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Clinical Complications And Management Strategies For Wolcott-Rallison Syndrome, Pavan K. Madasu, Durga Ashok Burande, Nivedhitha Ulaganathan, Thyageshwar Chandran

Journal of Pediatric Genetics

Wolcott-Rallison syndrome (WRS) is a rare genetic disorder, diagnosed with transient/permanent neo-natal insulin-dependent diabetes mellitus (IDDM). Infants are primarily diagnosed with the onset of diabetes mellitus followed by a propensity for skeletal dysplasia, liver dysfunction, pancreatic hypoplasia, renal dysfunction, mental retardation, seizures, stenosis, and glycosuria. Unfortunately, regardless of the symptoms or poor prognosis, most of the infants could not survive beyond two years, and those who survived do not live a quality life before death. However, despite these clinical complications, clinical intervention at a right time can contribute to prolonged life expectancy. The transplantation of vital organs (liver, pancreas and …

Handwritten Notes On Broadcast, Bob Schieffer

Bob Schieffer Vietnam War Collection

Notes on a segment of a radio broadcast from Fort Worth Star-Telegram.

Speech On Fort Worth Star-Telegram, Bob Schieffer

Bob Schieffer Vietnam War Collection

Speech addressing current war and situation in Vietnam.

Report On Vietnam, Bob Schieffer

Bob Schieffer Vietnam War Collection

Report about life in Vietnam and details about the war, and handwritten notes with report outline.

Handwritten Notes, Bob Schieffer

Bob Schieffer Vietnam War Collection

Random piece of paper with notes about military personnel and information.

Report From Fort Worth Star-Telegram

Bob Schieffer Vietnam War Collection

Article on the Fort Worth Star-telegram about Bob Schieffer.

Handwritten Notes, Bob Schieffer

Bob Schieffer Vietnam War Collection

Pieces of paper with a list of things and short statement about the Vietnam war.

Handwritten Notes, Bob Schieffer

Bob Schieffer Vietnam War Collection

A piece of paper with notes about military personnel and information.

Notes On Military Life, Bob Schieffer

Bob Schieffer Vietnam War Collection

Pieces of paper with notes on Vietnam and descriptions of military experiences.

Bob Schieffer Activities And Notes, Bob Schieffer

Bob Schieffer Vietnam War Collection

Notes about activities and military personnel written on the back of the report.

Letter From U.S. Forces, U.S. Seventh Fleet Information Office

Bob Schieffer Vietnam War Collection

Year end wrap up of navy activities in the air release #146-65, December 31st, 1965.

Notes On Military Personnel, Bob Schieffer

Bob Schieffer Vietnam War Collection

Random pieces of paper with names and information about military personnel.

Bob Schieffer Activities And Notes, Bob Schieffer

Bob Schieffer Vietnam War Collection

Random pieces of paper with diary entries about daily activities and information about military personnel.

Bob Schieffer Notebook, Bob Schieffer

Bob Schieffer Vietnam War Collection

A notebook with names and information about military personnel.

Bob Schieffer Notebook, Bob Schieffer

Bob Schieffer Vietnam War Collection

A notebook with names and information about military personnel.

A Proposed Secure Video Using Lightweight Chacha20 Based On Chaotic Map, Hadeel Mohammed Taher, Ali Makki Sagheer

Iraqi Journal for Computer Science and Mathematics

Multimedia content has become a necessary part of our daily lives in many domains, including medical imaging, surveillance, and entertainment. Among all multimedia categories, video is mainly critical because of its high content density and large size. For that, ensuring the security of video has become a necessity for transmission and storage. This paper proposed an enhancement to the Chacha algorithm integration with a hybrid chaotic map for generating keys to secure video. The main motivation for the selection ChaCha algorithm is that it is fast, simple, and appropriate for widespread applications, whereas the motivation for using chaos is to …

Diagnosis And Management Of New-Onset Central Diabetes Insipidus In Critically Ill Children Varies Between Pediatric Critical Care Medicine And Pediatric Endocrinology Clinicians, R. Brandon Hunter, Herodes Guzman, Jessica Winters, Katherine Lord, Matthew Kirschen, Vijay Srinivasan

Journal of Pediatric Intensive Care

Introduction: The diagnosis and management of central diabetes insipidus in critically ill children is not standardized. Our objective was to characterize differences between Pediatric Critical Care Medicine (PCCM) and Pediatric Endocrinology (PE) clinicians in diagnosis and management of new-onset CDI in the pediatric intensive care unit. We also sought to characterize knowledge gaps among general pediatrics (GP) residents. Materials and Methods: A scenario-based survey to assess patterns of diagnosis and management of new-onset CDI that was distributed to PCCM, PE and GP clinicians who work in a quaternary care urban children’s hospital. Results: Of 275 PCCM, PE and GP clinicians …

Characterization Of Pediatric Patients With Rheumatological Diseases Admitted To A Single Tertiary Health Hospital’S Pediatric Intensive Care Unit In Latin America, Valeria Erazo-Martínez, Ingrid Ruiz-Ordoñez, Carolina Álvarez, Laura Serrano, Cristian C. Aragón, Gabriel J. Tobón, Sandra Concha, Rubén Lasso, Lyna Ramírez

Journal of Pediatric Intensive Care

Objetives: Most autoimmune diseases (AIDs) during childhood debut with more severe and aggressive forms, with life-threatening conditions that increase the need for intensive care therapy. This study describes the clinical, laboratory, and health outcomes features of pediatric patients with AIDs admitted to the pediatric intensive care unit (PICU). Methods: This is a retrospective cross-sectional study that included the clinical records of all pediatric patients with AIDs admitted to the PICU during 2011 and 2020 in Cali, Colombia. Results: Two-hundred and twenty-five PICU admissions from 136 patients were evaluated. Median age was 13 (11-15) years, and the median disease duration was …

The Effect Of Aminophylline On Urine Output And Fluid Balance After A Single Dose In Children Admitted To The Pediatric Cardiac Intensive Care Unit, Rohit S. Loomba, Sruti Uppuluri, Priya Chandra, Faeeq Yousef, Vincent Dorsey, Juan S. Farias, Saul Flores, Enrique G. Villarreal

Journal of Pediatric Intensive Care

Introduction: The purpose of this retrospective study was to investigate the effects of a single dose of aminophylline on urine output and fluid balance in children admitted to the cardiac intensive care unit. Methods: A retrospective study was done to compare variables of interest before and 24 hours after aminophylline administration in children under the age of 18 years who were admitted to the cardiac intensive care unit at our institution from January 2011 onwards. Variables of interest included age, weight, aminophylline dose, concurrently administered diuretics, specific hemodynamic parameters, and blood urea nitrogen and creatinine levels. Variables such as urine …

Perspectives On Current Mechanical Ventilation Use And Training In Pediatric Critical Care Medicine Fellowship Programs In The United States Of America, Matthew P. Malone, Erin Bennett, O. Katherine Irby, Sanjiv Pasala, Ronald C. Sanders, Beverly J. Spray, Abdallah Dalabih

Journal of Pediatric Intensive Care

Objective: Mechanical ventilation (MV) is an integral part of the care of the critically ill child, and contemporary MV includes a myriad of sophisticated modalities that should be tailored to specific disease pathology and severity. This requires Pediatric Critical Care Medicine (PCCM) physicians to have comprehensive training and experience with various modes. We sought to assess and describe the current landscape of MV practices and training from PCCM fellowship programs. Methods: To describe current MV practices and training in PCCM fellowship programs and assess the different modes of MV to which trainees are exposed, a piloted survey was sent to …

Patient-Specific Factors Associated With Dexmedetomidine Dose Requirements In Critically Ill Children, Karryn R. Crisamore, Philip E. Empey, Jonathan H. Pelletier, Robert S.B. Clark, Christopher M. Horvat

Journal of Pediatric Intensive Care

Objective: To evaluate patient-specific factors associated with dexmedetomidine dose requirements during continuous infusion. Methods: A retrospective cross-sectional analysis of electronic health record-derived data spanning ten years for patients admitted with a primary respiratory diagnosis at a quaternary children’s hospital and who received a dexmedetomidine continuous infusion (N=346 patients) was conducted. Penalized regression was used to select demographic, clinical, and medication characteristics associated with median daily dexmedetomidine dose. Identified characteristics were included in multivariable linear regression models and sensitivity analyses. Results: Critically ill children had a median hourly dexmedetomidine dose of 0.5 mcg/kg/hr (range: 0.1 - 1.8), median daily dose of …

Beyond Vital Signs: Pediatric Sepsis Screening That Includes Organ Failure Assessment Detects Patients With Worse Outcomes, Jesseca A. Paulsen, Karen M. Wang, Isabella M. Masler, Jessica F. Hicks, Sherry N. Green, Jeremy M. Loberger

Journal of Pediatric Intensive Care

Objective: Pediatric sepsis screening is recommended. The 2005 Goldstein criteria, the basis of our institutional sepsis screening tool (ISST), correlates poorly with clinically diagnosed sepsis. The study objective was to retrospectively evaluate the ISST sensitivity compared to the Pediatric Sequential Organ Failure Assessment (pSOFA). Methods: Single-center retrospective cohort study. The primary outcome was pSOFA score and ISST sensitivity for severe sepsis. Secondary outcomes included clinical outcome measures. Results: In this severe sepsis cohort (N=491), pSOFA and ISST sensitivity were 57.6% and 61.1%, respectively. In regression analysis for a positive pSOFA, positive blood culture (OR 2.2, 95% CI 1.1-4.3, p=0.025), older …

Outcomes Of Pediatric Drowning In The Pediatric Intensive Care Unit, Rebecca K. Aures, Jennifer Rosenthal, Ashley Chandler, Toby Raybould, Michael R. Flaherty

Journal of Pediatric Intensive Care

Objective: Drowning remains a leading cause of death in children. Knowledge of outcomes of these patients who survive drowning but require critical care is lacking. We aim to study the current mortality rate, describe interventions and associated diagnoses, and examine factors related to risk of death in drowning victims admitted to the pediatric intensive care unit (PICU). Methods: Retrospective multicenter cohort study utilizing data from the Virtual Pediatric Systems Database in 143 PICUs between January 1, 2010 and December 31, 2019. Patients between 0-18 years old admitted to a PICU with a diagnosis of drowning were included. The primary outcome …

Early Oral Rehydration Therapy In Diabetic Ketoacidosis: A Randomized Controlled Study, Shourya Vijay Tej Kola, Shalu Gupta, Virendra Kumar

Journal of Pediatric Intensive Care

Objectives: We aimed to compare the efficacy of oral versus intravenous fluid therapy in correcting dehydration in diabetic ketoacidosis (DKA) when pH was ≥ 7.25 and Glasgow coma scale (GCS) score was ≥ 12. We also compared the time to resolution of DKA. Subjects: Children aged ≤ 18 years with DKA were included in the study. In our pilot study, 40 children were enrolled from June 2018 to April 2019, and divided into two groups after achieving pH ≥ 7.25 and GCS score ≥ 12. Materials and Methods: This was an open-label, parallel-arm, randomized control trial conducted in the pediatric …

Role Of Serum Ferritin And Prism-Iii In Predicting Mortality In Children With Acute Encephalitis Syndrome In Northern India, Nisha Toteja, Rohit Sasidharan, Sachin Kumar, Kamran Zaman, Vijay Kumar Singh, Vineet Jaiswal, Kanchan Srivastava, Harish Tiwari, Mahima Mittal

Journal of Pediatric Intensive Care

Objectives: The aim of this study was to evaluate the role of Serum Ferritin (SF) and PRISM-III (Paediatric Risk of Mortality) in predicting mortality in critically ill children aged six months to 15 years diagnosed with Acute Encephalitis Syndrome (AES) admitted to the Paediatric Intensive Care Unit (PICU). Methods: This prospective observational study was conducted in the PICU of a tertiary teaching hospital in Northern India between July 2018 and June 2019. The primary outcome was to determine the association of admission SF levels with mortality. Secondary outcomes included estimating the prevalence of hyperferritinemia and comparing SF with PRISM-III scores …

Clinical Profile Of Multisystem Inflammatory Syndrome In Children [Mis-C] Associated With Sars-Cov-2 Admitted To Pediatric Intensive Care Unit, Yashaswini K., A. V. Lalitha, Naresh Kanna Giri Subramanian, John Michael Raj A.

Journal of Pediatric Intensive Care

Objectives: Multisystem Inflammatory Syndrome in children (MIS-C) is a post SARS-CoV-2 immune dissonance seen in the pediatric population. The current study is an attempt to understand subtleties of diverse phenotypes, immunotherapeutics and short-term outcome parameters of MIS-C. Methodology: Children admitted to Pediatric intensive care unit [PICU] between 1 month – 18 years, satisfying MIS-C criteria were enrolled in this retrospective observational study. They were stratified into different phenotypes like shock, Kawasaki disease and non - specific phenotypes. Respiratory, vasoactive support and outcomes were analyzed using appropriate statistical methods. Results: Seventy-five children presented with MISC during the study period. The mean …

Taking Charge: Revisiting The Enforcement Of Inter-Creditor Agreements In Ibc-Driven Liquidations, Priyanshu Shrivastava, Hemang Mankar

National Law School Business Law Review

No abstract provided.

Trial Practice And Procedure, Joseph M. Colwell, Christopher B. Mcdaniel, John D. Flowers, Madi Mcmichael Moseley

Mercer Law Review

This Article addresses selected opinions and legislation of interest to the Georgia civil trial practitioner issued during the survey period of this publication.

An Exception To Prove The Rule: Rebutting The Presumption Of A Consistent And Definitive Construction, Miles C. Skedsvold

Mercer Law Review

Because the State of Georgia has had ten constitutions since declaring independence from Great Britain, the history of those prior constitutions has a lot to do with understanding the Constitution in force today. In particular, when a provision is carried forward from one constitution to the next without material change, the Supreme Court of Georgia’s decisions interpreting that provision under an earlier constitution can be a key piece of evidence for understanding its meaning in the later one.

The Supreme Court of Georgia calls this piece of the historical inquiry the presumption of a consistent and definitive construction: the provision …

Critical Engagement With Gpt In U.S. History: Full Integration In An Undergrad Setting, Matt Meador

Teaching Repository of AI-Infused Learning

This project integrates a custom-trained GPT model into undergrad U.S. History courses to support students in analyzing primary sources, evaluating historical perspectives, and bridging the gap into AI Literacy. Students use AI to generate draft responses, then critically review, annotate, and revise outputs, ensuring that human oversight fosters deeper historical thinking rather than passive acceptance of machine responses.