Digital Commons Network^™

Sztuczna Inteligencja W Systemach Informatycznych Zarządzania W Środowisku Procesowym, Małgorzata Oleś-Filiks

Monografie/Monographs

Współczesne systemy informacyjne zarządzania wraz z procesami biznesowymi odgrywają kluczową rolę w funkcjonowaniu organizacji, wspierając zarówno codzienne operacje, jak i podejmowanie strategicznych decyzji. Monografia przybliża problematykę integracji sztucznej inteligencji z wybranymi typami systemów informatycznych zarządzania ze szczególnym uwzględnieniem Business Process Management jako środowiska sprzyjającego implementacji sztucznej inteligencji jako narzędzia wspomagającego sterowanie, analizę i optymalizację procesów biznesowych. Szeroko prezentuje m.in. typy systemów informacyjnych zarządzania, w których wdrożenie AI przynosi największe korzyści, ze szczególnym uwzględnieniem Business Process Management jako środowiska, w którym sztuczna inteligencja może być skutecznie osadzona jako komponent sterujący i analityczny.

Artificial Intelligence in IT Management Systems in a Process …

Finanse Cyfrowe: Tesserakt, Jakub Górka

Monografie/Monographs

Monografia przybliża sposób, w jaki technologie cyfrowe (m.in. sztuczna inteligencja, big data, blockchain, chmura obliczeniowa) oddziałują na usługi finansowe oraz wspierają rozwój innowacyjnych modeli biznesowych podmiotów świadczących usługi finansowe, oddziałują na struktury rynkowe czy transformują rynki finansowe oraz jakie generują konsekwencje społeczno-ekonomiczne.

Digital Finance: Tesseract

The monograph presents how digital technologies (i.e. artificial intelligence, big data, blockchain, cloud computing) affect financial services and support the development of innovative business models of financial service providers, influence market structures, transform financial markets, and generate socio-economic consequences.

Community College Student Admissions Experiences, Jeremy D. Loy

Electronic Theses and Dissertations

Community college students have always faced barriers to going to college and getting their degrees. Much of the research centers on the completion of their degrees. The purpose of this qualitative, phenomenological study was to understand the experiences of community college students during enrollment. To understand how community college students experience the enrollment process, the study used phenomenology to hear the experiences of students through semistructured interviews. Findings showed that three broad themes emerged from this research. First, students felt both nervous and uncertain about college, but they also recognized the importance of college to improve their lives. Second, students …

Principals’ Perceptions Of Their Preparedness To Facilitate And Support Technology Integration In Schools: A Case Study Of Four Rural Texas Principals, Christina J. Campbell Ed.D.

Electronic Theses and Dissertations

School administrators face the challenge of leading technology integration that provides meaningful learning opportunities to prepare students for 21st-century skills and careers. Research has shown that administrative leadership support, behaviors, assumptions, and policies impact technology integration in the classroom. The International Society for Technology in Education (ISTE) standards include guidelines for education leaders and their role in supporting educators using technology. However, leaders underestimate the impact of their leadership on effective use in the classroom. The purpose of this qualitative case study was to explore the perceptions of South Texas rural public school principals working in Chapman Independent School District …

The 4-Day School Week: Impacts On Rural Texas School Districts, Geoffery Bowdoin

Electronic Theses and Dissertations

This study examined how school administrators, teachers, and parents in rural Texas districts view the effects of the 4-day school week. Across Texas, a growing number of districts have adopted shorter calendars to address teacher shortages, boost morale, and manage tight budgets. The goal of this research was to gain a clearer understanding of how this schedule shift influences student performance, district finances, and teacher recruitment and retention. The study followed a qualitative descriptive approach. Data were collected through two means. Semistructured interviews were conducted with 12 school administrators, while 29 teachers and 42 parents completed surveys. Research participants came …

Freshwater Turtle Assemblages And Densities In Agricultural Ditches And Aquaculture Ponds Of Eastern Arkansas, Andrhea D. Massey, John D. Willson, Brett A. Degregorio

Biological Sciences Faculty Publications and Presentations

The Mississippi Alluvial Plain (MAP) of Arkansas is a landscape where many wetlands have been altered for use as aquaculture ponds or agricultural ditches. Commercial harvest of freshwater turtles within the MAP is not restricted or limited, with reported harvest numbers for 2019 alone exceeding 4000 for spiny softshell turtles (Apalone spinifera) and 39,000 for red-eared sliders (Trachemys scripta elegans). Herein, we attempt to provide baseline estimates of freshwater turtle densities and community composition in aquaculture ponds and agricultural ditches of eastern Arkansas, the habitat types most frequently trapped by commercial harvesters. We used a capture-mark-recapture approach over 3 summers …

Estimation Of 3d Facial Dynamics With Nonlinear Filters For Position Tracking, Thoa Thieu, Roderick Melnik

School of Mathematical & Statistical Sciences Faculty Publications

This study presents a comparative evaluation of three nonlinear state estimation filters, the Extended Kalman Filter (EKF), Unscented Kalman Filter (UKF), and Particle Filter (PF), for the task of 3D facial landmark tracking. Using a publicly available dataset, we assess each filter's performance under both deterministic (noise-free) and stochastic (noisy) conditions. Metrics such as mean squared error (MSE), convergence rates of state and covariance estimates, and consistency over time are used to quantify tracking performance. Results show that the EKF consistently outperforms the UKF and PF, achieving faster convergence and lower estimation error, particularly in scenarios characterized by mild nonlinearity. …

Impact Of Exercise In Patients With Pancreatic Cancer Across Different Treatment Phases: A Systematic Review, Linda Toniolo, Anita Borsati, Cristina Crespo-Garcia, Diana Giannarelli, Christian Ciurnelli, Gloria Adamoli, Lorenzo Belluomini, Ilaria Trestini, Daniela Tregnago, Federico Schena, Robert U. Newton, Salvatore Paiella, Roberto Salvia, Michele Milella, Sara Pilotto, Alice Avancini

Research outputs 2022 to 2026

Background: With a dismal prognosis of 8–10 % 5-year survival since diagnosis, pancreatic cancer remains one of the most aggressive oncological diseases. This work aimed to evaluate the effects of exercise medicine on safety and feasibility, physical fitness, body composition, patient-reported outcomes, and clinical outcomes across different treatment phases in patients with pancreatic cancer. Method: PubMed, Cochrane, and Scopus databases were systematically screened to identify single-arm studies and randomized/non-randomized controlled trials investigating a physical exercise intervention in patients with pancreatic cancer. The RoB 2 and ROBINS-I tools were used to evaluate study quality for randomized and non-randomized studies, respectively. Qualitative …

Exploring The Experiences And Needs Of Chinese Older Adults And Their Family Caregivers, Yu Huang

Research outputs 2022 to 2026

This multi-generational research project represents an academic partnership between Edith Cowan University (ECU) and Chung Wah Community Care (CWCC), conducted from February to August 2025. Through CWCC's established community participation programs, this collaboration provided both a rich platform for community engagement and an accessible entry point for an ECU Research Internship to collect and analyse in-depth data on the "homing" experiences of Chinese elderly immigrants in Australia.

The study employed a mixed-methods design, engaging 162 survey participants and 15 interview participants across CWCC's two service locations (Balcatta Hub and Willetton Hub) and one well-aged group of name as Evergreen College. …

De Novo Annotation Reveals Transcriptomic Complexity Across The Hexaploid Wheat Pan-Genome, Benjamen White, Thomas Lux, Rachel Rusholme-Pilcher, Angéla Juhász, Gemy Kaithakottil, Susan Duncan, James Simmonds, Hannah Rees, Jonathan Wright, Joshua Colmer, Sabrina Ward, Ryan Joynson, Benedict Coombes, Naomi Irish, Suzanne Henderson, Tom Barker, Helen Chapman, Leah Catchpole, Karim Gharbi, Utpal Bose, Moeko Okada, Hirokazu Handa, Shuhei Nasuda, Kentaro K. Shimizu, Heidrun Gundlach, Michelle L. Colgrave

Research outputs 2022 to 2026

Wheat is the most widely cultivated crop in the world, with over 215 million hectares grown annually. The 10+ Wheat Genomes Project recently sequenced and assembled to chromosome-level the genomes of nine wheat cultivars, uncovering genetic diversity and selection within the pan-genome of wheat. Here, we provide a wheat pan-transcriptome with de novo annotation and differential expression analysis for these wheat cultivars across multiple tissues. Using the de novo annotations we identify cultivar-specific genes and define the core and dispensable genomes. Expression analysis across cultivars and tissues reveals conservation in expression between a large core set of homeologous genes, in …

Partners, Coordinators And High-Level Leaders’ Perspectives On A Consumer And Community Involvement Program In Australia: A Qualitative Evaluation Using Template Analysis, James Smith, Howard Lance, Susan Hayes

Research outputs 2022 to 2026

A Consumer and Community Involvement program located in Australia supports consumers, community members and researchers to work in partnership with health research priorities, policy and practice. The program is positioned to enhance Consumer and Community Involvement (CCI) at individual, organisational, and system levels. Partners are key to the program’s development, growth and sustainment. This study explored various partner perspectives on their involvement within the CCI program, including individuals (consumers, researchers) organisations (universities, medical research institutes) and the system level (funding organisations) alongside CCI program coordinators (delivering the program) and high-level leaders (decision-makers/executive leaders/directors). Data were collected via two focus groups …

Rac1 In Gastric Cancer: A Molecular Driver Of Invasion, Emt, And Therapeutic Resistance, Jianwen Li, Yahong Zhu, Ruifeng Duan, Yueli Tian, Xingang Li, Ying Song

Research outputs 2022 to 2026

Gastric cancer (GC) ranks as the fifth most common cancer worldwide and is the third main cause of cancer-related mortality, posing a substantial burden to global public health. Research suggests that targeted therapy and immunotherapy may become more effective treatment options for advanced, unresectable, or metastatic gastric cancer. Ras-related C3 botulinum toxin substrate 1 (Rac1), a small GTP-binding protein within the Rac subfamily of the Rho GTPase family, is a critical molecule that promotes cancer cell invasion and metastasis by regulating signal transmission and promoting cell polarity. It has emerged as a key driver of tumor development and metastasis in …

Therapeutic Potential And Enhanced Bioactivity Of Ficus Carica (Fig) Fruit: Exploring Bioactive Compounds And Nano-Additive Synergies, Mst Sumya Yeasmin, Shamima Abdul Rahman, Waheedah Abdul Hakeem, Tarek Abedin, Mohammad Nur-E-Alam

Research outputs 2022 to 2026

The present investigation deals with the phytochemical, anticancer, antioxidant, anti-inflammatory, antidiabetic, and Anti-constipation activities of Ficus carica (FC) fruit. The phytochemical analysis of FC fruit has revealed a rich array of bioactive compounds, highlighting the fruit's complex and diverse natural chemistry together with some secondary metabolites that contribute to its high antioxidant activity which was evident from 1-Diphenyl-2-picrylhydrazyl (DPPH), 2,2′-Azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) and Ferric reducing power (FRAP) assays. Fruit extracts of FC demonstrated anticancer activity against MCF-7 breast cancer, U2OS osteosarcoma, HepG2 liver cancer, and Huh7it liver cancer cell lines. The anti-inflammatory activity of FC fruit is attributed to steroids …

Trends And Determinants Of Early Neonatal Mortality In Ethiopia: Evidence From The Ethiopian Demographic And Health Survey Data, Tsion Mulat Tebeje, Beminate Lemma Seifu, Yordanos Sisay Asgedom, Kusse Urmale Mare, Zufan Alamrie Asmare, Hiwot Altaye Asebe, Abdu Hailu Shibeshi, Afework Alemu Lombebo, Kebede Gemeda Sabo, Bezawit Melak Fente, Bizunesh Fantahun Kase

Research outputs 2022 to 2026

Background: Early neonatal mortality (ENM) accounts for three-fourths of all neonatal deaths and one-third of overall child mortality. While previous studies have primarily focused on neonatal and under-five mortality, ENM has received comparatively less attention. This study aims to address this gap by analyzing trends and identifying factors associated with ENM in Ethiopia. Methods: Data from the Ethiopian Demographic and Health Survey (EDHS) conducted between 2005 and 2016 were analyzed, comprising a total weighted sample of 22,310 participants. To account for the hierarchical structure of the EDHS data, a mixed-effects binary logistic regression model was applied to identify associated factors. …

Understanding Regional, Rural And Remote Teacher Wellbeing Narratives Through Podcasting: A Qualitative Analysis Of Multiple Stakeholder Perspectives, Narelle Lemon, Marnie Harris

Research outputs 2022 to 2026

Highlighting the strengths-based approaches to supporting pre-service teachers, this study explores the diverse and effective wellbeing and self-care practices embedded within regional, rural and remote (RRR) professional experience placements. Drawing on rich qualitative data from podcast conversations, the research emphasises the value of contextually responsive support. Inductive thematic analysis revealed five key enablers of wellbeing: structured support systems, personal wellbeing management, community integration, environment adaption, and professional resilience. These interconnected themes demonstrate that wellbeing in RRR contexts is nurtured through both formal frameworks and individual agency, as well as through meaningful engagement with place and community. Podcasting as method enabled …

A Bayesian Optimisation With Segmentation Approach To Optimising Liquid Handling Parameters, Estefania Yap, Viet Huynh, Calvin Vong, Peter Vogel, Viv Louzado, Thomas Barnes, Buser Say, Michael Burke, Dana Kulić, Aldeida Aleti

Research outputs 2022 to 2026

The automation of liquid handling has become integral in speeding up pharmaceutical development for faster drug development and more affordable treatments. However, the optimal parameters which define the aspirate and dispense procedures vary between liquids and liquid volumes, limiting transfer accuracy and precision. Even state-of-the-art liquid handling devices offer predefined parameters for only a handful of liquids and volumes, resulting in novel parameter sets being defined via a manual, time-consuming process. In this study, we propose an experimental framework for automating the optimisation of liquid class parameters for arbitrary liquids. Within our framework, we propose an optimisation and segmentation algorithm, …

Application Of Plastic Waste As A Sustainable Bitumen Mixture—A Review, Nuha S. Mashaan, Thakur Chamlagai

Research outputs 2022 to 2026

Plastic waste is growing rapidly, while asphalt binders remain heavily reliant on petroleum bitumen. Incorporating recycled plastics into bitumen can divert waste and enhance pavement performance. This review compiles 251 experimental records from 56 studies to evaluate how plastic type, dosage, and processing conditions affect softening point, penetration, and viscosity. Across studies, plastics (PET, LDPE/HDPE/LLDPE, PP, and hybrids) consistently stiffen binders, reducing penetration and increasing softening point and viscosity, thereby improving rutting resistance while potentially raising mixing/compaction demands. Using grouped cross-validated machine-learning models (median baseline, ridge, random forest, XGBoost), we quantify the predictability of binder properties and show that nonlinear …

Global Estimates Of Seagrass Blue Carbon Stocks In Biomass And Net Primary Production, Enric Gomis, Simone Strydom, Nicole R. Foster, Diana Montemayor, Miguel A. Mateo, Eduard Serrano, Karina Inostroza, Roisin Mccallum, Anna Lafratta, Chanelle L. Webster, Caitlyn L. O’Dea, Nicole E. Said, Natasha Dunham, Rachele Bernasconi, Axel Werner, Federico Vitelli, Viena Puigcorbé, Alexandra D’Cruz, Cristian Salinas, Kathryn M. Mcmahon, Glenn A. Hyndes, Paul S. Lavery, Albert Pessarodona, Carlose M. Duarte, Oscar Serrano

Research outputs 2022 to 2026

Seagrass meadows play a key role in the global carbon cycle through storing carbon in their biomass and soils. However, the lack of global assessments of carbon stocks in seagrass biomass and net primary production (NPP) limits our understanding of their role in the carbon cycle. Here, we provide global estimates of biomass carbon stocks and NPP encompassing seagrasses with different life-history strategies, across bioregions and 66 countries. Seagrass meadows show up to 800-fold differences in biomass across different life-history strategies and bioregions (mean ± SE; 1551 ± 40 kg C ha⁻¹), whereas seagrass NPP (5833 ± 557 …

Live High-Train Low Induced Changes In Hemoglobin Mass And The Erythropoietin-Erythroferrone-Hepcidin Axis In Female Endurance Athletes, Titta Kuorelahti, Johanna K. Ihalainen, Vesa Linnamo, Claire Badenhorst, Oona Kettunen, Ritva Mikkonen

Research outputs 2022 to 2026

The effects of a 21-day live high-train low (LHTL) on hemoglobin mass (Hbmass) and iron demand including the erythropoietin (EPO)-erythroferrone (ERFE)-hepcidin axis and routine iron markers were investigated. Fifteen female endurance athletes completed either 21-day LHTL in normobaric hypoxia (2500 m, ~18 h·day⁻¹) (INT, n = 8) or lived and trained in normoxia (CON, n = 7). Hbmass and resting blood were collected before and after the intervention. An additional blood sample was collected on Day 6 for INT. 21-day LHTL increased Hbmass 3.8% in INT (p < 0.001). EPO increased 35.6% from Day 0 to Day 6 in INT (p = 0.037) and then decreased 42.4% from Day 6 to Day 21 (p = 0.019). In INT, no changes were detected in ERFE or hepcidin, and from the routine iron markers only serum transferrin receptor increased from Day 0 to Day 21 (13.9%, p = 0.013). In CON, no changes were detected in Hbmass or iron markers. In INT, Hbmass and ferritin were positively associated (Day 0 to Day 6, p = 0.005). Thus, hepcidin and ERFE may not provide additional information regarding iron demand following 6- or 21-day LHTL compared to routine iron markers. The relationship between Hbmass and ferritin indicates that adequate ferritin levels are needed during hypoxia to support hematological adaptations.

Perils Of Precisely Equal Group Size In Randomised Controlled Trials, Richard Gray, Daniel Bressington, Bridgina Mackay, Martin Jones, David R. Thompson

Research outputs 2022 to 2026

No abstract provided.

The Influence Of The Marker Set On Inverse Kinematics Results To Inform Markerless Motion Capture Annotations, Marion Mundt, David Pagnon, Steffi Colyer

Research outputs 2022 to 2026

Markerless motion capture has the potential to enable biomechanical analyses without specialised, high-cost equipment. However, the comparability of many markerless motion capture frameworks with the most used marker-based method is limited. One reason for this is the lack of high-quality, biomechanically-informed datasets that are needed to train markerless models. This study aimed to inform the development of such a dataset by systematically analysing the agreement between a gold-standard marker set and a reduced number of markers to solve inverse kinematics (IK). We analysed the impact of different marker positions on the IK solution using an OpenSim lower body model with …

Cnn Based Deep Learning Modeling With Explainability Analysis For Detecting Fraudulent Blockchain Transactions, Mohammad Hasan, Mohammad Shahriar Rahman, Mohammad Jabed Morshed Chowdhury, Iqbal H. Sarker

Research outputs 2022 to 2026

In the era of growing cryptocurrency adoption, Blockchain has emerged as a leading player in the digital payment landscape. However, this widespread popularity also brings forth various security challenges, including the need to safeguard against fraudulent activities. One of the paramount challenges in this regard is the detection of fraudulent transactions within the realm of Bitcoin data. This task significantly influences the trust and security of digital payments. Yet, it's a formidable challenge given the relatively low occurrence of fraudulent Bitcoin transactions. While deep learning techniques have demonstrated their prowess in fraud detection, there remains a scarcity of studies exploring …

Theory And Technology Of Enhanced Coal Seam Gas Production By Integrated Drilling, Punching And Fracturing In Coal Mine: Part 1 Theory, Shiyao Yu, Xianbo Su, Jinxing Song, Qian Wang, Zhenjiang You

Research outputs 2022 to 2026

Coal seams in China are typically characterized by high coal seam gas content and low permeability, posing challenges for efficient coal seam gas extraction. However, achieving successful boreholes, especially in soft coal formations, remains a challenge. The mechanisms underlying permeability improvement in different coal structures need further exploration. Therefore, this paper is focused on the fundamental principles of permeability improvement in soft coal through hydraulic punching, and in hard coal via hydraulic jet fracturing. Firstly, borehole instability results from a dynamic interplay of four factors: in situ stress, coal structure, mechanical properties of coal with fluid, and drilling technology. While …

Feasibility Of A Co-Designed And Personalised Intervention To Improve Vegetable Intake In Rural-Dwelling Young Adults, Katherine Mary Livingstone, Jonathan C. Rawstorn, Stephanie R. Partridge, Yuxin Zhang, Eric O, Stephanie L. Godrich, Sarah A. Mcnaughton, Gilly A. Hendrie, Kathleen M. Dullaghan, Gavin Abbott, Lauren C. Blekkenhorst, Ralph Maddison, Scott Barnett, John C. Mathers, Laura Alston

Research outputs 2022 to 2026

Background: This study determined the feasibility, acceptability, engagement and efficacy of a co-designed and personalised digital intervention to increase vegetable intake (Veg4Me) in young (18-to-35 years) rural-dwelling Australian adults. Methods: Participants living in rural Australia were recruited via local government networks and social media and randomised to receive 12-weeks’ access to personalised (intervention) or non-personalised (control) versions of the free Veg4Me web application. The intervention included: (1) personalised recipes, (2) geo-located food environment map, (3) healthy eating resources, (4) goal-setting portal, and (5) personalised e-newsletters. The primary outcome was feasibility (recruitment, participation, and retention rate). Secondary outcomes were user engagement, …

Impacts Of Dredging And Restoration On Sedimentary Carbon Stocks In Seagrass Meadows Of Pari Island, Indonesia, Yusmiana P. Rahayu, Gary A. Kendrick, Pere Masqué, Wawan Kiswara, Hadiwijaya L. Salim, Ali A. Lubis, Mathew A. Vanderklift

Research outputs 2022 to 2026

The effects of dredging and restoration on carbon sequestration in seagrass sediments is not well understood. Our knowledge is derived from few studies conducted in areas affected by dredging or restoration, the majority of which are from temperate regions. There is limited information available for tropical regions, where seagrass sediments can differ greatly in species composition, geomorphology, and hydrodynamic conditions. This study aims to assess the effects of dredging and seagrass restoration on sediment organic carbon concentrations and stocks at Pari Island, Indonesia. The results indicated that sediment organic carbon concentrations (%Corg) were higher in persistent seagrass meadows than in …

Characteristics Of Australian And New Zealand Osteopaths Who Treat Patients Presenting With Non-Musculoskeletal Complaints: Outcomes From Two Practice-Based Research Networks, Brett Vaughan, Francesco Cerritelli, Jerry Draper-Rodi, Jack Feehan, Ana Paula A. Ferreira, Michael Fleischmann, Gopi Mcleod, Cindy Mcintyre, Chantal Morin, Lee Muddle, Oliver P. Thomson, Loïc Treffel, Nicholas Tripodi, Kesava Kovanur Sampath, Niklas Sinderholm Sposato, Amie Steel, Jon Adams

Research outputs 2022 to 2026

Background: Australian and New Zealand osteopaths predominantly manage musculoskeletal complaints using a variety of modalities including manual therapy, exercise and lifestyle and occupational advice. There appears to be a small percentage of patients who seek osteopathy care for non-musculoskeletal issues such as conditions affecting the gastrointestinal tract. The evidence base for osteopathic treatment as part of the management of such conditions is equivocal. The aim of this study was to describe the practice of Australian and New Zealand osteopaths who report often treating patients with non-musculoskeletal complaints. Methods: This study is a secondary analysis of data from the Australian and …

Comparison Of Respiratory Responses To Exercise Under Different Heat-Stressful Environments Between Oral Contraceptive And Naturally Menstruating Ovulating Female Athletes, Nanako Hayashi, Toby Mündel, Tze Huan Lei, Claire Badenhorst

Research outputs 2022 to 2026

The present study conducted a secondary analysis of previous data (Lei et al., 2017, 2019) to compare exercise-induced respiratory responses under heat stress between the early follicular (EF)/ quasi -EF and mid-luteal (ML)/ quasi -ML phases in naturally menstruating and oral contraceptive pill (OCP)-using female athletes. Additionally, the study aimed to examine the associations between respiratory responses, thermoregulation, and hormonal profiles within each group. Sixteen endurance-trained female athletes participated: eight with a natural menstrual cycle (NM group) and eight using OCP (OCP group). Each participant completed four trials, comprising fixed-intensity cycling (at 125 and 150 W) followed by a 30-min …

A Scoping Review Of Factors Influencing The Implementation Of Liquid Biopsy For Cancer Care, Samran Sheriff, Maree Saba, Romika Patel, Georgia Fisher, Tanja Schroeder, Gaston Arnolda, Dan Luo, Lydia Warburton, Elin Gray, Georgina Long, Jeffrey Braithwaite, Helen Rizos, Louise Ann Ellis

Research outputs 2022 to 2026

Background: Liquid biopsy (LB) offers a promising, minimally invasive alternative to traditional tissue biopsies in cancer care, enabling real-time monitoring and personalized treatment. Despite its potential, the routine implementation of LB in clinical practice faces significant challenges. This scoping review examines the barriers and facilitators influencing the implementation of liquid biopsies into standard cancer care. Methods: Four academic databases (PubMed, Scopus, Embase, and Web of Science) were systematically searched without language restrictions. We included peer-reviewed articles that were published between January 2019 and March 2024 that focused on the implementation of LB in cancer care or described barriers and facilitators …

Determining Timeframes To Death For Imminently Dying Patients: A Retrospective Cohort Study, Tricia O’Connor, Wai Man Liu, Juliane Samara, Joanne Lewis, Karen Strickland, Catherine Paterson

Research outputs 2022 to 2026

Background: Clinicians are frequently asked ‘how long’ questions at end-of-life by patients and those important to them, yet predicting timeframes to death remains uncertain, even in the last weeks and days of life. Patients and families wish to know so they can ask questions, plan, make decisions, have time to visit and say their goodbyes, and have holistic care needs met. Consequently, this necessitates a more accurate assessment of empirical data to better inform prognostication and reduce uncertainty around time until death. The aims of this study were to determine the timeframes for palliative care patients (a) between becoming comatose …

Feasibility Of Home-Based Urine Collection In Children Under 5 Years In The Origins Birth Cohort Study: Mixed Method Protocol And Sample Completion Results, Courtney D.A. Kidd, Najma A. Moumin, Andrea Macrae, Tim J. Green, Desiree T. Silva, Susan L. Prescott, Nina D’Vaz

Research outputs 2022 to 2026

Background: Urine is an attractive biospecimen for nutritional status and population health surveys. It is an excellent non-invasive alternative to blood for appropriate biomarkers in young children and is suitable for home-based collection, enabling representative collections across a population. However, the bulk of literature in this population is restricted to collection in primary care settings. Feasibility of home-based collection at scale has not been tested. Here, we describe a mixed method approach to collect urine samples in a large cohort study with children under 5 years. Methods: The ORIGINS Project is an ongoing birth cohort investigating early life influences on …