Digital Commons Network^™

Predicting Regional Cerebral Blood Flow Using Voxel-Wise Resting-State Functional Mri, Hongjie Ke, Bhim M Adhikari, Yezhi Pan, David B Keator, Daniel Amen, Si Gao, Yizhou Ma, Paul M Thompson, Neda Jahanshad, Jessica A Turner, Theo G M Van Erp, Mohammed R Milad, Jair C Soares, Vince D Calhoun, Juergen Dukart, L Elliot Hong, Tianzhou Ma, Peter Kochunov

Faculty, Staff and Student Publications

Background: Regional cerebral blood flow (rCBF) is a putative biomarker for neuropsychiatric disorders, including major depressive disorder (MDD).

Methods: Here, we show that rCBF can be predicted from resting-state functional MRI (rsfMRI) at the voxel level while correcting for partial volume averaging (PVA) artifacts. Cortical patterns of MDD-related CBF differences decoded from rsfMRI using a PVA-corrected approach showed excellent agreement with CBF measured using single-photon emission computed tomography (SPECT) and arterial spin labeling (ASL). A support vector machine algorithm was trained to decode cortical voxel-wise CBF from temporal and power-spectral features of voxel-level rsfMRI time series while accounting for PVA. …

Examining Barriers To Crisis Service Use Among Black Young Adults, Emily K. Burns

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Black communities face an increased burden of mental illness (Gordon, 2020). This can be linked to factors such as experiences of racism, higher rates of unemployment, financial and food insecurity, and disparities in health care (Gordon, 2020). Despite this, Black communities have historically experienced relatively low rates of suicide (Gordon, 2020). This has been anecdotally attributed to protective cultural values and beliefs about suicide. However, there has been a recent shift in this trend, particularly for Black youth and young adults.

The Journey Of Psychotherapy: Understanding Therapeutic Technique Through Ultralight Thru Hiking, Emma Bossier

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

This paper explores several principles of ultralight backpacking as metaphors for developing one’s therapeutic technique. The tenets of ultralight thru hiking, when interpreted through a clinical lens, offer early clinicians insight into the importance of moving through fear and leaning into exploration, discomfort, and authenticity while on the journey of becoming a therapist. The experiences of numerous thru hikers are synthesized into five principles: Don’t Pack Your Fears, Be Present for the Journey, Slow Simplicity, Embrace the Suck (and The Stink), and Trail Legs. These principles do not define ultralight as carefreeness but rather offer a metaphor for the careful …

Playing Catch Up: A Brief Look Into Modern Internet Culture And Its Impact On Adolescent Male Development, Xavier Bird

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

This doctoral paper argues that the internet, particularly the "manosphere," poses three significant threats to the development of adolescent males in the U.S.: the influence of misogynistic online personalities, the normalization of risky online behavior, and the spread of right-wing misinformation. The paper highlights the role of the COVID-19 pandemic in exacerbating these issues due to increased internet usage. Furthermore, it proposes a research study to investigate the link between exposure to online misogynistic content and aggressive behavior in schools, emphasizing the unique challenges of studying adolescents and their online culture. Finally, the paper stresses the urgent need for updated …

The Developmental Cohort Model Of Interpersonal Process Groups: A Clinician's Guide For University Counseling Centers, Lauren Caldas

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

The purpose of this paper is to outline a clinician's manual that guides providers in the development, facilitation, and maintenance of long-term interpersonal process groups (IPGs) within university counseling centers (UCCs). This manual also presents a new model: The Developmental Cohort Model (DCM), which utilizes a stepped model throughout a traditional student's college timeline. I will present this manual in the context of the Developmental Cohort Model (DCM), but it can certainly remain useful for any type of IPG. Research suggests that group therapy is an effective way to increase access to mental health care (Burlingame & Strauss, 2021) and …

A Clinical Pathway For Differential Diagnosis Of Adhd Vs Trauma: Early Childhood Recognition And Intervention, Maria Neiers

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Distinguishing Attention-Deficit/Hyperactivity Disorder (ADHD) from Complex Posttraumatic Stress Disorder (C-PTSD) presents significant diagnostic challenges due to overlapping symptom presentations, shared neurobiological impacts, and frequent comorbidities. This paper explores the nuanced clinical differentiation between ADHD and C-PTSD, and other trauma disorders, in pediatric populations, emphasizing the importance of trauma-informed assessment, early identification, and integrative clinical reasoning. The discussion highlights how structured diagnostic reasoning can reduce uncertainty, enhance diagnostic clarity, and support effective treatment planning. As a central contribution, this paper introduces an original clinical reasoning flowchart and a case conceptualization to illustrate its practical application in real-world diagnostic dilemmas. The need …

Applying Contextual Behavioral Science To Address Addictions In Monsters, Chase Hollander

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

The dominant essentialist paradigm in addiction treatment often conceptualizes addiction as a curse or plague which seizes the individual afflicted by it. Such views are reinforced by neurobiological interventions like Medication-Assisted Treatment (MAT). While MAT can reduce cravings and withdrawal symptoms, its long-term efficacy is mixed, and its emphasis on abstinence as a primary outcome limits its scope. Addiction is a multifaceted phenomenon shaped by physiological, psychological, social, and systemic factors—including stigma, moral judgment, and structural oppression. Essentialist approaches frequently pathologize individuals and obscure these broader influences. In contrast, contextual behavioral sciences and therapies aligned with functional contextualism such as …

Proposed Theoretical Model Of Pediatric Onset Multiple Sclerosis And Restrictive Eating Behaviors, Anna L. Smith

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Multiple Sclerosis (MS), a chronic, demyelinating, autoimmune disease that causes an array of physical and cognitive symptomatology, is commonly diagnosed in adulthood. Pediatric Onset Multiple Sclerosis (POMS) is characterized by diagnosis of the disease before age 18 and accounts for about 5% of MS cases. While there is a growing body of literature examining the impact of adult-onset multiple sclerosis on psychosocial functioning, research specifically addressing POMS remains limited. Moreover, there is a notable gap in the literature regarding the risk of eating disorders among individuals with POMS. This paper will explore a constellation of potential risk factors that may …

Supporting Healthy Siblings In Pediatric Cancer: Advancing Relational Interventions To Heal Invisible Wounds, Kristen K. Wederski

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Healthy siblings of children diagnosed with cancer occupy a uniquely vulnerable position within the pediatric oncology landscape. Individuals within this population often demonstrate significant emotional distress and can experience long-term psychological challenges. Despite their risk, healthy siblings remain under-researched and under-supported compared to pediatric patients and caregivers. Existing interventions tend to prioritize individual coping skills and psychoeducation and often overlook the critical relational dynamics that shape healthy siblings' psychological adjustment. Grounded in systematic and relational theories, this paper proposes a paradigm shift toward relationally focused interventions that strengthen the caregiver-sibling bond as a core mechanism of change to foster resilience …

Mrs. Katie Mosley

African American Funeral Programs

No abstract provided.

Prolonged Exposure To Food Odors Suppresses Feeding Via An Olfactory Bulb-To-Hypothalamus Circuit, Yao Liu, Hailan Liu, Huey-Xian Kelly Wong, Niccole Auld, Kristine M Conde, Yongxiang Li, Meng Yu, Yue Deng, Qingzhuo Liu, Xing Fang, Mengjie Wang, Yuhan Shi, Olivia Z Ginnard, Yuxue Yang, Longlong Tu, Hesong Liu, Jonathan C Bean, Junying Han, Megan E Burt, Sanika V Jossy, Yongjie Yang, Chunmei Wang, Qingchun Tong, Benjamin R Arenkiel, Hongjie Li, Yong Xu, Yang He

The Brown Foundation: Institute of Molecular Medicine

Olfactory perception of food odors is a key determinant of eating behavior, including triggering appetite, facilitating food seeking and influencing food choice. While transient food-related olfactory cues stimulate appetite and provoke cravings in states of hunger, emerging evidence implies that prolonged and sustained exposure to food-derived odor (FO) suppresses feeding. However, the mechanisms by which olfaction induces hypophagia remain elusive. In this study, we show that prolonged FO exposure significantly suppresses food intake in male mice. We identified a subset of neurons in the ventral subiculum (vSub) that are specifically activated by FO. We further discovered that these FO-activated neurons …

Review Of Human Papillomavirus Vaccination Programs In United States Schools, Cassandra Duran, Aditi Gupta, Lynda Aririguzo, Norma Castillo, Sanghamitra M Misra

Faculty, Staff and Students Publications

Background: School vaccination programs (school-based and school-located) that include the human papillomavirus (HPV) vaccine have been implemented throughout the United States since 2009.

Methods: We conducted a review of school HPV vaccination programs in PUBMED, Google Scholar, Web of Science, Ovid, Medline, and Embase and included peer-reviewed studies originating in the United States that focused on any aspect of HPV school vaccination programs.

Results: Our review yielded 47 articles that fell into several categories: (1) parent and child perceptions, (2) school nurse perceptions, (3) development, (4) implementation, (5) outcomes, and (6) barriers and facilitators of HPV vaccination programs in schools. …

Targeting Sting To Disrupt Macrophage-Mediated Adhesion In Encapsulating Peritoneal Sclerosis, Juan Sun, Yuxiang Sun, Dandan Guo, Huolin Ye, Qiang Huang, Hu Zhou, Canming Li, Mei Liao, Yujia You, Hongli Shang, Pan Zhou, Dongxuan Wu, Janusz Witowski, Zhaoyong Hu, Hui Peng

Faculty, Staff and Students Publications

Encapsulating peritoneal sclerosis (EPS) is a life-threatening fibrotic condition characterized by severe abdominal adhesions, chronic inflammation, and significant morbidity. The lack of effective treatments for EPS stems from a limited understanding of its underlying mechanisms. In this study, we developed a modified mouse model of PD-induced EPS and investigated the role of the STING signaling pathway in disease progression. Our findings reveal that STING activation in peritoneal mesothelial cells significantly increases the secretion of the macrophage chemokine CCL2, leading to enhanced macrophage infiltration and the formation of pathological adhesions. Notably, pharmacological inhibition of STING using the inhibitor H151 effectively reduced …

Placental Polycyclic Aromatic Hydrocarbon (Pah) Levels Are Associated With Spontaneous Preterm Birth, Gwendolynn Hummel, Sohini Banerjee, Vasanta Putluri, Inaara Malick, Grace Johnson, Abu Hena Mostafa Kamal, Chandra Shekar R Ambati, Nagireddy Putluri, Lori Showalter, Cynthia D Shope, Joseph Hagan, Kjersti M Aagaard, Bhagavatula Moorthy, Melissa A Suter

Faculty, Staff and Students Publications

While the cause of preterm birth (PTB) (i.e., delivery before 37 weeks of gestation) is likely multifactorial, ambient exposure to environmental chemicals has been postulated to play a role in its etiology. Our prior studies of exposure to polycyclic aromatic hydrocarbons (PAHs) in pregnancy have shown an increased level of placental PAH-induced bulky DNA adducts with increasing levels of PAH exposures. In this investigation, we hypothesized that higher levels of placental PAHs would be associated with an increased risk of PTB. Using gas chromatography and mass spectrometry (GC-MS/MS), we measured levels of benzo(a)pyrene (BaP), benzo(b)fluoranthene (BbF) and dibenz(a,h)anthracene (DBA) from …

Dendritic Cell Neurofibroma With Pseudorosettes: A Case Report, Nabiha T. Atiquzzaman, Fahad S. Siddiqui, Sadia Saeed, Jacqueline Russo, Patrick Dominguez

GME Publications

Dendritic cell neurofibroma with pseudorosettes (DCNP) is an exceedingly rare neurofibroma variant presenting as scattered, isolated, skin-colored papules or nodules primarily on the trunk. It consists of clusters of smaller type I cells with dark nuclei and inconspicuous cytoplasm, surrounded by much larger type II cells with abundant cytoplasm and vesicular nuclei containing pseudoinclusions, resulting in the formation of distinctive pseudorosettes. While unique, it can be misdiagnosed as other neural tumors due to its histologic and clinical similarities. This report presents a unique case of DCNP in a 34-year-old male with a longstanding, asymptomatic 1.3 cm pink nodule on his …

Sars-Cov-2 Antibody Responses In Children Exhibit Higher Fcr Engagement And Avidity Than In Adults, Carolyn A Cohen, Ludivine Grzelak, Susan S Chiu, David Sc Hui, Mike Yw Kwan, Owen Ty Tsang, Wai Hung Chan, Yat Sun Yau, Kelly Wk Lee, Masashi Mori, Gaya K Amarasinghe, Samuel Ms Cheng, Leo Lm Poon, Malik Peiris, Sophie A Valkenburg

2020-Current year OA Pubs

As intrinsic differences in humoral immune response to SARS-CoV-2 between children and adults remain unclear, we improved characterisation by defining the kinetics, specificity and function of antibodies to SARS-CoV-2 in children (n = 146, aged 9.4 ± 4.8 years with n = 257 samples) compared to adults (n = 85, aged 39.5 ± 15.2 years with n = 122 samples). We used plasma samples from an infection and vaccination-naive cohort study with RT-PCR confirmed ancestral B.1* SARS-CoV-2 virus infection with asymptomatic or mild disease, collected in Hong Kong between March to December 2020, from acute (0-14 days post infection) to …

Exhibiting Rural Consciousness: A Study Of State And Local Level Governance In Rural Higher Education, Steven J. Skadron

Electronic Theses and Dissertations

Evolving economies in Craig and Salida, CO, spurred community interest in joining Colorado Mountain College’s taxing district and bringing the college to their communities. When they sought to join, Craig had a local college embedded in its community that was governed by a state-level board; in contrast, Salida had no local college of its own. The two communities’ pursuit of a locally governed college raised a question about governing boards and whether one type of governing board might serve rural communities better. Using a framework of rural consciousness, this nonexperimental, cross-sectional, quantitative study employed data gathered from a survey instrument …

The Shift: Embracing Loving Kindness And Nurse Well-Being As A Standard Of Care, Margaret Mcgrath Brown, Jennifer Rodriguez

Creating Healthy Work Environments (CHWE)

In response to mounting evidence of clinician burnout, the US Surgeon General declared a call to action, “we need to build a culture that supports well-being. It’s time to break the traditional silence surrounding the suffering of health workers”[1]. Our clinicians’ suffering in survival mode was confirmed by the findings from participation in a 2021 multi-site study among 60 Magnet hospitals evaluating clinician wellbeing[2].

Our organization embarked on a top-down/bottom-up approach rooted in loving kindness and personal and professional development. Over time, a shift has occurred, and an intentional transformation began towards viewing nurse well-being as a standard of care. …

Building A High-Performing Critical Care Outreach Team: Transforming Care And Collaboration, Heather Joy Cook, Brittany M. Wells

Creating Healthy Work Environments (CHWE)

The Critical Care Outreach Team (CCOT) at our large urban university medical center has become a cornerstone of patient safety and care, driving a significant cultural shift in rapid response and interdisciplinary collaboration from 2014 to 2024. Through the adoption of the six American Association of Critical Care Nurses (AACN) Healthy Work Environment standards, the CCOT has not only reduced cardiac arrests outside of critical care areas but also fostered a collaborative relationship based on trust, clinical excellence, and patient safety among ward staff that has transformed the culture of Rapid Response activations.

Clinical excellence has not been the only …

Introduction Of Code Lavender To Support The Well-Being Of Clinical Staff After Critical Events, Shannon Souther, Eunyoung Lee, Milena Staykova

Creating Healthy Work Environments (CHWE)

Debriefing after critical events can benefit individual healthcare workers and create a healthier work environment within the interdisciplinary team. The desire to participate in interdisciplinary debriefing (IDD) among healthcare workers has been expressed in previous studies. However, it may be difficult for workers to debrief without strong, hospital-wide support.

Purpose: A pilot study was conducted, intended to introduce and measure the feasibility of a new modality to deliver IDD, “Code Lavender.” The new process was aimed at addressing a known barrier to IDD by offering hospital support.

Methods/Implementation: IDD was implemented in 3 ICU settings over a 3-month period. Code …

Fostering Excellence Through Development Of A Code Stroke Response Nurse, Emma Bingham

Creating Healthy Work Environments (CHWE)

Situation: Toronto Western Hospital (TWH) is a Regional Stroke Centre, meaning that patients suspected of stroke bypass other centres to access TWH. This designation results in care for neurologically complex patients, requiring efficient stroke protocols and proficient, knowledgeable clinicians. Notification of a patient en-route to the Emergency Department with a suspected stroke sets off a cascade of events that require a streamlined, coordinated approach; a Code Stroke.

Background: There were many factors reinforcing the need to reevaluate TWH’s Code Stroke protocol, including the change to administration of tenecteplase for ischemic stroke, significant wait times and subsequent unsafe patient ratios in …

Growing Dreams: Enabling Rural High School Students' Healthcare Career Futures Via A Summer Camp, Minerva Gonzales, Adrian Billings, John Dijo, Katie Miller

Creating Healthy Work Environments (CHWE)

Rural health systems and hospitals are foundational to the health and economy of rural communities. Although rural healthcare organizations face multiple challenges, one of the most significant is recruitment and retention of the workforce. According to the American Hospital Association (2022), rural areas account for nearly 70% of Health Professional Shortage Areas (HPSAs). In addition, recruitment to a rural community can be difficult and retainment is even more challenging (Cosgrave et al., 2019). With these challenges in mind, an interdisciplinary and multi-institutional team collaborated to initiate a rural healthcare summer camp for rural high school students from the region at …

Work Safety Climate, Heat-Related Illness, And Pesticide Risks Among Latino Farmworker Adolescents, Fiorella L.Carlos Chavez, Priscilla Carmiol-Rodriguez, Taylor J. Arnold, Evan P. Anderson, Alexandra Brewis, Amber Wutich, Keenan A. Pituch, Scott C. Carvajal, Thomas A. Arcury, David W. Coon

Creating Healthy Work Environments (CHWE)

Among Latino farmworker adolescents (FWA), previous studies found that almost 50% reported HRI and symptoms while working in the fields and that being an older adolescent (compared to a younger one) increased the probability of reporting work-related injuries and HRI. Furthermore, Latino FWA often lack work experience, which could lead to unsafe occupational behaviors. Work safety climate (WSC) is the degree to which a worker perceives management values production over safety. Evidence suggests that weak WSC could lead farmworkers to engage in fewer safety procedures, increasing their risk of occupational injuries. Nevertheless, WSC research on HRI and pesticide risk (PR) …

Emergency Nurses’ Barriers To Caring For Psychiatric Boarders: A Theory Of Planned Behavior Approach, Rachel Keslar, Cindy Bacon

Creating Healthy Work Environments (CHWE)

In 2021 around 2.5 million patients sought psychiatric care through the emergency department.¹ However, emergency department based psychiatric care has challenges including overcrowded hectic environments ^2–5 and prevalent patient violence.^2,4,5 This includes the practice of boarding where medically cleared patients cannot be dispositioned due to inadequate non-emergency department services6 and wait in the emergency department for hours, days, or longer.⁷ This leads to negative patient effects including increased vulnerability,³ distress,⁵ and violence.⁸ The purpose of this presentation is to show how the Theory of Planned Behavior was used to identify practice barriers in caring …

Exploring Secondary Traumatic Stress: The Frontline Psychiatric Mental Health Nurses' Perspective, Stacy Horowitz

Creating Healthy Work Environments (CHWE)

Background: Research demonstrates that Psychiatric Mental Health Nurses (PMHNs) are affected by Secondary Traumatic Stress (STS). As many as 44% of PMHNs experience clinical levels of psychological distress and STS as compared to RNs in other specialties, including those in forensic nursing. Interventions that promote RN resilience are mentioned less frequently in this research.

Objectives: To explore frontline PMHNs’ perspective on STS and remaining safe and engaged at work on the inpatient behavioral health unit.

To solicit PMHNs’ input on helpful interventions to foster the development of "Universal Precautions" against STS.


Method: Eleven PMHNs participated in one of three focus …

Enhancing Resilience In Nursing Education Through The Lens Of Gratitude, Sarah B. Hathcock, Deanna B. Hiott, Carol K. Archuleta

Creating Healthy Work Environments (CHWE)

Resilience has consistently been identified as a hallmark characteristic among individuals who invest themselves in the workplace, while also finding meaningfulness and happiness in their work (Keener et al., 2021). Moreover, resilience is a protective health factor essential to an individual’s ability to negate the harmful effects of stress; it is a construct linked to improved mental and physical health (Asensio-Martínez et al., 2019). Nursing faculty, like all nurses, have the personal responsibility to ensure they are employing practices to foster and maintain their personal well-being, while also contributing to a healthy work environment. The Three Good Things gratitude practice …

Using Faculty And Staff Voice To Drive Workplace Well-Being Strategy, Angela G. Opsahl, Jennifer Louise Embree, Whitney Osborn

Creating Healthy Work Environments (CHWE)

The purpose of this presentation is to describe a faculty and staff wellbeing strategy in an academic setting.

Workplaces supporting wellbeing have employees three to nine times more likely to have good mental and physical health, little stress, no burnout, and high-quality work life, compared to workplaces providing little or no wellbeing support.

Academic leaders saw an opportunity to make a difference in faculty and staff wellbeing. Faculty and staff perspectives were identified through the MiniZ Survey General, and open-ended questions, and leaders developed wellbeing sessions and programs. The first session was a wellbeing workshop hosted just prior to an …

Making Fractals: Expanding Learning Opportunities In The Classroom, Eliza Leszczynski, Eileen Fernández, Elise Lahiere

LASER Journal

Fractals have long been appreciated for their beautiful, self-similar structure and infinite complexity. Commonly found in art and architecture, fractals are not only visually appealing but they have been found to reduce stress in individuals because of their patterns’ connections to nature. Fractal structures can even be seen in familiar real-life objects like trees or cauliflowers. Fractal geometry, with its ability to create complicated effects from simple formulas, provides a way to connect mathematics with visual results that are “spontaneously attractive, and often breathtakingly beautiful". The act of creating fractals can spark curiosity, enabling participants to generate vastly different results …

A Technical And Statistical Analysis Of Unleaded Aviation Fuel (Ul94) Adoption In A High- Volume Collegiate Aviation Environment, Nicholas D. Wilson, Ryan Guthridge, Brandon Wild, Jeremy Roesler, Daniel Kasowski, Nick Geinert, Aaron Terbest, Aaron Fettig, Robert Kraus

Journal of Aviation Technology and Engineering

The University of North Dakota (UND) adopted unleaded aviation fuel (UL94) for approximately a four-month period in the summer and early fall of 2023. The UL94 fuel was used in all reciprocating engine fleets based at the university’s primary training airport, Grand Forks International Airport in North Dakota. During the operational implementation of UL94, the UND flew 46,600 flight hours, consuming 386,778 gallons of fuel across all fleets powered by Lycoming engines. After approximately two months of using UL94, operational reports and maintenance inspections began to indicate potential for exhaust valve seat recession (EVSR), although early indications were limited in …

Contributing Factors To Low Airspeed On Climb-Out As A Precursor To Loss Of Control In Flight, Owen D. Poborsky

Journal of Aviation Technology and Engineering

The nature of aviation is not without inherent risk. Conducting training flight operations increases these inherent risks. Flight data monitoring and voluntary safety action programs seek to reduce risk, as seen in their success at commercial airlines. These successes are slowly permeating into general aviation through programs such as the National General Aviation Flight Information Database (NGAFID). The NGAFID is a program funded by the Federal Aviation Administration that allows general aviation operators to have the ability to collect and share de-identified flight data on an aggregate level to identify trends and increase safety margins during flight operations. This study …