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Conv4rec: A 1‑By‑1 Convolutional Autoencoder For User Profiling Through Joint Analysis Of Implicit And Explicit Feedbacks, Antoine Ledent, Petr Kasalický, Rodrigo Alves, Hady Wirawan Lauw Sep 2025

Conv4rec: A 1‑By‑1 Convolutional Autoencoder For User Profiling Through Joint Analysis Of Implicit And Explicit Feedbacks, Antoine Ledent, Petr Kasalický, Rodrigo Alves, Hady Wirawan Lauw

Research Collection School Of Computing and Information Systems

We introduce a new convolutional autoencoder architecture for user modeling and recommendation tasks with several improvements over the state of the art. First, our model has the flexibility to learn a set of associations and combinations between different interaction types in a way that carries over to each user and item. Second, our model is able to learn jointly from both the explicit ratings and the implicit information in the sampling pattern (which we refer to as ”implicit feedback”). It can also make separate predictions for the probability of consuming content and the likelihood of granting it a high rating …


Finding Safety Violations Of Ai-Enabled Control Systems Through The Lens Of Synthesized Proxy Programs, Jieke Shi, Zhou Yang, Junda He, Bowen Xu, Dongsun Kim, Donggyun Han, David Lo Sep 2025

Finding Safety Violations Of Ai-Enabled Control Systems Through The Lens Of Synthesized Proxy Programs, Jieke Shi, Zhou Yang, Junda He, Bowen Xu, Dongsun Kim, Donggyun Han, David Lo

Research Collection School Of Computing and Information Systems

Given the increasing adoption of modern AI-enabled control systems, ensuring their safety and reliability has become a critical task in software testing. One prevalent approach to testing control systems is falsification, which aims to find an input signal that causes the control system to violate a formal safety specification using optimization algorithms. However, applying falsification to AI-enabled control systems poses two significant challenges: (1) it requires the system to execute numerous candidate test inputs, which can be time-consuming, particularly for systems with AI models that have many parameters, and (2) multiple safety requirements are typically defined as a conjunctive specification, …


Robface: A Test Suite For Efficient Robustness Evaluation Of Face Recognition Systems, Ruihan Zhang, Jun Sun Sep 2025

Robface: A Test Suite For Efficient Robustness Evaluation Of Face Recognition Systems, Ruihan Zhang, Jun Sun

Research Collection School Of Computing and Information Systems

Face recognition is a widely used authentication technology in practice, where robustness is required. It is thus essential to have an efficient and easy-to-use method for evaluating the robustness of (possibly third-party) trained face recognition systems. Existing approaches to evaluating the robustness of face recognition systems are either based on empirical evaluation (e.g., measuring attacking success rate using state-of-the-art attacking methods) or formal analysis (e.g., measuring the Lipschitz constant). While the former demands significant user efforts and expertise, the latter is extremely time-consuming. In pursuit of a comprehensive, efficient, easy-to-use, and scalable estimation of the robustness of face recognition systems, …


Weight Gain Among Tuberculosis Patients And Its Association With Socio-Demographic Profile And Disease-Related Characteristics In Urban And Rural Areas Of Mysuru., Sana Khader M, Smitha Malenahalli Chandrashekarappa, Anchu R Nath, Arun Gopi Sep 2025

Weight Gain Among Tuberculosis Patients And Its Association With Socio-Demographic Profile And Disease-Related Characteristics In Urban And Rural Areas Of Mysuru., Sana Khader M, Smitha Malenahalli Chandrashekarappa, Anchu R Nath, Arun Gopi

Digital Journal of Clinical Medicine

Background: Tuberculosis remains a major public health burden in India, accounting for 25% of the global tuberculosis cases. Weight gain during tuberculosis treatment is a key recovery indicator influenced by sociodemographic and clinical factors. Addressing these challenges is crucial for achieving India’s Tuberculosis elimination goal by 2025.

Objectives: To assess weight gain across different phases of anti tubercular therapy among tuberculosis patients in urban and rural Mysuru, and to determine its association with sociodemographic and disease-related characteristics.

Methodology: A retrospective cross-sectional study was done using secondary data of tuberculosis patients who attended primary health care centers in …


Personalised Learning In Medical Education – A Futuristic Model For Individual Learning Styles, Sujatha Mahadevarao Premnath, Ashwin Chand Ravichandran, Sivaa Rajendran Sep 2025

Personalised Learning In Medical Education – A Futuristic Model For Individual Learning Styles, Sujatha Mahadevarao Premnath, Ashwin Chand Ravichandran, Sivaa Rajendran

Digital Journal of Clinical Medicine

Medical education is transitioning from the traditional teacher-centred to a student-centred model, and an approach that caters to the diverse needs of the learner is necessary to meet these needs. Personalised learning is one such strategy that offers learning content based on individual profiles, learning styles, pace, and competency gaps. Here, the individual student receives content based on their preference, where the content can be created by educators leveraging technology, an adaptive learning platform, and artificial intelligence. It provides an inclusive and efficient learning platform that helps in creating more efficient medical graduates. This article explores the concept of personalized …


What Are The Limits To Smart Innovation? The Digital Underground Initiative And New Frontiers Of “Smartness” In Singapore, Prerona Das, Orlando Woods, Lily Kong Sep 2025

What Are The Limits To Smart Innovation? The Digital Underground Initiative And New Frontiers Of “Smartness” In Singapore, Prerona Das, Orlando Woods, Lily Kong

Research Collection College of Integrative Studies

This paper argues that the emergence of new frontiers of smart transformation, such as underground spaces, can pose significant challenges to the implementation of “smart” technological solutions. Exploring the case of Singapore’s Digital Underground initiative, we show that elements such as material complexity, co-ordination between stakeholders, and the availability of appropriate regulatory and administrative frameworks can problematize the implementation of subterranean smart initiatives. By considering multistake-holder perspectives on these “more-than-technological” factors, this paper offers lessons for urban planners, policymakers, and developers in cities around the world that are keen to leverage technology to unlock the potential of underground space.


Don't Miss The Tmc Library Webinar Series, Sandra Y. Desjardins, Jenny Stockton Sep 2025

Don't Miss The Tmc Library Webinar Series, Sandra Y. Desjardins, Jenny Stockton

TMC Library Newsletter (2015-)

Whether you're a student, a physician, or a faculty member, every great research project starts with a clear plan. This session will walk you through the essential steps of turning a research idea into a structured plan using the PICO framework. We'll cover how to develop focused research questions and discuss the value of using established protocols to ensure your work is sound and reproducible.

Come learn the foundational skills needed for successful research in a welcoming and practical "Lunch & Learn" environment


Houston’S Changing Skyline: Herman Hospital 1947-1976, Kelsey Koym Sep 2025

Houston’S Changing Skyline: Herman Hospital 1947-1976, Kelsey Koym

TMC Library Newsletter (2015-)

Hermann Hospital, as it was originally known, has been a cornerstone of Houston’s medical community for more than a century. Over the years, the institution experienced major expansions, several name changes, and even a few scandals, all while shaping the growth of the Texas Medical Center. The photographs featured in this exhibit, taken between 1947 and 1976, highlight both the hospital’s transformation and the evolving Houston skyline. They also capture milestones such as the launch of Life Flight, which forever changed emergency medical care.


Publishing Support At The Tmc Library, Chad Metz Sep 2025

Publishing Support At The Tmc Library, Chad Metz

TMC Library Newsletter (2015-)

Explore our newly updated Publishing Support LibGuide, designed to help you navigate the world of scholarly publishing. Learn about open access and “read and publish” agreements, and find out what publishing resources are available through the TMC Library.


The Imperial Gaze: Affective Governance, Hybrid Cartography, And China’S U-Shaped Line, William A. Callahan Sep 2025

The Imperial Gaze: Affective Governance, Hybrid Cartography, And China’S U-Shaped Line, William A. Callahan

Research Collection School of Social Sciences

This article develops ‘the imperial gaze’ concept to explore how maps not only represent the world, but also do things in geopolitics, even provoking mass demonstrations. It examines China’s early-modern and contemporary maps to highlight how they create an imperial gaze that guides Chinese understandings of world order. If your cartographic ‘view of the world’ produces your ideological ‘worldview’, then it is important to see how China’s early-modern maps inform the PRC’s twenty-first-century claims in the South China Sea. The article argues that Chinese cartography does things in geopolitics by mobilising the affective governance of an assemblage of hybrid combinations …


Prevalence Of Depression, Anxiety, Burden, Burnout, And Stress In Informal Caregivers: An Umbrella Review Of Meta-Analyses, Xun Ci Soh, Andree Hartanto, Naoki Ling, Mayr Reyes, Lester Sim, Nadyanna M. Majeed Sep 2025

Prevalence Of Depression, Anxiety, Burden, Burnout, And Stress In Informal Caregivers: An Umbrella Review Of Meta-Analyses, Xun Ci Soh, Andree Hartanto, Naoki Ling, Mayr Reyes, Lester Sim, Nadyanna M. Majeed

Research Collection School of Social Sciences

Informal caregiving is a physically and emotionally taxing role that has a profound impact on caregivers’ emotional and mental well-being. Previous research has examined the mental health of caregivers and found elevated levels of depression, anxiety, burden, burnout, or stress. However, the global rates of the five mental health factors and/or outcomes (i.e., depression, anxiety, burden, burnout, and stress) among caregivers remain largely unclear. Therefore, this umbrella review examines the prevalence of these factors and/or outcomes, including various subgroup factors, such as gender, medical and/or psychological condition of the care recipient, region, and assessment tools. A systematic search was conducted …


The Moderating Role Of Trait Online Disinhibition In Exacerbating The Online Victim-Bully Cycle, Sandeeshwara K Tennakoon Appuhamillage Kasturiratna, Andree Hartanto Sep 2025

The Moderating Role Of Trait Online Disinhibition In Exacerbating The Online Victim-Bully Cycle, Sandeeshwara K Tennakoon Appuhamillage Kasturiratna, Andree Hartanto

Research Collection School of Social Sciences

The growth of the internet and social media as a communication platform has increased the incidence of cyberbullying victimisation. While there has been increasing research interest on the antecedents of cyberbullying perpetration, little is known on why some individuals who themself experience cyber victimisation are more likely to become cyberbullying perpetrators. Considering the large number of individuals who experience cyberbullying victimisation in the current, highly digitalised world, this trend of victims turning into bullies poses a worrisome possibility and deserves research attention. One promising individual difference that could potentially moderate the relationship between cyberbullying victimisation can lead to cyberbullying perpetration …


Merit Transference And The Paradox Of Merit Inflation, Matthew Hammerton Sep 2025

Merit Transference And The Paradox Of Merit Inflation, Matthew Hammerton

Research Collection School of Social Sciences

Many religious traditions and ethical systems hold that individuals accrue merit through their good intentions, acts, and character, and demerit through their bad intentions, acts, and character. This merit and demerit, accumulated by individuals throughout their lives, gives each person a kind of ethical “score” that can determine what they deserve, and influence whether good or bad things happen to them (e.g., divine punishments and rewards, a favourable or unfavourable rebirth, etc.). In some traditions (most notably Buddhism, but also to a limited extent in Hinduism, Islam, and Christianity), “merit transference” is a feature of these merit-based ethical systems. This …


The Decline And Transformation Of Smallholders In Chinese Agriculture: National Trends, Qian Forrest Zhang, Meiling Wu Sep 2025

The Decline And Transformation Of Smallholders In Chinese Agriculture: National Trends, Qian Forrest Zhang, Meiling Wu

Research Collection School of Social Sciences

Using data from official statistical sources and a nationally representative survey, we find that since 2001, China’s agricultural labor force has declined by over 50 percent—a loss of over 200 million smallholders, probably the largest in human history. This trend is the most pronounced in livestock sectors: from 2012 to 2021, 62.5 million smallholder units have disappeared. The 150 million remaining smallholders are mostly commodity producers, participating widely in commodity relations to access agrochemicals, machinery, rental land, and wage labor to produce for markets. The ageing smallholder population also face challenges in intergenerational reproduction, which will accelerate its decline.


Supporting Satisfaction, Satisfying Support: Bidirectional Associations Of Social Support And Life Satisfaction, Jonathan Louis Jie Sheng Chia, Andree Hartanto, William Tov Sep 2025

Supporting Satisfaction, Satisfying Support: Bidirectional Associations Of Social Support And Life Satisfaction, Jonathan Louis Jie Sheng Chia, Andree Hartanto, William Tov

Research Collection School of Social Sciences

Existing literature has explored the impact of social support (SS) on life satisfaction (LS). However, the reciprocal relationship—that is, the influence of LS on SS—remains understudied, despite extant theoretical support. In addressing this gap, the present study employed bivariate latent growth modeling to examine bidirectional associations between SS and LS trajectories among 8,449 middle-aged and older adults in Singapore, over seven waves spanning almost 6 years. Results provided evidence supporting the notion of bidirectional associations. Specifically, baseline SS positively predicted subsequent changes in LS, and baseline LS positively predicted subsequent changes in SS. Findings underscore the potential for interventions and …


Accordance And Conflict Between Religious And Scientific Precautions Against Covid-19 In 27 Societies, T. Samore, D.M.T. Fessler, A.M. Sparks, C. Holbrook, L. Aarøe, C.G. Baeza, M.T. Barbato, P. Barclay, R. Berniūnas, J. Contreras-Garduño, B. Costa-Neves, M.P. Grazioso, P. Elmas, P. Fedor, Li, Norman P., R. Fernández-Morales, L. Garcia-Marques, P. Giraldo-Perez, P. Gul, F. Habacht Sep 2025

Accordance And Conflict Between Religious And Scientific Precautions Against Covid-19 In 27 Societies, T. Samore, D.M.T. Fessler, A.M. Sparks, C. Holbrook, L. Aarøe, C.G. Baeza, M.T. Barbato, P. Barclay, R. Berniūnas, J. Contreras-Garduño, B. Costa-Neves, M.P. Grazioso, P. Elmas, P. Fedor, Li, Norman P., R. Fernández-Morales, L. Garcia-Marques, P. Giraldo-Perez, P. Gul, F. Habacht

Research Collection School of Social Sciences

Meaning-making systems underlie perceptions of the efficacy of threat-mitigating behaviors. Religion and science both offer threat mitigation, yet these meaning-making systems are often considered incompatible. Do such epistemological conflicts swamp the desire to employ diverse precautions against threats? Or do individuals—particularly individuals who are highly reactive to threats—hedge their bets by using multiple threat-mitigating practices despite their potential epistemological incompatibility? Complicating this question, perceptions of conflict between religion and science likely vary across cultures; likewise, pragmatic features of precautions prescribed by some religions make them incompatible with some scientifically-based precautions. The COVID-19 pandemic elicited diverse precautions thus providing an opportunity …


A Multifaceted Nudge-Based Intervention To Reduce Smartphone Use: Findings From A Randomized Cross-Over Trial, K. T. A. Sandeeshwara Kasturiratna, Yi Jing Chua, Andree Hartanto Sep 2025

A Multifaceted Nudge-Based Intervention To Reduce Smartphone Use: Findings From A Randomized Cross-Over Trial, K. T. A. Sandeeshwara Kasturiratna, Yi Jing Chua, Andree Hartanto

Research Collection School of Social Sciences

The widespread use of smartphones has raised concerns about problematic usage behaviors, including excessive screentime and frequent phone checking, which can disrupt daily functioning. This study aimed to evaluate the effectiveness of a multifaceted nudge-based intervention in reducing smartphone use through subtle changes to smartphone settings. The intervention incorporated adjustments such as disabling face/touch ID, setting longer passwords, switching to grayscale mode, and removing social media apps from the home screen. A randomized within-subject cross-over trial with counterbalancing was conducted over a two-week period using a daily diary approach paired with objective smartphone usage data to track the impact of …


Reimagining Academic Assessment In The Age Of Ai, Matthew Hammerton Sep 2025

Reimagining Academic Assessment In The Age Of Ai, Matthew Hammerton

Research Collection School of Social Sciences

In ‘Reimagining Academic Assessment in the Age of AI’, Matthew Hammerton examines the challenges and opportunities posed by generative AI for higher education assessment. He critiques common responses like banning AI, reverting to in-class exams, or abandoning essays altogether, arguing that they fail to preserve the deeper pedagogical goals of higher order, independent thinking. Instead, Hammerton proposes a guiding principle of intellectual responsibility: students should be accountable for explaining and defending each major choice in their work—regardless of whether they use AI tools. To operationalise this, he advocates for reintegrating oral examinations (‘vivas’) alongside written essays. In this model, students …


Noncontact Diffuse Optical Imaging Of Blood Flow And Oxygenation Distributions In Reconstructive Rat Skin Flaps, Samaneh Rabienia Haratbar, Fatemeh Hamedi, Mehrana Mohtasebi, Faraneh Fathi, Faezeh Akbari, Dara Singh, L. I.U. Xuhui, Li Chen, Lesley Wong, Lei Chen, Guoqiang Yu Sep 2025

Noncontact Diffuse Optical Imaging Of Blood Flow And Oxygenation Distributions In Reconstructive Rat Skin Flaps, Samaneh Rabienia Haratbar, Fatemeh Hamedi, Mehrana Mohtasebi, Faraneh Fathi, Faezeh Akbari, Dara Singh, L. I.U. Xuhui, Li Chen, Lesley Wong, Lei Chen, Guoqiang Yu

Surgery Faculty Publications

Perioperative identification of ischemic-hypoxic tissue is essential for reducing the risk of mastectomy skin flap necrosis (MSFN), a major complication following mastectomy. Implant-based breast reconstruction is jeopardized in the presence of MSFN. However, existing technologies are limited by depth insensitivity, dye-related risks, the need for contact sensors, and an inability to simultaneously assess both blood flow and oxygenation. A multi-wavelength speckle contrast diffuse correlation tomography (MW-scDCT) system was developed for noncontact, dye-free, and depth-sensitive imaging of tissue hemodynamics in a rat model incorporating four distinct flap scenarios: sham (SH), implant (IM), half necrosis (HN), and full necrosis (FN), representing varying …


Microwave Ablation For Hepatocellular Carcinoma In Cirrhotic Patients With Diuretic-Resistant Ascites, Sawyer Blair, Jack Newcomer, Driss Raissi Sep 2025

Microwave Ablation For Hepatocellular Carcinoma In Cirrhotic Patients With Diuretic-Resistant Ascites, Sawyer Blair, Jack Newcomer, Driss Raissi

Surgery Faculty Publications

Objectives: The purpose of this study was to evaluate the feasibility, safety, and efficacy of computed tomography (CT)-guided percutaneous microwave ablation (MWA) of liver hepatocellular carcinoma (HCC) lesions in patients with pre-existing diuretic-resistant ascites. There is logical hesitation among clinicians to pursue MWA in these decompensated patients for fear of worsening an already bleak prognosis, but there is limited evidence to justify this behavior. Material and Methods: A retrospective review of HCC treated with percutaneous MWA at a single center was performed. 18 patients who underwent CT-guided MWA with pre-existing diuretic-resistant ascites were identified. A control group of 29 patients …


Brigham-Kanner Property Rights Journal, Volume 14, William & Mary Law School Sep 2025

Brigham-Kanner Property Rights Journal, Volume 14, William & Mary Law School

Brigham-Kanner Property Rights Journal

Gideon Kanner Remembrance

September 12-13, 2024

Restructuring Property: A Tribute to Lee Fennell

Background Principles, General Law, & Constitutional Property

Roundtable: Unfinished Business & Emerging Issues

Property Rights and Housing In Crisis

Government Trespass: The Fourth Amendment "Open Fields" Doctrine Turns 100


Genome-Wide Association Study Provides Novel Insight Into The Genetic Architecture Of Severe Obesity, Mohanraj Krishnan, Mohammad Yaser Anwar, Anne E Justice, Geetha Chittoor, Hung-Hsin Chen, Rashedeh Roshani, Alyssa Scartozzi, Rachel R Dickerson, Roelof A J Smit, Michael H Preuss, Nathalie Chami, Benjamin S Hadad, Esteban J Parra, Miguel Cruz, Qin Hui, Peter W F Wilson, Yan V Sun, Xiaoyu Zhang, Gregorio V Linchangco, Sharon L R Kardia, Jessica D Faul, David R Weir, Lawrence F Bielak, Heather M Highland, Kristin L Young, Baiyu Qi, Yujie Wang, Myriam Fornage, Christopher Haiman, Iona Cheng, Ulrike Peters, Charles Kooperberg, Steven Buyske, Joseph B Mccormick, Susan P Fisher-Hoch, Frida Lona-Durazo, Jesus Peralta, Jamie Gomez-Zamudio, Stephen S Rich, Kendra R Ferrier, Ethan M Lange, Christopher R Gignoux, Eimear E Kenny, Genevieve L Wojcik, Kelly Cho, Michael J Gaziano, Luc Djousse, Shuwei Liu, Dhananjay Vaidya, Renée De Mutsert, Navya S Josyula, Christopher R Bauer, Wei Zhao, Ryan W Walker, Jennifer A Smith, Leslie A Lange, Mariah C Meyer, Ching-Ti Liu, Lisa R Yanek, Miryoung Lee, Laura M Raffield, Ruth J F Loos, Penny Gordon-Larsen, Jennifer E Below, Kari E North, Mariaelisa Graff Sep 2025

Genome-Wide Association Study Provides Novel Insight Into The Genetic Architecture Of Severe Obesity, Mohanraj Krishnan, Mohammad Yaser Anwar, Anne E Justice, Geetha Chittoor, Hung-Hsin Chen, Rashedeh Roshani, Alyssa Scartozzi, Rachel R Dickerson, Roelof A J Smit, Michael H Preuss, Nathalie Chami, Benjamin S Hadad, Esteban J Parra, Miguel Cruz, Qin Hui, Peter W F Wilson, Yan V Sun, Xiaoyu Zhang, Gregorio V Linchangco, Sharon L R Kardia, Jessica D Faul, David R Weir, Lawrence F Bielak, Heather M Highland, Kristin L Young, Baiyu Qi, Yujie Wang, Myriam Fornage, Christopher Haiman, Iona Cheng, Ulrike Peters, Charles Kooperberg, Steven Buyske, Joseph B Mccormick, Susan P Fisher-Hoch, Frida Lona-Durazo, Jesus Peralta, Jamie Gomez-Zamudio, Stephen S Rich, Kendra R Ferrier, Ethan M Lange, Christopher R Gignoux, Eimear E Kenny, Genevieve L Wojcik, Kelly Cho, Michael J Gaziano, Luc Djousse, Shuwei Liu, Dhananjay Vaidya, Renée De Mutsert, Navya S Josyula, Christopher R Bauer, Wei Zhao, Ryan W Walker, Jennifer A Smith, Leslie A Lange, Mariah C Meyer, Ching-Ti Liu, Lisa R Yanek, Miryoung Lee, Laura M Raffield, Ruth J F Loos, Penny Gordon-Larsen, Jennifer E Below, Kari E North, Mariaelisa Graff

The Brown Foundation: Institute of Molecular Medicine

Severe obesity (SevO) is a primary driver of cardiovascular diseases (CVD), cardiometabolic diseases (CMD) and several cancers, with a disproportionate impact on marginalized populations. SevO is an understudied global health disease, limiting knowledge about its mechanisms and impacts. In genome-wide association study (GWAS) meta-analyses of the tail end of the BMI distribution (≥95th percentile BMI) and two SevO phenotypes [Obesity Class III BMI ≥ 40 kg/m2 and Obesity Class IV BMI ≥ 50 kg/m2] in 159,359 individuals across eleven ancestrally diverse population-based studies followed by replication in 480,897 individuals across six ancestrally diverse studies, we identified and replicated three novel …


Utilization Of Outpatient Mental Health Services During And 2 Years After The Covid-19 Pandemic, Michelle A Hayek, Hye-Chung Kum, Sulki Park, Robert Ohsfeldt, Mark A Lawley, Michelle J Bovin Sep 2025

Utilization Of Outpatient Mental Health Services During And 2 Years After The Covid-19 Pandemic, Michelle A Hayek, Hye-Chung Kum, Sulki Park, Robert Ohsfeldt, Mark A Lawley, Michelle J Bovin

The Brown Foundation: Institute of Molecular Medicine

Objective: Analyze the impact of COVID-19 on outpatient mental health (OP-MH) utilization patterns, particularly telehealth, across eight different MH conditions with a 2-year follow-up.

Methods: This population-based cohort study uses a 5% random sample of Medicare beneficiaries aged ≥18 and newly diagnosed with one of the eight MH disorders: psychotic, depressive, bipolar, anxiety, trauma-related, substance-use, other MH disorders, and two or more MH disorders. Monthly OP-MH utilization patterns were compared among patients in 2020-2021 newly diagnosed in 2019 to comparable prepandemic cohorts newly diagnosed in 2017. Multiple logistic regression models were conducted to examine differences in telehealth utilization across MH …


Patients´ Characteristics And Six-Month Outcomes Of Patients With Atrial Fibrillation In Kenya: A Retrospective Observational Cohort Study From The National Cardiovascular Registry, Salim Abdallah, Jasmit Shah, Anders Barasa, Felix Barasa, Benard Gitura, Mzee Ngunga Sep 2025

Patients´ Characteristics And Six-Month Outcomes Of Patients With Atrial Fibrillation In Kenya: A Retrospective Observational Cohort Study From The National Cardiovascular Registry, Salim Abdallah, Jasmit Shah, Anders Barasa, Felix Barasa, Benard Gitura, Mzee Ngunga

Internal Medicine, East Africa

Introduction: atrial fibrillation is increasingly diagnosed in Kenya due to the persistence of rheumatic heart disease and the rising burden of cardiovascular risk factors. We aim to describe the baseline, clinical, treatment characteristics, and six-month outcomes of patients diagnosed with atrial fibrillation in Kenya.

Methods: a retrospective observational cohort study design was employed. Data were obtained from three Kenyan referral hospitals, including public and private institutions. Baseline and six-month data were collected. Depending on the type of variable, data were summarized descriptively.

Results: two hundred forty participants were enrolled, with a median age of 59.0 (IQR: 42.0-75.8). …


Left Bundle Area Pacing Outcomes Among Patients With Very Wide Qrs – Insights From An African Registry, Willy Mucyo, Mzee Ngunga, Miriam Msunza, Jeilan Mohamed, Marcus Ngantcha, Brian Vezi Sep 2025

Left Bundle Area Pacing Outcomes Among Patients With Very Wide Qrs – Insights From An African Registry, Willy Mucyo, Mzee Ngunga, Miriam Msunza, Jeilan Mohamed, Marcus Ngantcha, Brian Vezi

Internal Medicine, East Africa

Background: Left Bundle Area Pacing (LBAP) is a promising alternative to conventional cardiac resynchronization therapy. There is a high prevalence of dilated cardiomyopathy in Africa, which is often associated with very wide QRS. However, data on LBAP outcomes in Africa are limited. Objective To evaluate the procedural and clinical outcomes of LBAP among African patients with very wide QRS durations.

Methods: The Multicenter African Cardiac Outcomes in Pacing (MACOP) registry enrolled 311 patients in Kenya and South Africa who underwent LBAP between 2021 and 2024. We evaluated procedural and clinical outcomes. Patients were stratified by baseline QRSd (normal …


2025 September, Morehead State University. Office Of Communications & Marketing. Sep 2025

2025 September, Morehead State University. Office Of Communications & Marketing.

Morehead State Press Release Archive, 1961 to the Present

Press releases for September of 2025.


On The Chlorobenzene-Ammonia Cluster Reaction: Entrance Channel Dynamics, 2cr2pi Spectroscopy, And Ion Imaging Of The Reaction Dynamics, Ronald Mutete, Damian Kokkin, Natan Fessahaye, Thomas R. Howell, Richard A. Loomis, Scott A. Reid Sep 2025

On The Chlorobenzene-Ammonia Cluster Reaction: Entrance Channel Dynamics, 2cr2pi Spectroscopy, And Ion Imaging Of The Reaction Dynamics, Ronald Mutete, Damian Kokkin, Natan Fessahaye, Thomas R. Howell, Richard A. Loomis, Scott A. Reid

Chemistry Faculty Research and Publications

Prior studies of halobenzene–ammonia complexes have shown that the nature of the cationic intermediate (i.e., Wheland-type vs ion-radical) may play a key role in determining the reaction products. To probe this link, we report here the reaction dynamics of the chlorobenzene-ammonia 1:1 complex (PhCl···NH3) using product ion imaging following two-color resonant two-photon ionization. A threshold value of 8.863 ± 0.008 eV was determined for the appearance of protonated aniline, which accompanies Cl atom loss and is the dominant product channel at energies near threshold. Scanning down to energies close to threshold, we find no evidence for a roaming …


Deepmvp: Deep Learning Models Trained On High-Quality Data Accurately Predict Ptm Sites And Variant-Induced Alterations, Bo Wen, Chenwei Wang, Kai Li, Ping Han, Matthew V Holt, Sara R Savage, Jonathan T Lei, Yongchao Dou, Zhiao Shi, Yi Li, Bing Zhang Sep 2025

Deepmvp: Deep Learning Models Trained On High-Quality Data Accurately Predict Ptm Sites And Variant-Induced Alterations, Bo Wen, Chenwei Wang, Kai Li, Ping Han, Matthew V Holt, Sara R Savage, Jonathan T Lei, Yongchao Dou, Zhiao Shi, Yi Li, Bing Zhang

Center on Aging Staff Publications

Post-translational modifications (PTMs) are critical regulators of protein function, and their disruption is a key mechanism by which missense variants contribute to disease. Accurate PTM site prediction using deep learning can help identify PTM-altering variants, but progress has been limited by the lack of large, high-quality training datasets. Here, we introduce PTMAtlas, a curated compendium of 397,524 PTM sites generated through systematic reprocessing of 241 public mass-spectrometry datasets, and DeepMVP, a deep learning framework trained on PTMAtlas to predict PTM sites for phosphorylation, acetylation, methylation, sumoylation, ubiquitination and N-glycosylation. DeepMVP substantially outperforms existing tools across all six PTM types. Its …


Improvement Of The Face Recognition Systems Security Against Morph Attacks Using The Developed Siamese Neural Network, Sura Abed Sarab Hussien, Thair Abed Sarab Hussien, Nada Hussein M. Ali Sep 2025

Improvement Of The Face Recognition Systems Security Against Morph Attacks Using The Developed Siamese Neural Network, Sura Abed Sarab Hussien, Thair Abed Sarab Hussien, Nada Hussein M. Ali

Mesopotamian Journal of CyberSecurity

Face Recognition Systems (FRS) are increasingly targeted by morphing attacks, where facial features of multiple individuals are blended into a synthetic image to deceive biometric verification. This paper proposes an enhanced Siamese Neural Network (SNN)-based system for robust morph detection. The methodology involves four stages. First, a dataset of real and morphed images is generated using StyleGAN, producing high-quality facial images. Second, facial regions are extracted using Faster Region-based Convolutional Neural Networks (R-CNN) to isolate relevant features and eliminate background noise. Third, a Local Binary Pattern-Convolutional Neural Network (LBP-CNN) is used to build a baseline FRS and assess its susceptibility …


Preoperative Focused Echocardiography On Patients With Fractured Neck Of Femur. Echonof-Iii Trial: Study Protocol For A Multicenter Randomized Controlled Trial, Ximena Cid-Serra, Alistair Royse, Andrea Bowyer, David Canty, Daniel Sessler, Sandy Clarke-Errey, Andre Denault, Dina Logiudice, Guy Ludbrook, D-Yin Lin, Yang Yang, Kavi Haji, Lisa Zucherrelli, Andrew J Palmer, Benjamin Piper, Thar Nyan Lwin, Stefan Dieleman, David Eccleston, Alwin Chuan, Richard Cooper, Gregory Henderson, Colin Royse Sep 2025

Preoperative Focused Echocardiography On Patients With Fractured Neck Of Femur. Echonof-Iii Trial: Study Protocol For A Multicenter Randomized Controlled Trial, Ximena Cid-Serra, Alistair Royse, Andrea Bowyer, David Canty, Daniel Sessler, Sandy Clarke-Errey, Andre Denault, Dina Logiudice, Guy Ludbrook, D-Yin Lin, Yang Yang, Kavi Haji, Lisa Zucherrelli, Andrew J Palmer, Benjamin Piper, Thar Nyan Lwin, Stefan Dieleman, David Eccleston, Alwin Chuan, Richard Cooper, Gregory Henderson, Colin Royse

Faculty, Staff and Student Publications

Background: Hip fractures are common in older people and are associated with high perioperative mortality. Prompt surgical intervention within the first 48 h of fraction reduces complications; however, surgical urgency often precludes a comprehensive preoperative cardiac evaluation. Preliminary data suggests that performing a focused cardiac ultrasound (FCU) before surgery may reduce postoperative complications. We therefore propose to test the primary hypothesis that FCU reduces a 30-day composite of mortality and serious complications.

Methods: We plan a definitive multicenter pragmatic randomized trial that will enroll 2000 adults with hip fractures. Participants will be randomized before surgery to either receive FCU as …