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Health-Related Anxiety In The Management Of Oral Soreness In An Hivseropositive Patient, Masita Mandasari, Zulvia Oktanida Syarif, Febrina Rahmayanti 2020 Oral Medicine Residency Program, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia

Health-Related Anxiety In The Management Of Oral Soreness In An Hivseropositive Patient, Masita Mandasari, Zulvia Oktanida Syarif, Febrina Rahmayanti

Journal of Dentistry Indonesia

The number of people living with HIV (PLHIV) has been increasing since the first known case in the early 1980s. However, PLHIV can also experience comorbidities, such as health anxiety. In the oral cavity, anxiety is often associated with the etiology of parafunctional habits. Anxiety can be measured using self-administered instruments, such as the Hospital Anxiety and Depression Scale (HADS) and Short-Health Anxiety Inventory (SHAI), which is specifically used in the medical setting. Objectives: We are describing a case of HIV positive patient with health anxiety who presented to the oral medicine clinic in our hospital with a complaint of …


Erupted Compound Odontoma Associated With Missing Tooth: A Rare Case Report, Weeraya Tantanapornkul, Ruchadaporn Kaomongkolgit, Sirilawan Tohnak, Lalitkorn Promma, Soranan Chantarangsu 2020 Department of Oral Diagnosis, Faculty of Dentistry, Naresiun University, Phitnasulok 65000, Thailand

Erupted Compound Odontoma Associated With Missing Tooth: A Rare Case Report, Weeraya Tantanapornkul, Ruchadaporn Kaomongkolgit, Sirilawan Tohnak, Lalitkorn Promma, Soranan Chantarangsu

Journal of Dentistry Indonesia

Odontomas are one of the most frequently found odontogenic tumors that consist of dental tissues. Odontomas have been classified into two types: compound and complex odontomas. They are usually discovered on routine radiographic examination. In rare cases, the odontoma erupt into the oral cavity, called an erupted odontoma. The first case was published in 1980, and since then, there have been not more than 50 cases being reported in the literature. Most of the reported cases are erupted complex odontoma. This case report represents a rare case of an erupted compound odontoma in a young patient who came with the …


The Effect Of Egf On The Ultrastructure Of Submandibular Salivary Glands Of Albino Rats Receiving Doxorubicin, Mohamed Shamel, Mohamed Mansy, Rabab Mubarak 2020 The British University in Egypt

The Effect Of Egf On The Ultrastructure Of Submandibular Salivary Glands Of Albino Rats Receiving Doxorubicin, Mohamed Shamel, Mohamed Mansy, Rabab Mubarak

Dentistry

Objectives: The present study was designed to detect the outcome of EGF injection on the cytotoxic effect of DXR induced in submandibular SG of rats regarding its ultrastructure. Methods: 30 male Albino rats, two months old and 200gm body weight were divided into three groups. Group I assisted as a control group. Group II (DXRgp), 20 mg/kg body weight DXR was injected intraperitoneally into the rats. Whereas group III (DXR+ EGF) the rats received the same dose of DXR and on the next day, they were injected intraperitoneally with EGF in a daily dose of 10µg/kg bodyweight for 7 consecutive …


Relationship Between Oral Health And Clinical Osteoporosis Among Hospitalized Patients With And Without Diabetes, Kenneth Izoura, Gayle Allenback, Amber Champion, Civon Gewelber, Michael Neubauer 2020 University of Nevada, Las Vegas

Relationship Between Oral Health And Clinical Osteoporosis Among Hospitalized Patients With And Without Diabetes, Kenneth Izoura, Gayle Allenback, Amber Champion, Civon Gewelber, Michael Neubauer

School of Medicine Faculty Publications

Objective: Diabetes mellitus (DM) is associated with poor oral health and osteoporosis (OP). The aim of this study was to assess the relationship between OP, periodontal disease (PD), and other dental and health outcomes in a cohort of hospitalized patients with and without DM. Method: Using a cross-sectional study design, we enrolled consecutive hospitalized patients. We administered a questionnaire to gather demographic information, oral health history, smoking history, and history of OP. We inspected their dentition and reviewed their charts. Data were analyzed using t-tests, chi-square tests, and logistic regression models. Result: Out of 301 patients enrolled, 275 had PD, …


Polymeric Scaffolds For Dental Pulp Tissue Engineering: A Review, Hossein E. Jazayeri, Su-Min Lee, Lauren Kuhn, Farahnaz Fahimipour, Mohammadreza Tahriri, Lobat Tayebi 2020 University of Pennsylvania

Polymeric Scaffolds For Dental Pulp Tissue Engineering: A Review, Hossein E. Jazayeri, Su-Min Lee, Lauren Kuhn, Farahnaz Fahimipour, Mohammadreza Tahriri, Lobat Tayebi

Departmental Papers (Dental)

Objectives: The purpose of this review is to describe recent developments in pulp tissue engineering using scaffolds and/or stem cells. It is crucial to understand how this approach can revitalize damaged dentin-pulp tissue. Widespread scaffold materials, both natural and synthetic, and their fabrication methods, and stem-progenitor cells with the potential of pulp regeneration will be discussed. Data and Sources: A review of literature was conducted through online databases, including MEDLINE by using the PubMed search engine, Scopus, and the Cochrane Library. Study Selection: Studies were selected based on relevance, with a preference given to recent research, particularly from the past …


Implementation Of A Standardized Oral Screening Tool By Pediatric Cardiologists, Shelley McCargar 2020 University of Portland

Implementation Of A Standardized Oral Screening Tool By Pediatric Cardiologists, Shelley Mccargar

Nursing Graduate Publications and Presentations

Background: An examination of procedure cancellations found that the lack of preprocedural oral screening was a preventable cause, for children with congenital heart disease. The purpose of this study was to implement an oral screening tool within the pediatric cardiology clinic, with referral to pediatric dental providers for positive screens. The target population were children age ≥ 6 mo. to < 18 yr. old, being referred for cardiac procedures. Methods: The Quality Implementation Framework method was used for this study design. The multimodal intervention included education, audit and feedback, screening guidelines, environmental support, and interdisciplinary collaboration. Baseline rates for oral screenings were determined by retrospective chart audit from January 2018 to January 2019 (n=211). Adherence to the oral screening tool was the outcome measure. Positive oral screens, resulting in referral to the pediatric dental clinic, were measured as a secondary outcome. Provider compliance rates were used as a process measure. Results: Data collected over 14-weeks showed a 29% increase in documentation of oral screenings prior to referral, as compared to the retrospective chart audit. During the study period 13% of completed screenings were positive (n=5). Provider compliance for the period averaged 70%. Conclusion: A substantial increase in preprocedural oral screenings by pediatric cardiologists was achieved using the Quality Implementation Framework, and targeted interventions.


Effect Of Different Scaling Methods And Materials On The Enamel Surface Topography: An In Vitro Sem Study, Mahmoud Al Ankily, Fatma Makkeyah, Mahmoud Bakr, Mohamed Shamel 2020 The British University in Egypt

Effect Of Different Scaling Methods And Materials On The Enamel Surface Topography: An In Vitro Sem Study, Mahmoud Al Ankily, Fatma Makkeyah, Mahmoud Bakr, Mohamed Shamel

Dentistry

Aims and Objectives: Scaling is important for maintenance of gingival and periodontal conditions. These procedures have a harmful effect on the dental hard tissues. The aim of this study was to investigate the effects of hand and ultrasonic instruments made of stainless and titanium on the surface properties of enamel. Materials and Methods: Forty extracted premolars were used in this in vitro study and were randomly divided into four groups (n = 10). Group I received ultrasonic scaling with stainless steel tip, group II received ultrasonic scaling with titanium tip, group III hand scaling with stainless steel tip, and group …


Effect Of Different Scaling Methods And Materials On The Enamel Surface Topography: An In Vitro Sem Study, Mohamed Shamel, Mahmoud Bakr, Mahmoud Ankily, Fatma Makkeyah 2020 The British University in Egypt

Effect Of Different Scaling Methods And Materials On The Enamel Surface Topography: An In Vitro Sem Study, Mohamed Shamel, Mahmoud Bakr, Mahmoud Ankily, Fatma Makkeyah

Dentistry

Aims and Objectives: Scaling is important for maintenance of gingival and periodontal conditions. These procedures have a harmful effect on the dental hard tissues. The aim of this study was to investigate the effects of hand and ultrasonic instruments made of stainless and titanium on the surface properties of enamel. Materials and Methods: Forty extracted premolars were used in this in vitro study and were randomly divided into four groups (n= 10). Group I received ultrasonic scaling with stainless steel tip, group II received ultrasonic scaling with titanium tip, group III hand scaling with stainless steel tip, and group IV …


Effects Of Aflatoxin B1 On The Submandibular Salivary Gland Of Albino Rats And Possible Therapeutic Potential Of Rosmarinus Officinalis: A Light And Electron Microscopic Study, Mohamed Shamel, Bassant ashraf 2020 The British University in Egypt

Effects Of Aflatoxin B1 On The Submandibular Salivary Gland Of Albino Rats And Possible Therapeutic Potential Of Rosmarinus Officinalis: A Light And Electron Microscopic Study, Mohamed Shamel, Bassant Ashraf

Dentistry

Background: Aflatoxin B1 (AFB1), a highly toxic mycotoxin, is one of the contaminants of food items such as corn, rice, nuts, and flour. This study aimed to evaluate the effect of AFB1 on the histology and ultrastructure of the submandibular salivary glands (SMSG) of albino rats and examine the possible therapeutic effect of Rosmarinus officinalis extract. Methods: This study used 21 adult male albino rats equally divided into three groups as follows: Group C (saline-treated control group); Group A (AFB1 treated group) subjected to intraperitoneal injection of AFB1 (2 mg/kg) once daily for four weeks; Group R …


The Effect Of Smoking On Clinical Presentation And Expression Of Tlr-2 And Cd34 In Oral Lichen Planus Patients: Clinical And Immunohistochemical Study, Enji Ahmed Mahmoud, Nermin Yousif, Nermin Raouf 2020 The British University in Egypt

The Effect Of Smoking On Clinical Presentation And Expression Of Tlr-2 And Cd34 In Oral Lichen Planus Patients: Clinical And Immunohistochemical Study, Enji Ahmed Mahmoud, Nermin Yousif, Nermin Raouf

Dentistry

Background: Oral lichen planus is a chronic inflammatory disease which is considered as a potential precancerous condition. Numerous studies have confirmed that inflammation is a strong risk factor for cancer development. Smoking is associated with potentially malignant disorders of the oral and oropharyngeal mucosa. The adverse consequences of smoking in various pathologies are mediated by its effects on the immune-inflammatory system. Little is known about the influence of cigarette smoke content on the course of OLP and inflammatory response. Methods: Twenty oral lichen planus smoker patients, 20 oral lichen planus non-smoker patients and 20 control patients were included in this …


Neural Egfl Like 1 As A Potential Pro-Chondrogenic, Anti-Inflammatory Dual-Functional Disease-Modifying Osteoarthritis Drug, Chenshuang Li, Zhong Zheng, Pin Ha, Wenlu Jiang, Emily A. Berthiaume, Seungjun Lee, Zane Mills, Hsinchuan Pan, Eric C. Chen, Jie Jiang, Cymbaline T. Culiat, Xinli Zhang, Kang Ting, Chia Soo 2020 University of Pennsylvania

Neural Egfl Like 1 As A Potential Pro-Chondrogenic, Anti-Inflammatory Dual-Functional Disease-Modifying Osteoarthritis Drug, Chenshuang Li, Zhong Zheng, Pin Ha, Wenlu Jiang, Emily A. Berthiaume, Seungjun Lee, Zane Mills, Hsinchuan Pan, Eric C. Chen, Jie Jiang, Cymbaline T. Culiat, Xinli Zhang, Kang Ting, Chia Soo

Departmental Papers (Dental)

Arthritis, an inflammatory condition that causes pain and cartilage destruction in joints, affects over 54.4 million people in the US alone. Here, for the first time, we demonstrated the emerging role of neural EGFL like 1 (NELL-1) in arthritis pathogenesis by showing that Nell-1-haploinsufficient (Nell-1+/6R) mice had accelerated and aggravated osteoarthritis (OA) progression with elevated inflammatory markers in both spontaneous primary OA and chemical-induced secondary OA models. In the chemical-induced OA model, intra-articular injection of interleukin (IL)1β induced more severe inflammation and cartilage degradation in the knee joints of Nell-1+/6R mice than in wildtype animals. Mechanistically, in addition to its …


Integrating Oral Health In Primary Care To Reduce Early Childhood Caries (Ecc): Evidence-Based Guidelines And Recommendations, Alyssa Heiser 2020 Larner College of Medicine at the University of Vermont

Integrating Oral Health In Primary Care To Reduce Early Childhood Caries (Ecc): Evidence-Based Guidelines And Recommendations, Alyssa Heiser

Family Medicine Clerkship Student Projects

Early childhood caries (ECC) is the most common chronic disease affecting children, despite being almost 100% preventable. ECC has become associated with a multi-factorial etiology including poor feeding practices, enamel hypoplasia, oral colonization by cariogenic bacteria, and demineralized tooth structure due to metabolism of sugars by tooth-adherent bacteria. ECC can lead to school absences, poor school performance, difficulty sleeping, attention problems, slower social development, and poor overall health. According to U.S. Preventative Services Task Force (USPSTF) guidelines, all children are at potential risk for developing ECC beginning at the time of first tooth eruption. While there are no validated multivariate …


The Effects Of Vaping On Oral Streptococci And Oral Inflammation, Matthew Caldwell 2020 University of Central Florida

The Effects Of Vaping On Oral Streptococci And Oral Inflammation, Matthew Caldwell

Honors Undergraduate Theses

E-cigarette (e-cig) use is rising, but much is unknown about the effects of its vapor. This vapor contains chemicals such as propylene glycol, a known antimicrobial, and nicotine, whose derivatives are carcinogenic. Here, we study the effects of vaping on resident bacteria of the oral cavity and on oral cell inflammation. Oral streptococci are major residents in the oral cavity, with S. mutans the primary cause of dental caries. Growth and biofilm formation have been shown to be enhanced upon exposure to traditional cigarette smoke in vitro. In this study, we analyzed the effects of e-cig vapor on growth …


Raman Microspectroscopic Study For The Detection Of Oral Field Cancerisation Using Brush Biopsy Samples, Isha Behl, Genecy Calado, Anika Vishwakarma, Stephen Flint, Sheila Galvin, Claire Healy, Marina Leite Pimentel, Alison Malkin, Hugh Byrne, Fiona Lyng 2020 Technological University Dublin

Raman Microspectroscopic Study For The Detection Of Oral Field Cancerisation Using Brush Biopsy Samples, Isha Behl, Genecy Calado, Anika Vishwakarma, Stephen Flint, Sheila Galvin, Claire Healy, Marina Leite Pimentel, Alison Malkin, Hugh Byrne, Fiona Lyng

Articles

Field cancerisation (FC) is potentially an underlying cause of poor treatment outcomes of oral squamous cell carcinoma (OSCC). To explore the phenomenon using Raman microspectroscopy, brush biopsies from the buccal mucosa, tongue, gingiva and alveolus of healthy donors (n = 40) and from potentially malignant lesions (PML) of Dysplasia Clinic patients (n = 40) were examined. Contralateral normal samples (n = 38) were also collected from the patients. Raman spectra were acquired from the nucleus and cytoplasm of each cell, and subjected to partial least squares-discriminant analysis (PLS-DA). High discriminatory accuracy for donor and PML samples was achieved for both …


The Role Of Manganese In Streptococcus Sanguinis, Tanya M. Puccio 2020 Virginia Commonwealth University

The Role Of Manganese In Streptococcus Sanguinis, Tanya M. Puccio

Theses and Dissertations

Streptococcus sanguinis is primarily associated with oral health as a commensal bacterium. As an opportunistic pathogen, S. sanguinis is capable of colonizing heart valve vegetations, leading to the disease infective endocarditis. Previous studies from our lab have identified the high-affinity manganese transporter SsaACB as important for endocarditis virulence. The impact that manganese depletion has on S. sanguinis had never been evaluated and a secondary manganese transporter has not been identified. Thus, we employed the use of a fermentor to control large-scale growth over time and depleted manganese in an ΔssaACB mutant using a metal chelator, EDTA. The changes in …


Selenomonas Sputigena: Growth Conditions And Projected Virulence Factors Of An Emerging Oral Pathogen, Kayla A. Keller 2020 Virginia Commonwealth University

Selenomonas Sputigena: Growth Conditions And Projected Virulence Factors Of An Emerging Oral Pathogen, Kayla A. Keller

Theses and Dissertations

Periodontal diseases are ubiquitous diseases. They can affect people through a chronic infection that happens over a lifetime, but also as an aggressive infection that afflicts the younger population. It not only results in tooth loss and a lower quality of life, but it can also lead to fatal secondary infections like cervical cancer, heart disease, and Alzheimer’s disease. This study looks at Selenomonas sputigena, an emerging oral pathogen, that has been hypothesized to contribute to periodontal disease. It has been linked to fatal septicemia and has been found in increased abundance within the oral biofilm during peak infection. …


Antimicrobial Efficacy Of Myrmecodia Pendens Extract And Fraction Combination Against Enterococcus Faecalis Atcc 29212, Faisal Kuswandani, Mieke H. Satari, Ani M. Maskoen 2019 Biomedical Science Master Program, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java 45363, Indonesia

Antimicrobial Efficacy Of Myrmecodia Pendens Extract And Fraction Combination Against Enterococcus Faecalis Atcc 29212, Faisal Kuswandani, Mieke H. Satari, Ani M. Maskoen

Journal of Dentistry Indonesia

Enterococcus faecalis can withstand harsh environmental conditions in the root canal and cause a secondary infection. Myrmecodia pendens is an herbal medicine rich in polyphenol compounds that have antibacterial, antioxidant, and anticancer properties. Objectives: To analyze the effects of M. pendens fraction combination on the sensitivity of E. faecalis. Methods: The minimum inhibitory concentration (MIC) was determined using a serial microdilution method, and the minimum bactericidal concentration (MBC) was determined by adding the test sample to sterile Mueler Hinton agar medium. Results: The MIC of combination 1 (hexane-ethyl acetate, HE) was 0.049 mg/mL, whereas those of combinations 2 (hexane-water, HA) …


Persistent Endodontics Pathogens Biofilm Inhibited By Lactobacillus Reuteri Indonesian Strain, Armelia Sari Widyarman, Njoo Kiky Elysia Lazaroni 2019 Department of Microbiology, Faculty of Dentistry, Trisakti University, Jakarta, 11440 Indonesia

Persistent Endodontics Pathogens Biofilm Inhibited By Lactobacillus Reuteri Indonesian Strain, Armelia Sari Widyarman, Njoo Kiky Elysia Lazaroni

Journal of Dentistry Indonesia

Lactobacillus reuteri is known as probiotics that effective to improve oral health. Objective: To analyze the effect of L. reuteri Indonesian strain, towards Enterococcus faecalis and Candida albicans biofilm growth. Methods: This study was conducted using biofilm assay. Each E. faecalis ATCC-29212 and C. albicans ATCC-10231 were cultured in Brain Heart Infusion Broth, distributed into 96 well-microplate and incubated for 24h, 37°C, anaerobic condition for E. faecalis and aerobic condition for C. albicans. L. reuteri LC382415 (Indonesian strain) was cultured in deMann Rogosa Shar pe Broth and diluted into different concentrations (108,106, and 104 …


Orthodontic Camouflage Treatment Of A High-Angle Severe Skeletal Class Ii Discrepancy, Deryana Marshadhianti, Miesje Karmiati Purwanegara 2019 Orthodontics Residency Program, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430 Indonesia

Orthodontic Camouflage Treatment Of A High-Angle Severe Skeletal Class Ii Discrepancy, Deryana Marshadhianti, Miesje Karmiati Purwanegara

Journal of Dentistry Indonesia

Proper orthodontic treatment in adult patients with severe skeletal Class II discrepancy can be challenging. Recently, miniscrew implants have been used as a strategy to treat skeletal Class II patients. Objective: This report illustrates a skeletal Class II malocclusion management combining straight wire technique and miniscrew implant anchorage. Case report: The patient was a 21-years- old Indonesian female with Class II skeletal discrepancy, a retrognathic mandible, a high mandibular plane angle, and a mouth breathing habit due to a history of allergic rhinitis. Anchorage control is important in the sagittal and vertical directions. Miniscrew implants were placed in the …


Medical Conditions And Oral Diseases In Elderly Thai Dental Patients In Lower Northern Thailand, Ruchadaporn Kaomongkolgit, Pissacha Daroonpan, Weeraya Tantanapornkul, Jadesada Palasuk, Ronnayut Chansamat 2019 Department of Oral Diagnosis, Faculty of Dentistry, Naresuan University, Phitsanulok 65000, Thailand

Medical Conditions And Oral Diseases In Elderly Thai Dental Patients In Lower Northern Thailand, Ruchadaporn Kaomongkolgit, Pissacha Daroonpan, Weeraya Tantanapornkul, Jadesada Palasuk, Ronnayut Chansamat

Journal of Dentistry Indonesia

The World Health Organization (WHO) aims to strengthen oral health promotion and disease prevention around the globe. The prevalence and association of systemic diseases and oral diseases has been reported. Objectives: The objectives of this study were to investigate prevalence of medical conditions and oral diseases in elderly Thai dental patients. Methods: Three hundred dental records of patient aged 60 years old and older were retrospectively reviewed. Data were analyzed using Pearson’s Chi-square and Fisher›s exact test with the significant level at p < 0.05. Results: All of them were Thai of 142 males (47.3%) and 158 females (52.7%). Their age ranged …


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