Digital Commons Network^™

Role Of Atm In T Cell Dysfunction During Chronic Viral Infections, Juan Zhao

Electronic Theses and Dissertations

Hepatitis C virus (HCV) or human immunodeficiency virus (HIV) infection leads to a phenomenon of inflammaging, in which chronic infection or inflammation induces an immune aged phenotype with T cell dysfunction. Thus, HCV or HIV infection has been deemed as a model to study the mechanisms of T cell infammaging and viral persistence in humans. In this dissertation, T cell homeostasis, DNA damage and repair machineries were investigated in patients with chronic HCV or HIV infection at risk for inflammaging. We found a significant depletion in CD4 T cells, which was correlated with their apoptosis in chronically HCV/HIVinfected patients, compared …

Effect Of Prebiotic, Probiotic, And Enzyme Supplementation On Gut Fermentation, Markers Of Inflammation And Immune Response In Individuals With Gi Symptoms, Kaitlyn Webb

Electronic Theses and Dissertations

Current practices support the use of probiotic and prebiotic supplementation to improve chronic gastrointestinal distress (GID). The aim of this study was to determine the tolerance and benefits of GlutenShield (GS), a prebiotic, probiotic, and enzyme supplement, on adults with GID. Subjects (n=20) took either GS or the placebo for 30 days and completed a pre-treatment FFQ as well as a pre- and post-treatment GID questionnaire, blood draw, and stool sample. Participants consumed more total and saturated fat, and less fiber and whole grains compared to the recommended intake. A significant reduction in IgG2 was observed in the GS group …

Mentoring: Attitudes And Perceptions Of New Lawyers, Mindy Thomas Fulks

Electronic Theses and Dissertations

Tennessee does not have a formal state-wide required mentoring program for Tennessee lawyers. Mentoring programs are available to Tennessee lawyers but no uniform standards exist. It has been suggested that providers of mentoring programs should develop strategies for improving and expanding mentoring experiences for new lawyers. The purpose of this study was to evaluate attitudes towards mentoring by Tennessee lawyers who are within their first 5 years of practice. The researcher sought to identify the perceptions of new lawyers regarding mentoring to better understand mentoring’s role within the legal profession.

The methodology for this study was nonexperimental quantitative survey research. …

Synthesis And Evaluation Of 1,2,4-Oxadiazolidinones: The Search For A Potential Non-Β-Lactam Β-Lactamase Inhibitors., Chimdi Eke Kalu

Electronic Theses and Dissertations

β-lactam antibiotics have been the most widely used drug of choice to combat infectious disease caused by bacteria. Unfortunately, their effectiveness is drastically threatened by bacterial β-lactamases. β-lactamases is responsible for the resistance to most antibiotic drugs. For decades, β-lactam β-lactamases inhibitors have been used to reduce bacterial resistance; however, in this study 1,2,4-oxadiazolidinone derivatives as a non-β-lactam β-lactamases inhibitor against TEM-1 and P99 β-lactamases. The significance of oxadiazolidinone is the prominent five-membered ring scaffold in its structure, which is configurationally stable and present in other biologically active compounds such as linezolid and avibactam. Oxadiazolidinones were synthesized by treating nitrones …

The Eco-Smart Can V2.0, Darack B. Nanto

Electronic Theses and Dissertations

On a scorching summer day in 2015, a campus maintenance worker was observed emptying a trash bin. Upon closer observation, it was noted that the bin was not full; in fact, it was less than one third full. There were other bins that were full and needed to be emptied urgently. It was confusing and problematic to see that bins that needed more attention were not prioritized. After extended research, it was found that maintenance operates on daily routes to pick up trash at designated times, regardless of the level of trash in the bins. Therefore, to tackle this issue, …

Taking Notes: Generating Twelve-Tone Music With Mathematics, Nathan Molder

Electronic Theses and Dissertations

There has often been a connection between music and mathematics. The world of musical composition is full of combinations of orderings of different musical notes, each of which has different sound quality, length, and em phasis. One of the more intricate composition styles is twelve-tone music, where twelve unique notes (up to octave isomorphism) must be used before they can be repeated. In this thesis, we aim to show multiple ways in which mathematics can be used directly to compose twelve-tone musical scores.

Metamorphoses Of 1968: Latin America And The Israel-Palestine Question In Tomás Abraham’S La Dificultad (2015), Stephanie Pridgeon

All Faculty Scholarship

Throughout Tomás Abraham’s novel of ideas La dificultad, Judaism is revealed to be central to the protagonist’s understandings of revolutionary politics, philosophy, and his own identity. As is apparent in his affinity with Palestinian causes as a form of anti-imperialist solidarity, life experiences and politics are inseparable. That Abraham should have chosen to focus this autobiographical novel on the Hungarian-Argentine Jewish narrator’s experiences with the Paris student movements of 1968 suggests that revolutionary movements and the challenges to the global Jewish community continue to affect his identity as a Jew, an Argentine, and a philosopher. A lo largo de la …

Postglacial Relative Sea Level Change And Glacier Activity In The Early And Late Holocene: Wahlenbergfjorden, Nordaustlandet, Svalbard, Anders Schomacker, Wesley R. Farnsworth, Ólafur Ingólfsson, Lis Allaart, Lena Håkansson, Michael Retelle, Marie-Louise Siggaard-Andersen, Niels Jákup Korsgaard, Alexandra Rouillard, Sofia E. Kjellman

All Faculty Scholarship

Sediment cores from Kløverbladvatna, a threshold lake in Wahlenbergfjorden, Nordaustlandet, Svalbard were used to reconstruct Holocene glacier fluctuations. Meltwater from Etonbreen spills over a threshold to the lake, only when the glacier is significantly larger than at present. Lithological logging, loss-on-ignition, ITRAX scanning and radiocarbon dating of the cores show that Kløverbladvatna became isolated from Wahlenbergfjorden c. 5.4 cal. kyr BP due to glacioisostatic rebound. During the Late Holocene, laminated clayey gyttja from lacustrine organic production and surface runoff from the catchment accumulated in the lake. The lacustrine sedimentary record suggests that meltwater only spilled over the threshold at the …

Concealed Campus Carry: Perspectives From Administrators, Faculty And Firearms Instructors On Generating Campus Policy, Diana Villarreal Barfield

Electronic Theses and Dissertations

School shootings have become prominent throughout the Unites States. This is an issue not only in primary schools but also in postsecondary educational institutions. The states of Utah and Colorado passed laws allowing students to carry guns on publicly funded college and university campuses. In 2015, the Texas legislature also proposed a similar campus carry law, which was not passed in 2015. In 2016, when the Texas 84th Legislature made a second attempt, the law was passed. With the passage of this law by the Texas state legislature, a 21-year-old was now allowed to carry a concealed handgun on campus. …

The Relations Of Religiosity, Social Support, And Acculturation Attitudes Among Refugees, Carolyn H. Casada

Electronic Theses and Dissertations

Refugees are entering the United States in increasing numbers. Identifying factors that promote successful acculturation is an important task for those working to help refugees. As religiosity and social support have previously been linked to better mental health outcomes in refugees, they should be considered when examining acculturation. Using the Duke University Religious Index, the Multidimensional Scale of Perceived Social Support, and the Acculturation Attitudes Scale, this study examined the relations between religiosity, perceived social support, and acculturation strategies. Additional variables examined were number of migrations, language of religious services currently attended, and religious services demographics. Hypotheses were that scores …

An Examination Of Multiple Risk Factors Contributing To Student Dropout Risks Using An Ecological Systems Perspective, Karla Denise Carrasco

Electronic Theses and Dissertations

Students who do not complete high school are at risk of higher unemployment, lower wages, and higher incarceration rates. Not only do these impact the individual, but their families and society as well. There are several academic and non-academic factors that can potentially put a student at risk of dropping out of high school. Currently, eligibility criteria for identifying at- risk students, which are used by many Communities in Schools (CIS) Affiliates in Texas that provide a dropout prevention program, are mostly academically based indicators. Incorporating an ecological systems perspective, this study aimed to explore the impact of academic and …

Housing Equity And Household Consumption In Retirement: Evidence From The Singapore Life Panel, Lipeng Chen, Liang Jiang, Sock Yong Phang, Jun Yu

Research Collection School Of Economics

We utilize data from the Singapore Life Panel© survey to empirically investigate the impact of housing equity on consumption of elderly households. Based on panel analysis, we find housing equity value has no significant impact on non-durable consumption for elderly people. The conclusion holds for a battery of robustness check. Moreover, heterogeneity analyses based on subsamples by age of household head, house type, and number of property possessed also show no significant impact of housing equity on consumption in general. Finally, we use scenario analysis to study the Lease Buyback Scheme (LBS), a novel housing equity monetization scheme which allows …

An Improved Bayesian Unit Root Test In Stochastic Volatility Models, Yong Li, Jun Yu

Research Collection School Of Economics

A new posterior odds analysis is developed to test for a unit root in volatilitydynamics in the context of stochastic volatility models. Our analysis extendsthe Bayesian unit root test of So and Li (1999) in two important ways. First,a mixed informative prior distribution with a random weight is introducedfor the Bayesian unit root testing in volatility. Second, a numerically morestable algorithm is introduced to compute Bayes factor, taking into accountthe special structure of the competing models. It can be shown that theapproach introduced overcomes the problem of the diverging “size” in themarginal likelihood approach by So and Li (1999) and …

Wage-Vacancy Contracts And Multiplicity Of Equilibria In A Directed Search Model Of The Labor Market, Nicolas L. Jacquet, John Kennes, Serene Tan

Research Collection School Of Economics

This paper studies a directed search model of the labour market, which is standard in all aspects except two. First, we allow firms to post wage–vacancy contracts advertising the number of workers they would pay as well as the payment all will receive. Second, we consider two cases: one where workers are risk neutral and one where workers are risk averse, both in finite and large economies. Our paper shows that when firms post wage–vacancy contracts, whether workers are modelled as risk neutral or risk averse matters: the types of symmetric equilibria and the nature of multiplicity of equilibria are …

Property In Digital Coins, J.G. Allen

Research Collection Yong Pung How School Of Law

Digital coins have burst into mainstream awareness recently, mainly as a result of high-worth ‘Initial Coin Offerings’ (‘ICOs’). The most immediate question in the legal treatment of digital coins is whether they are properly seen as digital ‘commodities’, and/or as ‘securities’, and/or as units of ‘money’. But the conceptual underpinnings of these categories are not clear, nor is it clear how these categories relate to each other; no legal system currently deals adequately with incorporeal objects as objects of property law. This category includes not only digital coins but also some forms of conventional money and securities. Establishing a satisfactory …

Returning To The Fair Use Standard, Alexander Mcmullan

NYLS Law Review

No abstract provided.

A Survey Of Prediction And Classification Techniques In Multicore Processor Systems, Cristinel Ababei, Milad Ghorbani Moghaddam

Electrical and Computer Engineering Faculty Research and Publications

In multicore processor systems, being able to accurately predict the future provides new optimization opportunities, which otherwise could not be exploited. For example, an oracle able to predict a certain application's behavior running on a smart phone could direct the power manager to switch to appropriate dynamic voltage and frequency scaling modes that would guarantee minimum levels of desired performance while saving energy consumption and thereby prolonging battery life. Using predictions enables systems to become proactive rather than continue to operate in a reactive manner. This prediction-based proactive approach has become increasingly popular in the design and optimization of integrated …

Spectrum, May 1, Special Edition, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: Commencement 2019 -- Senior spring semester -- Campus expansion -- A year in review of SHU sports -- How being a student athlete can prepare you for the real world

Bulletin Ninth District Ny May 2019

Bulletin of the Ninth District Dental Association

The Bulletin of the Ninth District Dental Association is published four times annually in the months of March, May, September and November. It is distributed to all Association members from the counties of Dutchess, Orange, Putnam, Rockland and Westchester in the state of New York.

The Bulletin keeps our members up-to-date on NDDA activities as well as on a variety of topics important to the profession.

Masthead, Cleveland State Law Review

Cleveland State Law Review

No abstract provided.

Catholic Social Teaching And Neo-Abolitionism: Tearing Down The House Of The Rising Sun, Elizabeth M. Donovan

Cleveland State Law Review

Catholic Social Teaching (“CST”) is the body of literature written in the modern era by papal and episcopal teachers in response to current political, economic, and social issues. CST views individuals in the sex trade as victims, however they arrived in the trade. Prostitution abolitionists, called neo-abolitionists, because their current efforts to wipe out sex trafficking and prostitution mirror similar efforts by reformers in the early twentieth century, also view individuals in the sex trade as victims. A coalition of feminists and Christians developed neo-abolitionist social policy during the late twentieth and early twenty-first century. CST and neo-abolitionist social policy …

Clear As Mud: Constitutional Concerns With Clear Affirmative Consent, C. Ashley Saferight

Cleveland State Law Review

Rape and sexual assault laws and policies have shifted significantly in recent years, including the introduction of affirmative consent. Unfortunately, both proponents and critics tend to confuse the issues and falsely equate affirmative consent as a substantive social standard versus a procedural standard for adjudication and punishment. Although affirmative consent generally does not represent a significant change in consent law in the United States, statutes and policies requiring a further requirement that affirmative consent be clear and unambiguous (“clear affirmative consent”) are problematic and raise constitutional concerns. When clear affirmative consent policies are used as an adjudicative standard, they increase …

Ohio's Targeted Community Alternative To Prison Program: How A Good Idea Is Implemented Through Bad Policy, Samantha Sohl

Cleveland State Law Review

Just because a legislature can make a law doesn’t mean that they should. The Ohio General Assembly enacted the Targeted Community Alternatives to Prison (T-CAP) program to decrease the number of convicted defendants sent to state prison and to increase funding for community control efforts. While the law may be upheld under the Ohio Constitution’s Uniformity Clause, the law should still be repealed because legislative control and financial influence have no place in the judicial branch, specifically the criminal sentencing process. However, the law is rooted in good intentions, and many judges have found the additional funding useful, but the …

Investing In A Qualified Opportunity Fund: A Viable Alternative To A Section 1031 Drop-Swap Cash-Out, Bradley T. Borden

Faculty Scholarship

No abstract provided.

A Framework To Guide Undergraduate Education In Interdisciplinary Science, Brie Tripp, Erin E. Shortlidge

Biology Faculty Publications and Presentations

An expanded investment in interdisciplinary research has prompted greater demands to integrate knowledge across disciplinary boundaries. Vision and Change similarly made interdisciplinary expectations a key competency for undergraduate biology majors; however, we are not yet synchronized on the meaning of interdisciplinarity, making this benchmark difficult to meet and assess. Here, we discuss aspects of interdisciplinarity through a historical lens and address various institutional barriers to interdisciplinary work. In an effort to forge a unified path forward, we provide a working definition of interdisciplinary science derived from both the perspectives of science faculty members and scientific organizations. We leveraged the existing …

Marinitoga Lauensis Sp. Nov., A Novel Deep-Sea Hydrothermal Vent Thermophilic Anaerobic Heterotroph With A Prophage, Stéphane L'Haridon, Léna Gouhie, Emily St. John, Anna-Louise Reysenbach

Biology Faculty Publications and Presentations

A novel moderately thermophilic, heterotrophic anaerobe, designated strain LG1T, was isolated from the Mariner deep-sea hydrothermal vent field along the Eastern Lau Spreading Center and Valu Fa Ridge. Cells of strain LG1T were motile rods, occurring singly or in pairs, 0.6μm in width and 1.2μm in length. The strain LG1T grew between 40 and 70°C (optimum 50-55°C), at a pH between 5 and 8 (optimum pH 6.5) and with 7.5-50gL-1 NaCl (optimum 30gL-1). Sulfur, cystine and thiosulfate were reduced to sulfide, and cell yield was improved in the presence of cystine. Strain LG1T was an organotroph able to use a …

Differences Between Male And Female Elite Free-Style Wrestlers In The Effects Of “Set Up” On Leg Attack, Sho Ito, Larry Crawshaw, Kazuyuki Kanosue

Biology Faculty Publications and Presentations

Leg attack is the most basic skill in free-style wrestling. Before executing a leg attack, balance and anticipation of the opponent must be disrupted. We defined this action as the “set up”. The aim of this study is knowledge about the effects of “set up” on the success rate of leg attacks, and answer to question: whether or not a gender difference exists in the use and effectiveness of “set ups” in the elite level of the wrestling matches. Material and Methods: We analyzed video recordings of 57 matches of male free-style wrestling seniors, 58 matches of female seniors, 60 …

The Rise Of The Part-Time Worship Leader In The Mid-Size Southern Baptist Church, Donald Oren Blakeney

Doctoral Dissertations and Projects

The purpose of this paper is to explore the prevalence of part-time, bivocational, semi-retired and volunteer worship leaders within mid-size Southern Baptist church and the need for further training and education through a denominationally-driven mentor program. The known decline in attendance and financial giving that most Southern Baptist churches have experienced has affected the moneys available to fill staffing needs and thereby require a reassessment of staff positions; the percentage of the budget allocated for staffing and continuing education. Most of these part-time worship leaders are already educated in another field and cannot allot the resources for a return to …

Predicting Student Success Using Digital Textbook Analytics In Online Courses, Dustin Lee Williams

Doctoral Dissertations and Projects

In the digital era, students are generating and institutions are collecting more data than ever before. With the constant change in technology, new data points are being created. Digital textbooks are becoming more popular, and textbook publishers are shifting more of their efforts to creating digital content. This shift creates new data points that have the potential to show how students are engaging with course material. The purpose of this correlational study is to determine if digital textbook usage data, pages read, number of days, reading sessions, highlights, bookmarks, notes, searches, downloads and prints can predict student success. This study …

Attitudes And Perceptions Of Concealed Carry On Campus: A Case Study Of Students, Staff, And Faculty At Liberty University, Jeremiah Todd Koester

Doctoral Dissertations and Projects

The number of mass shootings and active shooter situations has significantly increased at higher education institutions (HEIs) over the past several years, and as a result, they have introduced issues of safety that administrators must handle. The purpose of this embedded, single case study was to understand the attitudes concerning concealed carry on campus for students, staff, and faculty at Liberty University. The primary theory guiding this study was vested interest theory (Crano, 1997) as it examines the attitudes of those most closely involved with a situation and how they become vested in a particular situation which results in behavior …