Digital Commons Network^™

Gender Representation In Automotive Safety: The Role Of Female Crash Test Dummies, Gökçe Hilal Yavuz, Emre Arabaci, Ajab Khan Kasi

Platform: A Journal of Engineering (PAJE)

Vehicle testing is conducted to evaluate safety, durability, environmental compliance, and performance. Various tests, such as crash, performance, durability, environmental impact, and chemical safety, are conducted to ensure that vehicles meet regulatory and quality standards. In crash testing, anthropomorphic test devices (ATDs), commonly referred to as dummies, are used to simulate the effects of collisions on the human body and to assess injury risks. These dummies differ in terms of gender representation and design; for example, the Hybrid III model represents an average male, EvaRID represents a female, and WorldSID is used for side-impact evaluations. Anatomical and biomechanical differences between …

A Hybrid Reliability Framework For Spare Part Optimisation Under Uncertainty Of Marine Vessel Systems, Ahmad Fauzi Sagap, Ainul Akmar Mokhtar

Platform: A Journal of Engineering (PAJE)

Effective spare part management relies heavily on accurate reliability assessment. However, in new or complex systems, historical failure data are often limited, making traditional probabilistic reliability models inadequate. This paper proposes a hybrid reliability framework that integrates conventional reliability theory with fuzzy logic to address both aleatory (random)and epistemic (lack of knowledge) uncertainties. The approach combines crisp failure rate estimation using exponential distributions with fuzzy reliability modelling using the triangular fuzzy number (TFN) methodology and fuzzy logic to support dynamic decision-making for a maintenance plan. The degree of membership functions is derived from the TFN and provides the operator with …

Computer Applications In Electrical Engineering: Recent Trends, Future Requirements, And An Educational Review, Hemant Mehar

Platform: A Journal of Engineering (PAJE)

The integration of programming languages into electrical engineering has become increasingly pivotal as the field evolves with technological advancements. This paper explores recent trends in the application of programming languages in electrical engineering, emphasising how they enhance design, simulation, and automation. The main focus is on the use of high-level programming languages for modelling and simulation, and on various algorithm-based ML approaches for optimisation. Additionally, the paper examines future requirements for programming skills in electrical engineering, highlighting the need for continuous adaptation to emerging technologies and interdisciplinary approaches. An educational review is provided to assess current curricula and suggest improvements, …

Cfd Modeling Of A 120 Kwth Chemical Looping Combustion System, Tabasat Ahmad, Fazl E Rabi, Muhammad Zaman, Atta Ullah

Platform: A Journal of Engineering (PAJE)

```python text = """Chemical looping combustion (CLC) has evolved as a promising technique for carbon capture. In view of the above, a computational fluid dynamics (CFD) study of the existing 120 kWth circulating fluidised bed (CFB) has been carried out. The fuel used in the existing reactor is CH4, and NiO supported by Al2O3 particles is employed as the oxygen carrier. Transient Two-dimensional CFD simulations have been conducted for the DCFB–CLC system. Eulerian –Eulerian method with heterogeneous reaction kinetics has been applied. The CFD simulation yielded results comparable to those obtained from the experimental data. The same approach was then …

Inflammatory Co-Regulation Of Voltage-Gated Sodium Channels And Na,K-Atpase In Metastatic Breast Cancer, Steven D. Scahill, Kelly Jean Sherman, Dennis Paul

School of Graduate Studies Faculty Publications

Sodium regulation is a potentially major driver of cancer metastasis. Voltage-gated sodium channels (VGSCs) and Na,K-ATPase are sodium transporters that are upregulated in many advanced carcinomas and are implicated as metastatic drivers. However, little is known about what drives this overexpression, how these proteins influence metastatic behavior, or whether these complementary sodium transporters are co-regulated in cancer. Using sodium transporter regulation in healthy neurons as a model, the present study demonstrated that the inflammatory mediator tumor necrosis factor alpha (TNFα) affects the expression of VGSCs and Na,K-ATPase in an in vitro model of metastatic breast cancer. Acute TNFα challenge increased …

Gut Microbiome Metagenomics In Clinical Practice: Bridging The Gap Between Research And Precision Medicine, Henok Ayalew Tegegne, Tor C Savidge

Faculty, Staff and Students Publications

Gut microbiome metagenomics is emerging as a cornerstone of precision medicine, offering exceptional opportunities for improved diagnostics, risk stratification, and therapeutic development. Advances in high-throughput sequencing have uncovered robust microbial signatures linked to infectious, inflammatory, metabolic, and neoplastic diseases. Clinical applications now include pathogen detection, antimicrobial resistance profiling, microbiota-based therapies, and enterotype-guided patient stratification. However, translation into routine care is hindered by significant barriers including methodological variability, limited functional annotation, lack of bioinformatics standardization, and underrepresentation of global populations. This review synthesizes current translational strategies, emphasizing the need for hypothesis-driven designs, multi-omic integration, longitudinal and multi-center cohorts, and mechanistic validation. …

Us Drug Policy Does Not Align With Experts' Rankings Of Drug Harms: A Multi-Criteria Decision Analysis, Michael Broman, Alan K. Davis, Stacey Armstrong, Adam Levin, Kaltum Ahmed, Gustavo A. Angarita, Brooke J. Arterberry, Cecilia Bergeria, Mitch Earleywine, Kathryn S. Gex, Tom Gregoire, Jamey J. Lister, David S. Mathai, Nicky J. Mehtani, Nathan Menke, Charles D. Nichols, Hillary Shaub, Alayna P. Tackett, Brandon Weiss, Nefize Yalin, Lawrence D. Phillips

School of Medicine Faculty Publications

Background United States drug policy is primarily based on the Controlled Substances Act of 1970 and largely contradicts scientific evidence about how to mitigate drugs' harms. Expert consensus on drug harms could inform policy that improves the health of people who use drugs while reducing negative societal impacts of drug use. Therefore, this study adapted and extended the relevant 2010 United Kingdom multi-criteria decision analysis, rating drug harms by criteria comprising health and social impacts to people who use drugs and their families, communities, and society.Methods Seventeen experts on drug use in the US, including three with lived experience of …

Us Drug Policy Does Not Align With Experts’ Rankings Of Drug Harms: A Multi-Criteria Decision Analysis, Michael Broman, Alan K Davis, Stacey Armstrong, Adam Levin, Kaltum Ahmed, Gustavo A Angarita, Brooke J Arterberry, Cecilia Bergeria, Mitch Earleywine, Kathryn S Gex, Tom Gregoire, Jamey J Lister, David S Mathai, Nicky J Mehtani, Nathan Menke, Charles D Nichols, Hillary Shaub, Alayna P Tackett, Brandon Weiss, Nefize Yalin, Lawrence D Phillips

Faculty, Staff and Students Publications

Background: United States drug policy is primarily based on the Controlled Substances Act of 1970 and largely contradicts scientific evidence about how to mitigate drugs’ harms. Expert consensus on drug harms could inform policy that improves the health of people who use drugs while reducing negative societal impacts of drug use. Therefore, this study adapted and extended the relevant 2010 United Kingdom multi-criteria decision analysis, rating drug harms by criteria comprising health and social impacts to people who use drugs and their families, communities, and society.

Methods: Seventeen experts on drug use in the US, including three with lived experience …

Reimagining Pain: The Role Of Mental Imagery In Pain Experience, Jemma Todd, Louise Sharpe, Julie Ji, Brydee Pickup, Tessa Rooney, Emily A Holmes

School of Psychology

No abstract provided.

The Original E-Discovery: Civil Justice Reform And A Return To The Equitable Origins Of Discovery, Patricia I. Mcmahon

Osgoode Hall Law Journal

In the autumn of 2023, the Chief Justice and Attorney General of Ontario announced a broad new effort to review the rules of civil procedure to make civil dispute resolution more efficient and less expensive to enhance access to justice in the province. However, such efforts to reform the rules of civil procedure are nothing new.

This article examines the historical and contemporary aspects of civil justice reform in Ontario, focusing on the pre-trial discovery process. Among the most expensive aspects of the civil litigation process, discovery began as an equitable tool, with roots in the English Court of Chancery. …

Re: Conditional Approval For The Butte Priority Soils Operable Unit (Bpsou) Revised Unreclaimed Sites Ur-08 (Anderson Shaft) – Remedial Action Work Plan (Rawp) (Dated October 24, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Revised Draft Final 2022 Unreclaimed Sites Sampling: Ur-20 Site Evaluation Summary Report (Dated October 24, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Revised Draft Final 2022 Insufficiently Reclaimed Sites Sampling: Bres No. 37 – Josephine Shaft Site Evaluation Summary Report (Dated October 16, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Revised Draft Final 2022 Insufficiently Reclaimed Sites Sampling: Bres No. 38 – Sister Dump Site Evaluation Summary Report (Dated September 30, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Revised Draft Final 2022 Unreclaimed Sites Sampling: Ur-13 Site Evaluation Summary Report (Dated October 22, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Harmonizing Self-Reported And Free Text Medication Data: A Reproducible Pipeline For Gerontological Research, Ramkrishna K Singh, Chen Chen, Semere Bekena, David C Brown, Kaylin Taylor, Matthew Blake, Yiqi Zhu, Kebede Beyene, David B Carr, Ganesh M Babulal

2020-Current year OA Pubs

BACKGROUND: Self-reported medication data collected as free text in gerontological and dementia research is often unstructured with inconsistent formatting. These circumstances pose a challenge for standardization and classification when preparing effective, reproducible analyses. Spelling variations, naming conventions, and reporting drug combinations can hinder mapping to standard pharmacologic vocabularies and compromise medication exposure assessments. We aimed to develop and implement a transparent, reproducible, and scalable data harmonization pipeline that ingests free-text medication records and classifies them according to American Hospital Formulary Service (AHFS) therapeutic categories. METHODS: A four-phase curation pipeline processed 30,062 Research Electronic Data Capture (REDCap) medication records collected over …

Ultrasound-Guided Diffuse Optical Tomography: An Adjunct To Ultrasound That Can Reduce Unnecessary Breast Biopsies, Quing Zhu, Debbie Bennett, Ian S Hagemann, Jaimee Mannix, Kimberly Wiele, Megan Luther, Jingqin Luo, Steven P Poplack

2020-Current year OA Pubs

BACKGROUND: Breast biopsy is recommended for any lesion in which the radiologist deems the likelihood of malignancy to be greater than 2% and more than 75% of biopsies return with benign results. This study assesses whether the total hemoglobin concentration (HbT) and blood oxygen saturation (%sO2) of malignant and benign breast lesions, obtained using Ultrasound-guided diffuse optical tomography (US-guided DOT), can help reduce benign breast biopsy rates. METHODS: 238 women consecutively recruited were examined with US-guided DOT before their US-guided biopsy. Three or four radiologists independently provided BI-RADS assessments using pre-procedure US and mammography (when available), first without and then …

Nutrition Support Adequacy In Children With Biliary Atresia After Liver Transplant, Nicole Knebusch, Manpreet Virk, Moreshwar S Desai, Marwa Mansour, Stacey Beer, Brittany Pearo, Kelby Fuller, Krupa Mysore, John Goss, Thomas Fogarty, Fernando Stein, Jorge A Coss-Bu

Faculty, Staff and Students Publications

No abstract provided.

An Integrated Platform For Concurrent Structural And Single-Nucleotide Variants Improves Copy-Number Detection And Reveals Pathogenic Alleles In Undiagnosed Mendelian Families, Haowei Du, Ming Yin Lun, Lidiia Gagarina, Jesse D Bengtsson, Christopher M Grochowski, Michele G Mehaffey, James Paul Hwang, Shalini N Jhangiani, Sravya V Bhamidipati, Donna M Muzny, M Cecilia Poli, Sebastian Ochoa, Ivan K Chinn, Anna Lindstrand, Jennifer E Posey, Richard A Gibbs, Pengfei Liu, James R Lupski, Claudia M B Carvalho

Faculty, Staff and Students Publications

Background: Copy number variation (CNV) is a class of genomic structural variation (SV) that contributes to genomic disorders and can significantly impact health. Short-read genome sequencing (sr-GS) enables genome-wide SV calling which has been shown to increase diagnosis in unsolved rare disease families. The growing number of large sequencing cohort projects with sr-GS data available requires open free analytical tools that provide visualization of CNV and SV integrated calls associated with gene annotation, proband-parent trio analysis to enable prioritization of de novo variants, B-allele frequency (BAF) plots to support CNV calls, parent of origin assessment and mosaicism detection.

Methods: To …

Eata Mediated Degradation Of Intestinal Mucus Is Species-Specific And Driven By Muc2 Structural Features, Sergio Trillo-Muyo, Brendan Dolan, Frida Svensson, Tim J Vickers, Liisa Arike, Maria-Jose García-Bonete, Jenny K Gustafsson, Mathias I Nielsen, Hans H Wandall, James M Fleckenstein, Gunnar C Hansson, Sjoerd Van Der Post

2020-Current year OA Pubs

Enterotoxigenic Escherichia coli (ETEC) infections are a leading cause of diarrheal illness, responsible for an estimated 100,000 deaths annually. ETEC pathogenesis is driven by various virulence factors, including toxins, adhesins, and noncanonical factors such as the protease EatA. The first line of host defense against intestinal pathogenic bacterial infections is the protective intestinal mucus layer. Here, we demonstrate the mechanism by which EatA degrades the core mucus component MUC2, thereby facilitating access to the epithelial cell surface and promoting infection. We identify the specific cleavage site region localized at the C-terminal of MUC2. EatA's protease activity depends on the interaction …

Membrane Il-18 Identifies A Human Macrophage Subset With Distinct Proteomic And Functional Traits, Chiara Vitale, Marco Colonna, Et Al.

2020-Current year OA Pubs

This study contributes to the characterization of human macrophages in normal and pathological conditions such as cancer. We characterized a macrophage population expressing membrane-associated IL-18 (mIL-18) that shows peculiar proteomic, phenotypic, ultrastructural, and functional properties. mIL-18+ macrophages exhibit increased levels of key proteins involved in pathogen recognition, activation, migration, and endocytosis. They also display specialized functions in vesicle and actin filament transport and lipid metabolism, and have typical mitochondrial traits. Importantly, mIL-18+ cells dominate the peritoneal fluid of adult cancer patients and are present in the bone marrow of children with neuroblastoma. They express high levels of TREM2 but display …

Penggunaan Media Pembelajaran Kahoot Untuk Meningkatkan Motivasi Belajar Siswa Pada Pembelajaran Ips Di Smp, Fara Wahyu Aziza, Galuh Raka Prana, Hanifa Nur Fadhilah, Indah Nor Janah, Maria Rut Ningsi Arakian, Ni Gusti Nyoman Desianti, Syamsul Bachri, Ria Nuzul Fahrudin

Journal of Innovation and Teacher Professionalism

One of the main challenges in junior high school Social Studies is low student motivation. Many students perceive the subject as heavily based on memorization, making it feel monotonous and less engaging. To address this problem, the study aimed to analyze the effectiveness of Kahoot! as an instructional medium for increasing student motivation in Social Studies at SMP Negeri 13 Malang. A qualitative descriptive approach was used with Grade IX students as participants. Data were collected through observation, interviews, and documentation and analyzed using an interactive model consisting of data reduction, data display, and conclusion drawing. The findings showed that …

Efektivitas Pendekatan Teaching At The Right Level (Tarl) Dalam Meningkatkan Hasil Belajar Siswa Kelas V Sekolah Dasar, Nur Azlina, Putri Rohadatul Aisy, Siti Mas'ula

Journal of Innovation and Teacher Professionalism

This study aimed to analyze the effectiveness of the Teaching at the Right Level (TaRL) approach in improving learning outcomes in Natural and Social Sciences among Grade V students at SDN Sawojajar 5 Malang. It used a quantitative pre-experimental method with a One-Group Pretest–Posttest design. The participants were 28 students from Grade V-A selected through purposive sampling. Data were collected using pretest and posttest instruments as well as observation. The average pretest score was 60.36, while the average posttest score after the TaRL intervention was 91.43. Hypothesis testing produced a Sig. (2-tailed) value of 0.000, lower than 0.05, indicating that …

Strategi Culturally Responsive Teaching Dalam Pembelajaran Ips Untuk Meningkatkan Kesadaran Kebinekaan Global, Elvira Zulfah Aliyah, I Nyoman Ruja, Muktiningsih Muktiningsih

Journal of Innovation and Teacher Professionalism

A Grade VIII Social Studies teacher at SMPN 2 Malang implemented a Culturally Responsive Teaching (CRT) approach based on the local culture of Greater Malang to strengthen the global diversity dimension of the Pancasila Student Profile. This study aimed to: (1) examine the implementation of CRT in Social Studies learning and (2) identify opportunities and challenges in its application. A qualitative descriptive method was used with Grade VIII-F students at SMPN 2 Malang as participants. Data were collected through observation, interviews, and documentation. The Miles and Huberman model was used for data analysis, while data validity was examined through time …

Pengembangan Domino Adventure Dengan Model Teams Games Tournament Melalui Pendekatan Design Thinking Pada Pembelajaran Perubahan Wujud Zat Kelas Viii, Risca Shintya Putri, Avida Imatus Solikhah, Imma Silvia Yustiani, Mamik Masusil Qoiriyah, Ririn Setiyani, Supriyadi Supriyadi, Oktavia Sulistina

Journal of Innovation and Teacher Professionalism

The learning process is strongly influenced by student motivation, which plays an important role in determining instructional effectiveness. Learning methods that tend to be monotonous, such as lectures or excessive assignments, may negatively affect students’ understanding. Therefore, more interactive and enjoyable approaches are needed to improve student participation and learning outcomes. One model that can be applied is game-based learning, such as Teams Games Tournament (TGT). This study developed instructional materials using the Design Thinking method, which considers emotional, aesthetic, and interaction-related aspects between the system and its users. The main objective was to develop the Domino Adventure game medium …

Pemanfaatan Nearpod Sebagai Media Pembelajaran Matematika Berbasis Gamifikasi Pada Materi Segitiga Dan Segi Empat Kelas Viii Smp, Intan Faraminda Putri, Erry Hidayanto, Sri Indayani

Journal of Innovation and Teacher Professionalism

Low student motivation is a major challenge in education today, particularly in mathematics. One solution is to use gamification-based instructional media such as Nearpod. The application offers interactive features, including quizzes, polls, simulations, and dynamic presentations, which can create an enjoyable and engaging learning environment. This study employed a qualitative approach to explore the benefits of using Nearpod in mathematics instruction. The participants were 32 students in Grade VIII-H at SMPN 18 Malang. Data were collected through open-ended surveys and observations of student activities during lessons. The findings showed that Nearpod improved students’ understanding of triangles and quadrilaterals, created a …

Peningkatan Partisipasi Aktif Dalam Pembelajaran Melalui Metode Problem Solving Dan Penerapan Gaya Belajar Secara Visual Pada Siswa Kelas 11 Pekerjaan Sosial, Zulfa Kholila, Zulkarnain Zulkarnain, Anita Sylvi Yuspitarini

Journal of Innovation and Teacher Professionalism

This article describes efforts to increase students’ active participation in the learning process among Grade XI Social Work students at SMKN 2 Malang during the 2023/2024 academic year. Active participation was promoted through the problem-solving method and the use of visual learning strategies during classroom instruction. The study employed classroom action research. The participants were 32 Grade XI Social Work students at SMKN 2 Malang, while the research focus was their active participation during lessons. Data were collected through observation, interviews, and documentation, then analyzed descriptively and presented in tables. The findings showed an increase in active participation from Cycle …

Penggunaan Wordwall Pada Pembelajaran Pendidikan Jasmani Olahraga Dan Kesehatan Siswa Kelas 1 Sd Laboratorium, Ragita Febriansyah, Gema Fitriady, Anang Marzuqi

Journal of Innovation and Teacher Professionalism

Education is an important aspect of society because it improves the quality of human resources and expands opportunities for individual success. In this context, Physical Education, Sports, and Health at the elementary school level plays a crucial role in students’ holistic development. However, teaching this subject in Grade I can be challenging because instruction must be appropriate to students’ developmental stages and varied learning styles. In the information technology era, digital learning media such as Wordwall offer considerable potential for improving instructional effectiveness. This study analyzed the use of Wordwall in Grade I Physical Education, Sports, and Health instruction and …

Penerapan Scaffolding Pada Zone Of Proximal Development Dalam Pembelajaran Sejarah Kelas X Ips, Ika Wara Yuni Antisna, Joko Sayono

Journal of Innovation and Teacher Professionalism

Effective teaching is an ideal form of instruction that optimizes students’ abilities. Various instructional strategies can be applied to achieve optimal learning outcomes, one of which is scaffolding. This study aimed to analyze the implementation of scaffolding within the Zone of Proximal Development (ZPD) in history instruction for Grade X Social Sciences 3 at SMA Laboratorium UM and to evaluate its impact on students’ understanding and learning independence. The study used a qualitative descriptive approach. Data were obtained through observation, interviews, and document analysis. The findings showed that scaffolding was highly important in history learning because students still required teacher …

Penerapan Media Card Education Output Untuk Meningkatkan Keterlibatan Aktif Siswa Smp Pada Materi Mengapresiasi Kebudayaan Lokal, Thania Carolline, Abd. Mu'id Aris Shofa

Journal of Innovation and Teacher Professionalism

This study aimed to explore the use of various instructional media to support effective classroom learning. A qualitative descriptive case-study approach was employed. The participants were 30 Grade X students at SMP Muhammadiyah 01 Malang. Data were collected through classroom observations, interviews with teachers and students, and analysis of learning documents. Data were analyzed using the Miles and Huberman interactive model, which includes data reduction, data display, and conclusion drawing. The findings showed that the use of varied instructional media, including social media and digital technology, increased student engagement and enriched their learning experiences. Traditional instructional media also continued to …