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Delphinium Cut Flower Production In Utah, Nick Volesky, Melanie Stock Jul 2025

Delphinium Cut Flower Production In Utah, Nick Volesky, Melanie Stock

All Current Publications

Delphinium is a perennial crop that produces tall racemes in two flushes per season. Its long stems serve as vertical line elements, adding height and balance to floral arrangements. Popular series are available in striking shades of blue, which are not commonly found among cut flowers, making delphinium an excellent choice for local market production. This fact sheet provides an overview of how to grow, harvest, and store delphinium, including yields for various cultivars. It also covers its common pests and diseases, and reviews its economic value for cut flower producers.


Multiscale Modeling And Dynamic Mutational Profiling Of Binding Energetics And Immune Escape For Class I Antibodies With Sars-Cov-2 Spike Protein: Dissecting Mechanisms Of High Resistance To Viral Escape Against Emerging Variants, Mohammed Alshahrani, Vedant Parikh, Brandon Foley, Gennady M. Verkhivker Jul 2025

Multiscale Modeling And Dynamic Mutational Profiling Of Binding Energetics And Immune Escape For Class I Antibodies With Sars-Cov-2 Spike Protein: Dissecting Mechanisms Of High Resistance To Viral Escape Against Emerging Variants, Mohammed Alshahrani, Vedant Parikh, Brandon Foley, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

The rapid evolution of SARS-CoV-2 has underscored the need for a detailed understanding of antibody binding mechanisms to combat immune evasion by emerging variants. In this study, we investigated the interactions between Class I neutralizing antibodies—BD55-1205, BD-604, OMI-42, P5S-1H1, and P5S-2B10—and the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein using multiscale modeling, which combined molecular simulations with the ensemble-based mutational scanning of the binding interfaces and binding free energy computations. A central theme emerging from this work is that the unique binding strength and resilience to immune escape of the BD55-1205 antibody are determined by leveraging a broad epitope …


Insights From The Front Line: Uplifting Stories Of The Covid-19 Pandemic Through The Eyes Of The Public Health Workforce In Iowa, Heidi Haines, Amanda Sursely, Hanh Pham, Rylee Beltran, Daniel K. Sewell, Lina Tucker Reinders, Natoshia Askelson, Sarah Dixon, Kaitlin Emrich, Christine Estle, Michelle Lewis, Jimmy Reyes Jul 2025

Insights From The Front Line: Uplifting Stories Of The Covid-19 Pandemic Through The Eyes Of The Public Health Workforce In Iowa, Heidi Haines, Amanda Sursely, Hanh Pham, Rylee Beltran, Daniel K. Sewell, Lina Tucker Reinders, Natoshia Askelson, Sarah Dixon, Kaitlin Emrich, Christine Estle, Michelle Lewis, Jimmy Reyes

Faculty Publications

Introduction: SARS-CoV-2 was declared a pandemic in March 2020. Studies have characterized some of the negative impact of the pandemic on public health workers (PHW), but few have explored the strength and coping strategies used. Our study documents the experiences of PHW in Iowa during the pandemic. Methods: We used an innovative mixed methods data collection tool, SenseMaker® to gather stories from PHW in Iowa between March and July 2022. Participants provided additional data about their story via structured follow-up questions. We conducted descriptive analyses of the quantitative questions. A qualitative thematic and sentiment analysis was applied to all …


Conditional Optimal Sets And The Quantization Coefficients For Some Uniform Distributions, Evans Nyanney, Megha Pandey, Mrinal Kanti Roychowdhury Jul 2025

Conditional Optimal Sets And The Quantization Coefficients For Some Uniform Distributions, Evans Nyanney, Megha Pandey, Mrinal Kanti Roychowdhury

School of Mathematical & Statistical Sciences Faculty Publications

Bucklew and Wise (1982) showed that the quantization dimension of an absolutely continuous probability measure on a given Euclidean space is constant and equals the Euclidean dimension of the space, and the quantization coefficient exists as a finite positive number. By giving different examples, in this paper, we have shown that the quantization coefficients for absolutely continuous probability measures defined on the same Euclidean space can be different. We have taken uniform distribution as a prototype of an absolutely continuous probability measure. In addition, we have also calculated the conditional optimal sets of n-points and the nth conditional quantization errors …


Rishon Le-ẒIyyon, Winepress Park: Geomorphology And Sedimentology, Joel Roskin, Yotam Asscher Jul 2025

Rishon Le-ẒIyyon, Winepress Park: Geomorphology And Sedimentology, Joel Roskin, Yotam Asscher

Qadum: Journal of Excavation Reports from Israel

An extensive brown sandy double-unit sediment, draping large parts of the archaeological remains at the Winepress Park in Rishon Le-Ẓiyyon, is suggested to be associated with the previously reported, undated ʻEn Ha-Qore clay. Based on relative age port-OSL profiling, the depositional mechanism of this unit and the overlying sand is suggested to be related to late Holocene, dune-dammed winter ponds. These aeolian-fluvial dune-damming processes may have been partly triggered by intensive Byzantine human activity that may have led to sand mobilization.


Rishon Le-ẒIyyon, Winepress Park: The Coins, Helena Sokolov, Lior Sandberg Jul 2025

Rishon Le-ẒIyyon, Winepress Park: The Coins, Helena Sokolov, Lior Sandberg

Qadum: Journal of Excavation Reports from Israel

The excavation at the Winepress Park in Rishon Le-Ẓiyyon uncovered 26 bronze coins, 22 of which were identified. The coins range in date from the fourth century CE to the Umayyad period. The earliest coin is of Constantius II, dated to 341–346 CE, while the latest coins are Umayyad Post-Reform issues. The coin data is consistent with the archaeological context of the excavation and confirms the excavator’s conclusion that the site can be dated to the period of the sixth–ninth centuries CE.


Rishon Le-ẒIyyon, Winepress Park: Early Islamic Pottery / ראשון לציון, גן הגיתות: ממצא כלי החרס מן התקופה האסלאמית הקדומה, Hagit Torgë Jul 2025

Rishon Le-ẒIyyon, Winepress Park: Early Islamic Pottery / ראשון לציון, גן הגיתות: ממצא כלי החרס מן התקופה האסלאמית הקדומה, Hagit Torgë

Qadum: Journal of Excavation Reports from Israel

The excavations at the Winepress Park in Rishon Le-Ẓiyyon uncovered a large pottery assemblage dated to the Early Islamic period. The assemblage was discovered in three squares, in clay soil that was exposed after the sand dune covering the site was removed. The repertoire included simple bowls, open cooking pots, jars, jugs, a flask and an oil lamp. Most of the vessels were simple household wares, suggesting that during this period the site was a rural, possibly isolated, farmstead. The absence of glazed or imported vessels may indicate the poor economic status of its inhabitants. While most of the vessels …


Rishon Le-ẒIyyon, Winepress Park: Byzantine Pottery / ראשון לציון, גן הגיתות: ממצא כלי חרס מן התקופה הביזנטית, Aviva Bouchenino, Ayelet Dayan Jul 2025

Rishon Le-ẒIyyon, Winepress Park: Byzantine Pottery / ראשון לציון, גן הגיתות: ממצא כלי חרס מן התקופה הביזנטית, Aviva Bouchenino, Ayelet Dayan

Qadum: Journal of Excavation Reports from Israel

The excavations at the Winepress Park in Rishon Le-Ẓiyyon uncovered a large pottery assemblage dated to the Byzantine period, including locally produced bowls, casseroles, cooking pots and bag-shaped jars, as well as bowls imported from Asia Minor, Cyprus and Tunisia. The rich and varied assemblage uncovered at the site, along with architectural remains, may indicate that this was a residential area—possibly a farmhouse inhabited by tenant farmers who operated the nearby winepresses. The pottery vessels served as a primary dating tool and contributed to establishing the site’s chronology. The ceramic finds, together with the numerous repairs identified in the winepresses, …


Rishon Le-ẒIyyon, Winepress Park: Remains Of Agricultural Activity From The Byzantine And Early Islamic Periods And Remains From The Ottoman Period And The British Mandate Era / ראשון לציון, גן הגיתות: שרידי פעילות חקלאית מהתקופות הביזנטית והאסלאמית הקדומה ושרידים מהתקופה העות'מאנית ומימי המנדט הבריטי, Ayelet Dayan, Aviva Bouchenino Jul 2025

Rishon Le-ẒIyyon, Winepress Park: Remains Of Agricultural Activity From The Byzantine And Early Islamic Periods And Remains From The Ottoman Period And The British Mandate Era / ראשון לציון, גן הגיתות: שרידי פעילות חקלאית מהתקופות הביזנטית והאסלאמית הקדומה ושרידים מהתקופה העות'מאנית ומימי המנדט הבריטי, Ayelet Dayan, Aviva Bouchenino

Qadum: Journal of Excavation Reports from Israel

Five excavation seasons conducted in and around the archaeological Winepress Park in Rishon Le-Ẓiyyon uncovered the agricultural hinterland of a settlement active during the Byzantine and Early Islamic periods. The finds included architectural remains, three winepresses and several installations. The locally produced and imported domestic pottery from the Byzantine period suggests a residential zone—possibly a farmhouse—that likely served the tenants operating the nearby winepresses. The number and size of the winepresses indicate that wine production at the site was intended not only for local consumption but also for export. Activity at the site ceased during the Early Islamic period, when …


Humanization Strategy Of The Public Urban Space In Cairo, Rania Badawy Shokry Jul 2025

Humanization Strategy Of The Public Urban Space In Cairo, Rania Badawy Shokry

Mansoura Engineering Journal

An accurate scientific definition of the term “humanization of cities” has not yet crystallized, which refers the term to the word from which it is derived. She is "human". Obviously, anything contrary to it is inhuman; starting from wild nature or a life entirely dependent on vehicles. If a person cannot dispense with vehicles when carrying out his daily activities, then here we know that the standard of humanization in a place is low. However, if the planning of a city or neighborhood takes into account the needs of the population and the human standard, then the city may reach …


Study Habits And Examination Anxiety As Correlates Of Academic Performance Among Secondary School Students In Kwara State, Nigeria, Oyedotun Dolapo Ilori, Falilat A. Okesina, Patrick O. Akerele, Ifeoluwa Blessing Michael Jul 2025

Study Habits And Examination Anxiety As Correlates Of Academic Performance Among Secondary School Students In Kwara State, Nigeria, Oyedotun Dolapo Ilori, Falilat A. Okesina, Patrick O. Akerele, Ifeoluwa Blessing Michael

Buletin Konseling Inovatif

Examination anxiety and study habits seem to be a significant factor of academic performance. This study examined study habits and examination anxiety as correlates of academic performance among secondary school students in Kwara State, Nigeria. This study adopted a descriptive survey of correlational type. The population for the study consists of 235, 652 secondary school students, and the sample consists of 400 secondary school students. Two research questions were answered using frequency count, percentage and mean rank order while the three hypotheses formulated were tested using inferential statistics of Pearson’s Product Moment Correlation statistics (PPMC) and multiple regression analysis at …


Exploring Victorian Era Class And Culture: Representation Of The Working Class Through Joseph Skipsey's Poetry, Nathasya Josephine Jul 2025

Exploring Victorian Era Class And Culture: Representation Of The Working Class Through Joseph Skipsey's Poetry, Nathasya Josephine

International Journal of Undergraduate Research and Creative Activities

Representation of minorities has always been a problem in publication. This is especially true in Victorian society, where class stratification was rampant and class distinctions were marked as normal. As a result, many authors from underprivileged communities are overshadowed by the influential literary giants we now know as the Canons. This paper aims to shed light on one of the unknown voices representing Victorian working-class society. Specifically, it will discuss Joseph Skipsey, a working-class author who writes poems about his daily life and struggles as a miner. The focus will be on two of his poems: "Get Up" and The …


Thyrotoxicosis In Pregnancy Cured By Total Thyroidectomy, Owen G. Alvine, Daniel Thum Md Jul 2025

Thyrotoxicosis In Pregnancy Cured By Total Thyroidectomy, Owen G. Alvine, Daniel Thum Md

Aesculapius Journal (Health Sciences & Medicine)

Thyrotoxicosis during pregnancy is a rare but potentially life-threatening condition that requires prompt recognition and management. This case report describes a 23-year-old pregnant woman with a history of Graves’ disease who presented with symptoms of thyrotoxicosis, including tachycardia, weight loss, and dyspnea. Initial treatment with propylthiouracil and propranolol was insufficient, and her condition progressed to include pericardial effusion with early tamponade physiology and systemic inflammatory response syndrome (SIRS). Despite medical therapy, her symptoms persisted, necessitating a total thyroidectomy during the second trimester. Postoperatively, the patient experienced significant clinical improvement and delivered a healthy infant at term. This case highlights the …


What The Desert Knows About Me, Isaiah Kronemeyer Jul 2025

What The Desert Knows About Me, Isaiah Kronemeyer

Night Flight: Online Literary Journal

What the Desert Knows About Me is a poem about carrying things that don't quite leave you, even when you try to bury them. Set in the quiet, unforgiving space of the desert, the writer reflects on moments of regret, loss, and silence that have taken root over time. The desert becomes more than a backdrop. It becomes a witness that sees without judging, that holds memories without needing to speak. The poem explores how the land can feel familiar in ways people sometimes can't, offering space to return to, again and again, even when you're not sure what you're …


Essays On Freedom And Power, John Acton Jul 2025

Essays On Freedom And Power, John Acton

Hannah Arendt Marginalia - All

New York : [Published by Noonday Press], 1955, [c1948]

Call #: New York : JC571 .A14 1955

Excerpted pages contains marginalia, underlining and marginal lining

PDF Information: 77 pages – 4.5 MB


Tank Chair [Book Review], Jj Pionke Jul 2025

Tank Chair [Book Review], Jj Pionke

Disability in LIS (DisLIS)

We are introduced to Nagi our wheelchair using assassin, and his adorable younger sister, as they try to figure out how improve the amount of time where he is awake.


Effects Of Plasma-Activated Water On Wheat: Germination And Seedling Development, Wafaa Abdulrazzaq Abdullah, Hadeel O. Ismael, Duaa A. Uamran, Hammad R. Humud Jul 2025

Effects Of Plasma-Activated Water On Wheat: Germination And Seedling Development, Wafaa Abdulrazzaq Abdullah, Hadeel O. Ismael, Duaa A. Uamran, Hammad R. Humud

Karbala International Journal of Modern Science

The food sector must contend with issues such as pathogen resistance to some of the available chemical agents, environmental pollution, and climate change to provide healthy food for livestock and people. The application of atmospheric pressure plasma jets (APPJs) is one potential solution for such problems. Plasma is appropriate for effective surface decontamination regarding food products and seeds, surface decontamination, and achieving improved agricultural production yields. The impact of plasma-activated water (PAW) produced by plasma jet discharge (PJD) system on in vitro-cultivated wheat seeds is examined in this work. For this aim, a plasma jet system was constructed with a …


Novel Suclg1 Variants In A Patient With Fatal Neonatal Onset Succinyl-Coa Ligase Deficiency, Devlynne S. Ondusko, Lauren Culbertson, Cary O. Harding, Cori Feist, Johan L.K. Van Hove, Marisa W. Friederich, Sacha Ferdinandusse, Roxanne A. Van Hove, Jonathan N. Pruneda, Brian Scottoline, Kimberly A. Kripps Jul 2025

Novel Suclg1 Variants In A Patient With Fatal Neonatal Onset Succinyl-Coa Ligase Deficiency, Devlynne S. Ondusko, Lauren Culbertson, Cary O. Harding, Cori Feist, Johan L.K. Van Hove, Marisa W. Friederich, Sacha Ferdinandusse, Roxanne A. Van Hove, Jonathan N. Pruneda, Brian Scottoline, Kimberly A. Kripps

Journal of Pediatric Genetics

Succinyl-CoA ligase deficiency is a rare autosomal recessive enzymatic deficiency that causes an energy-deficient state with mitochondrial depletion syndrome. It is often fatal. We present a case of novel variants in SUCLG1 leading to fatal infantile lactic acidosis. Two variants of uncertain significance in trans were identified in SUCLG1: c.901G>A p.(Gly301Arg) paternally inherited and c.532-6T>A maternally inherited. These variants resulted in severely reduced succinyl-CoA ligase activity. This patient exhibited the classical metabolic profile of succinyl-Co-A ligase deficiency and massive elevation of glutamine. Elevated glutamine, in the absence of hyperammonemia, should lead providers to consider succinyl-CoA ligase deficiency in …


46,Xx Disorders Of Sex Development: A Case With P.Arg92trp Variant In Nr5a1, Mehmet Ali Oktay, Agah Akin, Esra Döğer, Gülsüm Kayhan, Gizem Eşme Kocaman, Mahmut Orhun Çamurdan, Aysun Bi̇deci̇ Jul 2025

46,Xx Disorders Of Sex Development: A Case With P.Arg92trp Variant In Nr5a1, Mehmet Ali Oktay, Agah Akin, Esra Döğer, Gülsüm Kayhan, Gizem Eşme Kocaman, Mahmut Orhun Çamurdan, Aysun Bi̇deci̇

Journal of Pediatric Genetics

Ovotesticular (OT) disorders of sex development (DSDs) are marked by the simultaneous presence of ovarian and testicular tissues within the gonads. The appearance of external genitalia does not necessarily correlate with gonadal histology. Variants in the NR5A1 gene can result in SRY-negative DSD. In this report, we present a case involving a variant in the NR5A1 gene. A 3-year-old phenotypic male presenting with micropenis, penile hypospadias, and a bifid scrotum was identified to have a c.274C > T, p.Arg92Trp variant in the NR5A1 gene, along with a 46, XX karyotype. Genetic factors such as variants in the NR5A1 gene, independent of …


A New Case Of Kilquist’S Syndrome With A Novel Variant In Slc12a2 And A Brief Review Of The Literature, Hatice Yelda Yalçin, Yiğithan Güzin, Tayfun Cinletil, Berk Özyilmaz, Gamze Uzan, Melis Köse, Figen Baydan Jul 2025

A New Case Of Kilquist’S Syndrome With A Novel Variant In Slc12a2 And A Brief Review Of The Literature, Hatice Yelda Yalçin, Yiğithan Güzin, Tayfun Cinletil, Berk Özyilmaz, Gamze Uzan, Melis Köse, Figen Baydan

Journal of Pediatric Genetics

Background: Kilquist syndrome (KILQS) is a recently characterized, rare disorder characterized by hearing loss, secretory dysfunction, gastrointestinal system (GIS) abnormalities, and neurological anomalies including hypotonia and global developmental delay. It is caused by variants in the SLC12A2 (Solute Carrier Family 12 Member 2) gene which encodes the Na-K-2Cl cotransporter isoform 1 (NKCC1). Objective: This study aims to contribute to genotype-phenotype correlations for SLC12A2 variants. Material and Methods: We evaluated a Turkish patient with a novel variant in SLC12A2 gene and reviewed all previously reported cases with Kilquist syndrome. Whole exome sequencing and Sanger sequencing were used as molecular genetic testing …


Egfr Mutation In Neonatal Nephrocutaneous Syndrome: Unveiling A Genetic Challenge, Manuela S. Lopes, Cátia Martins, Ana Ferraz, Joana Rosmaninho-Salgado, Rui Castelo, Joaquim Tiago, Leonor Ramos Jul 2025

Egfr Mutation In Neonatal Nephrocutaneous Syndrome: Unveiling A Genetic Challenge, Manuela S. Lopes, Cátia Martins, Ana Ferraz, Joana Rosmaninho-Salgado, Rui Castelo, Joaquim Tiago, Leonor Ramos

Journal of Pediatric Genetics

Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein that exhibits tyrosine kinase signaling activity, playing a pivotal role in various cellular processes. Overexpression or overactivity of EGFR is significantly associated with inflammatory and malignant diseases, particularly lung cancer. Conversely, germline loss-of-function mutations in EGFR have been distinctly linked to a rare condition known as neonatal nephrocutaneous syndrome. We report a case of a preterm female neonate, born to consanguineous parents and from a pregnancy that was complicated by polyhydramnios. From birth, she displayed distinctive clinical features, including fragile skin and widespread erythema, sparse scalp hair, bilateral ankyloblepharon, thick eyebrows, …


A Child With Non-Growth Hormone-Deficient Short Stature With Chromosome 2 Deletion Of 2q35-36.1: A Case Report And Literature Review Of Haploinsufficiency Of Epha4 Gene, Jun Sun, Ya Xiao, Shu-Qin Jiang, Yi-Fan Wang, Hong-Ru Zhang, Wei Wang Jul 2025

A Child With Non-Growth Hormone-Deficient Short Stature With Chromosome 2 Deletion Of 2q35-36.1: A Case Report And Literature Review Of Haploinsufficiency Of Epha4 Gene, Jun Sun, Ya Xiao, Shu-Qin Jiang, Yi-Fan Wang, Hong-Ru Zhang, Wei Wang

Journal of Pediatric Genetics

Non-growth hormone-deficient short stature is a group of growth developmental disorders with complex pathophysiological mechanisms involving multiple pathways, including abnormalities in the growth hormone/insulin-like growth factor 1 signal pathway. We report a 4-year-old girl with severe growth and developmental delay: her height was 91 cm (<–3 standard deviation [SD]), and her growth rate was 3 to 4 cm/year (<–2 SD). Growth hormone stimulation tests indicated a normal peak growth hormone level (11.1 μg/L), while insulin-like growth factor-1 levels were reduced (7.98 nmol/L, <–1SD). Whole exome sequencing and copy number variation analysis revealed a 3.19 Mb deletion at 2q35-q36.1 on chromosome 2, encompassing all coding regions of the Epha4 gene. This study suggests an association between Epha4 gene deletion and non-growth hormone-deficient short stature, highlighting the importance of further research on this gene and its related signaling pathways to understand the molecular mechanisms of the disease and potential therapeutic approaches.


The First Turkish Spondylocarpotarsal Synostosis Syndrome Case With Ventricular Septal Defect And Pelvicaliectasia Caused By A Novel Homozygous Frameshift Variation In Flnb, Esra Dirimtekin, Esra Arslan Ateş, Hamza Polat, Eda Almus, Bilgen B. Geckinli Jul 2025

The First Turkish Spondylocarpotarsal Synostosis Syndrome Case With Ventricular Septal Defect And Pelvicaliectasia Caused By A Novel Homozygous Frameshift Variation In Flnb, Esra Dirimtekin, Esra Arslan Ateş, Hamza Polat, Eda Almus, Bilgen B. Geckinli

Journal of Pediatric Genetics

Spondylocarpotarsal synostosis syndrome (SCT) (OMIM: 272460) is an autosomal recessive disorder characterized by block vertebrae, carpal-tarsal synostosis and disproportionate short stature. Some clinical characteristics of SCT are dysmorphic facial traits, cleft palate, hypoplastic tooth enamel, brachydactyly, clinodactyly, limited joint movement and mixed hearing loss. Biallelic nonsense and frameshift pathogenic variantions in FLNB gene are associated with SCT. An 8 -year -old patient was referred with a suspicion of skeletal dysplasia. He had short stature, scoliosis, carpal-tarsal synostosis and ventricular septal defect (VSD). Clinical exome sequence (CES) analysis was performed and a novel homozygous frameshift variation in FLNB (c.219_222dup p.Met75Profs*17) was …


Systematic Review About Clinical And Radiologic Manifestations In Patients With Fatco Syndrome, D’Karlo Yosue Dongo Cornejo, Wendy Alessandra Gutiérrez Baca, Maria Cristina Laso Salazar, Hugo Hernán Abarca-Barriga Jul 2025

Systematic Review About Clinical And Radiologic Manifestations In Patients With Fatco Syndrome, D’Karlo Yosue Dongo Cornejo, Wendy Alessandra Gutiérrez Baca, Maria Cristina Laso Salazar, Hugo Hernán Abarca-Barriga

Journal of Pediatric Genetics

FATCO syndrome (Fibular Aplasia, Tibial Camptomelia, Oligosyndactyly) is characterized by the presence of Fibula Aplasia, Tibial Campomelia and Oligosyndactyly. It is an autosomal dominant congenital genetic disorder, with an infrequent occurrence. This is the main reason behind the limited number of studies carried out to date, and the importance of carrying out this review to enhance the understanding of this syndrome. The objective of this review based on case reports is to describe and analyze the clinical and radiological characteristics of patients diagnosed with FATCO syndrome, in addition to demographic characteristics and concomitant anomalies. The databases used in this review …


Genotype First Approach As A Diagnostic Strategy For Precision Medicine In Moroccan Families With Nephronophthisis, Ourayna Batta, Imane J. Cherkaoui, Yasmina Rahmuni, Nada Amllal, Kenza Soulami, Abdelaziz Sefiani, Jaber Lyahyai Jul 2025

Genotype First Approach As A Diagnostic Strategy For Precision Medicine In Moroccan Families With Nephronophthisis, Ourayna Batta, Imane J. Cherkaoui, Yasmina Rahmuni, Nada Amllal, Kenza Soulami, Abdelaziz Sefiani, Jaber Lyahyai

Journal of Pediatric Genetics

Nephronophthisis is a group of autosomal recessive kidney diseases characterized by chronic tubulointerstitial abnormalities leading to kidney failure. The incidence of nephronophthisis varies globally, and its genetic heterogeneity presents significant difficulties in diagnosis. Herein, we present a molecular diagnosis of four unrelated Moroccan families fulfilling the clinical criteria of nephronophthisis. As first diagnosis step, screening for a homozygous NPHP1 gene deletion, the most common mutation, was performed by using multiplex polymerase chain reaction. Additionally, clinical exome sequencing was carried out on patients in whom no NPHP1 deletion was identified. Three novel pathogenic variants in NPHP1, INVS, and NPHP4 genes were …


Sleep Disordered Breathing In Children With Achondroplasia: 17 Years’ Experience From A Multidisciplinary Team, Maria Jose Guerdile, Virginia Fan, Mariana Del Pino, Vivian Leske Jul 2025

Sleep Disordered Breathing In Children With Achondroplasia: 17 Years’ Experience From A Multidisciplinary Team, Maria Jose Guerdile, Virginia Fan, Mariana Del Pino, Vivian Leske

Journal of Pediatric Genetics

The aim of this study was to describe sleep-disordered breathing (SDB) and treatment in children with achondroplasia (ACH). A retrospective longitudinal study was conducted at the Sleep Unit, Hospital de Pediatría Garrahan. Children with ACH, aged 0 to 18 years, referred for SDB due to clinical symptoms or foramen magnum stenosis (FMS) with at least one polysomnography (PSG) between 2002 and 2019 were included in the study. The primary outcomes included SDB typification and therapeutic interventions. We included 89 patients; 79.7% had one PSG, 13.4% had two PSGs, and 5.6% had three PSGs. The first PSG confirmed SDB in 65.16% …


Mucolipidosis Iii Gamma Masquerading As Juvenile Idiopathic Arthritis, Vykuntaraju K. Gowda, Sharath Babu, Varunvenkat M. Srinivasan Jul 2025

Mucolipidosis Iii Gamma Masquerading As Juvenile Idiopathic Arthritis, Vykuntaraju K. Gowda, Sharath Babu, Varunvenkat M. Srinivasan

Journal of Pediatric Genetics

No abstract provided.


Opportunities For Growth: A Metacognitive Self-Talk Strategy That Improves Classroom Unity And Academic Attitudes, Sera Anello, Michael J. Haslip Jul 2025

Opportunities For Growth: A Metacognitive Self-Talk Strategy That Improves Classroom Unity And Academic Attitudes, Sera Anello, Michael J. Haslip

Journal of Practitioner Research

This teacher action research study describes the development and application of the opportunities for growth teaching method to increase learner motivation, persistence, cooperation and positive self-talk among primary school students. The approach was implemented with 30 fourth graders in a Philadelphia public school classroom to foster unity, support attitudes toward academics and participation, redefine failure, and reframe challenges. Before this intervention, most of the students lacked self-regulation, self-awareness, and relationship skills needed to thrive. This study investigates how and to what effect the opportunities for growth approach shifts students’ language and mindset about academic and social challenges. Qualitative data was …


Teacher Inquiry: How Mathematics Discourse And Hands-On Learning Impact Student Outcomes And Teacher Attitudes, Mary-Katherine Miller Jul 2025

Teacher Inquiry: How Mathematics Discourse And Hands-On Learning Impact Student Outcomes And Teacher Attitudes, Mary-Katherine Miller

Journal of Practitioner Research

In this inquiry, the teacher worked alongside a university mentor to develop, monitor, and analyze the teacher’s wonderings. In a 3rd grade classroom, the teacher wanted to explore how hands-on and discourse strategies could impact mathematics achievement for all students. Specifically, the teacher explored how utilizing hands-on activities and discourse strategies in collaborative groups could lead to increased engagement and better outcomes for her exceptional student education (ESE) population in learning multiplication and division. Throughout the inquiry, the teacher used checklists, anecdotal notes, and student exit ticket scores to monitor student progress. At the end of the inquiry cycle, the …


Teaching Ai Ethics And Skepticism: The Impact Of Instruction On Ethical Usage On Students’ Perceptions, Jenna D. Justin Jul 2025

Teaching Ai Ethics And Skepticism: The Impact Of Instruction On Ethical Usage On Students’ Perceptions, Jenna D. Justin

Journal of Practitioner Research

This study investigates the ethical implications of artificial intelligence (AI) in K-12 education, focusing on how explicit instruction influences students' perceptions of AI tools like ChatGPT. Conducted with 80 sixth-grade students at A.D. Henderson University School and FAU High School, the research tracks changes in student understanding and skepticism of AI following a World History unit. Pre- and post-instruction surveys revealed a decline in comfort with AI as students became more aware of its ethical concerns, including plagiarism, bias, and misinformation. The findings suggest integrating AI ethics into the middle school curriculum to foster responsible AI usage among students.