Digital Commons Network^™

Integrating Peer Specialists In Primary Care: Narrative Review With Illustrative Examples, And Pragmatic Recommendations To Support Implementation, Emily M. Johnson, Christina Shook, Kimberly Barrie, Kyle Possemato

The Journal of Integrated Primary Care

Behavioral health peer support specialists, peers, are health care system employees with lived experience of mental health or substance use concerns who are trained and hired to support others with behavioral health concerns in behavioral health clinics and medical settings. Peer-delivered services have a long history and research consistently demonstrates evidence of varied benefits for a wide range of patients. Peers are increasingly being hired to work within primary care settings to support the needs of primary care patients with behavioral health concerns and enhance the interdisciplinary nature of integrated primary care teams. However, integration of peers into this new …

Process For The Preparation Of Gadolinium-Based Contrast Agents And Its Intermediates, Msn Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan; Sagyam Rajeshwar Reddy; Velishala Praveen And Vadlakonda Srikanth.

Defensive Publications Series

The present application relates to a process for the preparation of 2,2',2''-(1,4,7,10-Tetraazacyclododecane-1,4,7-triyl)triacetic acid represented by the following structural formula-3.

Formula-3.

Present disclosure also describes a novel crystalline form of Calteridol calcium and its process for the preparation.

Constrained Response Generation For Conversational Generative Ai Agents, Łukasz Bieniasz-Krzywiec, Kyle Boone, Ryan Carl Yao Yu

Defensive Publications Series

The use of generative artificial intelligence (AI) agents in various applications can be affected by the underlying models exhibiting hallucinations and/or vulnerability to prompt injection attacks. In customer-facing applications, such as taking orders for quick service restaurants (QSR) or drive-through restaurants, model hallucinations can create a risk of brand damage and/or bad publicity. This disclosure describes techniques that constrain the output of generative AI agents using deterministic control to reduce off-topic or inappropriate responses in structured conversational contexts such as order-taking in a quick service restaurant. A deterministic control module includes a state machine whose states are the current context. …

Ai-Assisted Meeting Lifecycle Management For Enhanced Productivity, Anton Volkov, Lindsay Moore, Kimberly Ha, Dom Ekeledo, Juan Angustia, Felix Mejia, Sara Olson, Joy Barlow, Awaneesh Verma, Avery Fisher, Adam Karnas, Ravi Mruthyunjaya, Rabia Murtza, Kristin Moore, Kelly Dern, Yury Pinsky, Ryan Fedyk, Arvid Callas

Defensive Publications Series

Meeting productivity is often hindered by attendees being unprepared, a lack of clear objectives, and difficulty in tracking discussions and outcomes. This leads to inefficient use of time and a loss of valuable information, as post-meeting actions and decisions are frequently unclear or forgotten. The problem extends beyond video conferences to phone and in-person meetings, which often lack any formal support structure. This disclosure describes a system that uses artificial intelligence to manage the entire meeting lifecycle. The system provides pre-meeting briefings with contextual information, offers real-time in-meeting assistance for note-taking and agenda management, and generates post-meeting summaries with actionable …

Cross-Probe Virtual Element Synthesis For Ultrasound Imaging, Diane Manthey, Anonymous

Defensive Publications Series

This invention describes a system and method for synthesizing virtual ultrasound elements by combining physical elements from two separate probes

Adaptive Placement Of Augmented Reality User Interface Elements Using Reinforcement Learning, Dongeek Shin

Defensive Publications Series

Conventional augmented reality (AR) systems often struggle to accurately and contextually place user interface (UI) elements, leading to a non-immersive or intrusive user experience. This disclosure presents a method for personalized UI placement in AR through reinforcement learning. The technique utilizes an agent trained with deep reinforcement learning to determine the optimal position and orientation of virtual UI elements. Input features, including environmental depth maps, eye-tracking data, and application context, are processed to inform placement decisions. The agent learns from both implicit user interactions, like gaze aversion or physical interference, and explicit user corrections. This process allows the UI placement …

Cross-Device Eye-Tracking Calibration Via Reference Model Remapping, Mar Gonzalez Franco, Eric Jordan Gonzalez, Lucy Abramyan, Karan Ahuja, Prasanthi Gurumurthy, Khushman Jayantilal Patel

Defensive Publications Series

Eye-tracking calibration models are often specific to a particular device’s sensor geometry, requiring extensive data collection and retraining when camera or LED positions are altered in new hardware. This process is resource-intensive and hinders the portability of models across different devices. A method is disclosed for adapting a comprehensive eye-tracking model from a reference device to a new device with a different sensor layout. By collecting a minimal set of new calibration points on the target device, a transformation matrix is generated. This matrix remaps the existing reference model to the new geometry. The primary purpose of this technique is …

Visual Cue For Item Value Discrepancy In An Augmented Reality Environment, Nick Dugal

Defensive Publications Series

Wearable devices, such as augmented reality (AR) devices and smart glasses, lack an intuitive, non-disruptive mechanism for informing a user about suboptimal pricing for a viewed item. This disclosure describes a method for displaying a dynamic visual cue, such as a stylized line, proximate to an item’s displayed price. The properties of this cue, including color, thickness, or animation, can be modified to convey the magnitude of the value discrepancy. User interaction with the cue can reveal detailed comparison pricing sourced from various databases. This price-matching information can also be transferred to a secondary device. The primary purpose is to …

Automated Spatial Localization Of Iot Devices Via Visual Detection And Network-Initiated Feedback, Michael Christopher Yu

Defensive Publications Series

Manually registering the spatial positions of numerous Internet of Things (IoT) devices within an Extended Reality (XR) environment is a cumbersome process for users. This lack of automated spatial mapping limits the ability to perform context-aware interactions with these devices. The disclosed method addresses this by using an XR device’s vision and depth sensors to first detect a potential IoT device and estimate its 3D position. The XR device then sends a network-based request to candidate devices, instructing them to provide a confirmation signal, such as illuminating an LED. When the XR device’s camera detects this signal, the device's identity …

Design-Time Preview System For Blended User Interfaces On Transparent Displays, Adhithya Ramakumar, Louis Benedict Pullen-Freilich

Defensive Publications Series

Designing user interfaces for transparent additive displays presents a challenge in which graphical blend modes alter specified UI colors based on the real-world background, creating a mismatch between the design intent and the final user experience. This limitation forces a slow, iterative workflow of deploying to a physical device to verify visual appearance. A method is disclosed for generating an accurate design-time preview of such UIs directly within a development environment. The technique renders the complete UI to an offscreen buffer and then composites the UI against a representative background using a graphics layer with a specified blend mode. This …

Predicting User Interaction Intent For Adaptive Ui Highlighting In Extended Reality Environments, Tushar Chugh, Aditya Shrikant Mone, Karthik Kumara

Defensive Publications Series

In extended reality (XR) environments, persistent highlighting of user interface (UI) elements based on gaze can distract users during non-interactive tasks, such as reading. Conversely, a complete lack of highlighting can reduce interaction precision and increase the risk of accidentally activating critical controls. The disclosed technology is a method for adaptive gaze highlighting that dynamically controls the visibility of these visual cues. The method utilizes a model to analyze multimodal inputs, such as gaze patterns, gestural cues, and application context, to predict a user’s intent to interact. A necessity score is calculated based on the UI element’s characteristics and the …

Addressing Challenges In Accessing Secondary And Tertiary Healthcare Services For Migrants And Refugees In Egypt, Noura Seada, Nehal El-Bakhshawangy, Heba Semary, Fatma Alzahraa Hassan, Ahmed Hammad

Papers, Posters, and Presentations

The growing number of vulnerable migrants and refugees worldwide presents a significant challenge to host countries, particularly in terms of accessing healthcare services. Egypt hosts over 9 million migrants and refugees, with 1.5 million in a vulnerable situation. Despite the country’s efforts in providing adequate healthcare to these vulnerable groups, some challenges persist. This paper addresses the barriers that vulnerable migrants and refugees face when seeking secondary and tertiary healthcare services in Egypt, analyzing the legal, economic, social, and health system factors that contribute to this problem.

In 2018, the Egyptian government began an ambitious journey to reform its healthcare …

Development Of An Iot-Based Energy Theft Detection System For A Single-Phase Smart Meter, Ojo Julius Oladele, Funso Kehinde Ariyo, Samson Oladayo Ayanlade, Ayooluwa Peter Adeagbo, Ismail Adeniyi Adeleke

Al-Bahir

Electricity theft causes annual global losses exceeding $96 billion, severely impacting distribution networks. This paper presents a novel IoT-based system integrating current differential sensing, physical tamper detection, and edge-cloud analytics to detect energy theft in single-phase smart meters. The design employs three ACS712 current sensors to monitor Kirchhoff-compliant current flow at the grid pole, meter input, and load output, coupled with a PIR sensor for cabinet intrusion. A SIM800L GSM module enables real-time theft alerts and remote disconnection, while closed-loop control autonomously restores power after tamper resolution — a feature absent in prior GSM-only systems. An Android application provides geotagged …

Corrigendum To “Yi-Qi-Xuan-Fei Formula Ameliorate Chronic Obstructive Pulmonary Disease By Remodeling Lung And Intestinal Florase In Rat Models” [J Food Drug Anal 33(3) (2025) 252-276]

Journal of Food and Drug Analysis

No abstract provided.

2025 Acknowledgment Of Reviewers

Journal of Food and Drug Analysis

No abstract provided.

Economic Evaluation Of Ai-Assisted Technologies In Healthcare: A Systematic Review, Wen-Tung Wu, Yi-Wen Chao, Tsung-Kun Lin, Ching-Kuo Huang, Ping-Hsuan Hsieh

Journal of Food and Drug Analysis

Artificial intelligence (AI) technologies are increasingly integrated into healthcare, yet their economic value remains uncertain. Traditional economic evaluation methods may not adequately capture the unique features of AI, including dynamic model evolution, scalability, and broader societal impacts. This systematic review synthesized existing evidence on the cost-effectiveness of AI-based healthcare interventions and assessed the methodological rigor of published studies. A comprehensive search identified health economic evaluations of AI applications published between September 2019 and March 2025, following PRISMA and SWiM guidelines and registered in PROSPERO (CRD42025641230). Eligible studies were full economic evaluations comparing AI-based interventions with non-AI alternatives, and data were …

Combination Treatment Of Cordycepin And Radiation Induces Apoptosis Accompanied By Protective Autophagy In Tm3 Mouse Leydig Progenitor Cells, Yu-Yan Lan, Yi-Ping Lee, Wei-Ru Huang, Chun-Ying Yu, Lyh-Jyh Hao, Chun-Hung Lin, Bu-Miin Huang

Journal of Food and Drug Analysis

Leydig cells are anatomically located in the testicular interstitial tissue, and their main function is to produce and secrete testosterone and indirectly support spermatogenesis. We previously reported that the combination treatment of cordycepin and radiation can effectively induce Leydig tumor cell apoptosis through cell cycle arrest, caspase activation, endoplasmic reticulum (ER) stress, reactive oxygen species (ROS) accumulation, and DNA damage. However, there is still a lack of scientific evidence for the susceptibility of normal Leydig cells to the combination treatment. In the present study, mouse TM3 Leydig progenitor cells were used as a model to evaluate the effects and mechanisms …

Development Of An Untargeted Metabolomics Analytical Protocol For Fecal Samples By Liquid Chromatography–Mass Spectrometry, Tsai-Wei Ting, Chih-Ning Cheng, Chieh-Chang Chen, Ching-Hua Kuo

Journal of Food and Drug Analysis

Gut microbiota has recently gained attention for its role in regulating multiple host pathways and contributing to disease developments. Fecal metabolomics using liquid chromatography—mass spectrometry (LC—MS) offers a promising approach to study gut microbial metabolites; however, it remains technically challenging due to the complex, heterogeneous nature of fecal samples and the lack of standardized protocols. This study aimed to establish a robust and reproducible untargeted fecal metabolomics workflow. We systematically evaluated sample preparation parameters―including sample amount, extraction solvent, numbers of extraction, and sample-to-solvent ratio―and assessed method reproducibility. Additionally, we compared three LC—MS data acquisition workflows using 10 samples from inflammatory …

Dna Tetrahedron-Au Nps-Go For Enhanced Fluorescence Detection Of Serotonin, Zhang Yun, Wu Qiong, Gao Hui, Zhang Hua, Miao Xiang-Min

Journal of Food and Drug Analysis

Evidence had accumulated that serotonin (5-HT), a hormone and neurotransmitter, was not only involved in a variety of different physiological and central nervous system functions but also in the development and manifestation of psychiatric diseases. Here, DNA tetrahedron-Au NPs-GO for enhanced fluorescence sensor was designed for detecting serotonin. Au NPs-GO was used as a fluorescence quencher, while fluorophore-labeled DNA tetrahedron was used as a donor, resulting in fluorescence resonance energy transfer (FRET) from the fluorophore to Au NPs-GO (signal off). With the strong binding ability of aptamer to serotonin, S5 was released from Aptamer: S5 duplex, then reacted with the …

Carotenoids Identified From Slipper-Shaped Oyster Magallana Bilineata Powder Residue Exhibit Potent Biological Activities, Rhoda Mae C. Simora, Raymund B. Parcon, Andrea Roxanne J. Anas, Tatsufumi Okino

Journal of Food and Drug Analysis

Carotenoids are a diverse class of biologically active compounds that contribute significantly to human health, serving vital functions in nutrition and overall well-being. Magallana bilineata, a commercially important oyster species, yields a shelf-stable powder residue possessing bioactivities with unknown specific compounds. Carotenoids are key marine bioactive compounds, but their presence in oysters remains underexplored. The present study aimed to identify the bioactive compounds from oyster powder residue through mass spectrometry for optimum utilization and value creation as a biomedical resource. The study employed solvent extraction of oyster powder residue, followed by fractionation using octadecylsilyl (ODS) column chromatography, liquid chromatography-mass …

Selective Sodium-Glucose Cotransporter Two Inhibitor Empagliflozin Ameliorates Diabetic Cardiomyopathy By Activating The Ampk/Tfeb Signaling Pathway., Man-Chen Hsu, Ru-Wen Chang, Mu-Chun Wang, Chia-Hui Chen, Wen-Hua Chen, Tzong-Shyuan Lee, Chih-Hsien Wang

Journal of Food and Drug Analysis

The highly selective SGLT2 inhibitor (SGLT2i) is reported to have beneficial effects on diabetic cardiac hypertrophy; however, the molecular mechanisms underlying the cardioprotection of SGLT2i are not fully understood. In this study, we investigated the impact of the SGLT2 Inhibitor empagliflozin (EMPA) on diabetic hearts and its regulatory mechanisms in high-fat-diet (HFD)- and streptozotocin (STZ)-treated rats. Male rats orally administered HFD/STZ treatment for eight weeks, with or without EMPA (10 mg/kg), were used as our in vivo model. Hematoxylin and eosin (H&E) staining was used for histological examination. Western blot analysis and immunohistochemistry were used to analyze the expression of …

Targeting Chemical Carcinogenesis: Α-Pinene And D-Limonene As Chemopreventive Agents Against Nnk/ Tcdd- And Urethane-Induced Lung Tumorigenesis, Kuo-Ching Huang, Vui-Hyen Chew, Yu-Ying Chen, Huey-Jen Su, Hao-Ting Chang, Rong‑Jane Chen, Ying‑Jan Wang

Journal of Food and Drug Analysis

Lung cancer is the leading cause of cancer-related deaths worldwide, driven by carcinogens such as tobacco-derived nitrosamines, dioxins, and urethane. This study evaluated the chemopreventive effects of two monoterpenes, α-pinene and D-limonene, using NNK/TCDD- and urethane-induced lung tumor models and A549 lung cancer cells. Both compounds significantly reduce tumor number and size, with enhanced effects when combined. Mechanistic studies revealed suppression of PRC1, β-catenin, and c-Myc, alongside activation of p53, Bax, and caspase-3, indicating inhibition of the PRC1—Wnt/β-catenin pathway and induction of apoptosis. These findings suggest α-pinene and D-limonene as safe, promising agents for lung cancer chemoprevention.

Fish Oil Rich In Ω-3 Fatty Acid Alleviates Long-Term High Fructose Consumption-Induced Fatty Liver And Kidney Dysfunction In Rats, Shing-Hwa Liu, Ruoh-Wenn Hung, Ting-Yu Chang, Meng-Tsan Chiang

Journal of Food and Drug Analysis

Excessive fructose intake leads to fatty liver and kidney dysfunction, with associated inflammation and metabolic disturbances. This study evaluated the effects of fish oil rich in ω-3 fatty acid on these conditions in rats fed a high- fructose diet. Male Sprague Dawley rats were divided into three groups: normal diet, high-fructose (HF) diet, and high- fructose diet with 5% fish oil supplementation. The experiment lasted for 21 weeks. Fish oil supplementation significantly reduced blood levels of total cholesterol, triglycerides, and advanced glycation end products (AGEs) in HF-fed rat. It also improved liver function markers and kidney function indicators. Mechanistically, fish …

Effects Of Chamomile And L-Theanine Beverage On Menstrual Pain, Menstrual Symptoms, Mood, And Sleep Quality In Young Women Experiencing Primary Dysmenorrhea: A Randomized, Double-Blind, Placebo-Controlled Study, Ziqing Soh, Soo Cing Tan, Tak Hiong Wong, Seok Tyug Tan, Seok Shin Tan, Chin Xuan Tan

Journal of Food and Drug Analysis

Primary dysmenorrhea is one of the most common complaints among young women. This study aimed to evaluate the effects of chamomile and L-theanine beverage intake on menstrual symptoms, pain intensity, mood, and sleep quality in young adult females with primary dysmenorrhea, using a two-phase continuous study design. In the first phase, a cross-sectional study was conducted to assess the prevalence of primary dysmenorrhea. In the second phase, participants were randomly assigned to either the intervention group (n =15), which consumed chamomile and L- theanine beverage (CTT), or the control group (n =15), which consumed chamomile-flavored beverage (non-CTT). Beverages …

Cordycepin In Cancer Therapy: A Bibliometric Analysis And Review Of Mechanisms, Zhiwei Ouyang, Yufei Zhang, Jianghan Ning, Yayi Tu, Bin He

Journal of Food and Drug Analysis

Cordycepin (3’-deoxyadenosine), a major bioactive component derived from fungi of the genus Cordyceps, has garnered significant attention in recent years for its potent antitumor properties. Drawing on literature indexed in the Web of Science Core Collection from 2004 to 2025, this study employs bibliometric tools―specifically CiteSpace and VOSviewer―to systematically examine developmental trends, research hotspots, and emerging frontiers in the field of cordycepin-related cancer research. The analysis maps a shift in focus from early-stage pharmacological validation to more advanced investigations into molecular mechanisms, with particular emphasis on cell cycle regulation. Keyword burst analysis highlights bursts in terms such as “apoptosis,” “cell …

Distinguishing Avocado Oil Quality Based On Fatty Acid Profile Using Pca: A Review Of Influencing Factors And Research Gaps, David Fernando, Ali Ridho Arif Madja, Nur Azizah, Agustina Ari Murti Budi Hastuti, Abdul Rohman

Journal of Food and Drug Analysis

The quality of avocado oil is influenced by multiple factors, including cultivar, growing region, drying method, harvest season, fruit maturity, extraction technique, and storage conditions. This review aims to show how fatty acid profiles (FAP), combined with principal component analysis (PCA), can be used to characterize avocado oil based on various established factors. A total of 23 peer-reviewed articles were included, encompassing 143 data points. PCA was applied as an exploratory tool to reduce dimensionality and visualize patterns in the data. Among the evaluated variables, the fruit part emerged as the most influential determinant, allowing clear categorization of avocado oils …

Research And The Information Landscape, Libby Wheeles, Helena Marvin

Open Educational Resources Collection

This open textbook accompanies the University of Missouri-St. Louis class INTDSC 1010: Research and the Information Landscape. Intended for undergraduates new to academic research, the course covers practical search and evaluation skills as well as a basic introduction to the world of scholarly communication. In Fall 2025, the course’s learning objectives were:

1. Evaluate whether a source is appropriate for college-level research.
2. Navigate library search tools to find relevant results and improve research efficiency.
3. Analyze the goals and limitations of non-library tools in the research landscape.
4. Explain the basic history and current broad practices of scholarly communication.
5. Contribute to a small-scale …

Cv: Rachel Wells (Social Work), Rachel Wells

Social Work Department Faculty Curricula Vitae

No abstract provided.

Cv: Martha Jarmuz (Clinical Mental Health Counseling), Martha Jarmuz

Psychology Department Faculty Curricula Vitae

No abstract provided.

Cv: Keith Lavine (Industrial/Organizational Psychology), Keith Lavine

Psychology Department Faculty Curricula Vitae

No abstract provided.