancer affecting young individuals with sickle hemoglobinopathies. Prior retrospective case-control and mouse modeling studies suggest a mechanism linking vigorous intensity physical activity to increased RMC risk in individuals with sickle hemoglobinopathies. This study aimed to prospectively investigate the association between vigorous intensity exercise and RMC.

Materials and methods: This study used a validated questionnaire to prospectively assess reported physical activity in a large cohort of patients with RMC compared to the activity of individuals without RMC. Between 2022 and 2024, patients with RMC (N = 39) were prospectively surveyed …

Pan-Cancer Immune And Stromal Deconvolution Predicts Clinical Outcomes And Mutation Profiles, Bhavneet Bhinder, Verena Friedl, Sunantha Sethuraman, Davide Risso, Kami E Chiotti, R Jay Mashl, Kyle P Ellrott, Jordan A Lee, Christopher K Wong, Kofi Gyan, Aditya Deshpande, Marcin Imielinski, Rohan Bareja, Josh Stuart, Myron Peto, Katherine A Hoadley, Alexander J Lazar, Andrew D Cherniack, Jingchun Zhu, Shaolong Cao, Mark Rubin, Wenyi Wang, Oliver F Bathe, Nicolas Robine, Li Ding, Peter W Laird, Wanding Zhou, Hui Shen, Vésteinn Thorsson, Jen Jen Yeh, Matthew H Bailey, Daniel Cui Zhou, Xianlu L Peng, Mary Goldman, Yongsheng Li, Anil Korkut, Nidhi Sahni, D Neil Hayes, Michael K A Mensah, Ina Felau, Anab Kemal, Samantha Caesar-Johnson, John A Demchok, Liming Yang, Martin L Ferguson, Roy Tarnuzzer, Zhining Wang, Jean C Zenklusen, Paul Spellman, Olivier Elemento

Faculty, Staff and Student Publications

Traditional gene expression deconvolution methods assess a limited number of cell types, therefore do not capture the full complexity of the tumor microenvironment (TME). Here, we integrate nine deconvolution tools to assess 79 TME cell types in 10,592 tumors across 33 different cancer types, creating the most comprehensive analysis of the TME. In total, we found 41 patterns of immune infiltration and stroma profiles, identifying heterogeneous yet unique TME portraits for each cancer and several new findings. Our findings indicate that leukocytes play a major role in distinguishing various tumor types, and that a shared immune-rich TME cluster predicts better …

Supporting Patients With Advanced Cancer And Their Spouses In Parenting Minor Children: Results Of A Randomized Controlled Trial, Kathrin Milbury, Sujin Ann-Yi, Meagan S Whisenant, Morgan Jones, Yisheng Li, Victoria Necroto, Sania D Yousuf, Mariana Chavez-Macgregor, Larrisa Meyers, Eduardo Bruera

Faculty, Staff and Student Publications

Introduction: Patients with advanced cancer and their spousal caregivers who parent minor children report unmet parenting concerns and increased psychological distress. Seeking to address these important supportive care needs, this RCT examined the feasibility, acceptability, and initial evidence for the efficacy of a novel psychosocial intervention.

Patients and methods: Patients with a metastatic solid malignancy and their spouses completed self-reported validated assessments of psychological symptoms and cancer-related parenting outcomes and were then randomized to the parent support intervention or a usual care (UC) group. Both groups were reassessed 6 and 12 weeks later. Dyads randomized to the counselor-led intervention attended …

Improving Genetics Equity: Identifying Women Eligible For Genetic Care Services Using Mammography Clinics In Underserved Areas As Screening Hubs, Darya Kizub, Rachel Bluebond, Sierra Green, Jessica Duckworth, Sreejesh Shanker, Autumn Vara, Banu Arun

Faculty, Staff and Student Publications

PURPOSE: Fewer than 20% of underserved individuals undergo guideline-concordant hereditary breast and ovarian cancer (HBOC) genetic testing (GT). Our study aimed to determine the proportion of women eligible for HBOC GT using a cancer genetics risk assessment (CGRA) tool at breast cancer (BC) screening clinics in underserved communities and to describe the program's impact.

METHODS: Participants were women who presented for BC screening at The Rose clinics, serving low-income underserved communities in southeast Texas, and completed the CGRA. High-risk individuals received bilingual educational materials and a saliva-based GT kit. Those with a pathogenic variant (PV) or a variant of uncertain …

Structural Brain Correlates Of Childhood Inhibited Temperament: An Enigma-Anxiety Mega-Analysis, Janna Marie Bas-Hoogendam, Rachel Bernstein, Brenda E. Benson, Samuel E. C. Frank, Kristin A. Buss, Koraly Pérez-Edgar, Giovanni A. Salum, Andrea P. Jackowski, Rodrigo A. Bressan, Anderson M. Winkler

Human Genetics Publications

Objective

Childhood inhibited temperament (cIT) is associated with an increased risk for developing internalizing psychopathology. Neurobiological characteristics identified by structural magnetic resonance imaging (MRI) may elucidate the neural substrates for cIT, but studies are scarce and often focus on particular regions of interest. Moreover, current findings lack replication. This preregistered analysis from the ENIGMA-Anxiety Working Group examined structural brain characteristics associated with cIT using a comprehensive whole-brain approach.

Method

Temperament assessments (behavioral observations, parent/teacher reports or self-reports on cIT before age 13 years) and MRI data (age at scan, 6-25 years) from international research sites (Europe, North America, South America) …

Vitamin D Receptor (Vdr) And Autoimmune Diseases, Zahraa M. Al-Taee, Noor Mahommoud Naji, Zeena Hadi Obaid Alwan, Anmar M. K. Al-Maamori, Rasha Kadhim Mahdi

Hilla University College Journal For Medical Science

The vitamin_D_receptor (VDR) has great role in the regulates of expression of gene in several organs, responsive to vitamin D, after activation by physiologically active vit.D. There is strong evidence that vit.D is work in several physiological pathways, since vit.D-activating receptors and enzymes have been found in cell types that are unrelated to mineral and bone homeostasis. Many processes are affected by the so-called non-classic effects of VDR activation. These involve cell death, growth and reproduction of cells, and immune cell activity among many others. Moreover, immunity cells such as activated “CD4+ and CD8+ T cells, B cells, neutrophils, and …

Effect Of Exclusive Bottle Feeding On Infant‘S Serum Calcium And Serum Vitamin D3 And Its Comparison With Other Types Of Feeding In Diyala Governorate, Iraq, Hailah Othman Habeeb, Saif Hakeem Tofiq, Haider Jwad Dawod

Hilla University College Journal For Medical Science

Background: The mixed feeding means that the infant gets bottle milk and breast milk. Bottle feeding serves as incomplete nutritional source for the first six months of infant’s life because bottle feeding not contains all essential nutrients that necessary for the physiological growth and development of infants.

Objectives: The aim of this research is to determine impact of breastfeeding feeding other than formula feeding,, or a mixed feeding ,on serum calcium and blood vitamin D3 levels in infants.

Materials and Methods: Fifty patients were enrolled in this study. We collected the sample from the infants and children (first 2 years …

Evaluation Of Triglyceride/High Density Lipoprotein Ratio As A Diagnostic And Prognostic Marker For Reduced Ejection Fraction Heart Failure In Comparison To Brain-Natriuretic Peptide, Safa Mohammed Hassan, Rawaa Hadi Shareef

Hilla University College Journal For Medical Science

Background: heart failure is a condition that heart cannot pump blood in efficient way and this result in building up fluid and a reduced supply of oxygen to organs. Also, it can result from conditions like heart disease, hypertension, or diabetes. Brain natriuretic peptide (BNP) can be used in the diagnosis and evaluation of heart failure severity. The triglycerides-to-HDL ratio is a key marker of cardiovascular risk in heart failure, reflecting insulin resistance and metabolic health. A high ratio is associated with worse outcomes, including increased inflammation and arterial stiffness.

Objectives: To evaluate the diagnostic and prognostic value of Triglyceride …

Pan-Cancer Immune And Stromal Deconvolution Predicts Clinical Outcomes And Mutation Profiles, Bhavneet Bhinder, Sunantha Sethuraman, R Jay Mashl, Li Ding, Matthew H Bailey, Daniel Cui Zhou, Et Al.

2020-Current year OA Pubs

Traditional gene expression deconvolution methods assess a limited number of cell types, therefore do not capture the full complexity of the tumor microenvironment (TME). Here, we integrate nine deconvolution tools to assess 79 TME cell types in 10,592 tumors across 33 different cancer types, creating the most comprehensive analysis of the TME. In total, we found 41 patterns of immune infiltration and stroma profiles, identifying heterogeneous yet unique TME portraits for each cancer and several new findings. Our findings indicate that leukocytes play a major role in distinguishing various tumor types, and that a shared immune-rich TME cluster predicts better …

Seasonal Sea Ice Characterized The Glacial Arctic-Atlantic Gateway Over The Past 750 000 Years, Monica Winsborrow, Pengyang Song, Simon Belt, Jochen Knies, Henning A. Bauch, Lukas Smik, Gerrit Lohmann

School of Geography, Earth and Environmental Sciences

The past occurrence of an extreme ~1-kilometer–thick Arctic Ocean–Nordic Seas ice shelf has been inferred from submarine landscape features and geochemical records, although fundamental aspects of its characteristics, impacts, and timing remain highly debated. Here, we challenge this pan-Arctic glaciation hypothesis by investigating two sites from the Arctic-Atlantic gateway (AAG) and the Nordic Seas. Suborbital to millennial-scale surface water bioproductivity changes provide no evidence for a continuous ice shelf in the AAG and the Nordic Seas over the past ~750,000 years. Instead, proxy data and model simulations reveal the persistent presence of seasonal sea ice cover and open water phytoplankton …

Book Review: River Fiction Of India: Intersectional Flows Of Narratives, Geographies, And Histories, Nilay Patel

Critical Humanities

Book Review of

River Fiction of India: Intersectional Flows of Narratives, Geographies, and Histories,

edited by Subhadeep Ray

London & New York: Routledge, 2025

306 pp.

ISBN: 978-1-032-66253-4 (hbk)

ISBN: 978-1-032-98346-2 (pbk)

ISBN 978-1-003-59818-3 (ebk)

An Interview With Anthony Viola, Anthony Viola, John Van Kirk

Critical Humanities

Anthony Viola interviewed by John Van Kirk

The Human Catalyst And Extractivist Fiction: A Close Reading Of Siddhartha Sarma’S Year Of The Weeds And Pundalik N Naik’S The Upheaval, Elwin Susan John Dr

Critical Humanities

Literary narratives have been abetting the various global faces of climate crisis, ever since the disciplines of humanities and social sciences have become vocal about the Anthropocene. The discussions have been mostly centered around the discourses of capitalism, imperialism, rights and subalterity. By reading some of these foundational grips on ecological crisis, the present essay analyses literary narratives on mining and extraction in India from the standpoint of a human catalyst; which is defined as an entity that can cause a chain reaction, that may or may not result in the annihilation of the initial catalyst. The essay will begin …

The Extraction Unconscious: Solar-Powered Utopias In Catching The Sun (2015) And In The Name Of Lithium (2021), Isidora Cortés-Monroy

Critical Humanities

By comparing the depictions of future energy regimes in the two ecodocumentaries, Catching the Sun (2015) and In the Name of Lithium (2021), this article explores representations of post-carbon futures from the US and Argentina. Read closely alongside Frederic Jameson’s notions of utopias, the article delineates the extent to which a solar powered future challenges and reiterates current neocolonial extractivist structures. Basing myself on Patricia Yaeger’s concept of an “energy unconscious,” I argue that these solar utopias maintain an “extraction unconscious” that continues to produce sacrifice zones where primary commodities needed for the energy transition can be found. By analysing …

Towards An Indigenous Climate Epistemology: Bringing The Newa Literary Tradition Of The Swasthani Vrata Katha In Conversation With The Festival Tradition Of The Macchindra Nath Jatra, Shangrila Joshi Dr.

Critical Humanities

This paper brings into conversation two Newa cultural traditions to articulate notions of climate adaptation, resilience, and mitigation, to illustrate how ways of knowing, ways of being, and ways of governing are inherently linked. These articulations offer a framework for developing what the author calls an Indigenous Climate Epistemology. The two cultural traditions reviewed include: a 17^th century Newa literary tradition that advocates for keeping oil in the ground, and that instructs ordinary people to engage in ritual acts seemingly designed to develop personal and community resilience; and a 1700 year old annual community festival designed to avert catastrophes …

On The Edge Of The Abyss: Cultural Responses To Extractivism In The Andes, Jack Martinez Arias

Critical Humanities

This work examines the contemporary cultural productions of Cerro de Pasco, a city in constant destruction due to an ever-expanding open pit mine that has grown to over a mile wide since the 1950s. Drawing on Latin American environmental humanities and discursive analysis, I conduct a close reading of poems, stories, performances, and audiovisual works by local artists responding to this largely overlooked apocalyptic scenario. By analyzing narrative strategies such as repetition and irony, I identify recurring themes and establish common concerns related to extractivism, urban extinction, illness, and death. This study seeks to understand how these cultural productions envision …

The Radical Potential Of Ecopoetics: Ecological Intimacy In Forrest Gander’S Twice Alive, Thomas Storey

Critical Humanities

Ecopoetics is a contested term, one defined by its capaciousness. Through its focus on deep ecology, it draws together the world system and the individual, the collective and the singular, and the global and the placed-based within its dialectical framework, without resolving any of these oppositions. Instead, the apparent contradictions underlying ecopoetics offer productive material for a poetic praxis that aims to foreground the complex connections that string together nature, culture, politics, and society. Forrest Gander’s Twice Alive engages with these contradictions in an attempt to foreground the intimacy of ecological thinking, and its basis in personal connections that are …

Introduction: Volume 3 Issue 2, Critical Humanities

Critical Humanities

An Introduction to Vol 3, Issue 2

Imposter Syndrome And Degree Completion Among Marginalized Graduate Students, Ryan A. Finner

2025 Symposium

Imposter Syndrome is a mindset that troubles many graduate students across various countries, degree programs, ethnicities, sexualities and genders. The term Imposter Syndrome refers to the feeling of being a fraud, despite achieving success and the persistent fear of being exposed as unqualified or undeserving. While this phenomenon affects many, it can appear much worse in marginalized populations, this is due to the lack of resources, support and representation of minorities in professional and higher education environments. This research focuses on marginalized graduate students and aims to figure out what key factors are leading to incomplete or delayed degree completion. …

Blood Flow Occlusion Superimposed On Low-Volume, Low-Intensity Knee Extensions Does Not Evoke Hypoalgesia: A Pilot Study, Sophie-Jayne Morgan, Jenny Zhang, Neil Lemay, Neda Khaledi, Saied J. Aboodarda

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 6: Issue 1, Article 9, 2025. Exercise-induced hypoalgesia (EIH) is a transient decrease in pain perception that can be observed following various tasks, including low-intensity and high-intensity exercise. The application of blood flow occlusion (BFO) can help enhance exercise adaptations while being able to exercise at a low intensity, which has important implications for clinical and rehabilitative settings. Through descending inhibitory pathways, BFO-induced pain can potentially alleviate exercise-induced pain. This study aimed to assess whether the superimposition of BFO – and its associated augmented perceived responses – during low-intensity, low-volume resistance exercise could …