Digital Commons Network^™

The Evolution And Future Prospects Of Ionizing Radiation Protection Training For Dentists In Taiwan, Feng-Chou Cheng, Yu-Min Lin, Mu-Hsiung Chen, Chun-Pin Chiang

Journal of Dental Sciences

No abstract provided.

Bio-Obturation Of A Large Perforated Internal Root Resorption: A Case Report, Saeed Asgary

Journal of Dental Sciences

No abstract provided.

Exploring Existing Methods For Calculating Dental Arch Form And Curvature, Li-Tong Zheng, Sheng-Yang Lee, Yu-Chieh Lin, Wei-Chun Lin

Journal of Dental Sciences

No abstract provided.

Current Challenges Of Safety Management And Supervision For The Dental Radiology Diagnosis Equipment In Taiwan, Feng-Chou Cheng, Mu-Hsiung Chen, Sheau-Jing Yu, Chun-Pin Chiang

Journal of Dental Sciences

No abstract provided.

Successful Non-Surgical Repair Of A Large Furcal Perforation Using Endodontic Biomaterials: A Case Report Of 30-Month Follow-Up, Saeed Asgary

Journal of Dental Sciences

No abstract provided.

Complicated Management Of A Surgical Site Infection Following Open Reduction And Internal Fixation Of A Mandibular Condylar Fracture In A Patient With Multiple Antibiotic Allergies, Keigo Maeda, Shinsuke Yamamoto, Naoki Taniike

Journal of Dental Sciences

No abstract provided.

Management Of An Endodontic Lesion With Secondary Periodontal Ligament Changes In An Adjacent Tooth Following Root Perforation: Two-Year Follow-Up, Saeed Asgary

Journal of Dental Sciences

No abstract provided.

Geographical Distribution Of Hometowns Of Female Dental Graduates From Toyo Girls Dental College In Japan In 1932, Feng-Chou Cheng, Ling-Hsia Wang, Shiang-Yao Liu, Chun-Pin Chiang

Journal of Dental Sciences

No abstract provided.

Rethinking English Medium Instruction For Dental Education In Taiwan, Ching-Shuen Wang, Feng-Chou Cheng, Wei-Chun Lin, Chun-Pin Chiang

Journal of Dental Sciences

No abstract provided.

Pleomorphic Adenoma With Extensive Squamous Metaplasia - A Case Report, Hung-Pin Lin, Chun-Pin Chiang

Journal of Dental Sciences

No abstract provided.

The Exploration Of Dental Careers Among High School Girls In Taiwan During The Japanese Colonial Period, Feng-Chou Cheng, Ling-Hsia Wang, Shiang-Yao Liu, Chun-Pin Chiang

Journal of Dental Sciences

No abstract provided.

Dynamic Navigation Method For Rapid Confirmation Of Multi-Unit Abutment Position And Angulation, Han-Wei Lin, Cheng-Chung Lin, Wei-Shao Lin, Wei-Chun Lin

Journal of Dental Sciences

No abstract provided.

Tooth Jewelry In Rural Cambodia: An Unexpected Finding During Dental Volunteer Service, Chuan-Hang Yu

Journal of Dental Sciences

No abstract provided.

Fabricated Citations In The Age Of Ai: A Wake-Up Call For Editors, Reviewers, And Authors, He Liu

Journal of Dental Sciences

No abstract provided.

Oral Health In The Children's Literacy Book “Kuei Pen Tui Hsiang Ssu Yen Tsa Tzu” From The Early Ming Dynasty, Feng-Chou Cheng, Ling-Hsia Wang, Shiang-Yao Liu, Chun-Pin Chiang

Journal of Dental Sciences

No abstract provided.

The Dental Career Development Of Physicians During The Japanese Colonial Period In Taiwan: A Case Study Of Dr. Ying-Fang Chen, Feng-Chou Cheng, Ling-Hsia Wang, Shiang-Yao Liu, Chun-Pin Chiang

Journal of Dental Sciences

No abstract provided.

The Effect Of Photobiomodulation Therapy On Neurosensory Recovery Of Infra-Alveolar Nerve Following Iatrogenic Trauma: A Literature Review, Rashin Bahrami, Maryam Pourhajibagher, Fateme Gharibpour, Amirmorteza Rezazadeh, Abbas Bahador

Journal of Dental Sciences

No abstract provided.

Human Oral Microbiota Dysbiosis May Be A Novel Non-Invasive Indicator Of Erectile Dysfunction, Yu Qiao, Fei Mao, Bing-Ru Jiang, Shu-Yan Lv, Heng-Bing Wang, Guang-Bo Fu

Journal of Dental Sciences

No abstract provided.

Risk Of Deep Vein Thrombosis In Patients With Periodontitis: A Nationwide Population-Based Cohort Study In Taiwan, Ying-Ting Yeh, Nai-Chen Shih, Ping-Ju Chen, Yu-Hsun Wang, Chao-Bin Yeh

Journal of Dental Sciences

No abstract provided.

Journal Of Dental Sciences Editorial Board

Journal of Dental Sciences

No abstract provided.

Evaluation Of Condylar Position Displacement Using Various Centric Relation Recording Techniques Based On Maximum Intercuspation Position: A Systematic Review And Meta-Analysis, Ling-Shiuan Huang, Yen-Chang Huang, I-Ting Wu, Shinn-Jyh Ding

Journal of Dental Sciences

Background/ purpose: Restoring tooth defects is a key clinical task for dentists, aimed at either maintaining or reconstructing a functional occlusal dentition. This study conducted a systematic review and meta-analysis of clinical trials comparing centric relation (CR) and maximum intercuspal position (MIP) condylar positions obtained using various CR techniques, and to verify the reproducibility of these methods.

Materials and methods: The PubMed, Embase, Google Scholar, and Cochrane Library databases were searched for articles published before January 2026. The single-arm meta-analysis used a random-effects model to calculate the overall effect size.

Results: This study included 12 articles published …

Dental Treatment And Oral Care For Patients With Severe Mental Illness Receiving Psychiatric Home-Visit Care: A Narrative Review With An Illustrative Case, Takayuki Suga, Trang Thi Huyen Tu, Yuji Gamo, Takafumi Asakura, Shigeru Iida, Akira Toyofuku

Journal of Dental Sciences

Patients with severe mental illness (SMI) often have untreated caries, periodontal inflammation, tooth loss, xerostomia-related risk, dental anxiety, and delayed dental attendance. This narrative review aimed to synthesize evidence relevant to dental treatment planning for patients with SMI receiving psychiatric home-visit care and to clarify when domiciliary dental assessment and repeated professional oral care may be indicated. Targeted literature searches and citation tracking were used to identify reviews, epidemiological studies, intervention studies, qualitative syntheses, and special care dentistry guidance. The evidence indicates that oral disease in SMI reflects not only limited knowledge but also avolition, cognitive impairment, psychosis, sedation, medication-induced …

Efficacy Of Cryotherapy For Oral Leukoplakia: A Systematic Review, Chuan-Hang Yu, Tzu-Chen Chan, Chun-Pin Chiang

Journal of Dental Sciences

Oral leukoplakia (OL) is the most common oral potentially malignant disorder and carries a risk of malignant transformation. Cryotherapy is a minimally invasive treatment option for OL, but its efficacy and optimal dose-response remain inconsistent among various studies. This systematic review evaluated the clinical efficacy and safety of cryotherapy for OL lesions and explored whether the characteristics of the lesions and treatment parameters influenced clinical outcomes. Electronic searches were performed in Embase, PubMed, and the Cochrane Central Register of Controlled Trials according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Seven studies reporting original clinical outcomes of …

Epigallocatechin Gallate In Dentistry: Therapeutic Applications, Biomaterial Integration, And Translational Challenges, Chloe Jui-Yun Chang, Fang-Yu Fan, Yung-Li Wang, Thi Thuy Tien Vo, Yang-Che Wu, Yu-Chia Chang, I-Ta Lee

Journal of Dental Sciences

Epigallocatechin gallate (EGCG), a major bioactive catechin in green tea, has attracted increasing attention in dentistry because of its antioxidant, anti-inflammatory, antimicrobial, matrix-modulating, and regenerative properties. This narrative review summarizes current evidence on the biological mechanisms, dental applications, and translational challenges of EGCG in oral healthcare. EGCG can modulate oxidative stress and inflammatory signaling pathways, including nuclear factor-kB (NF-kB), mitogen-activated protein kinase (MAPK), nuclear factor erythroid 2-related factor 2/heme oxygenase-1 (Nrf2/HO-1), and NOD-like receptor family pyrin domain containing 3 (NLRP3)-related responses, and has activity against oral disease-associated microorganisms and biofilms. In periodontal therapy, EGCG has been investigated as an adjunct …

Higher Serum Gastric Parietal Cell Antibody Titers Are Associated With Increased Frequencies Of Macrocytosis, Vitamin B12 Deficiency, And Hyperhomocysteinemia In Patients With Oral Lichen Planus, Yu-Hsueh Wu, Yi-Pang Lee, Julia Yu-Fong Chang, Yi-Ping Wang, Andy Sun, Chun-Pin Chiang

Journal of Dental Sciences

Background/purpose: Our previous study found 139 gastric parietal cell antibody (GPCA)-positive oral lichen planus (OLP) patients (GPCA⁺OLP patients) in a group of 588 OLP patients. This study evaluated whether higher-titer (serum GPCA titer ≥ 160) GPCA⁺OLP patients had greater frequencies of macrocytosis, anemia, serum iron and vitamin B12 deficiencies, and hyperhomocysteinemia than lower-titer (GPCA titer ≤ 80) GPCA⁺OLP patients or 588 healthy control subjects.

Materials and methods: Complete blood count, serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 53 higher-titer GPCA⁺OLP patients, 86 lower-titer GPCA⁺OLP patients, and …

Oral Pathogens Reprogram Endothelial Barrier And Angiotensin-Converting Enzyme2/Endothelial Nitric Oxide Synthase-Nitric Oxide Signaling To Promote Blood Pressure Dysregulation, Ming-Shou Hsieh, Tung-Nien Hsu, Chin-Sheng Huang, Ting-Yi Renn, Kuang-Tai Kuo, Kuo-Yao Lin, Wei Jen Chang

Journal of Dental Sciences

Background/purpose: Although periodontal disease is associated with an increased risk of hypertension, the endothelial mechanisms linking oral inflammation to vascular dysfunction remain unclear. We investigated whether Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) can directly disturb endothelial homeostasis and whether macrophage–endothelial crosstalk further worsens endothelial injury.

Materials and methods: Human umbilical vein endothelial cells (HUVECs) were exposed to Pg-LPS alone or co-cultured (transwell system) with Pg-LPS-primed human monocytic cells -derived macrophages. Endothelial dysfunction was assessed through nitric oxide (NO) production, endothelial nitric oxide synthase (eNOS) phosphorylation, inflammatory and adhesion molecule expression, as well as junctional and cytoskeletal changes. Macrophage …

Dental Age–Based Assessment Of Retromolar Morphology In Skeletal Class Iii Patients: Implications For Mandibular Third Molar Development, Thuy-Trang Thi Ho, Tu Manh Nguyen, Loc Minh Lu, Fang-Yu Fan, Ying-Sui Sun, Yang-Che Wu, Sheng-Wei Feng, Chien-Fu Tseng, Pao-Chang Chiang, I-Ta Lee

Journal of Dental Sciences

Background/purpose: In skeletal Class III malocclusion, evaluation of mandibular third molar development is clinically important for orthodontic treatment planning, particularly in relation to posterior space conditions. This study aimed to assess the association between dental age of mandibular third molars and retromolar morphological characteristics in skeletal Class III patients.

Materials and methods: This retrospective cross-sectional study included panoramic radiographs from 157 patients diagnosed with skeletal Class III malocclusion based on clinical examination and lateral cephalometric analysis. Mandibular third molar development was evaluated using Demirjian mineralization stages (D–H), representing stages from crown completion to root maturation. Retromolar morphology was evaluated …

Endothelin-1 Drives Cyclooxygenase-2 And Prostaglandin E2 Expression In Osteoblasts Through Mitogen-Activated Protein Kinase And Activator Protein-1 Signaling During Periodontal Inflammation, Fang-Yu Fan, Thi Thuy Tien Vo, Hsuan Kuo, Chien-Fu Tseng, Wei-Ning Lin, Chia-Yu Wu, Yang-Che Wu, Chuen-Mao Yang, Li-Der Hsiao, I-Ta Lee

Journal of Dental Sciences

Background/purpose: Endothelin-1 (ET-1) has been implicated in inflammatory tissue responses, but its role in osteoblast-mediated inflammation during periodontal inflammation remains unclear. This study investigated whether ET-1 induces cyclooxygenase-2 (COX-2) expression and prostaglandin E₂ (PGE₂) release in osteoblasts and explored the underlying signaling mechanisms.

Materials and methods: Murine osteoblast-like MC3T3-E1 cells were stimulated with ET-1. COX-2 protein and mRNA expression, promoter activity, and PGE₂ release were assessed by Western blotting, real-time RT-PCR, luciferase reporter assay, and ELISA, respectively. Pharmacological inhibitors and siRNA knockdown were used to examine the roles of ET_A/ET_B receptors, G_{q …}

Cephalometric And Soft Tissue Determinants Of Esthetic Outcomes After Single-Jaw Mandibular Setback Surgery In Skeletal Class Iii Patients: A Retrospective Study, Chun-Te Ho, You-Ru Chen, Tsui-Hsien Huang, Jnug-Chun Yeh, Tzu-Yu Peng, Chia-Tze Kao

Journal of Dental Sciences

Background/purpose: Orthognathic surgery is an effective treatment for skeletal Class III malocclusion; however, the relative influence of skeletal and soft tissue variables on postoperative esthetic outcomes remains unclear. This study aimed to evaluate the relationships among cephalometric parameters, soft tissue changes, and esthetic outcomes following single-jaw mandibular setback surgery.

Materials and methods: A retrospective study was performed on 258 adult patients with skeletal Class III malocclusion subspinale-nasion-supramentale (ANB) angle < 0° who were treated between 2016 and 2021. Patients were divided into three groups: bilateral vertical ramus osteotomy (BVRO) group (n = 99), genioplasty alone group (n = 30), and BVRO plus genioplasty group. (n = 129). Cephalometric and …

Isoliquiritigenin Represses The Pro-Fibrotic Tgf-Β/Smad2 Signaling And Nuclear Enriched Abundant Transcript 1 (Neat1) In Oral Submucous Fibrosis, Chi-Shan Tseng, Shih-Min Wang, Yi-Wen Liao, Her-Hsiung Huang, Cheng-Chia Yu, Yicyuan Chen

Journal of Dental Sciences

Background/purpose: Isoliquiritigenin (ISL) has shown anti-fibrotic potential in several organ systems, but its effects on oral submucous fibrosis (OSF) remain unclear. This study investigated whether ISL attenuates myofibroblast activities in buccal mucosal fibroblasts (BMFs) from OSF patients by modulating TGF-β/Smad2 signaling and the long non-coding RNA NEAT1.

Materials and methods: Primary normal BMFs and fibrotic BMFs (fBMFs) were isolated from human buccal mucosa, and cell viability, collagen gel contraction, migration, and wound closure were examined after ISL treatment with or without arecoline. TGF-β1 secretion was quantified, while protein expression of phosphorylated Smad2, COL1A1, and α-SMA was analyzed, and …