Digital Commons Network^™

The Effect Of Prednisolone Ingestion And Acute Exercise On Lipocalin-2 And Its Variants In Young Men: A Pilot Randomised Crossover Study, Carlie Bauer, Rhiannon K. Patten, Qiyang Sun, Haoyun Li, Daniels Konja, Mary Woessner, Xuzhu Lin, Andrew Garnham, David L. Hare, Peter R. Ebeling, Marc Sim, Joshua R. Lewis, Yu Wang, Lewan Parker, Itamar Levinger

Research outputs 2022 to 2026

Lipocalin-2 (LCN2) has three main variants; polyaminated (hLCN2) and non-polyaminated (C87A and R81E). The polyaminated form is proposed to positively influence energy control, whereas the non-polyaminated forms negatively impact energy control in mice. Glucocorticoids negatively affect glucose regulation and exercise has a positive effect. We hypothesise that glucocorticoids will suppress, while exercise will increase hLCN2, and decrease C87A and R81E, which will be associated with improved insulin sensitivity. In a randomised crossover design, nine young healthy men (aged 27.8 ± 4.9 years; BMI 24.4 ± 2.4 kg/m2) completed 30 min of high-intensity aerobic exercise (90–95% heart rate reserve) after glucocorticoid …

Alzheimer’S Disease Biological Pet Staging Using Plasma P217+Tau, Azadeh Feizpour, Vincent Doré, Natasha Krishnadas, Pierrick Bourgeat, James D. Doecke, Ziad S. Saad, Gallen Triana-Baltzer, Simon M. Laws, Rosita Shishegar, Kun Huang, Christopher Fowler, Larry Ward, Colin Masters, Jurgen Fripp, Hartmuth Kolb, Victor Villemagne, Christopher Rowe

Research outputs 2022 to 2026

Background: Plasma phospho-tau biomarkers, such as p217+tau, excel at identifying Alzheimer’s disease (AD) neuropathology. However, their ability to substitute for tau PET to identify AD biological stage is unclear. Methods: Participants included 248 cognitively unimpaired (CU) and 227 cognitively impaired (CI) individuals, with Janssen plasma p217+tau Simoa® assay, 18F-NAV4694 Aβ-PET (A) and 18F-MK6240 tau-PET (T) data. Biological PET stages were defined according to the Revised Criteria for Diagnosis and Staging of Alzheimer’s Disease (2024): Initial (A + T-), Early (A + TMTL +), Intermediate (A + TMOD +), and Advanced (A + THIGH +). The threshold for A+ was 25 …

Cutting Through The Fog: Recognising Brain Fog As A Significant Public Health Concern, Darren Haywood, Susan L. Rossell, Nicolas H. Hart

Research outputs 2022 to 2026

Brain fog is a highly common condition that can have significant impacts on quality of life and functioning. Most people will experience a condition, illness, or infection that might result in the development of brain fog. We provide a call to action to minimise the impacts of brain fog.

Health Outcomes Of Sarcopenia: A Consensus Report By The Outcome Working Group Of The Global Leadership Initiative In Sarcopenia (Glis), Charlotte Beaudart, Julian Alcazar, Ivan Aprahamian, John A. Batsis, Yosuke Yamada, Carla M. Prado, Jean Yves Reginster, Dolores Sanchez-Rodriguez, Wee Shiong Lim, Marc Sim, Stephan Von Haehling, Jean Woo, Gustavo Duque

Research outputs 2022 to 2026

The Global Leadership Initiative in Sarcopenia (GLIS) aims to standardize the definition and diagnostic criteria for sarcopenia into one unifying, common classification. Among other actions to achieve this objective, the GLIS has organized three different working groups (WGs), with the WG on outcomes of sarcopenia focusing on reporting its health outcomes to be measured in clinical practice once a diagnosis has been established. This includes sarcopenia definitions that better predict health outcomes, the preferred tools for measuring these outcomes, and the cutoffs defining normal and abnormal values. The present article synthesizes discussions and conclusions from this WG, composed of 13 …

Photocatalytic Performance Of N-Doped Ti3o5 Nano-Catalyst For Phenolic Compounds Removal From Industrial Wastewaters, Mehdi Narimani, Maryam Gonbadi, Mahsa Navabi, Fatemeh Khezri-Shooshtari, Amin Ale Ebrahim, Mohammad Mahdi Zerafat

Research outputs 2022 to 2026

This study is focused on the synthesis and evaluation of TiO2 and N-doped Ti3O5 for the photocatalytic degradation of phenol as a noxious substance commonly present in the industrial process effluents with harmful effects on human and the environment. The research addresses the critical environmental challenge posed by phenol-contaminated effluents from petrochemical industries. Leveraging Response Surface Methodology with Box-Behnken design, 17 experiments were conducted to analyze the impact of independent variables such as photo-catalyst dosage, pH, and irradiation time on degradation efficiency. Notably, the average crystallite sizes were determined as 20 nm for TiO2 and 58.3 nm for N-doped Ti3O5. …

Summarizing Attributable Factors And Evaluating Risk Of Bias Of Mendelian Randomization Studies For Alzheimer’S Dementia And Cognitive Status: A Systematic Review And Meta-Analysis, Xiaoni Meng, Xiaochun Li, Meiling Cao, Jing Dong, Haotian Wang, Weijie Cao, Di Liu, Youxin Wang

Research outputs 2022 to 2026

Background: No effective treatment is available to delay or reverse the onset and progression of Alzheimer’s dementia (AD). Mild cognitive impairment, a clinical state between normal aging and AD, may offer the proper window for AD intervention and treatment. This systematic review aimed to summarize evidence from Mendelian randomization (MR) studies exploring factors attributable to AD and related cognitive status and to assess its credibility. Methods: We searched PubMed, Embase, MEDLINE, and the Cochrane Library to identify MR studies investigating the associations between any factor and AD and related cognitive status. The risk of bias in MR studies was evaluated …

Performance Study Of A Woody Downdraft Gasifier: Numerical Investigation And Experimental Validation, Md Sanowar Hossain, Showmitro Bhowmik, Mujahidul Islam Riad, Md Golam Kibria, Barun K. Das, Sanjay Paul

Research outputs 2022 to 2026

Biomass gasification is an established and widely utilized renewable energy system. The research work aims to develop and construct a downdraft gasifier to investigate gasifier performance. The gasifier’s performance and cold gas efficiency were calculated for three volumetric airflow rates: 7.16 m3/h, 5.97 m3/h, and 4.78 m3/h. The efficiency was found maximum of 69.6% for an airflow rate of 7.16 m3/h. The oxidation zone and neck region of the gasifier reactor had the maximum recorded temperatures of 845 °C and 823 °C for Swietenia macrophylla (SM) and Mangifera indica (MI), respectively. A two-dimensional computational fluid dynamics (CFD) model for a …

The Supreme Court Of India's Use Of Inherent Power Under Article 142 Of The Constitution: An Empirical Study, M. P. Ram Mohan, Sriram Prasad, Vijay V. Venkitesh, Sai Muralidhar, Jacob P Alex

National Law School of India Review

The Constitution of India under Article 142 grants the Supreme Court of India broad inherent powers to do complete justice. The contours of these inherent powers and what it means to achieve complete justice were left to the Supreme Court to determine on its own. In this paper, we empirically examine all the Supreme Court cases from its inception in 1950 till 2023 which use the term “Article 142” or “complete justice.” We found 1579 cases, which were then hand-coded for many variables such as the nature of the case, where the case was appealed from, the temporal distribution, the …

Data Center Composite Load Model Parameters’ Tuning, Mohammed Sleiman, Amirreza Sahami, Oluwatimilehin Adeosun, Nathaniel Rice, Katelyn Vance

Electrical and Computer Engineering Faculty Research & Creative Works

The vast expansion of data center campuses has created concentrated and highly dynamic electrical loads that challenge traditional transmission system planning and protection studies. This paper presents a novel approach to model the load of data centers and validate their dynamic performance in a composite-load-model (CMLD) framework.

The data center has three major modules: a static element representing the static devices and busway impedance; an electronic-based element constituting power converters such as rectifiers and inverters, associated power supplies, and a motor-based element encompassing the induction nature of chillers, fans and pumps. Each module represented equivalent algebraic and differential equations depicting …

Language Learner Literature: A Mixed Methods Study, Esmeralda Mora

Dissertations

This dissertation, Language Learner Literature: A Mixed Methods Study, by Esmeralda Mora, Ed.D., of National Louis University, specializing in Curriculum, Advocacy, and Policy, investigated the impact of shifting a Midwest high school world language department from a traditional, grammar-focused model to a proficiency-based approach centered on Language Learner Literature (LLL). Employing a Modified Explanatory Sequential Mixed Methods Design, the study first analyzed longitudinal AAPPL proficiency scores from 1,134 high school students (2020–2025) using T-tests and Multiple Linear Regressions to establish measurable outcomes (the "what"). This quantitative phase demonstrated significant and consistent gains in expressive skills (Writing and Speaking) post-LLL implementation, …

Institutional Isomorphism, Top Management Commitment, And Environmental Disclosure In Tanzania’S Construction Sector, Aulelius Lema, Siasa Issa Mzenzi

Business Management Review

This study examined the influence of institutional isomorphism on environmental disclosure (ED) in Tanzania’s construction sector and the mediating role of top management commitment (TMC). A cross-sectional design was employed, with data collected from 314 construction firms. Environmental disclosure was measured using content analysis of financial reports, and Structural Equation Modelling using the Maximum Likelihood Estimation (MLE) method was used to estimate the structural model. The findings reveal that coercive, normative, and mimetic pressures significantly impact ED. The result also indicates that TMC significantly affects ED and mediates mimetic pressure’s effect, but does not mediate coercive or normative pressures. Similarly, …

Bone Void Filler Materials For Augmentation In Comminuted Fractures: A Comprehensive Review, S. Sina Mohammadi, Sunjeev S. Phull, B. Sonny Bal, Mark R. Towler

Chemical and Biochemical Engineering Faculty Research & Creative Works

Comminuted fractures, characterized by multiple bone fragments, present significant challenges in orthopedic surgery. Effective treatment often requires augmentation techniques to enhance fixation stability and promote bone regeneration. This review explores the application of bone void filler materials, including autografts, allografts, polymethyl methacrylate (PMMA), and synthetic bone substitutes such as calcium phosphate ceramics and bioactive glass, in managing comminuted fractures. Autografts are the gold standard due to their superior osteogenic potential but are limited by donor site morbidity and availability. Allografts mitigate these issues but face concerns regarding immunogenicity and reduced biological activity. PMMA, widely used for structural augmentation, provides immediate …

Local Hydrodynamics And Phase Distribution In Large-Scale Trickle Bed Reactors Using Multi-Detector Γ-Ray Densitometry, Sebastián Uribe, Ahmed Jasim, Saba A. Gheni, Nora Selem, Nouhaila Filali, Tiberiu M. Leib, Sourav Sengupta, Muthanna H. Al-Dahhan

Chemical and Biochemical Engineering Faculty Research & Creative Works

This study presents a new approach of using gamma ray computed tomography (CT) in a form of arc multi-detector γ-Ray Densitometry (Arc MD-GRD) Technique where it measures the line averaged holdups of the phases which are projected on the diameter of the column to obtain their diameter profiles. This technique then was used to investigate the diameter profiles of the phases' holdups in a 12-inch diameter trickle bed reactor (TBR) using sulfur hexafluoride (SF6) as the gas phase to represent to a certain extent the industrial higher density of the used gas phase due to either the type of the …

Time-Resolved 3d Momentum Spectroscopy In Continuous Wave Atomic Photoionization Experiments, K. L. Romans, B. P. Acharya, A. H.N.C.De Silva, K. Foster, O. Russ, Daniel Fischer

Physics Faculty Research & Creative Works

An experimental continuous-wave (cw) pump-probe scheme is demonstrated by investigating the population and photoionization dynamics of an atomic system. In particular, 6Li atoms are initially prepared in optically pumped 22S1/2 and 22P3/2 states before being excited via multi-photon absorption from a tunable femtosecond laser. The subsequent cascade back to the ground state is analyzed by ionizing the atoms in the field of a cw optical dipole trap laser. Conventional spectroscopic methods, such as standard cold-target recoil ion momentum spectroscopy or velocity map imaging, cannot provide simultaneous momentum and time-resolved information on an event-by-event basis for the system investigated here. The …

The Hand, Bob De Smith

Pro Rege

No abstract provided.

Slave Laborer Harvesting Sugar Cane, Pam Adams

Pro Rege

No abstract provided.

Antigone - Written By Sophocles, Adapted By Matt Minnicino, Laurel A. Koerner

Pro Rege

No abstract provided.

Unlocking The Potential Of Copper Sulfide Tailings As A Secondary Source For Tellurium And Precious Metals: A Comprehensive Characterization Study, Fardis Nakhaei, Lana Alagha, Gary Wyss

Mining Engineering Faculty Research & Creative Works

This study investigated historical copper sulfide tailings as an unconventional source of tellurium (Te), gold (Au), and silver (Ag). Advanced analytical studies were conducted to determine the geochemical and mineralogical properties of the tailing samples. The results showed that tetradymite (Bi2Te2S) was the predominant Te-bearing mineral, while hessite (Ag2Te) was a minor Te carrier, both notably occurring within fine-grained (< 8 μm) inclusions in pyrite. Gold was present as native Au, electrum (Au-Ag), and within complex silver tellurides hosted primarily in chalcopyrite and pyrite. Froth flotation studies showed that the 180 to 38 μm size range was the optimum feed size that yielded recoveries of 59 %, 37 %, and 27 % for Te, Au, and Ag, respectively. These findings suggested that froth flotation is a feasible method for concentrating Te-Au-Ag-bearing phases. Given the strong association between Te, Au, Ag, and Cu, the co-extraction of these metals should significantly enhance the economic viability of tailings' processing.

Tuning A Magnetic Energy Scale With Pressure And Field In Ute2, Hyunsoo Kim, I. Lin Liu, Wen Chen Lin, Yun Suk Eo, Sheng Ran, Nicholas P. Butch, Johnpierre Paglione

Physics Faculty Research & Creative Works

When a fragile ordered state is suppressed to zero temperature, a quantum phase transition occurs, which is often marked by the appearance of unconventional superconductivity. While the quantum critical point can be hidden, the influence of the quantum criticality extends to fairly high temperatures, manifesting non-Fermi liquid behavior in a wide range of the field-temperature-pressure phase space. Here, we report the tuning of a magnetic energy scale in the heavy-fermion superconductor UTe₂, previously identified with a peak in the c-axis electrical transport temperature dependence, using applied hydrostatic pressures and a-axis-oriented magnetic fields as complementary (and opposing) tuning parameters: …

Gry W Praktyce Zarządzania, Michał Mijal

Monografie/Monographs

Monografia podejmuje tematykę rosnącego zastosowania gier w zarządzaniu organizacjami. Autor szczegółowo klasyfikuje różne rodzaje gier, wskazując na ich zastosowanie w obszarach, takich jak rekrutacja, szkolenia, negocjacje i integracja zespołów, co sprawia, że praca jest praktyczna i dostarcza konkretnych przykładów, które mogą być użyte w codziennej praktyce menedżerskiej.

Games in Management Practice

The monograph addresses the growing use of games in organisational management. The author provides a detailed classification of different types of games, pointing to their application in areas such as recruitment, training, negotiations and team building, which makes the work practical and provides specific examples that can be used …

Uwarunkowania Zarządzania Siecią Bankomatów W Polsce – Analiza Rentowności, Arkadiusz Manikowski, Rafał Zbyrowski

Monografie/Monographs

Monografia poświęcona jest kompleksowej analizie funkcjonowania, kosztów i rentowności sieci bankomatów w Polsce, z uwzględnieniem uwarunkowań technologicznych, społecznych, przestrzennych i ekonomicznych. Autorzy prezentują w niej swoje wnikliwe badania obecnego stanu rynku oraz argumenty na rzecz modyfikacji niektórych jego parametrów.

Conditions for Managing an ATM Network in Poland – Profitability Analysis

This monograph presents a comprehensive analysis of the functioning, costs, and profitability of ATM networks in Poland, considering technological, social, spatial, and economic conditions. The authors present their insightful research on the current state of the market and arguments for modifying some of its parameters.

Finanse Cyfrowe: Tesserakt, Jakub Górka

Monografie/Monographs

Monografia przybliża sposób, w jaki technologie cyfrowe (m.in. sztuczna inteligencja, big data, blockchain, chmura obliczeniowa) oddziałują na usługi finansowe oraz wspierają rozwój innowacyjnych modeli biznesowych podmiotów świadczących usługi finansowe, oddziałują na struktury rynkowe czy transformują rynki finansowe oraz jakie generują konsekwencje społeczno-ekonomiczne.

Digital Finance: Tesseract

The monograph presents how digital technologies (i.e. artificial intelligence, big data, blockchain, cloud computing) affect financial services and support the development of innovative business models of financial service providers, influence market structures, transform financial markets, and generate socio-economic consequences.

Salinity Adaption And Toxicity Of Harmful Algal Blooms In Three Bays Of Great Salt Lake (Usa), W. A. Wurtsbaugh, Malin Olofsson, Gregory L. Boyer, Amy Marcarelli

Michigan Tech Publications

Cyanobacterial blooms can be harmful to animals and humans exposed to their toxins; however, their environmental drivers and boundaries still need to be elucidated. Salinity has been demonstrated to be an important driver of community composition that sets boundaries of species migration and survival. The filamentous cyanobacteria Nodularia spumigena forms dense blooms in estuaries around the world, produces the hepatotoxin nodularin, and has been thought to not survive or fix nitrogen (N) in high salinities. From 2005–2009 we studied three bays of Great Salt Lake (USA), two of which are estuaries with salinities ranging from 0 to >90 g L …

Investigating The Correlation And Synergy Of Artificial Intelligence Techniques, Construction Technologies, And Their Key Benefits, Fareed Salih, Islam H. El-Adaway

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Despite its reputation as one of the least digitized sectors, the construction industry increasingly adopts artificial intelligence (AI) and construction technologies. However, previous research has not adequately explored the benefits of AI techniques and construction technologies nor the correlations between them. This study aims to fill this knowledge gap. To this end, the authors used a multistep research methodology. First, a systematic literature review of studies published between 1985 and 2022 was conducted to identify AI techniques and construction technologies. Second, content and frequency analysis were performed to determine the benefits associated with AI and technology adoption. Finally, a survey …

Executive Compensation In A New Era: Pouring Old Wine Into New Bottles?, Florence Shu-Blankson

University of Dayton Law Review

The Author’s interest in executive compensation was sparked by the Delaware Court of Chancery’s decision to rescind the largest executive compensation package in U.S. history, awarded to Elon Musk by Tesla.1 Executive compensation has long been a contentious issue, and despite ongoing debates, efforts to regulate it effectively remain elusive. The process by which executive compensation committees and boards of directors determine these awards—along with their independence, the influence of controlling or dominant stockholders, and the transparency of decision-making— raises important questions about whether meaningful change is occurring or if the system remains fundamentally the same, merely repackaged as “old …

Effect Of Digital Noise Reduction Processing On Subcortical Speech Encoding And Relationship To Behavioral Outcomes, Subong Kim, Mary Schroeder, Hari M. Bharadwaj

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Perceptual benefits from digital noise reduction (NR) vary among individuals with different noise tolerance and sensitivity to distortions introduced in NR-processed speech; however, the physiological bases of the variance are understudied. Here, we developed objective measures of speech encoding in the ascending pathway as candidate measures of individual noise tolerance and sensitivity to NR-processed speech using the brainstem responses to speech syllable /da/. The speech-evoked brainstem response was found to be sensitive to the addition of noise and NR processing. The NR effects on the consonant and vowel portion of the responses were robustly quantified using response-to-response correlation metrics and …

Actual Uses Versus Paper Owners: The Ontario Court Of Appeal’S Decision In Kosicki V Toronto (City) In Context, Sarah E. Hamill

UBC Law Review

No abstract provided.

What Is The Standard Of Review For (Mixed) Constitutional Questions?, Anthony Sangiuliano, Mark Friedman

UBC Law Review

No abstract provided.

Essays On The Economics Of Farmland Valuation And Investment In U.S. Agriculture, Colson Tester

Graduate Theses and Dissertations

This dissertation presents three empirical essays that collectively advance the understanding of farmland valuation in key U.S. agricultural regions, emphasizing the critical advantages of comprehensive, transaction-based data over traditional survey methods. Farmland represents a significant portion of agricultural wealth, and its accurate valuation is crucial for farmers, investors, and policymakers, influencing everything from credit access to investment strategies. Historically, research has often relied on subjective survey data, which can suffer from biases, inaccuracies, and insufficient granularity. This dissertation addresses these limitations by leveraging extensive datasets of arm’s-length farmland transactions, offering a more precise and market-driven perspective on land values. The …

Analyzing Santa Clara University’S Food Procurement, Grace Falci, Isabelle Pink

Sustainable Food Systems Fellowship

As Food Systems Fellows (January - December 2025), we evaluated the environmental and social impacts of Santa Clara University’s food procurement system in partnership with the Center for Sustainability and SCU Auxiliary Services. Using the Real Food Challenge framework, we assessed SCU Dining Services’ progress toward sustainability commitments outlined in Leading Through Laudato Si’, including expanding sustainable purchasing, increasing plant-based spending, and sourcing ethically produced food. Analysis showed that 19.27% of food purchases in February and October 2024 met Real Food criteria. This is below prior-year Real Food percentages and the university’s 25% by 2025 goal. To accelerate progress, we …