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Hyperoxia During Neonatal Cardiopulmonary Bypass Is Associated With Worse Clinical Outcomes: A Multi-Institutional Study, Asaad G Beshish, David M Kwiatkowski, Nathaniel Sznycer-Taub, John M Costello, Andrew Jergel, Scott Gillespie, Katherine Cashen, Ahmed Asfari, Maria Batsis, Jason R Buckley, Meghan M Chlebowski, Saul Flores, Nimrod Goldshtrom, Karl Migally, Kimberly I Mills, Monique R Radman, Chetana Reddy, Brittany Shutes, Christine M Riley, Sukumar Suguna Narasimhulu, Dana Mueller, Venugopal Amula, Raji Venkitachalam, Brian F Joy, Karan B Karki, Scott M Leopold, Jennifer E Schramm, Christine A Capone, Scott I Aydin, Adnan M Bakar, Kieran Leong, Agnieszka Kulikowska, Sarah Wing, Christopher W Mastropietro, Collaborative Research From The Pediatric Intensive Care Society (Core‐Pcics) Investigators Nov 2025

Hyperoxia During Neonatal Cardiopulmonary Bypass Is Associated With Worse Clinical Outcomes: A Multi-Institutional Study, Asaad G Beshish, David M Kwiatkowski, Nathaniel Sznycer-Taub, John M Costello, Andrew Jergel, Scott Gillespie, Katherine Cashen, Ahmed Asfari, Maria Batsis, Jason R Buckley, Meghan M Chlebowski, Saul Flores, Nimrod Goldshtrom, Karl Migally, Kimberly I Mills, Monique R Radman, Chetana Reddy, Brittany Shutes, Christine M Riley, Sukumar Suguna Narasimhulu, Dana Mueller, Venugopal Amula, Raji Venkitachalam, Brian F Joy, Karan B Karki, Scott M Leopold, Jennifer E Schramm, Christine A Capone, Scott I Aydin, Adnan M Bakar, Kieran Leong, Agnieszka Kulikowska, Sarah Wing, Christopher W Mastropietro, Collaborative Research From The Pediatric Intensive Care Society (Core‐Pcics) Investigators

Faculty, Staff and Students Publications

Background: Exposure to supraphysiologic oxygen concentrations, or hyperoxia, during neonatal cardiopulmonary bypass (CPB) has been associated with worse outcomes in single-center studies. We aimed to describe variation in oxygen exposure during CPB and determine if hyperoxia is associated with worse outcomes in a multicenter cohort of neonates undergoing cardiac surgery.

Methods: We conducted a retrospective study of neonates who underwent surgery with CPB between January 2021 and December 2022 at 29 centers. Primary outcomes were operative mortality and major adverse cardiovascular events (MACE), which included CPR, extracorporeal support, stroke, and mortality. Logistic regression assessed the associations between median PaO2 during …


Glucagon-Like Peptide 1 Receptor Agonists And The Clinical Outcomes Of Inflammatory Bowel Disease: A Systematic Review And Meta-Analysis, Ahmed B Bayoumy, Lindsay M Clarke, Parakkal Deepak, Aakash Desai, Priya Sehgal, Uri Gorelik, Haggai Bar-Yoseph, Marie Villumsen, Chris J J Mulder, Dirk J Stenvers, Maarten E Tushuizen, Nanne K H De Boer Nov 2025

Glucagon-Like Peptide 1 Receptor Agonists And The Clinical Outcomes Of Inflammatory Bowel Disease: A Systematic Review And Meta-Analysis, Ahmed B Bayoumy, Lindsay M Clarke, Parakkal Deepak, Aakash Desai, Priya Sehgal, Uri Gorelik, Haggai Bar-Yoseph, Marie Villumsen, Chris J J Mulder, Dirk J Stenvers, Maarten E Tushuizen, Nanne K H De Boer

2020-Current year OA Pubs

BACKGROUND: Prior studies showed worse outcomes in obese inflammatory bowel disease (IBD) patients, especially those related to hospitalizations, surgery, and steroid-free remission. Glucagon-like peptide-1 receptor agonists (GLP1-RAs) have demonstrated significant metabolic benefits for patients with type 2 diabetes mellitus (T2DM) and obesity. Hence, GLP1-RAs may improve clinical outcomes in patients with IBD, especially those with obesity. The objective was to systematically evaluate the impact of GLP1-RAs on clinical outcomes in patients with IBD.

METHODS: A comprehensive literature search was performed using the databases PubMed, Embase, Web of Science, and Cochrane Library from inception to March 15, 2025. Studies reporting outcomes …


Correlation With Car Density In Urban Environments And Its Influence On Chronic Obstructive Pulmonary Disease (Copd) Rates In The United States, Daniel Barreiro-Torres, Kedai Cheng Nov 2025

Correlation With Car Density In Urban Environments And Its Influence On Chronic Obstructive Pulmonary Disease (Copd) Rates In The United States, Daniel Barreiro-Torres, Kedai Cheng

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Parameter Estimation And Simulation In Pollution-Induced Asthma Disease Model Using Physics-Informed Neural Networks, Aadi Gannavaram Nov 2025

Parameter Estimation And Simulation In Pollution-Induced Asthma Disease Model Using Physics-Informed Neural Networks, Aadi Gannavaram

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Spatial Model For Oyster Reef Growth With Sediment Interactions, Merryn E. Grindstaff Nov 2025

Spatial Model For Oyster Reef Growth With Sediment Interactions, Merryn E. Grindstaff

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Understanding The Spread Of Black Sigatoka Disease: A Deterministic And Stochastic Modeling Approach, Bernard Asamoah Afful, Luis F. Gordillo Nov 2025

Understanding The Spread Of Black Sigatoka Disease: A Deterministic And Stochastic Modeling Approach, Bernard Asamoah Afful, Luis F. Gordillo

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling Sickle Cell Disease Using A Sleep-Pain-Inflammation Cycle, Milan Marsh Nov 2025

Modeling Sickle Cell Disease Using A Sleep-Pain-Inflammation Cycle, Milan Marsh

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling The Probability Of N Clonal Rosettes In A Bromeliaceae Genetic Individual, Erin N. Bodine, Layla K. Lammers Nov 2025

Modeling The Probability Of N Clonal Rosettes In A Bromeliaceae Genetic Individual, Erin N. Bodine, Layla K. Lammers

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Impacts Of Metapopulation Structure On Infectious Disease Dynamics, Éowyn M. Poplawski, David Brown Nov 2025

The Impacts Of Metapopulation Structure On Infectious Disease Dynamics, Éowyn M. Poplawski, David Brown

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling And Analysis Of The Impacts Of The Rise In Ai Use On Data Center Growth, Resulting Workforce Displacement, And Environmental Impacts Through A Coupled System Of Ordinary Differential Equations Within A Feedback Framework, Divya Laddha, Alonso Gabriel Ogueda, Padmanabhan Seshaiyer Nov 2025

Modeling And Analysis Of The Impacts Of The Rise In Ai Use On Data Center Growth, Resulting Workforce Displacement, And Environmental Impacts Through A Coupled System Of Ordinary Differential Equations Within A Feedback Framework, Divya Laddha, Alonso Gabriel Ogueda, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Using Compartmental Systems Of Ordinary Differential Equations And Optimal Control Theory To Compute Ideal Quantities Of Mentors For Student Populations, Timofey B. Gafurov Nov 2025

Using Compartmental Systems Of Ordinary Differential Equations And Optimal Control Theory To Compute Ideal Quantities Of Mentors For Student Populations, Timofey B. Gafurov

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling Probiotic Bacterial Control Of White-Nose Syndrome In Little Brown Bat Colonies, Bethany Droubay, Alex Capaldi Nov 2025

Modeling Probiotic Bacterial Control Of White-Nose Syndrome In Little Brown Bat Colonies, Bethany Droubay, Alex Capaldi

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


A Compartmental Model For Diurnal Atlantic Stingray Migration, Rhianna Yates, Leah Glasser, Elena Wheatley, Christopher Hay-Jahans Nov 2025

A Compartmental Model For Diurnal Atlantic Stingray Migration, Rhianna Yates, Leah Glasser, Elena Wheatley, Christopher Hay-Jahans

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematically Modeling Stoichiometric Drivers Of Heterotrophic N2 Fixation, Corday R. Selden, Rebecca Everett, Halvor H. Halvorson, Megan E. Berberich, Luca Schenone, Angela Peace, Renn Schipper, Edwin Cruz-Rivera, James Powell, Keisuke Inomura, Robinson W. Fulweiler, Amy M. Marcarelli, J Thad Scott Nov 2025

Mathematically Modeling Stoichiometric Drivers Of Heterotrophic N2 Fixation, Corday R. Selden, Rebecca Everett, Halvor H. Halvorson, Megan E. Berberich, Luca Schenone, Angela Peace, Renn Schipper, Edwin Cruz-Rivera, James Powell, Keisuke Inomura, Robinson W. Fulweiler, Amy M. Marcarelli, J Thad Scott

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


A Compartmental Model For Annual Bat Migration, Elena D. Wheatley, Rhianna Yates, Leah Glasser, Christopher Hay-Jahans Nov 2025

A Compartmental Model For Annual Bat Migration, Elena D. Wheatley, Rhianna Yates, Leah Glasser, Christopher Hay-Jahans

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling The Impact Of Treatment During An Ongoing Tuberculosis Outbreak, Bach Le, Jude Shive, Erin N. Bodine Nov 2025

Modeling The Impact Of Treatment During An Ongoing Tuberculosis Outbreak, Bach Le, Jude Shive, Erin N. Bodine

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Analyzing Urban Space-Use Of White-Tailed Deer (Odocoileus Virginianus), Szandra A. Péter, Zehidul Hussain, Solena Kronstedt, Amira Roess, Jennifer Mullinax, Travis Gallo, Taylor Anderson Nov 2025

Analyzing Urban Space-Use Of White-Tailed Deer (Odocoileus Virginianus), Szandra A. Péter, Zehidul Hussain, Solena Kronstedt, Amira Roess, Jennifer Mullinax, Travis Gallo, Taylor Anderson

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling, Analysis And Simulation With Optimal Control Applied To Malnutrition, Dia Bonsu Nov 2025

Modeling, Analysis And Simulation With Optimal Control Applied To Malnutrition, Dia Bonsu

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Balancing Stability And Complexity In Boolean Models Of Biological Networks, Venkata Sai Narayana Bavisetty Nov 2025

Balancing Stability And Complexity In Boolean Models Of Biological Networks, Venkata Sai Narayana Bavisetty

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling, Analysis And Simulation To Study The Multi-Stage Dynamics Of Student Debts, Paula Navarro Ortiz, Nathan Bezabeh Nov 2025

Modeling, Analysis And Simulation To Study The Multi-Stage Dynamics Of Student Debts, Paula Navarro Ortiz, Nathan Bezabeh

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


A Compartmental Model For Periodic Animal Migration, Rhianna Yates, Leah Glasser, Elena Wheatley, Christopher Hay-Jahans Nov 2025

A Compartmental Model For Periodic Animal Migration, Rhianna Yates, Leah Glasser, Elena Wheatley, Christopher Hay-Jahans

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


A Compartmental Model For Annual Blue Whale Migration, Leah Glasser, Christopher Hay-Jahans, Elena Wheatley, Rhianna Yates Nov 2025

A Compartmental Model For Annual Blue Whale Migration, Leah Glasser, Christopher Hay-Jahans, Elena Wheatley, Rhianna Yates

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Spatial Strategies In Ants: Modeling Polydomy, Saya Zeleznik, Fred Adler Nov 2025

Spatial Strategies In Ants: Modeling Polydomy, Saya Zeleznik, Fred Adler

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Optimizing The Distribution Of Fruiting Agave On Bat-Friendly Tequila Plantations, Grace Gorreck, Clarissa Azurin, Lois Carpenter Nov 2025

Optimizing The Distribution Of Fruiting Agave On Bat-Friendly Tequila Plantations, Grace Gorreck, Clarissa Azurin, Lois Carpenter

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling Self-Organizing Networks In Life Sciences And Beyond, Nina H. Fefferman Nov 2025

Modeling Self-Organizing Networks In Life Sciences And Beyond, Nina H. Fefferman

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Predicting An Uncertain Future: Conservation Easements And The Difficulties Created By Speculative Valuations, Travis L. Strickler Nov 2025

Predicting An Uncertain Future: Conservation Easements And The Difficulties Created By Speculative Valuations, Travis L. Strickler

Kentucky Law Journal

No abstract provided.


The Cost Of Our Constitutional Rights: An Examination Of Prison Medical Treatment For Hepatitis-C, M. Abigail Schueler Nov 2025

The Cost Of Our Constitutional Rights: An Examination Of Prison Medical Treatment For Hepatitis-C, M. Abigail Schueler

Kentucky Law Journal

No abstract provided.


The Interpretive Foundations Of Arbitrary Or Capricious Review, Alexander Mechanick Nov 2025

The Interpretive Foundations Of Arbitrary Or Capricious Review, Alexander Mechanick

Kentucky Law Journal

No abstract provided.


Crony Stakeholder Capitalism, Stefan J. Padfield Nov 2025

Crony Stakeholder Capitalism, Stefan J. Padfield

Kentucky Law Journal

No abstract provided.


Age Is More Than Just A Number: A Legal And Ethical Defense Of Age-Based Triage Protocols, Jessica Mantel Nov 2025

Age Is More Than Just A Number: A Legal And Ethical Defense Of Age-Based Triage Protocols, Jessica Mantel

Kentucky Law Journal

No abstract provided.