Incorporating Genome Annotation In The Statistical Analysis Of Genomic And Epigenomic Tiling Array Data,
2010
Missouri University of Science and Technology
Incorporating Genome Annotation In The Statistical Analysis Of Genomic And Epigenomic Tiling Array Data, Gayla R. Olbricht
Mathematics and Statistics Faculty Research & Creative Works
"A wealth of information and technologies are currently available for the genomewide investigation of many types of biological phenomena. Genomic annotation databases provide information about the DNA sequence of a particular organism and give locations of different types of genomic elements, such as the exons and introns of genes. Microarrays are a powerful type of technology that make use of DNA sequence information to investigate different types of biological phenomena on a genome-wide level. Tiling arrays are a unique type of microarray that provide unbiased, highdensity coverage of a genomic region, making them well suited for many applications, such as …
The Beta Maxwell Distribution,
2010
Marshall University
The Beta Maxwell Distribution, Grace Ebunoluwa Amusan
Theses, Dissertations and Capstones
In this work we considered a general class of distributions gener- ated from the logit of the beta random variable. We looked at various works that have been done and discussed some of the results that were obtained. Special cases of this class include the beta-normal distribution, the beta-exponential distribution, the beta-Gumbell distribution, the beta-Weibull distribution, the beta-Pareto distribution and the beta-Rayleigh distribution. We looked at the probability distribution functions of each of these distributions and also look at some of their properties. Another special case of this family, a three-parameter beta-Maxwell distribution was dened and studied. Various properties of …
Periodic Solutions Of Neutral Delay Integral Equations Of Advanced Type,
2010
University of Dayton
Periodic Solutions Of Neutral Delay Integral Equations Of Advanced Type, Muhammad Islam, Nasrin Sultana, James Booth
Mathematics Faculty Publications
We study the existence of continuous periodic solutions of a neutral delay integral equation of advanced type. In the analysis we employ three fixed point theorems: Banach, Krasnosel'skii, and Krasnosel'skii-Schaefer. Krasnosel'skii-Schaefer fixed point theorem requires an a priori bound on all solutions. We employ a Liapunov type method to obtain such bound.
Principal Component Analysis And Biochemical Characterization Of Protein And
Starch Reveal Primary Targets For Improving Sorghum Grain,
2010
University of California - Berkeley
Principal Component Analysis And Biochemical Characterization Of Protein And Starch Reveal Primary Targets For Improving Sorghum Grain, Joshua H. Wong, D. B. Marx, Jeff D. Wilson, Bob B. Buchanan, Peggy G. Lemaux, Jeffrey F. Pedersen
Department of Statistics: Faculty Publications
Limited progress has been made on genetic improvement of the digestibility of sorghum grain because of variability among different varieties. In this study, we applied multiple techniques to assess digestibility of grain from 18 sorghum lines to identify major components responsible for variability. We also identified storage proteins and enzymes as potential targets for genetic modification to improve digestibility. Results from principal component analysis revealed that content of amylose and total starch, together with protein digestibility (PD), accounted for 94% of variation in digestibility. Control of amylose content is understood and manageable. Up-regulation of genes associated with starch accumulation is …
Reference Priors For Exponential Families
With Increasing Dimension,
2010
University of Nebraska-Lincoln
Reference Priors For Exponential Families With Increasing Dimension, Bertrand S. Clarke, Subhashis Ghosal
Department of Statistics: Faculty Publications
In this article, we establish the asymptotic normality of the posterior distribution for the natural parameter in an exponential family based on independent and identically distributed data. The mode of convergence is expected Kullback-Leibler distance and the number of parameters p is increasing with the sample size n. Using this, we give an asymptotic expansion of the Shannon mutual information valid when p = pn increases at a sufficiently slow rate. The second term in the asymptotic expansion is the largest term that depends on the prior and can be optimized to give Jeffreys’ prior as the reference prior in …
Desiderata For A Predictive Theory Of Statistics,
2010
University of Miami
Desiderata For A Predictive Theory Of Statistics, Bertrand Clarke
Department of Statistics: Faculty Publications
In many contexts the predictive validation of models or their associated prediction strategies is of greater importance than model identification which may be practically impossible. This is particularly so in fields involving complex or high dimensional data where model selection, or more generally predictor selection is the main focus of effort. This paper suggests a unified treatment for predictive analyses based on six 'desiderata'. These desiderata are an effort to clarify what criteria a good predictive theory of statistics should satisfy.
Mathematical Themes In Economics, Machine Learning, And Bioinformatics,
2010
Western Kentucky University
Mathematical Themes In Economics, Machine Learning, And Bioinformatics, Matt Bogard
Economics Faculty Publications
Graduate students in economics are often introduced to some very useful mathematical tools that many outside the discipline may not associate with training in economics. This essay looks at some of these tools and concepts, including constrained optimization, separating hyperplanes, supporting hyperplanes, and ‘duality.’ Applications of these tools are explored including topics from machine learning and bioinformatics.
Sustainable Agriculture Bibliography,
2010
Western Kentucky University
Sustainable Agriculture Bibliography, Matt Bogard
Agriculture Department Seminar Series
An annotated bibliography related to the sustainability of biotechnology and pharmaceutical technologies used in modern agriculture.
Item Order Effects On Attitude Measures,
2010
University of Denver
Item Order Effects On Attitude Measures, Pei-Hua Chen
Electronic Theses and Dissertations
The purpose of this dissertation was to examine the effects of altered item order on attitude measures for both computerized adaptive and conventional survey formats. Based on items modified from a dissertation/thesis completion survey (Green & Kluever, 1997) with three scales, three survey versions were generated with items ordered by difficulty as hard-to-easy (H-E), easy-to-hard (E-H), and five medium trait level items presented first followed by randomly ordered items (M-R) for conventional survey format. Significant differences in item difficulty and item discrimination were found for two of the three scales. Differences in scale reliability were detected for the procrastination and …
Using R,
2010
Western Kentucky University
Using R, Matt Bogard
Economics Faculty Publications
R is a statistical programming language with a command line interface that is becoming more and more popular every day. I have used R for data visualization, data mining/machine learning, as well as social network analysis. Initially embraced largely in academia, R is becoming the software of choice in various corporate settings.
Using Twitter To Demonstrate Basic Concepts From Network Analysis,
2010
Western Kentucky University
Using Twitter To Demonstrate Basic Concepts From Network Analysis, Matt Bogard
Economics Faculty Publications
Social network analysis focuses on finding patterns in interactions between people or entities. These patterns may be described in the form of a network. Network analysis in general has many applications including models of student integration and persistence, business to business supply chains, terrorist cells, or analysis of social media such as Facebook and Twitter. This presentation provides a reference for basic concepts from social network analysis with examples using tweets from Twitter.
Noncompliance With Public Health Service (Phs) Policy On Humane Care And Use Of Laboratory Animals: An Exploratory Analysis,
2010
The Humane Society of the United States
Noncompliance With Public Health Service (Phs) Policy On Humane Care And Use Of Laboratory Animals: An Exploratory Analysis, Leah M. Gomez, Kathleen Conlee, Martin Stephens
Laboratory Experiments Collection
The National Institutes of Health (NIH) is a major biomedical research-funding body in the United States. Approximately 40% of NIH-funded research involves experimentation on nonhuman animals (Monastersky, 2008). Institutions that conduct animal research with NIH funds must adhere to the Public Health Service (PHS) care and use standards of the Office of Laboratory Animal Welfare (OLAW, 2002a). Institutions deviating significantly from the PHS’s animal care and use standards must report these incidents to the NIH’s OLAW. This study is an exploratory analysis of all the significant deviations reported by animal-research facilities to OLAW during a 3-month period. The study identifies …
Gronwall-Ouiang-Type Integral Inequalities On Time Scales,
2010
Missouri University of Science and Technology
Gronwall-Ouiang-Type Integral Inequalities On Time Scales, Ailian Liu, Martin Bohner
Mathematics and Statistics Faculty Research & Creative Works
We present several Gronwall-OuIang-type integral inequalities on time scales. Firstly, an OuIang inequality on time scales is discussed. Then we extend the Gronwall-type inequalities to multiple integrals. Some special cases of our results contain continuous Gronwall-type inequalities and their discrete analogues. Several examples are included to illustrate our results at the end.
Weyl-Titchmarsh Theory For Hamiltonian Dynamic Systems,
2010
Missouri University of Science and Technology
Weyl-Titchmarsh Theory For Hamiltonian Dynamic Systems, Shurong Sun, Shaozhu Chen, Martin Bohner
Mathematics and Statistics Faculty Research & Creative Works
We establish the Weyl-Titchmarsh theory for singular linear Hamiltonian dynamic systems on a time scale T , which allows one to treat both continuous and discrete linear Hamiltonian systems as special cases for T= ℝ and T= ℤ within one theory and to explain the discrepancies between these two theories. This paper extends the Weyl-Titchmarsh theory and provides a foundation for studying spectral theory of Hamiltonian dynamic systems. These investigations are part of a larger program which includes the following: (i) M(λ) theory for singular Hamiltonian systems, (ii) on the spectrum of Hamiltonian systems, (iii) on boundary value problems for …
Ua56/1 Fact Book,
2010
Western Kentucky University
Ua56/1 Fact Book, Wku Institutional Research
WKU Administration Documents
Statistical and demographic profile of WKU.
Is Screening Cargo Containers For Smuggled Nuclear Threats Worthwhile?,
2010
Virginia Commonwealth University
Is Screening Cargo Containers For Smuggled Nuclear Threats Worthwhile?, Jason R. W. Merrick, Laura A. Mclay
Statistical Sciences and Operations Research Publications
In recent years, Customs and Border Protection (CBP) has installed radiation sensors to screen cargo containers entering theUnited States. They are concerned that terrorists could use containers to smuggle radiological material into the country and carry out attacks with dirty bombs or a nuclear device. Recent studies have questioned the value of improving this screening system with new sensor technology. The cost of delays caused by frequent false alarms outweighs any reduction in the probability of an attack in an expected cost analysis. We extend existing methodology in three ways to demonstrate how additional factors affect the value of screening …
Type Ii Robustness Of The Null Hypothesis Rho = 0 For Non-Normal Distributions,
2010
Wayne State University
Type Ii Robustness Of The Null Hypothesis Rho = 0 For Non-Normal Distributions, Stephanie Wren
Wayne State University Dissertations
Is the t test statistic for the Pearson Product Moment Correlation Coefficient robust to errors of the second kind? This investigation indirectly measured the effects of power through a type 2 error rate robustness study. The results were revealing.
Identification Of Neuroblastoma And Its Prognostic Markers Using Raman Spectroscopy,
2010
Wayne State University
Identification Of Neuroblastoma And Its Prognostic Markers Using Raman Spectroscopy, Rachel Kast
Wayne State University Dissertations
Introduction: Neuroblastoma is the most common cancer of infancy. It is one of several peripheral nervous system tumors, including ganglioneuroma, peripheral nerve sheath tumor, and pheochromocytoma. It is commonly situated on the adrenal gland. It displays similar histology to other small round blue cell tumors, including non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma. One method of judging neuroblastoma aggressiveness uses tumor histology factors, including mitosis-karyorrhexis index, Schwannian stromal development, degree of differentiation, and patient age. Tumor aggressiveness can also be judged based on the amplification of certain genes, including MYCN. Raman spectroscopy is a physics-based method which identifies the biochemical …
Traveling Wave Solutions For A Nonlocal Reaction-Diffusion Model Of Influenza A Drift,
2010
Wright State University - Main Campus
Traveling Wave Solutions For A Nonlocal Reaction-Diffusion Model Of Influenza A Drift, Joaquin Riviera, Yi Li
Mathematics and Statistics Faculty Publications
In this paper we discuss the existence of traveling wave solutions for a nonlocal reaction-diffusion model of Influenza A proposed in Lin et. al. (2003). The proof for the existence of the traveling wave takes advantage of the different time scales between the evolution of the disease and the progress of the disease in the population. Under this framework we are able to use the techniques from geometric singular perturbation theory to prove the existence of the traveling wave.
Confidence Intervals In Survival Analysis,
2010
Universiti Malaya
Confidence Intervals In Survival Analysis, Tan Shay Kee
Student Works (2010-2019)
In obtaining confidence interval for the survivor function using Greenwood’s formula and in performing log-rank test for comparing the survivor functions of two groups of individuals, only the information given by the first two moments of the relevant statistics are used. Presently we show that by incorporating the information given by the third and fourth moments of the statistics, the performance of the confidence interval and statistical test can be improved. When the survivor function can be described by the Weibull distribution, the knowledge regarding the survivor function can be obtained through the estimation of the Weibull scale and shape …
