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Isolating And Quantifying The Role Of Developmental Noise In Generating Phenotypic Variation, Maria Kiskowski, Tilmann Glimm, Nickolas Moreno, Tony Gamble, Ylenia Chiari Apr 2019

Isolating And Quantifying The Role Of Developmental Noise In Generating Phenotypic Variation, Maria Kiskowski, Tilmann Glimm, Nickolas Moreno, Tony Gamble, Ylenia Chiari

Biological Sciences Faculty Research and Publications

Genotypic variation, environmental variation, and their interaction may produce variation in the developmental process and cause phenotypic differences among individuals. Developmental noise, which arises during development from stochasticity in cellular and molecular processes when genotype and environment are fixed, also contributes to phenotypic variation. While evolutionary biology has long focused on teasing apart the relative contribution of genes and environment to phenotypic variation, our understanding of the role of developmental noise has lagged due to technical difficulties in directly measuring the contribution of developmental noise. The influence of developmental noise is likely underestimated in studies of phenotypic variation due to …


Public Relations Practices For Enhanced Services Delivery And Librarians' Image In School Libraries In Abia State, South East Nigeria, Ozioko Reuben Ejike Apr 2019

Public Relations Practices For Enhanced Services Delivery And Librarians' Image In School Libraries In Abia State, South East Nigeria, Ozioko Reuben Ejike

Library Philosophy and Practice (e-journal)

Abstract

This study investigated Public Relations Practices for enhanced Service Delivery and Librarians’ image in School Libraries inAbia State, South East Nigeria. A descriptive survey design was used for the study. The population was 135 teacher librarians in the selected secondary schools in the state. Questionnaire was the instrument used for data collection. Data generated was analysed using descriptive statistics consisting of frequency tables and mean scores. The findings of the study show that the services offered to school library users are lending services to teachers and students, provision of seating and study facilities and user education. Also thedominant public …


Comparative Analysis Of Funding And Finance Of Libraries In Federal University, Polytechnic And College Of Education In Ogun State., Khadijat Dayo Ajayi, Basirat Olubukola Diyaolu, Oyintola Isiaka Amusa Apr 2019

Comparative Analysis Of Funding And Finance Of Libraries In Federal University, Polytechnic And College Of Education In Ogun State., Khadijat Dayo Ajayi, Basirat Olubukola Diyaolu, Oyintola Isiaka Amusa

Library Philosophy and Practice (e-journal)

Academic libraries in higher institutions of learning support the vision and mission of the institutions. Its main objective is to support the teaching learning and research activities of both students and lecturers. To achieve this objective there is a need for adequate funding and finance of the library. This study compared and analysed the funding and finance pattern of libraries in federal university, polytechnic, and college of education in Ogun state. Interview was adopted for the study and the respondents are the bursars and librarians of the respective institutions. Three federal higher educational institutions in the state were used for …


Design Of Theoretical Framework: Global And Local Parameters Requirements For Libraries, Sukumar Mandal Apr 2019

Design Of Theoretical Framework: Global And Local Parameters Requirements For Libraries, Sukumar Mandal

Library Philosophy and Practice (e-journal)

Library is one of the important aspect in modern reading environment. Theoretical framework is an inevitable and indispensable for each and every library in the field of automated and digital library system. In this original research paper all the parameters have selected on the basis of global recommendations and local requirements for libraries in six theoretical sections. Designing the theoretical framework in the following areas such as (i) Theoretical framework of integrated library system cluster (ii) Theoretical framework of community communication and interaction (iii) Theoretical framework of digital media archiving cluster (iv) Theoretical framework of content management system (v) Theoretical …


A Look Into The Tuskegee Study Of Untreated Syphilis In The Negro Male In Macon County, Alabama, Austin Valentine Apr 2019

A Look Into The Tuskegee Study Of Untreated Syphilis In The Negro Male In Macon County, Alabama, Austin Valentine

Student Scholarship & Creative Works

In the 1930’s there was growing concerns over a disease known as syphilis. With 300,000 new cases each year, coupled with the disease’s ability to create blindness, arthritis, heart disease and instances of premature death, the search for a way to stop the epidemic quickly was expanding. With such numbers the United States Department of Health needed answers fast (DiIanni 1993).

At this time, the United States was in an economic crisis left by the Great Depression. As a result, the U.S. Department of Health needed to find cheap test subjects in an effort to combat syphilis and prevent its …


Essays In Financial Economics, William Bazley Apr 2019

Essays In Financial Economics, William Bazley

Open Access Dissertations

This dissertation contains three essays in financial economics. The first essay shows that technology-driven innovations in credit markets have real and social implications. Using data from the largest online, peer-to-peer credit market in the United States, I find that borrowing increases when access to traditional credit is restricted, such as after bank mergers and natural disasters. Consequently, online borrowing moderates the diminished growth in business establishments and the heightened crime growth associated with credit scarcity. A percent increase in online lending offsets about 0.25% (0.22%) of the diminished establishment growth and 0.11% (0.18%) of the rise in crime associated with …


Strength Of Reinforced Concrete Elements Strengthened With Carbon Fiber External Reinforcement, B. Sagatov, N. Rakhmanov Apr 2019

Strength Of Reinforced Concrete Elements Strengthened With Carbon Fiber External Reinforcement, B. Sagatov, N. Rakhmanov

Problems of Architecture and Construction

The article presents the results of experimental studies of the mechanism of force transmission through cracks in reinforced concrete elements strengthened with external reinforcement from carbon-fiber materials. New results to assess the ultimate shear resistance and stiffness of sections of reinforced concrete elements with cracks are described.


Conservation And Usage Issues Of Historical And Architectural Heritage In The Cities Of Uzbekistan, Mukhsin Khidirov, Akmal Rayimkulov Apr 2019

Conservation And Usage Issues Of Historical And Architectural Heritage In The Cities Of Uzbekistan, Mukhsin Khidirov, Akmal Rayimkulov

Problems of Architecture and Construction

This article is devoted to the ongoing theoretical and practical work on the problem of preserving the historical and architectural heritage in the cities in Uzbekistan. The main attention was focused on the issues of conservation and use of historical and architectural heritage in the development of master plans for cities.


Module Preganglionic Deformations And Measure Aging Creep Of Heterogeneous Materials, Kh. Turayev Apr 2019

Module Preganglionic Deformations And Measure Aging Creep Of Heterogeneous Materials, Kh. Turayev

Problems of Architecture and Construction

On the basis of numerous studies it can be asserted that the modulus of elastic deformation of aging heterogeneous materials rises with increasing t age, approaching the limiting value of the modules of deformation for inhomogeneous material of very old age. The analysis of experimental studies based on the study of aging materials in the most important cases of their loading shows that the creep measure under conditions of natural in homogeneity for any t is a continuous bounded nonnegative function of t for t>t.


Jahangir’S Palaces Of Architecture, Laziz Rakhimov Apr 2019

Jahangir’S Palaces Of Architecture, Laziz Rakhimov

Problems of Architecture and Construction

In the article we try to analyze the architectural palaces built by King Jahangir. Moreover, the architecture of shelter palaces during Baburid epoch are described in this article. We give attention to developing new Jehangiri Style. We clarify original survey to all Jehangiri Palaces – Chashmi Nur, Badshahi Mahal, Pushkar, Lahor and Nurgarh.


Compositional Solutions And Architectural Tipology Of Kizbibi Khanqah, Ilkhom Makhmatkulov Apr 2019

Compositional Solutions And Architectural Tipology Of Kizbibi Khanqah, Ilkhom Makhmatkulov

Problems of Architecture and Construction

The article provides information on the origin of the architecture of Khanqah Kizbibi, presents the examples from folk stories about the composition, typology and architectural ornaments of this object. Its functional significance and modern architectural solutions, as well as the basics of effective use of the mausoleum, are given.


Numerical Study Of Nonlinear Oscillations Of A Viscoelastic Plate With Concentrated Masses, R. Abdikarimov, D. Khojayev Apr 2019

Numerical Study Of Nonlinear Oscillations Of A Viscoelastic Plate With Concentrated Masses, R. Abdikarimov, D. Khojayev

Problems of Architecture and Construction

Nonlinear oscillations of a viscoelastic rectangular plate with concentrated masses are investigated under different boundary conditions. The solution of the integro-differential equation is obtained using the Bubnov-Galerkin method in combination with the numerical method. The influence of the viscoelastic properties of the material and concentrated masses on the process of oscillations of a plate is shown.


Energy Saving Issues In The Design Of Modern Social Buildings, U. Ablayeva, N. Normatova Apr 2019

Energy Saving Issues In The Design Of Modern Social Buildings, U. Ablayeva, N. Normatova

Problems of Architecture and Construction

Improving the energy efficiency of buildings in recent decades has become one of the main directions of development of the construction industry. It seems appropriate to focus on improving the heat-shielding properties of external walls and windows, as well as a reasonable limitation of infiltration of outside air. Energy saving is a complex task. The concept of an energy efficient home should include not only insulation of structures, but also specific engineering solutions for the ventilation and heating systems.


Determination Of Imposition In Profiled Steroids Working On Non-Cervical Compressio, T. Kasimov Apr 2019

Determination Of Imposition In Profiled Steroids Working On Non-Cervical Compressio, T. Kasimov

Problems of Architecture and Construction

This article provides the solutions to general and local priorities of profiled rods that work for off-center compression. Rods with an open curved profile are effective in general and local priority compared to hot-rolled bars. In the article the author indicated that when cross-sectioned sheets are bent in various shapes, shear stresses are created at the transverse sections when the nonlinear longitudinal force is applied.


Thermo-Physical Calculation Og Buildings On The Basis Of Energy Saving Requirements And The Second Level Of Thermal Protection, B. Aytmuratov Apr 2019

Thermo-Physical Calculation Og Buildings On The Basis Of Energy Saving Requirements And The Second Level Of Thermal Protection, B. Aytmuratov

Problems of Architecture and Construction

One of the ways to increase the energy efficiency of buildings is to increase the resistance of the outer constructions to heat transfer. Therefore, in this article, the second level of thermal protection for the energy efficiency of buildings was examined according to requirments of NRC 2.01.04-97 * and analyzed for Nukus city.


Water Flow To The Earth Ground Soil Of Automobile Roads From Atmospheric Sediments, A. Kayumov, O. Zafarov, D. Kayumov Apr 2019

Water Flow To The Earth Ground Soil Of Automobile Roads From Atmospheric Sediments, A. Kayumov, O. Zafarov, D. Kayumov

Problems of Architecture and Construction

To predict the density, moisture and heaving of soils that they will have during the operation of roads, it is necessary to determine the flow of water into the soil from precipitation falling on the surface of the carriageway and roadsides in the autumn period of moisture accumulation grounds. Therefore, this article provides a method for determining the flow of water into the soil of the road bed from precipitation.


Development Of Software On Water Use, A. Kenjabayev, A. Sultanov Apr 2019

Development Of Software On Water Use, A. Kenjabayev, A. Sultanov

Problems of Architecture and Construction

The article presents a new theoretical basis for the development of software for optimal decision-making on water use. The advantages of using software for effective water use are described, and a viable option for using the model for water use is depicted. It also demonstrates how the software can be used in files in this area.


Usage Of Strain Gauges In Construction, U. Sirojiddinov Apr 2019

Usage Of Strain Gauges In Construction, U. Sirojiddinov

Problems of Architecture and Construction

This article discusses the use of strain gauges in determining the magnitude of the voltage arising in building structures, as well as their use in the dosing and weighing processes of components of reinforced concrete products. The principles and methods of operation of certain types of strain gauges are described.


Technology To Improve The Durability Of Concrete In The Dry Hot Climate Of Uzbekistan, R. Khamrakulov, Kh. Karakulov, A. Jabbarov Apr 2019

Technology To Improve The Durability Of Concrete In The Dry Hot Climate Of Uzbekistan, R. Khamrakulov, Kh. Karakulov, A. Jabbarov

Problems of Architecture and Construction

The article is devoted to the technology of concrete production in the conditions of dry hot climate of Uzbekistan, the methods and tools of construction technology are used to study this problem. The article analyzes the characteristic features of construction technology, taking into account the influence of various local resources. According to the result of the study, relevant recommendations and proposals were prepared for the decision maker (DM).


Simmetric Vibrations Of Two-Layer Elastic Plates, Z. Khudayberdiyev, Sh. Isroilov, Kh. Akhatov Apr 2019

Simmetric Vibrations Of Two-Layer Elastic Plates, Z. Khudayberdiyev, Sh. Isroilov, Kh. Akhatov

Problems of Architecture and Construction

The article depicts the problem of generating vibration equations of the two-layer elastic plate with the equilibrium equations of the three-layer elastic plate. Due to the layout of the case, a system of two-layer elastic plate vibration equations has been obtained from the three-layer elastic plate vibration equations system. Then, the two-layer plate vibration equation system was removed and the graphs of the migration dashed layers were obtained and the corresponding conclusions were drawn.


Design Of The Rigels Of Frame Buildings Taking Into Account The Step-By-Step Loading, U. Khamrakulov, V. Usmanov Apr 2019

Design Of The Rigels Of Frame Buildings Taking Into Account The Step-By-Step Loading, U. Khamrakulov, V. Usmanov

Problems of Architecture and Construction

The article presents the efficiency of accounting for the two-stage operation of the bolt of frame buildings of prefabricated monolithic reinforced concrete. Examples of calculation are carried out that shown all the effectiveness of accounting for the two-stage operation of structures.


Module Preganglionic Deformations And Measure Aging Creep Of Heterogeneous Materials, Kh. Turayev Apr 2019

Module Preganglionic Deformations And Measure Aging Creep Of Heterogeneous Materials, Kh. Turayev

Problems of Architecture and Construction

On the basis of numerous studies it can be asserted that the modulus of elastic deformation of aging heterogeneous materials rises with increasing t age, approaching the limiting value of the modules of deformation for inhomogeneous material of very old age. The analysis of experimental studies based on the study of aging materials in the most important cases of their loading shows that the creep measure under conditions of natural in homogeneity for any t is a continuous bounded nonnegative function of t for t>t.


Medical School Watercooler Newsletter - April 21, 2019, Lindsey Lyle Apr 2019

Medical School Watercooler Newsletter - April 21, 2019, Lindsey Lyle

Watercooler Newsletter

This is the April 21, 2019 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Three decades of 'amazing opportunities'

New MBA concentration aimed at healthcare professionals

Brennan presents at American Burn Association national meeting

Singh honored by Society of Asian American Scientists in Cancer Research

Terry to discuss kidney stones at May Med School Café


Teaching Quantum Computing With Videos, Daniel A. Sabol, Avery Leider, Lewis Westfall, Jack Glinka Apr 2019

Teaching Quantum Computing With Videos, Daniel A. Sabol, Avery Leider, Lewis Westfall, Jack Glinka

Quantum Computing

Quantum computing will likely change our world as we know it today. In bringing together fields such as quantum mechanics, mathematics, and computer science in their construction and application, quantum computers hold a promise of tremendous increase in processing power when compared to present day technology. For an educator, teaching this topic requires that consideration be given to the fact that quantum computing is not only based on hard-to-teach aspects of physics, math, and computing, but that quantum computing itself is still in the early stages of its development. What is certain is that concepts such as Shor’s and Grover’s …


Michael Buenger’S Great Keynote Address At The Aba Court Adr Conference, John Lande Apr 2019

Michael Buenger’S Great Keynote Address At The Aba Court Adr Conference, John Lande

Faculty Blogs

This post discusses the keynote address at the ABA Court ADR Conference, delivered by Michael Buenger, the executive vice-president and chief operating officer of the National Center for State Courts. His talk, Rethinking the Delivery of Justice in a Self-Service Society, focused on the changes needed to deal with social and technological changes in the present and future. He described the reality that the courts and “alternative” dispute resolution are becoming increasingly integrated, and he argued that we need to plan better so that this combined system can better serve the public.


April 21, 2019: More Religious Violence, Bruce Ledewitz Apr 2019

April 21, 2019: More Religious Violence, Bruce Ledewitz

Hallowed Secularism

Blog post, “More Religious Violence“ discusses politics, theology and the law in relation to religion and public life in the democratic United States of America.


In Memoriam: Dr. Lucy Turnbull, University Of Mississippi. Department Of Classics Apr 2019

In Memoriam: Dr. Lucy Turnbull, University Of Mississippi. Department Of Classics

Classics News Archive

We received the sad news Sunday, April 21, 2019 of the death of our emerita colleague, Dr. Lucy Turnbull.


Ligand Selectivity In The Recognition Of Protoberberine Alkaloids By Hybrid-2 Human Telomeric G-Quadruplex: Binding Free Energy Calculation, Fluorescence Binding, And Nmr Experiments, Nanjie Deng, Junchao Xia, Lauren Wickstrom, Clement Lin, Kaibo Wang, Peng He, Yunting Yin, Danzhou Yang Apr 2019

Ligand Selectivity In The Recognition Of Protoberberine Alkaloids By Hybrid-2 Human Telomeric G-Quadruplex: Binding Free Energy Calculation, Fluorescence Binding, And Nmr Experiments, Nanjie Deng, Junchao Xia, Lauren Wickstrom, Clement Lin, Kaibo Wang, Peng He, Yunting Yin, Danzhou Yang

Publications and Research

The human telomeric G-quadruplex (G4) is an attractive target for developing anticancer drugs. Natural products protoberberine alkaloids are known to bind human telomeric G4 and inhibit telomerase. Among several structurally similar protoberberine alkaloids, epiberberine (EPI) shows the greatest specificity in recognizing the human telomeric G4 over duplex DNA and other G4s. Recently, NMR study revealed that EPI recognizes specifically the hybrid-2 form human telomeric G4 by inducing large rearrangements in the 50-flanking segment and loop regions to form a highly extensive four-layered binding pocket. Using the NMR structure of the EPI-human telomeric G4 complex, here we perform molecular dynamics free …


Pyy3-36 Efficacy Is Independent Of Photoperiod But Dependent On Time Of Day, Marissa Maroni Apr 2019

Pyy3-36 Efficacy Is Independent Of Photoperiod But Dependent On Time Of Day, Marissa Maroni

Honors Program Theses and Projects

Approximately 70% of Americans are overweight or obese and studies have shown that poverty-dense American counties are the most prone to obesity (Levine, 2011). Along with diet, the endogenous circadian rhythms have been found to be an important piece of human metabolic health. Circadian disruption in humans, such as jet-lag and shift work, have been linked to metabolic problems such as Type 2 Diabetes Mellitus and Metabolic Syndrome. Since circadian disruption affects many demographics including shift workers and routine business travelers it is imperative to understand the biological mechanism behind the relationship between circadian disruption and weight gain. One potential …


St. Francis Of Assisi Catholic Church And Center For The Deaf Sunday Bulletin, April 21, 2019 Apr 2019

St. Francis Of Assisi Catholic Church And Center For The Deaf Sunday Bulletin, April 21, 2019

Saint Francis of Assisi Catholic Church and Center for the Deaf Sunday Bulletin

A newsletter published for Deaf Catholics in Landover Hills, MD

St. Francis of Assisi Catholic Church and Center for the Deaf Sunday Bulletin Finding Aid