Analytical Chemistry Commons^™

The Effects Of Cold Plasma Treatment On Sweet Basil (Ocimum Basilicum), Sauvelson Auguste

Seton Hall University Dissertations and Theses (ETDs)

The study discussed herein looks both to continue and to expand upon previous work conducted here at Seton Hall University, which investigated the effect of cold plasma processing on sweet basil and their essential oils. It was found that the application of cold plasma treatment increases plant growth and eugenol concentration, which is an essential oil component and one of the potential natural antioxidants used in food preservation. In this study, we considered methods for increasing the production and harvesting of plants that produce essential oils such as sweet basil (Ocimum basilicum). The study also incorporated more controls …

Investigation Of Vaporization Enthalpies And Vapor Pressures Of Organic Compounds By Correlation Gas Chromatography, Carissa Nelson

Dissertations

Thermodynamic properties of organic compounds are useful to scientists and manufacturers in many areas of research and technology. This work focuses on measuring and reporting these properties on materials of commercial, environmental and scientific interest. Vaporization enthalpies and vapor pressures of several organic compounds have been studied using correlation gas chromatography (CGC) and are reported here as well as in recent publications. The CGC method allows for the indirect measurement of these properties in instances where these materials are available only in mixtures or in very small amounts.

The qualities of these measurements for any chosen target are directly related …

Cross Photoreaction Of Glyoxylic And Pyruvic Acids In Model Aqueous Aerosol, Sha-Sha Xia, Alexis J. Eugene, Marcelo I. Guzman

Chemistry Faculty Publications

Aerosols of variable composition, size, and shape are associated with public health concerns as well as with light-particle interactions that play a role in the energy balance of the atmosphere. Photochemical reactions of 2-oxocarboxylic acids in the aqueous phase are now known to contribute to the total secondary organic aerosol (SOA) budget. This work explores the cross reaction of glyoxylic acid (GA) and pyruvic acid (PA) in water, the two most abundant 2-oxocarboxylic acids in the atmosphere, under solar irradiation and dark thermal aging steps. During irradiation, PA and GA are excited and initiate proton-coupled electron transfer or hydrogen abstraction …

Nmr Structural Investigation Of Chlamydial Protein Complex And Lysine Glycomimetic For Drug Design, Abigael Chebichiy Songok

LSU Doctoral Dissertations

Research and design of drugs for treatment against microbial infections require the study of pathogenic proteins involved during infection and replication. Drugs can be designed to interfere with the interaction network of these pathogenic proteins and inhibit the infection process. Determination of the structure and ligands of the target proteins in microbes is essential for designing mechanistic-based drugs. Two Chlamydia proteins involved in host cell invasion were investigated in this study. The goal is to identify amino acids involved at the binding interface of Chlamydia chaperon proteins Scc1 and Scc4 by solution NMR spectroscopy. This information will give a lead …

Development Of Chemistry Activities For Local Outreach In Stem, Emily Knight

Chemistry & Biochemistry Student Projects

Introduction: This research project was started because of an increase in outreach opportunities for the Department of Chemistry and Biochemistry. For similar opportunities, we now have bins of content that are simple to use, encouraging more students to participate in volunteer research.

Purpose: to find, modify, and/or create grade-level appropriate labs and demonstration activities for 5th-8th graders, with a specific focus on activities hat involve easily available components. These activities are intended to be used for outreach to local schools by chemistry student volunteers and released online to act as a resource for teachers.

Educational Resources: Polymers, Emily Knight

Chemistry & Biochemistry Student Projects

The document is meant to act as a resource for elementary through middle school teachers, featuring a science activity connected to Indiana state standards with grade-appropriate science connections aimed toward 5th, 6th, 7th, and 8th grade.

This document contains 3 polymer-based activities demonstrating different properties of polymers - the physical characteristics, possible absorbency, and elasticity. These activities can be abbreviated and used in rotating stations, planned over multiple days, or you can pick on that fits best with the classroom environment.

Educational Resources: Ionic Matching, Emily Knight

Chemistry & Biochemistry Student Projects

The document is meant to act as a resource for elementary through middle school teachers, featuring a science activity connected to Indiana state standards with grade-appropriate science connections aimed toward 5th, 6th, 7th, and 8th grade.

The entire point of this piece is simply to introduce balancing charges in ionic compounds. This is a simpler method to get students thinking about the idea, which also makes it suitable for pre-high school students. It gives a visual representation of how charges balance and cow cations pair with anions. At this level, it is very similar to least common denominator calculations.

Educational Resources: Homemade Fluorometer, Emily Knight

Chemistry & Biochemistry Student Projects

The document is meant to act as a resource for elementary through middle school teachers, featuring a science activity connected to Indiana state standards with grade-appropriate science connections aimed toward 5th, 6th, 7th, and 8th grade.

Educational Resources: Exchange Rates And Unit Conversion, Emily Knight

Chemistry & Biochemistry Student Projects

The document is meant to act as a resource for elementary through middle school teachers, featuring a science activity connected to Indiana state standards with grade-appropriate science connections aimed toward 5th, 6th, 7th, and 8th grade.

Students might have experience in 3rd-6th grade with converting basic ideas such as volume and measurements. This is intended to expand that idea and introduce the mole. It's also a general interactive conversion/exchange activity. All items in here are just based on what we had available and convenient, so feel free to swap out items such as rubber stoppers with something more easily available …

Educational Resources: Curie Point Engine, Emily Knight

Chemistry & Biochemistry Student Projects

The document is meant to act as a resource for elementary through middle school teachers, featuring a science activity connected to Indiana state standards with grade-appropriate science connections aimed toward 5th, 6th, 7th, and 8th grade.

The Curie point of a metal is the temperature at which it loses its magnetic characteristics. Heat can cause magnets to stop being magnetic, which is why heating up magnets is not advised. The engine works because the Curie point of nickel is 354 degrees Celsius, a temperature that can be reached with a simple candle flame. Included are instructions about how to build …

Educational Resources: Magnets, Emily Knight

Chemistry & Biochemistry Student Projects

No abstract provided.

Advances In Amino Acid Analysis For Marine Related Matrices And Its Application To Coastal Shelf Settings In The Canadian Arctic, Rachel M. Mcmahon

OES Theses and Dissertations

Amino acids comprise up to 50% of organic matter in cellular material and are a major fraction of oceanic organic carbon. Amino acids are also considered highly labile during organic matter recycling, making them useful proxies for organic carbon cycling. Nevertheless, analysis of individual amino acids has been burdened by lengthy derivatization and complex analysis since the 1950s. In this thesis, I describe the modification of advanced analytical techniques, developed in the biomedical field, for analysis of marine matrices which allow the determination of at least 40 amino acids without the need for lengthy sample preparation and derivatization, twice the …

Carbon Composite Fe3O4 Nanoparticles Based Electrochemical Sensor For Hydrogen Peroxide Detection, Si-Yu Zhang, Hui-Juan Wang, Shu-Fang Li, Jian-Ying Qu

Journal of Electrochemistry

In this work, a novel hydrogen peroxide electrochemical sensor was constructed with ferroferric oxide (Fe₃O₄) magnetic nanoparticles, which demonstrated good electrocatalytic activity for hydrogen peroxide. There existed a good linear relationship between the concentration of hydrogen peroxide and the oxidation peak current in the range of 1.00 × 10^-6 ~ 1.00 × 10^-3 mol·L^-1 (R = 0.9980) with the detection limit of 6.60 × 10-7 mol·L^-1. The sensor exhibited good anti-interference ability, high reproducibility and stability.

Hydrophilic Interaction Liquid Chromatography-Electrospray Ionization Mass Spectrometry For Therapeutic Drug Monitoring Of Metformin And Rosuvastatin In Human Plasma, Nikolaos Antonopoulos, Giorgos Machairas, George Migias, Ariadni Vonaparti, Vasiliki Brakoulia, Constantinos Pistos, Dimitra Gennimata, Irene Panderi

Chemistry Faculty Publications

In this work a hydrophilic interaction liquid chromatography/positive ion electrospray mass spectrometric assay (HILIC/ESI-MS) has been developed and fully validated for the quantitation of metformin and rosuvastatin in human plasma. Sample preparation involved the use of 100 µL of human plasma, following protein precipitation and filtration. Metformin, rosuvastatin and 4-[2-(propylamino) ethyl] indoline 2 one hydrochloride (internal standard) were separated by using an X-Bridge-HILIC BEH analytical column (150.0 × 2.1 mm i.d., particle size 3.5 µm) with isocratic elution. A mobile phase consisting of 12% (v/v) 15 mM ammonium formate water solution in acetonitrile was used for the separation and pumped …

Steric Effects Of Alkyl Ammonium Salts On The Combustion Of Exchanged Smectite Clays, Celeste A. Keith

Electronic Theses and Dissertations

Bomb calorimetry was explored as a new method for determining the cation exchange capacity (CEC) of clays. Smectite clays were modified with several alkyl ammonium salts varying in number of carbons and the spatial orientation of the carbons about the central nitrogen atom. The clays used, standards purchased from the Source Clay Repository, have CECs of 44, 80, 88, and 120 meq/100 g. Theoretically, the combustion energy of the organo-clays should be approximately the same for each salt. Any differences in energy would be due to the different structures of the salts and how they are oriented in the interlamellar …

Removal Of Pb2+ Ions From Consuming Water Using A Fabricated Water Filter For Home Use, Pantaree Sodkhoksoong, Papidchaya Chanpong, Thunyarus Rodsawatchuchoke

The International Student Science Fair 2018

Lead contamination in water is one of the worldwide concerned environmental problems. For example, lead leaking from pipe corrosion and solder has been found contaminated in consuming water in many U.S. areas. The uncontrolled release of effluents containing lead from various industries has also caused lead-contaminated water in Thailand. Exposing to lead-contaminated water can lead to serious symptoms (e.g. fatigue, headaches, abdominal pain, irritability, depression, and seizures) or even death. Therefore, the elimination of lead ions (Pb²⁺) from consuming water or from effluents before releasing into the environment is necessary. The selection of adsorbents and the fabrication of …

Quantitative Proteomics To Support Translational Cancer Research, Melissa Hoffman

USF Tampa Graduate Theses and Dissertations

Altered signaling pathways, which are mediated by post-translational modifications and changes in protein expression levels, are key regulators of cancer initiation, progression, and therapeutic escape. Many aspects of cancer progression, including early carcinogenesis and immediate response to drug treatment, are beyond the scope of genetic profiling and non-invasive monitoring techniques. Global protein profiling of cancer cell line models, tumor tissues, and biofluids (e.g. serum or urine) using mass spectrometry-based proteomics produces novel biological insights, which support improved patient outcomes. Recent technological advances resulting in next-generation mass spectrometry instrumentation and improved bioinformatics workflows have led to unprecedented measurement reproducibility as well …

Visualization And Quantification Of Cancer-Associated Enzymes With Fluorescent Small-Molecule Substrate Probes, Zhenhua Shen

LSU Doctoral Dissertations

Fluorescence imaging can be used both as a tool to diagnose diseases and guide treatment in clinical settings, and as a technique to monitor dynamic events or biological species in basic research. Therefore, there is a great need for the development of a multitude of fluorescent probes that can be incorporated with fluorescence imaging techniques to track and report endogenous enzymes with high specificity and selectivity. In contrast to always-on and targeted always-on fluorescent probes that continually emit light, activity-based substrate probes either emit low numbers of photons or are completely quenched. They can be converted to highly fluorescent reporters …

An Improved Method For The Analysis Of Fiber Evidence Using Polarized Light Microscopy, Samuel F. Kaplan

Student Theses

Using the basic fundamentals of polarized light microscopy, a new and improved method for identifying synthetic fibers is presented in this thesis. Using the equation of an ellipse in spherical coordinates, an EXCEL™ (Microsoft Inc., Seattle, WA) spreadsheet was developed that generated tables of data that provide a foundation for a new and more efficient method in fiber analysis. Intermediate refractive index values for each subclass of textile fibers were calculated based on the fiber's principal refractive index values. The angles of refractive index matching to known refractive index fluids vary from 0 to 90 degrees upon rotation of the …

Assessment Of The Viability Of Microwell Plates As Sample Holders For Analytical Excitation-Emission Spectroscopy Of Polyaromatic Hydrocarbons In 75% Ethanol, Lauren M. Ridley-Hoffman

Seton Hall University Dissertations and Theses (ETDs)

Polyaromatic hydrocarbons (PAHs) in the environment are a significant concern as many compounds in this class are potential carcinogens. PAHs resulting from petroleum spills can contaminate natural waters and the products obtain from them (fish and fish products in particular). Previous studies by Pena, et. al. on ethanolic extracts of organs from menhaden captured in the vicinity of the Deepwater Horizon (Macondo oil well) spill have shown that fluorescence excitation spectroscopy is a useful technique for detecting the presence of PAH metabolites and fluorescent vitamins. The study has also concluded that previous methods for analyzing PAHs using fluorescence spectroscopy used …