Digital Commons Network^™

Corporate Taxation And Industrial Policy, Reuven S. Avi-Yonah

Articles

The Trump administration recently announced two new ventures into industrial policy. First, it will impose a levy on chip exports to China by Nvidia and Advanced Micro Devices (AMD). Under the agreement, Nvidia and AMD will pay the government 15 percent of their gross revenue from sales to China. The secretary of the Treasury has said the administration will consider expanding this type of deal to other industries. Second, the administration announced that it will take a 9.9 percent equity stake in Intel

Tillage Legacy, Grasses And Soil Texture Shape Soil Organic Carbon Recovery In Semi-Arid Woodland, Samantha Colunga, Alejandro Fierro-Cabo, Bradley O. Christoffersen, Engil Pereira

School of Earth, Environmental, & Marine Sciences Faculty Publications

Soil degradation from intensive tillage poses a critical barrier to carbon sequestration, particularly in semi-arid regions where low rainfall limits ecosystem recovery. As climate change expands arid zones globally, understanding the long-term potential for soil organic carbon (SOC) recovery in degraded lands becomes increasingly urgent. Here, we analyze reforested chronosequences (4–36 years post-abandonment) in formerly cultivated subtropical thornscrub woodlands to assess SOC dynamics across gradients of soil texture and degradation. We introduce a novel degradation index (DI), integrating SOC deficit and grass dominance, to evaluate how invasive grasses, commonly overlooked in restoration metrics, impede nitrogen (N2)-fixing tree establishment and, consequently, …

Exploring The Correlation Between Pupil Distance And Myopia Prevalence: An Observational Bioanthropology Study In Surabaya, Anggitha Hayuning Kinasih, Dwi Martha Nur Aditya, Y Adhimas Setyo Wicaksono

Folia Medica Indonesiana

Bioanthropology integrates biological and cultural perspectives, thereby enhancing our understanding of human health across populations. Myopia is a significant refractive error affecting potentially 2.5 billion people globally by the end of the decade. Bioanthropological theories suggest that pupil diameter and distance contribute to axial elongation and the progression of myopia. Nevertheless, current literature lacks empirical validation through rigorous hypothesis testing, highlighting a gap in comprehension. The research explores the relationship between pupil distance and the incidence of myopia via empirical assessments in Surabaya. An observational cross-sectional study was conducted, which involved pupil distance measurements and eye refraction assessments. Inclusion criteria …

Understanding The Role Of Street Medicine In Harm Reduction: A Case Study Of Street Medicine St. Louis, Ari Gzesh, Jeremiah S Truel, Danielle R Adams, Luke Zabotka, Sara Malone, Nathanial S Nolan

2020-Current year OA Pubs

BACKGROUND: Homelessness results from, and exacerbates, various social determinants of health, including poverty, racism, and inadequate healthcare access, which are further compounded by physical and mental health challenges. The street medicine movement seeks to address these disparities by providing direct medical care and harm reduction services to unsheltered homeless in low-barrier settings. The development of trust is critical to providing this form of care. Few studies have sought to understand the factors influencing trust development in street medicine encounters.

METHODS: This case study of Street Medicine St. Louis aims to explore the factors that influence trust and how trust development …

Ohio University Faculty Senate Minutes October 6, 2025, Angela Brock

Faculty Senate Minutes

No abstract provided.

Investigation Of Lncrna Expression In Newly Diagnosed Multiple Myeloma Reveals A Linc01432-Celf2 Axis As An Inhibitor Of Apoptosis, Richa Mishra, Prasanth Thunuguntla, Dhanusha Duraiyan, Alani Perkin, Katelyn Bagwill, Savannah Gonzales, Catheryn Sizemore, Vanessa Brizuela, Jaiyana King, Stephen Daly, Yoon Jae Chang, Mahdote Abebe, Yash Rajana, Kelly Wichmann, Christ Enyan, Shruthi Rangineni, Mark Fiala, Julie Fortier, Reyka Jayasinghe, Mark Schroeder, Li Ding, Ravi Vij, John Dipersio, Jessica Silva-Fisher

2020-Current year OA Pubs

Multiple myeloma (MM) is an incurable malignancy of plasma cells, with over 35,000 new cases diagnosed annually in the United States. Despite an expanding arsenal of approved therapies, nearly all patients relapse, and mechanisms underlying disease progression remain poorly understood. In particular, the role of long non-coding RNAs (lncRNAs) in MM progression and treatment response is largely unexplored. To address this gap, we performed transcriptome sequencing of newly diagnosed MM (NDMM) patient samples and compared individuals with short progression-free survival (PFS; < 24 months) to those with prolonged PFS (>24 months) following standard first-line therapy. We identified 157 lncRNAs upregulated in patients with short PFS, and prioritized the …

Apoe-Calypse Tau: Apoe-Tau Synergy In Alzheimer's Disease, Matthew Paul Lennol, Chiara Bordier, Léana Kamelher, Jason D Ulrich, David M Holtzman, Maud Gratuze

2020-Current year OA Pubs

Alzheimer's disease (AD), the most common cause of dementia, is characterized by the accumulation of amyloid-β (Aβ) in senile plaques and abnormally hyperphosphorylated tau proteins in neurofibrillary tangles. While much of the research has focused on Aβ, tau-mediated neurodegeneration is more closely associated with synaptic loss and cognitive decline in AD, emphasizing the need for a deeper understanding of tau pathology. In this context, the interaction between tau and APOE, particularly the main genetic risk factor for AD APOE ε4, remains underexplored. APOE encodes apolipoprotein E (apoE), a protein important in lipid metabolism. In addition to promoting Aβ deposition, emerging …

Rescue Epilepsy Medication And Training: A Comparison Between Midazolam Use, Guidelines, Clinical Practice, And Possibilities In The Uk And Norway, Rohit Shankar

Peninsula Medical School

Objectives: Status epilepticus (SE) is a prolonged epileptic seizure carrying significant risk of long-term disability and death. Rescue therapies are prescribedfor prehospital administration to terminate SE. This study compared prescribingpractices of rescue therapies of midazolam in the UK and Norway.Methods: A cross-sectional, online, 21-item Likert-style survey was administeredto epilepsy professionals in the UK circulated via ILAE/ESNA and in Norway viaILAE/Epilepsinet using a non-discriminatory exponential snowballing techniqueleading to non-probability sampling. Data were collected anonymously and analyzed using descriptive statistics, Mann–Whitney, Chi-square, and Fisher's exact tests. Significance was accepted at p<0.05.Results: All 86 UK and 53 Norway respondents identified buccal midazolam as the first-line rescue medication choice in the community for prolonged and/or generalized tonic–clonic seizures. Norwegian respondents had significantly more experience in epilepsy-related work (p=0.002), were more likely to have a larger caseload on buccal midazolam (p<0.001), prescribed higher midazolam doses (p<0.001), and provided training yearly (p<0.001). UK respondents were more likely to delegate rescue medication prescribing to primary care (p=0.006) and reviewed emergency management plans more frequently (p=0.006). There was an inter-country difference in the period of midazolam non-use that respondents required before withdrawing from treatment plans (p<0.001). Concern about inappropriate use of buccal midazolam was similarly high in both countries.Significance: This study compared epilepsy professionals in two neighboringhigh-income countries. Findings suggest an urgent need for international guidelines to recommend best practices on prescribing doses and withdrawal of buccal midazolam. The potential abuse of buccal midazolam by patients and carers warrants further investigation.

Practicing With Intent: How To Teach An Old Dogma New Tricks, Matthew C Phillips, Kusha Davar, Sarah Freling, Steven Y C Tong, Todd C Lee, Emily G Mcdonald, Travis B Nielsen, Noah Wald-Dickler, Alfredo J Mena Lora, Rachael A Lee, Fergus Hamilton, Daniel M Musher, Rodrigo P L Costa, Bassam Ghanem, Rachel Baden, Brad Spellberg

Faculty, Staff and Students Publications

Clinicians are constantly bombarded with an onslaught of newly published data, yet they must make clinical decisions despite a dearth of clinical data. Sometimes, they may fall back on clinical practices entrenched by experience, unaware that they are upheld by dogmatic tradition rather than robust evidence. Ideally, the totality of evidence must be assessed and utilized for clinical decision-making, irrespective of entrenched orthodoxy. Here, we explore the questions, how much evidence is needed to revise established clinical practices and, more fundamentally, can data alone truly catalyze such shifts.

Atg Conjugation-Dependent/Independent Mechanisms Underlie Lysosomal Stress-Induced Tfeb Regulation, Shiori Akayama, Takayuki Shima, Tatsuya Kaminishi, Mengying Cui, Jlenia Monfregola, Kohei Nishino, Andrea Ballabio, Hidetaka Kosako, Tamotsu Yoshimori, Shuhei Nakamura

Duncan NRI Faculty and Staff Publications

TFEB, a master regulator of autophagy and lysosomal biogenesis, is activated by several cellular stresses including lysosomal damage, but its underlying mechanism is unclear. TFEB activation during lysosomal damage depends on the ATG conjugation system, which mediates lipidation of ATG8 proteins. Here, we newly identify ATG conjugation-independent TFEB regulation that precedes ATG conjugation-dependent regulation, designated Modes I and II, respectively. We reveal unique regulators of TFEB in each mode: APEX1 in Mode I and CCT7 and/or TRIP6 in Mode II. APEX1 interacts with TFEB independently of the ATG conjugation system, and is required for TFEB stability, while both CCT7 and …

New Avenues In Childhood Vasculitis, Hulya Ercan Emreol, Cagri Yildirim-Toruner, Marija Jelusic, Marinka Twilt, Seza Ozen

Faculty, Staff and Students Publications

Childhood vasculitis encompasses a group of rare and heterogeneous diseases with systemic inflammation affecting various vessel sizes. This comprehensive review highlights recent advances in the pathogenesis, biomarkers, diagnosis, and treatment strategies for major pediatric vasculitides including IgA vasculitis, Kawasaki Disease, ANCA-associated vasculitis, Takayasu arteritis, and Polyarteritis Nodosa. Novel insights from genetic, immunologic, and imaging studies have paved the way for early diagnosis and individualized therapeutic approaches. Future directions emphasize the role of artificial intelligence, precision medicine, and international collaborative trials to optimize long-term outcomes and quality of life in affected children.

Strain-Specific Variability In Viral Kinetics, Cytokine Response, And Cellular Damage In Air-Liquid Cultures Of Human Nasal Organoids After Infection With Sars-Cov-2, Gina M Aloisio, Trevor J Mcbride, Letisha Aideyan, Emily M Schultz, Ashley M Murray, Anubama Rajan, Erin G Nicholson, David Henke, Laura Ferlic-Stark, Amal Kambal, Hannah L Johnson, Elina A Mosa, Fabio Stossi, Sarah E Blutt, Pedro A Piedra, Vasanthi Avadhanula

Faculty, Staff and Students Publications

SARS-CoV-2 variants have demonstrated distinct epidemiological patterns and clinical presentations throughout the COVID-19 pandemic. Understanding variant-specific differences at the respiratory epithelium is crucial for understanding their pathogenesis. Here, we utilized human nasal organoid air-liquid interface (HNO-ALI) cell cultures to compare the viral replication kinetics, innate immune response, and epithelial damage of six different strains of SARS-CoV-2 (B.1.2, WA, Alpha, Beta, Delta, and Omicron). All variants replicated efficiently in HNO-ALIs, but with distinct replication kinetic patterns. The Delta variant exhibited delayed replication kinetics, achieving a steady state at 6 days post-infection compared to 3 days for other variants. Cytokine analysis revealed …

A Supplement, Not A Substitute: Accuracy And Completeness Of Chatgpt Responses For Common Elbow Pathology, Benjamin Fiedler, Umar Ghilzai, Abdullah Ghali, Phillip Goldman, Pablo Coello, Michael B Gottschalk, Eric R Wagner, Adil Shahzad Ahmed

Faculty, Staff and Students Publications

Hypothesis: Large language models (LLMs) like ChatGPT have increasingly been used as online resources for patients with orthopedic conditions. Yet there is a paucity of information assessing the ability of LLMs to accurately and completely answer patient questions. The present study comparatively assessed both ChatGPT 3.5 and GPT-4 responses to frequently asked questions on common elbow pathologies, scoring for accuracy and completeness. It was hypothesized that ChatGPT 3.5 and GPT-4 would demonstrate high levels of accuracy for the specific query asked, but some responses would lack completeness, and GPT-4 would yield more accurate and complete responses than ChatGPT 3.5.

Methods: …

Improved Allele Frequencies In Gnomad Through Local Ancestry Inference, Pragati Kore, Michael W Wilson, Grace Tiao, Katherine Chao, Philip W Darnowsky, Nicholas A Watts, Jessica Honorato Mauer, Samantha M Baxter, Genome Aggregation Database Consortium, Heidi L Rehm, Mark J Daly, Konrad J Karczewski, Elizabeth G Atkinson

Faculty, Staff and Students Publications

The Genome Aggregation Database (gnomAD) is a foundational resource for allele frequency data, widely used in genomic research and clinical interpretation. However, traditional estimates rely on individual-level genetic ancestry groupings that may obscure variation in recently admixed populations. To improve resolution, we applied local ancestry inference (LAI) to over 27 million variants in two admixed groups: Admixed American (n = 7612) and African/African American (n = 20,250), deriving ancestry-specific allele frequencies. We show that 78.5% and 85.1% of variants in these groups, respectively, exhibit at least a twofold difference in ancestry-specific frequencies. Moreover, 81.49% of variants with LAI information would …

Retrospective, Single-Center Assessment Of A Pharmacist-Led Anti-Methicillin-Resistant Staphylococcus Aureus (Mrsa) Therapy Bundle To Enhance Antimicrobial Stewardship, Jeyma Fernandez, Alice Margulis Landayan, Jorge Murillo, Stephen Breazeale, Timothy Gauthier

All Publications

No abstract provided.

Proceedings Of The Tolkien 2019 Conference (2025), Edited By Will Sherwood, Ross Smith

Journal of Tolkien Research

Book review, by Ross Smith, of Proceedings of the Tolkien 2019 Conference (2025), edited by Will Sherwood.

The Taxonomy And Origins Of Folia: A Brief Review, Donald G. Davis, Louise D. Hose, Harvey R. Duchene

International Journal of Speleology

All folia demonstrate a few common elements: folia (singular, folium) are planar or sub-planar speleothems, slanting downward and away from cave walls and ceilings, and genetically associated with fluctuating environmental interfaces. They were first identified and named from examples in western USA hypogenic caves but have since been identified elsewhere in the world. Folia shelves are typically composed of calcite and interweave smoothly along sub-horizontal contours. Calcite accretion, both chemical and mechanical from suspended particles, follows water-surface fluctuations to form protrusions in arrays along walls and ceilings where new accretion tends to follow the water-surface downward during descending phases, gradually …

The Assessment Of Prosodic Writing Skills Among The Students Of The Arabic Language Bachelor Program In The Light Of The Variables Of Gender And Cumulative Average At King Khalid University, Fatimah Shaaban Asiri

University of Bisha Journal for Educational Sciences

The research aimed to identify the level of prosodic writing skills among the students of the Arabic language bachelor program. To achieve the objectives of the research, the descriptive approach was used. The researcher prepared a prosodic writing skills test. The research sample consisted of (187) male and female undergraduate students in the Arabic language major, males and females, at King Khalid University in its various branches. The results resulted in a list of (10) prosodic writing skills. The results showed that the percentage of mastery of students of the Arabic language program at King Khalid University in prosody writing …

A Proposed Training Program For Developing Reciprocal Teaching Skills For Secondary School English Language, Ahmad Atif Alshehri, Ahmed Awad Asiri

University of Bisha Journal for Educational Sciences

This research aims to prepare a proposed training program for devel-oping reciprocal teaching skills for secondary school English language teachers. To achieve this goal, the researcher prepared a list of recip-rocal teaching skills. In the light of this،, a questionnaire was prepared to identify the training needs of English language teachers at second-ary school and their level of the 315 English language teachers in the secondary school which affiliate to the department of education in Asseer Region. The researcher used the descriptive approach in pre-paring the research tool. The results of research resulted in a list of training needs in …

Level Of The Teaching Practices Promoting Collective Mathematical Argumentation In The Intermediate Stage Mathematics Classrooms, Ibrahim Alhussain Khalil

University of Bisha Journal for Educational Sciences

This study aimed to evaluate the teaching practices that promote collective mathematical argumentation in middle school mathematics classrooms. It adopted the descriptive method. The sample consisted of 24 teachers of mathematics in the middle-school stage in the Middle Education Office of the Bisha Education Directorate. Quantitative observation was used as a data collection tool, which consisted of 26 teaching practices divided into four categories. The study reached several results the most notable of which is that the level of teaching practices that promote mathematical argumentation in general amounted to (2.75 - 4.00) at an average level, in the following order: …

A Suggested Conception Of A Training Program Based On Mathematical Prowess Skills For Primary School Mathematics Teachers, Mohammed Barjas Alshahrani

University of Bisha Journal for Educational Sciences

The current research aims to build a proposed training program for the development of mathematical dexterity skills for primary school mathematics teachers, and to achieve the research objectives, a list of indicators was prepared to achieve the appropriate mathematical dexterity skills for the primary stage, which amounted to (15) indicators distributed over the five mathematical dexterity skills, and through the application of the search tool on Primary school teachers, where the sample amounted to 35 teachers, it was found that there is a great need for these needs, and in light of this, the proposed training program was prepared, and …

Teachers' Conceptions Of Mathematics Fluency And Teaching Practices That Support Creativity And Their Relationship To Teaching Efficiency, Metab Zazoo Al-Enezi

University of Bisha Journal for Educational Sciences

The study aimed to identify the correlation between mathematics teachers’ concepts of fluency in mathematics(MTCF) and teaching efficiency, as well as their teaching practices that support creativity(TPSC) and teaching efficiency, and whether gender (male-female) is a moderator variable in this relationship. The study sample consisted of (170) teachers divided into (103) male and (67) female. The results of the study concluded that there is a weak, positive, and significant correlation between teachers’ concepts of fluency in mathematics and their teaching efficiency, as well as a medium, positive, and significant correlation between teaching practices that support creativity and their teaching efficiency, …

A Proposed Program In Earth And Space Based On The Next Generation Science Standards (Ngss) To Develop Some Habits Of Mind For Kindergarten Children, Mona Hashim Alzahrani

University of Bisha Journal for Educational Sciences

The study aimed to prepare a list of (NGSS) standards that must be available in the content of the kindergarten curriculum, with determining the level of inclusion of the three dimensions of the (NGSS) standards in the content of kindergarten curricula, and to develop some habits of reasoning and performance skills among kindergarten students, and the descriptive approach was used. And the experimental approach to achieve the study through application on consisting of 15 children in the kindergarten stage, whose ages range from (4-6) years. The dimensions and sum of the performance skills test and the dimensions and sum of …

Functional Competencies Of Academic Leaders In Saudi Universities In The Light Of The Objectives Of The Human Capacity Development Program (A Proposed Program), Mohammed Ahmed Ali Al Musallat, Muhammad Ahmad Huwaihi

University of Bisha Journal for Educational Sciences

The research aimed to present a proposed program for developing the functional competencies of academic leaders in Saudi universities in light of Human Capacity Development Program objectives. It used the descriptive survey method and a questionnaire consisting of (38) items distributed over (leadership competencies - technical competencies - behavioral competencies), applied to a sample of (444) faculty members (King Khalid, King Abdul-Aziz, King Saud, Imam Abd al-Rahman al-Faisal and Tabuk(.The research concluded that the sample agreed on the importance of the proposed functional competencies, provided a list of functional competencies, no statistically significant differences between the sample members regarding the …

The Role Of Educational Indicators In Evaluating Educational Performance In Al-Qunfudhah Governorate, Awad Musa Al-Ghamdi

University of Bisha Journal for Educational Sciences

The study aimed to identify the extent of knowledge of the role of educational indicators in evaluating educational performance in schools, as well as to identify the reasons and justifications for the role of educational indicators in evaluating educational performance in schools of the two crosses sector. To achieve the objectives of the study, the study relied on the descriptive analytical approach, and the questionnaire as a tool for collecting field data, and the study sample reached (28) individuals, and to analyze the study data, many descriptive statistical methods included in the SPSS statistical package were employed, and the most …

The Degree Of Employing Science Teachers In The Intermediate Level Of Lateral Thinking Skills In Bisha Governorate, Ksa, From The Point Of View Of The Teachers Themselves, Khaled Saleh Alrawili

University of Bisha Journal for Educational Sciences

This research aim to identify the degree of employing science teachers in the intermediate level of lateral thinking skills in Bisha Governorate, KSA, from the point of view of the teachers themselves, and to discover differences in the degree of employing these skills, according to the variables: gender, educational qualification, number of experience years, and number of training courses. To achieve this goals, the descriptive survey approach was followed. By selecting a sample of science teachers in the intermediate stage, which amounted to (140) male and female teachers, and building a questionnaire to employ lateral thinking skills, The application of …

The Effective Of Applying The Service-Learning In Teaching Art Education On Developing Thinking Skills Among High School Students, Ghadah Shukri Albakri

University of Bisha Journal for Educational Sciences

The objective of the research is to measure the effect of applying the service-learning strategy on secondary school students while learning art education on the development of their mental abilities represented in each of the thinking skills. The research followed the semi-experimental approach and was conducted on a sample of 60 high school students. The results showed that there were statistically significant differences between the averages of the control and experimental groups in the post-measurement at the level of reflective and critical thinking skills, where the significance level came with values less than 0.05 on all skills, and the difference …

Innovation In Educational Leadership Research: A Proposed Model For Criteria And Measurement Indicators In Light Of The Vision Of The Kingdom Of Saudi Arabia 2030, Omear Safar Omear Alghamdi

University of Bisha Journal for Educational Sciences

This study aimed to build a proposed model for criteria and indicators of measuring innovation in educational leadership research in light of the Saudi Vision 2030. The reality of innovation in educational leadership research was determined through an electronic questionnaire as part of a pilot study that targeted 28 specialists in leadership, management, and educational planning in Saudi universities. The analysis revealed that 60% of the respondents believe that educational leadership research suffers from repetition and lacks effectiveness in supporting creative ideas. Also, 53% of the respondents think there needs to be more investment in developing innovative strategies and work …

The Factorial Construction Of The Psychological Capital Scale And Its Relationship To Some Variables Among Faculty Members At Al-Baha University, Bandar Hamdan Ahmed Alzahrani

University of Bisha Journal for Educational Sciences

The study aimed to reveal the factors contributing to the construction of the psychological capital variable among faculty members at Al-Baha University. And to identify the differences between the average scores of the study sample on the psychological capital scale, which are attributed to the impact of the variable of sex, the nature of the college, nationality, and academic rank. The study used the psychological capital scale prepared by the researcher, and the results of the study showed the presence of four main factors constituting psychological capital: hope, self-efficacy, flexibility, optimism, and the absence of a statistically significant difference between …

A Proposed Vision For The Role Of Community Partnership In Supporting Scientific Research To Achieve The Vision Of The Kingdom Of Saudi Arabia 2030 (Shaqra University As A Model), Falah Khalaf Alajrafi

University of Bisha Journal for Educational Sciences

The study aimed to provide a proposed vision for the role of community partnership in supporting scientific research at Shaqra University to achieve the vision of the Kingdom of Saudi Arabia 2030. The study relied on the descriptive approach. The study sample represented by faculty members at Shaqra University. The study concluded that the role of community partnership in supporting scientific research at Shaqra University in the light of the vision of the Kingdom of Saudi Arabia 2030 from the point of view of the study sample is achieved to a moderate degree, and the obstacles to the role of …