Statistics and Probability Commons^™

An Analysis Of Postmastectomy Breast Reconstruction Due To Breast Cancer In Nevada And The United States From 2008-2013, Jenna Webb

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: In the United States, female breast cancer was the leading cause of new cancer cases from 2011-2015. Since the Women’s Health and Cancer Act of 1998 (WHCRA), the federal government mandates employee and private health insurance providers to cover breast reconstruction if they cover mastectomies. Postmastectomy breast reconstruction (PBR) rates increased after the WHCRA, but these rates have remained relatively low throughout recent years. Objective: The objective of this study was to determine factors associated with women having PBR due to breast cancer in Nevada and the United States from 2008 to 2013. Methods: Using two HCUP database, NIS …

Contributions To Mcmc Methods In Constrained Domains With Applications To Neuroimaging, Sharang Chaudhry

UNLV Theses, Dissertations, Professional Papers, and Capstones

Markov chain Monte Carlo (MCMC) methods form a rich class of computational techniques that help its user ascertain samples from target distributions when direct sampling is not possible or when their closed forms are intractable. Over the years, MCMC methods have been used in innumerable situations due to their flexibility and generalizability, even in situations involving nonlinear and/or highly parametrized models. In this dissertation, two major works relating to MCMC methods are presented.

The first involves the development of a method to identify the number and directions of nerve fibers using diffusion-weighted MRI measurements. For this, the biological problem is …

Effects Of Perioperative Hyperglycemia In Patients With Diabetes Compared To Patients Without Diabetes: A Retrospective Study Of Treatment And Outcomes, Matthew Anderson

Capstone Experience: Master of Public Health

The main goal of this project was to examine the differences in perioperative hyperglycemia treatment received by patients with a diagnosis of diabetes mellitus (DM) and patients without a diagnosis of diabetes (NDM); and how these treatment differences can affect the length of hospital stay. Studies have revealed that, when comparing DM and NDM patients with the same degree of perioperative hyperglycemia, NDM patients suffer worse outcomes. It has been suggested in previous research that this may be because NDM patients receive treatment that does not measure up to the standard of care treatment that DM patients receive. In this …

Advanced Statistics In Arkansas Sports Reporting, Andrew Lee Epperson

Graduate Theses and Dissertations

This study seeks to analyze how Arkansas’ sports journalists are adapting to the recent surge in available advanced statistics that are being used by certain national news organizations. Using in-depth qualitative research that includes in-depth interviews with a number of individuals in the print, broadcast, and athletics side of sports coverage, we discover how journalists and coaches use these next-generation analytics, what they fundamentally mean for the evolution of each respective path, and why so few Arkansas reporters and writers use them at the time of this paper’s defense. We see how budgets and deadlines restrict the use of these …

Comparing Elo, Glicko, Irt, And Bayesian Irt Statistical Models For Educational And Gaming Data, Breanna Morrison

Graduate Theses and Dissertations

Statistical models used for estimating skill or ability levels often vary by field, however their underlying mathematical models can be very similar. Differences in the underlying models can be due to the need to accommodate data with different underlying formats and structure. As the models from varying fields increase in complexity, their ability to be applied to different types of data may have the ability to increase. Models that are applied to educational or psychological data have advanced to accommodate a wide range of data formats, including increased estimation accuracy with sparsely populated data matrices. Conversely, the field of online …

Is Animal-Based Biomedical Research Being Used In Its Original Context?, Constança Carvalho, Daniel Alves, Andrew Knight, Luís Vicente

Validation of Animal Experimentation Collection

No abstract provided.

Critically Evaluating Animal Research, Andrew Knight

Validation of Animal Experimentation Collection

No abstract provided.

Deep Learning, Medical Physics And Cargo Cult Science., Miguel Romero Phd, Gilmer Valdes Phd, Timothy Solberg Phd, Yannet Interian Phd

Creative Activity and Research Day - CARD

Deep learning algorithms have become widely popular, with considerable success in fields where datasets have hundreds of thousands or million points. As deep learning is increasingly applied to the fields of medical physics and radiation oncology, a reasonable question follows: are these techniques the best approach, given the unique conditions in our field? In this study, we investigate the dependence of dataset size on the performance of deep learning algorithms compared with more traditional radiomics-based methods.

Deep Neural Network Architectures For Music Genre Classification, Kai Middlebrook, Shyam Sudhakaran, Kunal Sonar, David Guy Brizan

Creative Activity and Research Day - CARD

With the recent advancements in technology, many tasks in fields such as computer vision, natural language processing, and signal processing have been solved using deep learning architectures. In the audio domain, these architectures have been used to learn musical features of songs to predict: moods, genres, and instruments. In the case of genre classification, deep learning models were applied to popular datasets--which are explicitly chosen to represent their genres--and achieved state-of-the-art results. However, these results have not been reproduced on less refined datasets. To this end, we introduce an un-curated dataset which contains genre labels and 30-second audio previews for …

Variance Heterogeneity In Psychological Research: A Monte Carlo Study Of The Consequences For Meta-Analysis, Bruce E. Blaine

Statistics Faculty/Staff Publications

Variance heterogeneity is common in psychological research. Surveys of psychological research show that variance ratios (VRs) in two-group studies average around 2.5, with a substantial minority of studies having much higher VRs. Research has established that variance heterogeneity disturbs Type I error rates of parametric tests in primary research. Fixed-effects meta-analysis is a common statistical method in psychology for synthesizing primary research, and plays an important role in cumulative science and evidence-based practice. Little is known about the consequences of variance heterogeneity for meta-analytic estimates. The present research reports a Monte Carlo study in which the results of k = …

A Gene-Based Recessive Diplotype Exome Scan Discovers Fgf6, A Novel Hepcidin-Regulating Iron-Metabolism Gene, Shicheng Guo, Shuai Jiang, Narendranath Epperla, Yanyun Ma, Mehdi Maadooliat, Zhan Ye, Brent Olson, Minghua Wang, Terrie Kitchner, Jeffrey Joyce, Peng An, Fudi Wang, Robert Strenn, Joseph J. Mazza, Jennifer K. Meece, Wenyu Wu, Li Jin, Judith A. Smith, Jiucan Wang, Steven J. Schrodi

Mathematical and Statistical Science Faculty Research and Publications

Standard analyses applied to genome-wide association data are well designed to detect additive effects of moderate strength. However, the power for standard genome-wide association study (GWAS) analyses to identify effects from recessive diplotypes is not typically high. We proposed and conducted a gene-based compound heterozygosity test to reveal additional genes underlying complex diseases. With this approach applied to iron overload, a strong association signal was identified between the fibroblast growth factor–encoding gene, FGF6, and hemochromatosis in the central Wisconsin population. Functional validation showed that fibroblast growth factor 6 protein (FGF-6) regulates iron homeostasis and induces transcriptional regulation of hepcidin. …

The Andersen Likelihood Ratio Test With A Random Split Criterion Lacks Power, Georg Krammer

Journal of Modern Applied Statistical Methods

The Andersen LRT uses sample characteristics as split criteria to evaluate Rasch model fit, or theory driven hypothesis testing for a test. The power and Type I error of a random split criterion was evaluated with a simulation study. Results consistently show a random split criterion lacks power.

Deep Embedding Kernel, Linh Le

Doctor of Data Science and Analytics Dissertations

Kernel methods and deep learning are two major branches of machine learning that have achieved numerous successes in both analytics and artificial intelligence. While having their own unique characteristics, both branches work through mapping data to a feature space that is supposedly more favorable towards the given task. This dissertation addresses the strengths and weaknesses of each mapping method through combining them and forming a family of novel deep architectures that center around the Deep Embedding Kernel (DEK). In short, DEK is a realization of a kernel function through a newly deep architecture. The mapping in DEK is both implicit …

Weighted Version Of Generalized Inverse Weibull Distribution, Sofi Mudiasir, S. P. Ahmad

Journal of Modern Applied Statistical Methods

Weighted distributions are used in many fields, such as medicine, ecology, and reliability. A weighted version of the generalized inverse Weibull distribution, known as weighted generalized inverse Weibull distribution (WGIWD), is proposed. Basic properties including mode, moments, moment generating function, skewness, kurtosis, and Shannon’s entropy are studied. The usefulness of the new model was demonstrated by applying it to a real-life data set. The WGIWD fits better than its submodels, such as length biased generalized inverse Weibull (LGIW), generalized inverse Weibull (GIW), inverse Weibull (IW) and inverse exponential (IE) distributions.

Calibration Of Measurements, Edward Kroc, Bruno D. Zumbo

Journal of Modern Applied Statistical Methods

Traditional notions of measurement error typically rely on a strong mean-zero assumption on the expectation of the errors conditional on an unobservable “true score” (classical measurement error) or on the data themselves (Berkson measurement error). Weakly calibrated measurements for an unobservable true quantity are defined based on a weaker mean-zero assumption, giving rise to a measurement model of differential error. Applications show it retains many attractive features of estimation and inference when performing a naive data analysis (i.e. when performing an analysis on the error-prone measurements themselves), and other interesting properties not present in the classical or Berkson cases. Applied …

Assessing The Efficacy Of Home-Based Renal Care Using Propensity Scores, Eunice Choi

Mathematics & Statistics ETDs

This study investigated the efficacy of Home-Based Renal Care (HBRC) in diabetic Zuni Indians with Chronic Kidney Disease (CKD) in New Mexico using propensity scores. Home based intervention as opposed to standard clinical care is a pragmatic treatment approach that incorporates the preference of population in hopes of addressing a cultural barrier to healthcare in this high risk population. This study uses a logistic regression model and a linear regression model to estimate the average effect of HBRC on increasing the likelihood of participants taking a more active role in the management of their chronic condition compared to the control …

Estimation Of Mean With Two-Parameter Ratio-Product-Ratio Estimator In Double Sampling Using Ancillary Information Under Non-Response, Surya K. Pal, Housila P. Singh

Journal of Modern Applied Statistical Methods

Ratio-product-ratio estimators with two parameters in double sampling under non-response are considered along with their properties. Practical conditions are obtained in which the suggested estimators are more proficient than other existing estimators. An example is given.

Capturing Heterogeneity Of Covariate Effects In Hidden Subpopulations In The Presence Of Censoring And Large Number Of Covariates, Farhad Shokoohi, Abbas Khalili, Masoud Asgharian, Shili Lin

Mathematical Sciences Faculty Research

The advent of modern technology has led to a surge of high-dimensional data in biology and health sciences such as genomics, epigenomics and medicine. The high-grade serous ovarian cancer (HGS-OvCa) data reported by The Cancer Genome Atlas (TCGA) Research Network is one example. The TCGA and other research groups have analyzed several aspects of these data. Here we study the relationship between Disease Free Time (DFT) after surgery among ovarian cancer patients and their DNA methylation profiles of genomic features. Such studies pose additional challenges beyond the typical big data problem due to population substructure and censoring. Despite the availability …

A More Powerful Unconditional Exact Test Of Homogeneity For 2 × C Contingency Table Analysis, Louis Ehwerhemuepha, Heng Sok, Cyril Rakovski

Mathematics, Physics, and Computer Science Faculty Articles and Research

The classical unconditional exact p-value test can be used to compare two multinomial distributions with small samples. This general hypothesis requires parameter estimation under the null which makes the test severely conservative. Similar property has been observed for Fisher's exact test with Barnard and Boschloo providing distinct adjustments that produce more powerful testing approaches. In this study, we develop a novel adjustment for the conservativeness of the unconditional multinomial exact p-value test that produces nominal type I error rate and increased power in comparison to all alternative approaches. We used a large simulation study to empirically estimate the …

Essays On Time Series And Machine Learning Techniques For Risk Management, Michael Kotarinos

USF Tampa Graduate Theses and Dissertations

The Capital Asset Pricing Model combined with the Sharpe ratio is a standard method for choosing assets for selection in a portfolio. However, this method has many structural issues and was designed for a time when high dimensional computing was in its infancy. An alternative to these methods using a mix of Multi-Level Time Series Clustering, the MACBETH algorithm and traditional time series techniques was constructed that minimized data loss and allow for customized portfolio construction for investors with different risk profiles and specialized investment needs. It was shown that these methods are adaptable to cloud computing environments and allow …