Process Control and Systems Commons^™

Limits Of Detection Of Mycotoxins By Laminar Flow Strips: A Review, Xinyi Zhao, Hugh Byrne, Christine M. O’Connor, James Curtin, Furong Tian

Articles

Mycotoxins are secondary metabolic products of fungi. They are poisonous, carcinogenic, and mutagenic in nature and pose a serious health threat to both humans and animals, causing severe illnesses and even death. Rapid, simple and low-cost methods of detection of mycotoxins are of immense importance and in great demand in the food and beverage industry, as well as in agriculture and environmental monitoring, and, for this purpose, lateral flow immunochromatographic strips (ICSTs) have been widely used in food safety and environmental monitoring. The literature to date describing the development of ICSTs for the detection of different types of mycotoxins using …

Model-Guided Design Of Rna-Based Synthetic Circuits For The Dynamic Regulation Of Gene Expression, Jordan R. Ryan

LSU Master's Theses

A longstanding goal in synthetic biology has been to build synthetic gene circuits with the ability to harness nature’s capability of precise gene expression regulation. Advancements in RNA technology have established RNA-based regulators with distinct advantages over traditional protein-based regulators such as faster signal propagation, versatile programmability, and low cellular burden, which has created an interest in the field to construct innovative synthetic gene circuits using de novo RNA- based regulators. However, our understanding of the behavior and kinetics of RNA-RNA interactions for the construction of gene circuits is incomplete. This thesis proposes a model-guided design framework that integrates mechanistic …

Lyapunov-Based Economic Model Predictive Control For Detecting And Handling Actuator And Simultaneous Sensor/Actuator Cyberattacks On Process Control Systems, Henrique Oyama, Dominic Messina, Keshav Kasturi Rangan, Helen Durand

Chemical Engineering and Materials Science Faculty Research Publications

The controllers for a cyber-physical system may be impacted by sensor measurement cyberattacks, actuator signal cyberattacks, or both types of attacks. Prior work in our group has developed a theory for handling cyberattacks on process sensors. However, sensor and actuator cyberattacks have a different character from one another. Specifically, sensor measurement attacks prevent proper inputs from being applied to the process by manipulating the measurements that the controller receives, so that the control law plays a role in the impact of a given sensor measurement cyberattack on a process. In contrast, actuator signal attacks prevent proper inputs from being applied …

Lyapunov-Based Economic Model Predictive Control For Online Model Discrimination, Henrique Oyama, Helen Durand

Chemical Engineering and Materials Science Faculty Research Publications

Economic model predictive control (EMPC) is a flexible control design strategy that can be modified to achieve many operating goals while also ensuring safe operation (e.g., by adding Lyapunov-based stability constraints to form Lyapunov-based EMPC, or LEMPC). Prior works have investigated LEMPC capabilities for achieving goals online beyond optimizing process economics, including aiding in model structure selection to benefit model-based control system design since the accuracy and quality of the process model are important for achieving an expected performance from such systems. This work further probes the capabilities of LEMPC to accomplish multiple objectives during process operation, including aiding in …

Microcystin-Lr Removal From Water Via Enzymatic Linearization And Ultrafiltration, Abelline Fionah, Cannon Hackett, Hazim Aljewari, Laura Brady, Faisal Alqhtani, Isabel C. Escobar, Audie K. Thompson

Chemical Engineering Faculty Publications and Presentations

Microcystin-LR (MC-LR) is a toxin produced by cyanobacteria that can bloom in freshwater supplies. This study describes a new strategy for remediation of MC-LR that combines linearization of the toxin using microcystinase A, MlrA, enzyme with rejection of linearized byproducts using membrane filtration. The MlrA enzyme was expressed in Escherichia coli (E. coli) and purified via a His-tag with 95% purity. Additionally, composite membranes made of 95% polysulfone and 5% sulfonated polyether ether ketone (SPEEK) were fabricated and used to filter a solution containing cyclic and linearized MC-LR. Tests were also performed to measure the adsorption and desorption of MC-LR …

Design And Control Of Intensified Membrane Reactor Systems Through Module-Based Design Approach, Brent Bishop

Graduate Theses, Dissertations, and Problem Reports (ETD)

As interest in the modularization and intensification of chemical processes continues to grow, more research must be directed towards the modeling and analysis of intensified process units. Intensified process units such as membrane reactors pose unique challenges pertaining to design and operation that have not been fully addressed in the reported literature. This work aims to address the design and control challenges caused by the integration of phenomena and the loss of degrees of freedom (DOF) that occur in the intensification of modular membrane reactor units.

First, a novel first-principles approach for modeling membrane reactors is developed using the AVEVA …

Reinforcement Learning For Process Control: Applications To Energy Systems, Elijah Ballard Hedrick

Graduate Theses, Dissertations, and Problem Reports (ETD)

Reinforcement learning (RL) is a machine learning method that has recently seen significant research activity owing to its successes in the areas of robotics and gameplaying (Silver et al., 2017). However, significant challenges exist in the extension of these control methods to process control problems, where state and input signals are nearly always continuous and more stringent performance guarantees are required. The goal of this work is to explore ways that modern RL algorithms can be adapted to handle process control problems; avenues for this work include using RL with existing controllers such as model predictive control (MPC) and adapting …

Broadband Dielectric Spectroscopic Detection Of Ethanol: A Side-By-Side Comparison Of Zno And Hkust-1 Mofs As Sensing Media, Papa K. Amoah, Zeinab Mohammed Hassan, Pengtao Lin, Engelbert Redel, Helmut Baumgart, Yaw S. Obeng

Electrical & Computer Engineering Faculty Publications

The most common gas sensors are based on chemically induced changes in electrical resistivity and necessarily involve making imperfect electrical contacts to the sensing materials, which introduce errors into the measurements. We leverage thermal- and chemical-induced changes in microwave propagation characteristics (i.e., S-parameters) to compare ZnO and surface-anchored metal-organic-framework (HKUST-1 MOF) thin films as sensing materials for detecting ethanol vapor, a typical volatile organic compound (VOC), at low temperatures. We show that the microwave propagation technique can detect ethanol at relatively low temperatures (<100 >°C), and afford new mechanistic insights that are inaccessible with the traditional dc-resistance-based measurements. In addition, …

Uncertainty Of The Ultrasonic Method For Determining The Strength Of Concrete, Ortagoli Sharipovich Hakimov, Zamira Khudoyberdiyevna Ernazarova

Chemical Technology, Control and Management

The issues of measuring the strength of concrete by the method of surface sounding by ultrasound are considered. A measurement model and formulas for estimating the total standard measurement uncertainty, information about the standards used, measurement tools and methods, and environmental parameters are given. Information about the estimation of uncertainty in the form of "eight steps", such as: measurement task; mathematical model of measurement; analysis of input values; observation results; correlations; uncertainty budget; expanded uncertainty; measurement result. It has been established that the uncertainty of type B of the ultrasonic method for determining the strength of concrete is much less …

Mathematical Modeling Of Processes Of Diagnostics Of Technical And Technological Objects, Azizbek Nodirbekovich Yusupbekov, Khurshid Salim Ugli Turayev

Chemical Technology, Control and Management

The work is an introduction to the technical diagnostics of technical (or technological) objects. It discloses the basic concepts and definitions of the reliability of dynamic systems as objects of diagnostic reference knowledge and their diagnosis. Structural schemes of diagnosing objects with individual and combined channels of influence are analyzed. Questions of rational construction of base of reference knowledge are stated.

Virtual Analyzers For Increasing The Intelligence Of Industrial Process Control Systems, Umidjon Abdimajotovich Ruziev Phd, Marufjon Kobuljanovich Shodiev

Chemical Technology, Control and Management

It is shown that the development and implementation of virtual analyzers of the quality of the final industrial products is an effective tool for increasing the efficiency of industrial production. The methodology and stages of development of virtual analyzers for predicting the quality of products, monitoring non-measurable or difficult-to-measure parameters of continuous and periodic technological processes are considered, and issues of supporting and adapting a virtual analyzer during its operation without restructuring are also considered.

Developing Advanced Process Control System For Manufacturing Processes Using Virtual Analyzer, Elyor Erkinovich Samadov

Chemical Technology, Control and Management

This research reflects outlines the main potential features of Advanced Process Control (APC) systems for improved control of technological processes and production. It is shown developing APC systems using a virtualized analyzer (VA) is a very effective technique to increase the efficiency of industrial production. This research reflects the main steps of generating VA as part of the APC system and also describes the key features of each step-in terms of analyzer synthesis.

Design Lifecycle Management Of Technological Processes, Yusuf Shodiyevich Avazov

Chemical Technology, Control and Management

The issues of life cycle management of design processes of complex technological processes are considered. An analysis of works devoted to the automated design of technological processes and industries, product life cycle management, and the use of predominant modeling in design is presented. A structure for the implementation of the design of technological processes is proposed and it’s components are described. An algorithm is proposed to reduce the life cycle of the design of a technological process. The sequence of selection of the most optimal project options with the help of the proposed algorithm is described. It is shown that …

Predictive Analysis And Synthesis, Modeling And Control Of Complex Technological Processes And Systems, Zhahongir Sherboyevich Bekqulov

Chemical Technology, Control and Management

Consider the theoretical underpinnings of practically predictive analysis and synthesis, modeling and automatic control of complex chemical technological processes and systems, and the evolution of advanced (or advanced) APC (Advanced Process Control) control of technological processes and industries. The current state of industrial automation systems and the characteristics of their deployment are highlighted. The features of each stage of the analysis and synthesis of APC - advanced process control for complex dynamic objects are disclosed. The real situation and features of the implementation of industrial automation systems of industrial enterprises are reflected.

New Transformer Changer Static Characteristics Measuring Angle Silences Difference, Sultan Faizullayevich Аmirov, Nurulla Raxmatullayevich Yuldashev

Chemical Technology, Control and Management

Presented the specific features of the new transformer converter, which measures the difference in angular displacement, and examines the nonlinearity levels of static characteristics, sensitivity and static characteristics. Studies have shown that in a new measuring device, where one of the two moving parts consists of a magnetic conductor made in the form of an Archimedean spiral made of ferromagnetic material, the balance of the magnetic bridge changes not only depending on the angle of rotation of it’s shoulder resistances. the current is disturbed by the change in the magnitude of the combined air gap depending on the angle of …

Quality Control Of Combustion Of Gaseous Fuel In Furnaces, Azamat Toirovich Rajabov

Chemical Technology, Control and Management

The issues of research and development of systems for monitoring the availability and quality of the process of fuel combustion in industrial furnaces are interpreted. The perspective of using new elements in control systems - communication sensors for the presence and quality in gas-burning installations and furnaces are shown. A method has been developed to control the optimal aeration coefficient based on the extreme of the total integral amplitude-frequency characteristic of the flame conductivity pulsations, which makes it possible to control the quality characteristics of gas-burner devices and control the ratio of the components of the combustible mixture with high …

Algorithm For Calculating The Parameters Of A Multi-Position Electromagnetic Linear Mechatronic Module, Nazarov Khayriddin Nuritdinovich, Matyokubov Nurbek Rustamovich, Temurbek Omonboyevich Rakhimov

Chemical Technology, Control and Management

Currently, in the world in the field of science, engineering and technology, including in mechatronics and robotics, the creation of multi-coordinate mechatronic systems that perform power and control functions is becoming of paramount importance, this is due to a number of important positive qualities of the systems, such as simplicity and compactness of the design, the possibility of obtaining significant efforts, high accuracy and stability of the establishment of fixed positions, ease of control and high reliability. This article presents the calculation of the parameters of multi-position mechatronic modules based on linear execution elements. In the construction of this model, …

Regular Algorithms For Adaptive Identification Of Linear Non-Stationary Systems, H.Z. Igamberdiyev, H.I. Sotvoldiev, U.F Mamirov

Chemical Technology, Control and Management

The article deals with the formation of regular algorithms for adaptive parametric spline identification of linear non-stationary systems. Analyzed the issues of constructing adaptive identification of continuous linear non-stationary systems with monotonic and sign-constant parameters. In this case, in a non-stationary system, the entire observation interval is in some way divided into sub-intervals. Identification is carried out at each of the parameter constancy intervals, while the parameter matrix is re-evaluated for the next interval. The input data of the system are determined with an error depending on the error of approximating the state of the system by splines and approximating …

Real-Time Monitoring Of Cell Death Progress Using Capacitance Spectroscopy, Suyang Wu

Electronic Theses and Dissertations

Biologics, including the monoclonal antibody (mAb), has experienced rapid development in the last decade. However, the price of biologics is often prohibitively high because of the low process efficiency. Delaying the inevitable cell death improves the productivity of upstream bioprocessing, whose success relies on monitoring the cell death onset that indicates the timing for preventive actions.

This study proposes to develop a real-time monitoring model that quantifies the dying cell percentage in lab-scale bioreactors using capacitance spectroscopy. The capacitance spectroscopy contains cell death-related information due to various physical properties changes during the cell death process, e.g., cytoplasmic conductivity change. The …

Control Of The Facial Design Process Of Innovative Developments, Yusuf Shodiyevich Avazov

Chemical Technology, Control and Management

The role and place of visual design in the process of creating an innovative development have been stated. It is shown that the tasks of the face stage of the product life cycle are devoted to systemic issues, in the center of which is the resolution of the contradiction between the desired and the achievable. The first is determined by the need to create a new system of a higher level, and the achievable is determined by the level of development of science, technology and production technology, as well as by the conditions of operation and repair. The work is …