Open Access. Powered by Scholars. Published by Universities.®

Clinical Epidemiology Commons

Open Access. Powered by Scholars. Published by Universities.®

992 Full-Text Articles 2,449 Authors 497,031 Downloads 94 Institutions

All Articles in Clinical Epidemiology

Faceted Search

992 full-text articles. Page 4 of 37.

Covid-19 And Severe Acute Respiratory Infection, Steven C. Hatch 2020 University of Massachusetts Medical School

Covid-19 And Severe Acute Respiratory Infection, Steven C. Hatch

PEER Liberia Project

This presentation provides an overview of Severe Acute Respiratory Infection (SARI) and COVID-19, with following objectives: characterize current & near-future epidemiology of COVID-19 outbreak; provide general clinical features of SARI due to COVID; outline clinical management of COVID.


Covid-19 In The Pediatric Population, Patricia A. McQuilkin 2020 University of Massachusetts Medical School

Covid-19 In The Pediatric Population, Patricia A. Mcquilkin

PEER Liberia Project

This presentation provides an overview of a recent study and its implications pertaining to COVID-19 for pediatric patients.


Circulating Calcium, Phosphorus, And Parathyroid Hormone And Aggressive Prostate Cancer In The North Carolina-Louisiana Prostate Cancer Project, Brittany Crawford 2020 University of South Carolina

Circulating Calcium, Phosphorus, And Parathyroid Hormone And Aggressive Prostate Cancer In The North Carolina-Louisiana Prostate Cancer Project, Brittany Crawford

Theses and Dissertations

Prostate cancer is the most commonly diagnosed cancer among men in the United States. Despite improvements in screening, diagnostic methods, and treatment, African-American men have an increased risk of total and aggressive prostate cancer. In recent years, a growing body of evidence linking biomarkers of calcium and parathyroid hormone (PTH) to prostate cancer development has emerged. Circulating calcium, phosphorus, and PTH are homeostatically related. Prior studies linking prostate cancer and circulating calcium and PTH have produced inconclusive results, and no studies have examined the association between serum phosphorus and prostate cancer. The present study examined the relationship between circulating calcium ...


Prevalence And Trends Of Asthma In United States (Us) Adults, 2005-2016: A National Health And Nutrition Examination Survey (Nhanes) Study, Oluwakemi A. Akinniyi MPH, Sedoafia Amelor MPH, Keya Dushyant Desai MPH, Jocelyn K. Elias MPH, Ankita Patel MPH, Sandeep Krishna Reddy MPH, Maureen Kennedy DrPH 2020 New York Medical College School of Health Sciences and Practice

Prevalence And Trends Of Asthma In United States (Us) Adults, 2005-2016: A National Health And Nutrition Examination Survey (Nhanes) Study, Oluwakemi A. Akinniyi Mph, Sedoafia Amelor Mph, Keya Dushyant Desai Mph, Jocelyn K. Elias Mph, Ankita Patel Mph, Sandeep Krishna Reddy Mph, Maureen Kennedy Drph

Annual SHSP Student Research and Scholarship Day

No abstract provided.


An Examination Between Neighborhood Characteristics And Alzheimer’S Disease And Related Dementias And Caregiver Mental Health In South Carolina, Dana Mahmoud AlHasan 2020 University of South Carolina

An Examination Between Neighborhood Characteristics And Alzheimer’S Disease And Related Dementias And Caregiver Mental Health In South Carolina, Dana Mahmoud Alhasan

Theses and Dissertations

Research has examined the relationship between neighborhood environments and cognitive decline, yet few have investigated the role of neighborhood characteristics specifically on incident Alzheimer’s disease and related dementias (ADRD), on severity of Alzheimer’s disease (AD) including neuropsychiatric symptoms (NPS), and on caregiver mental health including depressive symptoms. This dissertation aimed to 1) ecologically examine the geographic distribution of ADRD and investigate ecologic associations between census-tract neighborhood characteristics and diagnosed ADRD case incidence from 2010-2014 in the South Carolina (SC) Alzheimer’s Disease Registry; 2) estimate the cross-sectional association between neighborhood characteristics and NPS among those with AD in ...


Crisaborole And Quality Of Life In Patients With Mild To Moderate Atopic Dermatitis: A Public Health Approach, Alejandra Puerta, Elizabeth Drugge PhD, MPH, Ellen Loh BSPharm, MBA, PhD 2020 Dept. of Public Health, Epidemiology Division, New York Medical College

Crisaborole And Quality Of Life In Patients With Mild To Moderate Atopic Dermatitis: A Public Health Approach, Alejandra Puerta, Elizabeth Drugge Phd, Mph, Ellen Loh Bspharm, Mba, Phd

Annual SHSP Student Research and Scholarship Day

We conducted a literature review to explore the effect of Crisaborole on patient QoL associated with mild to moderate atopic dermatitis.


Liposomal Bupivacaine Results In Cost Savings While Managing Post-Operative Pain In Fragility Intertrochanteric Hip Fractures, Nainisha Chintalapudi, Avinesh Agarwalla MD, Joana Lu PA, Hrayr G. Basmajian MD, Joseph N. Liu MD, Nirav H. Amin MD 2020 Westchester Medical Center

Liposomal Bupivacaine Results In Cost Savings While Managing Post-Operative Pain In Fragility Intertrochanteric Hip Fractures, Nainisha Chintalapudi, Avinesh Agarwalla Md, Joana Lu Pa, Hrayr G. Basmajian Md, Joseph N. Liu Md, Nirav H. Amin Md

Annual SHSP Student Research and Scholarship Day

No abstract provided.


The Impact Of Psychosocial, Clinical, And Neighborhood Factors On Inflammatory Outcomes Among African American Women, Malcolm Seth Bevel 2020 University of South Carolina

The Impact Of Psychosocial, Clinical, And Neighborhood Factors On Inflammatory Outcomes Among African American Women, Malcolm Seth Bevel

Theses and Dissertations

Inflammatory-related chronic diseases are disparagingly prevalent among African Americans in the United States, particularly in the Southeastern region. Access to community gardens shows promise in mitigating chronic disease outcomes, despite multiple barriers to physical activity and diet among underserved populations. We seek to determine if psychosocial or clinical factors mediate the association between the treatment effect of a healthy lifestyle intervention and inflammatory biomarker levels among African American women, respectively. We also seek to analyze the relationship between residing in a food desert/swamp and inflammatory biomarker levels, while gaining a qualitative perspective about community garden access among African American ...


Coronavirus Disease 2019 (Covid-19), Matthew Dunbar 2020 Ohio Northern University

Coronavirus Disease 2019 (Covid-19), Matthew Dunbar

Pharmacy Student Scholarship

No abstract provided.


Vaccine Confidence, Coverage, And Hesitancy Worldwide: A Literature Analysis Of Vaccine Hesitancy And Potential Causes Worldwide, Jordan Hammond 2020 University of South Carolina - Columbia

Vaccine Confidence, Coverage, And Hesitancy Worldwide: A Literature Analysis Of Vaccine Hesitancy And Potential Causes Worldwide, Jordan Hammond

Senior Theses

Vaccines are one of the world’s most impactful medical therapies. They are cost-effective, successfully proven, and one of the quickest treatment options available today (Clark et al., 2016). They save millions of lives every year and have eliminated certain diseases on a national and international level. However, millions of people worldwide still remain unvaccinated. In developed nations, mainly The United States (U.S.) and the European countries, many of the unvaccinated are a result of rising vaccine hesitancy of parents in conjunction with the anti-vaccination movement. Vaccine hesitancy is defined as “a delay in acceptance or refusal of vaccines ...


The Interaction Between Caffeine Consumption, Alcohol Use, And Amount Of Sleep On Bone Health, Haley Davis-Martin 2020 University of South Carolina

The Interaction Between Caffeine Consumption, Alcohol Use, And Amount Of Sleep On Bone Health, Haley Davis-Martin

Theses and Dissertations

Using cross-sectional data from the 2009-2010 and 2013-2014 NHANES surveys we examined potential interaction between caffeine consumption, alcohol use, and sleep and its relation to bone health, measured using bone mineral density (BMD). The study population consisted of 2,405 individuals at least 40 years old who were not taking any medications or hormones that would affect bone mineral density. Several factors such as smoking status, exercise, dietary intake of calcium, dietary intake of vitamin D, dietary intake of phosphorus, presence of arthritis, age, gender and race were considered in this project. We found a statistically significant negative linear relationships ...


Surveying Tuberculosis Screening Practices Of South Carolina Hospital Employees, Tamara T. Carree 2020 University of South Carolina

Surveying Tuberculosis Screening Practices Of South Carolina Hospital Employees, Tamara T. Carree

Theses and Dissertations

BACKGROUND: Every year tuberculosis (TB) causes over 10 millions of people globally and in recent years has caused over 9,000 cases annually in the United States. TB can be transmitted in hospital settings, and South Carolina hospitals, like hospitals elsewhere in the country maintain a responsibility to test their employees for this disease. Nosocomial infections of active TB among patients and healthcare workers can be burdensome on hospital resources. Testing healthcare workers and implementing prevention strategies are examples of administrative controls provided in the 2005 guidelines by the Centers for Disease Control and Prevention (CDC). Implementation of administrative controls ...


The Association Between Patient-Reported Clinical Factors And 30-Day Acute Care Utilization In Chronic Heart Failure, Jinying Chen, Rajani S. Sadasivam, Amanda C. Blok, Christine S. Ritchie, Catherine S. Nagawa, Elizabeth Aaker Orvek, Kanan Patel, Thomas K. Houston 2020 University of Massachusetts Medical School

The Association Between Patient-Reported Clinical Factors And 30-Day Acute Care Utilization In Chronic Heart Failure, Jinying Chen, Rajani S. Sadasivam, Amanda C. Blok, Christine S. Ritchie, Catherine S. Nagawa, Elizabeth Aaker Orvek, Kanan Patel, Thomas K. Houston

Population and Quantitative Health Sciences Publications

BACKGROUND: Heart failure patients have high rates of repeat acute care use. Current efforts for risk prediction often ignore postdischarge data.

OBJECTIVE: To identify postdischarge patient-reported clinical factors associated with repeat acute care use.

RESEARCH DESIGN: In a prospective cohort study that followed patients with chronic heart failure for 30 days postdischarge, for 7 days after discharge (or fewer days if patients used acute care within 7 days postdischarge), patients reported health status, heart failure symptoms, medication management, knowledge of follow-up plans, and other issues using a daily interactive automatic phone call.

SUBJECTS: A total of 156 patients who had ...


Investigating The Impact Of Asymptomatic Carriers On Covid-19 Transmission [Preprint], Jacob B. Aguilar, Jeremy Samuel Faust, Lauren M. Westafer, Juan B. Gutierrez 2020 Saint Leo University

Investigating The Impact Of Asymptomatic Carriers On Covid-19 Transmission [Preprint], Jacob B. Aguilar, Jeremy Samuel Faust, Lauren M. Westafer, Juan B. Gutierrez

COVID-19 Publications by UMMS Authors

Coronavirus disease 2019 (COVID-19) is a novel human respiratory disease caused by the SARS-CoV-2 virus. Asymptomatic carriers of the virus display no clinical symptoms but are known to be contagious. Recent evidence reveals that this sub-population, as well as persons with mild, represent a major contributor in the propagation of COVID-19. The asymptomatic sub-population frequently escapes detection by public health surveillance systems. Because of this, the currently accepted estimates of the basic reproduction number (Ro) of the virus are inaccurate. It is unlikely that a pathogen can blanket the planet in three months with an Ro in the vicinity of ...


First Aid First: Implementation And Evaluation Of A Community-Based First Aid Training Course, Luke Wesemann 2020 Wayne State University

First Aid First: Implementation And Evaluation Of A Community-Based First Aid Training Course, Luke Wesemann

Medical Student Research Symposium

In 2018, medical students at Wayne State University School of Medicine (WSUSOM) created a first aid training initiative called First Aid First (FAF). FAF is a comprehensive community-based training program that teaches lifesaving skills tailored for Detroit. The objective of this initiative was to improve the confidence and basic first aid skills of those who attend trainings.

Pre- and post-test surveys were used to measure knowledge, confidence and skill level. The survey data gathered from March 2018-October 2019 consisted of 5 Likert scale questions for self-evaluation component and 23-25 multiple choice questions, number depending on time of administration due to ...


Changing Trends In The Landscape Of Patients Hospitalized With Acute Myocardial Infarction (2001 To 2011) (From The Worcester Heart Attack Study), Regino Mercado-Lubo, Jorge Yarzebski, Darleen M. Lessard, Joel M. Gore, Robert J. Goldberg 2020 University of Massachusetts Medical School

Changing Trends In The Landscape Of Patients Hospitalized With Acute Myocardial Infarction (2001 To 2011) (From The Worcester Heart Attack Study), Regino Mercado-Lubo, Jorge Yarzebski, Darleen M. Lessard, Joel M. Gore, Robert J. Goldberg

Population and Quantitative Health Sciences Publications

During the past several decades, new diagnostic tools, interventional approaches, and population-wide changes in the major coronary risk factors have taken place. However, few studies have examined relatively recent trends in the demographic characteristics, clinical profile, and the short-term outcomes of patients hospitalized for acute myocardial infarction (AMI) from the more generalizable perspective of a population-based investigation. We examined decade long trends (2001 to 2011) in patient's demographic and clinical characteristics, treatment practices, and hospital outcomes among residents of the Worcester metropolitan area hospitalized with an initial AMI (n=3,730) at all 11 greater Worcester medical centers during ...


Simulation-Based Power And Sample Size Calculation For Designing Interrupted Time Series Analyses Of Count Outcomes In Evaluation Of Health Policy Interventions, Wei Liu, Shangyuan Ye, Bruce A. Barton, Melissa A. Fischer, Colleen Lawrence, Elizabeth J. Rahn, Maria I. Danila, Kenneth G. Saag, Paul A. Harris, Stephenie C. Lemon, Jeroan J. Allison, Bo Zhang 2020 Harbin Institute of Technology

Simulation-Based Power And Sample Size Calculation For Designing Interrupted Time Series Analyses Of Count Outcomes In Evaluation Of Health Policy Interventions, Wei Liu, Shangyuan Ye, Bruce A. Barton, Melissa A. Fischer, Colleen Lawrence, Elizabeth J. Rahn, Maria I. Danila, Kenneth G. Saag, Paul A. Harris, Stephenie C. Lemon, Jeroan J. Allison, Bo Zhang

Population and Quantitative Health Sciences Publications

Objective: The purpose of this study was to present the design, model, and data analysis of an interrupted time series (ITS) model applied to evaluate the impact of health policy, systems, or environmental interventions using count outcomes. Simulation methods were used to conduct power and sample size calculations for these studies.

Methods: We proposed the models and analyses of ITS designs for count outcomes using the Strengthening Translational Research in Diverse Enrollment (STRIDE) study as an example. The models we used were observation-driven models, which bundle a lagged term on the conditional mean of the outcome for a time series ...


Combining Genomics And Epidemiology To Track Mumps Virus Transmission In The United States, Shirlee Wohl, Lawrence C. Madoff, Bronwyn L. MacInnis 2020 Harvard University

Combining Genomics And Epidemiology To Track Mumps Virus Transmission In The United States, Shirlee Wohl, Lawrence C. Madoff, Bronwyn L. Macinnis

Open Access Publications by UMMS Authors

Unusually large outbreaks of mumps across the United States in 2016 and 2017 raised questions about the extent of mumps circulation and the relationship between these and prior outbreaks. We paired epidemiological data from public health investigations with analysis of mumps virus whole genome sequences from 201 infected individuals, focusing on Massachusetts university communities. Our analysis suggests continuous, undetected circulation of mumps locally and nationally, including multiple independent introductions into Massachusetts and into individual communities. Despite the presence of these multiple mumps virus lineages, the genomic data show that one lineage has dominated in the US since at least 2006 ...


Seek And You Shall Find: Is Routine Duplex Ultrasound Screening For Deep Vein Thrombosis In Trauma Warranted?, Ashley Thompson MD, Krista Miller MD, Tatiana R. Eversley-Kelso MPH, Eric Shaw PhD, James Dunne MD, Heather MacNew MD, FACS 2020 HCA Healthcare

Seek And You Shall Find: Is Routine Duplex Ultrasound Screening For Deep Vein Thrombosis In Trauma Warranted?, Ashley Thompson Md, Krista Miller Md, Tatiana R. Eversley-Kelso Mph, Eric Shaw Phd, James Dunne Md, Heather Macnew Md, Facs

General Surgery

See additional files


Identifying Unreliable Predictions In Clinical Risk Models, Paul D. Myers, Kenney Ng, Kristen Severson, Uri Kartoun, Wangzhi Dai, Wei Huang, Frederick A. Anderson Jr., Collin M. Stultz 2020 Massachusetts Institute of Technology

Identifying Unreliable Predictions In Clinical Risk Models, Paul D. Myers, Kenney Ng, Kristen Severson, Uri Kartoun, Wangzhi Dai, Wei Huang, Frederick A. Anderson Jr., Collin M. Stultz

Open Access Publications by UMMS Authors

The ability to identify patients who are likely to have an adverse outcome is an essential component of good clinical care. Therefore, predictive risk stratification models play an important role in clinical decision making. Determining whether a given predictive model is suitable for clinical use usually involves evaluating the model's performance on large patient datasets using standard statistical measures of success (e.g., accuracy, discriminatory ability). However, as these metrics correspond to averages over patients who have a range of different characteristics, it is difficult to discern whether an individual prediction on a given patient should be trusted using ...


Digital Commons powered by bepress