Digital Commons Network^™

2018-10-30 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2017-08-22 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2019-03-19 Leadership Council Minutes, Dianne Pipes

Executive Council Minutes

No abstract provided.

2017-06-14 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2018-03-20 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2018-05-01 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2016-08-16 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2016-09-13 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2017-12-13 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2016-11-29 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2015-08-04 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2015-08-25 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2015-08-31 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2015-10-27 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2015-09-08 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2016-01-19 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

Mainers Overwhelmingly Favor Release Of All Epstein Files, Oppose Maxwell Clemency 8/22/2025, Unh Survey Center

All UNH Survey Center Polls

Nearly all Maine residents want the Department of Justice to release all documents it has related to the Jeffrey Epstein investigation. Majorities believe both the Trump and Biden administration have concealed evidence in the case and believe Trump and former President Bill Clinton were involved in crimes related to the case. Three-quarters oppose clemency for Epstein accomplice Ghisliane Maxwell. A majority of Mainers continue to disapprove of President Trump's job performance thus far.

Ectopic Adipose Tissue In Subsistence Populations With Minimal Coronary Disease, Large Left Atria, And Very Low Rates Of Atrial Fibrillation, Randall C. Thompson, Benjamin C. Trumble, Daniel K. Cummings, Angela D. Neunuebel, Paul L. Hooper, Samuel Wann, Adel H. Allam, Frances Neunuebel, Benjamin D. Gans, Samantha I. King, Edmond Seabright, Caleb E. Finch, Margaret Gatz, Kenneth Buetow, Michael I. Miyamoto, Guido P. Lombardi, M. Linda Sutherland, James D. Sutherland, Christopher J. Ward, Madeleine J. Lee, Ashna Mahadev, Daniel Eid Rodriguez, David E. Michalik, Chris J. Rowan, Tianyu Cao, Jonathan Stieglitz, Cameron M. Quick, Gregory S. Thomas, Jagat Narula, Damini Dey, Michael Gurven, Hillard Kaplan

ESI Publications

Background

Methods

Nyls’S 2025 Orientation: Building Community And Embracing Civic Leadership, Jennifer Bancamper

NYLS Community News

No abstract provided.

Enteric/Typhoid Fever In A Returning Traveler: An Approach To A Thorough Medical Workup, Matthew Meyer, John Rogers, Rick Starlin

Medical Student Research Showcase

Up to 70% of travelers to low-income regions experience health complications, most of which are self-limiting. However, 8% to 15% require medical evaluation either during travel or upon return, with fever frequently reported as a primary symptom.1 As such, the importance of a thorough medical workup in a returning traveler with fever cannot be overstated, as it may be the first sign of a potentially serious or infectious disease acquired abroad. High risk pathogens to be concerned for include Malaria, Dengue, Chikungunya, Leptospiral, typhoid, and others, and thus it is incredibly important to narrow your differential, which will guide your …

How To Study 30-Day Readmissions: A Framework For Risk Stratification And Methodological Rigor, Mckenna Gervais, Kayley Anderson, Jana Wardian, Jayme Dowdall

Medical Student Research Showcase

Background: The 2010 Affordable Care Act (ACA) catalyzed a shift toward value-based care. This introduced reimbursement penalties tied to hospital performance metrics, such as the Hospital Readmission Reduction Program (HRRP) which deducts reimbursement for institutions with excessive 30-day readmission rates. Although more than 25% of hospital readmissions are considered potentially avoidable, the methods of evaluation are often inconsistent, and overlook medically complex patients and those who experience recurrent readmissions.

Objective: To identify methodologies used in current 30-day readmission studies and to propose improved methodological framework for population inclusion, demographic considerations, and statistical analysis to allow for proper risk stratification.

Methods: …

A 6-Month, Prospective Randomized Controlled Trial Of The Targeted Management (Team) Intervention Vs. Enhanced Treatment As Usual Among Ugandans At Risk For Stroke, Carla Conroy, Joy Yala, Christopher J. Burant, Shirley Moore, Martha Sajatovic

Faculty Scholarship

Background Among low and middle-income countries, especially in Sub-Saharan Africa, the stroke burden is severe, with increasing trends in stroke incidence, prevalence, and mortality. Aims This 6-month, prospective randomized controlled trial (RCT) compared a novel stroke risk reduction approach (TargetEd manAgeMent Intervention (TEAM)) vs. Enhanced Treatment as Usual (ETAU) in 247 Ugandans at risk for stroke. Methods Participants, enrolled across 3 Ugandan sites, were adults with high stroke risk. The primary outcome was a change in systolic blood pressure (SBP) from baseline to 6-month follow-up. Secondary outcomes included changes from baseline to 6 months on diastolic BP (DBP), serum lipids, …

Exposure-Inducible Genes May Contribute To Missingness In Rnaseq-Based Gene Expression Analyses, Olga Y Gorlova, Ivan P Gorlov, R Taylor Ripley, Chao Cheng, Yafang Li, Bo Peng, Yanhong Liu, Hee-Jin Jang, Sung Wook Kang, Claire Lee, Priyanka Ranchod, Bryan M Burt, Hyun-Sung Lee, Christopher I Amos

Faculty, Staff and Students Publications

Missing gene expression values are a common issue in RNAseq-based analyses of gene expression. However, an analysis of genetic and environmental factors contributing to data missingness in RNAseq-based assessment of gene expression has never been conducted. In this study we tried to identify factors in RNAseq data missingness. We used RNAseq data from 66 lung adenocarcinoma tumors and corresponding adjacent normal lung tissues. We found a strong negative association between the gene expression level and missingness, supporting the idea that the borderline expression level is a key contributor to missingness. In a more detailed analysis, the relationship between gene expression …

Prolonging Lung Cancer Response To Egfr Inhibition By Targeting The Selective Advantage Of Resistant Cells, Lisa Brunet, David Alexandre, Jiyoung Lee, Maria Del Mar Blanquer-Rosselló, David Bracquemond, Alexis Guernet, Houssein Chhouri, Mathilde Goupil, Zoulika Kherrouche, Arnaud Arabo, Maicol Mancini, Dorthe Cartier, Shen Yao, David Godefroy, Julie Dehedin, Jian-Rong Li, Céline Duparc, Philippe Jamme, Audrey Vinchent, Caroline Bérard, David Tulasne, Sabrina Arena, Alberto Bardelli, Chao Cheng, Byoung Chul Cho, Olivier Wurtz, Cédric Coulouarn, Antonio Maraver, Stuart A Aaronson, Alexis B Cortot, Youssef Anouar, Luca Grumolato

Faculty, Staff and Students Publications

Non-small cell lung cancers (NSCLCs) treated with tyrosine kinase inhibitors (TKIs) of the epidermal growth factor receptor (EGFR) almost invariably relapse in the long term, due to the emergence of subpopulations of resistant cells. Through a DNA barcoding approach, we show that the clinically approved drug sorafenib specifically abolishes the selective advantage of EGFR-TKI-resistant cells, while preserving the response of EGFR-TKI-sensitive cells. Sorafenib is active against multiple mechanisms of resistance/tolerance to EGFR-TKIs and its effects depend on early inhibition of MAPK-interacting kinase (MKNK) activity and signal transducer and activator of transcription 3 (STAT3) phosphorylation, and later down-regulation of MCL1 and …

2018-09-12 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2018-11-06 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2016-09-27 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2016-10-04 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2015-10-13 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2015-11-17 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.