Digital Commons Network^™

Oligomerisation Of Ku From Mycobacterium Tuberculosis Promotes Dna Synapsis, Sayma Zahid, Ankita Chadda, Eric Galburt, Et Al.

2020-Current year OA Pubs

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is estimated to infect nearly one-quarter of the global population. A key factor in its resilience and persistence is its robust DNA repair capacity. Non-homologous end joining (NHEJ) is the primary pathway for repairing DNA double-strand breaks (DSBs) in many organisms, including Mtb, where it is mediated by the Ku protein and the multifunctional LigD enzyme. In this study, we demonstrate that Ku is essential for mycobacterial survival under DNA-damaging conditions. Using cryogenic electron microscopy (cryo-EM), we solved high-resolution structures of both the apo and DNA-bound forms of the Ku-Mtb homodimer. …

Transcription-Replication Collisions Trigger High-Fidelity Replication Reset, Katelin M Hagstrom, Alice X Wen, Jennifer A Halliday, Susan M Rosenberg, Christophe Herman

Faculty, Staff and Students Publications

Double-stranded DNA ends arise from external agents or cellular processes like transcription-replication collisions (TRCs), threatening genome stability. Here, we performed genomic CRISPRi screens to uncover DNA end formation factors in Escherichia coli. We discovered that translation-transcription decoupling causes DNA end formation through a TRC-dependent pathway, which is lethal when DNA end processing by RecBCD is disrupted, but not when recombination is disrupted. We find that TRCs cause replisome stalling followed by "rear-ending" from trailing replisomes which generates free DNA ends, rather than strand breaks. Surprisingly, these DNA ends are resolved through a process we call "replication reset", where the stalled …

Multimodal Cardiac Imaging Of Immune-Mediated Complications Post Heart Transplantation: A Contemporary Review, James C Wilkinson, Marvin W Kronenberg, Chloe Carr, Malek Nayfeh, Tania Ruiz, Luke L Laws, Melissa Lou Silva, John A Wells, Leandro Slipczuk, Emily T Lippincott, John J Carr, Kaushik Amancherla, Cameron Henry, David Parra, Kelly Schlendorf, Quinn S Wells, Sean G Hughes, Jonathan Soslow

Faculty, Staff and Students Publications

Heart transplantation significantly enhances survival and quality of life for patients with end-stage heart failure. Despite advances in surgical and postoperative care, immune-mediated complications, acute graft rejection and cardiac allograft vasculopathy (CAV), remain major barriers to long-term success. Acute rejection predominantly affects early posttransplant survival, whereas CAV becomes a leading cause of mortality in later years. The gold standards for diagnosis, endomyocardial biopsy for rejection and coronary angiography for CAV, are invasive and imperfect. Noninvasive multimodality imaging is increasingly used to complement or, in selected scenarios, defer invasive testing. Echocardiography with strain detects early myocardial dysfunction when ejection fraction is …

Maternal Obesogenic Diet Exposure Regulates The Offspring Gut Liver Axis And Fibroinflammatory Liver Disease, Naresh Naik Ramavath, Oğuz Özler, Holly Hinrichs, Francisco R Victorino, Vung Lian, Monica Young, Tarin M Bigley, Michael D Thompson

2020-Current year OA Pubs

Maternal obesogenic diet exposure (MODE) promotes fibroinflammatory liver disease in offspring via vertical transfer of an altered microbiome. The mechanism for how an altered offspring microbiome increases susceptibility to liver disease is not clear. A critical early life event termed the 'weaning reaction' is dependent on the early microbiome and when altered, results in worse pathologic inflammation. MODE attenuates the weaning reaction promoting worse liver disease in mice in an early microbiome-dependent manner. Using our MODE model and cross-fostering approaches we assessed the effect of MODE on neonatal gut-liver axis development. MODE shifts the bile acid (BA) profile, expression of …

Implementation Outcomes From The Hypertension Treatment In Nigeria Program: Results From A Type 2 Hybrid Interrupted Time Series Trial, Jiancheng Ye, Erica L Jamro, Guhan Iyer, Mark D Huffman, Et Al.

2020-Current year OA Pubs

BACKGROUND: The Hypertension Treatment in Nigeria Program was implemented across 60 primary healthcare centers (PHCs) in Nigeria to improve hypertension treatment and control using the World Health Organization's HEARTS package. This study reports the program's implementation outcomes.

METHODS: The Hypertension Treatment in Nigeria Program used a type 2 hybrid interrupted time series design, and data were collected from January 2020 to December 2023. The RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework guided the evaluation, focusing on key metrics such as patients' and clinics' characteristics, prescription rate of fixed dose combination (FDC) drugs, medication availability, and retention.

RESULTS: Among 21,922 …

Strengthening Implementation Science Research To Improve Adolescent And Young Adult Hiv-Prevention And Care In Sub-Saharan Africa: Patc3h-In, Geri R Donenberg, Ucheoma Nwaozuru, Sylvia Adebajo, Joseph D Tucker, Juliet Iwelunmor, Lisa M Kuhns, Brenda Gati Mirembe, Lisa Hightow-Weidman, Brian Zanoni, Tapiwa A Tembo, Maria Felix Lupogo, Franklin Yates

2020-Current year OA Pubs

BACKGROUND: Despite significant progress in HIV prevention and treatment, uptake of evidence-based interventions among adolescents and young adults (AYA), particularly in low- and middle-income countries (LMICs), remains low. Implementation research can optimize strategies to enhance reach, uptake, and equitable access to these innovations. The Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource-Constrained Settings Implementation Science Network (PATC

METHODS: The PATC

RESULTS: The PATC

CONCLUSIONS: The PATC

CLINICAL TRIAL NUMBER: Not Applicable.

Successful Implementation Of Stroke Risk Screening For Sickle Cell Anemia In The Displace Study: Results Of A Cluster Randomized Trial, Alyssa M Schlenz, Monica L Hulbert, Et Al.

2020-Current year OA Pubs

BACKGROUND: Stroke risk screening using transcranial Doppler (TCD) is a critical evidence-based tool for children with sickle cell anemia (SCA) that has been poorly implemented in the United States. The Dissemination and Implementation of Stroke Prevention Looking at the Care Environment (DISPLACE) study was designed to improve rates of stroke risk screening for SCA using interventions informed by an extensive multi-level barriers and facilitators assessment. This report describes the final outcomes of a large, randomized implementation trial comparing two intervention arms: 1) an application designed to track TCD implementation, ProviderMinder™, versus 2) ProviderMinder™ plus a single coordinator intervention. All sites …

Lost In Translation: Is Data Protection Labour Law Protection?, Michele Molè

Comparative Labor Law & Policy Journal

This article critically examines how the European General Data Protection Regulation (GDPR) defines and applies the legal categories of “data subject” and “data controller” within employment relationships. Under the GDPR, employers who collect and process personal data are classified as data controllers, while employees are designated as data subjects. However, this article argues that such a “translation” of data protection categories, rights, and obligations into the regulation of workplace dynamics requires closer examination. The focus is on evaluating whether the GDPR’s rights and obligations for data subjects and data controllers accurately capture the agency and interests of employee and employer …

Comment - The Collective Aspect Of Job Seekers’ Data Rights, Katrina Ligett, Ayelet Gordon-Tapiero

Comparative Labor Law & Policy Journal

THE WORKPLACE is a complex and dynamic environment that mirrors societal relations and interactions. Given the inherent imbalance of power between employers and workers, as well as the lack of bargaining power of any individual worker, worker unions have emerged to provide workers with a collective voice and place them on more even footing with their employers, allowing them to achieve more than any single worker could on their own (Bok, 1971). Through the assertion of their members’ collective rights, worker unions have played a pivotal role in promoting rights such as fair wages, safe work conditions, health benefits, and …

High Prevalence And Atypical Genotype Distribution Of Oral Human Papillomavirus In An East African Hiv Cohort: A Cross-Sectional Study, Ian G. Munabi, Adriane Kamulegeya, Dunstan Kalanzi, David P. Kateete, Fred Collins Semitala, Catherine-Lutalo Mwesigwa, Samuel Kalungi, Jennifer E. Cameron, Kimon Divaris, William Buwembo

School of Medicine Faculty Publications

BACKGROUND: Globally, Human Papillomavirus type 16 (HPV-16) is the predominant genotype associated with oropharyngeal cancers. However, little is known about the prevalence and type distribution of Oral Human Papillomavirus (OHPV) in people living with HIV (PLWHIV) in the East African region. The objective of this study was to document the prevalence and circulating genotypes of OHPV infection in a large cohort of PLWHIV attending an urban HIV clinic in Eastern Africa METHODS: This was a cross-sectional study among 1,715 participants of the Makerere University Joint AIDS Program clinic, located in Kampala, Uganda, in East Africa. A salivary sample was collected …

Clark Cnty. Sch. Dist. V. Dist. Ct. (Angalia B.), 141 Nev. Adv. Op. 58 (Nov. 26, 2025), Shahana Polselli

Nevada Supreme Court Summaries

Clark Cnty. Sch. Dist. v. Dist. Ct. (Angalia B.) holds that routine emails on a school district’s server are not accessible education records under federal and state law, unless intentionally maintained as institutional student records.

Oshiro V. Oshiro [State Of Nevada], 141 Nev. Adv. Op. 59 (Nov. 26, 2025), Richard Reid

Nevada Supreme Court Summaries

No abstract provided.

State Of Nevada V. Eighth Judicial District And Kirk, Jr., 141 Nev. Adv. Op. 60 (Nov. 26, 2025), Kerri Richards

Nevada Supreme Court Summaries

No abstract provided.

Gill V. Gill, 141 Nev. Adv. Op. 58 (Nov. 26, 2025), Shahana Polselli

Nevada Supreme Court Summaries

No abstract provided.

Accelerating The Degradation Of Biodegradable Mulch Films In Soil And Compost Environments, Harshal Jayesh Kansara

Theses

The incomplete degradation of biodegradable mulch films (BMFs) in agricultural soils poses environmental challenges, with persistent plastic residues impacting soil health. This dissertation investigates the use of bioaugmentation with P. guariconensis to enhance BMF degradation under laboratory, raised bed, and field conditions. The research focuses on optimizing microbial delivery methods, evaluating the efficacy of drip and spray bioaugmentation techniques, and assessing mass loss as a primary metric for degradation. Laboratory experiments established proof-of-concept by demonstrating enhanced carbon mineralization, weight loss, and fragmentation of BMFs under bioaugmented conditions. These findings were translated to field-scale trials, where bioaugmentation treatments consistently outperformed untreated …

Habitat Determines The Effects Of Wild Ungulate Grazing On Soils: Case Studies From The Iberian Peninsula, Jennifer Adams Krumins, Shih-Chieh Chien, Ramon Perea, Emmanuel Antonio Serrano Ferron, Elena Baraza Ruiz, The Incremento Consortium

Department of Biology Faculty Scholarship and Creative Works

Background and Aims

The bidirectional relationship between plants and their soils can be disrupted by the influence of ungulate grazers. Indeed, herbivores affect plant productivity and above-ground community structure, and plants affect soil health and below-ground community structure. However, the effects of herbivory can be subtle and challenging to address experimentally, even in the case of relatively large ungulate grazers. We attempt to resolve this paradox and experimentally test effects of ungulate grazers in two case studies on the Spanish Iberian Peninsula.

Methods

At the two locations, we experimentally enclosed red deer (Cervus elaphus) at high and hyper …

Heckman V. Live Nation Entertainment: New Rules For Mass Arbitration Companies, Jona Mensch

Cardozo Journal of Conflict Resolution (CJCR) Blog

An interesting new development in alternative dispute resolution has worked its way up the court system in the last few years, as a group of plaintiffs brought a putative class action alleging anticompetitive practices against Live Nation Entertainment and Ticketmaster. Live Nation and Ticketmaster moved to compel arbitration based on Ticketmaster’s Terms of Use, which purported to require that plaintiffs arbitrate claims before a newly created arbitration company—New Era ADR. The Ninth Circuit affirmed the district court’s order denying defendants’ motion to compel arbitration in Heckman v. Live Nation Entertainment, Inc., determining that New Era’s arbitration rules were procedurally …

News You Can Use: Spotting Early Signs Of Vocal Fatigue, Jordan Karnbach

University of Mississippi News

OXFORD, Miss. – It's happened to everyone at some point; your voice simply gives out, whether it's from giving a work presentation or singing along at a concert. But a University of Mississippi researcher has advice on catching early signs of vocal fatigue and tips to prevent straining your voice.

Protective Role Of Salicylic Acid Against Abiotic Stresses In Horticultural Crops: A Review, Faisal Hayat, Xiaoyun Zhang, Mohammed Alyafei, Fareeha Shireen, Ummara Khan, Sumeera Asghar, Sezai̇ Erci̇şli̇, Karthishwaran Kandhan, Mohamed S. Sheteiwy, Yali Zhang, Xiaoyan Lu

Turkish Journal of Botany

Environmental stressors such as drought, floods, salinity, extreme temperatures, and heavy metal toxicity are major threats to horticultural plants because they disrupt plant physiological mechanisms, leading to reduced yield and quality. Salicylic acid (SA) is a plant hormone that regulates various physiological and biochemical functions in plants. Moreover, it regulates hormonal balance, enhances the absorption of essential nutrients, promotes photosynthesis and the production of antistress compounds, and improves stress resistance. This comprehensive review explains several physiological and biochemical activities that are affected by SA under stressful conditions, such as stomatal regulation, antioxidant defense systems, osmotic adjustment and gene expression regulation. …

Quality Improvement Project: Impact Of Simulation Training On The Self-Efficacy Of Registered Nurses During A Code Stroke, Kakeya James

Doctor of Nursing Practice Projects

Self-efficacy levels affect decision-making skills and overall confidence in handling critical situations. However, knowledge gaps often hinder the maintenance of high self-efficacy. (Farčić, et al., 2020). The project site provides limited training opportunities that may not adequately prepare registered nurses with the confidence and skills needed to respond to stroke emergencies, potentially causing delays in patient care and adverse health outcomes. As a result, the quality improvement project aims to examine how simulation-based training impacts registered nurses’ self-efficacy in managing stroke emergencies. The project employed a quasi-experimental pretest/posttest design and was guided by the Plan-Do-Study-Act (PDSA) cycle, the Jeffries Simulation …

Unpacking Alpha In Innovation-Driven Etfs: A Comparative Study Of Artificial Intelligence And Blockchain Funds, Davinder K. Malhotra

School of Business Faculty Papers

This paper evaluates the performance and portfolio role of Artificial Intelligence (AI) and Blockchain exchange-traded funds (ETFs) based on monthly returns from 2010 to 2025. The findings show that both AI and Blockchain ETFs generate positive alpha and high standalone returns but also display considerable drawdown risk. Their weak correlations with each other and with broad indices highlight diversification benefits, particularly when combined with U.S. benchmarks. Portfolio optimization reveals that Global Minimum Variance (GMV) and Tangency portfolios ascribe lower weights to these ETFs, while Risk Parity portfolios have a more balanced exposure, helping to diversify risks. Efficient frontier analysis highlights …

Shift: Master Clinical Decision Making Through A Gamified, Interactive Experience, Stacie Rothfus, Melissa J. Geist

Biennial Convention (CONV)

Shift, a Serious-Gaming simulation, aims to revolutionize simulation education by providing an immersive, interactive platform that replicates real-world scenarios with detailed attention to INACSL standards for evidence-informed excellence in simulation. Simulation is a fundamental part of nursing education, but the traditional approach may not fully cater to the learning preferences of the future nursing workforce. Traditional educational methods often fail to fully engage tech-savvy cohorts who thrive on interactivity, instant feedback, and multimedia content. The project was designed to enhance knowledge acquisition and promote reflection on critical decision-making in an engrossing tech-infused platform compatible with most devices. The modules are …

Escape Room: An Interactive Way To Teach Hypertension To Nurse Practitioner Students, Christine Jewell, Marsha Hellend, Patricia Balogh, Nyssa Amato, Donna Martin

Biennial Convention (CONV)

Background: Hypertension is a significant comorbidity in the United States. Nurse Practitioners (NP) should be familiar with the diagnosis and treatment of hypertension to prevent complications for their patients. An escape room provides a fun and interactive way for NP students to learn and build skills (Friedrich et al., 2020). Escape rooms promote engagement, teamwork, and communication, and allow nurses to make mistakes in a safe environment while also building on their leadership skills (Bashir Raja et al., 2022).

Purpose: The purpose of this activity was to increase Nurse Practitioner (NP) students’ knowledge of treating patients with hypertension …

Supporting The Transition To Practice Through An Undergraduate Academic-Practice Partnership, Marilynn Robayo, Kathleen Ennis

Biennial Convention (CONV)

Purpose Statement: Establishment of academic-practice partnerships with multiple local undergraduate nursing programs has led to a more efficacious transition to clinical practice for newly licensed nurses entering the acute care setting.

Background/Objective: Graduate nurses in their first year of practice often feel unprepared for the reality of clinical practice, contributing to burnout, a global phenomenon. Partnering with local nursing programs to develop realistic clinical experiences and tailoring extern programs and first year entry programs for newly hired graduate nurses has helped one medical center increase nurse retention. Goals of the partnership include: 1) providing clinical experiences that help reduce stress …

Interplay Of Menopause, Coronary Artery Calcium Score And Cardiovascular Disease Risk, Tanisha Mishra, Diksha Sanjana Pasnoor, Murtaza Gandhi, Nida Mohamed, Shaylika Chauhan, Kokou Adompreh-Fia, Kesha Mayank Doshi, Prerana Sevella, Rupak Desai

Abington Jefferson Health Papers

BACKGROUND: Postmenopausal women face an increased risk of cardiovascular disease (CVD) due to estrogen withdrawal, which exacerbates traditional cardiovascular risk factors such as dyslipidemia, glucose intolerance, and hypertension. Coronary Artery Calcium Score (CACS), a well-established marker of subclinical atherosclerosis, has emerged as a key predictor of adverse cardiovascular events. Despite the recognized association between menopause and heightened CVD risk, there remains a paucity of literature exploring the specific role of menopause in influencing CACS and its implications for cardiovascular morbidity and mortality.

AIM: To examine the interplay between menopause, CACS, and cardiovascular health by synthesizing existing literature.

METHODS: A comprehensive …

Reclaiming Relational Pedagogies: The Role Of Talking Circles In Decolonizing Higher Education Classrooms, Veneice Lacy

Faculty Research, Scholarly, and Creative Activity

This article explores the use of Talking Circles as a decolonizing pedagogical practice within higher education, grounded in Indigenous epistemologies and relational worldviews. Drawing on the works of Indigenous scholars such as Graveline, Wilson, Archibald, and Simpson, the article positions Talking Circles not merely as instructional strategies but as ceremonial, spirit-centered pedagogies that resist the Eurocentric hierarchical and individualistic norms of Western academia. Through autoethnographic reflection and student narratives from undergraduate and graduate education courses, the article demonstrates how Talking Circles foster relational accountability, ethical engagement, and transformative learning. By centering oral tradition, reciprocity, and communal learning, Talking Circles reconfigure …

Dna Extrusion Size Determines Pathway Choice During Cag Repeat Expansion, Mayuri Bhatia, Ashutosh S. Phadte, Anna Lakhina, Anthony R. Monte Carloi Iii, Sarah Barndt, Anna Pluciennik

Department of Biochemistry and Molecular Biology Faculty Papers

DNA triplet repeat expansion causes several primarly neurological disorders like Huntington's disease, myotonic dystrophy type 1, and fragile-X related disorders. There is general consensus that recognition of extrahelical extrusions or hairpin-loop structures (formed by strand slippage) by the DNA mismatch repair protein MutSβ leads to repeat expansion by a mutagenic process. By contrast, the FAN1 nuclease attenuates triplet repeat expansion, the molecular basis of which was explained by our recent finding that FAN1 nuclease cleaves and initiates removal of extrahelical extrusions. Here we show that extrusions containing two or more triplet repeats are subject to recognition and processing by either …

Investigating The Neuronal Role Of The Proteasomal Atpase Subunit Gene Psmc5 In Neurodevelopmental Proteasomopathies, Amélie Bosc-Rosati, Tzung-Chien Hsieh, Lise Bray, Marielle Oloudé, Cory Rosenfelt, Marie Pier Scott-Boyer, Victoria Most, Tianyun Wang, Jonas J Papendorf, Charlotte De Konink, Wallid Deb, Virginie Vignard, Maja Studencka-Turski, Thomas Besnard, Anna M Hajdukowicz, Franziska G Thiel, Sophie Wolfgramm, Laëtitia Florenceau, Silvestre Cuinat, Sylvain Marsac, Yann Verrès, Audrey Dangoumau, Léa Poirier, Ingrid M Wentzensen, Annabelle Tuttle, Cara Forster, Johanna Striesow, Richard Golnik, Damara Ortiz, Laura Jenkins, Jill A Rosenfeld, Alban Ziegler, Clara Houdayer, Dominique Bonneau, Erin Torti, Amber Begtrup, Kristin G Monaghan, Sureni V Mullegama, Catharina M L Nienke Volker-Touw, Koen L I Van Gassen, Renske Oegema, Mirjam S De Pagter, Katharina Steindl, Anita Rauch, Ivan Ivanovski, Kimberly Mcdonald, Emily Boothe, Andrew Dauber, Janice Baker, Noelle Andrea V Fabie, Raphael A Bernier, Tychele N Turner, Siddharth Srivastava, Kira A Dies, Lindsay C Swanson, Carrie Costin, Alali Abdulrazak, Rebekah K Jobling, John Pappas, Rachel Rabin, Dmitriy Niyazov, Anne Chun-Hui Tsai, Karen Kovak, David B Beck, May Christine V Malicdan, David R Adams, Lynne Wolfe, Rebecca D Ganetzky, Colleen C Muraresku, Davit Babikyan, Zdeněk Sedláček, Miroslava Hančárová, Andrew T Timberlake, Hind Al Saif, Berkley Nestler, Kayla King, M J Hajianpour, Gregory Costain, D'Arcy Prendergast, Chumei Li, David Geneviève, Antonio Vitobello, Arthur Sorlin, Christophe Philippe, Tamar Harel, Ori Toker, Ataf Sabir, Derek Lim, Mark J Hamilton, Lisa J Bryson, Elaine Cleary, Sacha Weber, Trevor L Hoffman, Anna M Cueto-González, Eduardo F Tizzano, David Gómez-Andrés, Marta Codina-Solà, Athina Ververi, Efterpi Pavlidou, Alexandros Lambropoulos, Kyriakos Garganis, Marlène Rio, Jonathan Levy, Sarah J Langas, Anne M Mcrae, Mathieu K Lessard, Maria Daniela D'Agostino, Isabelle De Bie, Meret Wegler, Rami Abou Jamra, Susanne B Kamphausen, Viktoria Bothe, Lorraine Potocki, Eric Olinger, Yves Sznajer, Elsa Wiame, Michelle L Thompson, Molly C Schroeder, Catherine Gooch, Raphael A Smith, Arti Pandya, Larissa M Busch, Uwe Völker, Elke Hammer, Kristian Wende, Benjamin Cogné, Bertrand Isidor, Jens Meiler, Clémentine Ripoll, Stéphanie Bigou, Frédéric Laumonnier, Peter W Hildebrand, Evan E Eichler, Kirsty Mcwalter, Peter M Krawitz, Florence Roux-Dalvai, Ype Elgersma, Julien Marcoux, Marie-Pierre Bousquet, Arnaud Droit, Jeremie Poschmann, Andreas M Grabrucker, Francois V Bolduc, Stéphane Bézieau, Frédéric Ebstein, Elke Krüger

Faculty, Staff and Students Publications

Neurodevelopmental proteasomopathies are a group of disorders caused by variants in proteasome subunit genes, that disrupt protein homeostasis and brain development through poorly characterized mechanisms. Here, we report 26 distinct variants in PSMC5, encoding the AAA⁺ ATPase subunit PSMC5/RPT6, in individuals with syndromic neurodevelopmental conditions. Combining genetic, multi-omics and biochemical approaches across cellular models and Drosophila, we unveil the essential role of proteasomes in sustaining key cellular processes. Loss of PSMC5/RPT6 function impairs proteasome activity, leading to protein aggregation, disruption of mitochondrial homeostasis, and dysregulation of lipid metabolism and immune signaling. It also compromises synaptic balance, neuritogenesis, and neural progenitor …

Exploring Experiences Of Mental Health Challenges In Under-Represented Young People (Aged 16–24 Years) In England: A Narrative Inquiry Protocol, Rebecca Syed Sheriff, Jason Arday, Rohit Shankar, Roisin Mooney, Louise Chandler, Helen Adams, Lili Z Nagy, Roger Farrell, Daisy Fancourt, Scott Weich, Catherine Henderson, Shaima Hassan, Joe Langley, Kamaldeep Bhui

Peninsula Medical School

Introduction Three-quarters of mental health problems start before the age of 25. However, young people are the least likely to receive mental healthcare. Some young people (such as those from ethnic minorities) are even less likely to receive mental healthcare than others. Long-term impacts of mental health problems include poorer physical health, relationships, education and employment. We aim to elicit the views, experiences and needs of diverse young people (aged 16–24 years), to better understand (1) their experiences of under-representation, mental health and coping, (2) mechanisms that shape mental health trajectories and (3) how online arts and culture might be …

Enhancing Community Health Workers' Knowledge On Childhood Tuberculosis Screening In Nigeria, Rashidat A. Jolaoluwa

Biennial Convention (CONV)

Tuberculosis (TB) poses a significant global health challenge, especially in developing countries like Nigeria, where it disproportionately affects children. This Doctor of Nursing Practice (DNP) study seeks to enhance the knowledge of Community Health Workers (CHWs) and Community Health Extension Worker Students (CHEWs) in screening for childhood TB. Given the urgent need for early detection and intervention, the research focused on equipping CHWs and CHEWs with targeted educational resources. A pretest/posttest design was employed to evaluate changes in knowledge related to childhood TB screening among the participants. Statistical data analysis was conducted to assess improvements and ensure the reliability of …