Study On Antibacterial Of Chitosan/Hydroxyapatite Doped Magnesium Composite As A Material For Bone Graft Applications,
2019
Material and Metallurgical Engineering, Institut Teknologi Kalimantan, Balikpapan 76127, Indonesia
Study On Antibacterial Of Chitosan/Hydroxyapatite Doped Magnesium Composite As A Material For Bone Graft Applications, Andromeda Dwi Laksono, Teodoro A. Amatosa, Jr., Hilda Pebrianti Octaviana Sitorus, Wentika Putri Kusuma Asih, Sulistijono Sulistijono
Makara Journal of Technology
Hydroxyapatite (HAp) is one of the constituent minerals of bone and teeth, that has been widely used for synthesizing bone graft. Due to the limitation on properties of the hydroxyapatite, it is doping with Magnesium (HAp-Mg). The addition of Chitosan (Chi) was expected to improve the antibacterial properties of HAp-Mg. The present research aims to study the influence of Chitosan with 0, 5, 15, and 25 wt% addition on biocompatibility properties of Chi/HAp-Mg composite. HAp-Mg was synthesized using the sol-gel method; meanwhile, Chi/HAp-Mg composite was manufactured by mixing Chitosan in acetic acid, and HAp-Mg was added into the mixture. The …
Evaluation Of Primal-Dual Splitting Algorithm For Mri Reconstruction Using Spatio-Temporal Structure Tensor And L1-2 Norm,
2019
Department of Electrical Engineering, Faculty of Engineering, Universitas Indonesia, Depok 16424, Indonesia
Evaluation Of Primal-Dual Splitting Algorithm For Mri Reconstruction Using Spatio-Temporal Structure Tensor And L1-2 Norm, Mia Rizkinia, Masahiro Okuda
Makara Journal of Technology
Magnetic resonance imaging (MRI) is an essential medical imaging technique which is widely used for medical research and diagnosis. Dynamic MRI provides the observed object visualization through time and results in a spatiotemporal signal. The image sequences often contain redundant information in both spatial and temporal domains. To utilize this characteristic, we propose a spatio-temporal reconstruction approach based on compressive sensing theory. We apply spatio-temporal structure tensor using nuclear norm, in addition to the wavelet sparsity regularization. The spatio-temporal structure tensor is a matrix that consists of gradient components of the MRI data w.r.t the spatial and temporal domains. For …
Acute Toxicitystudy Of Choline Based Ionic Liquids Towards Danio Rerio Fish And The Aggregation Behavior Of Their Binary Mixtures,
2019
Department of Chemical Engineering, Universiti Teknologi PETRONAS, Bandar Seri Iskandar, Perak 32610, Malaysia
Acute Toxicitystudy Of Choline Based Ionic Liquids Towards Danio Rerio Fish And The Aggregation Behavior Of Their Binary Mixtures, Mansoor Ul Hassan Shah, Nasruddin Nasruddin, Suzana Bt Yusup, Muhammad Moniruzzaman
Makara Journal of Technology
Marine oil spills are effectively controlled by chemical dispersants. However, the toxicity associated with it reduce its employment in marine environment. To overcome this limitation, the acute toxicity of choline based ionic liquids was evaluated as a potential low toxic variant for oil spill remediation. Further, the aggregation behavior of the individual as well as their binary mixtures was also evaluated by employing tensiometry technique. The half-lethal concentration, LC50on zebrafish (Danio rerio) of three choline based ionic liquids showed that the studied ionic liquids (ILs) fall in the range of “practically nontoxic” ( 100-1000 mg L-1).Various micellar properties showed that …
The Effect Of Precursor Design And Processing On The Semi-Crystalline Morphologies Of Polyacrylonitrile-Based Carbon Fiber,
2019
University of Southern Mississippi
The Effect Of Precursor Design And Processing On The Semi-Crystalline Morphologies Of Polyacrylonitrile-Based Carbon Fiber, Katelyn Cordell
Dissertations
Basic research to control the morphology of polyacrylonitrile (PAN)-based carbon fiber is crucial for next generation composites as it determines their mechanical properties and final use. Poor molecular design of PAN-based precursors and fiber processing causes morphological defects and mechanical limitations.1,2 This research focused on utilizing the controlled polymerization technique, reversible addition-fragmentation chain transfer (RAFT), of novel acrylamide comonomers to afford well-defined precursors with precisely controlled molecular design. This controlled RAFT technique improved the overall precursor graphitic structure as evident by the increased extent of stabilization and reduced activation energy as compared to precursors prepared by traditional free radical …
Beneficial Mutations For Carotenoid Production Identified From Laboratory-Evolved Saccharomyces Cerevisiae,
2019
Texas A&M University
Beneficial Mutations For Carotenoid Production Identified From Laboratory-Evolved Saccharomyces Cerevisiae, Avinash Godara, Maria Alejandra Gomez Rodriguez, Joshua Weatherston, George Peabody, Hung-Jen Wu, Katy Kao
Faculty Publications
Adaptive laboratory evolution (ALE) is a powerful tool used to increase strain fitness in the presence of environmental stressors. If production and strain fitness can be coupled, ALE can be used to increase product formation. In earlier work, carotenoids hyperproducing mutants were obtained using an ALE strategy. Here, de novo mutations were identified in hyperproducers, and reconstructed mutants were explored to determine the exact impact of each mutation on production and tolerance. A single mutation in YMRCTy1-3 conferred increased carotenoid production, and when combined with other beneficial mutations led to further increased β-carotene production. Findings also suggest that the ALE …
Integrating The Three E’S In Wastewater Treatment,
2019
Rowan University
Integrating The Three E’S In Wastewater Treatment, Kirti Maheshkumar Yenkie
Henry M. Rowan College of Engineering Departmental Research
Water is often the most mispriced and misused component in domestic, industrial and agricultural sectors. The rise in world population and industrialization in developing nations has tremendously increased the demand for water and has resulted in the generation of wastewater which is contaminated with dangerous pollutants and unknown contaminants. Furthermore, if the wastewater is not treated properly the toxic pollutants will leach back into the ground ultimately contaminating the groundwater resources. Thus, wastewater treatment, reuse, and safe disposal have become crucial for sustainable existence. In this review, the different aspects involved in designing efficient and sustainable wastewater treatment systems such …
Bicontinuous Interfacially Jammed Emulsion Gels (Bijels) As Media For Enabling Enzymatic Reactive Separation Of A Highly Water Insoluble Substrate,
2019
Pohang University of Science and Technology
Bicontinuous Interfacially Jammed Emulsion Gels (Bijels) As Media For Enabling Enzymatic Reactive Separation Of A Highly Water Insoluble Substrate, Sanghak Cha, Hyun Lim, Martin Haase, Kathleen Stebe, Gyoo Jung, Daeyeon Lee
Henry M. Rowan College of Engineering Departmental Research
Although enzymes are efficient catalysts capable of converting various substrates into desired products with high specificity under mild conditions, their effectiveness as catalysts is substantially reduced when substrates are poorly water-soluble. In this study, to expedite the enzymatic conversion of a hydrophobic substrate, we use a bicontinuous interfacially jammed emulsion gel (bijel) which provides large interfacial area between two immiscible liquids: oil and water. Using lipase-catalyzed hydrolysis of tributyrin as a model reaction in a batch mode, we show that bijels can be used as media to enable enzymatic reaction. The bijel system gives a four-fold increase in the initial …
Non-Invasive Detection And Assessment Of Coronary Stenosis From Blood Mean Residence Times.,
2019
University of Louisville
Non-Invasive Detection And Assessment Of Coronary Stenosis From Blood Mean Residence Times., Javad Hashemi
Electronic Theses and Dissertations
Coronary artery stenosis is an abnormal narrowing of a coronary artery caused by an atherosclerotic lesion that reduces lumen space. Fractional flow reserve (FFR) is the gold standard method to determine the severity of coronary stenosis based on the determination of rest and hyperemic pressure fields, but requires an invasive medical procedure. Normal FFR is 1.0 and FFR RT, to account for varying volume and flow rate of individual segments. BloodRT was computed in 100 patients who had undergone the pressure-wire FFR procedure, and a threshold for BloodRT was determined to assess the physiological significance of a stenosis, …
Development Of A Comsol Microdialysis Model, Towards Creation Of Microdialysis On A Chip With Improved Geometries And Recovery,
2019
University of Arkansas, Fayetteville
Development Of A Comsol Microdialysis Model, Towards Creation Of Microdialysis On A Chip With Improved Geometries And Recovery, Patrick Pysz
Graduate Theses and Dissertations
Microdialysis (µD) sampling is a diffusion-limited sampling method that has been widely used in different biomedical fields for greater than 35 years. Device calibration for in vivo studies is difficult for current non-steady state analytes of interest correlated with both inflammatory response and microbial signaling molecules (QS); which exist in low ng/mL to pg/mL with molecular weights over a wide range of 170 Da to 70 kDa. The primary performance metric, relative recovery (RR), relating the collected sample to the extracellular space concentration varies from 10% to 60% per analyte even under controlled bench-top conditions. Innovations in microdialysis device design …
Functional Importance Of Lipin Phosphorylation,
2019
University of Arkansas, Fayetteville
Functional Importance Of Lipin Phosphorylation, Stephanie Elizabeth Hood
Graduate Theses and Dissertations
Highly conserved throughout evolution, lipins are dual functioning proteins found from yeast to humans. Functioning in the cytoplasm as phosphatidate phosphatase enzymes (PAP), lipins produce diacylglycerol that serves as a precursor for neutral fats and membrane phospholipids. Alternatively, nuclear lipins are responsible for the regulation of metabolic genes. Interestingly, both the mammalian lipin 1 paralog and the single Drosophila Lipin ortholog are highly phosphorylated proteins. Target of rapamycin (TOR) has previously been identified as one of the kinases that controls the subcellular localization of both lipin 1 and Drosophila Lipin. However, other serine and threonine kinases are predicted to be …
Polyball: A New Adsorbent For The Efficient Removal Of Endotoxin From Biopharmaceuticals,
2019
Missouri University of Science and Technology
Polyball: A New Adsorbent For The Efficient Removal Of Endotoxin From Biopharmaceuticals, Sidharth Razdan, Jee-Ching Wang, Sutapa Barua
Chemical and Biochemical Engineering Faculty Research & Creative Works
The presence of endotoxin, also known as lipopolysaccharides (LPS), as a side product appears to be a major drawback for the production of certain biomolecules that are essential for research, pharmaceutical, and industrial applications. In the biotechnology industry, gram-negative bacteria (e.g., Escherichia coli ) are widely used to produce recombinant products such as proteins, plasmid DNAs and vaccines. These products are contaminated with LPS, which may cause side effects when administered to animals or humans. Purification of LPS often suffers from product loss. For this reason, special attention must be paid when purifying proteins aiming a product as free as …
Application Of Artificial Neural Networks In The Drilling Processes: Can Equivalent Circulation Density Be Estimated Prior To Drilling?,
2019
Missouri University of Science and Technology
Application Of Artificial Neural Networks In The Drilling Processes: Can Equivalent Circulation Density Be Estimated Prior To Drilling?, Husam Hasan Alkinani, Abo Taleb Al-Hameedi, Shari Dunn-Norman, David Lian
Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works
As the drilling environment became more challenging nowadays, managing equivalent circulating density (ECD) is a key factor to minimize non-productive time (NPT) due to many drilling obstacles such as stuck pipe, formation fracturing, and lost circulation. The goal of this work was to predict ECD prior to drilling by using artificial neural network (ANN). Once ECD is recognized, the crucial drilling variables impact ECD can be modified to control ECD within the acceptable ranges. Data from over 2000 wells collected worldwide were used in this study to create an ANN to predict ECD prior to drilling. Into training, validation, and …
Silver-Based Microbial Check Valve For Spacecraft Potable Water Systems,
2019
University of Arkansas, Fayetteville
Silver-Based Microbial Check Valve For Spacecraft Potable Water Systems, Tanner Burns
Chemical Engineering Undergraduate Honors Theses
As human space exploration increases, the development of a more efficient potable water treatment system suited for spacecraft becomes crucial. This Waste-management Education Research Consortium (WERC) challenge was designed to explore the viability of microbial control through the utilization of silver ions as a biocide for possible integration into the Tranquility Node 3 water purification system aboard the International Space Station (ISS). Current systems using iodine risk causing hyperthyroidism from overexposure; however, silver can be safely ingested without this side effect. After researching silver delivery methods including electrochemical ion production, controlled release, or a combination of the two, our team …
Multi-Scale Assessment Of Binding Geometries And Energetics Of Aqueous Phase Reforming Of Glycerol And Methanol: Towards Realistic, Accurate, And Computationally Tractable Strategies,
2019
Clemson University
Multi-Scale Assessment Of Binding Geometries And Energetics Of Aqueous Phase Reforming Of Glycerol And Methanol: Towards Realistic, Accurate, And Computationally Tractable Strategies, Tianjun Xie
All Dissertations
No abstract provided.
A Characterization Of Different Alkali Chemical Agents For Alkaline Flooding Enhanced Oil Recovery Operations: An Experimental Investigation,
2019
Missouri University of Science and Technology
A Characterization Of Different Alkali Chemical Agents For Alkaline Flooding Enhanced Oil Recovery Operations: An Experimental Investigation, Sherif Fakher, Hesham Abdelaal, Youssef Elgahawy, Abdulmohsin Imqam
Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works
Alkaline injection is a chemical enhanced oil recovery method that is used to increase oil recovery by reacting with the crude oil and creating an in situ surfactant. Many chemical agents can be used as an alkali during injection all of which have several advantages and disadvantages. This research focuses on the innate properties of three alkali agents and their ability to alter pH and temperature downhole. Alkali solutions were prepared with five different concentrations including 0.2, 1, 2, 3, and 4 wt%. The impact of varying the alkali concentration, monovalent cations manifested in sodium chloride, and divalent cations manifested …
Feasibility Analysis Of Adipic Acid Production,
2019
University of Nebraska-Lincoln
Feasibility Analysis Of Adipic Acid Production, Serpil Unlu
Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research
Adipic acid is an essential intermediate chemical feedstock for the production of nylon-6,6; hence it is valuable from an industrial perspective. Currently, commercial adipic acid production includes a combination of two stages. The first stage produces a mixture of cyclohexanone and cyclohexanol called ‘’KA oil” derived from cyclohexane. In the second stage, KA oil is reacted with nitric acid to produce adipic acid. The second stage generates excess N2O emission, which is considered as 310 times more potent than CO2. Renewable feedstocks that can be converted to value-added chemicals offer significant potential for the necessary transition …
Stabilization Of Bimodal Colloidal Systems Via Nanoparticle Haloing In Microgravity.,
2019
University of Louisville
Stabilization Of Bimodal Colloidal Systems Via Nanoparticle Haloing In Microgravity., Luke Hawtrey
Electronic Theses and Dissertations
Colloidal suspensions typically contain a multi-phase system of solid particles suspended in a liquid medium. Colloids are widely used in industrial applications such as inks, paints, motor oils, foods, cosmetics, and many more. Colloidal systems are typically formed by the interaction of the attractive van der Waals forces and one or more repulsive forces. These repulsive forces include electrostatic repulsion, steric hindrance, and nanoparticle haloing. Nanoparticle Haloing (NPH) is a phenomenon discovered in 2001 as a viable method to stabilize colloidal systems of uncharged silica microparticles using highly charged zirconia nanoparticles. For this thesis the effects of NPH were tested …
Vastly Extended Drug Release From Poly(Pro-17Β-Estradiol) Materials Facilitates In Vitro Neurotrophism And Neuroprotection,
2019
Missouri University of Science and Technology
Vastly Extended Drug Release From Poly(Pro-17Β-Estradiol) Materials Facilitates In Vitro Neurotrophism And Neuroprotection, Anthony R. D'Amato, Devan L. Puhl, Samuel A.T. Ellman, Bailey Balouch, Ryan J. Gilbert, Edmund F. Palermo
Chemical and Biochemical Engineering Faculty Research & Creative Works
Central nervous system (CNS) injuries persist for years, and currently there are no therapeutics that can address the complex injury cascade that develops over this timescale. 17β-estradiol (E2) has broad tropism within the CNS, targeting and inducing beneficial phenotypic changes in myriad cells following injury. To address the unmet need for vastly prolonged E2 release, we report first-generation poly(pro-E2) biomaterial scaffolds that release E2 at nanomolar concentrations over the course of 1–10 years via slow hydrolysis in vitro. As a result of their finely tuned properties, these scaffolds demonstrate the ability to promote and guide neurite extension ex vivo and …
Interfacial Contact With Noble Metal - Noble Metal And Noble Metal - 2d Semiconductor Nanostructures Enhance Optical Activity,
2019
University of Arkansas, Fayetteville
Interfacial Contact With Noble Metal - Noble Metal And Noble Metal - 2d Semiconductor Nanostructures Enhance Optical Activity, Ricardo Raphael Lopez Romo
Graduate Theses and Dissertations
Noble metal nanoparticles and two-dimensional (2D) transition metal dichalcogenide (TMD) crystals offer unique optical and electronic properties that include strong exciton binding, spin-orbital coupling, and localized surface plasmon resonance. Controlling these properties at high spatiotemporal resolution can support emerging optoelectronic coupling and enhanced optical features. Excitation dynamics of these optical properties on physicochemically bonded mono- and few-layer TMD crystals with metal nanocrystals and two overlapping spherical metal nanocrystals were examined by concurrently (i) DDA simulations and (ii) far-field optical transmission UV-vis spectroscopic measurements. Initially, a novel and scalable method to unsettle van der Waals bonds in bulk TMDs to prepare …
Theoretical Investigations Of The Electronic, Magnetic, And Thermoelectric Properties Of Transition-Metal Based Compounds,
2019
University of Arkansas, Fayetteville
Theoretical Investigations Of The Electronic, Magnetic, And Thermoelectric Properties Of Transition-Metal Based Compounds, Haleoot Edaan Raad
Graduate Theses and Dissertations
The electronic, magnetic, and thermoelectric properties of transition-metal based compounds were investigated by using the density functional theory and Boltzmann transport formalism. It was found that the Co-based Heusler compounds and InSe monochalcogenide are among the materials that may be used for future thermoelectric devices. Furthermore, the investigation showed that the quaternary Heusler compounds, such as, CoFeYGe, where Y is Ti or Cr, are half-metallic ferromagnetic materials with full electron spin polarization. The lattice thermal conductivity (κL) was found to decrease for these alloys as the temperature increases. The present investigation indicated that the phonon optical modes have a major …
