Digital Commons Network^™

Rapid Evidence Review: Terror Incidents And Perceived Terrorism Risks At Events, Tin L. Nguyen, Callie Vitro, Sarah Schappert, Allison E. Munderloh, Erin M. Kearns

Reports, Projects, and Research

Since the 1972 Munich Olympics, mass gatherings for sport, music, and other entertainment have been viewed as highly vulnerable, culturally significant targets for terrorist attacks. Although research on the enactment and implications of terrorism have become more commonplace, comparatively little research has examined terrorism in the context of organized gatherings and the event venues which host them. Through a rapid evidence review, we summarize empirical research on (a) international incidents of terrorism and (b) perceived terrorism risks at large-scale public events and event venues, as well as (c) their psychological, behavioral, and social/news media effects. This research brief is intended …

Ongoing Recovery Measurements In Kwinana Shelf Seagrass Meadow In Cockburn Sound 2.5 Years Post Impact Phase To Give Greater Confidence In Recovery Data And For Eia Monitoring, Nicole Said, Chanelle Webster, Simone Strydom, Kathryn Mcmahon

Research outputs 2022 to 2026

Executive summary: Understanding the nature of interactions between multiple stressors is essential for assessing their cumulative impacts on seagrasses and for guiding effective management. Current dredging thresholds are based largely on single stressors (light reduction or sediment burial), despite pressures typically co-occurring, and these thresholds may therefore need refinement to account for interactive effects. In addition, recovery times under single and multiple pressures remain a major knowledge gap, further reducing our ability to accurately predict impacts and implement effective management. This need is particularly pressing in regions facing ongoing dredging pressure. Cockburn Sound, which has already lost ~75% of its …

Cutting Through The Fog: Recognising Brain Fog As A Significant Public Health Concern, Darren Haywood, Susan L. Rossell, Nicolas H. Hart

Research outputs 2022 to 2026

Brain fog is a highly common condition that can have significant impacts on quality of life and functioning. Most people will experience a condition, illness, or infection that might result in the development of brain fog. We provide a call to action to minimise the impacts of brain fog.

Health Outcomes Of Sarcopenia: A Consensus Report By The Outcome Working Group Of The Global Leadership Initiative In Sarcopenia (Glis), Charlotte Beaudart, Julian Alcazar, Ivan Aprahamian, John A. Batsis, Yosuke Yamada, Carla M. Prado, Jean Yves Reginster, Dolores Sanchez-Rodriguez, Wee Shiong Lim, Marc Sim, Stephan Von Haehling, Jean Woo, Gustavo Duque

Research outputs 2022 to 2026

The Global Leadership Initiative in Sarcopenia (GLIS) aims to standardize the definition and diagnostic criteria for sarcopenia into one unifying, common classification. Among other actions to achieve this objective, the GLIS has organized three different working groups (WGs), with the WG on outcomes of sarcopenia focusing on reporting its health outcomes to be measured in clinical practice once a diagnosis has been established. This includes sarcopenia definitions that better predict health outcomes, the preferred tools for measuring these outcomes, and the cutoffs defining normal and abnormal values. The present article synthesizes discussions and conclusions from this WG, composed of 13 …

Nanao/Organocatalyat Sio2/4-(2-Aminoethyl)-Morpholine As A New, Reusable, And Efficacious Catalyst For The Synthesis Of Polyhydroquinolines Derivatives And Antibacterially Active Evaluation, Leila Amiri-Zirtol, Zahra Karimi, Javad Farahbakhsh, Ahmad Gholami, Seyedeh Narjes Abootalebi

Research outputs 2022 to 2026

In this study, a new nanocomposite comprising 4-(2-Aminoethyl)-morpholine, an organic catalyst, was prepared on the surface of silica. The absence of metal in the catalyst structure contributes to its environmental friendliness. This novel nanocatalyst was used for multi-component reactions (MCRs). Having a nano size for the composite enhances the contact between the raw materials and the catalytic surface, leading to significant advancement in the reaction. The synthesized composite was identified and evaluated using FT-IR, EDX, EDX-Mapping, TGA, XRD, BET, TEM, and FE-SEM analysis. The characteristic analysis confirmed the synthesis of both nano-silica/4-(2-Aminoethyl)-morpholine catalyst and polyhydroquinoline. The composite’s catalytic properties for …

Nurses’ And Midwives’ Job Satisfaction And Retention During Covid-19: A Scoping Review, Laura Hynes, Sadie Geraghty, Sheena Mcchlery, Aisling Smyth, Reeti Brar, Karen Clark-Burg

Research outputs 2022 to 2026

Background: The COVID-19 pandemic focused attention on the previously well-documented world-wide shortage of nurses and midwives. The pandemic accentuated this crisis, which resulted in nurses and midwives questioning their roles and their careers. The impact of the pandemic on job satisfaction and the intention of nurses and midwives to stay has not been adequately explored. Aim: The aim of this scoping review was to identify and map the literature that describes the intrinsic and extrinsic factors that influenced nurses’ and midwives’ job satisfaction and intent to stay or leave their employment or profession during the COVID-19 pandemic. Method: This scoping …

Photocatalytic Performance Of N-Doped Ti3o5 Nano-Catalyst For Phenolic Compounds Removal From Industrial Wastewaters, Mehdi Narimani, Maryam Gonbadi, Mahsa Navabi, Fatemeh Khezri-Shooshtari, Amin Ale Ebrahim, Mohammad Mahdi Zerafat

Research outputs 2022 to 2026

This study is focused on the synthesis and evaluation of TiO2 and N-doped Ti3O5 for the photocatalytic degradation of phenol as a noxious substance commonly present in the industrial process effluents with harmful effects on human and the environment. The research addresses the critical environmental challenge posed by phenol-contaminated effluents from petrochemical industries. Leveraging Response Surface Methodology with Box-Behnken design, 17 experiments were conducted to analyze the impact of independent variables such as photo-catalyst dosage, pH, and irradiation time on degradation efficiency. Notably, the average crystallite sizes were determined as 20 nm for TiO2 and 58.3 nm for N-doped Ti3O5. …

Summarizing Attributable Factors And Evaluating Risk Of Bias Of Mendelian Randomization Studies For Alzheimer’S Dementia And Cognitive Status: A Systematic Review And Meta-Analysis, Xiaoni Meng, Xiaochun Li, Meiling Cao, Jing Dong, Haotian Wang, Weijie Cao, Di Liu, Youxin Wang

Research outputs 2022 to 2026

Background: No effective treatment is available to delay or reverse the onset and progression of Alzheimer’s dementia (AD). Mild cognitive impairment, a clinical state between normal aging and AD, may offer the proper window for AD intervention and treatment. This systematic review aimed to summarize evidence from Mendelian randomization (MR) studies exploring factors attributable to AD and related cognitive status and to assess its credibility. Methods: We searched PubMed, Embase, MEDLINE, and the Cochrane Library to identify MR studies investigating the associations between any factor and AD and related cognitive status. The risk of bias in MR studies was evaluated …

State Of Stroke Rehabilitation In Australia: A Who Stars Assessment To Identify Strengths And Gaps Across Policy, Practice And Funding, Lauren J. Christie, Erin Godecke, Maddison Smith, Katharine Scrivener, Kelvin Hill, Joosup Kim, Maria Crotty, Dominique A. Cadilhac, Angela Dos Santos, Natasha A. Lannin

Research outputs 2022 to 2026

Purpose of Review: Rehabilitation following stroke is a complex series of assistive and catalytic interventions enabling a survivor to recover and adapt to their stroke. To achieve adaptation, rehabilitation should supplement healthcare across the continuum, however comprehensive evidence on the provision of stroke rehabilitation in Australia is lacking. The aim of this paper was to describe stroke rehabilitation provision, collecting data using the World Health Organisation (WHO) template for rehabilitation information collection (TRIC). Data were analysed descriptively to complete the Systematic Assessment of Rehabilitation Situation (STARS) assessment. Recent Findings: Challenges include inadequacies in reporting and poor data integration between state- …

Motivation And Productivity Of Female Employees In China With Scoliosis Pain, Shauna-Kay Reeves

Walden Dissertations and Doctoral Studies

A scoliosis diagnosis can impact an individual’s work performance, particularly if there is a lack of proper ergonomics or workplace accommodations that might lead to increased pain and discomfort. Organizational leaders must understand this impact as an indicator of employee motivation and productivity. The purpose of this qualitative, interpretative phenomenological analysis was to explore the lived experience of female employees in China with scoliosis pain and its impact on their motivation and productivity. The theoretical foundations used in this study were the job demands-resources model and the self-determination theory. The participants consisted of eight female employees with scoliosis pain working …

A Stochastic Framework For Hosting Capacity Analysis Of Residential Distribution Systems With Solar Photovoltaic And Electric Vehicle Adoption, Sina Ibne Ahmed

Theses and Dissertations

The rise of distributed generation and the electrification of transportation are driving fundamental changes in the electric grid. The growing adoption of electric vehicles and solar rooftops introduces significant uncertainty in demand patterns, posing new challenges for the operation of distribution systems. Residential distribution systems are particularly vulnerable to the impacts of residential solar photovoltaics (PV) generation and electric vehicle charging, as they introduce significant variability and localized stress on the grid. To ensure reliable and efficient operation, utilities must account for the long-term growth of these technologies in their planning processes. While substantial progress has been made in assessing …

Thermal Desorption-Pyrolysis Gas Chromatography-Mass Spectrometry Method Development For The Determination Of Wood Preservatives, Nafisa Bala

Theses and Dissertations

A thermal desorption-pyrolysis gas chromatography with mass spectrometric detection (TD-Pyr-GC-MS) method was developed, enabling a comprehensive analysis of preservatives as well as native wood constituents in treated wood. The developed method is based on thermal desorption, i.e., extraction of wood preservatives, followed by pyrolysis to investigate changes in the occurrence of characteristic wood building blocks (e.g., guaiacol derivatives). We implemented a combined MS data acquisition (i.e., SITI) consisting of selected ion monitoring (SIM) and total ion current (TIC), allowing for low limits of detection of preservatives in SIM mode and TIC detection of any evolving species. The matrix detection limits …

The Role Of C-X-C Chemokine Receptor Type 5 (Cxcr5) On Sex-Dependent Neurobehavioral Changes In The Sub Clinically Sensitized Individuals With Repeated Allergen Exposure, Dilini Vimarshani Ekanayake Ekanayake Mudiyanselage

Theses and Dissertations

Food allergen consumption has been suspected to influence mood and behavior in individuals who are sensitized but tolerant to the food. Using a mouse model of subclinical cow’s milk allergy (CMA), we previously showed that C57BL/6J mice sensitized to β-lactoglobulin (BLG, Bos d 5) exhibited elevated BLG-specific IgE levels even without observable allergic reactions, suggest developing immune responses towards the allergen. We also observed elevated cytokine and chemokine levels, astrogliosis and cortical demyelination along with behavioral changes such as anxiety-like and depression-like behavior after consuming a whey-containing diet for two weeks. Furthermore, we demonstrated the possible immune cell infiltration and …

Evaluating Hail Spectrometer Data Quality And Uncertainty For Calculating Radar Reflectivity Factor, James Klinman

Theses and Dissertations

Reliable in situ measurements are essential for accurately forecasting and nowcasting hailstorms, as they provide insight into storm processes, improve predictions that protect public safety, and help assess potential damage to agriculture and infrastructure. This study evaluates the reliability of in situ hail measurements from the T-28 aircraft’s Hail Spectrometer and assesses their feasibility for radar reflectivity validation and parameterization. Data from 14 flights across five field campaigns were analyzed, focusing on comparisons between one-dimensional (1D) 1-Hz accumulated particle counts and two-dimensional (2D) particle images produced by the Hail Spectrometer. The 2D data were processed using the System for Optical …

Dynamic Wellbore-Integrity Framework For Post-Blowout Capping Of Offshore Wells, Abdelhakim Khouissat

Theses and Dissertations

In the aftermath of a blowout, a well undergoes a period of unrestricted fluid discharge (de facto primary recovery) followed by pressure buildup after its shut-in, which can adversely impact wellbore integrity. The quintessential example is Union Oil’s 1969 “A-21” well blowout in California’s Santa Barbara Channel, where seafloor-broaching incidents (oil “boilups”) kept taking place from the sides of the well following several failed well-capping attempts, until reservoir depletion eventually allowed a successful shut-in.Analytical and numerical reservoir depletion models are coupled with near-wellbore geomechanics to quantify yardsticks related to the post-blowout discharge utilized to indicate dangers for underground blowouts, in …

Of Birds And Beef: Expanding The Knowledge Of Rotational Grazing Systems On Grassland Bird Productivity In North Dakota, Taylor James Linder

Theses and Dissertations

Cattle grazing is one of the main economic contributors driving grassland ecosystem existence across the landscape. Cattle grazing can impact a variety of aspects of grassland ecosystems functions, including which wildlife species use them and in what ways. Given the drastic declines in grassland passerines, it is especially important to understand how different grazing practices affect critical population metrics such as reproductive success, clutch size, and number of fledglings. There is a wealth of research on grassland passerine reproductive in response to grazing systems throughout North America; however, most of the existing literature studies more traditional, longer rotational (LR) grazing …

Identity Formation Through The Lived Experiences Of Immigrant Muslim High School Students, Badera Muhanna

Theses and Dissertations

The growing number of Muslim students enrolled in U.S. public schools necessitates a more comprehensive understanding of their unique experiences within their educational environments. This phenomenological qualitative study investigated Muslim students' perceptions of their lived experiences in a high school in the Northern Great Plains of the United States. Six Muslim students in their junior and senior years were selected to participate in semi-structured interviews. Through the lens of Bronfenbrenner’s ecological systems theory, this study aimed to deepen understanding of how Muslim students develop their sense of identity and the factors that contribute to this development. The findings revealed that …

Impacts Of Intensifying Wildfires On Boreal Forest Ecosystems: Exploring Forest Regeneration, Wildlife Habitats, Carbon Storage, And Engineering Solutions, Mckenzie Belle Schewe

Theses and Dissertations

Wildfire activity across Alaska’s boreal forests has intensified in severity and frequency in recent decades, altering one of Earth’s most significant sources of carbon sequestration (Pan et al, 2011). This thesis examines how wildland burns influence post-fire carbon sink capacities and vegetation recovery near Fairbanks, Alaska. Three fire sites were selected to represent distinct successional stages: the 2006 Parks Highway Fire, the 2013 Stuart Creek 2 Fire, and the 2022 Clear Fire. Each site was evaluated through a combination of remote sensing analysis, LiDAR-derived canopy height data, and field measurements collected within each burn perimeter, developing a replicable framework for …

Exploratory Study Of Relationships Between Law Students' Well-Being, Academic Success, And Perceptions Of Passing The Bar Exam And Admission, Pamela Shea

Theses and Dissertations

This study explores the experiences of law students that impact their perception of being prepared for the Bar Exam and Bar admission. Analyzing the stressors law students face during law school reveals the essential need to incorporate the eight dimensions of well-being into curricular, co-curricular, and extra-curricular activities for students to flourish as they prepare for post-graduation success. Using the data from the 2021 Survey of Law Student Well-Being, which surveyed 5,865 law students from thirty-nine ABA-accredited law schools, a three-factor model was created to group students’ concerns into academic and health concerns, social and environmental concerns, and well-being behavioral …

Experimental And Computational Insights Into Reservoir Rock Mechanics And Petrophysical Properties, Prasad Pothana

Theses and Dissertations

This dissertation investigates the influence of stress, mineralogy, and microstructure on the elastic and transport properties of reservoir rocks. A multi-scale framework integrating laboratory measurements, petrophysical inversion, and discrete-element simulations is developed to quantify the stress-dependent behavior of heterogeneous sedimentary formations relevant to hydrocarbon production and CO2 sequestration.

Core-scale experiments quantify velocity–effective stress and permeability–effective stress relationships in tight siliciclastic and mixed lithologies. Results demonstrate that pore-throat collapse and microcrack closure under confining stress cause systematic reductions in permeability and acoustic velocities. The derived empirical functions provide predictive capability for estimating in-situ stress effects on reservoir performance and time-lapse seismic …

Is Artificial Intelligence Really Taking Our Jobs?, Francesca A. Strom

Undergraduate Theses and Capstone Projects

This paper studies how artificial intelligence has reshaped occupational opportunities in the United States by analyzing changes in employment, median wages, and wage inequality across all occupations from 2014 through 2024. Using a difference-in-differences framework, I compare occupations associated with AI-related tasks to those not directly exposed to generative AI, with particular attention to the structural break introduced by the mainstream release of generative AI tools in 2022. The results show no statistically significant decline in employment among AI-exposed occupations, indicating that early adoption did not lead to measurable job displacement. Instead, the strongest effects appear in wage inequality. Among …

Evaluating The Effect Of Visual Data On Multimodal Artificial Intelligence Diagnostic Performance, David W Bates

Faculty, Staff and Students Publications

No abstract provided.

Racial And Ethnic Associations With Interstitial Lung Disease And Healthcare Utilization In Patients With Systemic Sclerosis, Paul F Dellaripa, Gary Matthew Hunninghake, David W Bates

Faculty, Staff and Students Publications

Objective: Racial and ethnic differences in presentation and outcomes have been reported in SSc and SSc-interstitial lung disease (ILD). However, prior studies have limited diversity. We aim to evaluate if there are racial/ethnic differences associated with ILD, time intervals between SSc and ILD, and emergency department (ED) visit or hospitalization rates.

Methods: Clinical and sociodemographic variables were extracted for 756 patients with SSc from longitudinal health records in an integrated health-system. Logistic regression models analysed the association of covariates with ILD and age at SSc-ILD. Healthcare outcomes were analysed with complementary log-log regression models.

Results: Overall, 33.7% of patients in …

A Pilot Study Investigating The Impact Of Cigarette Smoking On Oral Nitrate-Reducing Bacteria Within The Oral Microbiome, Tomas L Nicholas, Raul Bescos, Amazon Doble, Katie Muddiman, Paul Kellett, Abish S Stephen, Lisa Du Toit, Robert Witton, Zoë Ls Brookes

Peninsula Dental School

ObjectiveTo evaluate the impact of cigarette smoke on the activity and abundance of oral nitrate reducing bacteria (ONRB) in vivo and in vitro.Materials and MethodsAn observational study comprising of eleven cigarette smokers and thirty-one non-smokers. A saliva and nitrate-rinse sample were collected from each participant to analyse salivary biomarkers and the activity and abundance of ONRB in vivo. Additionally, the effect of cigarette smoke on the nitrate-reducing activity of four Rothia species was investigated in vitro.ResultsThe beta diversity of the oral microbiome was significantly different between smokers and non-smokers (P = 0.0063). Neisseria flavescens and Actinomyces oris were significantly higher …

Nortriptyline Inhibits Lysosomal Exocytosis-Mediated Sasp During Gastric Cancer Progression Via Targeting Hoxa1-Pitx2 Phase Separation, Xiaojing Wang, Wanju Jiao, Xiaolin Wang, Jiaying Qu, Bosen Zhao, Shunchen Zhou, Qiangsong Tong, Liduan Zheng

Faculty, Staff and Students Publications

Lysosomal exocytosis, a calcium-dependent secretory process, facilitates extracellular release of cargos that promote cancer progression, though its regulatory pathways and therapeutic strategies are poorly understood. Herein, using combined transcriptomic and proteomic approaches, we identify homeobox A1 (HOXA1) as a functional partner of paired like homeodomain 2 (PITX2) within biomolecular condensates forming via liquid-liquid phase separation. Mechanistically, HOXA1-PITX2 complex facilitates the expression of mucolipin 1 (MCOLN1) and RAS-related protein Rab-3A (RAB3A), which drive lysosomal exocytosis of galectin-1 (LGALS1) and insulin like growth factor binding protein 7 (IGFBP7) from senescent gastric cancer cells. This process potentiates AKT activation and epithelial-mesenchymal transition, accelerating …

Daptomycin Resistance Of Corynebacterium Jeikeium Due To Pgsa Gene Mutation Acquired During Daptomycin Treatment In A Patient With Infective Endocarditis, Shinya Yamamoto, Koh Okamoto, Ayano Nakazato, Yoshimi Higurashi, Shuhei Matsumoto, Junji Tokushige, Arika Shimura, Takeya Tsutsumi

Faculty, Staff and Students Publications

Daptomycin is an alternative agent for invasive infections caused by Corynebacterium species in patients with intolerance to vancomycin. Although it has recently been recognized that treatment failure with daptomycin due to the emergence of resistant strains during treatment is not uncommon in Corynebacterium striatum infections, it has been unclear whether there is a similar risk in Corynebacterium jeikeium infections. In the presenting case, daptomycin treatment for C. jeikeium endocarditis in a liver transplant recipient with neutropenia failed due to the rapid emergence of the resistant strain. Whole-genome sequencing analysis of blood culture isolates confirmed that a mutation in the pgsA …

Healthy Aging And Aging-Related Kidney Diseases: Lessons From Centenarians, Minami Matsumoto, Ryo Yamada, Takahisa Yoshikawa, Motoko Yanagita

Faculty, Staff and Students Publications

The world's population is aging, and age-related diseases such as neurodegenerative, cardiovascular, and metabolic disorders are rapidly increasing. The field of nephrology is expected to be profoundly influenced by the demographic trend toward increased life expectancy. Consequently, promoting healthy aging has emerged as a critical priority for both individuals and society. Centenarians (those who have reached the age of 100) exemplify exceptional longevity and are regarded as a model of healthy aging. They are distinguished by a notable resistance to risk factors commonly associated with cardiovascular diseases, such as diabetes and dyslipidemia. Remarkably, although centenarians exhibit a high prevalence of …

Health-Related Quality Of Life After Neonatal Treatment Of Symptomatic Tetralogy Of Fallot: Insights From The Congenital Cardiac Research Collaborative, Bryan H Goldstein, Christopher J Petit, Yun Zhang, Courtney E Mccracken, Athar M Qureshi, Caren S Goldberg, Jennifer C Romano, Mark A Law, Jeffery J Meadows, Shabana Shahanavaz, Sarosh P Batlivala, Shiraz A Maskatia, Asaad Beshish, Michael L O'Byrne, R Allen Ligon, Kathryn O Stack, Hala Q Khan, Shalin Parekh, Dawn L Ilardi

Faculty, Staff and Students Publications

To evaluate the association between initial management strategy of neonatal symptomatic Tetralogy of Fallot (sTOF) and later health-related quality of life (HRQOL) outcomes. We performed a multicenter, cross-sectional evaluation of a previously assembled cohort of infants with sTOF who underwent initial intervention at ≤ 30 days of age, between 2005 and 2017. Eligible patients’ parents/guardians completed an age-appropriate Pediatric Quality of Life Inventory, a Pediatric Quality of Life Inventory Cardiac Module Heart Disease Symptoms Scale, and a parental survey. The association between treatment strategy and HRQOL was evaluated, and the entire sTOF cohort was compared to published values for the …

The Association Between Condom Use Self-Efficacy And Condom-Decision Abdication Among College Students, Sarah E Woolf-King

Faculty, Staff and Students Publications

Objective: Condomless sex and its related consequences are a persistent problem on college campuses in the United States. This study aimed to examine the association between condom use self-efficacy and condom-decision abdication among college students, and whether this association was moderated by gender.

Participants & methods: Undergraduate college students (N = 212; 50.5% female) were recruited via Amazon Mechanical Turk as part of a larger online study that examined normative feedback for condom use.

Results: The association between condom use self-efficacy and condom-decision abdication was significantly moderated by gender (B = -0.07, p < .001), such that condom use self-efficacy was associated with condom-decision abdication in college women (B = -0.05, p < .005) but not in college men (B = .02, p = .18).

Conclusion: Findings from this study suggest that …

Resilience And Childhood Trauma In Mood Disorders: Psychopathological Implications And Treatment Response, Alessio Simonetti, Alexia Koukopoulos, Delfina Janiri, Lorenzo Moccia, Marianna Mazza, Mauro Pettorruso, Giovanni Martinotti, Gabriele Sani

Faculty, Staff and Students Publications

Background and aim: Childhood trauma is a key risk factor for mood disorders and is associated with greater clinical severity, while resilience may act as a protective factor. This study investigates how childhood trauma and resilience interact to shape psychopathology and treatment response in patients with major depressive disorder (MDD) and bipolar disorder (BD).

Methods: The study included 669 participants: 569 patients (380 MDD, 189 BD) and 100 healthy controls (HC). Symptom severity was assessed using standardized scales, with follow-up evaluations of depressive symptoms at six months. All participants completed the Childhood Trauma Questionnaire (CTQ) and Connor-Davidson Resilience Scale (CD-RISC). …