Chemical Engineering Commons^™

Gait Rehabilitation Using Functional Electrical Stimulation Induces Changes In Ankle Muscle Coordination In Stroke Survivors: A Preliminary Study, Jessica L. Allen, Lena H. Ting, Trisha M. Kesar

Faculty & Staff Scholarship

No abstract provided.

The Creation, Validation, And Implementation Of The Engineering Process Safety Research Instrument, Brittany Lynn Butler

Theses and Dissertations

The purpose of this study was to develop and validate an instrument that can measure how senior chemical engineering students make process safety decisions. The Engineering Process Safety Research Instrument (EPSRI) contains dilemmas that represent process safety scenarios, followed by three decision options, and 12-15 considerations that fall into pre-conventional, conventional, or post-conventional forms of reasoning. Three studies were completed as a part of this research. The content validation study ensured the dilemmas represented process safety scenarios, the considerations matched their perceived theoretical definitions, and that no content areas were omitted. This study resulted in validation of the content, following …

Determination Of Chemical Speciation Of Arsenic And Selenium In High-As Coal Combustion Ash By X-Ray Photoelectron Spectroscopy: Examples From A Kentucky Stoker Ash, Biao Fu, James C. Hower, Shifeng Dai, Sarah M. Mardon, Guijian Liu

Center for Applied Energy Research Faculty and Staff Publications

Knowledge of the chemical speciation of arsenic and selenium in coal fly ash is essential in the evaluation of the environmental behavior of fly ash disposed in a landfill in a natural environment. In this study, a series of high-As coal fly ash from stoker boilers were collected to determine the chemical forms of arsenic and selenium. The ash surface chemical characteristics and the speciation of arsenic and selenium were characterized by X-ray photoelectron spectroscopy and X-ray-induced Auger electron spectroscopy. The results indicate that the surface enrichment ratio for selenium (63.3–309.5) is higher than that of arsenic (1.2–21.2). The Wagner …

Temperature Transient Analysis For Reservoir Characterization, Yilin Mao

LSU Doctoral Dissertations

Recent developments in downhole temperature measurements open new alternatives contributing to reservoir characterization. In this dissertation, novel forward and inverse models to analyze production- and injection-induced temperature signals are developed for conventional and unconventional reservoir applications. Important limitations of the proposed models are addressed by accounting for fluid property variations and complex production strategies.

Forward modeling approaches involve making relevant assumptions that allow rigorous analytical solutions to be constructed using Laplace transform, Method of Characteristics, and control volume analysis. Our results of the analytical models are benchmarked with those from commercial numerical simulation software. Multiple possible scenarios of conventional reservoirs …

Graphene Oxides In Water: Characterization, Reactivity, And Application, Siyuan An

McKelvey School of Engineering Graduate Student Theses & Dissertations

Recently discovered, graphene and graphene oxide materials have drawn considerable research attention due to outstanding and novel properties, which underpin wide material potential for a number of advanced applications including supercapacitors, solar cells, sensors, catalysts, semiconductors, sorbents, and membranes, among others. Graphene oxides (GO), which are considered as a family of oxidized graphene materials (derivatives), is a key precursor to the synthesis of free-standing graphene via oxidation-exfoliation-reduction pathways. GO properties depend on the synthesis routes/conditions (i.e. derivatization), including partially maintaining graphene (i.e. sp2) properties. Further, oxygen-containing functionalities (epoxy, hydroxyl, carbonyl, and carboxyl groups) render GO hydrophilic – and correspondingly stability …

Investigating Cyanobacteria Metabolism And Channeling-Based Regulations Via Isotopic Nonstationary Labeling And Metabolomic Analyses, Mary Helen Abernathy

McKelvey School of Engineering Graduate Student Theses & Dissertations

Cyanobacteria have the potential to be low-cost and sustainable cell factories for bio-products; however, many challenges face cyanobacteria as biorefineries. This dissertation seeks to advance non-model photosynthetic organisms for biotechnology applications by characterizing central carbon metabolism and its regulations. Cyanobacteria phenotypes for bio-production are examined and their intracellular metabolism is quantified. Using isotopic labeling experiments, phenotypic relationships between biomass composition, central carbon fluxes, and metabolite pool sizes are investigated. Metabolic analyses of cyanobacteria led to new investigations of flux regulation mechanisms via protein spatial organizations or metabolite channeling. Metabolite channeling is further explored as a hypothesis to explain enigmatic labeling …

Mechanisms Of Calcium Phosphate Mineralization On Biological Interfaces And Their Engineering Applications, Doyoon Kim

McKelvey School of Engineering Graduate Student Theses & Dissertations

All living organisms utilize phosphorus (P) as an essential component of their cell membranes, DNA and RNA, and adenosine triphosphate. Bones, in addition to bearing loads, play an important role in balancing P levels in our bodies. In bones, a network of collagen templates and calcium phosphate (CaP) nanocrystals builds hierarchical levels, from nano- to macroscale. Within this architecture, the thermodynamic properties of CaP minerals are influential. Despite the importance of nucleation, growth, and crystallization in collagen structures for tissue development, little kinetic study of these processes has been conducted due to the limited in situ techniques for monitoring these …

Decoding Complexity In Metabolic Networks Using Integrated Mechanistic And Machine Learning Approaches, Tolutola Timothy Oyetunde

McKelvey School of Engineering Graduate Student Theses & Dissertations

How can we get living cells to do what we want? What do they actually ‘want’? What ‘rules’ do they observe? How can we better understand and manipulate them? Answers to fundamental research questions like these are critical to overcoming bottlenecks in metabolic engineering and optimizing heterologous pathways for synthetic biology applications. Unfortunately, biological systems are too complex to be completely described by physicochemical modeling alone.

In this research, I developed and applied integrated mechanistic and data-driven frameworks to help uncover the mysteries of cellular regulation and control. These tools provide a computational framework for seeking answers to pertinent biological …

Cfd Modeling Of Smoke Movement In An Atrium, Robin Wu

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this paper is to better understand the behavior of smoke movement in an atrium. Thus gives first responders and civilians in and out of building a better understanding

With the advancements of modern technology, computers and softwares make simulation models possible such as fire models to simulate fire and smoke movements. In this paper, a computational fluid dynamic (CFD) software Fire Dynamic Simulator (FDS) is used to conduct a series of atrium tests to investigate the effectiveness of smoke exhaust systems. FDS solves the Navier-Stokes equations appropriate for low speed flows (Ma < 0.3) with an emphasis on smoke, heat transport and CO2 concentrations from fires. The default turbulence model used in FDS simulation is the Large Eddy Simulation (LES), which is the solution of Navier-Stokes equations at low speed.

The compartment tested was 9 …

Enhanced Anticancer Activity Of 5'-Dfur-Pcl-Mpeg Polymeric Prodrug Micelles Encapsulating Chemotherapeutic Drugs, Alicia J. Sawdon, Jun Zhang, Xutu Wang, Ching-An Peng

Department of Chemical Engineering Publications

The compound 5’-deoxy-5-fluorouridine (5’-DFUR) is a prodrug of the anti-tumor drug 5-fluorouracil (5-FU). Thymidine phosphorylase (TP) is an enzyme that can convert 5’-DFUR to its active form 5-FU and the expression of TP is upregulated in various cancer cells. In this study, 5’-DFUR associated with amphiphilic copolymer poly(ε-caprolactone)-methoxy poly(ethylene glycol) (5’-DFUR-PCL-MPEG) was synthesized, characterized, and self-assembled into functional polymeric micelles. To demonstrate that the prodrug 5’-DFUR could convert into cytotoxic 5-fluorouracil (5-FU) by endogenous TP, HT-29 colorectal cancer cells were treated with 5’-DFUR-PCL-MPEG polymeric micelles for various time periods. Chemotherapeutic drugs doxorubicin (DOX) and 7-ethyl-10-hydroxycamptothecin (SN-38) were also encapsulated separately …

Exploring Structure-Property Relationships Of Gags To Tailor Ecm-Mimicking Hydrogels, Ralf Zimmermann, Carsten Werner, James Sterling

Business and Information Technology Faculty Research & Creative Works

Glycosaminoglycans (GAGs) are a class of linear polysaccharides that are ubiquitous in the extracellular matrix (ECM) and on cell surfaces. Due to their key role in development, homeostasis, pathogenesis, and regeneration, GAGs are increasingly used in the design of ECM-mimicking hydrogels to stimulate tissue formation and regenerative processes via specifically orchestrated cell-instructive signals. These applications first and foremost build on the ability of GAGs to effectively bind, protect, and release morphogens. The specificity and strength of morphogen-GAG interactions are largely governed by the number and spatial distribution of negatively charged sulfate groups carried by GAGs. Herein, we summarize a mean-field …

An Improved Method To Calculate Gas-Lift Valve Set Pressure And Valve Performance Curves, Khadhr A Kh Altarabulsi

LSU Doctoral Dissertations

The main objective of this work is toimprove the accuracy on calculations of design set pressure and performance curves (sizing equations) for Gas-Lift Valves (GLVs) at high pressure (real conditions). This improved calculation method is demonstrated to have an important effect on well unloading and production operations.

The analysis of the valve design set pressure includes an experimental evaluation of the effect of internal dome volume changes on the design set pressure due to the presence of silicone and thermal effects. The evaluationis carried out for different levels of GLV silicone fill, pressures and temperatures. Silicone fills covered 7.5, 10, …

Laser Vaporization And Controlled Condensation (Lvcc): Graphene Supported Pd/Fe3o4 Nanoparticles As An Efficient Magnetic Catalyst For Suzuki Cross – Coupling., Hany A. Elazab Dr

Chemical Engineering

A reproducible, reliable, and highly efficient synthetic approach was implemented for synthesis of palladium nanoparticles supported on a binary composite of Fe3O4 and graphene (Pd-Fe3O4/G). This unique catalyst was tested for being used as a highly efficient active catalyst for being used in Suzuki cross – coupling reactions. It was found that this graphene supported Pd/Fe3O4 nanoparticles (Pd-Fe3O4/G) has a remarkable catalytic activity towards Suzuki coupling reactions. This catalyst could be recycled for up to three times with high catalytic activity. The catalyst was prepared using LVCC synthetic approach; the prepared catalyst was found to be highly magnetic which enabled …

Micro Reactor Technology: Flow Chemistry Impact On Applied Catalysis, Hany A. Elazab Dr

Chemical Engineering

The micro reaction technology has emerged over the past two decades as one of the promising synthetic tools that can create new horizons in many industrial and catalysis applications. There are many crucial issues that could simply be solved by adopting the approach of micro reaction technology. Those issues are including harmful environmental impact which could be minimized through integrated separation techniques and reagent recycling used in micro reactors. There are also other issues including kinetic, thermodynamic, and process safety concerns. Moreover, chemical manufacturing has been enhanced through running reactions in continuous mode using flow chemistry. This lead to a …

Community-Scale Water Treatment Systems In The Dominican Republic, Jonathan Racey, Annabelle Papai, Elise Fischer, Becca Johnson

Engagement & Service-Learning Summit

Engagement and Service-Learning Summit: Reciprocal and Sustainable Partnerships

Exploring Large Pore Size Alumina And Silica-Alumina Based Catalysts For Decomposition Of Lignin, Sara Pourjafar, Jasmine Kreft, Honza Bilek, Evguenii Kozliak, Wayne Seames

Chemical Engineering Faculty Publications

Evaluation of copper doped silica-alumina and γ-alumina catalysts for lignin decomposition was conducted using a suite of chemical analysis protocols that enabled a comprehensive characterization of the reaction product. X-ray diffraction analysis was used to verify the concentration of doped copper on catalyst supports. Then, batch experiments were performed to study the significance of catalyst support type, catalyst dopant concentration, lignin concentration, catalyst-to-lignin ratio, reactor stirring rate and reaction time. Aqueous products were extracted with dichloromethane and analyzed using a detailed gas chromatography-mass spectrophotometry analytical protocol, allowing for quantification of over 20 compounds. Solid residues were analyzed by thermogravimetric analysis …

Ascorbic Acid Degradation In Cut Lemon Packaged Using Oxygen Scavenging Active Film During Storage, Kurniawan Yuniarto, Setyo Purwanto, Bruce Ari Welt, Anang Lastriyanto

Makara Journal of Technology

Oxygen scavenging active film can be used to prevent diffusion of free oxygen due to the action of permeation mechanism. In this study, biodegradable oxygen scavenging plastic film was designed by incorporating an antioxidant agent into plasticized polylactic acid or PLA-PEG (PPLA). Butylated hydroxytoluene (BHT) was added at different concentrations into the matrix of the PPLA film using a direct casting method to produce oxygen scavenging active film. The antiradical activity of the oxygen scavenging active film was observed, which could be applied for preventing vitamin C degradation in cut lemon during storage. The antiradical activity of the active film …

Conversion Of Heat Energy From Cooling Water Of Diesel Engine To Electrical Energy Using Thermoelectric Generator, Muhammad Hasan Albana

Makara Journal of Technology

This research objective is to convert heat from the radiator fluid of a diesel engine to electrical energy by utilizing a thermoelectric generator (TEG). The TEG consists of 20 semiconductors (TE modules) and is equipped with a heat sink. The research shows that using the TEG, the heat of radiator fluid can be converted to electrical energy, although the electricity generated is small. The maximum electrical voltage generated by the TEG when modules were connected in series was 10 volts. When the TE modules were connected in parallel and series-parallel, the maximum voltages generated were 2.11 and 2.53 volts, respectively. …

Immittance Response On Carboxymethyl Cellulose Blend With Polyvinyl Alcohol- Doped Ammonium Bromide-Based Biopolymer Electrolyte, Norfatihah Mazuki, Yuki Nagao, Ahmad Salihin Samsudin

Makara Journal of Technology

The blended carboxymethyl cellulose (CMC) and polyvinyl alcohol (PVA) doped with various compositions of ammonium bromide (NH4Br)-based solid biopolymer electrolytes (SBEs) were prepared by using the casting method. In this present work, CMC/PVA–NH4Br SBE thin film was used to investigate the electrical conductivity via electrical impedance spectroscopy. The maximum conductivity obtained was 3.21 X 10−4 S cm−1 for sample AB20 at ambient temperature (303 K), and this result might be due to the increased number of charge carrier. A dielectric study was conducted to understand the conductivity behavior. The electrical properties have been measured as a function of frequency of …

Transition Metal Dichalcogenide For High-Performance Electrode Of Supercapacitor, Saifful Kamaluddin Muzakir, Ahmad Salihin Samsudin, Bouchta Sahraoui

Makara Journal of Technology

Molybdenum dichalcogenides have been reviewed from the perspectives of bandgap, conductivity, and oxidation states of transition metal. Researchers have concluded that a narrow-bandgap transition metal dichalcogenide with high conductivity could be achieved for the high-performance electrode of a supercapacitor.