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Griffin: Effective Token Alignment For Faster Speculative Decoding, Shijing Hu, Jingyang Li, Xingyu Xie, Zhihui Lu, Kim-Chuan Toh, Pan Zhou Dec 2025

Griffin: Effective Token Alignment For Faster Speculative Decoding, Shijing Hu, Jingyang Li, Xingyu Xie, Zhihui Lu, Kim-Chuan Toh, Pan Zhou

Research Collection School Of Computing and Information Systems

Speculative decoding accelerates inference in large language models (LLMs) by generating multiple draft tokens simultaneously. However, existing methods often struggle with token misalignment between the training and decoding phases, limiting their performance. To address this, we propose GRIFFIN, a novel framework that incorporates a token-alignable training strategy and a token-alignable draft model to mitigate misalignment. The training strategy employs a loss masking mechanism to exclude highly misaligned tokens during training, preventing them from negatively impacting the draft model’s optimization. The token-alignable draft model introduces input tokens to correct inconsistencies in generated features. Experiments on LLaMA, Vicuna, Qwen and Mixtral models …


Sheetpedia: A 300k-Spreadsheet Corpus For Spreadsheet Intelligence And Llm Fine-Tuning, Zailong Tian, Zhuoheng Han, Houfeng Wang, Lizi Liao Dec 2025

Sheetpedia: A 300k-Spreadsheet Corpus For Spreadsheet Intelligence And Llm Fine-Tuning, Zailong Tian, Zhuoheng Han, Houfeng Wang, Lizi Liao

Research Collection School Of Computing and Information Systems

Spreadsheets are widely used for data analysis and reporting, yet their complex structure and formula logic pose significant challenges for AI systems. We introduce Sheetpedia, a large-scale corpus of over 290,000 diverse spreadsheets (from 324,000+ workbooks) compiled from enterprise email archives and online forums. We detail a rigorous collection and preprocessing pipeline (integrating the Enron email spreadsheet archive and the Fuse web corpus, plus a new crawl of Excel forums) to standardize formats, filter languages, and remove duplicates. Sheetpedia provides extensive coverage of real formulas and annotations – addressing a gap left by prior table datasets (e.g. web tables used …


When Less Language Is More: Language-Reasoning Disentanglement Makes Llms Better Multilingual Reasoners, Weixiang Zhao, Jiahe Guo, Yang Deng, Tongtong Wu, Wenxuan Zhang, Yulin Hu, Xingyu Sui, Yanyan Zhao, Wanxiang Che, Bing Qin, Tat-Seng Chua, Ting Liu Dec 2025

When Less Language Is More: Language-Reasoning Disentanglement Makes Llms Better Multilingual Reasoners, Weixiang Zhao, Jiahe Guo, Yang Deng, Tongtong Wu, Wenxuan Zhang, Yulin Hu, Xingyu Sui, Yanyan Zhao, Wanxiang Che, Bing Qin, Tat-Seng Chua, Ting Liu

Research Collection School Of Computing and Information Systems

Multilingual reasoning remains a significant challenge for large language models (LLMs), with performance disproportionately favoring high-resource languages. Drawing inspiration from cognitive neuroscience, which suggests that human reasoning functions largely independently of language processing, we hypothesize that LLMs similarly encode reasoning and language as separable components that can be disentangled to enhance multilingual reasoning. To evaluate this, we perform a causal intervention by ablating language-specific representations at inference time. Experiments on 10 open-weight LLMs spanning 11 typologically diverse languages show that this language-specific ablation consistently boosts multilingual reasoning performance. Layer-wise analyses further confirm that language and reasoning representations can be effectively …


Building Kit For K-8 Education: An Introduction To Construction Fundamentals, Marc Joynt Dec 2025

Building Kit For K-8 Education: An Introduction To Construction Fundamentals, Marc Joynt

Construction Management

Introducing construction concepts to young students requires tools that are both engaging and easy to use, which led to the development of a laser-cut building kit designed for K–8 classrooms. The process began with hand-drawn sketches to establish a simple, age-appropriate structure. The design was then modeled in AutoCAD, where each individual component was drafted for fabrication. After completing the digital model, the files were transferred into Rhino and organized by layer to ensure accurate communication with the laser cutters used to produce the final basswood pieces. Throughout the project, challenges such as material limitations, tolerance adjustments, and simplifying complex …


Strategic Interactions And Gender Cues: Evidence From Social Preference Games, Hernán Bejarano, Matias Busso, Juan Francisco Santos Dec 2025

Strategic Interactions And Gender Cues: Evidence From Social Preference Games, Hernán Bejarano, Matias Busso, Juan Francisco Santos

ESI Working Papers

This paper studies trust, reciprocity, and bargaining using a large-scale online experiment conducted in six Latin American countries. Participants played trust and ultimatum games under randomly assigned conditions in which the gender of their counterpart was either disclosed or withheld. On average, disclosing counterpart gender does not yield statistically detectable effects in either game. However, statistically significant differences emerge by participants' own gender: on average men exhibit higher levels of trust, reciprocity, and generosity in bargaining than women. When disaggregating by participant-counterpart gender pairings, point estimates differ in sign across groups but are generally imprecisely estimated, and differences between interacting …


Involvement Of Students With Extensive Support Needs In Pbis: Middle School Educator And Administrator Perspectives, Virginia L. Walker, Megan E. Carpenter, Sheldon Loman Dec 2025

Involvement Of Students With Extensive Support Needs In Pbis: Middle School Educator And Administrator Perspectives, Virginia L. Walker, Megan E. Carpenter, Sheldon Loman

Journal of Case Learning & Exceptional Learners

School-wide positive behavioral interventions and supports (PBIS) is a widely adopted multi-tiered system of behavioral supports designed to promote a safe, predictable, and inclusive school environment for all students. Despite the positive outcomes associated with PBIS, students with extensive support needs (ESN) may have limited access to and involvement in all aspects of PBIS. In this article, we describe the perspectives of three staff members––an administrator, general education teacher, and special education teacher––who participated in interviews about the involvement of students with ESN in PBIS. These staff members provided insightful information about how students with ESN were involved in PBIS …


Studies Of Trispyrazolylborate Molybdenum-Oxo Compounds And Related Reactions, Miranda Sanders Dec 2025

Studies Of Trispyrazolylborate Molybdenum-Oxo Compounds And Related Reactions, Miranda Sanders

Graduate Theses and Dissertations

This dissertation details the design, development, and synthesis of a molybdenum-dioxo complex bearing a trispyrazolylborate ligand. The system was tested for its efficiency as a catalyst for deoxydehydration with a small substrate scope. Deoxydehydration reactions with 1-phenyl-1,2-ethanediol, diethytartrate, and 1,2-octanediol show low yields with catalytic turnover only found for diethyltartrate. Electrochemical studies show well behaved PCET behavior with two distinct electron transfer events in the presence of a proton donor. Studies of two molybdenum-dioxo complexes bearing dianionic pincer ligands were conducted to expand further on systems that have been extensively studied in our lab. Deoxydehydration of glycerol by a molybdenum-dioxo …


Perception Of Drinking Water Quality Among Arkansas Residents, Kolade Olawale Olatunde Dec 2025

Perception Of Drinking Water Quality Among Arkansas Residents, Kolade Olawale Olatunde

Graduate Theses and Dissertations

Objective: Perceptions of drinking water quality influence public trust, water consumption behaviors, and the willingness to invest in infrastructure improvements. Despite the importance of safe drinking water, regional and socio-economic disparities impact how residents perceive their tap water and their readiness to pay for enhancements. While past research indicates that negative views of tap water quality have resulted in behavioral changes, the connection between perception and actual household water usage remains ambiguous. This study aims to investigate how perceptions of drinking water quality differ across regions in Arkansas and how residents are willing to invest in quality improvements. Method: A …


Fungicidal Management Of Spring Dead Spot Using Improved Modeling And Application Strategies, Michael Vincent Battaglia Dec 2025

Fungicidal Management Of Spring Dead Spot Using Improved Modeling And Application Strategies, Michael Vincent Battaglia

Graduate Theses and Dissertations

Spring dead spot (SDS) is a destructive disease of bermudagrass (Cynodon Rich. spp.) in parts of the world that experience winter dormancy. Fungicides are often necessary to properly manage SDS, and significant research has been conducted to improve fungicidal effectiveness. Several studies were conducted with the objectives of improving fungicide application timing, method of fungicide application, and long-term fungicidal efficiency. In the fungicide application study, a cooling degree-day (CDD) model based on soil temperatures was developed. The CDD model showed that isofetamid was highly effective against SDS during a wide application window in autumn, while tebuconazole was inconsistently effective and …


A Phenomenological Exploration Of Black International Graduate Students’ Experiences In Building A Sense Of Belonging And Community At A Predominantly White Southern University, Hilda Solange George Dec 2025

A Phenomenological Exploration Of Black International Graduate Students’ Experiences In Building A Sense Of Belonging And Community At A Predominantly White Southern University, Hilda Solange George

Graduate Theses and Dissertations

Black international graduate students’ experiences navigating and developing a sense of belonging and community at higher educational institutions in the United States and particularly at predominantly white institutions have received minimal attention in scholarly inquiries, despite their cultural, intellectual, and financial contributions to host institutions and the country. To fill this gap in the existing literature, this hermeneutical phenomenological study aimed to gain a nuanced and in-depth understanding of Black international graduate students' perceptions of their sense of belonging and community at a predominantly white southern university (PWSU) in the United States. Guided by the research questions and the Black …


Effects Of Injectable Trace Mineral Timing On Calf Performance And Health Indicators, Marie E. Goulais Dec 2025

Effects Of Injectable Trace Mineral Timing On Calf Performance And Health Indicators, Marie E. Goulais

Graduate Theses and Dissertations

One hundred and fourteen calves (average BW= 224kg ± 89kg) were utilized to evaluate the effects of injectable trace mineral (ITM) administration on calf performance and health when administered pre-weaning and at weaning. Calves were blocked by sex, stratified by age, and randomly assigned to one of the following treatment groups: 1) no ITM injection (CON), 2) ITM administered 28 d before weaning (PW), or 3) ITM administration at weaning (WEAN). Calves were vaccinated against respiratory pathogens on D-28 and D0. At weaning, cattle were transported to a local auction market, held overnight and returned the following morning. Body weight …


Optimizing Cobb Mx X 500 Broiler Diets Through The Investigation Of Lysine And Energy Synergies, Soybean Processing “Add-Backs” Ingredients, And Soybean Genotype Amino Acid Selection, Savannah Caroline Wells Dec 2025

Optimizing Cobb Mx X 500 Broiler Diets Through The Investigation Of Lysine And Energy Synergies, Soybean Processing “Add-Backs” Ingredients, And Soybean Genotype Amino Acid Selection, Savannah Caroline Wells

Graduate Theses and Dissertations

This dissertation explored strategies to optimize Cobb MX x 500 broiler chicken nutrition by investigating lysine and energy synergies, the utilization of soybean processing by-products (“add-backs”), and soybean genotype selection for enhanced amino acid composition. Three independent but complementary research objectives were pursued to improve feed efficiency, sustainability, and cost-effectiveness in modern broiler production. The first objective assessed the interactive effects of dietary lysine and metabolizable energy (ME) on the performance and carcass traits of Cobb MX × 500 broilers. Using a central composite design, nine dietary treatments were formulated across multiple feeding phases. Results demonstrated that broiler performance responded …


Understanding Outer Solar System Ice Composition Through Impact Processes: Simulations And Hydrates, Jill Rebecca Mcdonald Dec 2025

Understanding Outer Solar System Ice Composition Through Impact Processes: Simulations And Hydrates, Jill Rebecca Mcdonald

Graduate Theses and Dissertations

This work concerns solar system ices, particularly water ice and clathrate hydrates. Water ice is abundant as a mineral in the outer parts of the solar system, providing source material for the formation of clathrates. We explored constituents through a combination of numerical modeling and laboratory experiments. Understanding the differences and similarities between these materials can shed light on planetary habitability, composition, and evolution. Chapter one contains relevant background information. This chapter introduces the ices that will be studied and gives insight into the locations of interest within our solar system. It also explains the mechanics of impact cratering processes …


Novel Approaches To Disinfecting Poultry Processing Wastewater For Reuse, Seth Olorunmijuwonlo Adesope Dec 2025

Novel Approaches To Disinfecting Poultry Processing Wastewater For Reuse, Seth Olorunmijuwonlo Adesope

Graduate Theses and Dissertations

Water is an essential resource used in poultry processing, generating large volumes of foodborne pathogen-rich wastewater posing treats to public health. Treating poultry processing wastewater (PPW) is crucial for safe water reuse and sustainable development. Conventional disinfection methods like aerobic digestion and chlorination, although effective, impose considerable operational cost and generate harmful by-products. Integrated recycling systems such as advanced oxidation processes (AOPs) which destroy micro-organisms through the generation of reactive oxygen species (ROS) present a promising opportunity for enhancing resources and sustainability. This study investigated the use of photo-electrochemical (PEC), specifically by combining electrochemical (EC) and photochemical (PC; Photosensitizer and …


Transcriptomic And Contractile Adaptations In Skeletal Muscle In A Rodent Model Of Anorexia Nervosa, Oscar Armando Vicen Dec 2025

Transcriptomic And Contractile Adaptations In Skeletal Muscle In A Rodent Model Of Anorexia Nervosa, Oscar Armando Vicen

Graduate Theses and Dissertations

BACKGROUND: Anorexia Nervosa (AN) is a psychiatric disorder marked by severe chronic caloric restriction and is primarily diagnosed through psychological and behavioral symptoms. AN has the highest mortality of any psychiatric disorder with an increased risk of all-cause mortality. Many individuals with a history of AN experience incomplete recovery despite intervention treatment. Skeletal muscle molecular mechanisms under chronic energy deprivation remain poorly understood. PURPOSE: To investigate transcriptomic profiles of the gastrocnemius muscle following one month of a rodent model of AN. This study analyzed whether the molecular changes correlate with collected muscular force data to provide a comprehensive understanding of …


National Hero And Water Deity: The Worship Of Triệu Việt Vương In The Red River Delta, Vietnam, Huong Thi Nguyen Dec 2025

National Hero And Water Deity: The Worship Of Triệu Việt Vương In The Red River Delta, Vietnam, Huong Thi Nguyen

Graduate Theses and Dissertations

In my dissertation, the theory of collective memory will be deployed to address many questions regarding retaining, recovering, and re-creating the worship of King Triệu Việt Vương. He was a legendary, historical king of Vietnam who supposedly lived in the 6th century. His achievements were connected to the people living in the Red River Delta in their fight against the Liang invasion. The villagers who lived near or in this area also honored him for his spiritual power. They built a small temple/ shrine right by the riverbank to worship this King. The Vietnamese dynasties, Ly (in the 11th century), …


Ring-Opening And Monofunctionalization Study On Spiro Cyclic Aminals And N, O-Acetals System Via Nitrogen-Centered Radical Intermediates, Chujun Zhou Dec 2025

Ring-Opening And Monofunctionalization Study On Spiro Cyclic Aminals And N, O-Acetals System Via Nitrogen-Centered Radical Intermediates, Chujun Zhou

Graduate Theses and Dissertations

The nitrogen-centered radical has been drawing increasing attention among researchers. Radical polarity is one of the key factors in studying nitrogen-centered radicals’ reactivity, and the functional groups attached to the nitrogen atom are of vital importance. Among different types of nitrogen-centered radicals, aminium radical and metal aminium radical are electrophilic due to the positive charge on the intermediate. The sulfonamide radical, amidyl radical, and cyanide amine radical are also electrophilic since the nitrogen is adjacent to electron electron-withdrawing group. The neutral amino radical, iminyl radical, masked nitrogen radical are nucleophilic because of the electron-donating groups. After classifying the nitrogen-centered radical, …


Reading Between Lines: Mapping El Orinoco Ilustrado, Guillermo Pupo Pernet Dec 2025

Reading Between Lines: Mapping El Orinoco Ilustrado, Guillermo Pupo Pernet

Graduate Theses and Dissertations

This dissertation examines El Orinoco Ilustrado (EOI) by Joseph Gumilla as a layered textual and cartographic artifact central to the production of colonial knowledge in the Orinoco River basin. Moving beyond surface narratives of evangelization and exploration, it interrogates the sombras and silencios implanted in the Jesuit chronicle. Through an intradisciplinary approach combining literary analysis, archival research, and visual studies, the study reveals how EOI helped construct imperial visions of space, race, and resource extraction in eighteenth-century Spanish America. The dissertation is structured around six chapters. Chapter One outlines a theoretical framework. Chapter Two provides a longue durée historical context, …


Social Media Listening Study To Understand The Journey And Unmet Needs Of Patients Living With Post-Stroke Spasticity, Stefano Carda, Jörg Wissel, Damon Hoad, Gerard E Francisco, Monica Verduzco-Gutierrez, Daniela Gallardo, Matteo Vacchelli, Jorge Jacinto Dec 2025

Social Media Listening Study To Understand The Journey And Unmet Needs Of Patients Living With Post-Stroke Spasticity, Stefano Carda, Jörg Wissel, Damon Hoad, Gerard E Francisco, Monica Verduzco-Gutierrez, Daniela Gallardo, Matteo Vacchelli, Jorge Jacinto

Faculty, Staff and Student Publications

Purpose: Stroke survivors may develop spasticity (post-stroke spasticity [PSS]) that can challenge activity and participation. Recognising the needs and expectations of people with PSS is crucial for enhancing care. This study is the first to employ social media listening to explore the experiences, unmet needs, and quality of life (QoL) of people with PSS.

Materials and methods: A subset of 417 patient-centric PSS-related posts published on major social media platforms was identified for analysis from 31 600 retrieved.

Results: Posts mainly discussed patient journey (centred around treatment options and management techniques), the impact of PSS on QoL, and patient interactions …


Early Identification For Spasticity Patient Referral Needs: An Inter-Rater Reliability Study Of The Post-Stroke Spasticity Referral Tool, Jorg Wissel, Atul Patel, Ganesh Bavikatte, Xiao Li, Sophie L Musson, Elizabeth Torres, Nabilah Alibhai, Tiziana Musacchio, Gerard E Francisco Dec 2025

Early Identification For Spasticity Patient Referral Needs: An Inter-Rater Reliability Study Of The Post-Stroke Spasticity Referral Tool, Jorg Wissel, Atul Patel, Ganesh Bavikatte, Xiao Li, Sophie L Musson, Elizabeth Torres, Nabilah Alibhai, Tiziana Musacchio, Gerard E Francisco

Faculty, Staff and Student Publications

Background: The post-stroke spasticity (PSS) Referral Tool was developed to assist health care professionals in the early identification of patient referral needs. An inter-rater reliability (IRR) study using videos of patients with different stages of or without predictors of PSS was performed to validate its utility in clinical practice.

Research design and methods: This prospective study had 3 parts: patient video production (Part A); expert panel classification of patient videos into PSS Referral Tool categories (Part B; Urgent Referral [UR; red], Routine Referral [RR; yellow], Periodic Monitoring [PM; green]), and an IRR analysis from global clinician raters (Part C). IRR …


Acculturation, Values, And Acculturative Stress For Autistic Latino Emerging Adults And Spanish-Speaking Parents Participating In The ¡Iniciando! La Adultez Program, Antonio F Pagán, Miriam Ortiz, Erin Bernal, Katherine A Loveland, Ana Esparza, Cecilia Montiel-Nava, Ron Acierno Dec 2025

Acculturation, Values, And Acculturative Stress For Autistic Latino Emerging Adults And Spanish-Speaking Parents Participating In The ¡Iniciando! La Adultez Program, Antonio F Pagán, Miriam Ortiz, Erin Bernal, Katherine A Loveland, Ana Esparza, Cecilia Montiel-Nava, Ron Acierno

Faculty, Staff and Student Publications

Latino families with emerging adults diagnosed with Autism Spectrum Disorder (ASD) face unique challenges during the transition to adulthood, influenced by cultural values, acculturation, and systemic barriers. Acculturation and acculturative stress are particularly relevant in this population, as they navigate cultural adaptation while maintaining traditional values like familismo (family) and respeto (respect). These dynamics are further complicated by disparities in access to resources and culturally responsive interventions. This study explores the interplay of cultural values, acculturation, and acculturative stress among Latino emerging adults with ASD and their Spanish-speaking parents participating in a culturally adapted and translated intervention. Using a cross-sectional …


A Prognostic Classification System For Extent Of Resection In Idh-Mutant Grade 2 Glioma: An International, Multicentre, Retrospective Cohort Study With External Validation By The Rano Resect Group, Philipp Karschnia, Jacob S Young, Maarten M J Wijnenga, Tommaso Sciortino, Nico Teske, Alba Corell, Arthur Wagner, Gilbert Youssef, Yae Won Park, Levin Häni, Stephanie T Jünger, Antonio Dono, Felix Ehret, Eduardo E Mendoza Mireles, Nicolas Neidert, Francesco Bruno, Chad A Tuchek, Thijs Van Der Vaart, Marco Rossi, Marco Conti Nibali, Lorenzo Gay, Alfred Gramelt, Nitin Tandon, Sung Soo Ahn, Jong Hee Chang, Michael Weller, Arnaud J P E Vincent, Roland Goldbrunner, Daniel P Cahill, Raymond Y Huang, Andreas Raabe, Bernhard Meyer, Juergen Beck, Annette M Molinaro, Susan M Chang, Michael A Vogelbaum, Roberta Rudà, Einar O Vik-Mo, Jorg Dietrich, Yoshua Esquenazi, Stefan J Grau, Patrick Y Wen, Asgeir S Jakola, Oliver Schnell, Lorenzo Bello, Martin J Van Den Bent, Shawn Hervey-Jumper, Mitchel S Berger, Joerg-Christian Tonn Dec 2025

A Prognostic Classification System For Extent Of Resection In Idh-Mutant Grade 2 Glioma: An International, Multicentre, Retrospective Cohort Study With External Validation By The Rano Resect Group, Philipp Karschnia, Jacob S Young, Maarten M J Wijnenga, Tommaso Sciortino, Nico Teske, Alba Corell, Arthur Wagner, Gilbert Youssef, Yae Won Park, Levin Häni, Stephanie T Jünger, Antonio Dono, Felix Ehret, Eduardo E Mendoza Mireles, Nicolas Neidert, Francesco Bruno, Chad A Tuchek, Thijs Van Der Vaart, Marco Rossi, Marco Conti Nibali, Lorenzo Gay, Alfred Gramelt, Nitin Tandon, Sung Soo Ahn, Jong Hee Chang, Michael Weller, Arnaud J P E Vincent, Roland Goldbrunner, Daniel P Cahill, Raymond Y Huang, Andreas Raabe, Bernhard Meyer, Juergen Beck, Annette M Molinaro, Susan M Chang, Michael A Vogelbaum, Roberta Rudà, Einar O Vik-Mo, Jorg Dietrich, Yoshua Esquenazi, Stefan J Grau, Patrick Y Wen, Asgeir S Jakola, Oliver Schnell, Lorenzo Bello, Martin J Van Den Bent, Shawn Hervey-Jumper, Mitchel S Berger, Joerg-Christian Tonn

Faculty, Staff and Student Publications

Background: The efficacy of resection in IDH-mutant grade 2 gliomas remain controversial since terminology for the extent of resection has been inconsistently applied across studies. We aimed to establish a standardised classification for the extent of resection and assess the association between supramaximal resection and survival across molecular subtypes.

Methods: In this international, multicentre, retrospective study, patients aged 18 years and older with newly diagnosed grade 2 IDH-mutant glioma were identified from institutional databases across 16 centres in the USA, Europe, and Asia between between Sept 1, 1993, and May 10, 2024. We used Cox proportional hazard regressions to analyse …


Short-Term Preeclampsia Prediction: Cutoff Variations For Sflt-1/Plgf In U.S. Patients With Or Without Hypertensive Disorders, Yaxin Li, Kristen Cagino, Jim Yee, Caroline Andy, Dajana Borova, Ayush Shah, Isla Racine, Tracy B Grossman, Zhen Zhao Dec 2025

Short-Term Preeclampsia Prediction: Cutoff Variations For Sflt-1/Plgf In U.S. Patients With Or Without Hypertensive Disorders, Yaxin Li, Kristen Cagino, Jim Yee, Caroline Andy, Dajana Borova, Ayush Shah, Isla Racine, Tracy B Grossman, Zhen Zhao

Faculty, Staff and Student Publications

Background: Preeclampsia (PE) is a complex disorder with significant maternal and fetal risks. The soluble fms-like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) ratio shows promise as a diagnostic tool, but its adoption in the U.S. remains limited due to the lack of accessible testing platforms, U.S.-based studies, and evidence-based implementation guidelines.

Patients/materials and methods: We conducted a cohort study to evaluate the sFlt-1/PlGF ratio for predicting PE within two weeks among pregnant individuals ≥18 years, ≥20 weeks gestation. Serum samples were obtained from routine prenatal visits or triage evaluations. sFlt-1/PlGF ratios were measured using Roche Elecsys assays, and …


Prone Percutaneous Jungbluth For Reduction Of Irreducible Posterior Pelvic Ring Injuries: A Technical Trick, Joseph M Radley, Jonathan A Copp, Daniel S Gloekler, Jonathan G Eastman Dec 2025

Prone Percutaneous Jungbluth For Reduction Of Irreducible Posterior Pelvic Ring Injuries: A Technical Trick, Joseph M Radley, Jonathan A Copp, Daniel S Gloekler, Jonathan G Eastman

Faculty, Staff and Student Publications

Unstable pelvic ring injuries represent a challenge due to the complex anatomy. Further, surgical access to the pelvic ring is altered by patient positioning in the supine versus prone position. Certain injury patterns present with the posterior pelvis in a fixed displaced position. These injuries can be exceedingly challenging to reduce from a supine position. In the prone position, these injuries can be reduced more directly with an open approach, but this is associated with wound healing complications. The technical trick herein demonstrated a successful technique utilizing a large Jungbluth clamp percutaneously applied to the posterior superior iliac spines with …


Assessment Of Postoperative Range Of Motion In Pediatric Patients Undergoing Surgical Reduction And Fixation Of Lateral Condyle Fractures, Gabrielle Rogie, Timothy Borden, Lindsay Crawford, Surya Mundluru, Brennan Roper, Rohini Mahajan Vanodia, Shiraz Younas Dec 2025

Assessment Of Postoperative Range Of Motion In Pediatric Patients Undergoing Surgical Reduction And Fixation Of Lateral Condyle Fractures, Gabrielle Rogie, Timothy Borden, Lindsay Crawford, Surya Mundluru, Brennan Roper, Rohini Mahajan Vanodia, Shiraz Younas

Faculty, Staff and Student Publications

Purpose: The objective of this study was to evaluate the outcomes of various methods of fixation for pediatric lateral condyle fractures. The null hypothesis was that there would be no difference between the three treatment groups and time of return to the full range of motion.

Method: There were three fixation groups-Algemeinshaft fur osteosynthesegragen (AO) cannulated screws (n = 11), buried Steinmann pins (n = 13), and unburied Steinmann pins (n = 36). Variables evaluated were time to return to full range of motion of the elbow, whether therapy was required, average number of follow-up visits, fracture …


Whipple Disease Initial Presentation As Supraclavicular Lymphadenopathy In A Patient With Rheumatoid Arthritis: A Diagnostic Challenge, Sara E Amin, Swati Gite, Audrey Wanger, Violeta Chavez, Jacob Armstrong, Beenu Thakral, Patricia Navarro, Jennifer Makhoul, Amer Wahed, Navneet Narula, Karan Saluja Dec 2025

Whipple Disease Initial Presentation As Supraclavicular Lymphadenopathy In A Patient With Rheumatoid Arthritis: A Diagnostic Challenge, Sara E Amin, Swati Gite, Audrey Wanger, Violeta Chavez, Jacob Armstrong, Beenu Thakral, Patricia Navarro, Jennifer Makhoul, Amer Wahed, Navneet Narula, Karan Saluja

Faculty, Staff and Student Publications

Whipple disease is a rare systemic disease caused by Tropheryma whipplei. It can present with a wide range of nonspecific symptoms that might overlap with underlying medical conditions, posing a diagnostic challenge. We present a 61-year-old man with a past medical history of rheumatoid arthritis and chronic inflammatory demyelinating polyneuropathy, who presented with persistent leukocytosis and supraclavicular lymphadenopathy. A positron emission tomography scan revealed hypermetabolic activity in the supraclavicular, abdominal, and pelvic lymph nodes along with a myocardial hypermetabolic lesion, concerning a lymphoproliferative disorder versus sarcoidosis. A supraclavicular lymph node excisional biopsy revealed complete architectural effacement by a diffuse foamy …


Navigating Health Literacy: Comparison Of Assessment Tools In A Surgical Safety-Net Population, Mokunfayo O Fajemisin, Stephanie Martinez Ugarte, Gabrielle E Hatton, Jackson G Burns, Lillian S Kao, Krislynn M Mueck Dec 2025

Navigating Health Literacy: Comparison Of Assessment Tools In A Surgical Safety-Net Population, Mokunfayo O Fajemisin, Stephanie Martinez Ugarte, Gabrielle E Hatton, Jackson G Burns, Lillian S Kao, Krislynn M Mueck

Faculty, Staff and Student Publications

Health literacy as measured by three validated assessment tools.


Refractory Hypoxemia In An Asymptomatic 6-Year-Old: It Is Not Always The Heart, Aymen Mirza, Bibek Bista, Vidhya Annavajjhala, Chinyere O'Connor Dec 2025

Refractory Hypoxemia In An Asymptomatic 6-Year-Old: It Is Not Always The Heart, Aymen Mirza, Bibek Bista, Vidhya Annavajjhala, Chinyere O'Connor

Faculty, Staff and Student Publications

No abstract provided.


Alk5 Inhibitor Impact On Bleomycin-Induced Systemic Sclerosis Mouse Model Via Multifunctional Optical Coherence Tomography, Pavel V Nikitin, Harshdeep S Chawla, Jessica Gutierrez, Geethangili Madamanchi, Manmohan Singh, Salavat R Aglyamov, Minghua Wu, Jerry Alonso, Matthew Fronheiser, Juliana Coculo, Shuyan Du, Shervin Assassi, Kirill V Larin Dec 2025

Alk5 Inhibitor Impact On Bleomycin-Induced Systemic Sclerosis Mouse Model Via Multifunctional Optical Coherence Tomography, Pavel V Nikitin, Harshdeep S Chawla, Jessica Gutierrez, Geethangili Madamanchi, Manmohan Singh, Salavat R Aglyamov, Minghua Wu, Jerry Alonso, Matthew Fronheiser, Juliana Coculo, Shuyan Du, Shervin Assassi, Kirill V Larin

Faculty, Staff and Student Publications

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by fibrosis, vascular dysfunction, and immune dysregulation, leading to significant morbidity and mortality. Noninvasive imaging techniques are critical for monitoring disease progression and evaluating therapeutic interventions. This study investigates the technical feasibility of multifunctional optical coherence tomography (OCT)-based methods for longitudinal assessment of skin thickness, stiffness, and microvasculature in a murine SSc model as a translational, noninvasive, and quantitative method to study disease progression and treatment response. Our findings demonstrate significant structural, biomechanical, and vascular changes in the skin's stiffness, indicative of fibrosis, a hallmark of SSc. The application of SB …


Peripheral Blood Gene Expression Profiling And Prognostic Significance For The Course Of Interstitial Lung Disease In Patients With Systemic Sclerosis, Shervin Assassi, Christopher P Denton, Matthias Zwick, Ramona Schmid, Carina Ittrich, Tobias Litzenburger, Sudha Visvanathan Dec 2025

Peripheral Blood Gene Expression Profiling And Prognostic Significance For The Course Of Interstitial Lung Disease In Patients With Systemic Sclerosis, Shervin Assassi, Christopher P Denton, Matthias Zwick, Ramona Schmid, Carina Ittrich, Tobias Litzenburger, Sudha Visvanathan

Faculty, Staff and Student Publications

Objective: We used data from the placebo arm of the Safety and Efficacy of Nintedanib in Systemic Sclerosis (SENSCIS) trial to determine the prognostic/predictive significance of peripheral blood cell (PBC) transcript modules for the course of forced vital capacity (FVC) in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD) with and without mycophenolate mofetil (MMF) treatment.

Methods: Patients had SSc-ILD with first non-Raynaud symptom within 7 years. MMF treatment was permitted if taken at a stable dose for ≥6 months. PBC RNA samples were taken at baseline. Global RNA sequencing was performed, followed by a modular analysis using 62 curated …