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Microbiota Signatures In Type-2 Diabetic Patients With Chronic Kidney Disease - A Pilot Study, Gratiela P. Gradisteanu, Roxana A. Stoica, Laura Petcu, Ariana Picu, Adrian P. Suceveanu, Teodor Salmen, Diana S. Stefan, Cristian Serafinceanu, Mariana Carmen Chifiriuc, Anca P. Stoian

Journal of Mind and Medical Sciences

The human microbiota is paramount for normal host physiology. Altered host-microbiome interactions are part of the pathogenesis of numerous common ailments. Currently, much emphasis is placed on the involvement of the microbiome in the pathogenesis of type-2 diabetes mellitus (T2DM), impaired glucose tolerance, and other metabolic disorders (i.e. obesity). Several studies found highly significant correlations of specific intestinal bacteria with T2DM. A better understanding of the role of the microbiome in diabetes and its complications might provide new insights in the development of new therapeutic principles.

Our pilot study investigates the microbiota patterns in Romanian type-2 diabetic patients with diabetic …

Experimental Pharmacological Research Regarding Some New Quinazolin-4-Ones Derivatives, Cornel Chiriță, Emil Ștefănescu, Cristina E. Zbârcea, Simona Negreș, Mihaela Bratu, Diana C. Nuță, Carmen Limban, Ileana C. Chiriță, Cristina D. Marineci

Journal of Mind and Medical Sciences

A series of new compounds with quinazolin-4-one structure, synthesized by the Pharmaceutical Chemistry Department of the Faculty of Pharmacy of the University of Medicine and Pharmacy “Carol Davila” Bucharest, was studied. Five of them were selected, conventionally named S1, S2, S3, S4, S5, and investigated in terms of their potential influence on the central nervous system (CNS). For this purpose, the antidepressant effect was determined using the forced swimming test; the anxiolytic/ anxiogenic effect was determined using the suspended plus-shaped maze (Ugo Basile); the effect on the motor activity was determined using the Ugo Basile activity cage; and the potential …

Brain Image Clustering By Wavelet Energy And Cbsso Optimization Algorithm, Hasan Hosseinzadeh, Mohammad Sedaghat

Journal of Mind and Medical Sciences

Previously, the diagnosis of brain abnormality was significantly important in the saving of social and hospital resources. Wavelet energy is known as an effective feature detection which has great efficiency in different utilities. This paper suggests a new method based on wavelet energy to automatically classify magnetic resonance imaging (MRI) brain images into two groups (normal and abnormal), utilizing support vector machine (SVM) classification based on chaotic binary shark smell optimization (CBSSO) to optimize the SVM weights.

The results of the suggested CBSSO-based KSVM are compared favorably to several other methods in terms of better sensitivity and authenticity. The proposed …

Postpartum Depression And Thyroid Dysfunction– Should Pregnant Women Be Screened For Thyroid Disorders?, Anca A. Simionescu, Erika Marin

Journal of Mind and Medical Sciences

The relationship between thyroid dysfunction and postpartum depression has been investigated for quite some time now, but no consensus has been reached regarding the need for screening for thyroid function during pregnancy. This paper aims to investigate whether thyroid hormone screening in pregnancy might contribute to the diagnosis of postpartum depression.

Depression was assessed using the Edinburgh Postnatal Depression Scale (EPDS) - one of the most widely used measures in detecting postpartum depression and anxiety. Thyroid function was measured using the commonly recommended thyroid laboratory tests.

A structured questionnaire was given to 61 patients closely monitored during their pregnancy and …

Vulnerability And Physical Well-Being Of Caregivers: What Relationship?, Salvatore Settineri, Fabio Frisone, Angela Alibrandi, Emanuele Maria Merlo

Journal of Mind and Medical Sciences

Objectives. To assess relationships among burden, compassion, and well-being and health among an active group of caregivers.

Methods. 301 caregivers with female prevalence (F = 61.1%, M = 38.9%) and ages between 18 and 84 years old (average = 38.72; SD 13.36) participated. Evaluation was carried using standardized instruments to assess: Burdens (CBI), dimensions related to Compassion and Burnout (ProQOL-5), State of Well-being (Who-5) and particular health-related domains (Emotional state, Physical health, Depressive Polarity, Dysphoric Polarity-SF-36). Correlational analyses and multivariate linear regressions were performed.

Results. Positive correlations emerged between Burdens and Compassion Fatigue, Well-being and Satisfaction; inverse correlations emerged among …

Microleakage - The Main Culprit In Bracket Bond Failure?, Ioana Roxana Bordea, Adina Sîrbu, Ondine Lucaciu, Aranka Ilea, Radu Septimiu Câmpian, Doina Adina Todea, Teodora Gabriela Alexescu, Maria Aluaș, Corina Budin, Andreea Simona Pop

Journal of Mind and Medical Sciences

Microleakage is the most common cause of bracket debonding. Moreover, different thermal expansion coefficients between the enamel, the adhesive, and the bracket bases will cause repeated expansion and contraction, adding more stress to the bonding strength. Debonding represents the failure of the adhesion between the brackets and the tooth enamel. The debonding of brackets from the enamel surface is the result of several factors, such as acid-etching and drying, adhesive application, and the time and type of photo activation. The under polymerization process of composite photo activation may lead to early bracket debonding. Objective. The aim of this research …

Serum Markers Of Bone Fragility In Type-2 Diabetes Mellitus, Rucsandra Dănciulescu Miulescu, Loreta Guja, Lavinia Claudia Ochiana, Anca Ungurianu, Oana Cristina Șeremet, Emil Ștefănescu

Journal of Mind and Medical Sciences

Patients with type-2 diabetes mellitus (T2DM) have normal or increased bone mineral density (BMD) but despite that, they are characterized by an increased hip and vertebral fracture risk that involves the alteration of bone quality and not the reduction in bone mass. BMD is utilized for the diagnosis and evaluation of osteoporosis, but BMD itself cannot provide an accurate diagnosis of the individuals at increased risk of fracture and, therefore, studies have focused on identifying other risk factors that are partially or fully independent of BMD.

The fracture risk score tool-FRAX® models provide information about a 10-year probability of osteoporotic …

Sinonasal Inverted Papilloma; Recurrence, Malignant Transformation And Risk Factors, Alexandru Meius, Teodora Ghindea, Catalina Pietrosanu, Irina Ionita, Daniel Timofte, Cornelia Nitipir, Laura Mazilu, Andreea Rusescu, Silviu Pituru, Razvan Hainarosie

Journal of Mind and Medical Sciences

Sinonasal inverted papilloma is a rare benign epithelial tumor. Its three main clinical characteristics are the tendency of recurrence, the destructive ability of nearby structures and malignant transformation. The primary manifestations of this tumor include nasal obstruction, headaches, runny nose, hemorrhage and impaired sense of smell. The diagnosis is based on the clinical and endoscopic examination completed by CT or MRI scans and biopsy of the lesion. Allergies, chronic inflammation, nicotinism and viral infections such as HPV infection are considered possible causes of pathogenesis and potential risk factors for relapse and malignancy. The treatment for this condition is the complete …

Photodynamic Therapy As A New Therapeutic Approach Of Oral Lichen Planus, Sandra Milena Tocut, Madalina Irina Mitran, Cristina Iulia Mitran, Mircea Tampa, Maria Isabela Sarbu, Gabriela Loredana Popa, Simona Roxana Georgescu

Journal of Mind and Medical Sciences

Oral lichen planus (OLP) is a chronic, immunologically mediated disease, defined by periods of exacerbation and quiescence. The disease is associated with a low mortality risk, but in some instances, morbidity can be important, especially in extensive, erosive forms, with a significant impact on the quality of life. OLP is a chronic T-cell mediated inflammatory disease involving the oral cavity, the most common lesions being located on the oral mucosa, tongue and gums. Its etiology remains in part unknown, but several factors proved to be involved in the development of the disease (drugs, dental materials, infectious agents, psychological factors, autoimmunity …

Endothelial Dysfunction In Adolescents And Young Adults With Nonalcoholic Liver Disease, Cristiana G. Moise, Octavian Istrătoaie, Ionuț Donoiu, Edme R. Mustafa, Georgică C. Târtea, Diana R. Tudorașcu, Ion Rogoveanu

Journal of Mind and Medical Sciences

Nonalcoholic liver disease is a global public health problem that increases cardiovascular morbidity and mortality in these patients. This paper discusses endothelial dysfunction among patients (adolescents and young adults) with nonalcoholic liver disease.

On the one hand, evidence suggests that cardiovascular disease is the leading cause of mortality in patients with advanced nonalcoholic liver disease and that nonalcoholic fatty liver is associated with an increased risk of cardiovascular disease independent of the presence of cardiovascular risk factors and metabolic syndrome components.

On the other hand, nonalcoholic liver disease, especially the non-inflammatory form of nonalcoholic steatohepatitis, may not only be a …

Immune And Inflammatory Pathways In Non-Alcoholic Steatohepatitis (Nash). An Update, Sorina Cezara Coste, Ionela Popovici, Andreea Maria Stefan, Iulia Breaban, Adela Sitar Taut, Simina Tarmure Sarlea, Angela Cozma, Dorel Sampelean, Olga Hilda Orasan, Vasile Negrean, Lucia Maria Procopciuc

Journal of Mind and Medical Sciences

Non-alcoholic steatohepatitis (NASH), also known as fatty liver disease (FLD), is a major public health problem. It is considered to be the hepatic manifestation of the metabolic syndrome. Chronic inflammation of the liver is an essential key in the progression from simple hepatic steatosis to steatohepatitis, the evolutionary stage of fatty liver disease. Moreover, the innate immune system plays a crucial role in the progression of hepatic inflammation. For this reason, it is of utmost importance to elucidate the connections between immune mechanisms, Toll-like receptor cytokine signalling, in order to find new effective treatments. Further studies are necessary to test …

Primary Renal Hydatid Cyst – A Review, Lucian Iorga, Radu Anghel, Dragos Marcu, Bogdan Socea, Camelia C. Diaconu, Ovidiu G. Bratu, Liliana F. Andronache, Stana Paunica, Dan Liviu Dorel Mischianu

Journal of Mind and Medical Sciences

The aim of this study was to analyze the clinical presentation, diagnosis and treatment of primary renal hydatidosis. A thorough review of the literature was made using the PubMed database. Cystic echinococcosis is a disease that results from infection with the larval stage of Echinococcus granulosus, a tiny tapeworm found in dogs (definitive host), sheep, cattle, goats, foxes and pigs, amongst others (intermediate hosts).

Humans are accidentally intermediate hosts, who become infected by direct contact with infected dogs, by ingesting contaminated raw or undercooked vegetables or by drinking contaminated water. Renal involvement by hydatid disease is uncommon (less than 3-4%), …

High Intensity Interval Training - As Good As In Athletes As In Subjects With Metabolic Syndrome?, Iulia O. Pfingstgraf, Victoria M. Ruta, Vasile Negrean, Mircea I. Handru, Olga H. Orășan, Teodora G. Alexescu

Journal of Mind and Medical Sciences

HIIT training (high intensity interval training) is one of the most effective means of improving both cardio-respiratory and metabolic functions as well as physical performance of athletes. It includes a series of intensive physical exercises (e.g. running until reaching 90% of the maximum possible pulse), with intermittent rest periods. Active intervals can range between 45 and 240 seconds and alternate with easy exercise periods or even rest periods. This type of training is based on a different principle than regular exercises, where the effort is constantly dosed with an average intensity over a longer period of time. Initially, these exercised …

Oncogenesis- Kaleidoscopic And Multi-Level Reality, Firmilian Calota, Cristian Mesina, Stelian Stefanita Mogoanta, Dragos Calota

Journal of Mind and Medical Sciences

Oncogenesis is an extremely complex phenomenon. The mechanisms by which cancer is induced is only partially known. Consequently, therapeutic targets may be uncertain and results are often unsatisfactory. The purpose of this paper is to develop a trans-level and multiple transdisciplinary perspective describing the kaleidoscopic reality of oncogenesis. This manner of understanding oncogenesis as a complex process characterized by a non-linear dynamic, far from equilibrium and with unpredictable evolution, transcends the classical perspective and requires a paradigm shift. This approach is also facilitated by recent studies that focus on group phenomena, with emerging behaviors in a continuous phase transition. Biological …

The Relationship Between Gut Microbiota And Spontaneous Bacterial Peritonitis In Patients With Liver Cirrhosis - A Literature Review, Roxana-Emanuela Popoiag, Anca Mihaela Pantea Stoian, Adrian P. Suceveanu, Andra I. Suceveanu, Laura Mazilu, Irinel R. Parepa, Laura M. Serban, Mihai Paunica, Catalina Motofei, Carmen Fierbinteanu Braticevici

Journal of Mind and Medical Sciences

Gut microbiota is an essential component in the pathogenesis of liver cirrhosis and its complications. There is a direct relationship between the gut and the liver called the gutliver axis through which bacteria can reach the liver through the portal venous blood. However, it remains unclear how bacteria leave the intestine and reach the fluid collection in the abdomen. A series of mechanisms have been postulated to be involved in the pathogenesis of spontaneous bacterial peritonitis (SBP) and other complications of liver cirrhosis, including bacterial translocation, bacterial overgrowth, altered intestinal permeability and dysfunctional immunity. The hepatic function may also be …

Management Options In The Sudden Hearing Loss Of A Diabetic Patient, Andreea Rusescu, Viorel Zainea, Oana Ruxandra Iana, Irina Ioniță, George Traian Alexandru Burcea-Dragomiroiu, Dragos Cristian Ștefănescu, Dumitru Cristinel Badiu, Florentina Gherghiceanu, Catalina Pietrosanu, Corina Silvia Pop, Razvan Hainarosie, Mura Hainarosie

Journal of Mind and Medical Sciences

The aim of our paper is to highlight the main therapeutic principles and the management options in the case of a diabetic patient who has had a sudden hearing loss. Mainly, the aim is to underline the sudden hearing loss treatment adjustment of the diabetic patient compared to the non-diabetic patient.

By understanding the mechanism of sudden hearing loss in a diabetic patient, namely the impact of glycemic variations and their implication on the microvascular structures of the inner ear, we try to underline the treatment principles and management options of the previously mentioned combined pathologies.

Thus, it is necessary …

Physical Exercise – The Friend Or The Enemy Of The Patient With Pulmonary Tuberculosis?, Victoria Maria Ruta, Teodora Gabriela Alexescu, Simina Tarmure, Vasile Negrean, Monica Carmen Pop, Nicoleta Motoc, Iulia Olimpia Pfingstgraf, Mirela Georgiana Perne, Lorena Ciumarnean, Simona Valeria Clichici, Adina Milena Man

Journal of Mind and Medical Sciences

Introduction. Tuberculosis, a major cause of morbidity and mortality, is the second cause of death from an infectious disease, after HIV/AIDS. Each second, a new infection occurs around the globe. Pulmonary tuberculosis can equally affect a performance athlete as well as an aspiring athlete. Physical exercise must be individualized and customized. Pulmonary rehabilitation guides 3 recommend types of exercises for patients with obstructive pathology: stretching, cardiovascular exercise or aerobics. Exercises must be started under medical supervision and must be interrupted if: the ventricular altitude increases above the maximum estimated level for the age, oxygen saturation (SaO2). Aim. The current review …

The Risk Of Bleeding And Encephalopathy In Surgical Patients With Liver Cirrhosis, Petrișor Banu, Salvatore Settineri, Emanuele Maria Merlo, Maria Rosaria Anna Muscatello, Nicolae Bacalbașa, Carolina Negrei, Bianca Gălățeanu, Octav Ghinghină, Ioana Păunica, Cristian Bălălău

Journal of Mind and Medical Sciences

Liver cirrhosis is a disease with an increasing incidence. Surgical procedures in patients with cirrhosis are also increasing, due to a longer life expectancy in these patients and also to the improvement of therapeutic and diagnostic resources.

Digestive hemorrhage in the cirrhotic patient requires emergency medical intervention (intensive therapy, endoscopic or even surgical approaches), being at the same time a factor that precipitates episodes of encephalopathy, i.e. the conventional complication of cirrhosis. Hepatic encephalopathy represents one of the most severe clinical events of cirrhosis, being associated with high morbidity and mortality. The causes of hepatic encephalopathy are briefly presented in …

Ethical Aspects In Managing Patients Diagnosed With Digestive Cancers; A Review Of Literature, Andrada Dumitru, Cornelia Nitipir, Gabriel Preda, Dragos Radu Marcu, Dumitru Cristinel Badiu, Gheorghe Andreea, Corina Silvia Pop, Laura Marina Serban, Roxana Hulea, Silviu Pituru

Journal of Mind and Medical Sciences

Numerous bioethical recommendations are now available in the complex process of communication with cancer patients. In this review, we have focused on the complex process of managing patients with different types of oncologic digestive diseases, immediately after the diagnosis is made.

We have analyzed the literature data on the topic. MEDSCAPE and PubMed databases have been studied. Issues such as telling the truth to patients with digestive cancer, the physician's responsibility in the psychological management of patients and their relatives, the nurses’ duties, the consented death, the practice of euthanasia and physician-assisted suicide (PAS) as well as the clinical research …

Table Of Contents 2019; 6(1); 1-180, . .

Journal of Mind and Medical Sciences

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Demographic Trends Of Walkable Cities In The United States, Christine Leonhardt

Sigma Xi Student Research Symposium (2019)

Walkable cities have become attractive places to live in recent years as they benefit resident’s well-being. Walkable cities have a positive correlation with a population that is young, educated, safe, and healthy. In cities with high-walkability, residents are encouraged to walk more, rather than use a car for each outing, which counters obesity and a sedentary lifestyle, a grim atmosphere, and unsafe surroundings. Most research on walkability and demographics is limited to case studies comparing city neighborhoods, whereas this research encompasses 108 United States cities with a population over 200,000 people. This research goes beyond a city’s walk score, established …

Accessing Bioenergy Potential Based On Loblolly Pine Residues Using Based-Gis Models In Virginia, Gia Nguyen, Erik Lyttek, Meghann Smith, Taylor Wieczerak

Sigma Xi Student Research Symposium (2019)

There is a lack of an assured supply of biomass feedstock for the bioenergy industry, which is often considered a prerequisite for more significant investments in biomass conversion capacity in the US. Cellulosic feedstocks offer the potential to reduce the diversion of food grains (e.g., corn) for energy production, thereby eliminating the food vs. fuel debate. Loblolly pine (Pinus taeda L.) is a perennial evergreen tree found throughout the southern United States and is essential for commercial timber. It proliferates readily, has low maintenance needs, long life expectancy, and is a dependable source of woody biomass. The study aims …

The Arylabialis Muscle Of The Túngara Frog (Engystomops Pustulosus), Amy D. Lagorio, Marcos Gridi-Papp

Pacific Research & Scholarship Day

No abstract provided.

Strategic Analysis Of New Jersey's Lsrp Program By Applying A Combined Swot-Ahp Technique, Robert Oleksy

Sigma Xi Student Research Symposium (2019)

In 2009 the Site Remediation Reform Act (SRRA) was established which created the Licensed Site Remediation Professions (LSRP) program. LSRPs can provide remediation services without delayed approval from the New Jersey Department of Environmental Protection (NJDEP). The result allows for prompt development of contaminated sites. Ten years after its passage, SRRA 2.0 will soon be introduced. To assist in its strategic development, a modified Strength, Weakness, Opportunities and Threats - Analytical Hierarch Process (SWOT-AHP) will be applied to four stockholder groups to determine each groups' preferences of the current LSRP program. The four groups include government/legal entities, business/trade organizations, non-government …

Road Deicing Salts On Groundwater In The Upper Passaic River Basin, New Jersey, Connor Firor, Peter Soriano, Faith Justice, Felix Oteng, Duke Ophori

Sigma Xi Student Research Symposium (2019)

It is known that the use of road deicers is beneficial, but road salts have also been shown to affect surface water and groundwater quality. This study conducted major ion concentration analyses on groundwater samples collected by the United States Geological Survey (USGS) for the Upper Passaic River Basin (UPRB). Results show that the contribution of chloride to total dissolved solids increased significantly by 2010. Trend plots show strong correlation of increases in sodium and chloride with time that are not observed with other major ions such as calcium and magnesium. Decadal bivariate plots of sodium versus chloride show strong …

Life Cycle Assessment Of Pelletized Loblolly Pine (Pinus Taeda) Residues For Coal Co-Firing In Virginia, Michael Fowler

Sigma Xi Student Research Symposium (2019)

The goal of this study is to develop a real-world scenario life cycle with efficient, realistic, geologistics and minimum input demands. Woody biomass is projected to become a growing percentage of domestic electricity generation as a renewable fuel source. However, concerns persist regarding energy content, waste, emissions, ability to provide adequate biomass supply, and policies. Loblolly pine (Pinus taeda) is a short rotation woody crop grown in a substantial portion of the Southeastern United States for lumber and paper pulpwood. Once harvested, the fast-growing softwood can be delimbed and debarked leaving 20% of the biomass as underutilized residues. …

Human Wildlife Conflict And Likelihood To Report The Loss: A Case Study Of Nepal, Gita Bhushal Adhikary, Pankaj Lal, Bernabas Wolde

Sigma Xi Student Research Symposium (2019)

Globally, populations living in proximity to conservation areas have experienced some level of wildlife conflict, ranging from crop loss to severe human injury. Various compensation schemes already exist in developed nations where victims report the conflict and receive compensation for the loss sustained. However, in developing countries, victims face more challenges pertaining to reporting losses to authorities. We used the Banke National Park in Nepal, where literature addressing human-wildlife conflict issues is lacking, as a case study to explore possible factors influencing the propensity to report losses. We surveyed 197 participants; 100% reported suffering from crop raids by wild animals, …

Relationships Between Rejected And Accepted Romantic Initiation Behaviors On Social Media: Self-Esteem And Depressive Feelings In Face-To-Face Interactions, Katie Walker

Pepperdine Journal of Communication Research

Snap, write, upload; smile, tag, post. These are the sequence of actions that have become prevalent amongst social media users. Now, more than ever, such platforms have enabled users to connect with each other, share information, and even initiate romantic relationships. Most social media are designed to stimulate positive interactions among users, for example via “likes” and “favorites,” (Valkenburg, Koutamanis, & Vossen, 2017). However, with this sense of empowerment through a screen also comes the possibility of becoming negatively affected by the interpersonal responses that one receives on social media. Romantic Initiation Behaviors (RIBs) occur anytime one reaches out to …

Call To Action: Climate Change Is Calling, Elizabeth Maccoy, Timothy Good, Sarah Fischbach Phd

Pepperdine Journal of Communication Research

The sustainability movement found in

many popular companies (i.e. Patagonia, Toms Shoes, Rareform) promotes helping the changing climate as part of their marketing strategy. Our research begins to uncover the benefits of these movements that shape student’s thinking towards sustainability. This study aims to evaluate sustainability on the campus of Pepperdine University from the students’ point-of-view after participating in a sustainability project in marketing classes. A convenience non-probability sample of 75 participants engaged in the quantitative Qualtrics online survey. Our results reveal that Pepperdine students who participated in the marketing campaign consider sustainability important, have positive attitudes toward the environment …

Undemocratic And Liable, Noel Kildiszew

Pepperdine Journal of Communication Research

The tragedy of World War II left the world in rubble. In 1945, a continent once controlled by fascist and communist dictators found itself in the process of rehabilitation not only of cities but also of government systems. With Hitler and Mussolini literally out of the equation, the world could seemingly recover peacefully. However, seventy-four years later in 2019, similar problems are beginning to rise out of the ashes of WWII. Under the presidency of Donald Trump, the United States government is beginning to align itself with fascist ideology. Traditionally, fascism creates social and government systems that support a centralized …