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“Rj Is About Learning How To Be Together”: A Qualitative Study Of School-Based Restorative Justice And Pandemic Recovery, Annmary S. Abdou, Ashley M. Mayworm Jul 2025

“Rj Is About Learning How To Be Together”: A Qualitative Study Of School-Based Restorative Justice And Pandemic Recovery, Annmary S. Abdou, Ashley M. Mayworm

Education Faculty Articles and Research

The COVID-19 pandemic has profoundly impacted educational landscapes by disrupting instructional modalities, widening equity gaps, and accelerating the mental health needs of students and educators. This qualitative study explores the perspectives of school-based restorative justice (RJ) practitioners as they navigated challenges and opportunities during the pandemic and reflected on its potential role in recovery efforts. Through a participatory action research (PAR) process, survey data were collected from RJ practitioners and leaders across diverse educational settings to examine (1) the impact of the pandemic on RJ implementation, (2) the priorities of educators in pandemic recovery, and (3) the role RJ can …


First National Study On Genomic Profiling Of Escherichia Coli In United Arab Emirates (Uae) Aquatic Environments Shows Diverse Quinolone And Cephalosporin Resistance, A. Papadopoulou, C. A. Moubareck, D. Ryder, A. L. Powell, M. Stone, A. W. Joseph, M. A. Khan, E. Light, D. W. Verner-Jeffreys, J. H. Stahl, W. J.F. Le Quesne Jul 2025

First National Study On Genomic Profiling Of Escherichia Coli In United Arab Emirates (Uae) Aquatic Environments Shows Diverse Quinolone And Cephalosporin Resistance, A. Papadopoulou, C. A. Moubareck, D. Ryder, A. L. Powell, M. Stone, A. W. Joseph, M. A. Khan, E. Light, D. W. Verner-Jeffreys, J. H. Stahl, W. J.F. Le Quesne

All Works

Antimicrobial resistance (AMR) is a serious threat to human, animal and plant health, and over recent years the role of the aquatic environment as a hotspot and dissemination route for resistant bacteria has been increasingly recognised. The United Arab Emirates (UAE) has identified AMR as a critical area of concern; however, limited studies have been conducted regarding the presence of AMR in aquatic environments in the region. This study addresses this gap by conducting a national surveillance to better understand the prevalence of aquatic AMR. We investigated the phenotypic and genotypic resistances in Escherichia coli (E. coli) isolates (n= 256) …


A Series Of Successful Emergency Department Thoracotomies With Expeditious Recovery, Jessica A. Nicholson, Mahmoud K. Abd-El-Hafez, Andrew G. Nicholson, Tanya J.T. Starr, Celeste Murtha, Mark J. Lieser, John M. Chipko Jul 2025

A Series Of Successful Emergency Department Thoracotomies With Expeditious Recovery, Jessica A. Nicholson, Mahmoud K. Abd-El-Hafez, Andrew G. Nicholson, Tanya J.T. Starr, Celeste Murtha, Mark J. Lieser, John M. Chipko

Student Publications

Resuscitative thoracotomy is an invasive, morbid procedure indicated in the emergent management of blunt or penetrating trauma to the chest. It allows for rapid access to the thoracic cavity and treatment of the underlying pathology. Survival following traumatic cardiac injury relies on a near-impeccable combination of rapid assessment by properly trained emergency medical services personnel, rapid transport to a capable emergency center, accelerated access to the thoracic cavity within 10 min of cardiopulmonary resuscitation initiation, and excellent perioperative resuscitation. Overall survival rate following resuscitative thoracotomy in the United States is 9.6%. In addition, not all who survive make an acceptable …


Association Between Antioxidant Defense Systems And Celiac Disease, Saad Kadhim Taher Yahya Jul 2025

Association Between Antioxidant Defense Systems And Celiac Disease, Saad Kadhim Taher Yahya

Hilla University College Journal For Medical Science

Background: Intake of gluten activates the immune system in CD patients resulting in tissue damage to their digestive system.

Objectives: The oxidative stress status as well as antioxidant defense mechanisms in persons with CD and non-CD individuals while evaluating gluten-free dietary impact.

Methods: A total of 100 CD patients along with 100 healthy participants received inclusion for this study. The laboratory analysis determined oxidative stress through MDA, AOPP, and 8-OHdG examinations of bloodstream markers. The study measured antioxidant defenses using FRAP and TEAC techniques to examine SOD, CAT, GPx, and TAC. Tissue examination and blood tests were used to measure …


The Prevalence And Correlates Of Aberrant Opioid-Related Behaviours Among Patients With Sickle Cell Disease In Oman: A Cross-Sectional Study, Abdullah Al Abulsalam, Khawla Al Kindi, Abdullah Al Ghailani, Hamed Al Sinawi, Naser Al Balushi, Salam Al Kindi, Sathiya P. Murthi, Amal Al Fahdi, Mohammed Al Alawi Jul 2025

The Prevalence And Correlates Of Aberrant Opioid-Related Behaviours Among Patients With Sickle Cell Disease In Oman: A Cross-Sectional Study, Abdullah Al Abulsalam, Khawla Al Kindi, Abdullah Al Ghailani, Hamed Al Sinawi, Naser Al Balushi, Salam Al Kindi, Sathiya P. Murthi, Amal Al Fahdi, Mohammed Al Alawi

Sultan Qaboos University Medical Journal

Objectives: This study aimed to assess the prevalence of aberrant opioid-related behaviours (AORB) among patients with sickle cell disease (SCD) in Oman and identify associated risk factors. Methods: This cross-sectional analytical study was conducted at Sultan Qaboos University Hospital, Muscat, Oman from June to December 2022. Patients with SCD aging 18–65 years old were included and clinically observed for more than 3 months. The Current Opioid Misuse Measure (COMM) was used to evaluate AORB with scores of ≥9 indicating high risk. Demographic and clinical data were collected. The association between AORB and clinical-demographic variables was examined using the Chi-square test. …


Haljamar Realty Corp. V. Mizrachi Jul 2025

Haljamar Realty Corp. V. Mizrachi

All Decisions

In this nonpayment case, the court awarded the tenants a substantial rent abatement of over $76, 000 for the landlord's breach of the warranty of habitability. The tenants successfully proved the existence of numerous conditions, including leaks, mold, and defective surfaces, using HPD violations and trial testimony. While the landlord was granted a final money judgment for the remaining arrears, the court significantly reduced the amount owed. The decision underscores the importance of a fact-based defense in abatement cases to meet the preponderance of the evidence standard.


Development And Validation Of Risk Models For Hospital-Acquired Bleeding In Medical Inpatients: The Medical Inpatients Thrombosis And Hemostasis (Mith) Study, Neil A Zakai, Katherine Wilkinson, Andrew D Sparks, Ryan T Packer, Nicholas S Roetker, Allen B Repp, Mansour Gergi, Chris Holmes, Mary Cushman, Timothy B Plante, Hanny Al-Samkari, Allyson M Pishko, William A Wood, Camila Masias, Radhika Gangaraju, Ang Li, David Garcia, Kerri L Wiggins, Jordan K Schaefer, Nicholas L Smith, Augusto Ferraris, Karlyn A Martin, Deirdra R Terrell, Leslie A Mcclure Jul 2025

Development And Validation Of Risk Models For Hospital-Acquired Bleeding In Medical Inpatients: The Medical Inpatients Thrombosis And Hemostasis (Mith) Study, Neil A Zakai, Katherine Wilkinson, Andrew D Sparks, Ryan T Packer, Nicholas S Roetker, Allen B Repp, Mansour Gergi, Chris Holmes, Mary Cushman, Timothy B Plante, Hanny Al-Samkari, Allyson M Pishko, William A Wood, Camila Masias, Radhika Gangaraju, Ang Li, David Garcia, Kerri L Wiggins, Jordan K Schaefer, Nicholas L Smith, Augusto Ferraris, Karlyn A Martin, Deirdra R Terrell, Leslie A Mcclure

Faculty, Staff and Students Publications

Background: Hospital-acquired (HA) bleeding in medical inpatients is a serious complication with limited tools to predict risk.

Objectives: This study aimed to develop and validate risk assessment models (RAMs) for anatomic location-specific HA bleeding in medical inpatients using objective and routinely available risk factors.

Methods: Patients aged ≥18 years admitted to medical hospital services from 6 health systems and 15 hospitals in the United States between 2016 and 2020 for at least 1 midnight and without bleeding at admission were eligible for inclusion. Two health systems (10 hospitals) formed the development cohort, and 4 systems (5 hospitals) constituted the validation …


An Acoustofluidic Device For Sample Preparation And Detection Of Small Extracellular Vesicles, Jessica F. Liu, Jianping Xia, Joseph Rich, Shuaiguo Zhao, Kaichun Yang, Brandon Lu, Ying Chen, Tiffany Wen Ye, Tony Jun Huang Jul 2025

An Acoustofluidic Device For Sample Preparation And Detection Of Small Extracellular Vesicles, Jessica F. Liu, Jianping Xia, Joseph Rich, Shuaiguo Zhao, Kaichun Yang, Brandon Lu, Ying Chen, Tiffany Wen Ye, Tony Jun Huang

Faculty Publications

Small extracellular vesicles (sEVs) have emerged as powerful vectors for liquid biopsy, offering a noninvasive window into the dynamic physiological and pathological states of the body. However, to fully leverage the clinical potential of sEV biomarkers, it is imperative to develop robust and efficient technologies for their isolation and analysis. In this study, we introduce a novel sharp-edge acoustofluidic platform designed for rapid and effective sample preparation, coupled with sensitive detection of specific sEV populations based on their surface markers. Our approach utilizes acoustically activated sharp-edge microstructures to concentrate bead-bound sEVs within the microfluidic device, facilitating immediate visualization by fluorescence …


A Rapid Method For Identifying Plant Oxidative Stress And Implications For Riparian Vegetation Management, Mizanur Rahman, Takashi Asaeda, Kiyotaka Fukahori, Md Harun Rashid, Hideo Kawashima, Junichi Akimoto, Refah Tabassoom Anta Jul 2025

A Rapid Method For Identifying Plant Oxidative Stress And Implications For Riparian Vegetation Management, Mizanur Rahman, Takashi Asaeda, Kiyotaka Fukahori, Md Harun Rashid, Hideo Kawashima, Junichi Akimoto, Refah Tabassoom Anta

School of Earth, Environmental, & Marine Sciences Faculty Publications

Native and invasive plants of the riverain region undergo a range of environmental stresses that result in excess reactive oxygen species (ROS). Hydrogen peroxide (H2O2) is a relatively stable and quickly quantifiable way among different ROS. The herbaceous species including Artemisia princeps, Sicyos angulatus, and Solidago altissima were selected. The H2O2 and photosynthetic pigment of leaves were measured, soil samples were analyzed to quantify macronutrients such as total nitrogen (TN), total phosphorus (TP), and soil moisture, and photosynthetic photon flux density (PPFD) was also recorded at different observed sites of Arakawa Tarouemon, Japan. The H2O2 concentration of S. altissima significantly …


Nrg Oncology Liver Proton Sbrt And Hypofractionated Radiation Therapy: Current Treatment Technical Assessment And Practice Patterns, Minglei Kang, Paige A Taylor, Jiajian Shen, Jun Zhou, Jatinder Saini, Theodore S Hong, Kristin Higgins, Wei Liu, Ying Xiao, Charles B Simone, Liyong Lin Jul 2025

Nrg Oncology Liver Proton Sbrt And Hypofractionated Radiation Therapy: Current Treatment Technical Assessment And Practice Patterns, Minglei Kang, Paige A Taylor, Jiajian Shen, Jun Zhou, Jatinder Saini, Theodore S Hong, Kristin Higgins, Wei Liu, Ying Xiao, Charles B Simone, Liyong Lin

Faculty, Staff and Student Publications

No abstract provided.


The Local Neighborhood Interactions Shaping Tree Communities Through Ecological Disturbance And Environmental Change, Cole Doolittle Jul 2025

The Local Neighborhood Interactions Shaping Tree Communities Through Ecological Disturbance And Environmental Change, Cole Doolittle

Dissertations (1934 -)

My dissertation consists of four chapters focused on understanding the factors maintaining local species diversity, addressing a central goal of ecology increasingly critical for preserving ecosystem services and human well-being in the face of climate change. Specifically, I investigate how local neighborhoods – that is, the spatial arrangement, density, and identity of nearby competitors – contribute to patterns of growth and survival along gradients of ecological disturbance and environmental change using forest tree communities as a study system. In my first chapter, I develop a conceptual framework that synthesizes why we may expect local neighborhood interactions to weaken under ecological …


Correlated Sampling Of Parallel Partial And Linked Emulators For Geophysical Applications, Joseph Lyon Jul 2025

Correlated Sampling Of Parallel Partial And Linked Emulators For Geophysical Applications, Joseph Lyon

Dissertations (1934 -)

Computer models, or simulators, are mathematical representations of real world phenomena that, to run at new input settings, are often computationally intensive and prohibitively slow. Surrogate models, or emulators, provide a method of rapidly predicting simulator outputs with uncertainty at untested configurations by treating the computer model output as a single realization of a stochastic process, specifically a Gaussian Process (GP).In this dissertation, we consider three projects: Correlated Linked GP Emulation, Spatially Correlated Parallel Partial Emulation, and Optimizing the Zero-censored Gaussian Process with Spatially Correlated Sampling. First, the Correlated Linked Emulator, focuses on developing a model for the covariance of …


Efficacy Of A Novel Bcl-Xl Degrader, Dt2216, In Preclinical Models Of Jak2-Mutated Post-Mpn Aml, Zhe Wang, Anna Skwarska, Gowri Poigaialwar, Sovira Chaudhry, Alba Rodriguez-Meira, Pinpin Sui, Emmanuel Olivier, Yannan Jia, Varun Gupta, Warren Fiskus, Cassandra L Ramage, Guangrong Zheng, Alexandra Schurer, Kira Gritsman, Eirini P Papapetrou, Kapil Bhalla, Daohong Zhou, Adam J Mead, Raajit K Rampal, Jeffrey W Tyner, Hussein A Abbas, Naveen Pemmaraju, Qi Zhang Tatarata, Marina Konopleva Jul 2025

Efficacy Of A Novel Bcl-Xl Degrader, Dt2216, In Preclinical Models Of Jak2-Mutated Post-Mpn Aml, Zhe Wang, Anna Skwarska, Gowri Poigaialwar, Sovira Chaudhry, Alba Rodriguez-Meira, Pinpin Sui, Emmanuel Olivier, Yannan Jia, Varun Gupta, Warren Fiskus, Cassandra L Ramage, Guangrong Zheng, Alexandra Schurer, Kira Gritsman, Eirini P Papapetrou, Kapil Bhalla, Daohong Zhou, Adam J Mead, Raajit K Rampal, Jeffrey W Tyner, Hussein A Abbas, Naveen Pemmaraju, Qi Zhang Tatarata, Marina Konopleva

Faculty, Staff and Student Publications

Acute myeloid leukemia (AML) that evolves from myeloproliferative neoplasm (MPN) is known as post-MPN AML. Current treatments do not significantly extend survival beyond 12 months. B-cell lymphoma-extra large (BCL-xL) has been found to be overexpressed in leucocytes from patients with MPN, making it a potential therapeutic target. We investigated the role of BCL-xL in post-MPN AML and tested the efficacy of DT2216, a platelet-sparing BCL-xL proteolysis-targeting chimera, in preclinical models of post-MPN AML. We found that BCL2L1, the gene encoding BCL-xL, is expressed at higher levels in patients with post-MPN AML than in those with de novo AML. Single-cell multiomics …


Money And Social Exclusion In Networks, Maria Bigoni, Gabriele Camera, Edoardo Gallo Jul 2025

Money And Social Exclusion In Networks, Maria Bigoni, Gabriele Camera, Edoardo Gallo

ESI Working Papers

Globalization offers unparalleled opportunities to expand welfare through cooperation across large networks of unrelated individuals. Social exclusion – permanent or temporary – and monetary exchange are institutions that in theory can incentivize cooperation. In an experiment, we evaluate their relative performance and interaction in anonymous networks of different sizes. Permanent social exclusion (ostracism) reduces long-run economic potential by leading to sparse networks. Monetary exchange and temporary social exclusion perform similarly well in small networks. In large networks, however, monetary exchange is the only institution that promotes full cooperation by crowding out ostracism and keeping the network complete. An insight is …


Cover And Contents Jul 2025

Cover And Contents

Turkish Journal of Zoology

No abstract provided.


Comparative Mitogenomics Of Clitellata Reveals Mitogenome Organization Can Affect The Mode Of Phylogeny, Deni̇z Mercan, Austin Horenkamp, Merve Nur Aydemi̇r, Habeş Bi̇lal Aydemi̇r, Kurt Neubig, Nai̇me Arslan, Frank E. Anderson Jul 2025

Comparative Mitogenomics Of Clitellata Reveals Mitogenome Organization Can Affect The Mode Of Phylogeny, Deni̇z Mercan, Austin Horenkamp, Merve Nur Aydemi̇r, Habeş Bi̇lal Aydemi̇r, Kurt Neubig, Nai̇me Arslan, Frank E. Anderson

Turkish Journal of Zoology

Clitellata is a major clade of Annelida that includes almost all freshwater and terrestrial annelids as well as many marine species. Aquatic oligochaetes include the union of the two multispecies families: Naididae and Tubificidae. There has been much debate regarding the phylogeny and classification of the cosmopolitan and diverse Naididae. In this study, the total mitogenome sequences of Potamothrix hammoniensis (Naididae: Tubificinae), Stylaria fossularis, Stylaria lacustris, Chaetogaster diaphanus, Chaetogaster diaphanus sp. B, and Slavina appendiculata (Naididae: Naidinae) were sequenced and characterized and can be accessed from NCBI under accession numbers OQ654101, PP909790, PP909791, PP909792, PP909793, and PP893275, respectively. For comparative …


Reproductive Dynamics Of Diplostraca In The Black Sea: Insights From Hamsilos Bay, Sinop, Türkiye, Funda Üstün Jul 2025

Reproductive Dynamics Of Diplostraca In The Black Sea: Insights From Hamsilos Bay, Sinop, Türkiye, Funda Üstün

Turkish Journal of Zoology

In the coastal marine ecosystem of the Black Sea, Diplostraca is the second most dominant mesozooplankton after Copepoda. Its parthenogenetic reproductive strategy enables significant population growth from spring (March) to fall (December), contributing substantially to mesozooplankton abundance. This study investigated the fecundity, embryonic development stages, and population structure of four of Diplostraca species in Hamsilos Bay: Evadne spinifera, Pleopis polyphemoides, Penilia avirostris, and Pseudevadne tergestina. Samples were taken every month from three stations between July 2015 and June 2016. Population analysis showed that parthenogenetic females were dominant, reaching up to 100% of the population. Gamogenetic females, females without embryos, and …


Effects Of Dietary Supplementation With Codium Fragile And Fennel Essential Oil On Growth, Enzyme Activity, And Hepatopancreas Histology In Juvenile Narrow-Clawed Crayfish (Pontastacus Leptodactylus Eschscholtz, 1823), Yavuz Mazlum, Meti̇n Yazici, Şehri̇ban Çek, Mehmet Naz, Musa Türkmen, Oğuz Yaşar Uzunmehmetoğlu, Kemal Dede Jul 2025

Effects Of Dietary Supplementation With Codium Fragile And Fennel Essential Oil On Growth, Enzyme Activity, And Hepatopancreas Histology In Juvenile Narrow-Clawed Crayfish (Pontastacus Leptodactylus Eschscholtz, 1823), Yavuz Mazlum, Meti̇n Yazici, Şehri̇ban Çek, Mehmet Naz, Musa Türkmen, Oğuz Yaşar Uzunmehmetoğlu, Kemal Dede

Turkish Journal of Zoology

This study investigated the impact of different levels of Codium fragile macroalgae (CF) dietary supplementation combined with a fixed concentration of 0.05% fennel (Foeniculum vulgare Mill. var. dulce Mill.) essential oil (FO) on the growth performance, enzyme activity, and hepatopancreas histological changes of juvenile narrow-clawed crayfish Pontastacus leptodactylus (initial average weight = 0.25 ± 0.04 g). A 90-day feeding trial was conducted using four experimental groups: CF + FO (control), 1% CF + FO, 2% CF + FO, and 4% CF + FO. The essential oil yield obtained from the fennel seeds was 2.4%. Anethole was the most abundant component …


Monitoring And Control Of Red Palm Weevil Infestation Using Iot Technology, Harun Çi̇men, İbrahi̇m Çakmak, Mustapha Touray, Selçuk Hazir Jul 2025

Monitoring And Control Of Red Palm Weevil Infestation Using Iot Technology, Harun Çi̇men, İbrahi̇m Çakmak, Mustapha Touray, Selçuk Hazir

Turkish Journal of Zoology

Palms are slow-growing arboreal monocots predominantly distributed across warm regions and are frequently incorporated into parks, gardens, and roadsides. The red palm weevil, Rhynchophorus ferrugineus, is a highly destructive invasive insect that threatens palms. This field study investigated the effectiveness of a seismic sensor system to detect R. ferrugineus larvae on palm trees in the İzmir Metropolitan Municipality Culture Park. This park is home to a diverse collection of palm species, including Washingtonia sp. and Phoenix dactylifera. Seismic sensors were attached to the trunks of palm trees to detect the vibrations caused by feeding R. ferrugineus larvae and calibrated to …


Winter Breeding Of The Long-Eared Owl (Asio Otus) In Türkiye, Alaz Uslu, Gencer Yaprak, Sali̇h Tora Benzeyen, Alper Tüydeş, İbrahi̇m Kaan Özgenci̇l Jul 2025

Winter Breeding Of The Long-Eared Owl (Asio Otus) In Türkiye, Alaz Uslu, Gencer Yaprak, Sali̇h Tora Benzeyen, Alper Tüydeş, İbrahi̇m Kaan Özgenci̇l

Turkish Journal of Zoology

The long-eared owl (Asio otus) is a widespread nocturnal raptor found across the Holarctic, inhabiting a variety of wooded habitats with adjacent open areas. While the species is not globally threatened, its population is declining, which is primarily attributed to threats such as habitat degradation, pesticide use, hunting, and disturbance. Although winter breeding has been documented in several European countries, no such records have been reported from Türkiye up to date. In this study, we compiled 11 records of winter breeding long-eared owls from northwest and central Türkiye, based on our field observations and data from rehabilitation centers. The estimated …


The First Documented Case Of Melanism In Sciurus Anomalus, Recorded In Türkiye, Burak Akdağ, Balkan Mega Jul 2025

The First Documented Case Of Melanism In Sciurus Anomalus, Recorded In Türkiye, Burak Akdağ, Balkan Mega

Turkish Journal of Zoology

This study reports the first documented case of melanism in the Caucasian squirrel (Sciurus anomalus) from Türkiye. While melanism has been documented in 12 other species within the Sciurus genus, it has not previously been recorded in S. anomalus. The observation was made during a herpetological field survey in Erzincan Province, Türkiye, where a melanistic specimen was photographed in a mixed habitat comprising natural vegetation and cultivated land. In mammals, melanism is widely regarded as an adaptive trait, potentially conferring advantages such as improved thermoregulation in colder climates and enhanced crypsis in shaded forest environments. This novel observation not only …


Risk Factors For In-Stent Stenosis After Flow-Diverter Implantation For Intracranial Aneurysm: A Single Center Analysis Of 161 Consecutive Patients, Rabab Alshahrani, Spyridon Karadimas, Mohammed Ali Alvi, Patrick Joseph Nicholson, Timo Krings Jul 2025

Risk Factors For In-Stent Stenosis After Flow-Diverter Implantation For Intracranial Aneurysm: A Single Center Analysis Of 161 Consecutive Patients, Rabab Alshahrani, Spyridon Karadimas, Mohammed Ali Alvi, Patrick Joseph Nicholson, Timo Krings

Department of Neurosurgery Faculty Papers

INTRODUCTION: Flow diverters (FD) are used for the treatment of intracranial aneurysms, by redirecting flow and serving as a scaffold for endothelial coverage of the aneurysm ostium. However, in-stent stenosis has been observed in some patients treated with these devices, the cause of which and the epidemiology remaining elusive. In the current study we aimed to elucidate potential factors leading to higher degree of in-stent stenosis including gender, location, and type of FD.

METHODS: The authors queried their institutional Electronic Health Record (EHR) for all patients undergoing FD for intracranial saccular aneurysms. We excluded cases where an FD was performed …


July 17, 2025 Minutes, Swosu Faculty Senate Jul 2025

July 17, 2025 Minutes, Swosu Faculty Senate

Faculty Senate Minutes

No abstract provided.


Electrophysiological Characterization Of Sex-Dependent Hypnosis By An Endogenous Neuroactive Steroid Epipregnanolone, Tamara Timic Stamenic, Ian Coulter, Douglas F Covey, Slobodan M Todorovic Jul 2025

Electrophysiological Characterization Of Sex-Dependent Hypnosis By An Endogenous Neuroactive Steroid Epipregnanolone, Tamara Timic Stamenic, Ian Coulter, Douglas F Covey, Slobodan M Todorovic

2020-Current year OA Pubs

Neuroactive steroids (NAS) have long been recognized for their hypnotic and anesthetic properties in both clinical and preclinical settings. While sex differences in NAS sensitivity are acknowledged, the underlying mechanisms remain poorly understood. Here, we examined sex-specific responses to an endogenous NAS epipregnanolone (EpiP) in wild-type mice using behavioral assessment of hypnosis (loss of righting reflex, LORR) and in vivo electrophysiological recordings. Specifically, local field potentials (LFPs) were recorded from the central medial thalamus (CMT) and electroencephalogram (EEG) signals were recorded from the barrel cortex. We found that EpiP-induced LORR exhibited clear sex differences, with females showing increased sensitivity. Spectral …


Reducing Foreign Language Anxiety Through Cooperative Learning: Enhancing Speaking Skills For Bipa Learners, Mahira Mujahida Ani Mufti, Lilis Siti Sulistyaningsih, Mochamad Whilky Rifkiyanfi Jul 2025

Reducing Foreign Language Anxiety Through Cooperative Learning: Enhancing Speaking Skills For Bipa Learners, Mahira Mujahida Ani Mufti, Lilis Siti Sulistyaningsih, Mochamad Whilky Rifkiyanfi

Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya

Indonesia's economic and political development has sparked global interest, contributing to the increasing status of Indonesian as an international language. This has led to a growing number of learners in the BIPA (Bahasa Indonesia for Foreign Speakers) program. While many studies have focused on learning materials, media, models, and evaluation tools, research on foreign language anxiety in the BIPA context remains limited. This study investigates the effectiveness of cooperative strategies in reducing language anxiety and improving speaking skills among BIPA Level 1 students. Using a quantitative Single Subject Research (SSR) method with an A-B-A design, the study involved three purposively …


Synthesis Of Cancrinite Zeolite From Toraja Natural Bentonite For Heavy Metal Removal From Wastewater, Yuli Astuti, Paulina Taba, Siti Fauziah, Syarifuddin Liong, Yusafir Hala, Nur Umriani Permatasari, Satria Putra Jaya Negara, Fadliah Fadliah Jul 2025

Synthesis Of Cancrinite Zeolite From Toraja Natural Bentonite For Heavy Metal Removal From Wastewater, Yuli Astuti, Paulina Taba, Siti Fauziah, Syarifuddin Liong, Yusafir Hala, Nur Umriani Permatasari, Satria Putra Jaya Negara, Fadliah Fadliah

Karbala International Journal of Modern Science

This study explores the production of cancrinite (CAN) zeolite from bentonite found in Toraja (a place in South Sulawesi Province, Indonesia) and its effectiveness in removing Pb2+ and Fe3+ ions from wastewater. The synthesis was carried out using a hydrothermal method with varying NaOH concentrations, where a single phase of zeolite was formed at 5 M, as confirmed through XRD analysis. FTIR results showed the characteristics of CAN zeolite with typical absorption peaks at 676, 622, and 565 cm-1, as well as the presence of carbonate groups (CO₃2-) at 1300-1400 cm-1. SEM …


Machine Learning Crime Prediction Models And The Gap Between Research And Implementation: A Systematic Review, Ricardo Huamantingo, Miguel Cano-Lengua, Ciro Rodriguez Jul 2025

Machine Learning Crime Prediction Models And The Gap Between Research And Implementation: A Systematic Review, Ricardo Huamantingo, Miguel Cano-Lengua, Ciro Rodriguez

Karbala International Journal of Modern Science

A crime is an illegal or violent act committed by one individual against another. The increasing crime rate has become a major concern as it negatively affects people's quality of life and generates significant social and economic costs. This study aims to identify the most widely used machine learning (ML) models for crime prediction, determine evaluation metrics for assessing model performance, and analyze key data characteristics to enhance real-world implementation. The study follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology. A search string was formulated using the population, intervention, comparison, and outcomes (PICO) framework and applied …


Psilostachyin B As Potential Immune Checkpoint Inhibitor Targeting Ctla-4 And Pd-L1 In The Development Of Cancer Immunotherapy: A Computational Investigation, Moh Dliyauddin, Nabila Shafa Yumna Salsabila, Noviana Dwi Lestari, Sapti Puspitarini, Mansur Ibrahim, Sri Rahayu, Muhammad Sasmito Djati, Muhaimin Rifa’I Jul 2025

Psilostachyin B As Potential Immune Checkpoint Inhibitor Targeting Ctla-4 And Pd-L1 In The Development Of Cancer Immunotherapy: A Computational Investigation, Moh Dliyauddin, Nabila Shafa Yumna Salsabila, Noviana Dwi Lestari, Sapti Puspitarini, Mansur Ibrahim, Sri Rahayu, Muhammad Sasmito Djati, Muhaimin Rifa’I

Karbala International Journal of Modern Science

Immunotherapy is a promising treatment approach by targeting immune checkpoints such as CTLA-4 and PD-L1 to overcome cancer progression. The utilization of Curcuma longa and Phyllanthus niruri as potential immune checkpoint inhibitors offers an alternative cancer therapy. Computational analyses including molecular docking and molecular dynamics with validation using Molecular Mechanics/Poisson-Boltzmann Surface Area (MM-PBSA), Dynamic Cross-Correlation Matrix (DCCM), and Principal Component Analysis (PCA), were performed in this study. Results show that Psilostachyin B is the most promising inhibitor candidate against CTLA-4 and PD-L1, with binding affinity values of -6.9 and -6.8 kcal/mol, respectively. Molecular dynamics simulation results indicated that Psilostachyin B …


Machine Learning Modeling Approaches For Predicting The Extent Of Fatigue Damage In Polycrystalline Alloy Structures, Hassan Alqahtani Jul 2025

Machine Learning Modeling Approaches For Predicting The Extent Of Fatigue Damage In Polycrystalline Alloy Structures, Hassan Alqahtani

Yanbu Journal of Engineering and Science

Using predictions of crack-tip-opening-displacement (CTOD) to measure the extent of fatigue damage has provided the opportunity to prepare an efficient strategy for protecting mechanical structures from damage and developing a structural health monitoring system. The objective is to forecast non-measurable CTOD by using machine learning methods. In this paper, an optical metrology device, which is built by Alicona on a confocal microscope and hereafter referred to as Confocal Microscope, has been used to measure CTOD. However, two factors limit the usage of Alicona Apparatus: (i) the size of optical images, where a CTOD over 400 micrometers cannot be measured; and …


Public Safety In Smart Cities: An Experimental Study To Monitor And Record Vehicles’ Movements, Ali A. Albar, Mirza A. Baig Jul 2025

Public Safety In Smart Cities: An Experimental Study To Monitor And Record Vehicles’ Movements, Ali A. Albar, Mirza A. Baig

Yanbu Journal of Engineering and Science

This research addresses the critical issue of enhancing public safety in smart cities, with a particular focus on industrial cities in Saudi Arabia. Despite the advanced infrastructure and high safety standards in industrial cities, there are safety challenges, particularly the vulnerability of residential properties to burglaries during holidays and extended breaks. To mitigate these risks, the research proposes leveraging existing infrastructure to implement surveillance systems that monitor vehicle movements using RFID technology and smart sensors, thereby enhancing safety, supporting law enforcement in crime detection, and protecting local communities. The study also acknowledges the reduced social interaction often associated with the …