Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Social and Behavioral Sciences (658264)
- Arts and Humanities (572945)
- Law (543430)
- Education (382353)
- Medicine and Health Sciences (325192)
-
- Physical Sciences and Mathematics (292575)
- Life Sciences (256271)
- Engineering (196357)
- History (181440)
- Business (149081)
- Higher Education (142751)
- Anthropology (115952)
- Religion (109898)
- Archaeological Anthropology (96468)
- Communication (89129)
- Sociology (86476)
- Library and Information Science (80029)
- United States History (77510)
- Medical Specialties (76856)
- Psychology (73605)
- Computer Sciences (63017)
- Public Affairs, Public Policy and Public Administration (62485)
- Earth Sciences (59351)
- Creative Writing (57942)
- Public Health (55614)
- Environmental Sciences (52395)
- English Language and Literature (47517)
- Economics (46863)
- Educational Administration and Supervision (46483)
- Music (45945)
- Institution
-
- University of South Florida (163042)
- University of New Mexico (139310)
- University of Nebraska - Lincoln (114006)
- Kenyon College (112919)
- University of Montana (98448)
-
- University of Mississippi (94608)
- University of New Hampshire (79660)
- Brigham Young University (72194)
- Georgia Southern University (61523)
- Eastern Illinois University (57889)
- Utah State University (57349)
- Mississippi State University (54520)
- Western Michigan University (52952)
- University of Kentucky (52308)
- Murray State University (50490)
- Purdue University (50072)
- University of Colorado Law School (47452)
- Louisiana State University (45136)
- Brigham Young University Law School (43717)
- University of Dayton (43233)
- Western Kentucky University (43085)
- Villanova University Charles Widger School of Law (42717)
- California Polytechnic State University, San Luis Obispo (42492)
- University of Central Florida (41628)
- Chulalongkorn University (37598)
- San Jose State University (36975)
- University of Northern Iowa (36015)
- University of Alabama at Birmingham (35953)
- Yale University (33842)
- Missouri University of Science and Technology (33676)
- Keyword
-
- Newspaper (47505)
- Latin America (31532)
- Press release; media release; press statement; news media information (30839)
- Spanish (30833)
- History (30082)
-
- University of New Mexico (29735)
- UNM (29638)
- LADB (29608)
- LAII (29608)
- Latin American and Iberian Institute (29608)
- Humans (29462)
- Education (28969)
- United States (21365)
- Student newspaper (19995)
- Newsletter (19707)
- EIU (19628)
- Georgia Southern University (18903)
- Newspapers (18264)
- Deaf culture (17102)
- Hearing impaired (17091)
- Pastoral care of people with disabilities (17060)
- Church work with the deaf -- Catholic Church (17052)
- Deaf -- Periodicals (17043)
- Athletics (16850)
- Marriage (16182)
- Poetry (15536)
- Students (15120)
- Higher education (14580)
- COVID-19 (14397)
- Female (14248)
- Publication Year
-
- 2026 (103181)
- 2025 (156460)
- 2024 (192792)
- 2023 (163016)
- 2022 (167875)
-
- 2021 (195846)
- 2020 (169236)
- 2019 (165296)
- 2018 (169978)
- 2017 (160808)
- 2016 (159444)
- 2015 (146249)
- 2014 (135654)
- 2013 (129983)
- 2012 (124624)
- 2011 (108195)
- 2010 (103561)
- 2009 (95666)
- 2008 (92735)
- 2007 (79196)
- 2006 (74520)
- 2005 (70127)
- 2004 (71235)
- 2003 (58626)
- 2002 (64483)
- 2001 (55062)
- 2000 (58461)
- 1996 (62302)
- 1992 (52971)
- 1990 (53642)
- Publication
-
- Four Valleys Archive (90475)
- Theses and Dissertations (74034)
- Faculty Publications (45677)
- Electronic Theses and Dissertations (35897)
- University of Montana News Releases, 1928, 1956-present (30910)
-
- Faculty Scholarship (25311)
- Dissertations (23679)
- The Auk (22791)
- Documents (21832)
- Theses (21690)
- Articles (20021)
- Browse All News (19555)
- Walden Dissertations and Doctoral Studies (19539)
- Masters Theses (18625)
- Master's Theses (18423)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (15281)
- Session Laws 1951-2000 (15051)
- NotiSur (13785)
- Faculty, Staff and Student Publications (13696)
- Hillsborough County Marriage Records (13681)
- University of Mississippi News (13497)
- Obituaries (13320)
- The Murray Ledger & Times (13003)
- Sheet Music Collection (12976)
- Michigan Law Review (12806)
- University of Montana Course Syllabi (12469)
- Honors Theses (12170)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (11863)
- Condor (11821)
- Defensive Publications Series (11767)
- Publication Type
Articles 111091 - 111120 of 5154651
Full-Text Articles in Entire DC Network
リアホナプロジェクト関連資料の利用法ガイド, Yoshihiko Ariizumi
リアホナプロジェクト関連資料の利用法ガイド, Yoshihiko Ariizumi
Spiritual Proficiency
啓示を力に変える:リアホナ抽出プロジェクト
「ウィッツ心理学(みたまと共に考え行動する心理学)」の土台を築くため、約3か月で400時間以上を費やし、4,000以上の日本語版『リアホナ』記事を徹底分析しました。この集中的な「リアホナプロジェクト」は、信仰に関する知識を、即座に活用できる実践的ツールへと変貌させました。
主な成果(デジタル宝庫):
-
350ページ超の核心データ: 記事から抽出されたインサイトをまとめた現象学的研究データ。
-
37の「実践原則&行動プラン」: AIを活用し、膨大なデータから導き出された5つの原則と具体的行動のセット。
-
37の聖餐会トーク原稿: 抽出された原則を、7分間の説得力あるスピーチ原稿に再構築。
-
霊的成長測定ツール: 個人の成長を多角的に測るための12の指標と10段階評価スケール。
-
飛躍と変革の秘蔵ツール: 努力を要するものの、力強い霊的成長をもたらすための追加資料。
このプロジェクトの全資料は、BYU ScholarsArchiveにて公開されています。あなたの信仰生活に確実な成果と継続的な啓示をもたらすための、このデジタル宝庫をぜひご活用ください。
Guide To Utilizing Liahona Project Related Materials, Yoshihiko Ariizumi
Guide To Utilizing Liahona Project Related Materials, Yoshihiko Ariizumi
Spiritual Proficiency
💡 Transforming Revelation into Power: The Liahona Extraction Project Guide
To establish the foundation of "Witts Psychology" (a psychology of thinking and acting with the Spirit), over 400 hours were spent analyzing 4,000+ Japanese Liahona articles in approximately three months. This intensive "Liahona Project" transformed knowledge about faith into immediately usable, practical tools.
Key Deliverables (Digital Repository):
-
Core Phenomenological Data: Over 350 pages of research data compiling extracted insights.
-
37 "Practical Principles & Action Plans": Five core principles and specific action sets derived from the data using AI.
-
37 Sacrament Meeting Talk Scripts: Principles restructured into compelling, 7-minute speeches.
-
Spiritual …
Self-Connection As A Mediator Between Exercise And Well-Being, Lauren Esmay
Self-Connection As A Mediator Between Exercise And Well-Being, Lauren Esmay
Walden Dissertations and Doctoral Studies
Scientists and health professionals have established the connection among physical activity and overall wellbeing. In more recent years, scholars have also researched the correlation among increased self-connection with increased overall well-being. Nevertheless, insignificant data has been gathered to investigate the impact of predictor variables upon the connection between exercise and wellbeing. This research study examined the mediating effect of self-connection among the relationship between exercise and wellbeing. The current study’s purpose was to gain better insights on how self-connection predicts a person’s physical activity, contributing to comprehensive insights how exercise habits may predict a person’s wellbeing by using a cross-sectional …
Educator Experiences With Implementing Every Student Succeeds Act Equity Mandates For Students With Autism, Jameelah S. Lewis
Educator Experiences With Implementing Every Student Succeeds Act Equity Mandates For Students With Autism, Jameelah S. Lewis
Walden Dissertations and Doctoral Studies
Educating students with autism spectrum disorder (ASD) in under resourced schools remains a persistent equity concern in the United States. This study addressed a gap in the existing research, as prior studies have examined special education policy and school-level implementation challenges, but few have explored the experiences of general education teachers implementing inclusion in low-socioeconomic public schools. The purpose of this generic qualitative study was to explore the barriers general education teachers encounter in providing equitable education and their recommendations for improving inclusion. The study was guided by Ingram and Schneider’s (1993) social construction theory, which explains how marginalized groups …
Small Business Owners’ Effective Strategies For Retaining Childcare Workers In Private Daycare Centers, Velma Williams Sanders
Small Business Owners’ Effective Strategies For Retaining Childcare Workers In Private Daycare Centers, Velma Williams Sanders
Walden Dissertations and Doctoral Studies
Ineffective retention strategies can lead to employee turnover. Private childcare business owners who struggle to improve employee retention may find their business confronting attrition as a result. Grounded in job embeddedness theory, the purpose of this qualitative pragmatic inquiry research project was to identify and explore effective retention strategies used by private childcare business owners to reduce high employee turnover rates. The participants were eight private childcare business owners who had implemented retention strategies. Data were collected through semistructured interviews, public websites, and public documents. Through thematic analysis, five themes were identified: (a) providing competitive rewards and family support; (b) …
Examining Job Demands And Resource Factors Impacting Job Satisfaction Amongst School Social Workers, Charmagne Williams
Examining Job Demands And Resource Factors Impacting Job Satisfaction Amongst School Social Workers, Charmagne Williams
Walden Dissertations and Doctoral Studies
The purpose of this quantitative study was to investigate the relationship between job demands and resources and job satisfaction among school social workers in North Carolina. School social workers are vital members of the school ecosystem, supporting the development and well-being of students, families, and communities. Grounded in the Job Demands-Resources (JD-R) theoretical framework, the impact of years of experience, caseload size, role ambiguity, burnout, and job autonomy on job satisfaction among school social workers was examined. The current study included 92 school social workers from twelve counties in the Sandhills and Research Triangle regions of North Carolina who completed …
Factors Affecting School Readiness And Level Of Distraction Among Black Children During Virtual Learning In The United States, Imani Barnes
Factors Affecting School Readiness And Level Of Distraction Among Black Children During Virtual Learning In The United States, Imani Barnes
Walden Dissertations and Doctoral Studies
The COVID-19 pandemic necessitated an shift to mandatory virtual learning (VL) for kindergarten through grade 12 students, disrupting educational systems globally and exposing systemic inequities. Although researchers had explored health and education disparities separately, they had not adequately examined the intersection of child health, specifically body mass index (BMI) and health-affected ability, with school readiness and level of distraction in VL environments. The purpose of this quantitative, cross-sectional study was to examine associations between BMI, health affected ability, school readiness, and distraction levels among U.S. Black children engaged in VL in the 2020 school year, controlling for gender, age, and …
Brain–Computer Interface Integration In Mental Health: Clinician Perspectives On Diagnostic Efficacy And Ethical Implications, Serena D. Sanders
Brain–Computer Interface Integration In Mental Health: Clinician Perspectives On Diagnostic Efficacy And Ethical Implications, Serena D. Sanders
Walden Dissertations and Doctoral Studies
This study explored the integration of brain–computer interface (BCI) technology into mental health care, focusing on clinicians' perceptions, ethical concerns, and the practical challenges associated with its adoption. As technological advancements in healthcare continue to reshape clinical practices, understanding how emerging technologies like BCI can be incorporated into therapeutic settings is essential. The purpose of this research was to examine clinician perspectives on the potential benefits of and barriers to BCI and to explore the ethical implications of its use in therapy. Guided by the technology acceptance model and the ethical decision-making framework, this qualitative study utilized semi structured interviews …
Tuning Switch Performance For Single Molecule Electronics, Elaina I. Grogg
Tuning Switch Performance For Single Molecule Electronics, Elaina I. Grogg
Longwood Senior Theses
In the field of single molecule electronics, chemical principles can be used to design molecules that are incorporated into metal-molecule-metal electronic junctions. Computational chemistry has been used to investigate changes in the performance of a single molecule switch. Changes in the on/off ratio of photoswitches due to the addition of electron-donating and electron-withdrawing substituents were observed. In many cases, the electrodes and electrode-molecule coupling have a more pronounced effect on the performance of the junction than other modifications within the molecule at the core of the junction. Chemical modifications on the molecular switch are used to demonstrate the ability to …
Quality Improvement (Qi) Project Aimed At Reducing 30-Day Hospital Readmissions For Patients With Congestive Heart Failure (Chf) Through Checklist Implementation, Gary Gutierrez
Seton Hall University Dissertations and Theses (ETDs)
Abstract
Congestive Heart Failure (CHF) remains a leading cause of preventable 30-day hospital readmissions,
especially in outpatient and transitional care settings. This quality improvement (QI) initiative was
launched within a private internal medicine practice in Essex County, New Jersey, to address this issue
by implementing a standardized CHF management checklist. The checklist focused on four key
components: (a) comprehensive medication reconciliation, (b) tailored patient education, (c) timely
follow-up appointments, and (d) improved interdisciplinary communication. By integrating evidence-
based practices into a structured workflow, the QI project aimed to improve care coordination,
empower patients to manage their condition, and reduce preventable …
Effective Digital Marketing Strategies For Small Businesses, Shannon Springob
Effective Digital Marketing Strategies For Small Businesses, Shannon Springob
Walden Dissertations and Doctoral Studies
The inability of many small businesses to effectively use digital marketing is a critical challenge for small business owners. Small business owners who lack effective digital marketing strategies are at greater risk of facing failure. Grounded in the do-it-yourself (DIY) behavioral theory, this qualitative pragmatic inquiry was conducted to identify, analyze, and explore the effective strategies employed by small business owners in the development and implementation of effective digital marketing campaigns. The participants included six small business owners in the United States who have used DIY digital marketing strategies within their businesses. Data were collected using semistructured interviews. Thematic analysis …
From Trauma To Triumph: A Qualitative Content Analysis Of Posttraumatic Growth In Children’S Animated Films, Crystal Victoria Tasker
From Trauma To Triumph: A Qualitative Content Analysis Of Posttraumatic Growth In Children’S Animated Films, Crystal Victoria Tasker
Walden Dissertations and Doctoral Studies
Children’s animated films have often been analyzed for problematic depictions of gender and cultural stereotypes, but far less attention has been given to how these narratives may portray psychological adversity and transformation. This study addressed this gap by examining how posttraumatic growth (PTG) is symbolized through the narrative arcs of ten Disney films released between 2013 and 2023. The purpose of this research was to explore how these films illustrate themes of emotional transformation, utilizing a theoretical foundation based on Tedeschi and Calhoun’s PTG model, which emphasizes five domains of growth following adversity: appreciation of life, enhanced relationships, personal strength, …
Education In The Planetarium: A Practical Approach, Matthew Fyfe
Education In The Planetarium: A Practical Approach, Matthew Fyfe
Honors Projects
This project proposes live planetarium programming built within the 5E instructional model. It creates a practical application of this with lesson modules surrounding topics in observational astronomy. Specifically, there are investigations into instrumentation through CCD cameras and data collection and processing through spectroscopy and photometry with light curve folding with activities highlighting each. Each module is broken down into segments corresponding to the learning cycles of the 5E model, and as they are self contained in this way can be used piecemeal in different combinations.
Structural Basis Of Panx1 Permeation And Positive Modulation By Mefloquine, Yangyang Li, Zheng Ruan, Junuk Lee, Ian Orozco, Edward Zhou, Juan Du, Wei Lü
Structural Basis Of Panx1 Permeation And Positive Modulation By Mefloquine, Yangyang Li, Zheng Ruan, Junuk Lee, Ian Orozco, Edward Zhou, Juan Du, Wei Lü
Department of Biochemistry and Molecular Biology Faculty Papers
Purinergic signaling relies on ATP release through exocytosis and large-pore channels. Large-pore channels permeate both small anions like chloride and large signaling molecules like ATP, but how this broad cargo selectivity is structurally controlled remains elusive. Here we investigate PANX1, a prototypical large-pore channel, and uncover structural plasticity at the extracellular entrance formed by seven tryptophan (W74) residues. The W74 sidechains are flexible, sampling conformations that range from a constricted state permissive only to chloride to a dilated state compatible with ATP. These states are coupled to variable cation-π interactions between W74 and arginine 75 (R75), suggesting a mechanism for …
Endowment For Educational Excellence Tennessee State University Foundation, December 2025, Tennessee. Comptroller Of The Treasury.
Endowment For Educational Excellence Tennessee State University Foundation, December 2025, Tennessee. Comptroller Of The Treasury.
Financial and Compliance Audit Reports
No abstract provided.
Tennessee State University, December 2025, Tennessee. Comptroller Of The Treasury.
Tennessee State University, December 2025, Tennessee. Comptroller Of The Treasury.
Financial and Compliance Audit Reports
No abstract provided.
Structural Birth Defects And Leukemia Risk In Children With Down Syndrome, Ching-Ju Hsu, Jeremy M Schraw, Sonja A Rasmussen, Tiffany M Chambers, Tania A Desrosiers, Chad D Huff, Amanda E Janitz, Russell S Kirby, Eirini Nestoridi, Wendy N Nembhard, Jason L Salemi, Charles Shumate, Jean Paul Tanner, Mahsa M Yazdy, Michael E Scheurer, Karen R Rabin, Philip J Lupo
Structural Birth Defects And Leukemia Risk In Children With Down Syndrome, Ching-Ju Hsu, Jeremy M Schraw, Sonja A Rasmussen, Tiffany M Chambers, Tania A Desrosiers, Chad D Huff, Amanda E Janitz, Russell S Kirby, Eirini Nestoridi, Wendy N Nembhard, Jason L Salemi, Charles Shumate, Jean Paul Tanner, Mahsa M Yazdy, Michael E Scheurer, Karen R Rabin, Philip J Lupo
Faculty, Staff and Students Publications
Birth defects are associated with increased cancer risk in the general pediatric population, yet their impact on leukemia risk in children with Down syndrome (DS) remains uncertain. We assessed this using data from 26,660 children with DS in the Genetic Overlap Between Anomalies and Cancer in Kids Registry Linkage Study. Among them, 71.9% had at least one major birth defect, predominantly involving the cardiac (64.2%), musculoskeletal (21%), and gastrointestinal systems (6.8%). The cumulative incidence of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) was comparable in children with and without co-occurring defects. Adjusted hazard ratios (aHR) for ALL and …
Reflecting On Ai Use Through Syllabus Statement Development, Jason Blomquist
Reflecting On Ai Use Through Syllabus Statement Development, Jason Blomquist
Biennial Convention (CONV)
As artificial intelligence (AI) tools become increasingly prevalent in higher education, nursing faculty face the complex task of developing comprehensive course policies that address both the opportunities and challenges these technologies present. This presentation provides guidance for crafting effective AI policies via course syllabi through faculty reflection on course content, pedagogy, and enhancing active learning.
Faculty will learn a structured practice for developing AI syllabi statements that align with course objectives while preserving essential nursing competencies. The practice framework addresses five critical elements: clear policy articulation, pedagogical rationale, specific usage guidelines, transparency requirements, and integration within existing academic integrity policies. …
Integrating Ai Tools For Literature Searches: Implementation In An Evidence-Based Practice Course, Ryoko Kausler
Integrating Ai Tools For Literature Searches: Implementation In An Evidence-Based Practice Course, Ryoko Kausler
Biennial Convention (CONV)
This interactive session presents practical strategies for incorporating AI tools in undergraduate nursing research/evidence-based practice (EBP) education, specifically focusing on literature search processes. EBP is fundamental for safe and effective patient care, yet nurses often struggle with implementing EBP in their daily practice.1,2 Over 50% of nurses rely on Google searches or peer advice rather than scholarly databases, highlighting the critical need to strengthen research competencies beginning at the undergraduate level.3 Similar to practicing nurses, undergraduate nursing students struggle with foundational EBP skills, particularly in efficiently searching and critically analyzing research literature.4,5 It is essential to develop …
Recognition As A Strategy For Member Engagement, Brenda Owusu, Jacqueline Thomas
Recognition As A Strategy For Member Engagement, Brenda Owusu, Jacqueline Thomas
Biennial Convention (CONV)
Purpose: Member engagement, participation and commitment to professional organization is important to meet organization goals leading to its growth and development. Effective strategies are essential to promote involvement, increase retention, and enhance community among members (Frangieh et al., 2024). One practical approach is recognizing outstanding contributions at the section level within regional chapters. Such initiatives help cultivate a culture of appreciation, motivating members to stay actively involved and contribute further to the organization’s goal. Public acknowledgment of members’ efforts also fosters a sense of belonging and pride, which can lead to increased loyalty and commitment to the organization (Lansing et …
Celebration As A Strategy For Member Engagement, Karis Casseus, Karen Worthy
Celebration As A Strategy For Member Engagement, Karis Casseus, Karen Worthy
Biennial Convention (CONV)
Purpose: Engagement is the foundation for cultivating vibrant and sustainable professional organizations, and Sigma exemplifies this commitment through its robust focus on member involvement. Celebrating organizational events is a strategic mechanism to enhance connections, commemorate achievements, and solidify the shared values that unify members. (Eddy et al., 2021; Sweeney & Wiseman, 2023). Celebratory environments are consistently linked to heightened satisfaction and commitment, driving long-term organizational success (George & Massey, 2020; Reid, 2024). This presentation delves into the transformative impact of planned celebrations and intentional recognition, formal or informal, in fostering member engagement by nurturing a sense of belonging, elevating morale, …
Fostering Nursing Professional Identity Through A Comprehensive Teaching Strategy, Kathleen M. Williamson
Fostering Nursing Professional Identity Through A Comprehensive Teaching Strategy, Kathleen M. Williamson
Biennial Convention (CONV)
OBJECTIVES:
- Describe the significance of developing a strong professional identity in nursing.
- Explore methods for incorporating reflective practice as a teaching strategy to help nursing students internalize professional values.
- Integrate reflective practice to support the development of professional identity among students.
The development of a strong professional identity is crucial for nursing students as it shapes their values, behaviors, and attitudes towards patient care. This presentation will share a teaching strategy that was designed to incorporate the concept of professional identity in nursing. The strategy employed reflective practice to foster understanding of professional identity among nursing students.
This presentation will …
Using Well-Being, Professional Identity, And Civility Best Practices In A Nursing Academic Setting, Jennifer Louise Embree
Using Well-Being, Professional Identity, And Civility Best Practices In A Nursing Academic Setting, Jennifer Louise Embree
Biennial Convention (CONV)
OBJECTIVES:
- Discover perspectives of well-being in academics
- Describe methods for determining Professional Identity in Nursing
- Determine methodology to detect aspects of academic civil work environment
Identifying perspectives is critical to intervention implementation and strategy. Authors describe the Mini-Z General, the Healthy Work Environment Index, the Civility Work Index, and Professional Identity in Nursing (PIN) Survey to identify and measure well-being, PIN, a healthy work environment, and civility among faculty and staff.
Data demonstrated a stress and best practice intervention was need for well-being, PIN, and civility. Identifying well-being and envisioning the future programming state can guide change and support various …
Living The Balance Theory Of Wisdom With Leadership Values In Mind, Daniel J. Pesut
Living The Balance Theory Of Wisdom With Leadership Values In Mind, Daniel J. Pesut
Biennial Convention (CONV)
In creating the Balance Theory of Wisdom, Sternberg (1) defined wisdom as the application of intelligence, creativity, and knowledge to the common good by balancing and mediating the values of self (intrapersonal), others (interpersonal), and institutional (extra-personal) interests over the long and short terms in service of adapting, shaping, and selecting environments, that is, to represent, respect, reflect, and respond in shaping the future. The functional consequences of this definition suggest that wise people have exceptional insight into human development and life matters, look for deeper meaning, tolerate ambiguity, have compassion, are other- and purpose-focused, and recognize the limits of …
Caring Science As Embodied Wisdom: Balancing Intrapersonal, Interpersonal, And Extrapersonal Factors, Sara Horton-Deutsch
Caring Science As Embodied Wisdom: Balancing Intrapersonal, Interpersonal, And Extrapersonal Factors, Sara Horton-Deutsch
Biennial Convention (CONV)
The intersection of caring science and the balance theory of wisdom reveals profound connections between therapeutic practice and theoretical frameworks of human understanding. We examine how caring science inherently encompasses explicit knowledge—systematic, teachable aspects of healthcare—and tacit knowledge—intuitive, experience-based understanding practitioners develop over time. Exploring these knowledge domains with the lens of the balance theory of wisdom aligns caring science with the theory's core principles of balancing multiple interests, adapting to environmental contexts, and pursuing the common good (1).
Practicing through the lens of caring science implicitly aligns with wisdom-based decision-making by balancing intrapersonal (self), interpersonal (others), and extrapersonal (institutional) …
Trump-Appointed Judges Reverse Preliminary Injunction Against Military Trans Ban, Arthur S. Leonard
Trump-Appointed Judges Reverse Preliminary Injunction Against Military Trans Ban, Arthur S. Leonard
Other Publications
No abstract provided.
First-In-Child Phase I Trial Of P-Stat3 Inhibitor Wp1066 In Pediatric Brain Tumor Patients, Robert C Castellino, Hope L Mumme, Andrea T Franson, Bing Yu, M Hope Robinson, Kavita Dhodapkar, Dolly Aguilera, Matthew J Schniederjan, Rohali Keesari, Zhulin He, Manoj Bhasin, Waldemar Priebe, Amy B Heimberger, Tobey J Macdonald
First-In-Child Phase I Trial Of P-Stat3 Inhibitor Wp1066 In Pediatric Brain Tumor Patients, Robert C Castellino, Hope L Mumme, Andrea T Franson, Bing Yu, M Hope Robinson, Kavita Dhodapkar, Dolly Aguilera, Matthew J Schniederjan, Rohali Keesari, Zhulin He, Manoj Bhasin, Waldemar Priebe, Amy B Heimberger, Tobey J Macdonald
Faculty, Staff and Student Publications
Background: WP1066 is an orally bioavailable, small molecule inhibitor of activated p-STAT3 that has demonstrated preclinical efficacy in pediatric brain tumor models.
Methods: In a first-in-child, single-center, single-arm 3+3 design Phase I clinical trial, ten patients were treated with WP1066 twice daily, Monday-Wednesday-Friday, for 14 days of each 28-day cycle to determine the maximum tolerated dose (MTD)/maximum feasible dose (MFD) of WP1066. Compassionate use treatment with WP1066 in three pediatric patients with H3.3 G34R/V-mutant high-grade glioma (HGG) is also described.
Results: There was no significant toxicity and the MFD was determined to be 8 mg/kg. Treatment-related adverse events were Grade …
Role Of Cellular Stress Responses In Innate Immune Defense Against Acute Respiratory Infections, Amit Sharma
Role Of Cellular Stress Responses In Innate Immune Defense Against Acute Respiratory Infections, Amit Sharma
LSU Doctoral Dissertations
The endoplasmic reticulum (ER) stress sensor inositol-requiring enzyme 1α (IRE1α) is an important regulator of innate immune cells. However, its role in pulmonary innate host defenses remains poorly understood. This dissertation elucidates the dual, context-dependent role of IRE1α in host defense against methicillin-resistant Staphylococcus aureus (MRSA) pneumonia. We demonstrate IRE1α’s function as both a detrimental mediator of acute pathology and an essential facilitator of innate immune memory. Our work revealed that acute IRE1α activation during primary MRSA infection is detrimental. In lungs and alveolar macrophages (AMs), IRE1α is activated in response to MRSA infection. Consequently, IRE1α activation triggers a hyperinflammatory …
Biosynthesis, Characterization Of Curcumin-Capped Zno-Cuo And Chitosan-Curcumin-Capped Zno-Cuo Based Omaterial As Antibacterial Agent Of Escherichia Coli, Ahmad Fatoni, Afnita Fatmawati Umli, Reza Agung Sriwijaya, Hilma Hilma, Nurlisa Hidayati
Biosynthesis, Characterization Of Curcumin-Capped Zno-Cuo And Chitosan-Curcumin-Capped Zno-Cuo Based Omaterial As Antibacterial Agent Of Escherichia Coli, Ahmad Fatoni, Afnita Fatmawati Umli, Reza Agung Sriwijaya, Hilma Hilma, Nurlisa Hidayati
Chimica et Natura Acta
The biofabrication of the chitosan-curcumin-capped ZnO-CuO and curcumin-capped ZnO-CuO oparticles, as well as their ability to combat Escherichia coli bacteria, were the focus of this study. Fourier-Transform Infrared (FTIR) spectroscopy, X-ray diffraction (XRD), and Scanning Electron Microscopy (SEM) were used to examine the chitosan-curcumin-capped ZnO-CuO and curcumin-capped ZnO-CuO oparticles, respectively. Both were evaluated using the agar diffusion method as antibacterials against Escherichia coli. Results of analysis with FTIR, between 500 and 700 cm⁻¹, the functional group of Cu-O or Zn-O was seen at its highest point. The functional group of Cu-O and Zn-O in curcumin-capped ZnO-CuO was detected at wavenumber …
2025 December 11 - Tennessee Weekly Drought Summary, East Tennessee State University
2025 December 11 - Tennessee Weekly Drought Summary, East Tennessee State University
Tennessee Climate Office Weekly Drought Summaries
No abstract provided.