Multivariate Analysis Commons^™

Models For Hsv Shedding Must Account For Two Levels Of Overdispersion, Amalia Magaret

UW Biostatistics Working Paper Series

We have frequently implemented crossover studies to evaluate new therapeutic interventions for genital herpes simplex virus infection. The outcome measured to assess the efficacy of interventions on herpes disease severity is the viral shedding rate, defined as the frequency of detection of HSV on the genital skin and mucosa. We performed a simulation study to ascertain whether our standard model, which we have used previously, was appropriately considering all the necessary features of the shedding data to provide correct inference. We simulated shedding data under our standard, validated assumptions and assessed the ability of 5 different models to reproduce the …

Spatiotemporal Meta-Analysis: Reviewing Health Psychology Phenomena Over Space And Time., Blair T. Johnson

CHIP Documents

This supplemental material is meant to support this article:

Johnson, B. T., Crowley, E., & Marrouch, N. Spatiotemporal meta-analysis: Reviewing health psychology phenomena over space and time. Health Psychology Review.

Specifically, it is a database of GDPs per capita for nations in the world between 1800 and 2015. It is archived here to support an online supplement to this article.

GDP per capita

A Comparison Of The Utility Of Craniometric And Dental Morphological Data For Assessing Biodistance And Sex-Differential Migration In The Pacific Islands, Brittney A. Eubank

Graduate Student Theses, Dissertations, & Professional Papers

Genetic analysis of maternally-inherited mitochondrial DNA and the paternally-inherited Y-chromosome yield contrasting pictures of movement of peoples into the Pacific Islands. A possible explanation for this discrepancy is a matrilocal residency pattern practiced by early Pacific settlers, in which Melanesian men were brought into settler communities to intermarry with local women, yielding a higher intrapopulation variance and lower interpopulation variance exhibited in males compared to females. This research investigates the possibility of sex-differential migration in the Oceanic populations of Easter Island, Fiji, Guam, Mokapu, and New Britain through analysis of biodistance based on dental morphological trait frequencies and craniometric measures …

Development In Normal Mixture And Mixture Of Experts Modeling, Meng Qi

Theses and Dissertations--Statistics

In this dissertation, first we consider the problem of testing homogeneity and order in a contaminated normal model, when the data is correlated under some known covariance structure. To address this problem, we developed a moment based homogeneity and order test, and design weights for test statistics to increase power for homogeneity test. We applied our test to microarray about Down’s syndrome. This dissertation also studies a singular Bayesian information criterion (sBIC) for a bivariate hierarchical mixture model with varying weights, and develops a new data dependent information criterion (sFLIC).We apply our model and criteria to birth- weight and gestational …

The Relationship Between Exercise And Depression And Anxiety In College Students, Joshua Frank, Dr. Amy Adkins, Nathan Thomas, Dr. Danielle Dick

UROP Posters

The literature shows an inverse association between exercise and mental disorders. The aim of this study is to further elaborate on this association with regards to exercise and its relationship with anxiety and depression in a college sample. The subject group focused on seniors in the Spit for Science data set which incorporated a total of 821 students. Physical activity was assessed using the International Physical Activity Questionnaire (IPAQ) to estimate the overall metabolic equivalents (MET’s) each student spent in walking, moderate, or vigorous activity levels in the previous week. Sum scores were used to measure depression and anxiety. Overall,the …

Provision Of Hospital-Based Palliative Care And The Impact On Organizational And Patient Outcomes, Marisa L. Roczen

Theses and Dissertations

Hospital-based palliative care services aim to streamline medical care for patients with chronic and potentially life-limiting illnesses by focusing on individual patient needs, efficient use of hospital resources, and providing guidance for patients, patients’ families and clinical providers toward making optimal decisions concerning a patient’s care. This study examined the nature of palliative care provision in U.S. hospitals and its impact on selected organizational and patient outcomes, including hospital costs, length of stay, in-hospital mortality, and transfer to hospice. Hospital costs and length of stay are viewed as important economic indicators. Specifically, lower hospital costs may increase a hospital’s profit …

Dimension Reduction And Variable Selection, Hossein Moradi Rekabdarkolaee

Theses and Dissertations

High-dimensional data are becoming increasingly available as data collection technology advances. Over the last decade, significant developments have been taking place in high-dimensional data analysis, driven primarily by a wide range of applications in many fields such as genomics, signal processing, and environmental studies. Statistical techniques such as dimension reduction and variable selection play important roles in high dimensional data analysis. Sufficient dimension reduction provides a way to find the reduced space of the original space without a parametric model. This method has been widely applied in many scientific fields such as genetics, brain imaging analysis, econometrics, environmental sciences, etc. …

Macrobenthic Communities In The Northern Gulf Of Mexico Hypoxic Zone: Testing The Pearson-Rosenberg Model, Shivakumar Shivarudrappa

Dissertations

The Pearson and Rosenberg (P-R) conceptual model of macrobenthic succession was used to assess the impact of hypoxia (dissolved oxygen [DO] ≤ 2 mg/L) on the macrobenthic community on the continental shelf of northern Gulf of Mexico for the first time. The model uses a stress-response relationship between environmental parameters and the macrobenthic community to determine the ecological condition of the benthic habitat. The ecological significance of dissolved oxygen in a benthic habitat is well understood. In addition, the annual recurrence of bottom-water hypoxia on the Louisiana/Texas shelf during summer months is well documented.

The P-R model illustrates the decreasing …

Dynapenic Obesity And The Effect On Long-Term Physical Function And Quality Of Life: Data From The Osteoarthritis Initiative, John A. Batsis, Alicia J. Zbehlik, Dawna Pidgeon, Stephen J. Bartels

Dartmouth Scholarship

Obesity is associated with functional impairment, institutionalization, and increased mortality risk in elders. Dynapenia is defined as reduced muscle strength and is a known independent predictor of adverse events and disability. The synergy between dynapenia and obesity leads to worse outcomes than either independently. We identified the impact of dynapenic obesity in a cohort at risk for and with knee osteoarthritis on function.

Model Selection For Gaussian Mixture Models For Uncertainty Qualification, Yiyi Chen, Guang Lin, Xuan Liu

The Summer Undergraduate Research Fellowship (SURF) Symposium

Clustering is task of assigning the objects into different groups so that the objects are more similar to each other than in other groups. Gaussian Mixture model with Expectation Maximization method is the one of the most general ways to do clustering on large data set. However, this method needs the number of Gaussian mode as input(a cluster) so it could approximate the original data set. Developing a method to automatically determine the number of single distribution model will help to apply this method to more larger context. In the original algorithm, there is a variable represent the weight of …

Using Spatiotemporal Methods To Fill Gaps In Energy Usage Interval Data, Kristin K. Graves

Theses and Dissertations

Researchers analyzing spatiotemporal or panel data, which varies both in location and over time, often find that their data has holes or gaps. This thesis explores alternative methods for filling those gaps and also suggests a set of techniques for evaluating those gap-filling methods to determine which works best.

The Effects Of Quantitative Easing In The United States: Implications For Future Central Bank Policy Makers, Matthew Q. Rubino

Senior Honors Projects, 2010-2019

The purpose of this thesis is to examine the effects of the Federal Reserve’s recent bond buying programs, specifically Quantitative Easing 1, Quantitative Easing 2, Operation Twist (or the Fed’s Maturity Extension Program), and Quantitative Easing 3. In this study, I provide a picture of the economic landscape leading up to the deployment of the programs, an overview of quantitative easing including each program’s respective objectives, and how and why the Fed decided to implement the programs. Using empirical analysis, I measure each program’s effectiveness by applying four models including a yield curve model, an inflation model, a money supply …

Examining The Performance Of The Metropolis-Hastings Robbins-Monro Algorithm In The Estimation Of Multilevel Multidimensional Irt Models, Bozhidar M. Bashkov

Dissertations, 2014-2019

The purpose of this study was to review the challenges that exist in the estimation of complex (multidimensional) models applied to complex (multilevel) data and to examine the performance of the recently developed Metropolis-Hastings Robbins-Monro (MH-RM) algorithm (Cai, 2010a, 2010b), designed to overcome these challenges and implemented in both commercial and open-source software programs. Unlike other methods, which either rely on high-dimensional numerical integration or approximation of the entire multidimensional response surface, MH-RM makes use of Fisher’s Identity to employ stochastic imputation (i.e., data augmentation) via the Metropolis-Hastings sampler and then apply the stochastic approximation method of Robbins and Monro …

Exact Statistical Inferences For Functions Of Parameters Of The Log-Gamma Distribution, Joseph F. Mcdonald

UNLV Theses, Dissertations, Professional Papers, and Capstones

The log-gamma model has been used extensively for flood frequency analysis and is an important distribution in reliability, medical and other areas of lifetime testing. Conventional methods fails to provide exact solutions for the log-gamma model while asymptotic methods provide approximate solutions that often have poor performance for typical sample sizes. The two parameter log-gamma distribution is examined using the generalized p-value approach. The methods are exact in the sense that the tests and the confidence intervals are based on exact probability statements rather than on asymptotic approximations. Exact tests and exact confidence intervals for the parameter of interest based …

Bootstrapping Vs. Asymptotic Theory In Property And Casualty Loss Reserving, Andrew J. Difronzo Jr.

Honors Projects in Mathematics

One of the key functions of a property and casualty (P&C) insurance company is loss reserving, which calculates how much money the company should retain in order to pay out future claims. Most P&C insurance companies use non-stochastic (non-random) methods to estimate these future liabilities. However, future loss data can also be projected using generalized linear models (GLMs) and stochastic simulation. Two simulation methods that will be the focus of this project are: bootstrapping methodology, which resamples the original loss data (creating pseudo-data in the process) and fits the GLM parameters based on the new data to estimate the sampling …

Relationship Between High School Math Course Selection And Retention Rates At Otterbein University, Lauren A. Fisher

Undergraduate Honors Thesis Projects

Binary logistic regression was used to study the relationship between high school math course selection and retention rates at Otterbein University. Graduation rates from postsecondary institutions are low in the United States and, more specifically, at Otterbein. This study is important in helping to determine what can raise retention rates, and ultimately, graduation rates. It directs focus toward high school math course selection and what should be changed before entering a post-secondary institution. Otterbein will have a better idea of what type of students to recruit and which students may be good candidates with some extra help. Recruiting is expensive, …

Assessing The Social And Ecological Factors That Influence Childhood Overweight And Obesity, Katie Callahan

Electronic Theses and Dissertations

The prevalence of childhood overweight and obesity is increasing at an alarming rate in the United States. Currently more than 1 in 3 children aged 2-19 are overweight or obese. This is of major concern because childhood overweight and obesity leads to chronic conditions such as type II diabetes and tracks into adulthood, where more severe adverse health outcomes arise. In this study I used the premise of the social ecological model (SEM) to analyze the common levels that a child is exposed to daily; the intrapersonal level, the interpersonal level, the school level, and the community level to better …

Successful Mdr-Tb Treatment Regimens Including Amikacin Are Associated With High Rates Of Hearing Loss, Chawangwa Modongo, Rafal S. Sobota, Boikobo Kesenogile, Ronald Ncube

Dartmouth Scholarship

Aminoglycosides are a critical component of multidrug-resistant tuberculosis (MDR-TB) treatment but data on their efficacy and adverse effects in Botswana is scarce. We determined the effect of amikacin on treatment outcomes and development of hearing loss in MDR-TB patients. Patients started on MDR-TB treatment between 2006 and 2012 were included. Multivariate analysis was used to determine the effect of amikacin on treatment outcomes and development of hearing loss.

The Structure Of Child And Adolescent Aggression: Confirmatory Factor Analysis Of A Brief Peer Conflict Scale, Justin Russell

LSU New Orleans Theses and Dissertations

The importance of simultaneous consideration of forms and functions in youth measures of aggressive behavior is well established. Competing models have presented these highly interrelated constructs as either independent (e.g., reactive or overt) or paired factors (e.g., reactive and overt). The current study examines these models in the context of assessing the viability of a new self-report measure, the Peer Conflict Scale – 20 Item Version. Confirmatory factor analyses were conducted on PCS 20 responses from 1,048 school-age youth living in the Gulf Coast region. Both models significantly improved upon one or two-factor alternatives, and demonstrated partial invariance across gender …

Linking Instrumental Neutron Activation Analysis (Inaa) With Geology In The Ancestral Caddo Region, Robert Z. Selden Jr.

CRHR: Archaeology

This poster illustrates the success of a novel method of INAA that was employed to reveal geochemical signatures in Caddo ceramic vessel sherds that correlate with local surficial geology. The geochemical data from the sherd assemblage were used within an exploration of potential ceramic provenance, which was successful at demarcating sherds from ceramic vessels made from clays in either the Claiborne or Wilcox Groups. Further geochemical segregation was also apparent between the Recklaw Formation in the Claiborne Group, and the Weches Formation in the Wilcox Group. These results point to a high degree of geochemical variability within the East Texas …