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A Bayesian Regression Tree Approach To Identify The Effect Of Nanoparticles Properties On Toxicity Profiles, Cecile Low-Kam, Haiyuan Zhang, Zhaoxia Ji, Tian Xia, Jeffrey I. Zinc, Andre Nel, Donatello Telesca 2013 UCLA Biostatistics - CNSI

A Bayesian Regression Tree Approach To Identify The Effect Of Nanoparticles Properties On Toxicity Profiles, Cecile Low-Kam, Haiyuan Zhang, Zhaoxia Ji, Tian Xia, Jeffrey I. Zinc, Andre Nel, Donatello Telesca

COBRA Preprint Series

We introduce a Bayesian multiple regression tree model to characterize relationships between physico-chemical properties of nanoparticles and their in-vitro toxicity over multiple doses and times of exposure. Unlike conventional models that rely on data summaries, our model solves the low sample size issue and avoids arbitrary loss of information by combining all measurements from a general exposure experiment across doses, times of exposure, and replicates. The proposed technique integrates Bayesian trees for modeling threshold effects and interactions, and penalized B-splines for dose and time-response surfaces smoothing. The resulting posterior distribution is sampled via a Markov Chain Monte Carlo algorithm. This …


“Seeing” The Elephant: Assessing The Impact Of Library-Composition Program Collaboration On First-Year Student Learning, Erin E. Rinto 2013 University of Nevada, Las Vegas

“Seeing” The Elephant: Assessing The Impact Of Library-Composition Program Collaboration On First-Year Student Learning, Erin E. Rinto

Library Faculty Presentations

Though university libraries and composition programs have historically collaborative relationships, these partnerships can take a variety of formats, including single course period library sessions, teaching-the-teachers, and librarian-driven assignment models. A hybrid of these collaborative approaches was implemented Fall 2012 at UNLV in an effort to provide first-year composition students with a more systematic information literacy experience in the required ENG 102 course. A two-pronged assessment method was used to evaluate the impact of the collaboration for both first-year student learning as well as to implement programmatic change.


Epistemology And Synthesis: Instrumental Neutron Activation Analysis And The Caddo Tradition, Robert Z. Selden Jr. 2013 Heritage Research Center, Stephen F. Austin State University

Epistemology And Synthesis: Instrumental Neutron Activation Analysis And The Caddo Tradition, Robert Z. Selden Jr.

CRHR: Archaeology

The statistical groupings illustrated herein represent the current iteration of Caddo INAA compositional groups based upon the chemical composition of archaeologically-recovered ceramics. For some time, a number of Caddo archaeologists have thought these results to be lacking. This poster symbolizes the first step toward a new interpretation of chemical composition groups, and the initial instancce within which GIS has been employed as an analytical tool.


Consilience: Radiocarbon, Instrumental Neutron Activation Analysis, And Litigation In The Ancestral Caddo Region, Robert Z. Selden Jr. 2013 Heritage Research Center, Stephen F. Austin State University

Consilience: Radiocarbon, Instrumental Neutron Activation Analysis, And Litigation In The Ancestral Caddo Region, Robert Z. Selden Jr.

CRHR: Archaeology

Through the creation and analysis of databases for radiocarbon, instrumental neutron activation analysis (INAA), and law, macro-level trends are exposed that form the framework of a broader research program aimed at advancing ideas of craft specialization and archaeological theory in the ancestral Caddo region of Southwest Arkansas, Northwest Louisiana, Northeast Texas, and Southeast Oklahoma. The findings of this investigation illustrate the research potential that remains buried within the context of cultural resource management (CRM) reports and legal databases (Westlaw and LexisNexis) that is awaiting consumption within regional research designs aimed at exploring the nuances and trends that appear through synthetic …


James-Stein Type Compound Estimation Of Multiple Mean Response Functions And Their Derivatives, Limin Feng 2013 University of Kentucky

James-Stein Type Compound Estimation Of Multiple Mean Response Functions And Their Derivatives, Limin Feng

Theses and Dissertations--Statistics

Charnigo and Srinivasan originally developed compound estimators to nonparametrically estimate mean response functions and their derivatives simultaneously when there is one response variable and one covariate. The compound estimator maintains self consistency and almost optimal convergence rate. This dissertation studies, in part, compound estimation with multiple responses and/or covariates. An empirical comparison of compound estimation, local regression and spline smoothing is included, and near optimal convergence rates are established in the presence of multiple covariates.

James and Stein proposed an estimator of the mean vector of a p dimensional multivariate normal distribution, which produces a smaller risk than the maximum …


Mapping And Decomposing Scale-Dependent Soil Moisture Variability Within An Inner Bluegrass Landscape, Carla Landrum 2013 University of Kentucky

Mapping And Decomposing Scale-Dependent Soil Moisture Variability Within An Inner Bluegrass Landscape, Carla Landrum

Theses and Dissertations--Plant and Soil Sciences

There is a shared desire among public and private sectors to make more reliable predictions, accurate mapping, and appropriate scaling of soil moisture and associated parameters across landscapes. A discrepancy often exists between the scale at which soil hydrologic properties are measured and the scale at which they are modeled for management purposes. Moreover, little is known about the relative importance of hydrologic modeling parameters as soil moisture fluctuates with time. More research is needed to establish which observation scales in space and time are optimal for managing soil moisture variation over large spatial extents and how these scales are …


Multiscale Analysis Of Factors That Affect The Distribution Of Sharks Throughout The Northern Gulf Of Mexico, J. Marcus Drymon, Laure Carassou, Sean P. Powers, Mark Grace, John Dindo, Brian Dzwonkowski 2013 University of South Alabama

Multiscale Analysis Of Factors That Affect The Distribution Of Sharks Throughout The Northern Gulf Of Mexico, J. Marcus Drymon, Laure Carassou, Sean P. Powers, Mark Grace, John Dindo, Brian Dzwonkowski

University Faculty and Staff Publications

Identification of the spatial scale at which marine communities are organized is critical to proper management, yet this is particularly difficult to determine for highly migratory species like sharks. We used shark catch data collected during 2006–09 from fishery- independent bottom-longline surveys, as well as biotic and abiotic explanatory data to identify the factors that affect the distribution of coastal sharks at 2 spatial scales in the northern Gulf of Mexico. Centered principal component analyses (PCAs) were used to visualize the patterns that characterize shark distributions at small (Alabama and Mississippi coast) and large (northern Gulf of Mexico) spatial scales. …


Quest For Continuous Improvement: Gathering Feedback And Data Through Multiple Methods To Evaluate And Improve A Library’S Discovery Tool, Jeanne M. Brown 2012 University of Nevada, Las Vegas

Quest For Continuous Improvement: Gathering Feedback And Data Through Multiple Methods To Evaluate And Improve A Library’S Discovery Tool, Jeanne M. Brown

Library Faculty Presentations

Summon at UNLV

  • Implemented fall 2011: a web-scale discovery tool
  • Expectations for Summon
  • Continuous Summon Improvement (CSI)Group

The environment

  • User changes
  • Library changes
  • Vendor changes
  • Product changes
  • Complex information environment
  • Change + complexity = need to assess using multiple streams of feedback


Spectral Cross Correlation As A Supervised Approach For The Analysis Of Complex Raman Datasets: The Case Of Nanoparticles In Biological Cells, Mark Keating, Franck Bonnier, Hugh Byrne 2012 Technological University Dublin

Spectral Cross Correlation As A Supervised Approach For The Analysis Of Complex Raman Datasets: The Case Of Nanoparticles In Biological Cells, Mark Keating, Franck Bonnier, Hugh Byrne

Articles

Spectral Cross-correlation is introduced as a methodology to identify the presence and subcellular distribution of nanoparticles in cells. Raman microscopy is employed to spectroscopically image biological cells previously exposed to polystyrene nanoparticles, as a model for the study of nano-bio interactions. The limitations of previously deployed strategies of K-means clustering analysis and principal component analysis are discussed and a novel methodology of Spectral Cross Correlation Analysis is introduced and compared with the performance of Classical Least Squares Analysis, in both unsupervised and supervised modes. The previous study demonstrated the feasibility of using Raman spectroscopy to map cells and identify polystyrene …


Reconstructability Of Epistatic Functions, Martin Zwick, Joe Fusion, Beth Wilmot 2012 Portland State University

Reconstructability Of Epistatic Functions, Martin Zwick, Joe Fusion, Beth Wilmot

Complex Systems Faculty Publications and Presentations

Background: Reconstructability Analysis (RA) has been used to detect epistasis in genomic data; in that work, even the simplest RA models (variable-based models without loops) gave performance superior to two other methods. A follow-on theoretical study showed that RA also offers higher-resolution models, namely variable-based models with loops and state-based models, likely to be even more effective in modeling epistasis, and also described several mathematical approaches to classifying types of epistasis.

Methods: The present paper extends this second study by discussing a non-standard use of RA: the analysis of epistasis in quantitative as opposed to nominal variables; such quantitative variables …


Learning Outcomes For Library Student Workers, Jeanne M. Brown 2012 University of Nevada, Las Vegas

Learning Outcomes For Library Student Workers, Jeanne M. Brown

Library Faculty Presentations

Our Dean of Libraries, Patty Iannuzzi has indicated that employment in the library can and should offer value to the student worker beyond convenience and flexible hours. In her words, "The libraries are well positioned to add value to our students' work experience in ways that can contribute to their academic success. As one of the largest employers of student workers on campus, we owe this to our students. As an organization, we want to clearly send a message that we care about them as students -- not just our employees." In Spring 2011, the Libraries partnered with Campus Life …


A Comparison Of Individual Versus Community Influences On Youth Smoking Behaviours: A Cross-Sectional Observational Study, Anna M. Adachi-Mejia, Heather A. Carlos, Ethan M. Berke, Susanne E. Tanski, James Sargent 2012 Dartmouth College

A Comparison Of Individual Versus Community Influences On Youth Smoking Behaviours: A Cross-Sectional Observational Study, Anna M. Adachi-Mejia, Heather A. Carlos, Ethan M. Berke, Susanne E. Tanski, James Sargent

Dartmouth Scholarship

Objectives: To compare individual with community risk factors for adolescent smoking. Design: A cross-sectional observational study with multivariate analysis.Setting: National telephone survey.Participants: 3646 US adolescents aged 13–18 years in 2007 recruited through a random digit-dial survey.


Blunt Impact Performance Evaluation Of Helmet Lining Systems For Military And Recreational Use, Jaclyn Siniora, Ryan Taylor, Darren Suey 2012 California Polytechnic State University - San Luis Obispo

Blunt Impact Performance Evaluation Of Helmet Lining Systems For Military And Recreational Use, Jaclyn Siniora, Ryan Taylor, Darren Suey

Industrial Technology and Packaging

With the increasing problem in collegiate athletes experiencing injuries to the brain, different helmet liners where put to the test to see which liner provided athletes the greatest protection under specific conditions.

This senior project evaluates five different liners in football helmets. Each of the helmet liners were tested at three different temperatures: hot, cold, and ambient. Each helmet had seven different impact locations which were put to the test. The project was designed to be used to test ACH military combat liners as well. Due to shipping bottle necks the ACH combat liners have been left to future Cal …


Analysis Of Dietary Patterns Over Freshman Year Of College, Chelsea Lofland 2012 California Polytechnic State University, San Luis Obispo

Analysis Of Dietary Patterns Over Freshman Year Of College, Chelsea Lofland

Statistics

This analysis is an investigation of changes in Cal Poly students’ eating habits over freshman year. The motivation behind this was an interest in college students’ lifestyles; college is the first time most students live on their own and it can be an important maturation period. College is stressful, exciting, liberating, and terrifying all at the same time. This distinctive life experience, along with my desire to handle big and messy data, led me to this research question.

The response variable analyzed was food consumption and the explanatory variables were: sex, race, quarter, food group, stress, exercise, BMI, sleep quality …


Interactive Concept To Aid In Understanding Dimensional Analysis, Alicia Hicks 2012 Indiana State University

Interactive Concept To Aid In Understanding Dimensional Analysis, Alicia Hicks

Symposium 2012

Many students struggle with learning how to utilize dimensional analysis. This confusion is due to not understanding the concept of dose per volume, leading to difficulty when starting the sequencing. This could be one of the contributing causes to medication errors in clinical practice. Does using models, such as Play-doh and pebbles, help students learn the concept of milligrams per milliliters when calculating dosages using dimensional analysis method? A series of pre- and post-tests are used to measure learning growth in each of the treatment groups. Three treatment groups were utilized: Control: one group had no intervention between the pre …


The Efficacy Of An Audio Program And Discussion Guide In Promoting Exclusive Breastfeeding In Cameroon, Africa, Kathryn R. Reinsma 2012 Loma Linda University

The Efficacy Of An Audio Program And Discussion Guide In Promoting Exclusive Breastfeeding In Cameroon, Africa, Kathryn R. Reinsma

Loma Linda University Electronic Theses, Dissertations & Projects

Background: In the Northwest Region of Cameroon, approximately 90% of women initiate breastfeeding; however, only 34% continue exclusive breastfeeding for the recommended six months (Kakute, et al., 2005; WHO, 2008). Entertainment-education is a mass-media communication strategy of placing educational information into media such as television programs, movies, and radio programs (Siegel & Lotenberg, 2007). This form of behavioral change communication has proven effective in addressing health-related issues in developing countries.

Purpose: The aim was to design an audio program and discussion guide to test the hypothesis that an audio program and discussion guide improves exclusive breastfeeding knowledge, beliefs, benefits, self-efficacy, …


Differential Patterns Of Interaction And Gaussian Graphical Models, Masanao Yajima, Donatello Telesca, Yuan Ji, Peter Muller 2012 UCLA, Statistics

Differential Patterns Of Interaction And Gaussian Graphical Models, Masanao Yajima, Donatello Telesca, Yuan Ji, Peter Muller

COBRA Preprint Series

We propose a methodological framework to assess heterogeneous patterns of association amongst components of a random vector expressed as a Gaussian directed acyclic graph. The proposed framework is likely to be useful when primary interest focuses on potential contrasts characterizing the association structure between known subgroups of a given sample. We provide inferential frameworks as well as an efficient computational algorithm to fit such a model and illustrate its validity through a simulation. We apply the model to Reverse Phase Protein Array data on Acute Myeloid Leukemia patients to show the contrast of association structure between refractory patients and relapsed …


Estimation Of Performance Indices For The Planning Of Sustainable Transportation Systems, Pankaj Maheshwari, Alexander Paz, Pushkin Kachroo 2012 University of Nevada, Las Vegas

Estimation Of Performance Indices For The Planning Of Sustainable Transportation Systems, Pankaj Maheshwari, Alexander Paz, Pushkin Kachroo

Graduate Publications & Presentations

What is sustainable transportation system?

Fulfill the needs of current generations without compromising the ability of future generations

Utilize resources without compromising their health and productivity Leads to development that improves quality of life

Assimilate economic, ecological, social, and bio-physical components of resource ecosystems

Minimize the use of renewable and non-renewable resources, provide affordability and equity between generations


Modeling Regional Radicarbon Trends: A Case Study From The East Texas Woodland Period, Robert Z. Selden Jr. 2012 Heritage Research Center, Stephen F. Austin State University

Modeling Regional Radicarbon Trends: A Case Study From The East Texas Woodland Period, Robert Z. Selden Jr.

CRHR: Archaeology

The East Texas Radiocarbon Database contributes to an analysis of tempo and place for Woodland era (~500 BC–AD 800) archaeological sites within the region. The temporal and spatial distributions of calibrated 14C ages (n = 127) with a standard deviation (ΔT) of 61 from archaeological sites with Woodland components (n = 51) are useful in exploring the development and geographical continuity of the peoples in east Texas, and lead to a refinement of our current chronological understanding of the period. While analysis of summed probability distributions (SPDs) produces less than significant findings due to sample size, they are used …


Poverty And Disability: A Vicious Circle? Evidence From Afghanistan And Zambia, Jean-Francois Trani, Mitchell M. Loeb 2012 Washington University in St. Louis, George Warren Brown School

Poverty And Disability: A Vicious Circle? Evidence From Afghanistan And Zambia, Jean-Francois Trani, Mitchell M. Loeb

Brown School Faculty Publications

Disability and poverty have a complex and interdependent relationship. It is commonly understood that persons with disabilities are more likely to be poor and that poverty may contribute to sustaining disability. This interdependency is revealed not only through an examination of poverty in terms of income but also on a broader scale through other poverty related dimensions. Just how robust is this link? This paper compares data collected from household surveys in Afghanistan and Zambia, and explores the potential link between multidimensional poverty and disability. We find evidence of lower access to health care, education and labour market for people …


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