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Board Of Trustees Minutes, Jul. 25 2025, Indiana State University Board Of Trustees Jul 2025

Board Of Trustees Minutes, Jul. 25 2025, Indiana State University Board Of Trustees

Board of Trustees

No abstract provided.


Permeability Evolutionary Patterns Of Fractured Rock Masses In Fault Zones Under Seepage-Stress Coupling, Zhao Dekang, Han Bing, Zeng Yifan, Feng Guorui, Xi Yonghong, Chang Bofeng, Li Zhenghao, Wang Pengwei, Wang Lisan Jul 2025

Permeability Evolutionary Patterns Of Fractured Rock Masses In Fault Zones Under Seepage-Stress Coupling, Zhao Dekang, Han Bing, Zeng Yifan, Feng Guorui, Xi Yonghong, Chang Bofeng, Li Zhenghao, Wang Pengwei, Wang Lisan

Coal Geology & Exploration

Background In coal mines, fault structures serve as critical pathways for water inrushes from coal seam floors, posing serious threats to the production safety of mines. Delving into the permeability evolutionary patterns of fractured rock masses in fault zones under seepage-stress coupling holds great significance for the prevention and control of water inrushes along faults from coal seam floors.Methods Against the engineering background of the Gaohe Coal Mine under the Shanxi Lu’an Mining (Group) Co., Ltd. in Shanxi Province, this study analyzed the microscopic physical properties and the pore and fracture structures of a fractured rock mass in a …


Inhibition Of The Caveolin-1 Pathway Promotes Apoptosis And Overcomes Pan-Tyrosine Kinase Inhibitor Resistance In Hepatocellular Carcinoma, Tasnuva D. Kabir, Samuel Beck, Lisa M. Stuart, Ji Li, Rui Hou, Peiwen Liu, Shelby Margolius, Claire Kim, Yu Suk Choi, Edward R. Bastow, Dianne J. Beveridge, Lisa Spalding, Ziyi Li, Florent Ginhoux, Pierce Chow, Michael Phillips, Andrew D. Redfern, George C. Yeoh, Alistair Forrest, Andrew J. Woo, Ankur Sharma, Jacob George, Geoffrey Mccaughan, Peter Leedman Jul 2025

Inhibition Of The Caveolin-1 Pathway Promotes Apoptosis And Overcomes Pan-Tyrosine Kinase Inhibitor Resistance In Hepatocellular Carcinoma, Tasnuva D. Kabir, Samuel Beck, Lisa M. Stuart, Ji Li, Rui Hou, Peiwen Liu, Shelby Margolius, Claire Kim, Yu Suk Choi, Edward R. Bastow, Dianne J. Beveridge, Lisa Spalding, Ziyi Li, Florent Ginhoux, Pierce Chow, Michael Phillips, Andrew D. Redfern, George C. Yeoh, Alistair Forrest, Andrew J. Woo, Ankur Sharma, Jacob George, Geoffrey Mccaughan, Peter Leedman

Research outputs 2022 to 2026

Resistance to multi-tyrosine kinase inhibitors (TKI) is a major clinical concern in advanced hepatocellular carcinoma (HCC). Herein, we aimed to uncover the mechanisms underlying pan-TKI resistance and to identify potential therapeutic targets. We used multiple TKI-resistant HCC cell lines to identify caveolin-1 (CAV1) as a key driver of therapeutic resistance. CAV1 downregulation induced apoptosis, inhibited metastasis and restored TKI sensitivity in both inherent and acquired TKI-resistant HCC cells. Mechanistically, in acquired TKI-resistant cells aberrant CAV1/STAT3/P70S6K signalling is required for their survival, motility, and invasiveness. CAV1 inhibition reduced expression of dormancy regulators E-cadherin, RAC1 and p21, enhanced cancer stemness markers, and …


Electromyographic Analysis Of Lower Limb Muscles During Multi-Joint Eccentric Isokinetic Exercise Using The Eccentron Dynamometer, Brennan J. Thompson, Merrill Ward, Brayden Worley, Talin Louder Jul 2025

Electromyographic Analysis Of Lower Limb Muscles During Multi-Joint Eccentric Isokinetic Exercise Using The Eccentron Dynamometer, Brennan J. Thompson, Merrill Ward, Brayden Worley, Talin Louder

Kinesiology and Health Science Faculty Publications

Eccentric muscle actions are integral to human movement, rehabilitation, and performance training due to their characteristic high force output (overload) and low energy cost and perceived exertion. Despite the growing use of eccentric devices, a gap in the research exists exploring multi-muscle activation profiles during multi-joint eccentric-only, isokinetic exercise. This study aimed to quantify and compare surface electromyographic (EMG) activity of four leg muscles—vastus lateralis (VL), tibialis anterior (TA), biceps femoris (BF), and medial gastrocnemius (GM)—during a standardized (isokinetic) submaximal eccentric multi-joint exercise using the Eccentron dynamometer. Eighteen healthy adults performed eccentric exercise at 40% of their maximal eccentric strength. …


The Council Of Nicaea At 1700, Kyle K. Schiefelbein-Guerrero Jul 2025

The Council Of Nicaea At 1700, Kyle K. Schiefelbein-Guerrero

Consensus

No abstract provided.


The Nicene Creed And Evangelical Lutheranism For The Twenty-First Century, Allan J. Ferguson Jul 2025

The Nicene Creed And Evangelical Lutheranism For The Twenty-First Century, Allan J. Ferguson

Consensus

No abstract provided.


The Nicene Creed And The Question Of The Filioque In Conversations Between Lutherans And Orthodox Christians In North America: 1993–2003, Thomas R. Lee Jul 2025

The Nicene Creed And The Question Of The Filioque In Conversations Between Lutherans And Orthodox Christians In North America: 1993–2003, Thomas R. Lee

Consensus

No abstract provided.


Lutherans And The Nicene Creed: Liturgy And Music, Paul Westermeyer Jul 2025

Lutherans And The Nicene Creed: Liturgy And Music, Paul Westermeyer

Consensus

No abstract provided.


Welcoming Strangers Into Relationship: A Sermon For Trinity Sunday, Kayko Driedger Hesslein Jul 2025

Welcoming Strangers Into Relationship: A Sermon For Trinity Sunday, Kayko Driedger Hesslein

Consensus

No abstract provided.


Sermon For Truth And Reconciliation, Scott Knarr Jul 2025

Sermon For Truth And Reconciliation, Scott Knarr

Consensus

No abstract provided.


Creation Series: Sky, Laura Sauder Jul 2025

Creation Series: Sky, Laura Sauder

Consensus

No abstract provided.


The Triune God Spills Into Creation, Calling Us To Love One Another, Kyle Schiefelbein-Guerrero Jul 2025

The Triune God Spills Into Creation, Calling Us To Love One Another, Kyle Schiefelbein-Guerrero

Consensus

No abstract provided.


Need To Figure Out How To Have A Difficult Conversation? Open Your Bible!, Angela Yensen Jul 2025

Need To Figure Out How To Have A Difficult Conversation? Open Your Bible!, Angela Yensen

Consensus

No abstract provided.


The Diviners: A Play, Jeffrey Dale Jul 2025

The Diviners: A Play, Jeffrey Dale

Consensus

Thiessen, V., Barker, K., Nolan, Y., & Laurence, M. (2024). The diviners : a play. Scirocco Drama. ISBN: 9781990738593


Who We Are: Four Questions For A Life And A Nation, Joe Gunn Jul 2025

Who We Are: Four Questions For A Life And A Nation, Joe Gunn

Consensus

Sinclair, M., Sinclair, S., & Sinclair, N. J. (2024). Who we are: four questions for a life and a nation. McClelland & Stewart. ISBN: 9780771099106


Mindfulness Techniques And Practices In Islamic Psychotherapy: The Power Of Mu-Raqabah, Sehrish Haroon Jul 2025

Mindfulness Techniques And Practices In Islamic Psychotherapy: The Power Of Mu-Raqabah, Sehrish Haroon

Consensus

Isgandarova, N. (2025). Mindfulness techniques and practices in Islamic psychotherapy : the power of muraqabah. Routledge. ISBN: 9781032631387


Done: How To Flourish After Leaving Religion, Allen Jorgenson Jul 2025

Done: How To Flourish After Leaving Religion, Allen Jorgenson

Consensus

Van Tongeren, D. R. (2024). Done : how to flourish after leaving religion. American Psychological Association. ISBN: 9781433836237


More Everything Forever: Ai Overlords, Space Empires, And Silicon Valley’S Crusade To Control The Fate Of Humanity, Joseph Kirby Jul 2025

More Everything Forever: Ai Overlords, Space Empires, And Silicon Valley’S Crusade To Control The Fate Of Humanity, Joseph Kirby

Consensus

Becker, A. (2025). More everything forever : AI overlords, space empires, and Silicon Valley’s crusade to control the fate of humanity. Basic Books. ISBN: 9781541619593


Values: Building A Better World For All, John Milloy Jul 2025

Values: Building A Better World For All, John Milloy

Consensus

Carney, M. (2021). Value(s) : building a better world for all (Paperback edition). Signal/McClelland & Stewart. ISBN: 9780771051579


Spiritual, Philosophical, And Psychotherapeutic Engagements Of Meaning And Service, Bradley Morrison Jul 2025

Spiritual, Philosophical, And Psychotherapeutic Engagements Of Meaning And Service, Bradley Morrison

Consensus

Harper, K., O’Connor, T. S. J., & Maoz, D. (2024). Spiritual, philosophical, and psychotherapeutic engagements of meaning and service. Cambridge Scholars Publishing. ISBN: 9781036402822


Handbook Of Spiritually Integrated Psychotherapies, Thomas St. James O'Connor Jul 2025

Handbook Of Spiritually Integrated Psychotherapies, Thomas St. James O'Connor

Consensus

Richards, P. S., Allen, G. E. K., & Judd, D. K. (2023). Handbook of spiritually integrated psychotherapies. American Psychological Association. ISBN: 9781433835933


Defending Democracy From Its Christian Enemies, David Pfrimmer Jul 2025

Defending Democracy From Its Christian Enemies, David Pfrimmer

Consensus

Gushee, D. P. (2023). Defending democracy from its Christian enemies. William B. Eerdmans Publishing Company. ISBN: 9781467466219


Usa V. Marcello Whyte Jul 2025

Usa V. Marcello Whyte

2025 Decisions

USDC for the Middle District of Pennsylvania


Multi-Objective Allocation Optimization Model For Water Resources From A Coal Mine In The Inner Mongolia-Shaanxi Contiguous Area, Miao Hechao, Dong Shuning, Wang Hao, Yang Yuanyuan, Qiao Wei, Wang Xiaodong, Wang Dongqi, Fu Hongyang, Liu Yuting Jul 2025

Multi-Objective Allocation Optimization Model For Water Resources From A Coal Mine In The Inner Mongolia-Shaanxi Contiguous Area, Miao Hechao, Dong Shuning, Wang Hao, Yang Yuanyuan, Qiao Wei, Wang Xiaodong, Wang Dongqi, Fu Hongyang, Liu Yuting

Coal Geology & Exploration

Objective In China, as coal resource exploitation shifts gradually from eastern to western regions, coal bases in the western region play an increasingly notable foundational role in the basic energy supply in the national economy. However, due to its fragile ecosystems, the safe, efficient, and green coal exploitation of this region has long been challenged by the contradiction between the prevention and control of water hazards and the conservation of water resources. Therefore, advancing intelligent mine water control technology is identified as a crucial method to address the conflicts between coal mining and mine water in the western region. Additionally, …


Groundwater Rebound And Seepage Characteristics And Water Quality Evolution In A Sealed Mining Area In North China Type Coalfield, Yin Huiyong, Sun Dehui, Dong Fangying, Wang Fanhua, Zhang Lifeng, Wu Tao, Liu Chao, Zeng Yifan Jul 2025

Groundwater Rebound And Seepage Characteristics And Water Quality Evolution In A Sealed Mining Area In North China Type Coalfield, Yin Huiyong, Sun Dehui, Dong Fangying, Wang Fanhua, Zhang Lifeng, Wu Tao, Liu Chao, Zeng Yifan

Coal Geology & Exploration

Background The seepage field and water quality evolution associated with the groundwater rebound induced by the sealing of mining areas significantly affects the prevention and control of mine water hazards, as well as the recycling of water resources. Systematically elucidating the mechanisms underlying the seepage-hydrochemistry synergy of groundwater is recognized as a fundamental scientific issue for promoting the collaborative management and resource development of the water systems in mining areas. Methods Based on the engineering background of the sealed No.116 mining area in the Binhu Coal Mine, Zaozhuang, Shandong Province, this study investigated the groundwater rebound and seepage characteristics, along …


Cocoa Polyphenols Modulate The Mouse Gut Microbiome In A Site-Specific Manner, Abby D. Benninghoff Jul 2025

Cocoa Polyphenols Modulate The Mouse Gut Microbiome In A Site-Specific Manner, Abby D. Benninghoff

Browse all Datasets

Background/Objectives: Dietary modulation of the gut microbiome is a promising strategy for mitigating gastrointestinal diseases, such as inflammatory bowel disease (IBD) and colitis-associated colorectal cancer (CAC). Cocoa powder is rich in polyphenols, including (-)-epicatechin and (+)-catechin, which have been associated with beneficial effects on gut health and microbiome modulation. Importantly, changes in the bacterial populations associated with the gut mucosal layer may have different health impacts compared to changes in cecal or fecal microbiomes. This study investigated the effects of cocoa polyphenol supplementation on microbiome composition across the cecal, fecal, and mucosal compartments in a mouse model of colitis. Methods: …


The Relationship Between Hand Grip Strength And Cognitive Function In Middle-Aged And Elderly People In China: A Cross-Sectional Analysis Based On Charls Data, Haiwei Li, Jing Zhang, Peipei Cheng, Liwei Guo, Xuemei Sui M.D., M.P.H., Ph.D. Jul 2025

The Relationship Between Hand Grip Strength And Cognitive Function In Middle-Aged And Elderly People In China: A Cross-Sectional Analysis Based On Charls Data, Haiwei Li, Jing Zhang, Peipei Cheng, Liwei Guo, Xuemei Sui M.D., M.P.H., Ph.D.

Faculty Publications

This study explores the relationship between hand grip strength (HGS) and cognitive function in China’s middle-aged and elderly population. We employed a cross-sectional design using data from 4535 participants aged ≥ 45 years from the 2015 China Health and Retirement Longitudinal Study national dataset. The relationships between HGS and various dimensions of cognitive function, as well as the association between HGS and cognitive impairment, were investigated using ordinary least squares regression models and logistic regression models. Dose–response relationships between HGS and cognitive impairment were modeled using restricted cubic spline curves. Subgroup and sensitivity analyses were performed to assess the robustness …


July 25, 2025 Ereporter, University Of Alabama At Birmingham Jul 2025

July 25, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Ud In The News July 19-25, University Of Dayton Jul 2025

Ud In The News July 19-25, University Of Dayton

News Releases

Sociologist Art Jipson wrote about how the QAnon movement entered mainstream politics for The Conversation. WHIO-TV and WDTN-TV in Dayton featured the ceremony swearing in new UD police chief Steve Durian.


Board Of Trustees Agenda, Jul. 25 2025, Indiana State University Board Of Trustees Jul 2025

Board Of Trustees Agenda, Jul. 25 2025, Indiana State University Board Of Trustees

Board of Trustees

No abstract provided.